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About The Cover

The cover for issue 40 of Oncotarget features Figure 4, "Assessment of CRC patient tumoroid responses to cytotoxic drugs in vitro at 2 weeks following tumor resection," from Finnberg, et al.

Table of Contents

Priority Research Papers

Application of 3D tumoroid systems to define immune and cytotoxic therapeutic responses based on tumoroid and tissue slice culture molecular signatures

https://doi.org/10.18632/oncotarget.19965
66747-66757
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers

Adaptive metabolic rewiring to chronic SFK inhibition

https://doi.org/10.18632/oncotarget.8146
66758-66768
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Distinct distributions of genomic features of the 5’ and 3’ partners of coding somatic cancer gene fusions: arising mechanisms and functional implications

https://doi.org/10.18632/oncotarget.10734
66769-66783
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Evaluation of the 7th and 8th editions of the AJCC/UICC TNM staging systems for lung cancer in a large North American cohort

https://doi.org/10.18632/oncotarget.18158
66784-66795
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Expression of hypothalamic neurohormones and their receptors in the human eye

https://doi.org/10.18632/oncotarget.18358
66796-66814
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

NKL homeobox gene MSX1 acts like a tumor suppressor in NKcell leukemia

https://doi.org/10.18632/oncotarget.18609
66815-66832
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Plateletderived growth factorC promotes human melanoma aggressiveness through activation of neuropilin1

https://doi.org/10.18632/oncotarget.18706
66833-66848
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PDL1 expression in bladder cancer and metastasis and its influence on oncologic outcome after cystectomy

https://doi.org/10.18632/oncotarget.19913
66849-66864
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

TenascinC and fibronectin in normal esophageal mucosa Barrett’s esophagus dysplasia and adenocarcinoma

https://doi.org/10.18632/oncotarget.19196
66865-66877
Abstract  |  PDF  |  Full Text  |  How to cite

Establishment of a neuroendocrine prostate cancer model driven by the RNA splicing factor SRRM4

https://doi.org/10.18632/oncotarget.19916
66878-66888
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Multifunctional targeted liposomal drug delivery for efficient glioblastoma treatment

https://doi.org/10.18632/oncotarget.17976
66889-66900
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Detection of ESR1 mutations in circulating cellfree DNA from patients with metastatic breast cancer treated with palbociclib and letrozole

https://doi.org/10.18632/oncotarget.11383
66901-66911
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Bazedoxifene enhances the antitumor effects of cisplatin and radiation treatment by blocking IL6 signaling in head and neck cancer

https://doi.org/10.18632/oncotarget.11464
66912-66924
Abstract  |  PDF  |  Full Text  |  How to cite

Mitochondrial mRNA transcripts predict overall survival tumor recurrence and progression in serous ovarian cancer: Companion diagnostics for cancer therapy

https://doi.org/10.18632/oncotarget.19963
66925-66939
Abstract  |  PDF  |  Full Text  |  How to cite

Differences in risk factors of malignancy between men and women with type 2 diabetes: A retrospective casecontrol study

https://doi.org/10.18632/oncotarget.17716
66940-66950
Abstract  |  PDF  |  Full Text  |  How to cite

Upregulation of CFTR in patients with endometriosis and its involvement in NFκBuPAR dependent cell migration

https://doi.org/10.18632/oncotarget.16441
66951-66959
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tumor antigen glycosaminoglycan modification regulates antibodydrug conjugate delivery and cytotoxicity

https://doi.org/10.18632/oncotarget.16921
66960-66974
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The network of DAB2IPmiR138 in regulating drug resistance of renal cell carcinoma associated with stemlike phenotypes

https://doi.org/10.18632/oncotarget.17756
66975-66986
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Aldose reductase interacts with AKT1 to augment hepatic AKT/ mTOR signaling and promote hepatocarcinogenesis

https://doi.org/10.18632/oncotarget.17791
66987-67000
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Dicer protein levels elevated by mild hyperthermia promote a prosurvival phenotype

https://doi.org/10.18632/oncotarget.17433
67001-67016
Abstract  |  PDF  |  Full Text  |  How to cite

Microtubule inhibitor SP627 inhibits angiogenesis and induces apoptosis in ovarian cancer cells

https://doi.org/10.18632/oncotarget.17549
67017-67028
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Metaanalysis of association between rs1447295 polymorphism and prostate cancer susceptibility

https://doi.org/10.18632/oncotarget.17627
67029-67042
Abstract  |  PDF  |  Full Text  |  How to cite

Aldehyde dehydrogenase 1A1 increases NADH levels and promotes tumor growth via glutathione/dihydrolipoic aciddependent NAD+ reduction

https://doi.org/10.18632/oncotarget.17688
67043-67055
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Epigenomic study identifies a novel mesenchyme homeobox2GLI1 transcription axis involved in cancer drug resistance overall survival and therapy prognosis in lung cancer patients

https://doi.org/10.18632/oncotarget.17715
67056-67081
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Heatkilled salmonella typhimurium HKST protects mice against radiation in TLR4dependent manner

https://doi.org/10.18632/oncotarget.17859
67082-67093
Abstract  |  PDF  |  Full Text  |  How to cite

