Oncotarget

View Archive »

About The Cover

The cover for issue 12 of Oncotarget features Figure 5D, "Venn diagrams illustrate gene numbers upregulated (top) or downregulated (bottom) ≥1.25-fold following SLINKY and HNRNPK knockdown in each of two ccRCC cell lines," from Gong, et al.

Table of Contents

News

Why isn’t the angiotensin type 1 receptor a target in cancer

https://doi.org/10.18632/oncotarget.15682

Gavin P. Vinson
18618-18619
PDF  |  How to cite

Untangling ccRCC prognosis with SLINKY

https://doi.org/10.18632/oncotarget.15536

Bradley I. Reinfeld, and W. Kimryn Rathmell
18620-18621
PDF  |  How to cite

Editorial

Traumatic brain injury and hyperglycemia

https://doi.org/10.18632/oncotarget.15740

Daniel Vieira de Oliveira, Robson Luis Amorim, Rita de Cássia Almeida Vieira, and Wellingson Silva Paiva
18622-18622
Abstract  |  PDF  |  How to cite

The autophagy process

https://doi.org/10.18632/oncotarget.15951

Sushil Devkota
18623-18623
Abstract  |  PDF  |  How to cite

The rostromedial tegmental nucleus and alcohol addiction

https://doi.org/10.18632/oncotarget.15822

Jiang-Hong Ye, Rao Fu, and Wen He
18624-18625
Abstract  |  PDF  |  How to cite

Priority Research Papers

Stem cell cultures derived from pediatric brain tumors accurately model the originating tumors

https://doi.org/10.18632/oncotarget.14826

Anna Wenger, Susanna Larsson, Anna Danielsson, Kirstine Juul Elbæk, Petronella Kettunen, Magnus Tisell, Magnus Sabel, Birgitta Lannering, Claes Nordborg, Elizabeth Schepke, and Helena Carén
18626-18639
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The angiotensin receptor blocker Losartan inhibits mammary tumor development and progression to invasive carcinoma

https://doi.org/10.18632/oncotarget.15553

Rhiannon Coulson, Seng H. Liew, Angela A. Connelly, Nicholas S. Yee, Siddhartha Deb, Beena Kumar, Ana C. Vargas, Sandra A. O’Toole, Adam C. Parslow, Ashleigh Poh, Tracy Putoczki, Riley J. Morrow, Mariah Alorro, Kyren A. Lazarus, Evie F.W. Yeap, Kelly L. Walton, Craig A. Harrison, Natalie J. Hannan, Amee J. George, Colin D. Clyne, Matthias Ernst, Andrew M. Allen, and Ashwini L. Chand
18640-18656
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Novel lincRNA SLINKY is a prognostic biomarker in kidney cancer

https://doi.org/10.18632/oncotarget.15703

Xue Gong, Zurab Siprashvili, Okyaz Eminaga, Zhewei Shen, Yusuke Sato, Haruki Kume, Yukio Homma, Seishi Ogawa, Paul A. Khavari, Jonathan R. Pollack, and James D. Brooks
18657-18669
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Pathology

Angiogenesisrelated genes may be a more important factor than matrix metalloproteinases in bronchopulmonary dysplasia development

https://doi.org/10.18632/oncotarget.14722

Min Yang, Bo-Lin Chen, Jian-Bao Huang, Yan-Ni Meng, Xiao-Jun Duan, Lu Chen, Lin-Rui Li, and Yan-Ping Chen
18670-18679
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Quantification of HER2 and estrogen receptor heterogeneity in breast cancer by singlemolecule RNA fluorescence in situ hybridization

https://doi.org/10.18632/oncotarget.15727

Laura Annaratone, Michele Simonetti, Erik Wernersson, Caterina Marchiò, Silvano Garnerone, Maria Stella Scalzo, Magda Bienko, Roberto Chiarle, Anna Sapino, and Nicola Crosetto
18680-18698
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers

Association of coffee consumption with risk of colorectal cancer: a metaanalysis of prospective cohort studies

https://doi.org/10.18632/oncotarget.8627

Yong Gan, Jiang Wu, Shengchao Zhang, Liqing Li, Shiyi Cao, Naomie Mkandawire, Kun Ji, Chulani Herath, Chao Gao, Hong Xu, Yanfeng Zhou, Xingyue Song, Shanquan Chen, Yawen Chen, Tingting Yang, Jing Li, Yan Qiao, Sai Hu, Xiaoxv Yin, and Zuxun Lu
18699-18711
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Upregulation of SERPINA3 correlates with high mortality of melanoma patients and increased migration and invasion of cancer cells

https://doi.org/10.18632/oncotarget.9409

Jiaying Zhou, Yabin Cheng, Liren Tang, Magdalena Martinka, and Sunil Kalia
18712-18725
Abstract  |  PDF  |  Full Text  |  How to cite

Expression and mutational analysis of cCBL and its relationship to the MET receptor in head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.9640

Cleo E. Rolle, Yi-Hung Carol Tan, Tanguy Y. Seiwert, Sapana Vora, Rajani Kanteti, Rifat Hasina, George B. Carey, Mosmi Surati, Ralph R. Weichselbaum, Mark W. Lingen, Everett E. Vokes, and Ravi Salgia
18726-18734
Abstract  |  PDF  |  Full Text  |  How to cite

Personalized anticancer therapy selection using molecular landscape topology and thermodynamics

https://doi.org/10.18632/oncotarget.12932

Edward A. Rietman, Jacob G. Scott, Jack A. Tuszynski, and Giannoula Lakka Klement
18735-18745
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Diagnostic and prognostic value of serum periostin in patients with nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.13004

Chun-Hua Xu, Wei Wang, Yong Lin, Li-Hua Qian, Xiu-Wei Zhang, Qing-Bo Wang, and Li-Ke Yu
18746-18753
Abstract  |  PDF  |  Full Text  |  How to cite

Insights into the role and regulation of TCTP in skeletal muscle

https://doi.org/10.18632/oncotarget.13009

Craig A. Goodman, Allison M. Coenen, John W. Frey, Jae-Sung You, Robert G. Barker, Barnaby P. Frankish, Robyn M. Murphy, and Troy A. Hornberger
18754-18772
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Investigation on tissue specific effects of proapoptotic micro RNAs revealed miR147b as a potential biomarker in ovarian cancer prognosis

https://doi.org/10.18632/oncotarget.13095

Michael Kleemann, Jeremias Bereuther, Simon Fischer, Kim Marquart, Simon Hänle, Kristian Unger, Verena Jendrossek, Christian U. Riedel, René Handrick, and Kerstin Otte
18773-18791
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Elevated neutrophiltolymphocyte ratio and monocytetolymphocyte ratio and decreased platelettolymphocyte ratio are associated with poor prognosis in multiple myeloma

https://doi.org/10.18632/oncotarget.13320

Lihui Shi, Xiaoqi Qin, Huijun Wang, Yonghui Xia, Yuanyuan Li, Xuejing Chen, Lei Shang, Yu-Tzu Tai, Xiaoyan Feng, Prakrati Acharya, Chirag Acharya, Yan Xu, Shuhui Deng, Mu Hao, Dehui Zou, Yaozhong Zhao, Kun Ru, Lugui Qiu, and Gang An
18792-18801
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Metformin and esophageal cancer risk in Taiwanese patients with type 2 diabetes mellitus

https://doi.org/10.18632/oncotarget.13390

Chin-Hsiao Tseng
18802-18810
Abstract  |  PDF  |  Full Text  |  How to cite

Digital PCR identifies changes in CDH1 Ecadherin transcription pattern in intestinaltype gastric cancer

https://doi.org/10.18632/oncotarget.13401

Raefa Abou Khouzam, Chiara Molinari, Samanta Salvi, Monica Marabelli, Valeria Molinaro, Donata Orioli, Luca Saragoni, Paolo Morgagni, Daniele Calistri, and Guglielmina Nadia Ranzani
18811-18820
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MicroRNA203 predicts human survival after resection of colorectal liver metastasis

https://doi.org/10.18632/oncotarget.13816

T. Peter Kingham, Hoang C.B. Nguyen, Jian Zheng, Ioannis T. Konstantinidis, Eran Sadot, Jinru Shia, Deborah Kuk, Steven Zhang, Leonard Saltz, Michael I. D’Angelica, William R. Jarnagin, Hani Goodarzi, and Sohail F. Tavazoie
18821-18831
Abstract  |  PDF  |  Full Text  |  How to cite

