Long non-coding RNAs in osteosarcoma

Ruiling Chen; Gangyang Wang; Ying Zheng; Yingqi Hua; Zhengdong Cai

doi:10.18632/oncotarget.14726

Oncotarget

Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science.

Its scope is unique. The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. The term was introduced in the inaugural Editorial, Introducing Oncotarget.

As of January 1, 2022, Oncotarget has shifted to a continuous publishing model. Papers will now be published continuously within yearly volumes in their final and complete form and then quickly released to Pubmed.

Subscribe to receive alerts once a paper has been published by Oncotarget.

Learn about our FREE

Post-Publication Promotion Services

50% on all publication fees until the end of 2024.

Impact Journals, LLC is the publisher of Oncotarget: www.impactjournals.com.

Impact Journals is a member of the Wellcome Trust List of Compliant Publishers.

Impact Journals is a member of the Society for Scholarly Publishing.

On December 23, 2022, Oncotarget server experienced a DDoS attack. As a result, Oncotarget site was inaccessible for a few hours. Oncotarget team swiftly dealt with the situation and took it under control. This malicious action will be reported to the FBI.

Reviews:

Long non-coding RNAs in osteosarcoma

Ruiling Chen, Gangyang Wang, Ying Zheng, Yingqi Hua and Zhengdong Cai _

PDF | HTML | How to cite

Oncotarget. 2017; 8:20462-20475. https://doi.org/10.18632/oncotarget.14726

Metrics: PDF 2665 views | HTML 2672 views | ?

Abstract

Ruiling Chen1,*, Gangyang Wang1,*, Ying Zheng1, Yingqi Hua1 and Zhengdong Cai1

1 Department of Orthopaedics, Shanghai Bone Tumor Institute, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

* These authors have contributed equally to this work

Correspondence to:

Zhengdong Cai, email:

Yingqi Hua, email:

Keywords: osteosarcoma; lncRNA; pathogenesis; biomarkers; therapeutic targets

Received: October 12, 2016 Accepted: January 09, 2017 Published: January 18, 2017

Abstract

Long non-coding RNAs (lncRNAs) with more than 200 nuleotides, have been explored to participate in various cancer types including osteosarcoma (OS), which is the most common kind of primary bone tumors with high morbidity in infants and adolescents. These oncogenic or tumor suppressive lncRNAs regulate OS pathogenesis, such as cell growth, proliferation, invasion, migration, metastasis and cell apoptosis, serve as independent prognostic biomarkers or play a significant role in multidrug resistance (MDR) in OS cells. In this review, we attempt to dissect the participation of lncRNAs in pathogenesis of OS and their potential clinical values, and also provide an outlook for viable biomarkers and therapeutic targets in OS.

All site content, except where otherwise noted, is licensed under a Creative Commons Attribution 4.0 License.
PII: 14726

Publication Alerts

Post-Publication Promotion

Publication Discount

Reviews:

Long non-coding RNAs in osteosarcoma

Abstract