Vol 8, No 45

Advances in lung cancer

Getting a GRP on histone deacetylase inhibitor selectivity

Minimal residual disease in pediatric ALL

Salvage therapy for relapsed testicular cancer

Which second line treatments after ESA failure?

Bcr-Abl: one kinase, two isoforms, two diseases

Hyperhaploid karyotypes in multiple myeloma

Second cancer risk following Hodgkin lymphoma

Endometriosis: benign, malignant, or something in between?

CBP501 induces immunogenic tumor cell death and CD8 T cell infiltration into tumors in combination with platinum, and increases the efficacy of immune checkpoint inhibitors against tumors in mice

Apigenin enhances skeletal muscle hypertrophy and myoblast differentiation by regulating Prmt7

TAp63γ and ΔNp63γ are regulated by RBM38 via mRNA stability and have an opposing function in growth suppression

Mitoketoscins: Novel mitochondrial inhibitors for targeting ketone metabolism in cancer stem cells (CSCs)

Metapristone (RU486 metabolite) suppresses NSCLC by targeting EGFR-mediated PI3K/AKT pathway

Regulation of SIRT3 signal related metabolic reprogramming in gastric cancer by Helicobacter pylori oncoprotein CagA

The autophagic inhibition oral squamous cell carcinoma cancer growth of 16-hydroxy-cleroda-3,14-dine-15,16-olide

The circRNA interactome–innovative hallmarks of the intra- and extracellular radiation response

Sites of extranodal involvement are prognostic in patients with stage 1 follicular lymphoma

Interactions between vitamin D receptor (VDR) gene and Interleukin-6 gene and environment factors on coronary heart disease risk in a Chinese Han population

Nationwide cohort study on the epidemiology and survival outcomes of thyroid cancer

Identification of volasertib-resistant mechanism and evaluation of combination effects with volasertib and other agents on acute myeloid leukemia

Characterization and functional analysis of a slow-cycling subpopulation in colorectal cancer enriched by cell cycle inducer combined chemotherapy

Silencing heme oxygenase-1 increases the sensitivity of ABC-DLBCL cells to histone deacetylase inhibitor in vitro and in vivo

TIPE1 function as a prognosis predictor and negative regulator of lung cancer

Reversion of epithelial-mesenchymal transition by a novel agent DZ-50 via IGF binding protein-3 in prostate cancer cells

MRP4 regulates ENaC-dependent CREB/COX-2/PGE₂ signaling during embryo implantation

Regulator of G protein signaling 4 inhibits human melanoma cells proliferation and invasion through the PI3K/AKT signaling pathway

Prognostic relevance of androgen receptor expression in renal cell carcinomas

STK38L kinase ablation promotes loss of cell viability in a subset of KRAS-dependent pancreatic cancer cell lines

Local irradiation does not enhance the effect of immunostimulatory AdCD40L gene therapy combined with low dose cyclophosphamide in melanoma patients

Clinical significance of lncRNA-ATB expression in human hepatocellular carcinoma

Circulating exosomal microRNA-203 is associated with metastasis possibly via inducing tumor-associated macrophages in colorectal cancer

Identification of LRP-1 as an endocytosis and recycling receptor for β1-integrin in thyroid cancer cells

The impacts of genetic polymorphisms in genes of base excision repair pathway on the efficacy and acute toxicities of (chemo)radiotherapy in patients with nasopharyngeal carcinoma

Comprehensive bioinformatics analysis of the characterization and determination underlying mechanisms of over-expression and co-expression of genes residing on 20q in colorectal cancer

Sphingosine kinase 1 mediates AGEs-induced fibronectin upregulation in diabetic nephropathy

Regulation of neuroinflammation by matrix metalloproteinase-8 inhibitor derivatives in activated microglia and astrocytes

Transcriptional signature of lymphoblastoid cell lines of BRCA1, BRCA2 and non-BRCA1/2 high risk breast cancer families

Copy number variations and expression of MPDZ are prognostic biomarkers for clear cell renal cell carcinoma

Angiotensin-converting enzyme-2 overexpression improves atrial electrical remodeling through TRPM7 signaling pathway

The coiled-coil domain of oncogene RASSF 7 inhibits hippo signaling and promotes non-small cell lung cancer

Association of PPP1R13L and CD3EAP polymorphisms with risk and survival of non-small cell lung cancer in Chinese non-smoking females

ERp29 inhibits tumorigenicity by suppressing epithelial mesenchymal transition in gastric cancer

lncRNAs PVT1 and HAR1A are prognosis biomarkers and indicate therapy outcome for diffuse glioma patients

Cellular inhibitor of apoptosis protein 2 promotes the epithelial-mesenchymal transition in triple-negative breast cancer cells through activation of the AKT signaling pathway

The systemic tumor response to RNase A treatment affects the expression of genes involved in maintaining cell malignancy