Selenite inhibits glutamine metabolism and induces apoptosis by regulating GLS1 protein degradation via APC/CCDH1 pathway in colorectal cancer cells

https://doi.org/10.18632/oncotarget.13600

Junzhang Zhao, Rui Zhou, Kaiyuan Hui, Yang Yang, QiuYue Zhang, Yali Ci, Lei Shi, Caimin Xu, Fang Huang, and Yu Hu
18832-18847
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Coordinated overexpression of SIRT1 and STAT3 is associated with poor survival outcome in gastric cancer patients

https://doi.org/10.18632/oncotarget.14473

Shu Zhang, Shuling Huang, Chao Deng, Yu Cao, Jun Yang, Guangxia Chen, Bin Zhang, Chaoqin Duan, Jiong Shi, Bo Kong, Helmut Friess, Nanyi Zhao, Chen Huang, Xiaoli Huang, Lei Wang, and Xiaoping Zou
18848-18860
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

B7H4 promotes tumor growth and metastatic progression in lung cancer by impacting cell proliferation and survival

https://doi.org/10.18632/oncotarget.14475

Xiuqin Zhang, Liming Cai, Guangbo Zhang, Yu Shen, and Jianan Huang
18861-18871
Abstract  |  PDF  |  Full Text  |  How to cite

CBX6 overexpression contributes to tumor progression and is predictive of a poor prognosis in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.14770

Hao Zheng, Wei-hua Jiang, Tao Tian, Hai-song Tan, Ying Chen, Guang-lei Qiao, Jun Han, Sheng-yu Huang, Yuan Yang, Shuai Li, Zhen-guang Wang, Rong Gao, Hao Ren, Hao Xing, Jun-sheng Ni, Lin-Hui Wang, Li-jun Ma, and Wei-ping Zhou
18872-18884
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents

https://doi.org/10.18632/oncotarget.13806

Donghai Xiong, Jing Pan, Qi Zhang, Eva Szabo, Mark Steven Miller, Ronald A. Lubet, Ming You, and Yian Wang
18885-18900
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification of serum proteins and multivariate models for diagnosis and therapeutic monitoring of lung cancer

https://doi.org/10.18632/oncotarget.14782

Rong Ma, Heng Xu, Jianzhong Wu, Ashok Sharma, Shan Bai, Boying Dun, Changwen Jing, Haixia Cao, Zhuo Wang, Jin-Xiong She, and Jifeng Feng
18901-18913
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

IL17B activated mesenchymal stem cells enhance proliferation and migration of gastric cancer cells

https://doi.org/10.18632/oncotarget.14835

Qingli Bie, Bin Zhang, Caixia Sun, Xiaoyun Ji, Prince Amoah Barnie, Chen Qi, Jingjing Peng, Danyi Zhang, Dong Zheng, Zhaoliang Su, Shengjun Wang, and Huaxi Xu
18914-18923
Abstract  |  PDF  |  Full Text  |  How to cite

Multiple functional SNPs in differentially expressed genes modify risk and survival of nonsmall cell lung cancer in Chinese female nonsmokers

https://doi.org/10.18632/oncotarget.14836

Xue Fang, Zhihua Yin, Xuelian Li, Lingzi Xia, Xiaowei Quan, Yuxia Zhao, and Baosen Zhou
18924-18934
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Glabridin attenuates lipopolysaccharideinduced acute lung injury by inhibiting p38MAPK/ERK signaling pathway

https://doi.org/10.18632/oncotarget.14277

Li-peng Zhang, Yan Zhao, Guo-juan Liu, Da-gang Yang, Yi-huan Dong, and Li-hua Zhou
18935-18942
Abstract  |  PDF  |  Full Text  |  How to cite

Prevalence and time trends of spina bifida in fourteen cities located in the Liaoning province of northeast China 20062015

https://doi.org/10.18632/oncotarget.14848

Gen Ba, Qi-Jun Wu, Yan-Ling Chen, Yan-Hong Huang, and Ting-Ting Gong
18943-18948
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Therapyinduced developmental reprogramming of prostate cancer cells and acquired therapy resistance

https://doi.org/10.18632/oncotarget.14850

Mannan Nouri, Josselin Caradec, Amy Anne Lubik, Na Li, Brett G. Hollier, Mandeep Takhar, Manuel Altimirano-Dimas, Mengqian Chen, Mani Roshan-Moniri, Miriam Butler, Melanie Lehman, Jennifer Bishop, Sarah Truong, Shih-Chieh Huang, Dawn Cochrane, Michael Cox, Colin Collins, Martin Gleave, Nicholas Erho, Mohamed Alshalafa, Elai Davicioni, Colleen Nelson, Sheryl Gregory-Evans, R. Jeffrey Karnes, Robert B. Jenkins, Eric A. Klein, and Ralph Buttyan
18949-18967
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tumor volume increases the predictive accuracy of prognosis for gastric cancer: A retrospective cohort study of 3409 patients

https://doi.org/10.18632/oncotarget.14859

Zhen Liu, Peng Gao, Shushang Liu, Gaozan Zheng, Jianjun Yang, Li Sun, Liu Hong, Daiming Fan, Hongwei Zhang, and Fan Feng
18968-18978
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Adamts18 deficiency promotes colon carcinogenesis by enhancing βcatenin and p38MAPK/ERK1/2 signaling in the mouse model of AOM/DSSinduced colitisassociated colorectal cancer

https://doi.org/10.18632/oncotarget.14866

Tiantian Lu, Suying Dang, Rui Zhu, Ying Wang, Zongying Nie, Tao Hong, and Wei Zhang
18979-18990
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Fibulin4 is associated with prognosis of endometrial cancer patients and inhibits cancer cell invasion and metastasis via Wnt/βcatenin signaling pathway

https://doi.org/10.18632/oncotarget.15086

Tiantian Wang, Mei Wang, Shuang Fang, Qiang Wang, Rui Fang, and Jie Chen
18991-19012
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The expression of podoplanin protein is a diagnostic marker to distinguish the early infiltration of esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.14596

Guangyong Chen, Rui Xu, Bing Yue, Xue Mei, Peng Li, Xiaoge Zhou, Shoufang Huang, Liping Gong, and Shutian Zhang
19013-19020
Abstract  |  PDF  |  Full Text  |  How to cite

The DNA repair function of CUX1 contributes to radioresistance

https://doi.org/10.18632/oncotarget.14875

Zubaidah M. Ramdzan, Vasudeva Ginjala, Jordan B. Pinder, Dudley Chung, Caroline M. Donovan, Simran Kaur, Lam Leduy, Graham Dellaire, Shridar Ganesan, and Alain Nepveu
19021-19038
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Pathological complete response of HER2positive breast cancer to trastuzumab and chemotherapy can be predicted by HSD17B4 methylation

https://doi.org/10.18632/oncotarget.15118

Satoshi Fujii, Satoshi Yamashita, Takeshi Yamaguchi, Masato Takahashi, Yasuo Hozumi, Toshikazu Ushijima, and Hirofumi Mukai
19039-19048
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Long noncoding RNA MEG3 a potential novel biomarker to predict the clinical outcome of cancer patients: a metaanalysis

https://doi.org/10.18632/oncotarget.14987

Xiangrong Cui, Xuan Jing, Chunlan Long, Jie Tian, and Jing Zhu
19049-19056
Abstract  |  PDF  |  Full Text  |  How to cite