Differentiated tumor immune microenvironment of Epstein–Barr virusassociated and negative gastric cancer: implication in prognosis and immunotherapy

https://doi.org/10.18632/oncotarget.17945
67094-67103
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

1q/19p copolysomy predicts longer survival in patients with astrocytic gliomas

https://doi.org/10.18632/oncotarget.17947
67104-67116
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Mitochondrial biomarkers predict tumor progression and poor overall survival in gastric cancers: Companion diagnostics for personalized medicine

https://doi.org/10.18632/oncotarget.19962
67117-67128
Abstract  |  PDF  |  Full Text  |  How to cite

Remarkably similar CTLA4 binding properties of therapeutic ipilimumab and tremelimumab antibodies

https://doi.org/10.18632/oncotarget.18004
67129-67139
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prognostic significance of HER3 in patients with malignant solid tumors

https://doi.org/10.18632/oncotarget.18007
67140-67151
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genomic alterations in mucins across cancers

https://doi.org/10.18632/oncotarget.17934
67152-67168
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR199a/b5p inhibits hepatocellular carcinoma progression by posttranscriptionally suppressing ROCK1

https://doi.org/10.18632/oncotarget.18052
67169-67180
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Serum cystatin C is associated with large cerebral artery stenosis in acute ischemic stroke

https://doi.org/10.18632/oncotarget.18061
67181-67188
Abstract  |  PDF  |  Full Text  |  How to cite

Enhanced antiproliferative activity of antibodyfunctionalized polymeric nanoparticles for targeted delivery of antimiR21 to HER2 positive gastric cancer

https://doi.org/10.18632/oncotarget.18066
67189-67202
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Functional dissection of breast cancer riskassociated TERT promoter variants

https://doi.org/10.18632/oncotarget.18226
67203-67217
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A novel AMPK activator hernandezine inhibits LPSinduced TNFα production

https://doi.org/10.18632/oncotarget.18365
67218-67226
Abstract  |  PDF  |  Full Text  |  How to cite

Intrinsic remote conditioning of the myocardium as a comprehensive cardiac response to ischemia and reperfusion

https://doi.org/10.18632/oncotarget.18438
67227-67240
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genetic profile and biological implication of PIN2/TRF1interacting telomerase inhibitor 1 PinX1 in human cancers: an analysis using The Cancer Genome Atlas

https://doi.org/10.18632/oncotarget.18589
67241-67253
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Hyperthermia and associated changes in membrane fluidity potentiate P2X7 activation to promote tumor cell death

https://doi.org/10.18632/oncotarget.18595
67254-67268
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Vitamin C and Doxycycline: A synthetic lethal combination therapy targeting metabolic flexibility in cancer stem cells CSCs

https://doi.org/10.18632/oncotarget.18428
67269-67286
Abstract  |  PDF  |  Full Text  |  How to cite

MYSM1/2ADUB is an epigenetic regulator in human melanoma and contributes to tumor cell growth

https://doi.org/10.18632/oncotarget.18617
67287-67299
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Celastrol ameliorates inflammation through inhibition of NLRP3 inflammasome activation

https://doi.org/10.18632/oncotarget.18619
67300-67314
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Human CAFs promote lymphangiogenesis in ovarian cancer via the HhVEGFC signaling axis

https://doi.org/10.18632/oncotarget.18621
67315-67328
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

LncRNA ANCR downregulation promotes TGFβinduced EMT and metastasis in breast cancer

https://doi.org/10.18632/oncotarget.18622
67329-67343
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Peptide microarray profiling identifies phospholipase C gamma 1 PLCγ1 as a potential target for t8;21 AML

https://doi.org/10.18632/oncotarget.18631
67344-67354
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Isolation and detection of circulating tumour cells from metastatic melanoma patients using a slanted spiral microfluidic device

https://doi.org/10.18632/oncotarget.18641
67355-67368
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Antitumor immunity induced by VEcadherin modified DC vaccine

https://doi.org/10.18632/oncotarget.18654
67369-67379
Abstract  |  PDF  |  Full Text  |  How to cite

The cytosolic 5’nucleotidase cNII lowers the adaptability to glucose deprivation in human breast cancer cells

https://doi.org/10.18632/oncotarget.18653
67380-67393
Abstract  |  PDF  |  Full Text  |  How to cite

Spermcarried RNAs play critical roles in mouse embryonic development

https://doi.org/10.18632/oncotarget.18672
67394-67405
Abstract  |  PDF  |  Full Text  |  How to cite

Translocation of heme oxygenase1 contributes to imatinib resistance in chronic myelogenous leukemia

https://doi.org/10.18632/oncotarget.18684
67406-67421
Abstract  |  PDF  |  Full Text  |  How to cite

