Vol 8, No 12

Untangling ccRCC prognosis with SLINKY

The autophagy process

The rostromedial tegmental nucleus and alcohol addiction

The angiotensin receptor blocker, Losartan, inhibits mammary tumor development and progression to invasive carcinoma

Novel lincRNA SLINKY is a prognostic biomarker in kidney cancer

Quantification of HER2 and estrogen receptor heterogeneity in breast cancer by single-molecule RNA fluorescence in situ hybridization

Up-regulation of SERPINA3 correlates with high mortality of melanoma patients and increased migration and invasion of cancer cells

Expression and mutational analysis of c-CBL and its relationship to the MET receptor in head and neck squamous cell carcinoma

Personalized anticancer therapy selection using molecular landscape topology and thermodynamics

Diagnostic and prognostic value of serum periostin in patients with non-small cell lung cancer

Insights into the role and regulation of TCTP in skeletal muscle

Investigation on tissue specific effects of pro-apoptotic micro RNAs revealed miR-147b as a potential biomarker in ovarian cancer prognosis

Elevated neutrophil-to-lymphocyte ratio and monocyte-to-lymphocyte ratio and decreased platelet-to-lymphocyte ratio are associated with poor prognosis in multiple myeloma

Metformin and esophageal cancer risk in Taiwanese patients with type 2 diabetes mellitus

Digital PCR identifies changes in CDH1 (E-cadherin) transcription pattern in intestinal-type gastric cancer

MicroRNA-203 predicts human survival after resection of colorectal liver metastasis

Selenite inhibits glutamine metabolism and induces apoptosis by regulating GLS1 protein degradation via APC/C-CDH1 pathway in colorectal cancer cells

Co-ordinated overexpression of SIRT1 and STAT3 is associated with poor survival outcome in gastric cancer patients

B7-H4 promotes tumor growth and metastatic progression in lung cancer by impacting cell proliferation and survival

CBX6 overexpression contributes to tumor progression and is predictive of a poor prognosis in hepatocellular carcinoma

Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents

Identification of serum proteins and multivariate models for diagnosis and therapeutic monitoring of lung cancer

IL-17B activated mesenchymal stem cells enhance proliferation and migration of gastric cancer cells

Multiple functional SNPs in differentially expressed genes modify risk and survival of non-small cell lung cancer in Chinese female non-smokers

Glabridin attenuates lipopolysaccharide-induced acute lung injury by inhibiting p38MAPK/ERK signaling pathway

Prevalence and time trends of spina bifida in fourteen cities located in the Liaoning province of northeast China, 2006-2015

Therapy-induced developmental reprogramming of prostate cancer cells and acquired therapy resistance

Tumor volume increases the predictive accuracy of prognosis for gastric cancer: A retrospective cohort study of 3409 patients

Adamts18 deficiency promotes colon carcinogenesis by enhancing β-catenin and p38MAPK/ERK1/2 signaling in the mouse model of AOM/DSS-induced colitis-associated colorectal cancer

Fibulin-4 is associated with prognosis of endometrial cancer patients and inhibits cancer cell invasion and metastasis via Wnt/β-catenin signaling pathway

The expression of podoplanin protein is a diagnostic marker to distinguish the early infiltration of esophageal squamous cell carcinoma

The DNA repair function of CUX1 contributes to radioresistance

Pathological complete response of HER2-positive breast cancer to trastuzumab and chemotherapy can be predicted by HSD17B4 methylation

Long noncoding RNA MEG3, a potential novel biomarker to predict the clinical outcome of cancer patients: a meta-analysis

Sitagliptin may reduce prostate cancer risk in male patients with type 2 diabetes

High-efficacy targeting of colon-cancer liver metastasis with Salmonella typhimurium A1-R via intra-portal-vein injection in orthotopic nude-mouse models

Histone deacetylase inhibitors provoke a tumor supportive phenotype in pancreatic cancer associated fibroblasts

Structure-guided design of purine-based probes for selective Nek2 inhibition

A network meta-analysis of eight chemotherapy regimens for treatment of advanced ovarian cancer

