Vol 8, No 28

Aminochrome as preclinical model for Parkinson's disease

Ca²⁺ activated Cl^- channels as targets for analgesics

Epigenetic control of epileptogenesis by miR-146a

Targeting the proteasome in epilepsy

Adult neurogenesis in intellectual disabilities

P-glycoprotein attenuates DNA repair activity in multidrug-resistant cells by acting through the Cbp-Csk-Src cascade

Targeting of apoptotic pathways by SMAC or BH3 mimetics distinctly sensitizes paclitaxel-resistant triple negative breast cancer cells

Egr-1 and RNA POL II facilitate glioma cell GDNF transcription induced by histone hyperacetylation in promoter II

Lysosomal accumulation of anticancer drugs triggers lysosomal exocytosis

Triptolide mitigates radiation-induced pneumonitis via inhibition of alveolar macrophages and related inflammatory molecules

Significant association between lncRNA H19 polymorphisms and cancer susceptibility: a meta-analysis

Error-prone DNA polymerase and oxidative stress increase the incidences of A to G mutations in tumors

Cytokine-induced killer cells/dendritic cells-cytokine induced killer cells immunotherapy combined with chemotherapy for treatment of colorectal cancer in China: a meta-analysis of 29 trials involving 2,610 patients

Significance of inflammation-based indices in the prognosis of patients with non-metastatic colorectal cancer

Prospective serum metabolomic profile of prostate cancer by size and extent of primary tumor

Mesenchymal stem cells release exosomes that transfer miRNAs to endothelial cells and promote angiogenesis

Knockdown of miR-27a sensitizes colorectal cancer stem cells to TRAIL by promoting the formation of Apaf-1-caspase-9 complex

MiR-29b inhibits the growth of glioma via MYCN dependent way

Transarterial chemoembolization combined with Jie-du granule preparation improves the survival outcomes of patients with unresectable hepatocellular carcinoma

Association of the VDAC3 gene polymorphism with sperm count in Han-Chinese population with idiopathic male infertility

ERK expression and its correlation with STAT1 in esophageal squamous cell carcinoma

Identification of C21orf59 and ATG2A as novel determinants of renal function-related traits in Japanese by exome-wide association studies

Epithelial-mesenchymal transition induced by GRO-α-CXCR2 promotes bladder cancer recurrence after intravesical chemotherapy

TIAM1 variants improve clinical outcome in neuroblastoma

Migration pattern, actin cytoskeleton organization and response to PI3K-, mTOR-, and Hsp90-inhibition of glioblastoma cells with different invasive capacities

Temporal and spatial changes of cells positive for stem-like markers in different compartments and stages of human colorectal adenoma-carcinoma sequence

PI3K inhibitor enhances the cytotoxic response to etoposide and cisplatin in a newly established neuroendocrine cervical carcinoma cell line

Can preoperative and postoperative CA19-9 levels predict survival and early recurrence in patients with resectable hilar cholangiocarcinoma?

A novel serum based biomarker panel has complementary ability to preclude presence of early lung cancer for low dose CT (LDCT)

Zbtb38 is a novel target for spinal cord injury

Novel circular RNA expression profiles reflect progression of patients with hypopharyngeal squamous cell carcinoma

TRIM32 affects the recovery of motor function following spinal cord injury through regulating proliferation of glia

Advance directives: cancer patients’ preferences and family-based decision making

Circulating microRNAs as novel biomarkers of ALK-positive non-small cell lung cancer and predictors of response to crizotinib therapy

Mesenchymal stem cell carriers enhance antitumor efficacy of oncolytic adenoviruses in an immunocompetent mouse model

ADCC responses and blocking of EGFR-mediated signaling and cell growth by combining the anti-EGFR antibodies imgatuzumab and cetuximab in NSCLC cells

Arsenic trioxide and angiotensin II have inhibitory effects on HERG protein expression: Evidence for the role of PML SUMOylation

Overexpression of a novel candidate oncogene KIF14 correlates with tumor progression and poor prognosis in prostate cancer

The effect of rapamycin, NVP-BEZ235, aspirin, and metformin on PI3K/AKT/mTOR signaling pathway of PIK3CA-related overgrowth spectrum (PROS)

ROS enhance angiogenic properties via regulation of NRF2 in tumor endothelial cells

DNA methylation mediated silencing of microRNA-874 is a promising diagnosis and prognostic marker in breast cancer

Anti-complement component 5 antibody targeting MG4 domain inhibits choroidal neovascularization

Inhibitory effect of ethanol extract of Nannochloropsis oceanica on lipopolysaccharide-induced neuroinflammation, oxidative stress, amyloidogenesis and memory impairment

Polymorphisms of VDR gene and risk of gastric cardiac adenocarcinoma in Chinese population

Molecular characterization of circulating tumor cells from patients with metastatic breast cancer reflects evolutionary changes in gene expression under the pressure of systemic therapy

12-O-tetradecanoylphorbol-13-acetate (TPA) increases murine intestinal crypt stem cell survival following radiation injury