GTSE1: a novel TEAD4E2F1 target gene involved in cell protrusions formation in triplenegative breast cancer cell models

https://doi.org/10.18632/oncotarget.18691
67422-67438
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Survival of metastatic melanoma patients after dendritic cell vaccination correlates with expression of leukocyte phosphatidylethanolaminebinding protein 1/Raf kinase inhibitory protein

https://doi.org/10.18632/oncotarget.18698
67439-67456
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Mitoriboscins: Mitochondrialbased therapeutics targeting cancer stem cells CSCs bacteria and pathogenic yeast

https://doi.org/10.18632/oncotarget.19084
67457-67472
Abstract  |  PDF  |  Full Text  |  How to cite

Positive correlation of cg16672562 methylation with obesityrelated traits in childhood obesity and its independence with underlying HIF3A hypoxiainducible factor 3a genetic background

https://doi.org/10.18632/oncotarget.18707
67473-67481
Abstract  |  PDF  |  Full Text  |  How to cite

Restoring microenvironmental redox and pH homeostasis inhibits neoplastic cell growth and migration: therapeutic efficacy of esomeprazole plus sulfasalazine on 3MCAinduced sarcoma

https://doi.org/10.18632/oncotarget.18713
67482-67496
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Micro RNA155 plays a critical role in the initiation of food allergenrelated inflammation in the intestine

https://doi.org/10.18632/oncotarget.18723
67497-67505
Abstract  |  PDF  |  Full Text  |  How to cite

ROSindependent Nrf2 activation in prostate cancer

https://doi.org/10.18632/oncotarget.18724
67506-67518
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Association of TERT polymorphisms and risk of coronary heart disease in a Chinese Han population

https://doi.org/10.18632/oncotarget.18727
67519-67525
Abstract  |  PDF  |  Full Text  |  How to cite

Mutational status of TP53 defines the efficacy of Wee1 inhibitor AZD1775 in KRASmutant nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.18728
67526-67537
Abstract  |  PDF  |  Full Text  |  How to cite

Identification of a novel metastasis inducing lncRNA which suppresses the KAI1/CD82 metastasis suppressor gene and is upregulated in triplenegative breast cancer

https://doi.org/10.18632/oncotarget.18733
67538-67552
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Heparin antagonizes cisplatin resistance of A2780 ovarian cancer cells by affecting the Wnt signaling pathway

https://doi.org/10.18632/oncotarget.18738
67553-67566
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Effects of soluble CPE on glioma cell migration are associated with mTOR activation and enhanced glucose flux

https://doi.org/10.18632/oncotarget.18747
67567-67591
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Therapeutic efficacy of SYM004 a mixture of two antiEGFR antibodies in human colorectal cancer with acquired resistance to cetuximab and MET activation

https://doi.org/10.18632/oncotarget.18749
67592-67604
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Vitamin D deficiency causes insulin resistance by provoking oxidative stress in hepatocytes

https://doi.org/10.18632/oncotarget.18754
67605-67613
Abstract  |  PDF  |  Full Text  |  How to cite

HYAL2 methylation in peripheral blood as a potential marker for the detection of pancreatic cancer: a case control study

https://doi.org/10.18632/oncotarget.18757
67614-67625
Abstract  |  PDF  |  Full Text  |  How to cite

miR30e* is overexpressed in prostate cancer and promotes NFκBmediated proliferation and tumor growth

https://doi.org/10.18632/oncotarget.18795
67626-67638
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Acute myeloid leukemia cells require 6phosphogluconate dehydrogenase for cell growth and NADPHdependent metabolic reprogramming

https://doi.org/10.18632/oncotarget.18797
67639-67650
Abstract  |  PDF  |  Full Text  |  How to cite

High pretreatment serum gammaglutamyl transpeptidase predicts an inferior outcome in nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.18798
67651-67662
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR200c inhibits bladder cancer progression by targeting lactate dehydrogenase A

https://doi.org/10.18632/oncotarget.18801
67663-67669
Abstract  |  PDF  |  Full Text  |  How to cite

Dexamethasone affects cell growth/apoptosis/chemosensitivity of colon cancer via glucocorticoid receptor α/NFκB

https://doi.org/10.18632/oncotarget.18802
67670-67683
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Predictive value of molecular subtyping in NMIBC by RTqPCR of ERBB2 ESR1 PGR and MKI67 from formalin fixed TUR biopsies

https://doi.org/10.18632/oncotarget.18804
67684-67695
Abstract  |  PDF  |  Full Text  |  How to cite

Are three weeks hypofractionated radiation therapy HFRT comparable to six weeks for newly diagnosed glioblastoma patients Results of a phase II study

https://doi.org/10.18632/oncotarget.18809
67696-67708
Abstract  |  PDF  |  Full Text  |  How to cite

The panBCL2blocker obatoclax GX15070 and the PI3kinase/mTORinhibitor BEZ235 produce cooperative growthinhibitory effects in ALL cells

https://doi.org/10.18632/oncotarget.18810
67709-67722
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ACYP2 polymorphisms are associated with the risk of liver cancer in a Han Chinese population

https://doi.org/10.18632/oncotarget.18574
67723-67731
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A nomogram predicting pathological complete response to neoadjuvant chemoradiotherapy for locally advanced rectal cancer: implications for organ preservation strategies

https://doi.org/10.18632/oncotarget.18821
67732-67743
Abstract  |  PDF  |  Full Text  |  How to cite