Sitagliptin may reduce prostate cancer risk in male patients with type 2 diabetes

https://doi.org/10.18632/oncotarget.12137

Chin-Hsiao Tseng
19057-19064
Abstract  |  PDF  |  Full Text  |  How to cite

Highefficacy targeting of coloncancer liver metastasis with Salmonella typhimurium A1R via intraportalvein injection in orthotopic nudemouse models

https://doi.org/10.18632/oncotarget.12227

Kei Kawaguchi, Takashi Murakami, Atushi Suetsugu, Tasuku Kiyuna, Kentaro Igarashi, Yukihiko Hiroshima, Ming Zhao, Yong Zhang, Michael Bouvet, Bryan M. Clary, Michiaki Unno, and Robert M. Hoffman
19065-19073
Abstract  |  PDF  |  Full Text  |  How to cite

Histone deacetylase inhibitors provoke a tumor supportive phenotype in pancreatic cancer associated fibroblasts

https://doi.org/10.18632/oncotarget.13572

Andrew H. Nguyen, Irmina A. Elliott, Nanping Wu, Cynthia Matsumura, Maria Vogelauer, Narsis Attar, Amanda Dann, Razmik Ghukasyan, Paul A. Toste, Sanjeet G. Patel, Jennifer L. Williams, Luyi Li, David W. Dawson, Caius Radu, Siavash K. Kurdistani, and Timothy R. Donahue
19074-19088
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Structureguided design of purinebased probes for selective Nek2 inhibition

https://doi.org/10.18632/oncotarget.13249

Christopher R. Coxon, Christopher Wong, Richard Bayliss, Kathy Boxall, Katherine H. Carr, Andrew M. Fry, Ian R. Hardcastle, Christopher J. Matheson, David R. Newell, Mangaleswaran Sivaprakasam, Huw Thomas, David Turner, Sharon Yeoh, Lan Z. Wang, Roger J. Griffin, Bernard T. Golding, and Céline Cano
19089-19124
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A network metaanalysis of eight chemotherapy regimens for treatment of advanced ovarian cancer

https://doi.org/10.18632/oncotarget.13253

Xi-Ping Jiang, Xiao-Hui Rui, Cai-Xia Guo, Ya-Qing Huang, Qin Li, and Yun Xu
19125-19136
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Hyaluronan activates Hyal2/WWOX/Smad4 signaling and causes bubbling cell death when the signaling complex is overexpressed

https://doi.org/10.18632/oncotarget.13268

Li-Jin Hsu, Qunying Hong, Shur-Tzu Chen, Hsiang-Lin Kuo, Lori Schultz, John Heath, Sing-Ru Lin, Ming-Hui Lee, Dong-Zhang Li, Zih-Ling Li, Hui-Ching Cheng, Gerard Armand, and Nan-Shan Chang
19137-19155
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification of evolutionarily conserved DNA damage response genes that alter sensitivity to cisplatin

https://doi.org/10.18632/oncotarget.13353

Anna V. Gaponova, Alexander Y. Deneka, Tim N. Beck, Hanqing Liu, Gregory Andrianov, Anna S. Nikonova, Emmanuelle Nicolas, Margret B. Einarson, Erica A. Golemis, and Ilya G. Serebriiskii
19156-19171
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Analysis of miRNA profiles identified miR196a as a crucial mediator of aberrant PI3K/AKT signaling in lung cancer cells

https://doi.org/10.18632/oncotarget.13432

Ilaria Guerriero, Daniela D'Angelo, Pierlorenzo Pallante, Mafalda Santos, Marianna Scrima, Donatella Malanga, Carmela De Marco, Maria Ravo, Alessandro Weisz, Carmelo Laudanna, Michele Ceccarelli, Geppino Falco, Antonia Rizzuto, and Giuseppe Viglietto
19172-19191
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

High OCT4A levels drive tumorigenicity and metastatic potential of medulloblastoma cells

https://doi.org/10.18632/oncotarget.15163

Patrícia Benites Gonçalves da Silva, Márcia Cristina Teixeira dos Santos, Carolina Oliveira Rodini, Carolini Kaid, Márcia Cristina Leite Pereira, Gabriela Furukawa, Daniel Sanzio Gimenes da Cruz, Mauricio Barbugiani Goldfeder, Clarissa Ribeiro Reily Rocha, Carla Rosenberg, and Oswaldo Keith Okamoto
19192-19204
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

High expression of GFAT1 predicts unfavorable prognosis in patients with hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.15164

Lili Li, Miaomiao Shao, Peike Peng, Caiting Yang, Shushu Song, Fangfang Duan, Dongwei Jia, Mingming Zhang, Junjie Zhao, Ran Zhao, Weicheng Wu, Lan Wang, Can Li, Hao Wu, Jie Zhang, Xin Wu, Yuanyuan Ruan, and Jianxin Gu
19205-19217
Abstract  |  PDF  |  Full Text  |  How to cite

Upregulation of FAM84B during prostate cancer progression

https://doi.org/10.18632/oncotarget.15168

Nicholas Wong, Yan Gu, Anil Kapoor, Xiaozeng Lin, Diane Ojo, Fengxiang Wei, Judy Yan, Jason de Melo, Pierre Major, Geoffrey Wood, Tariq Aziz, Jean-Claude Cutz, Michael Bonert, Arthur J. Patterson, and Damu Tang
19218-19235
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Metaanalysis of the effects of oral and intravenous dexamethasone premedication in the prevention of paclitaxelinduced allergic reactions

https://doi.org/10.18632/oncotarget.13705

Fu-chao Chen, Lin-hai Wang, Xiao-yu Zheng, Xiu-min Zhang, Jun Zhang, and Lin-Jun Li
19236-19243
Abstract  |  PDF  |  Full Text  |  How to cite

MicroRNA101 inhibits proliferation migration and invasion of human glioblastoma by targeting SOX9

https://doi.org/10.18632/oncotarget.13706

Nan Liu, Lei Zhang, Zhen Wang, Yingduan Cheng, Pengxing Zhang, Xin Wang, Weihong Wen, Hongwei Yang, Hui Liu, Weilin Jin, Yongsheng Zhang, and Yanyang Tu
19244-19254
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Novel EpsteinBarr viruslike particles incorporating gH/gLEBNA1 or gBLMP2 induce high neutralizing antibody titers and EBVspecific Tcell responses in immunized mice

https://doi.org/10.18632/oncotarget.13770

Elizabeth M. Perez, Joslyn Foley, Timelia Tison, Rute Silva, and Javier Gordon Ogembo
19255-19273
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

TM4SF1 promotes the selfrenewal of esophageal cancer stemlike cells and is regulated by miR141

https://doi.org/10.18632/oncotarget.13866

Lei Xue, Xiying Yu, Xingran Jiang, Xin Deng, Linlin Mao, Liping Guo, Jinhu Fan, Qinqxia Fan, Liuxing Wang, and Shih-Hsin Lu
19274-19284
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Feedback circuitry via let7c between lncRNA CCAT1 and cMyc is involved in cigarette smoke extractinduced malignant transformation of HBE cells

https://doi.org/10.18632/oncotarget.15195

Lu Lu, Hong Qi, Fei Luo, Hui Xu, Min Ling, Yu Qin, Ping Yang, Xinlu Liu, Qianlei Yang, Junchao Xue, Chao Chen, Jiachun Lu, Quanyong Xiang, Qizhan Liu, and Qian Bian
19285-19297
Abstract  |  PDF  |  Full Text  |  How to cite

