Vol 8, No 40

Distinct distributions of genomic features of the 5’ and 3’ partners of coding somatic cancer gene fusions: arising mechanisms and functional implications

Evaluation of the 7^th and 8^th editions of the AJCC/UICC TNM staging systems for lung cancer in a large North American cohort

Expression of hypothalamic neurohormones and their receptors in the human eye

NKL homeobox gene MSX1 acts like a tumor suppressor in NK-cell leukemia

Platelet-derived growth factor-C promotes human melanoma aggressiveness through activation of neuropilin-1

PD-L1 expression in bladder cancer and metastasis and its influence on oncologic outcome after cystectomy

Tenascin-C and fibronectin in normal esophageal mucosa, Barrett’s esophagus, dysplasia and adenocarcinoma

Establishment of a neuroendocrine prostate cancer model driven by the RNA splicing factor SRRM4

Multifunctional targeted liposomal drug delivery for efficient glioblastoma treatment

Detection of ESR1 mutations in circulating cell-free DNA from patients with metastatic breast cancer treated with palbociclib and letrozole

Bazedoxifene enhances the anti-tumor effects of cisplatin and radiation treatment by blocking IL-6 signaling in head and neck cancer

Mitochondrial mRNA transcripts predict overall survival, tumor recurrence and progression in serous ovarian cancer: Companion diagnostics for cancer therapy

Differences in risk factors of malignancy between men and women with type 2 diabetes: A retrospective case-control study

Upregulation of CFTR in patients with endometriosis and its involvement in NFκB-uPAR dependent cell migration

Tumor antigen glycosaminoglycan modification regulates antibody-drug conjugate delivery and cytotoxicity

The network of DAB2IP-miR-138 in regulating drug resistance of renal cell carcinoma associated with stem-like phenotypes

Aldose reductase interacts with AKT1 to augment hepatic AKT/ mTOR signaling and promote hepatocarcinogenesis

Dicer protein levels elevated by mild hyperthermia promote a pro-survival phenotype

Microtubule inhibitor, SP-6-27 inhibits angiogenesis and induces apoptosis in ovarian cancer cells

Meta-analysis of association between rs1447295 polymorphism and prostate cancer susceptibility

Aldehyde dehydrogenase 1A1 increases NADH levels and promotes tumor growth via glutathione/dihydrolipoic acid-dependent NAD⁺ reduction

Epigenomic study identifies a novel mesenchyme homeobox2-GLI1 transcription axis involved in cancer drug resistance, overall survival and therapy prognosis in lung cancer patients

Heat-killed salmonella typhimurium (HKST) protects mice against radiation in TLR4-dependent manner

Differentiated tumor immune microenvironment of Epstein–Barr virus-associated and negative gastric cancer: implication in prognosis and immunotherapy

1q/19p co-polysomy predicts longer survival in patients with astrocytic gliomas

Mitochondrial biomarkers predict tumor progression and poor overall survival in gastric cancers: Companion diagnostics for personalized medicine

Remarkably similar CTLA-4 binding properties of therapeutic ipilimumab and tremelimumab antibodies

Prognostic significance of HER3 in patients with malignant solid tumors

Genomic alterations in mucins across cancers

MiR-199a/b-5p inhibits hepatocellular carcinoma progression by post-transcriptionally suppressing ROCK1

Serum cystatin C is associated with large cerebral artery stenosis in acute ischemic stroke

Enhanced antiproliferative activity of antibody-functionalized polymeric nanoparticles for targeted delivery of anti-miR-21 to HER2 positive gastric cancer

Functional dissection of breast cancer risk-associated TERT promoter variants

A novel AMPK activator hernandezine inhibits LPS-induced TNFα production

Intrinsic remote conditioning of the myocardium as a comprehensive cardiac response to ischemia and reperfusion

Genetic profile and biological implication of PIN2/TRF1-interacting telomerase inhibitor 1 (PinX1) in human cancers: an analysis using The Cancer Genome Atlas

Hyperthermia and associated changes in membrane fluidity potentiate P2X7 activation to promote tumor cell death

Vitamin C and Doxycycline: A synthetic lethal combination therapy targeting metabolic flexibility in cancer stem cells (CSCs)

MYSM1/2A-DUB is an epigenetic regulator in human melanoma and contributes to tumor cell growth