Analysis of long noncoding RNA expression profiles identifies novel lncRNA biomarkers in the tumorigenesis and malignant progression of gliomas

https://doi.org/10.18632/oncotarget.18832
67744-67753
Abstract  |  PDF  |  Full Text  |  How to cite

Cell cycle perturbation induced by gemcitabine in human tumor cells in cell culture xenografts and bladder cancer patients: implications for clinical trial designs combining gemcitabine with a Chk1 inhibitor

https://doi.org/10.18632/oncotarget.18834
67754-67768
Abstract  |  PDF  |  Full Text  |  How to cite

ABI3 a component of the WAVE2 complex is potentially regulated by PI3K/AKT pathway

https://doi.org/10.18632/oncotarget.18840
67769-67781
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Analyses of selected safety endpoints in phase 1 and latephase clinical trials of antiPD1 and PDL1 inhibitors: prediction of immunerelated toxicities

https://doi.org/10.18632/oncotarget.18847
67782-67789
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Immunotherapy of WAPTNP mice with early stage mammary gland tumors

https://doi.org/10.18632/oncotarget.18850
67790-67804
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Presence of embryonic DNA in culture medium

https://doi.org/10.18632/oncotarget.18852
67805-67809
Abstract  |  PDF  |  Full Text  |  How to cite

Evaluation of digital PCR for detecting lowlevel EGFR mutations in advanced lung adenocarcinoma patients: a crossplatform comparison study

https://doi.org/10.18632/oncotarget.18866
67810-67820
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The abnormality of thyroid hormones in patients with type A hepatic encephalopathy

https://doi.org/10.18632/oncotarget.18869
67821-67828
Abstract  |  PDF  |  Full Text  |  How to cite

Cancer antigen 153 platelet distribution width and fibrinogen in combination to distinguish breast cancer from benign breast disease in nonconclusive mammography patients

https://doi.org/10.18632/oncotarget.18870
67829-67836
Abstract  |  PDF  |  Full Text  |  How to cite

AM1241 alleviates MPTPinduced Parkinson's disease and promotes the regeneration of DA neurons in PD mice

https://doi.org/10.18632/oncotarget.18871
67837-67850
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The survival benefits of local surgery in stage IV breast cancer are not affected by breast cancer subtypes: a populationbased analysis

https://doi.org/10.18632/oncotarget.18889
67851-67860
Abstract  |  PDF  |  Full Text  |  How to cite

A sixlong noncoding RNAs signature as a potential prognostic marker for survival prediction of ERpositive breast cancer patients

https://doi.org/10.18632/oncotarget.18919
67861-67870
Abstract  |  PDF  |  Full Text  |  How to cite

Se2Mo10V3 a heteropoly compound containing selenium inhibits tumor growth

https://doi.org/10.18632/oncotarget.18909
67871-67877
Abstract  |  PDF  |  Full Text  |  How to cite

Expression patterns for nicotinic acetylcholine receptor subunit genes in smokingrelated lung cancers

https://doi.org/10.18632/oncotarget.18948
67878-67890
Abstract  |  PDF  |  Full Text  |  How to cite

Integrated analysis of the molecular action of Vorinostat identifies episensitised targets for combination therapy

https://doi.org/10.18632/oncotarget.18910
67891-67903
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

EGFR signaling promotes inflammation and cancer stemlike activity in inflammatory breast cancer

https://doi.org/10.18632/oncotarget.18958
67904-67917
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Serum CA199 as a marker of circulating tumor cells in first reflux blood of colorectal cancer patients

https://doi.org/10.18632/oncotarget.18912
67918-67932
Abstract  |  PDF  |  Full Text  |  How to cite

Suppression of microRNA384 enhances autophagy of airway smooth muscle cells in asthmatic mouse

https://doi.org/10.18632/oncotarget.18913
67933-67941
Abstract  |  PDF  |  Full Text  |  How to cite

AMPK activationdependent autophagy compromises oleanolic acidinduced cytotoxicity in human bladder cancer cells

https://doi.org/10.18632/oncotarget.18980
67942-67954
Abstract  |  PDF  |  Full Text  |  How to cite

FIR haplodeficiency promotes splicing to pyruvate kinase M2 in mice thymic lymphoma tissues revealed by sixplex tandem mass tag quantitative proteomic analysis

https://doi.org/10.18632/oncotarget.19061
67955-67965
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

SET contributes to the epithelialmesenchymal transition of pancreatic cancer

https://doi.org/10.18632/oncotarget.19067
67966-67979
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Observation of elevated fasting blood glucose and functional outcome after ischemic stroke in patients with and without diabetes

https://doi.org/10.18632/oncotarget.19074
67980-67989
Abstract  |  PDF  |  Full Text  |  How to cite