Beta-catenin represses protein kinase D1 gene expression by non-canonical pathway through MYC/MAX transcription complex in prostate cancer

Inherent characteristics of metachronous metastatic renal cell carcinoma in the era of targeted agents

Microarray analyses reveal genes related to progression and prognosis of esophageal squamous cell carcinoma

S-adenosylmethionine and methylthioadenosine inhibit cancer metastasis by targeting MicroRNA 34a/b-methionine adenosyltransferase 2A/2B axis

Hypoxia-related biological markers as predictors of epirubicin-based treatment responsiveness and resistance in locally advanced breast cancer

Up-regulated expression of oxytocin mRNA in peripheral blood lymphocytes from first-episode schizophrenia patients

Sensitive droplet digital PCR method for detection of TERT promoter mutations in cell free DNA from patients with metastatic melanoma

Chromosome preference of disease genes and vectorization for the prediction of non-coding disease genes

Functional imaging in combination with mutation status aids prediction of response to inhibiting B-cell receptor signaling in lymphoma

Increased SNAT1 is a marker of human osteosarcoma and potential therapeutic target

Exome sequencing identified a novel missense mutation c.464G>A (p.G155D) in Ca²⁺-binding protein 4 (CABP4) in a Chinese pedigree with autosomal dominant nocturnal frontal lobe epilepsy

Epstein–Barr virus BRLF1 induces genomic instability and progressive malignancy in nasopharyngeal carcinoma cells

Size-based detection of sarcoma circulating tumor cells and cell clusters

Trimethylation of H3K27 during human cerebellar development in relation to medulloblastoma

Frizzled 8 promotes the cell proliferation and metastasis of renal cell carcinoma

IGF-IEc expression is increased in secondary compared to primary foci in neuroendocrine neoplasms

Combination of sorafenib and TACE inhibits portal vein invasion for intermediate stage HCC: a single center retrospective controlled study

Overexpression of miR-26b decreases the cisplatin-resistance in laryngeal cancer by targeting ATF2

Chronic polycyclic aromatic hydrocarbon exposure causes DNA damage and genomic instability in lung epithelial cells

PARK14 PLA2G6 mutants are defective in preventing rotenone-induced mitochondrial dysfunction, ROS generation and activation of mitochondrial apoptotic pathway

Clinical significance of cripto-1 expression in lung adenocarcinoma

An endoscopic ultrasonography-guided interstitial brachytherapy based special treatment-planning system for unresectable pancreatic cancer

A novel “total pituitary hormone index” as an indicator of postoperative pituitary function in patients undergoing resection of pituitary adenomas

Azacitidine or intensive chemotherapy for older patients with secondary or therapy-related acute myeloid leukemia

Gap in gender parity: gender disparities in incidence and clinical impact of chronic total occlusion in non-infarct artery in patients with non-ST-segment elevation myocardial infarction and multivessel coronary artery disease

Predicting level 2 axillary lymph node metastasis in a Chinese breast cancer population post-neoadjuvant chemotherapy: development and assessment of a new predictive nomogram

Relationship of polymorphisms and haplotype in interleukin-16 and adiponectin gene with late-onset Alzheimer’s disease risk

Comparison of two transarterial chemoembolization regimens in patients with unresectable hepatocellular carcinoma: raltitrexed plus oxaliplatin versus 5-fluorouracil plus oxaliplatin

Phase I/Ib study of olaparib and carboplatin in women with triple negative breast cancer

Myelodysplastic syndromes: advantages of a combined cytogenetic and molecular diagnostic workup

Serum miR-143 levels predict the pathological response to neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer

Different patterns of age-related central olfactory decline in men and women as quantified by olfactory fMRI

Cost and cost-effectiveness of adjuvant trastuzumab in the real world setting: A study of the Southeast Netherlands Breast Cancer Consortium

Preoperative lymphocyte-to-monocyte ratio as a strong predictor of survival and recurrence for gastric cancer after radical-intent surgery

Anesthetic dreaming, anesthesia awareness and patient satisfaction after deep sedation with propofol target controlled infusion: A prospective cohort study of patients undergoing day case breast surgery

Evaluating the efficacy of post-surgery adjuvant therapies used for ductal carcinoma in situ patients: a network meta-analysis

CT-guided microwave ablation through the lungs for treating liver tumors near the diaphragm

The prostate health index PHI predicts oncological outcome and biochemical recurrence after radical prostatectomy - analysis in 437 patients

Association between obesity and trastuzumab-related cardiac toxicity in elderly patients with breast cancer

A phase 2 study of the first imipridone ONC201, a selective DRD2 antagonist for oncology, administered every three weeks in recurrent glioblastoma

Weekly paclitaxel and cisplatin as neoadjuvant chemotherapy with locally advanced breast cancer: a prospective, single arm, phase II study