Celastrol ameliorates inflammation through inhibition of NLRP3 inflammasome activation

Human CAFs promote lymphangiogenesis in ovarian cancer via the Hh-VEGF-C signaling axis

LncRNA ANCR down-regulation promotes TGF-β-induced EMT and metastasis in breast cancer

Peptide microarray profiling identifies phospholipase C gamma 1 (PLC-γ1) as a potential target for t(8;21) AML

Isolation and detection of circulating tumour cells from metastatic melanoma patients using a slanted spiral microfluidic device

Antitumor immunity induced by VE-cadherin modified DC vaccine

The cytosolic 5’-nucleotidase cN-II lowers the adaptability to glucose deprivation in human breast cancer cells

Sperm-carried RNAs play critical roles in mouse embryonic development

Translocation of heme oxygenase-1 contributes to imatinib resistance in chronic myelogenous leukemia

GTSE1: a novel TEAD4-E2F1 target gene involved in cell protrusions formation in triple-negative breast cancer cell models

Survival of metastatic melanoma patients after dendritic cell vaccination correlates with expression of leukocyte phosphatidylethanolamine-binding protein 1/Raf kinase inhibitory protein

Mitoriboscins: Mitochondrial-based therapeutics targeting cancer stem cells (CSCs), bacteria and pathogenic yeast

Positive correlation of cg16672562 methylation with obesity-related traits in childhood obesity, and its independence with underlying HIF3A (hypoxia-inducible factor 3a) genetic background

Restoring microenvironmental redox and pH homeostasis inhibits neoplastic cell growth and migration: therapeutic efficacy of esomeprazole plus sulfasalazine on 3-MCA-induced sarcoma

Micro RNA-155 plays a critical role in the initiation of food allergen-related inflammation in the intestine

ROS-independent Nrf2 activation in prostate cancer

Association of TERT polymorphisms and risk of coronary heart disease in a Chinese Han population

Mutational status of TP53 defines the efficacy of Wee1 inhibitor AZD1775 in KRAS-mutant non-small cell lung cancer

Identification of a novel metastasis inducing lncRNA which suppresses the KAI1/CD82 metastasis suppressor gene and is upregulated in triple-negative breast cancer

Heparin antagonizes cisplatin resistance of A2780 ovarian cancer cells by affecting the Wnt signaling pathway

Effects of soluble CPE on glioma cell migration are associated with mTOR activation and enhanced glucose flux

Therapeutic efficacy of SYM004, a mixture of two anti-EGFR antibodies in human colorectal cancer with acquired resistance to cetuximab and MET activation

Vitamin D deficiency causes insulin resistance by provoking oxidative stress in hepatocytes

HYAL2 methylation in peripheral blood as a potential marker for the detection of pancreatic cancer: a case control study

miR-30e* is overexpressed in prostate cancer and promotes NF-κB-mediated proliferation and tumor growth

Acute myeloid leukemia cells require 6-phosphogluconate dehydrogenase for cell growth and NADPH-dependent metabolic reprogramming

High pretreatment serum gamma-glutamyl transpeptidase predicts an inferior outcome in nasopharyngeal carcinoma

MiR-200c inhibits bladder cancer progression by targeting lactate dehydrogenase A

Dexamethasone affects cell growth/apoptosis/chemosensitivity of colon cancer via glucocorticoid receptor α/NF-κB

Predictive value of molecular subtyping in NMIBC by RT-qPCR of ERBB2, ESR1, PGR and MKI67 from formalin fixed TUR biopsies

Are three weeks hypofractionated radiation therapy (HFRT) comparable to six weeks for newly diagnosed glioblastoma patients? Results of a phase II study

The pan-BCL-2-blocker obatoclax (GX15-070) and the PI3-kinase/mTOR-inhibitor BEZ235 produce cooperative growth-inhibitory effects in ALL cells

ACYP2 polymorphisms are associated with the risk of liver cancer in a Han Chinese population

A nomogram predicting pathological complete response to neoadjuvant chemoradiotherapy for locally advanced rectal cancer: implications for organ preservation strategies

Analysis of long non-coding RNA expression profiles identifies novel lncRNA biomarkers in the tumorigenesis and malignant progression of gliomas