Genetic variants in RhoA and ROCK1 genes are associated with the development progression and prognosis of prostate cancer

https://doi.org/10.18632/oncotarget.15197

Kang Liu, Xiao Li, Jie Wang, Yichun Wang, Huiyu Dong, and Jie Li
19298-19309
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prognostic impact of immune microenvironment in laryngeal and pharyngeal squamous cell carcinoma: Immune cell subtypes immunosuppressive pathways and clinicopathologic characteristics

https://doi.org/10.18632/oncotarget.14242

Georgia Karpathiou, Francois Casteillo, Jean-Baptiste Giroult, Fabien Forest, Pierre Fournel, Alessandra Monaya, Marios Froudarakis, Jean Marc Dumollard, Jean Michel Prades, and Michel Peoc'h
19310-19322
Abstract  |  PDF  |  Full Text  |  How to cite

Secreted heat shock protein 90 promotes prostate cancer stem cell heterogeneity

https://doi.org/10.18632/oncotarget.14252

Krystal D. Nolan, Jasmine Kaur, and Jennifer S. Isaacs
19323-19341
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

HnRNPL promotes prostate cancer progression by enhancing cell cycling and inhibiting apoptosis

https://doi.org/10.18632/oncotarget.14258

Xumin Zhou, Qi Li, Jincan He, Liren Zhong, Fangpeng Shu, Rongwei Xing, Daojun Lv, Bin Lei, Bo Wan, Yu Yang, Huayan Wu, Xiangming Mao, and Yaguang Zou
19342-19353
Abstract  |  PDF  |  Full Text  |  How to cite

Secreted GRP78 activates EGFRSRCSTAT3 signaling and confers the resistance to sorafeinib in HCC cells

https://doi.org/10.18632/oncotarget.15223

Rui Li, Gu Yanjiao, He Wubin, Wang Yue, Huang Jianhua, Zheng Huachuan, Su Rongjian, and Luan Zhidong
19354-19364
Abstract  |  PDF  |  Full Text  |  How to cite

An association between autosomaldominant polycystic kidney disease and the risk of acute myocardial infarction in Asian population — results of a nationwide study

https://doi.org/10.18632/oncotarget.14269

Pei-Hsun Sung, Hsin-Ju Chiang, Yao-Hsu Yang, Chi-Jen Chen, John Y. Chiang, and Hon-Kan Yip
19365-19375
Abstract  |  PDF  |  Full Text  |  How to cite

Ochratoxin A induces ER stress and apoptosis in mesangial cells via a NADPH oxidasederived reactive oxygen speciesmediated calpain activation pathway

https://doi.org/10.18632/oncotarget.14270

Meei-Ling Sheu, Chin-Chang Shen, Yuan-Siao Chen, and Chih-Kang Chiang
19376-19388
Abstract  |  PDF  |  Full Text  |  How to cite

Gene expression changes in tumor free tongue tissue adjacent to tongue squamous cell carcinoma

https://doi.org/10.18632/oncotarget.14288

Linda Boldrup, Xiaolian Gu, Philip J. Coates, Lena Norberg-Spaak, Robin Fahraeus, Göran Laurell, Torben Wilms, and Karin Nylander
19389-19402
Abstract  |  PDF  |  Full Text  |  How to cite

Heparanase augments insulin receptor signaling in breast carcinoma

https://doi.org/10.18632/oncotarget.14292

Rachel Goldberg, Amir Sonnenblick, Esther Hermano, Tamar Hamburger, Amichay Meirovitz, Tamar Peretz, and Michael Elkin
19403-19412
Abstract  |  PDF  |  Full Text  |  How to cite

Inhibition of ALDH2 by OGlcNAcylation contributes to the hyperglycemic exacerbation of myocardial ischemia/reperfusion injury

https://doi.org/10.18632/oncotarget.14297

Baoshan Liu, Jiali Wang, Minghua Li, Qiuhuan Yuan, Mengyang Xue, Feng Xu, and Yuguo Chen
19413-19426
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Proteome alterations associated with transformation of multiple myeloma to secondary plasma cell leukemia

https://doi.org/10.18632/oncotarget.14294

Alexey Zatula, Aida Dikic, Celine Mulder, Animesh Sharma, Cathrine B. Vågbø, Mirta M.L. Sousa, Anders Waage, and Geir Slupphaug
19427-19442
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Low serum paraoxonase1 activity levels predict coronary artery disease severity

https://doi.org/10.18632/oncotarget.14305

Ting Sun, Jingchao Hu, Zhaofang Yin, Zuojun Xu, Liang Zhang, Li Fan, Yang Zhuo, and Changqian Wang
19443-19454
Abstract  |  PDF  |  Full Text  |  How to cite

MicroRNA4553p promotes invasion and migration in triple negative breast cancer by targeting tumor suppressor EI24

https://doi.org/10.18632/oncotarget.14307

Zhishuang Li, Qingyong Meng, Aifeng Pan, Xiaojuan Wu, Jingjing Cui, Yan Wang, and Li Li
19455-19466
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The clinical significance and underlying correlation of pStat3 and integrin αvβ6 expression in gallbladder cancer

https://doi.org/10.18632/oncotarget.14444

Liu Enyu, Wang Na, Zhao Chuanzong, Wang Ben, Wu Xiaojuan, Wang Yan, Li Zequn, Hong Jianguo, Wang Jiayong, Liang Benjia, Peng Cheng, Zhu Min, and Zhang Zongli
19467-19477
Abstract  |  PDF  |  Full Text  |  How to cite

Targeting basallike breast tumors with bromodomain and extraterminal domain BET and pololike kinase inhibitors

https://doi.org/10.18632/oncotarget.14465

Cristina Nieto-Jiménez, Ana Alcaraz-Sanabria, Javier Pérez-Peña, Verónica Corrales-Sánchez, Gemma Serrano-Heras, Eva M. Galán-Moya, Leticia Serrano-Oviedo, Juan Carlos Montero, Miguel Burgos, Juan Llopis, Atanasio Pandiella, and Alberto Ocaña
19478-19490
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Mitotic control of human papillomavirus genomecontaining cells is regulated by the function of the PDZbinding motif of the E6 oncoprotein

https://doi.org/10.18632/oncotarget.14469

Elizabeth K. Marsh, Craig P. Delury, Nicholas J. Davies, Christopher J. Weston, Mohammed A.L. Miah, Lawrence Banks, Joanna L. Parish, Martin R. Higgs, and Sally Roberts
19491-19506
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR24 induces chemotherapy resistance and hypoxic advantage in breast cancer

https://doi.org/10.18632/oncotarget.14470

Giuseppina Roscigno, Ilaria Puoti, Immacolata Giordano, Elvira Donnarumma, Valentina Russo, Alessandra Affinito, Assunta Adamo, Cristina Quintavalle, Matilde Todaro, Maria dM Vivanco, and Gerolama Condorelli
19507-19521
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A plasma metabolomic signature discloses human breast cancer

https://doi.org/10.18632/oncotarget.14521

Mariona Jové, Ricardo Collado, José Luís Quiles, Mari-Carmen Ramírez-Tortosa, Joaquim Sol, Maria Ruiz-Sanjuan, Mónica Fernandez, Capilla de la Torre Cabrera, Cesar Ramírez-Tortosa, Sergio Granados-Principal, Pedro Sánchez-Rovira, and Reinald Pamplona
19522-19533
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Long noncoding RNA ZFAS1 interacts with miR1505p to regulate Sp1 expression and ovarian cancer cell malignancy

https://doi.org/10.18632/oncotarget.14663

Bairong Xia, Yan Hou, Hong Chen, Shanshan Yang, Tianbo Liu, Mei Lin, and Ge Lou
19534-19546
Abstract  |  PDF  |  Full Text  |  How to cite

MDM4 genetic variants and risk of gastric cancer in an Eastern Chinese population

https://doi.org/10.18632/oncotarget.14666

Meng-Yun Wang, Ming Jia, Jing He, Fei Zhou, Li-Xin Qiu, Meng-Hong Sun, Ya-Jun Yang, Jiu-Cun Wang, Li Jin, Ya-Nong Wang, and Qing-Yi Wei
19547-19555
Abstract  |  PDF  |  Full Text  |  How to cite

