Oncotarget

Clinical Research Papers:

Ultrasound guided percutaneous microwave ablation of benign breast lesions

Jie Yu _, Bao-Hua Chen, Jing Zhang, Zhi-Yu Han, Han Wu, Yan Huang, Meng-Juan Mu and Ping Liang

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Oncotarget. 2017; 8:79376-79386. https://doi.org/10.18632/oncotarget.18123

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Abstract

Jie Yu1,*, Bao-Hua Chen2,*, Jing Zhang1, Zhi-Yu Han1, Han Wu1, Yan Huang2, Meng-Juan Mu1 and Ping Liang1

1 Department of Interventional Ultrasound, Chinese PLA General Hospital, Beijing, China

2 Department of General Surgery, The People’s Liberation Army One Eight Four Hospital, Yingtan, China

* These authors have contributed equally to the manuscript

Correspondence to:

Jie Yu, email:

Ping Liang, email:

Keywords: breast, benign, microwave ablation, ultrasound, volume reduction

Received: January 05, 2017 Accepted:April 12, 2017 Published: May 23, 2017

Abstract

The benign breast lesions (BBLs) share a high incidence for women and therapy methods with minimal invasion and better cosmetic

outcome are thirsted for. In this study, 122 patients with 198 biopsy-proved BBLs were enrolled. Ultrasound (US)-guided microwave ablation (MWA) was performed with local anesthesia from November, 2013 to April, 2016. The mean longest tumor size assessed was 1.6±0.7 cm (ranging 0.7-4.9 cm). MWA was successfully performed in all cases including 85 lesions adjacent to the skin, pectoralis and areola. The mean ablation time was 3.2mins (ranging 0.5-18.3 mins). 99.5% of BBLs showed complete ablation when assessed by magnetic resonance imaging and 100% of them by US. At the median 14-month follow-up, the BBLs were not palpable in 45.9 % of the cases (palpable in 90.2 % of the cases before MWA) and the mean volume reduction ratio was 78.4±33.5% for total lesions and 89.3±20.8%, 84.7±27.6% and 55.9±32.9% for ≤1.0 cm, 1.1-2.0cm and >2.0 cm lesions in 12-month follow-up, respectively. Cosmesis were reported as good or excellent in 100 % by physician and patients. No side effect was found. The MWA of the BBLs proved feasible and effective, while showing meaningful reduction in volume, palpability and cosmetic satisfying outcomes.


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