Effects of roniciclib in preclinical models of anaplastic thyroid cancer

https://doi.org/10.18632/oncotarget.19092
67990-68000
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Lowdose photon irradiation induces invasiveness through the SDF1α/CXCR4 pathway in malignant mesothelioma cells

https://doi.org/10.18632/oncotarget.19134
68001-68011
Abstract  |  PDF  |  Full Text  |  How to cite

Native glycan fragments detected by MALDIFTICR mass spectrometry imaging impact gastric cancer biology and patient outcome

https://doi.org/10.18632/oncotarget.19137
68012-68025
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Molecular characterization of circulating colorectal tumor cells defines genetic signatures for individualized cancer care

https://doi.org/10.18632/oncotarget.19138
68026-68037
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

DNA repair deregulation in discrete prostate cancer lesions identified on multiparametric MRI and targeted by MRI/ultrasound fusionguided biopsy

https://doi.org/10.18632/oncotarget.19145
68038-68046
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Melphalan modifies the bone microenvironment by enhancing osteoclast formation

https://doi.org/10.18632/oncotarget.19152
68047-68058
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

CCAT1 promotes proliferation and inhibits apoptosis of cervical cancer cells via the Wnt signaling pathway

https://doi.org/10.18632/oncotarget.19155
68059-68070
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Human HER2 overexpressing mouse breast cancer cell lines derived from MMTVfHuHER2 mice: characterization and use in a model of metastatic breast cancer

https://doi.org/10.18632/oncotarget.19174
68071-68082
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Crosstalk between p21activated kinase 4 and ERα signaling triggers endometrial cancer cell proliferation

https://doi.org/10.18632/oncotarget.19188
68083-68094
Abstract  |  PDF  |  Full Text  |  How to cite

Mitochondrial markers predict survival and progression in nonsmall cell lung cancer NSCLC patients: Use as companion diagnostics

https://doi.org/10.18632/oncotarget.19677
68095-68107
Abstract  |  PDF  |  Full Text  |  How to cite
Special Collection ToC

Markers of inflammation and influence of nitric oxide on platelet activation in the course of ulcerative colitis

https://doi.org/10.18632/oncotarget.19202
68108-68114
Abstract  |  PDF  |  Full Text  |  How to cite

Decreased mean platelet volume predicts poor prognosis in invasive bladder cancer

https://doi.org/10.18632/oncotarget.19242
68115-68122
Abstract  |  PDF  |  Full Text  |  How to cite

Acquisition of the T790M resistance mutation during afatinib treatment in EGFR tyrosine kinase inhibitor–naïve patients with non–small cell lung cancer harboring EGFR mutations

https://doi.org/10.18632/oncotarget.19243
68123-68130
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Agespecific sex difference in the incidence of hepatocellular carcinoma in the United States

https://doi.org/10.18632/oncotarget.19245
68131-68137
Abstract  |  PDF  |  Full Text  |  How to cite

The influence of adjuvant on UreB protection against Helicobacter pylori through the diversity of CD4+ Tcell epitope repertoire

https://doi.org/10.18632/oncotarget.19248
68138-68152
Abstract  |  PDF  |  Full Text  |  How to cite

Oridonin attenuates the release of proinflammatory cytokines in lipopolysaccharideinduced RAW2647 cells and acute lung injury

https://doi.org/10.18632/oncotarget.19249
68153-68164
Abstract  |  PDF  |  Full Text  |  How to cite

A prospective appraisal of preoperative body mass index in D2resected patients with nonmetastatic gastric carcinoma and Siewert type II/III adenocarcinoma of esophagogastric junction: results from a largescale cohort

https://doi.org/10.18632/oncotarget.19251
68165-68179
Abstract  |  PDF  |  Full Text  |  How to cite

FOXM1 facilitates gastric cancer cell migration and invasion by inducing Cathepsin D

https://doi.org/10.18632/oncotarget.19254
68180-68190
Abstract  |  PDF  |  Full Text  |  How to cite

Tunicamycin induced endoplasmic reticulum stress promotes apoptosis of prostate cancer cells by activating mTORC1

https://doi.org/10.18632/oncotarget.19277
68191-68207
Abstract  |  PDF  |  Full Text  |  How to cite

Sorafenib inhibits therapeutic induction of necroptosis in acute leukemia cells

https://doi.org/10.18632/oncotarget.19919
68208-68220
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Increased PDL1 expression in erlotinibresistant NSCLC cells with MET gene amplification is reversed upon METTKI treatment

https://doi.org/10.18632/oncotarget.19920
68221-68229
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

TBX2 subfamily suppression in lung cancer pathogenesis: a highpotential marker for early detection

https://doi.org/10.18632/oncotarget.19938
68230-68241
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Homing in on an intracellular target for delivery of loaded nanoparticles functionalized with a histone deacetylase inhibitor

https://doi.org/10.18632/oncotarget.20021
68242-68251
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Pyruvate kinase M2 deregulation enhances the metastatic potential of tongue squamous cell carcinoma

https://doi.org/10.18632/oncotarget.19291
68252-68262
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MicroRNA18a promotes proliferation and metastasis in hepatocellular carcinoma via targeting KLF4

https://doi.org/10.18632/oncotarget.19293
68263-68269
Abstract  |  PDF  |  Full Text  |  How to cite