Prognostic value of transglutaminase 2 in non-small cell lung cancer patients

Lymph nodes ratio based nomogram predicts survival of resectable gastric cancer regardless of the number of examined lymph nodes

Enhanced antitumor efficacy of cisplatin for treating ovarian cancer in vitro and in vivo via transferrin binding

The varicella vaccination pattern among children under 5 years old in selected areas in china

Sequencing of cancer cell subpopulations identifies micrometastases in a bladder cancer patient

Xenogeneic human umbilical cord-derived mesenchymal stem cells reduce mortality in rats with acute respiratory distress syndrome complicated by sepsis

Ubenimex enhances Brd4 inhibition by suppressing HEXIM1 autophagic degradation and suppressing the Akt pathway in glioma cells

Inhibition of stress-inducible HSP70 impairs mitochondrial proteostasis and function

Toll-like receptor genetic variations in bone marrow transplantation

NRAS mutations in cutaneous T cell lymphoma (CTCL) sensitize tumors towards treatment with the multikinase inhibitor Sorafenib

Mucinous adenocarcinoma and non-mucinous adenocarcinoma: differing clinicopathological characteristics and computed tomography features in gastric cancer

Increased S100A15 expression and decreased DNA methylation of its gene promoter are involved in high metastasis potential and poor outcome of lung adenocarcinoma

miR-551b regulates epithelial-mesenchymal transition and metastasis of gastric cancer by inhibiting ERBB4 expression

Clinically significant sub-clonality for common drivers can be detected in 26% of KRAS/EGFR mutated lung adenocarcinomas

Dual-negative expression of Nrf2 and NQO1 predicts superior outcomes in patients with non-small cell lung cancer

Extracellular pH is a biomarker enabling detection of breast cancer and liver cancer using CEST MRI

Impact of age on the diagnostic performances and cut-offs of APRI and FIB-4 for significant fibrosis and cirrhosis in chronic hepatitis B

Prognostic significance of subclassification of stage IIB lung cancer: a retrospective study of 226 patients

Targeted next generation sequencing identifies somatic mutations and gene fusions in papillary thyroid carcinoma

Quantitative proteomics profiling reveals activation of mTOR pathway in trastuzumab resistance

Circulating plasma microRNAs as potential markers to identify EGFR mutation status and to monitor epidermal growth factor receptor-tyrosine kinase inhibitor treatment in patients with advanced non-small cell lung cancer

Tumor cell-specific AIM2 regulates growth and invasion of cutaneous squamous cell carcinoma

Notch1 regulates the JNK signaling pathway and increases apoptosis in hepatocellular carcinoma

Regulation of CD44v6 expression in gastric carcinoma by the IL-6/STAT3 signaling pathway and its clinical significance

FAM3A enhances adipogenesis of 3T3-L1 preadipocytes via activation of ATP-P2 receptor-Akt signaling pathway

Combined treatment with artesunate and bromocriptine has synergistic anticancer effects in pituitary adenoma cell lines

Radiomic model for predicting mutations in the isocitrate dehydrogenase gene in glioblastomas

Molecular dissection of effector mechanisms of RAS-mediated resistance to anti-EGFR antibody therapy

High expression of long non-coding RNA NEAT1 indicates poor prognosis of human cancer

Cytokine-mediated activation of human ex vivo-expanded Vγ9Vδ2 T cells

ARID1B alterations identify aggressive tumors in neuroblastoma

The novel complex combination of alum, CpG ODN and HH2 as adjuvant in cancer vaccine effectively suppresses tumor growth in vivo

Methyl jasmonate leads to necrosis and apoptosis in hepatocellular carcinoma cells via inhibition of glycolysis and represses tumor growth in mice

Dihydroartemisinin induces autophagy-dependent death in human tongue squamous cell carcinoma cells through DNA double-strand break-mediated oxidative stress

The impact of interleukin-10 (IL-10) gene 4 polymorphisms on peripheral blood IL-10 variation and prostate cancer risk based on published studies

Fixed differences in the 3'UTR of buffalo PRNP gene provide binding sites for miRNAs post-transcriptional regulation

Circulating soluble programmed death-1 levels may differentiate immune-tolerant phase from other phases and hepatocellular carcinoma from other clinical diseases in chronic hepatitis B virus infection

CNOT2 promotes degradation of p62/SQSTM1 as a negative regulator in ATG5 dependent autophagy

Chaetocin enhances dendritic cell function via the induction of heat shock protein and cancer testis antigens in myeloma cells

Quantitative prediction of oral cancer risk in patients with oral leukoplakia

Activating MAPK1 (ERK2) mutation in an aggressive case of disseminated juvenile xanthogranuloma

A high-throughput method to detect RNA profiling by integration of RT-MLPA with next generation sequencing technology

Killing effects of Huaier Granule combined with DC-CIK on nude mice transplanted with colon carcinoma cell line

Long non-coding RNA HOXA-AS2 promotes proliferation and invasion of breast cancer by acting as a miR-520c-3p sponge

An unusual intragenic promoter of PIWIL2 contributes to aberrant activation of oncogenic PL2L60