Peripheral blood lymphocyte to monocyte ratio recovery from low levels at diagnosis after completion of first line therapy predicts good clinical outcomes in patients with diffuse large Bcell lymphoma

https://doi.org/10.18632/oncotarget.14700

Shujuan Zhou, Linglong Xu, Yongyong Ma, Liyuan Tang, Yu Zhang, Yifen Shi, Lan Sun, Yi Chen, Bin Liang, Yuhong Zhou, Kang Yu, and Jianping Shen
19556-19565
Abstract  |  PDF  |  Full Text  |  How to cite

Reduced Ecadherin facilitates renal cell carcinoma progression by WNT/βcatenin signaling activation

https://doi.org/10.18632/oncotarget.15361

Xinqi Zhang, Mingxi Yang, Hua Shi, Jianxin Hu, Yuanlin Wang, Zhaolin Sun, and Shuxiong Xu
19566-19576
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Destructive effect of HIFU on rabbit embedded endometrial carcinoma tissues and their vascularities

https://doi.org/10.18632/oncotarget.14751

Liming Guan, and Gang Xu
19577-19591
Abstract  |  PDF  |  Full Text  |  How to cite

Cancerassociated fibroblasts release exosomal microRNAs that dictate an aggressive phenotype in breast cancer

https://doi.org/10.18632/oncotarget.14752

Elvira Donnarumma, Danilo Fiore, Martina Nappa, Giuseppina Roscigno, Assunta Adamo, Margherita Iaboni, Valentina Russo, Alessandra Affinito, Ilaria Puoti, Cristina Quintavalle, Anna Rienzo, Salvatore Piscuoglio, Renato Thomas, and Gerolama Condorelli
19592-19608
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification of downstream metastasisassociated target genes regulated by LSD1 in colon cancer cells

https://doi.org/10.18632/oncotarget.14778

Jiang Chen, Jie Ding, Ziwei Wang, Jian Zhu, Xuejian Wang, and Jiyi Du
19609-19630
Abstract  |  PDF  |  Full Text  |  How to cite

Effect of chromatin structure on quantitative ultrasound parameters

https://doi.org/10.18632/oncotarget.14816

Maurice Pasternak, Lilian Doss, Golnaz Farhat, Azza Al-Mahrouki, Christina Hyunjung Kim, Michael Kolios, William Tyler Tran, and Gregory J. Czarnota
19631-19644
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Regulation of miRNA29c and its downstream pathways in preneoplastic progression of triplenegative breast cancer

https://doi.org/10.18632/oncotarget.14902

Anjana Bhardwaj, Harpreet Singh, Kimal Rajapakshe, Kazunoshin Tachibana, Nivetha Ganesan, Yinghong Pan, Preethi H. Gunaratne, Cristian Coarfa, and Isabelle Bedrosian
19645-19660
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Methylation decreases the Bin1 tumor suppressor in ESCC and restoration by decitabine inhibits the epithelial mesenchymal transition

https://doi.org/10.18632/oncotarget.14914

Xuexiao Wang, Jiali Wang, Yunlong Jia, Yu Wang, Xiaonan Han, Yuqing Duan, Wei Lv, Ming Ma, and Lihua Liu
19661-19673
Abstract  |  PDF  |  Full Text  |  How to cite

O6MethylguanineDNA methyltransferase expression is associated with pituitary adenoma tumor recurrence: a systematic metaanalysis

https://doi.org/10.18632/oncotarget.14936

Congxin Dai, Bowen Sun, Xiaohai Liu, Xinjie Bao, Ming Feng, Yong Yao, Junji Wei, Kan Deng, Chengxian Yang, Xueyuan Li, Wenbin Ma, and Renzhi Wang
19674-19683
Abstract  |  PDF  |  Full Text  |  How to cite

A novel PHDfinger protein 14/KIF4A complex overexpressed in lung cancer is involved in cell mitosis regulation and tumorigenesis

https://doi.org/10.18632/oncotarget.14962

Lin Zhang, Qin Huang, Jiatao Lou, Liangjian Zou, Yiguo Wang, Peng Zhang, Guang Yang, Junyi Zhang, Lan Yu, Dai Yan, Chenyi Zhang, Jing Qiao, Shuting Wang, Sai Wang, Yongdong Xu, Hongbin Ji, Zhengjun Chen, and Zhe Zhang
19684-19698
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Serum and tissue leptin in lung cancer: A metaanalysis

https://doi.org/10.18632/oncotarget.14963

Xiang Tong, Yao Ma, Qilong Zhou, Jie He, Bo Peng, Sitong Liu, Zhipeng Yan, Xin Yang, and Hong Fan
19699-19711
Abstract  |  PDF  |  Full Text  |  How to cite

An association between overexpression of DNA methyltransferase 3B4 and clear cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.14966

You Liu, Liantao Sun, Peter Fong, Jie Yang, Zhuxia Zhang, Shuihui Yin, Shuyuan Jiang, Xiaolei Liu, Hongge Ju, Lihua Huang, Jing Bai, Kerui Gong, Shaochun Yan, Chunyang Zhang, and Guo Shao
19712-19722
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miR320a functions as a suppressor for gliomas by targeting SND1 and βcatenin and predicts the prognosis of patients

https://doi.org/10.18632/oncotarget.14975

Huining Li, Lin Yu, Jing Liu, Xiuwu Bian, Cuijuan Shi, Cuiyun Sun, Xuexia Zhou, Yanjun Wen, Dan Hua, Shujun Zhao, Linlin Ren, Tongling An, Wenjun Luo, Qian Wang, and Shizhu Yu
19723-19737
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Mitotic cell death induction by targeting the mitotic spindle with tubulininhibitory indole derivative molecules

https://doi.org/10.18632/oncotarget.14980

Erica Di Cesare, Annalisa Verrico, Andrea Miele, Maria Giubettini, Paola Rovella, Antonio Coluccia, Valeria Famiglini, Giuseppe La Regina, Enrico Cundari, Romano Silvestri, and Patrizia Lavia
19738-19759
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prognostic value of GLUT1 expression in pancreatic cancer: results from 538 patients

https://doi.org/10.18632/oncotarget.15035

Gaowa Sharen, Yaojun Peng, Haidong Cheng, Yang Liu, Yonghong Shi, and Jian Zhao
19760-19767
Abstract  |  PDF  |  Full Text  |  How to cite

CDCA2 promotes lung adenocarcinoma cell proliferation and predicts poor survival in lung adenocarcinoma patients

https://doi.org/10.18632/oncotarget.15519

Run Shi, Chunrong Zhang, Yaqin Wu, Xin Wang, Qi Sun, Jing Sun, Wenjie Xia, Gaochao Dong, Anpeng Wang, Feng Jiang, and Lin Xu
19768-19779
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Melanomaassociated fibroblasts decrease tumor cell susceptibility to NK cellmediated killing through matrixmetalloproteinases secretion

https://doi.org/10.18632/oncotarget.15540

Linda Ziani, Thouraya Ben Safta-Saadoun, Johanne Gourbeix, Andrea Cavalcanti, Caroline Robert, Gilles Favre, Salem Chouaib, and Jerome Thiery
19780-19794
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Long noncoding RNA HOTAIR promotes metastasis of renal cell carcinoma by upregulating histone H3K27 demethylase JMJD3

https://doi.org/10.18632/oncotarget.15047

Ming Xia, Lv Yao, Qiaoxia Zhang, Feng Wang, Hongbin Mei, Xiaoqiang Guo, and Weiren Huang
19795-19802
Abstract  |  PDF  |  Full Text  |  How to cite