Acquired tumor cell resistance to sunitinib by increased invasion and epithelialmesenchymal transition in LL/2 murine lung cancer

https://doi.org/10.18632/oncotarget.19295
68270-68279
Abstract  |  PDF  |  Full Text  |  How to cite

Modulation of Dkk3 and claudin5 as new therapeutic strategy in the treatment of meningiomas

https://doi.org/10.18632/oncotarget.20047
68280-68290
Abstract  |  PDF  |  Full Text  |  How to cite

A regulatory role for the cochaperone FKBP51s in PDL1 expression in glioma

https://doi.org/10.18632/oncotarget.19309
68291-68304
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Regorafenib in combination with silybin as a novel potential strategy for the treatment of metastatic colorectal cancer

https://doi.org/10.18632/oncotarget.20054
68305-68316
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Systematic literature review and clinical validation of circulating microRNAs as diagnostic biomarkers for colorectal cancer

https://doi.org/10.18632/oncotarget.19344
68317-68328
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Decoding the full picture of Raf1 function based on its interacting proteins

https://doi.org/10.18632/oncotarget.19353
68329-68337
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Antiproliferative and proapoptotic activity of melatonin analogues on melanoma and breast cancer cells

https://doi.org/10.18632/oncotarget.20124
68338-68353
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Correlation between protein kinase catalytic subunit alpha1 gene rs13361707 polymorphism and gastric cancer susceptibility in asian populations

https://doi.org/10.18632/oncotarget.19355
68354-68364
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

iASPP overexpression is associated with clinical outcome in spinal chordoma and influences cellular proliferation invasion and sensitivity to cisplatin in vitro

https://doi.org/10.18632/oncotarget.20190
68365-68380
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

SLC2A2 GLUT2 as a novel prognostic factor for hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.20266
68381-68392
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The degradation of mixed lineage kinase domainlike protein promotes neuroprotection after ischemic brain injury

https://doi.org/10.18632/oncotarget.19416
68393-68401
Abstract  |  PDF  |  Full Text  |  How to cite

Socioeconomic deprivation worsens the outcomes of Italian women with hormone receptorpositive breast cancer and decreases the possibility of receiving standard care

https://doi.org/10.18632/oncotarget.19447
68402-68414
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

HIV1 Gp120 clade B/C induces a GRP78 driven cytoprotective mechanism in astrocytoma

https://doi.org/10.18632/oncotarget.19474
68415-68438
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

pSY153MDR a p12969DIMrelated mega plasmid carrying blaIMP45 and armA from clinical Pseudomonas putida

https://doi.org/10.18632/oncotarget.19496
68439-68447
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Melanoma antigen A12 regulates cell cycle via tumor suppressor p21 expression

https://doi.org/10.18632/oncotarget.19497
68448-68459
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Body fat composition as predictive factor for treatment response in patients with newly diagnosed multiple myeloma – subgroup analysis of the prospective GMMG MM5 trial

https://doi.org/10.18632/oncotarget.19536
68460-68471
Abstract  |  PDF  |  Full Text  |  How to cite

Intravoxel incoherent motion MR imaging in nasopharyngeal carcinoma: comparison and correlation with dynamic contrast enhanced MR imaging

https://doi.org/10.18632/oncotarget.19575
68472-68482
Abstract  |  PDF  |  Full Text  |  How to cite

Expression profiles analysis reveals an integrated miRNAlncRNA signature to predict survival in ovarian cancer patients with wildtype BRCA1/2

https://doi.org/10.18632/oncotarget.19590
68483-68492
Abstract  |  PDF  |  Full Text  |  How to cite

Indepth phenotyping of lymphoblastoid cells suggests selective cellular vulnerability in MarinescoSjögren syndrome

https://doi.org/10.18632/oncotarget.19663
68493-68516
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

SAMHD1 acetylation enhances its deoxynucleotide triphosphohydrolase activity and promotes cancer cell proliferation

https://doi.org/10.18632/oncotarget.19704
68517-68529
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Preoperative imaging markers and PDZbinding kinase tissue expression predict lowrisk disease in endometrial hyperplasias and low grade cancers

https://doi.org/10.18632/oncotarget.19708
68530-68541
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Nanofatderived stem cells with plateletrich fibrin improve facial contour remodeling and skin rejuvenation after autologous structural fat transplantation

https://doi.org/10.18632/oncotarget.19721
68542-68556
Abstract  |  PDF  |  Full Text  |  How to cite

The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells

https://doi.org/10.18632/oncotarget.19782
68557-68570
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

IL33 blockade suppresses tumor growth of human lung cancer through direct and indirect pathways in a preclinical model

https://doi.org/10.18632/oncotarget.19786
68571-68582
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Frontline treatment with chemoimmunotherapy for limitedstage ocular adnexal MALT lymphoma with adverse factors: a phase II study

https://doi.org/10.18632/oncotarget.19788
68583-68590
Abstract  |  PDF  |  Full Text  |  How to cite