Significance of the thrombo-inflammatory status-based novel prognostic score as a useful predictor for in-hospital mortality of patients with type B acute aortic dissection

Remote ischemic conditioning for the prevention of contrast-induced acute kidney injury in patients undergoing intravascular contrast administration: a meta-analysis and trial sequential analysis of 16 randomized controlled trials

Tumor necrosis and complete resection has significant impacts on survival in patients with limited-stage upper aerodigestive tract NK/T cell lymphoma

Skeletal abnormalities detected by SPECT is associated with increased relapse risk in pediatric acute lymphoblastic leukemia

Utility of endoscopic ultrasound-guided fine-needle aspiration of regional lymph nodes that are proximal to and far from the primary distal esophageal carcinoma

Prognostic value of systemic inflammation score in patients with hepatocellular carcinoma after hepatectomy

Ultrasound guided percutaneous microwave ablation of benign breast lesions

Prognostic value of number of negative lymph node in patients with stage II and IIIa non-small cell lung cancer

Intraoperative use of dexmedetomidine promotes postoperative sleep and recovery following radical mastectomy under general anesthesia

Detection of tumor-derived DNA dispersed in the airway improves the diagnostic accuracy of bronchoscopy for lung cancer

Can we consider discontinuation of hypomethylating agents in patients with myelodysplastic syndrome : a retrospective study from The Korean Society of Hematology AML/MDS Working Party

Association study of inflammatory cytokine and chemokine expression in hand foot and mouth disease

The predictive efficacy of hypoechoic lesion in ultrasound for prostate cancer in Chinese people: five-year experience in a moderated 10-core transperineal prostate biopsy procedure

Skeletal muscle depletion predicts survival of patients with advanced biliary tract cancer undergoing palliative chemotherapy

Age-adjusted Charlson comorbidity index score as predictor of survival of patients with digestive system cancer who have undergone surgical resection

Ratio of positive lymph nodes: The prognostic value in stage IV thyroid cancer

Serum dickkopf-1 as a clinical and prognostic factor in non-small cell lung cancer patients with bone metastases

Evaluation of the branched-chain amino acid-to-tyrosine ratio prior to treatment as a prognostic predictor in patients with liver cirrhosis

MMP-3 gene polymorphisms are associated with increased risk of osteoarthritis in Chinese men

Risk of acute myocardial infarction in upper tract urothelial carcinoma patients receiving radical nephroureterectomy: a population-based cohort study

Surgical management for follicular variant of papillary thyroid carcinoma

The role of frontline autologous stem cell transplantation for primary plasma cell leukemia: a retrospective multicenter study (KMM160)

Whether low-dose metronomic oral cyclophosphamide improves the response to docetaxel in first-line treatment of non-triple-negative metastatic breast cancer

Impact of pretreatment plasma D-dimer levels and its perioperative change on prognosis in operable esophageal squamous cell carcinoma

Phase I dose-escalation study of the c-Met tyrosine kinase inhibitor SAR125844 in Asian patients with advanced solid tumors, including patients with MET-amplified gastric cancer

A three gene immunohistochemical panel serves as an adjunct to clinical staging of patients with head and neck cancer

Prognostic factors influencing the survival of patients with carcinoma of the gastric cardia receiving preoperative interventional embolization chemotherapy

Elevated hemoglobin glycation index identify non-diabetic individuals at increased risk of kidney dysfunction

Prevalence of prenatally diagnosed congenital cystic adenomatoid malformation among fetuses in China

Consideration of clinicopathologic features improves patient stratification for multimodal treatment of gastric cancer

Positive Helicobacter pylori status is associated with better overall survival for gastric cancer patients: evidence from case-cohort studies

Left-sided primary tumor is a favorable prognostic factor for metastatic colorectal cancer patients receiving surgery

Comparison of biological target volume metrics based on FDG PET-CT and 4DCT for primary non-small-cell lung cancer

Effect of Amygdalus scoparia kernel oil consumption on lipid profile of the patients with dyslipidemia: a randomized, open-label controlled clinical trial

Diffusion-weighted MR imaging in prediction of response to neoadjuvant chemotherapy in patients with breast cancer

MRI-based evaluation of multiorgan iron overload is a predictor of adverse outcomes in pediatric patients undergoing allogeneic hematopoietic stem cell transplantation

Improved survival with higher radiation dose for esophageal squamous cell carcinoma patients treated with definitive chemoradiotherapy

Mammography and ultrasound effective features in differentiating basal-like and normal-like subtypes of triple negative breast cancer

Decreased risk of dementia in migraine patients with traditional Chinese medicine use: a population-based cohort study

Excessive daytime sleepiness and metabolic syndrome in men with obstructive sleep apnea: a large cross-sectional study

Endostar in combination with postoperative adjuvant chemotherapy prolongs the disease free survival of stage IIIA NSCLC patients with high VEGF expression