Tumourinfiltrating regulatory T cell density before neoadjuvant chemoradiotherapy for rectal cancer does not predict treatment response

https://doi.org/10.18632/oncotarget.15048

Melanie J. McCoy, Chris Hemmings, Chidozie C. Anyaegbu, Stephanie J. Austin, Tracey F. Lee-Pullen, Timothy J. Miller, Max K. Bulsara, Nikolajs Zeps, Anna K. Nowak, Richard A. Lake, and Cameron F. Platell
19803-19813
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Maternal dietary zinc supplementation enhances the epigeneticactivated antioxidant ability of chick embryos from maternal normal and high temperatures

https://doi.org/10.18632/oncotarget.15057

Yongwen Zhu, Xiudong Liao, Lin Lu, Wenxiang Li, Liyang Zhang, Cheng Ji, Xi Lin, Hsiao-Ching Liu, Jack Odle, and Xugang Luo
19814-19824
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinicalpathological and prognostic significance of survivin expression in renal cell carcinoma: a metaanalysis

https://doi.org/10.18632/oncotarget.15082

Zhichen Pu, Guang-Zhen Wu, and QiFei Wang
19825-19833
Abstract  |  PDF  |  Full Text  |  How to cite

Apigenin inhibits renal cell carcinoma cell proliferation

https://doi.org/10.18632/oncotarget.15771

Shuai Meng, Yi Zhu, Jiang-Feng Li, Xiao Wang, Zhen Liang, Shi-Qi Li, Xin Xu, Hong Chen, Ben Liu, Xiang-Yi Zheng, and Li-Ping Xie
19834-19842
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

HER inhibitor promotes BRAF/MEK inhibitorinduced redifferentiation in papillary thyroid cancer harboring BRAFV600E

https://doi.org/10.18632/oncotarget.15773

Lingxiao Cheng, Yuchen Jin, Min Liu, Maomei Ruan, and Libo Chen
19843-19854
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

M2 microglia promotes neurogenesis and oligodendrogenesis from neural stem/progenitor cells via the PPARγ signaling pathway

https://doi.org/10.18632/oncotarget.15774

Jichao Yuan, Hongfei Ge, Wei Liu, Haitao Zhu, Yaxing Chen, Xuan Zhang, Yang Yang, Yi Yin, Weixiang Chen, Wanjiang Wu, Yunfeng Yang, and Jiangkai Lin
19855-19865
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MicroRNA214 regulates smooth muscle cell differentiation from stem cells by targeting RNAbinding protein QKI

https://doi.org/10.18632/oncotarget.15189

Yutao Wu, Zhoubin Li, Mei Yang, Bing Dai, Feng Hu, Feng Yang, Jianhua Zhu, Ting Chen, and Li Zhang
19866-19878
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Harnessing RNA sequencing for global unbiased evaluation of two new adjuvants for dendriticcell immunotherapy

https://doi.org/10.18632/oncotarget.15190

Till S.M. Mathan, Johannes Textor, Annette E. Sköld, Inge Reinieren-Beeren, Tom van Oorschot, Mareke Brüning, Carl G. Figdor, Sonja I. Buschow, Ghaith Bakdash, and I. Jolanda M. de Vries
19879-19893
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Baicalin promotes the bacteriostatic activity of lysozyme on S aureus in mammary glands and neutrophilic granulocytes in mice

https://doi.org/10.18632/oncotarget.15193

Xuejiao Gao, Mengyao Guo, Zecai Zhang, Peng Shen, Zhengtao Yang, and Naisheng Zhang
19894-19901
Abstract  |  PDF  |  Full Text  |  How to cite

Early assessment of tumor response to photodynamic therapy using combined diffuse optical and diffuse correlation spectroscopy to predict treatment outcome

https://doi.org/10.18632/oncotarget.15720

Patricia Thong, Kijoon Lee, Hui-Jin Toh, Jing Dong, Chuan-Sia Tee, Kar-Perng Low, Pui-Haan Chang, Ramaswamy Bhuvaneswari, Ngian-Chye Tan, and Khee-Chee Soo
19902-19913
Abstract  |  PDF  |  Full Text  |  How to cite

Wholeexome sequencing identified a homozygous BRDT mutation in a patient with acephalic spermatozoa

https://doi.org/10.18632/oncotarget.15251

Lin Li, Yanwei Sha, Xi Wang, Ping Li, Jing Wang, Kehkooi Kee, and Binbin Wang
19914-19922
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Does dual HER2 blockade treatment increase the risk of severe toxicities of special interests in breast cancer patients: A metaanalysis of randomized controlled trials

https://doi.org/10.18632/oncotarget.15252

Shuai Hao, Wuguo Tian, Bo Gao, Yan Jiang, Xiaohua Zhang, Shu Zhang, Lingji Guo, Jianjie Zhao, Gang Zhang, Chunyan Hu, Jie Yan, and Donglin Luo
19923-19933
Abstract  |  PDF  |  Full Text  |  How to cite

CBX3 promotes colon cancer cell proliferation by CDK6 kinaseindependent function during cell cycle

https://doi.org/10.18632/oncotarget.15253

Yao Fan, Haiping Li, Xiaolong Liang, and Zheng Xiang
19934-19946
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Rv2299c a novel dendritic cellactivating antigen of Mycobacterium tuberculosis fusedESAT6 subunit vaccine confers improved and durable protection against the hypervirulent strain HN878 in mice

https://doi.org/10.18632/oncotarget.15256

Han-Gyu Choi, Seunga Choi, Yong Woo Back, Seungwha Paik, Hye-Soo Park, Woo Sik Kim, Hongmin Kim, Seung Bin Cha, Chul Hee Choi, Sung Jae Shin, and Hwa-Jung Kim
19947-19967
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

eIF3i activity is critical for endothelial cells in tumor induced angiogenesis through regulating VEGFR and ERK translation

https://doi.org/10.18632/oncotarget.15274

Yaguang Zhang, Ping Wang, Qian Zhang, Xiaomin Yao, Linjie Zhao, Yibin Liu, Xiaowei Liu, Rui Tao, Chuan Yu, Yuhao Li, Xiangrong Song, and Shaohua Yao
19968-19979
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

SNORA74B gene silencing inhibits gallbladder cancer cells by inducing PHLPP and suppressing Akt/mTOR signaling

https://doi.org/10.18632/oncotarget.15301

Yiyu Qin, Li Meng, Yang Fu, Zhiwei Quan, Mingzhe Ma, Mingzhe Weng, Zhengdong Zhang, Cuixiang Gao, Xinghua Shi, and Koulan Han
19980-19996
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PLCB4 copy gain and PLCß4 overexpression in primary gastrointestinal stromal tumors: Integrative characterization of a lipidcatabolizing enzyme associated with worse diseasefree survival

https://doi.org/10.18632/oncotarget.15306

Chien-Feng Li, Ting-Ting Liu, I-Chieh Chuang, Yen-Yang Chen, Fu-Min Fang, Ti-Chun Chan, Wan-Shan Li, and Hsuan-Ying Huang
19997-20010
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The clinical use of the platelet/lymphocyte ratio and lymphocyte/monocyte ratio as prognostic predictors in colorectal cancer: a metaanalysis

https://doi.org/10.18632/oncotarget.15311

Ya-Huan Guo, Hai-Feng Sun, Yan-Bing Zhang, Zi-Jun Liao, Lei Zhao, Jie Cui, Tao Wu, Jian-Rong Lu, Ke-Jun Nan, and Shu-Hong Wang
20011-20024
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tissue transglutaminase induces EpithelialMesenchymalTransition and the acquisition of stem cell like characteristics in colorectal cancer cells

https://doi.org/10.18632/oncotarget.15370

Oluseyi Ayinde, Zhuo Wang, and Martin Griffin
20025-20041
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Thymol mitigates lipopolysaccharideinduced endometritis by regulating the TLR4 and ROSmediated NFκB signaling pathways

https://doi.org/10.18632/oncotarget.15373

Haichong Wu, Kangfeng Jiang, Nannan Yin, Xiaofei Ma, Gan Zhao, Changwei Qiu, and Ganzhen Deng
20042-20055
Abstract  |  PDF  |  Full Text  |  How to cite