The pharmacological role of histone demethylase JMJD3 inhibitor GSKJ4 on glioma cells

https://doi.org/10.18632/oncotarget.19793
68591-68598
Abstract  |  PDF  |  Full Text  |  How to cite

Ex vivo multiplex profiling of protein tyrosine kinase activities in early stages of human lung adenocarcinoma

https://doi.org/10.18632/oncotarget.19803
68599-68613
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Glioblastoma progression is assisted by induction of immunosuppressive function of pericytes through interaction with tumor cells

https://doi.org/10.18632/oncotarget.19804
68614-68626
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Downregulation of miR99a/let7c/miR125b miRNA cluster predicts clinical outcome in patients with unresected malignant pleural mesothelioma

https://doi.org/10.18632/oncotarget.19800
68627-68640
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Targeting the PI3K/AKT/mTOR signaling pathway as an effectively radiosensitizing strategy for treating human oral squamous cell carcinoma in vitro and in vivo

https://doi.org/10.18632/oncotarget.19817
68641-68653
Abstract  |  PDF  |  Full Text  |  How to cite

KRICT9 inhibits neuroinflammation amyloidogenesis and memory loss in Alzheimer’s disease models

https://doi.org/10.18632/oncotarget.19818
68654-68667
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Eriodictyol attenuates arsenic trioxideinduced liver injury by activation of Nrf2

https://doi.org/10.18632/oncotarget.19822
68668-68674
Abstract  |  PDF  |  Full Text  |  How to cite

Prognostic significance of GSTP1 in patients with triple negative breast cancer

https://doi.org/10.18632/oncotarget.19824
68675-68680
Abstract  |  PDF  |  Full Text  |  How to cite

Allergen specific immunotherapy enhanced defense against bacteria via TGFβ1induced CYP27B1 in asthma

https://doi.org/10.18632/oncotarget.19826
68681-68695
Abstract  |  PDF  |  Full Text  |  How to cite

The long noncoding RNA NONHSAT062994 inhibits colorectal cancer by inactivating Akt signaling

https://doi.org/10.18632/oncotarget.19827
68696-68706
Abstract  |  PDF  |  Full Text  |  How to cite

PARP inhibitors protect against sex and AAGdependent alkylationinduced neural degeneration

https://doi.org/10.18632/oncotarget.19844
68707-68720
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

HsamiR429 promotes bladder cancer cell proliferation via inhibiting CDKN2B

https://doi.org/10.18632/oncotarget.19878
68721-68729
Abstract  |  PDF  |  Full Text  |  How to cite

Mitochondrial markers predict recurrence metastasis and tamoxifenresistance in breast cancer patients: Early detection of treatment failure with companion diagnostics

https://doi.org/10.18632/oncotarget.19612
68730-68745
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Concurrent somatic mutations in driver genes were significantly correlated with lymph node metastasis and pathological types in solid tumors

https://doi.org/10.18632/oncotarget.19975
68746-68757
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Novel SOX17 frameshift mutations in endometrial cancer are functionally distinct from recurrent missense mutations

https://doi.org/10.18632/oncotarget.20213
68758-68768
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A cerebrospinal fluid microRNA signature as biomarker for glioblastoma

https://doi.org/10.18632/oncotarget.18332
68769-68779
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Myoblast transplantation improves cardiac function after myocardial infarction through attenuating inflammatory responses

https://doi.org/10.18632/oncotarget.18244
68780-68794
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Meta-Analysis

The optimal time of initiation of renal replacement therapy in acute kidney injury: A metaanalysis

https://doi.org/10.18632/oncotarget.17946
68795-68808
Abstract  |  PDF  |  Full Text  |  How to cite

Metaanalysis of the association between three microRNA polymorphisms and breast cancer susceptibility

https://doi.org/10.18632/oncotarget.18516
68809-68824
Abstract  |  PDF  |  Full Text  |  How to cite

B7H4 as an independent prognostic indicator of cancer patients: a metaanalysis

https://doi.org/10.18632/oncotarget.18566
68825-68836
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The elevated NLR PLR and PLT may predict the prognosis of patients with colorectal cancer: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.18575
68837-68846
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Thymosinβ4 inhibits proliferation and induces apoptosis of hepatic stellate cells through PI3K/AKT pathway

https://doi.org/10.18632/oncotarget.18748
68847-68853
Abstract  |  PDF  |  Full Text  |  How to cite

Effects of VEGF and VEGFR polymorphisms on the outcome of patients with metastatic renal cell carcinoma treated with sunitinib: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.19924
68854-68862
Abstract  |  PDF  |  Full Text  |  How to cite

Diagnostic accuracy of BRCA1–associated protein 1 in malignant mesothelioma: a metaanalysis

https://doi.org/10.18632/oncotarget.20317
68863-68872
Abstract  |  PDF  |  Full Text  |  How to cite