Oncogenic MNK signalling regulates the metastasis suppressor NDRG1

Identification of novel long non-coding RNA biomarkers for prognosis prediction of papillary thyroid cancer

Bioinformatics and in vitro experimental analyses identify the selective therapeutic potential of interferon gamma and apigenin against cervical squamous cell carcinoma and adenocarcinoma

5azadC treatment upregulates miR-375 level and represses HPV16 E6 expression

Proteomic analysis of cerebrospinal fluid from children with central nervous system tumors identifies candidate proteins relating to tumor metastatic spread

Hypermethylation of NDN promotes cell proliferation by activating the Wnt signaling pathway in colorectal cancer

Local immune response depends on p16^INK4a status of primary tumor in vulvar squamous cell carcinoma

Intensity-modulated radiotherapy provides better quality of life than two-dimensional conventional radiotherapy for patients with stage II nasopharyngeal carcinoma

Translational reprogramming of colorectal cancer cells induced by 5-fluorouracil through a miRNA-dependent mechanism

Soluble Axl is an accurate biomarker of cirrhosis and hepatocellular carcinoma development: results from a large scale multicenter analysis

STC1 promotes cell apoptosis via NF-κB phospho-P65 Ser536 in cervical cancer cells

Characterization of Sudan Ebolavirus infection in ferrets

Novel PPARα agonist MHY553 alleviates hepatic steatosis by increasing fatty acid oxidation and decreasing inflammation during aging

Association of RASgrf1 methylation with epileptic seizures

Synchronous splenectomy and hepatectomy for patients with small hepatocellular carcinoma and pathological spleen: neutrophil to lymphocyte ratio changes can predict the prognosis

MicroRNA-145 down-regulates mucin 5AC to alleviate airway remodeling and targets EGFR to inhibit cytokine expression

Depot-specific differences in fat mass expansion in WT and ob/ob mice

Efficacy and safety of neoadjuvant FOLFIRINOX for borderline resectable pancreatic adenocarcinoma: improved efficacy compared with gemcitabine-based regimen

PARP1 expression and its correlation with survival is tumour molecular subtype dependent in glioblastoma

Mitochondrial pyruvate carrier function determines cell stemness and metabolic reprogramming in cancer cells

Clinic characteristics of psoriasis in China: a nationwide survey in over 12000 patients

Evaluation and validation of the diagnostic value of the apparent diffusion coefficient for differentiating early-stage endometrial carcinomas from benign mimickers at 3T MRI

Identifying prognostic signature in ovarian cancer using DirGenerank

Prognostic significance of soluble mesothelin in malignant pleural mesothelioma: a meta-analysis

Evaluation of crescent formation as a predictive marker in immunoglobulin A nephropathy: a systematic review and meta-analysis

Duct-to-mucosa versus invagination pancreaticojejunostomy after pancreaticoduodenectomy: a meta-analysis

Relation of phosphodiesterase type 5 inhibitors and malignant melanoma: a meta-analysis and systematic review

APC hypermethylation for early diagnosis of colorectal cancer: a meta-analysis and literature review

The mutation of Trp64Arg in β3-adrenoreceptor-encoding gene is significantly associated with increased hypertension risk and elevated blood pressure: a meta-analysis

Feasibility and efficacy of simultaneous off-pump coronary artery bypass grafting and esophagectomy in elderly patients

Improvement of T stage precision by integration of surgical and pathological staging in radically resected stage pT3-pT4b gastric cancer

Clinicopathological features and prognosis of mesenteric gastrointestinal stromal tumor: evaluation of a pooled case series

Validation of different staging systems for hepatocellular carcinoma in a cohort of 249 patients undergoing radiotherapy

Relationship of thyroid function with intracranial arterial stenosis and carotid atheromatous plaques in ischemic stroke patients with euthyroidism

Clinical characteristics and improvement of the guideline-based management of acute myocardial infarction in China: a national retrospective analysis

Influence of delayed initiation of adjuvant chemotherapy on breast cancer survival is subtype-dependent

Axillary staging in breast cancer patients treated with neoadjuvant chemotherapy in two Dutch phase III studies

Lymphovascular invasion is a high risk factor for stage I/II colorectal cancer: a systematic review and meta-analysis

Lenalidomide and the risk of serious infection in patients with multiple myeloma: a systematic review and meta-analysis

Sentinel lymph node mapping in endometrial cancer: a systematic review and meta-analysis

Prognostic role of microRNAs in human gastrointestinal cancer: A systematic review and meta-analysis

Antiproliferative effect of somatostatin analogs in advanced gastro-entero-pancreatic neuroendocrine tumors: a systematic review and meta-analysis

Antimicrobial peptides with selective antitumor mechanisms: prospect for anticancer applications

Triple negative breast cancer: the kiss of death

Autophagy and mitophagy in the context of doxorubicin-induced cardiotoxicity

Association between the p.V37I variant of GJB2 and hearing loss: a pedigree and meta-analysis

Hypoxia inducible factors in hepatocellular carcinoma