Marriage is a dependent risk factor for mortality of colon adenocarcinoma without a timevarying effect

https://doi.org/10.18632/oncotarget.15378

Minling Liu, Lixian Li, Wei Yu, Jie Chen, Weibin Xiong, Shuang Chen, and Li Yu
20056-20066
Abstract  |  PDF  |  Full Text  |  How to cite

Role of caspases in CD95induced biphasic activation of acid sphingomyelinase

https://doi.org/10.18632/oncotarget.15379

Mario Stephan, Bärbel Edelmann, Supandi Winoto-Morbach, Ottmar Janssen, Uwe Bertsch, Cristiana Perrotta, Stefan Schütze, and Jürgen Fritsch
20067-20085
Abstract  |  PDF  |  Full Text  |  How to cite

EXOC3L2 rs597668 variant contributes to Alzheimer’s disease susceptibility in Asian population

https://doi.org/10.18632/oncotarget.15380

Qing-jian Wu, Shu-yin Sun, Cheng-jun Yan, Zi-cui Cheng, Ming-feng Yang, Zi-fei Li, Hou-wen Cheng, and Ti-kun Fang
20086-20091
Abstract  |  PDF  |  Full Text  |  How to cite

HDAC8 functions in spindle assembly during mouse oocyte meiosis

https://doi.org/10.18632/oncotarget.15383

Kemei Zhang, Yajuan Lu, Chaohua Jiang, Wei Liu, Jing Shu, Xueqin Chen, Yingjiao Shi, Ensheng Wang, Li Wang, Qinbo Hu, Yibo Dai, and Bo Xiong
20092-20102
Abstract  |  PDF  |  Full Text  |  How to cite

Ring finger protein 6 promotes breast cancer cell proliferation by stabilizing estrogen receptor alpha

https://doi.org/10.18632/oncotarget.15384

Yuanying Zeng, Xin Xu, Siyu Wang, Zubin Zhang, Yan Liu, Kunkun Han, Biyin Cao, and Xinliang Mao
20103-20112
Abstract  |  PDF  |  Full Text  |  How to cite

Cabozantinib targets bone microenvironment modulating human osteoclast and osteoblast functions

https://doi.org/10.18632/oncotarget.15390

Marco Fioramonti, Daniele Santini, Michele Iuliani, Giulia Ribelli, Paolo Manca, Nicola Papapietro, Filippo Spiezia, Bruno Vincenzi, Vincenzo Denaro, Antonio Russo, Giuseppe Tonini, and Francesco Pantano
20113-20121
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Suppression of microRNA16 protects against acute myocardial infarction by reversing beta2adrenergic receptor downregulation in rats

https://doi.org/10.18632/oncotarget.15391

Jiaqi Liu, Fei Sun, Yuying Wang, Wanqi Yang, Hongwen Xiao, Yue Zhang, Renzhong Lu, Haixia Zhu, Yuting Zhuang, Zhenwei Pan, Zhiguo Wang, Zhimin Du, and Yanjie Lu
20122-20132
Abstract  |  PDF  |  Full Text  |  How to cite

miR3633p inhibits tumor growth by targeting PCNA in lung adenocarcinoma

https://doi.org/10.18632/oncotarget.15448

Yahong Wang, Ting Chen, Haili Huang, Yun Jiang, Lawei Yang, Ziying Lin, Huijuan He, Tie Liu, Bin Wu, Jie Chen, David W. Kamp, and Gang Liu
20133-20144
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Exosomal miR940 maintains SRCmediated oncogenic activity in cancer cells: a possible role for exosomal disposal of tumor suppressor miRNAs

https://doi.org/10.18632/oncotarget.15525

Mohammed H. Rashed, Pinar Kanlikilicer, Cristian Rodriguez-Aguayo, Martin Pichler, Recep Bayraktar, Emine Bayraktar, Cristina Ivan, Justyna Filant, Andreia Silva, Burcu Aslan, Merve Denizli, Rahul Mitra, Bulent Ozpolat, George A. Calin, Anil K. Sood, Mohamed F. Abd-Ellah, Gouda K. Helal, and Gabriel Lopez Berestein
20145-20164
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

HnRNPK/miR223/FBXW7 feedback cascade promotes pancreatic cancer cell growth and invasion

https://doi.org/10.18632/oncotarget.15529

De He, Cheng Huang, Qingxin Zhou, Dawei Liu, Longhui Xiong, Hongxia Xiang, Guangnian Ma, and Zhiyong Zhang
20165-20178
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Assessment of female breast dose for thoracic conebeam CT using MOSFET dosimeters

https://doi.org/10.18632/oncotarget.15555

Wenzhao Sun, Bin Wang, Bo Qiu, Jian Liang, Weihao Xie, Xiaowu Deng, and Zhenyu Qi
20179-20186
Abstract  |  PDF  |  Full Text  |  How to cite

Inhibition activity of a disulfidestabilized diabody against basic fibroblast growth factor in lung cancer

https://doi.org/10.18632/oncotarget.15556

Yaxiong Cai, Shuange Yao, Jiangchuan Zhong, Jinxia Zhang, Haowu Jiang, Yanrui Deng, and Ning Deng
20187-20197
Abstract  |  PDF  |  Full Text  |  How to cite

Prognostic value of loss of heterozygosity and subcellular localization of SMAD4 varies with tumor stage in colorectal cancer

https://doi.org/10.18632/oncotarget.15560

Xu Jia, Chandrakumar Shanmugam, Ravi K. Paluri, Nirag C. Jhala, Michael P. Behring, Venkat R. Katkoori, Shajan P. Sugandha, Sejong Bae, Temesgen Samuel, and Upender Manne
20198-20212
Abstract  |  PDF  |  Full Text  |  How to cite

Platelet distribution width correlates with prognosis of gastric cancer

https://doi.org/10.18632/oncotarget.15561

Xin Zhang, Ming-ming Cui, Shuang Fu, Lu-lu Li, Yan-song Liu, Zhi-ping Liu, Tiemin Liu, Rui-tao Wang, and Kai-jiang Yu
20213-20219
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Benzyl isothiocyanate induces reactive oxygen speciesinitiated autophagy and apoptosis in human prostate cancer cells

https://doi.org/10.18632/oncotarget.15643

Ji-Fan Lin, Te-Fu Tsai, Shan-Che Yang, Yi-Chia Lin, Hung-En Chen, Kuang-Yu Chou, and Thomas I-Sheng Hwang
20220-20234
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Polymorphisms in human telomerase reverse transcriptase hTERT gene gene gene and genesmoking interaction with susceptibility to gastric cancer in Chinese Han population

https://doi.org/10.18632/oncotarget.15664

Jian Zhang, Hui Ju, Jun- Ru Gao, Xue-Long Jiao, and Yun Lu
20235-20243
Abstract  |  PDF  |  Full Text  |  How to cite

Insufficient hypothalamic angiotensinconverting enzyme 2 is associated with hypertension in SHR rats

https://doi.org/10.18632/oncotarget.15666

Kun Wang, Yuanyuan Xu, Weiwei Yang, and Yuanshu Zhang
20244-20251
Abstract  |  PDF  |  Full Text  |  How to cite

The genetic variants in the PTEN/PI3K/AKT pathway predict susceptibility and CEAF chemotherapy response to breast cancer and clinical outcomes

https://doi.org/10.18632/oncotarget.15690

Xiang Li, Ruishan Zhang, Zhuangkai Liu, Shuang Li, and Hong Xu
20252-20265
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Organspecific isogenic metastatic breast cancer cell lines exhibit distinct Raman spectral signatures and metabolomes

https://doi.org/10.18632/oncotarget.14865

Paul T. Winnard Jr., Chi Zhang, Farhad Vesuna, Jeon Woong Kang, Jonah Garry, Ramachandra Rao Dasari, Ishan Barman, and Venu Raman
20266-20287
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The E3 ubiquitin ligase NEDD4 is translationally upregulated and facilitates pancreatic cancer

https://doi.org/10.18632/oncotarget.15446

Min Weng, Zhu-Lin Luo, Xiao-Ling Wu, and Wei-Zheng Zeng
20288-20296
Abstract  |  PDF  |  Full Text  |  How to cite