Generating a robust prediction model for stage I lung adenocarcinoma recurrence after surgical resection

Preoperative neutrophil-to-lymphocyte ratio and tumor-related factors to predict microvascular invasion in patients with hepatocellular carcinoma

Evaluation of real-world treatment outcomes in patients with distant metastatic Merkel cell carcinoma following second-line chemotherapy in Europe

Ultrasound-guided percutaneous microwave ablation assisted by three-dimensional visualization operative treatment planning system and percutaneous transhepatic cholangial drainage with intraductal chilled saline perfusion for larger hepatic hilum hepatocellular (D ≥ 3 cm): preliminary results

A phase I clinical trial of binimetinib in combination with FOLFOX in patients with advanced metastatic colorectal cancer who failed prior standard therapy

Radiotherapy for T3N0 glottic carcinoma without cord fixation: elective nodal irradiation or not?

Influence of angiographic spontaneous coronary reperfusion on long-term prognosis in patients with ST-segment elevation myocardial infarction

Mid-arm muscle circumference as a surrogate in predicting insulin resistance in non-obese elderly individuals

Surgical resection of primary tumor improves survival of pancreatic neuroendocrine tumor with liver metastases

Prediction of radio-responsiveness with immune-profiling in patients with rectal cancer

Loneliness and its impact on quality of life in Chinese heroin-dependent patients receiving methadone maintenance treatment

Baseline relative eosinophil count as a predictive biomarker for ipilimumab treatment in advanced melanoma

The degree of hepatic arterial blood supply of portal vein tumor thrombus in patients with hepatocellular carcinoma and its impact on overall survival after transarterial chemoembolization

The impact of post-radioiodine therapy SPECT/CT on early risk stratification in differentiated thyroid cancer; a bi-institutional study

A 3-year observation of testosterone deficiency in Chinese patients with chronic heart failure

Neural correlates of childhood trauma with executive function in young healthy adults

Comparison on efficacy of radical prostatectomy versus external beam radiotherapy for the treatment of localized prostate cancer

Phase I clinical trial of the base excision repair inhibitor methoxyamine in combination with fludarabine for patients with advanced hematologic malignancies

Nephroureterectomy increase 5 year survival in patients on dialysis with upper urinary tract urothelial carcinoma

Prevalence of malnutrition in patients at first medical oncology visit: the PreMiO study

Clinical value and indication for the dissection of lymph nodes posterior to the right recurrent laryngeal nerve in papillary thyroid carcinoma

Aberrant patterns of brain cerebral blood flow in Chinese han first-episode drug-naïve depressive patients with and without a family history of depression

Conditional survival estimate in patients with Barcelona Clinic Liver Cancer stage B/C hepatocellular carcinoma treated with hepatic arterial infusion chemotherapy with/without concurrent radiotherapy

Long-term postoperative survival prediction in patients with colorectal liver metastasis

Association between postoperative hyponatremia and renal prognosis in major urologic surgery

Pain of methadone-maintained heroin addicts: lonelier individuals feel more intense pain

Comparing the efficacy of induction-concurrent with concurrent-adjuvant chemotherapy in locoregionally advanced nasopharyngeal carcinoma: a propensity score matching analysis

Preoperative risk factors for massive blood loss in adrenalectomy for pheochromocytoma

Postoperative adjuvant radiotherapy is associated with improved survival in hepatocellular carcinoma with microvascular invasion

Peri-treatment change of anorectal function in patients with rectal cancer after preoperative chemoradiotherapy

Long-term prognosis of Guillain-Barré syndrome not determined by treatment options?

Clinicopathologic features and prognostic factors for patients with colorectal cancer who are 75 years and older

Prospective evaluation of skin toxicities in patients receiving post-mastectomy irradiation of chest wall, supra/infraclavicular and internal mammary nodes delivered by conventional versus intensity-modulated radiotherapy technique

Efficacy, safety and proper dose analysis of PEGylated granulocyte colony-stimulating factor as support for dose-dense adjuvant chemotherapy in node positive Chinese breast cancer patients

Short- and long-term outcomes of laparoscopy-assisted versus open total gastrectomy for gastric cancer: a propensity score-matched analysis

Single nucleotide polymorphisms in MLH1 predict poor prognosis of hepatocellular carcinoma in a Chinese population

A preoperative scoring system to predict the risk of No.10 lymph node metastasis for advanced upper gastric cancer: a large case report based on a single-center study

The impact of delayed commencement of adjuvant chemotherapy (eight or more weeks) on survival in stage II and III colon cancer: a national population-based cohort study

Hodgkin lymphoma in adolescent and young adults: insights from an adult tertiary single-center cohort of 349 patients

High truncated-O-glycan score predicts adverse clinical outcome in patients with localized clear-cell renal cell carcinoma after surgery