Comparative efficacy and safety of Chinese herbal injections combined with the FOLFOX regimen for treating gastric cancer in China: a network metaanalysis

https://doi.org/10.18632/oncotarget.20320
68873-68889
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Comparative efficacy and safety of bonemodifying agents for the treatment of bone metastases in patients with advanced renal cell carcinoma: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.20323
68890-68898
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Metabolomic biomarkers of pancreatic cancer: a metaanalysis study

https://doi.org/10.18632/oncotarget.20324
68899-68915
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Association between essential hypertension and bone mineral density: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.20325
68916-68927
Abstract  |  PDF  |  Full Text  |  How to cite

The correlation between renal transplantation and liver carcinoma: a metaanalysis

https://doi.org/10.18632/oncotarget.19456
68928-68937
Abstract  |  PDF  |  Full Text  |  How to cite

Prognostic significance of neutrophil to lymphocyte ratio in ovarian cancer: evidence from 4910 patients

https://doi.org/10.18632/oncotarget.20196
68938-68949
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinical Research Papers

Imatinib in systemic mastocytosis: a phase IV clinical trial in patients lacking exon 17 KIT mutations and review of the literature

https://doi.org/10.18632/oncotarget.10711
68950-68963
Abstract  |  PDF  |  Full Text  |  How to cite

Prognostic scores based on the preoperative plasma fibrinogen and serum albumin level as a prognostic factor in patients with upper urinary tract urothelial carcinoma

https://doi.org/10.18632/oncotarget.16483
68964-68973
Abstract  |  PDF  |  Full Text  |  How to cite

Thermal tomography for monitoring tumor response to neoadjuvant chemotherapy in women with locally advanced breast cancer

https://doi.org/10.18632/oncotarget.16569
68974-68983
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The diagnostic value of white blood cell neutrophil neutrophiltolymphocyte ratio and lymphocytetomonocyte ratio in patients with primary angle closure glaucoma

https://doi.org/10.18632/oncotarget.16571
68984-68995
Abstract  |  PDF  |  Full Text  |  How to cite

Comparison of outcomes between trimodal therapy and radical cystectomy in muscleinvasive bladder cancer: a propensity score matching analysis

https://doi.org/10.18632/oncotarget.16576
68996-69004
Abstract  |  PDF  |  Full Text  |  How to cite

Combination of susceptibility gene and traditional risk factors might enhance the performance of coronary heart disease screening strategy

https://doi.org/10.18632/oncotarget.16692
69005-69011
Abstract  |  PDF  |  Full Text  |  How to cite

Dexmedetomidine attenuates acute paroxysmal sympathetic hyperactivity

https://doi.org/10.18632/oncotarget.16920
69012-69019
Abstract  |  PDF  |  Full Text  |  How to cite

Binostril endoscopic transsphenoidal neurosurgery for pituitary adenomas: experience with 42 patients

https://doi.org/10.18632/oncotarget.16976
69020-69024
Abstract  |  PDF  |  Full Text  |  How to cite

Anthropometric clinical and molecular determinants of treatment outcomes in postmenopausal hormone receptor positive metastatic breast cancer patients treated with fulvestrant: Results from a real word setting

https://doi.org/10.18632/oncotarget.16982
69025-69037
Abstract  |  PDF  |  Full Text  |  How to cite

Comparison of chemoradiotherapy with radiotherapy alone for “biopsy only” anaplastic astrocytoma

https://doi.org/10.18632/oncotarget.17441
69038-69046
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Reviews

Immunological consequences of ageing microvascular hemodynamic changes in view of cancer development and treatment

https://doi.org/10.18632/oncotarget.17749
69047-69061
Abstract  |  PDF  |  Full Text  |  How to cite

A review of the postoperative lymphatic leakage

https://doi.org/10.18632/oncotarget.17297
69062-69075
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PRAS40 signaling in tumor

https://doi.org/10.18632/oncotarget.17299
69076-69085
Abstract  |  PDF  |  Full Text  |  How to cite

Noncoding RNA in drug resistant sarcoma

https://doi.org/10.18632/oncotarget.19029
69086-69104
Abstract  |  PDF  |  Full Text  |  How to cite

PolyADPribosepolymerase inhibitors as radiosensitizers: a systematic review of preclinical and clinical human studies

https://doi.org/10.18632/oncotarget.19079
69105-69124
Abstract  |  PDF  |  Full Text  |  How to cite

Prognostic role of miR1792 family in human cancers: evaluation of multiple prognostic outcomes

https://doi.org/10.18632/oncotarget.19096
69125-69138
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The roles of signal transducer and activator of transcription factor 3 in tumor angiogenesis

https://doi.org/10.18632/oncotarget.19932
69139-69161
Abstract  |  PDF  |  Full Text  |  How to cite

Nonblood circulating tumor DNA detection in cancer

https://doi.org/10.18632/oncotarget.19942
69162-69173
Abstract  |  PDF  |  Full Text  |  How to cite

Long noncoding RNAs associated with nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.20088
69174-69184
Abstract  |  PDF  |  Full Text  |  How to cite

Culture conditions defining glioblastoma cells behavior: what is the impact for novel discoveries

https://doi.org/10.18632/oncotarget.20193
69185-69197
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite


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