EpsteinBarr virus encoded microRNA BART7 regulates radiation sensitivity of nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.15526

Wei Gao, Zeng-Hong Li, Siqi Chen, Jimmy Yu-Wai Chan, Min Yin, Min-Juan Zhang, and Thian-Sze Wong
20297-20308
Abstract  |  PDF  |  Full Text  |  How to cite

Mitochondrial “power” drives tamoxifen resistance: NQO1 and GCLC are new therapeutic targets in breast cancer

https://doi.org/10.18632/oncotarget.15852

Marco Fiorillo, Federica Sotgia, Diego Sisci, Anna Rita Cappello, and Michael P. Lisanti
20309-20327
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinical Research Papers

CXC chemokine receptor 1 predicts postoperative prognosis and chemotherapeutic benefits for TNM II and III resectable gastric cancer patients

https://doi.org/10.18632/oncotarget.12815

Yifan Cao, Hao Liu, Heng Zhang, Chao Lin, Ruochen Li, Songyang Wu, He Li, Hongyong He, Weijuan Zhang, and Jiejie Xu
20328-20339
Abstract  |  PDF  |  Full Text  |  How to cite

Combined use of susceptibility weighted magnetic resonance imaging sequences and dynamic susceptibility contrast perfusion weighted imaging to improve the accuracy of the differential diagnosis of recurrence and radionecrosis in highgrade glioma patients

https://doi.org/10.18632/oncotarget.13050

Tae-Hyung Kim, Tae Jin Yun, Chul-Kee Park, Tae Min Kim, Ji-Hoon Kim, Chul-Ho Sohn, Jae Kyung Won, Sung-Hye Park, Il Han Kim, and Seung Hong Choi
20340-20353
Abstract  |  PDF  |  Full Text  |  How to cite

Impact of epidemiological characteristics of supratentorial gliomas in adults brought about by the 2016 world health organization classification of tumors of the central nervous system

https://doi.org/10.18632/oncotarget.13555

Haihui Jiang, Yong Cui, Junmei Wang, and Song Lin
20354-20361
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A comparison of treatment modalities for nasal extranodal natural killer/Tcell lymphoma in early stages: The efficacy of CHOP regimen based concurrent chemoradiotherapy

https://doi.org/10.18632/oncotarget.13614

Jianzhong Cao, Shengmin Lan, Liuhai Shen, Hongwei Si, Ning Zhang, Hongwei Li, and Ruyuan Guo
20362-20370
Abstract  |  PDF  |  Full Text  |  How to cite

Efficacy of intermittent pneumatic compression for venous thromboembolism prophylaxis in patients undergoing gynecologic surgery: A systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.13620

Jian-Ping Feng, Yu-Ting Xiong, Zi-Qi Fan, Li-Jie Yan, Jing-Yun Wang, and Ze-Juan Gu
20371-20379
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Reviews

Multiple biological functions of Twist1 in various cancers

https://doi.org/10.18632/oncotarget.14608

Zhixiang Zhao, Mohammad Aminur Rahman, Zhuo G. Chen, and Dong M. Shin
20380-20393
Abstract  |  PDF  |  Full Text  |  How to cite

Bone marrow microenvironment is a crucial player for myelomagenesis and disease progression

https://doi.org/10.18632/oncotarget.14610

Patrizia Mondello, Salvatore Cuzzocrea, Michele Navarra, and Michael Mian
20394-20409
Abstract  |  PDF  |  Full Text  |  How to cite

Concurrent neoadjuvant chemoradiotherapy could improve survival outcomes for patients with esophageal cancer: a metaanalysis based on random clinical trials

https://doi.org/10.18632/oncotarget.14669

Baoxing Liu, Yacong Bo, Kunlun Wang, Yang Liu, Xiance Tang, Yan Zhao, Erjiang Zhao, and Ling Yuan
20410-20417
Abstract  |  PDF  |  Full Text  |  How to cite

The best strategy for HCC patients at each BCLC stage: a network metaanalysis of observational studies

https://doi.org/10.18632/oncotarget.14668

Lei Chang, Yitao Wang, Jibo Zhang, and Tao Guo
20418-20427
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Skeletal muscle aging: influence of oxidative stress and physical exercise

https://doi.org/10.18632/oncotarget.14670

Mariana Janini Gomes, Paula Felippe Martinez, Luana Urbano Pagan, Ricardo Luiz Damatto, Marcelo Diacardia Diacardia Mariano Cezar, Aline Regina Ruiz Lima, Katashi Okoshi, and Marina Politi Okoshi
20428-20440
Abstract  |  PDF  |  Full Text  |  How to cite

Efficacy of sequential therapies with sorafenibsunitinib versus sunitinibsorafenib in metastatic renal cell carcinoma: A systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.14671

Tingyu Wen, Hai Xiao, Chao Luo, Li Huang, and Meimei Xiong
20441-20451
Abstract  |  PDF  |  Full Text  |  How to cite

Homeodomaininteracting protein kinase 2 HIPK2: a promising target for anticancer therapies

https://doi.org/10.18632/oncotarget.14723

Yuanyuan Feng, Lihong Zhou, Xiaoting Sun, and Qi Li
20452-20461
Abstract  |  PDF  |  Full Text  |  How to cite

Long noncoding RNAs in osteosarcoma

https://doi.org/10.18632/oncotarget.14726

Ruiling Chen, Gangyang Wang, Ying Zheng, Yingqi Hua, and Zhengdong Cai
20462-20475
Abstract  |  PDF  |  Full Text  |  How to cite

SPECT and PET radiopharmaceuticals for molecular imaging of apoptosis: from bench to clinic

https://doi.org/10.18632/oncotarget.14730

Xiaobo Wang, Han Feng, Shichao Zhao, Junling Xu, Xinyu Wu, Jing Cui, Ying Zhang, Yuhua Qin, Zhiguo Liu, Tang Gao, Yongju Gao, and Wenbin Zeng
20476-20495
Abstract  |  PDF  |  Full Text  |  How to cite

Treatment of oral hyperpigmentation and gummy smile using lasers and role of plasma as a novel treatment technique in dentistry: An introductory review

https://doi.org/10.18632/oncotarget.14887

Nayansi Jha, Jae Jun Ryu, Rizwan Wahab, Abdulaziz A. Al-Khedhairy, Eun Ha Choi, and Nagendra Kumar Kaushik
20496-20509
Abstract  |  PDF  |  Full Text  |  How to cite

Case Reports

Significant efficacy and well safety of apatinib in an advanced liver cancer patient: a case report and literature review

https://doi.org/10.18632/oncotarget.14724

Peisi Kou, Yan Zhang, Wenbo Shao, Hui Zhu, Jingze Zhang, Haiyong Wang, Li Kong, and Jinming Yu
20510-20515
Abstract  |  PDF  |  Full Text  |  How to cite

Corrections

Correction: Estrogendependent downregulation of hypoxiainducible factor HIF2α in invasive breast cancer cells

https://doi.org/10.18632/oncotarget.16388

Jerry H. Fuady, Katrin Gutsche, Sara Santambrogio, Zsuzsanna Varga, David Hoogewijs, and Roland H. Wenger
20516-20516
Correction  |  PDF  |  How to cite


Copyright © 2026 Rapamycin Press LLC dba Impact Journals
Oncotarget ® is a registered trademark of Rapamycin Press LLC
Impact Journals ® is a registered trademark of Rapamycin Press LLC
RAPAMYCIN PRESS ® is a registered trademark of Rapamycin Press LLC
By using our site you are giving us permission to use cookies. This website collects cookies to deliver a better user experience, and to analyze our website traffic and performance. Personal data is not collected.