Hyaluronan activates Hyal-2/WWOX/Smad4 signaling and causes bubbling cell death when the signaling complex is overexpressed

Identification of evolutionarily conserved DNA damage response genes that alter sensitivity to cisplatin

Analysis of miRNA profiles identified miR-196a as a crucial mediator of aberrant PI3K/AKT signaling in lung cancer cells

High OCT4A levels drive tumorigenicity and metastatic potential of medulloblastoma cells

High expression of GFAT1 predicts unfavorable prognosis in patients with hepatocellular carcinoma

Upregulation of FAM84B during prostate cancer progression

Meta-analysis of the effects of oral and intravenous dexamethasone premedication in the prevention of paclitaxel-induced allergic reactions

MicroRNA-101 inhibits proliferation, migration and invasion of human glioblastoma by targeting SOX9

Novel Epstein-Barr virus-like particles incorporating gH/gL-EBNA1 or gB-LMP2 induce high neutralizing antibody titers and EBV-specific T-cell responses in immunized mice

TM4SF1 promotes the self-renewal of esophageal cancer stem-like cells and is regulated by miR-141

Feedback circuitry via let-7c between lncRNA CCAT1 and c-Myc is involved in cigarette smoke extract-induced malignant transformation of HBE cells

Genetic variants in RhoA and ROCK1 genes are associated with the development, progression and prognosis of prostate cancer

Prognostic impact of immune microenvironment in laryngeal and pharyngeal squamous cell carcinoma: Immune cell subtypes, immuno-suppressive pathways and clinicopathologic characteristics

Secreted heat shock protein 90 promotes prostate cancer stem cell heterogeneity

HnRNP-L promotes prostate cancer progression by enhancing cell cycling and inhibiting apoptosis

Secreted GRP78 activates EGFR-SRC-STAT3 signaling and confers the resistance to sorafeinib in HCC cells

An association between autosomal-dominant polycystic kidney disease and the risk of acute myocardial infarction in Asian population — results of a nationwide study

Ochratoxin A induces ER stress and apoptosis in mesangial cells via a NADPH oxidase-derived reactive oxygen species-mediated calpain activation pathway

Gene expression changes in tumor free tongue tissue adjacent to tongue squamous cell carcinoma

Heparanase augments insulin receptor signaling in breast carcinoma

Inhibition of ALDH2 by O-GlcNAcylation contributes to the hyperglycemic exacerbation of myocardial ischemia/reperfusion injury

Proteome alterations associated with transformation of multiple myeloma to secondary plasma cell leukemia

Low serum paraoxonase1 activity levels predict coronary artery disease severity

MicroRNA-455-3p promotes invasion and migration in triple negative breast cancer by targeting tumor suppressor EI24

The clinical significance and underlying correlation of pStat-3 and integrin αvβ6 expression in gallbladder cancer

Targeting basal-like breast tumors with bromodomain and extraterminal domain (BET) and polo-like kinase inhibitors

Mitotic control of human papillomavirus genome-containing cells is regulated by the function of the PDZ-binding motif of the E6 oncoprotein

MiR-24 induces chemotherapy resistance and hypoxic advantage in breast cancer

A plasma metabolomic signature discloses human breast cancer

Long non-coding RNA ZFAS1 interacts with miR-150-5p to regulate Sp1 expression and ovarian cancer cell malignancy

MDM4 genetic variants and risk of gastric cancer in an Eastern Chinese population

Peripheral blood lymphocyte to monocyte ratio recovery from low levels at diagnosis after completion of first line therapy predicts good clinical outcomes in patients with diffuse large B-cell lymphoma

Reduced E-cadherin facilitates renal cell carcinoma progression by WNT/β-catenin signaling activation

Destructive effect of HIFU on rabbit embedded endometrial carcinoma tissues and their vascularities

Cancer-associated fibroblasts release exosomal microRNAs that dictate an aggressive phenotype in breast cancer

Identification of downstream metastasis-associated target genes regulated by LSD1 in colon cancer cells