Cell cycle perturbation induced by gemcitabine in human tumor cells in cell culture, xenografts and bladder cancer patients: implications for clinical trial designs combining gemcitabine with a Chk1 inhibitor

ABI3, a component of the WAVE2 complex, is potentially regulated by PI3K/AKT pathway

Analyses of selected safety endpoints in phase 1 and late-phase clinical trials of anti-PD-1 and PD-L1 inhibitors: prediction of immune-related toxicities

Immunotherapy of WAP-T_NP mice with early stage mammary gland tumors

Presence of embryonic DNA in culture medium

Evaluation of digital PCR for detecting low-level EGFR mutations in advanced lung adenocarcinoma patients: a cross-platform comparison study

The abnormality of thyroid hormones in patients with type A hepatic encephalopathy

Cancer antigen 15-3, platelet distribution width, and fibrinogen in combination to distinguish breast cancer from benign breast disease in non-conclusive mammography patients

AM1241 alleviates MPTP-induced Parkinson's disease and promotes the regeneration of DA neurons in PD mice

The survival benefits of local surgery in stage IV breast cancer are not affected by breast cancer subtypes: a population-based analysis

A six-long non-coding RNAs signature as a potential prognostic marker for survival prediction of ER-positive breast cancer patients

Se₂Mo₁₀V₃, a heteropoly compound containing selenium, inhibits tumor growth

Expression patterns for nicotinic acetylcholine receptor subunit genes in smoking-related lung cancers

Integrated analysis of the molecular action of Vorinostat identifies epi-sensitised targets for combination therapy

EGFR signaling promotes inflammation and cancer stem-like activity in inflammatory breast cancer

Serum CA19-9 as a marker of circulating tumor cells in first reflux blood of colorectal cancer patients

Suppression of microRNA-384 enhances autophagy of airway smooth muscle cells in asthmatic mouse

AMPK activation-dependent autophagy compromises oleanolic acid-induced cytotoxicity in human bladder cancer cells

FIR haplodeficiency promotes splicing to pyruvate kinase M2 in mice thymic lymphoma tissues revealed by six-plex tandem mass tag quantitative proteomic analysis

SET contributes to the epithelial-mesenchymal transition of pancreatic cancer

Observation of elevated fasting blood glucose and functional outcome after ischemic stroke in patients with and without diabetes

Effects of roniciclib in preclinical models of anaplastic thyroid cancer

Low-dose photon irradiation induces invasiveness through the SDF-1α/CXCR4 pathway in malignant mesothelioma cells

Native glycan fragments detected by MALDI-FT-ICR mass spectrometry imaging impact gastric cancer biology and patient outcome

Molecular characterization of circulating colorectal tumor cells defines genetic signatures for individualized cancer care

DNA repair deregulation in discrete prostate cancer lesions identified on multi-parametric MRI and targeted by MRI/ultrasound fusion-guided biopsy

Melphalan modifies the bone microenvironment by enhancing osteoclast formation

CCAT-1 promotes proliferation and inhibits apoptosis of cervical cancer cells via the Wnt signaling pathway

Human HER2 overexpressing mouse breast cancer cell lines derived from MMTV.f.HuHER2 mice: characterization and use in a model of metastatic breast cancer

Cross-talk between p21-activated kinase 4 and ERα signaling triggers endometrial cancer cell proliferation

Mitochondrial markers predict survival and progression in non-small cell lung cancer (NSCLC) patients: Use as companion diagnostics

Markers of inflammation and influence of nitric oxide on platelet activation in the course of ulcerative colitis

Decreased mean platelet volume predicts poor prognosis in invasive bladder cancer

Acquisition of the T790M resistance mutation during afatinib treatment in EGFR tyrosine kinase inhibitor–naïve patients with non–small cell lung cancer harboring EGFR mutations

Age-specific sex difference in the incidence of hepatocellular carcinoma in the United States

The influence of adjuvant on UreB protection against Helicobacter pylori through the diversity of CD4+ T-cell epitope repertoire

Oridonin attenuates the release of pro-inflammatory cytokines in lipopolysaccharide-induced RAW264.7 cells and acute lung injury

A prospective appraisal of preoperative body mass index in D2-resected patients with non-metastatic gastric carcinoma and Siewert type II/III adenocarcinoma of esophagogastric junction: results from a large-scale cohort