Effect of chromatin structure on quantitative ultrasound parameters

Regulation of miRNA-29c and its downstream pathways in preneoplastic progression of triple-negative breast cancer

Methylation decreases the Bin1 tumor suppressor in ESCC and restoration by decitabine inhibits the epithelial mesenchymal transition

O-6-Methylguanine-DNA methyltransferase expression is associated with pituitary adenoma tumor recurrence: a systematic meta-analysis

A novel PHD-finger protein 14/KIF4A complex overexpressed in lung cancer is involved in cell mitosis regulation and tumorigenesis

Serum and tissue leptin in lung cancer: A meta-analysis

An association between overexpression of DNA methyltransferase 3B4 and clear cell renal cell carcinoma

miR-320a functions as a suppressor for gliomas by targeting SND1 and β-catenin, and predicts the prognosis of patients

Mitotic cell death induction by targeting the mitotic spindle with tubulin-inhibitory indole derivative molecules

Prognostic value of GLUT-1 expression in pancreatic cancer: results from 538 patients

CDCA2 promotes lung adenocarcinoma cell proliferation and predicts poor survival in lung adenocarcinoma patients

Melanoma-associated fibroblasts decrease tumor cell susceptibility to NK cell-mediated killing through matrix-metalloproteinases secretion

Long noncoding RNA HOTAIR promotes metastasis of renal cell carcinoma by up-regulating histone H3K27 demethylase JMJD3

Tumour-infiltrating regulatory T cell density before neoadjuvant chemoradiotherapy for rectal cancer does not predict treatment response

Maternal dietary zinc supplementation enhances the epigenetic-activated antioxidant ability of chick embryos from maternal normal and high temperatures

Clinicalpathological and prognostic significance of survivin expression in renal cell carcinoma: a meta-analysis

Apigenin inhibits renal cell carcinoma cell proliferation

HER inhibitor promotes BRAF/MEK inhibitor-induced redifferentiation in papillary thyroid cancer harboring BRAF^V600E

M2 microglia promotes neurogenesis and oligodendrogenesis from neural stem/progenitor cells via the PPARγ signaling pathway

MicroRNA-214 regulates smooth muscle cell differentiation from stem cells by targeting RNA-binding protein QKI

Harnessing RNA sequencing for global, unbiased evaluation of two new adjuvants for dendritic-cell immunotherapy

Baicalin promotes the bacteriostatic activity of lysozyme on S. aureus in mammary glands and neutrophilic granulocytes in mice

Early assessment of tumor response to photodynamic therapy using combined diffuse optical and diffuse correlation spectroscopy to predict treatment outcome

Whole-exome sequencing identified a homozygous BRDT mutation in a patient with acephalic spermatozoa

Does dual HER-2 blockade treatment increase the risk of severe toxicities of special interests in breast cancer patients: A meta-analysis of randomized controlled trials

CBX3 promotes colon cancer cell proliferation by CDK6 kinase-independent function during cell cycle

Rv2299c, a novel dendritic cell-activating antigen of Mycobacterium tuberculosis, fused-ESAT-6 subunit vaccine confers improved and durable protection against the hypervirulent strain HN878 in mice

eIF3i activity is critical for endothelial cells in tumor induced angiogenesis through regulating VEGFR and ERK translation

SNORA74B gene silencing inhibits gallbladder cancer cells by inducing PHLPP and suppressing Akt/mTOR signaling

PLCB4 copy gain and PLCß4 overexpression in primary gastrointestinal stromal tumors: Integrative characterization of a lipid-catabolizing enzyme associated with worse disease-free survival

The clinical use of the platelet/lymphocyte ratio and lymphocyte/monocyte ratio as prognostic predictors in colorectal cancer: a meta-analysis

Tissue transglutaminase induces Epithelial-Mesenchymal-Transition and the acquisition of stem cell like characteristics in colorectal cancer cells

Thymol mitigates lipopolysaccharide-induced endometritis by regulating the TLR4- and ROS-mediated NF-κB signaling pathways