FOXM1 facilitates gastric cancer cell migration and invasion by inducing Cathepsin D

Tunicamycin induced endoplasmic reticulum stress promotes apoptosis of prostate cancer cells by activating mTORC1

Sorafenib inhibits therapeutic induction of necroptosis in acute leukemia cells

Increased PD-L1 expression in erlotinib-resistant NSCLC cells with MET gene amplification is reversed upon MET-TKI treatment

TBX2 subfamily suppression in lung cancer pathogenesis: a high-potential marker for early detection

Homing in on an intracellular target for delivery of loaded nanoparticles functionalized with a histone deacetylase inhibitor

Pyruvate kinase M2 deregulation enhances the metastatic potential of tongue squamous cell carcinoma

MicroRNA-18a promotes proliferation and metastasis in hepatocellular carcinoma via targeting KLF4

Acquired tumor cell resistance to sunitinib by increased invasion and epithelial-mesenchymal transition in LL/2 murine lung cancer

Modulation of Dkk-3 and claudin-5 as new therapeutic strategy in the treatment of meningiomas

A regulatory role for the co-chaperone FKBP51s in PD-L1 expression in glioma

Regorafenib in combination with silybin as a novel potential strategy for the treatment of metastatic colorectal cancer

Systematic literature review and clinical validation of circulating microRNAs as diagnostic biomarkers for colorectal cancer

Decoding the full picture of Raf1 function based on its interacting proteins

Antiproliferative and pro-apoptotic activity of melatonin analogues on melanoma and breast cancer cells

Correlation between protein kinase catalytic subunit alpha-1 gene rs13361707 polymorphism and gastric cancer susceptibility in asian populations

iASPP overexpression is associated with clinical outcome in spinal chordoma and influences cellular proliferation, invasion, and sensitivity to cisplatin in vitro

SLC2A2 (GLUT2) as a novel prognostic factor for hepatocellular carcinoma

The degradation of mixed lineage kinase domain-like protein promotes neuroprotection after ischemic brain injury

Socioeconomic deprivation worsens the outcomes of Italian women with hormone receptor-positive breast cancer and decreases the possibility of receiving standard care

HIV-1 Gp120 clade B/C induces a GRP78 driven cytoprotective mechanism in astrocytoma

pSY153-MDR, a p12969-DIM-related mega plasmid carrying bla_IMP-45 and armA, from clinical Pseudomonas putida

Melanoma antigen A12 regulates cell cycle via tumor suppressor p21 expression

Body fat composition as predictive factor for treatment response in patients with newly diagnosed multiple myeloma – subgroup analysis of the prospective GMMG MM5 trial

Intravoxel incoherent motion MR imaging in nasopharyngeal carcinoma: comparison and correlation with dynamic contrast enhanced MR imaging

Expression profiles analysis reveals an integrated miRNA-lncRNA signature to predict survival in ovarian cancer patients with wild-type BRCA1/2

In-depth phenotyping of lymphoblastoid cells suggests selective cellular vulnerability in Marinesco-Sjögren syndrome

SAMHD1 acetylation enhances its deoxynucleotide triphosphohydrolase activity and promotes cancer cell proliferation

Preoperative imaging markers and PDZ-binding kinase tissue expression predict low-risk disease in endometrial hyperplasias and low grade cancers

Nanofat-derived stem cells with platelet-rich fibrin improve facial contour remodeling and skin rejuvenation after autologous structural fat transplantation

The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells

IL-33 blockade suppresses tumor growth of human lung cancer through direct and indirect pathways in a preclinical model

Frontline treatment with chemoimmunotherapy for limited-stage ocular adnexal MALT lymphoma with adverse factors: a phase II study

The pharmacological role of histone demethylase JMJD3 inhibitor GSK-J4 on glioma cells

Ex vivo multiplex profiling of protein tyrosine kinase activities in early stages of human lung adenocarcinoma

Glioblastoma progression is assisted by induction of immunosuppressive function of pericytes through interaction with tumor cells

Downregulation of miR-99a/let-7c/miR-125b miRNA cluster predicts clinical outcome in patients with unresected malignant pleural mesothelioma

Targeting the PI3K/AKT/mTOR signaling pathway as an effectively radiosensitizing strategy for treating human oral squamous cell carcinoma in vitro and in vivo

KRICT-9 inhibits neuroinflammation, amyloidogenesis and memory loss in Alzheimer’s disease models

Eriodictyol attenuates arsenic trioxide-induced liver injury by activation of Nrf2

Prognostic significance of GSTP1 in patients with triple negative breast cancer

Allergen specific immunotherapy enhanced defense against bacteria via TGF-β1-induced CYP27B1 in asthma

The long non-coding RNA NONHSAT062994 inhibits colorectal cancer by inactivating Akt signaling

PARP inhibitors protect against sex- and AAG-dependent alkylation-induced neural degeneration

Hsa-miR-429 promotes bladder cancer cell proliferation via inhibiting CDKN2B

Mitochondrial markers predict recurrence, metastasis and tamoxifen-resistance in breast cancer patients: Early detection of treatment failure with companion diagnostics

Concurrent somatic mutations in driver genes were significantly correlated with lymph node metastasis and pathological types in solid tumors

Novel SOX17 frameshift mutations in endometrial cancer are functionally distinct from recurrent missense mutations

A cerebrospinal fluid microRNA signature as biomarker for glioblastoma

Myoblast transplantation improves cardiac function after myocardial infarction through attenuating inflammatory responses

Meta-analysis of the association between three microRNA polymorphisms and breast cancer susceptibility

B7-H4 as an independent prognostic indicator of cancer patients: a meta-analysis

The elevated NLR, PLR and PLT may predict the prognosis of patients with colorectal cancer: a systematic review and meta-analysis

Thymosin-β4 inhibits proliferation and induces apoptosis of hepatic stellate cells through PI3K/AKT pathway

Effects of VEGF and VEGFR polymorphisms on the outcome of patients with metastatic renal cell carcinoma treated with sunitinib: a systematic review and meta-analysis

Diagnostic accuracy of BRCA1–associated protein 1 in malignant mesothelioma: a meta-analysis

Comparative efficacy and safety of Chinese herbal injections combined with the FOLFOX regimen for treating gastric cancer in China: a network meta-analysis

Comparative efficacy and safety of bone-modifying agents for the treatment of bone metastases in patients with advanced renal cell carcinoma: a systematic review and meta-analysis

Metabolomic biomarkers of pancreatic cancer: a meta-analysis study

Association between essential hypertension and bone mineral density: a systematic review and meta-analysis

The correlation between renal transplantation and liver carcinoma: a meta-analysis

Prognostic significance of neutrophil to lymphocyte ratio in ovarian cancer: evidence from 4,910 patients

Prognostic scores based on the preoperative plasma fibrinogen and serum albumin level as a prognostic factor in patients with upper urinary tract urothelial carcinoma

Thermal tomography for monitoring tumor response to neoadjuvant chemotherapy in women with locally advanced breast cancer

The diagnostic value of white blood cell, neutrophil, neutrophil-to-lymphocyte ratio, and lymphocyte-to-monocyte ratio in patients with primary angle closure glaucoma

Comparison of outcomes between trimodal therapy and radical cystectomy in muscle-invasive bladder cancer: a propensity score matching analysis

Combination of susceptibility gene and traditional risk factors might enhance the performance of coronary heart disease screening strategy

Dexmedetomidine attenuates acute paroxysmal sympathetic hyperactivity

Binostril endoscopic transsphenoidal neurosurgery for pituitary adenomas: experience with 42 patients

Anthropometric, clinical and molecular determinants of treatment outcomes in postmenopausal, hormone receptor positive metastatic breast cancer patients treated with fulvestrant: Results from a real word setting

Comparison of chemoradiotherapy with radiotherapy alone for “biopsy only” anaplastic astrocytoma

A review of the postoperative lymphatic leakage

PRAS40 signaling in tumor

Noncoding RNA in drug resistant sarcoma

Poly-(ADP-ribose)-polymerase inhibitors as radiosensitizers: a systematic review of pre-clinical and clinical human studies

Prognostic role of miR-17-92 family in human cancers: evaluation of multiple prognostic outcomes

The roles of signal transducer and activator of transcription factor 3 in tumor angiogenesis

Non-blood circulating tumor DNA detection in cancer

Long non-coding RNAs associated with non-small cell lung cancer

Culture conditions defining glioblastoma cells behavior: what is the impact for novel discoveries?