Marriage is a dependent risk factor for mortality of colon adenocarcinoma without a time-varying effect

Role of caspases in CD95-induced biphasic activation of acid sphingomyelinase

EXOC3L2 rs597668 variant contributes to Alzheimer’s disease susceptibility in Asian population

HDAC8 functions in spindle assembly during mouse oocyte meiosis

Ring finger protein 6 promotes breast cancer cell proliferation by stabilizing estrogen receptor alpha

Cabozantinib targets bone microenvironment modulating human osteoclast and osteoblast functions

Suppression of microRNA-16 protects against acute myocardial infarction by reversing beta2-adrenergic receptor down-regulation in rats

miR-363-3p inhibits tumor growth by targeting PCNA in lung adenocarcinoma

Exosomal miR-940 maintains SRC-mediated oncogenic activity in cancer cells: a possible role for exosomal disposal of tumor suppressor miRNAs

HnRNPK/miR-223/FBXW7 feedback cascade promotes pancreatic cancer cell growth and invasion

Assessment of female breast dose for thoracic cone-beam CT using MOSFET dosimeters

Inhibition activity of a disulfide-stabilized diabody against basic fibroblast growth factor in lung cancer

Prognostic value of loss of heterozygosity and sub-cellular localization of SMAD4 varies with tumor stage in colorectal cancer

Platelet distribution width correlates with prognosis of gastric cancer

Benzyl isothiocyanate induces reactive oxygen species-initiated autophagy and apoptosis in human prostate cancer cells

Polymorphisms in human telomerase reverse transcriptase (hTERT) gene, gene- gene and gene-smoking interaction with susceptibility to gastric cancer in Chinese Han population

Insufficient hypothalamic angiotensin-converting enzyme 2 is associated with hypertension in SHR rats

The genetic variants in the PTEN/PI3K/AKT pathway predict susceptibility and CE(A)F chemotherapy response to breast cancer and clinical outcomes

Organ-specific isogenic metastatic breast cancer cell lines exhibit distinct Raman spectral signatures and metabolomes

The E3 ubiquitin ligase NEDD4 is translationally upregulated and facilitates pancreatic cancer

Epstein-Barr virus encoded microRNA BART7 regulates radiation sensitivity of nasopharyngeal carcinoma

Mitochondrial “power” drives tamoxifen resistance: NQO1 and GCLC are new therapeutic targets in breast cancer

Combined use of susceptibility weighted magnetic resonance imaging sequences and dynamic susceptibility contrast perfusion weighted imaging to improve the accuracy of the differential diagnosis of recurrence and radionecrosis in high-grade glioma patients

Impact of epidemiological characteristics of supratentorial gliomas in adults brought about by the 2016 world health organization classification of tumors of the central nervous system

A comparison of treatment modalities for nasal extranodal natural killer/T-cell lymphoma in early stages: The efficacy of CHOP regimen based concurrent chemoradiotherapy

Efficacy of intermittent pneumatic compression for venous thromboembolism prophylaxis in patients undergoing gynecologic surgery: A systematic review and meta-analysis

Bone marrow micro-environment is a crucial player for myelomagenesis and disease progression

Concurrent neoadjuvant chemoradiotherapy could improve survival outcomes for patients with esophageal cancer: a meta-analysis based on random clinical trials

The best strategy for HCC patients at each BCLC stage: a network meta-analysis of observational studies

Skeletal muscle aging: influence of oxidative stress and physical exercise

Efficacy of sequential therapies with sorafenib-sunitinib versus sunitinib-sorafenib in metastatic renal cell carcinoma: A systematic review and meta-analysis

Homeodomain-interacting protein kinase 2 (HIPK2): a promising target for anti-cancer therapies

Long non-coding RNAs in osteosarcoma

SPECT and PET radiopharmaceuticals for molecular imaging of apoptosis: from bench to clinic

Treatment of oral hyperpigmentation and gummy smile using lasers and role of plasma as a novel treatment technique in dentistry: An introductory review