Editorial

PINK1 and Ataxin2 as modifiers of growth	PINK1 and Ataxin2 as modifiers of growth
https://doi.org/10.18632/oncotarget.16636 Nesli E. Sen, Suzana Gispert, and Georg Auburger
32382-32383

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Research Papers: Pathology

Activityinduced spontaneous spikes in GABAergic neurons suppress seizure discharges: an implication of computational modeling	Activityinduced spontaneous spikes in GABAergic neurons suppress seizure discharges: an implication of computational modeling
https://doi.org/10.18632/oncotarget.15660 Wei Lu, Jing Feng, Bo Wen, Kewei Wang, and Jin-Hui Wang
32384-32397

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A polymorphism at IGF1 locus is associated with anemia	A polymorphism at IGF1 locus is associated with anemia
https://doi.org/10.18632/oncotarget.16132 Maria Adelaide Marini, Gaia Chiara Mannino, Teresa Vanessa Fiorentino, Francesco Andreozzi, Francesco Perticone, and Giorgio Sesti
32398-32406

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Research Papers: Immunology

IL33/ST2mediated inflammation in macrophages is directly abrogated by IL10 during rheumatoid arthritis	IL33/ST2mediated inflammation in macrophages is directly abrogated by IL10 during rheumatoid arthritis
https://doi.org/10.18632/oncotarget.16299 Si Chen, Bingni Chen, Zhongyang Wen, Zhong Huang, and Liang Ye
32407-32418

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Research Papers: Autophagy and Cell Death

PreImplantation factor PIF protects cultured embryos against oxidative stress: relevance for recurrent pregnancy loss RPL therapy	PreImplantation factor PIF protects cultured embryos against oxidative stress: relevance for recurrent pregnancy loss RPL therapy
https://doi.org/10.18632/oncotarget.16028 Lindsay F. Goodale, Soren Hayrabedyan, Krassimira Todorova, Roumen Roussev, Sivakumar Ramu, Christopher Stamatkin, Carolyn B. Coulam, Eytan R. Barnea, and Robert O. Gilbert
32419-32432

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Research Papers: Neuroscience

Ketamine administered pregnant rats impair learning and memory in offspring via the CREB pathway	Ketamine administered pregnant rats impair learning and memory in offspring via the CREB pathway
https://doi.org/10.18632/oncotarget.15405 Xinran Li, Cen Guo, Yanan Li, Lina Li, Yuxin Wang, Yiming Zhang, Yue Li, Yu Chen, Wenhan Liu, and Li Gao
32433-32449

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Research Papers

Construction of an immunotoxin HN3mPE24 targeting glypican3 for liver cancer therapy	Construction of an immunotoxin HN3mPE24 targeting glypican3 for liver cancer therapy
https://doi.org/10.18632/oncotarget.10592 Chunguang Wang, Wei Gao, Mingqian Feng, Ira Pastan, and Mitchell Ho
32450-32460

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BRCA1 controls the cell division axis and governs ploidy and phenotype in human mammary cells	BRCA1 controls the cell division axis and governs ploidy and phenotype in human mammary cells
https://doi.org/10.18632/oncotarget.15688 Zhengcheng He, Nagarajan Kannan, Oksana Nemirovsky, Helen Chen, Marisa Connell, Brian Taylor, Jihong Jiang, Linda M. Pilarski, Markus C. Fleisch, Dieter Niederacher, Miguel Angel Pujana, Connie J. Eaves, and Christopher A. Maxwell
32461-32475

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Increased B cell activation is present in JAK2V617Fmutated CALRmutated and triplenegative essential thrombocythemia	Increased B cell activation is present in JAK2V617Fmutated CALRmutated and triplenegative essential thrombocythemia
https://doi.org/10.18632/oncotarget.16381 Ken-Hong Lim, Caleb Gon-Shen Chen, Yu-Cheng Chang, Yi-Hao Chiang, Chen-Wei Kao, Wei-Ting Wang, Chiao-Yi Chang, Ling Huang, Ching-Sung Lin, Chun-Chia Cheng, Hung-I Cheng, Nai-Wen Su, Johnson Lin, Yi-Fang Chang, Ming-Chih Chang, Ruey-Kuen Hsieh, Huan-Chau Lin, and Yuan-Yeh Kuo
32476-32491

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New transcriptionalbased insights into the pathogenesis of desmoplastic small round cell tumors DSRCTs	New transcriptionalbased insights into the pathogenesis of desmoplastic small round cell tumors DSRCTs
https://doi.org/10.18632/oncotarget.16477 Tiziana Negri, Silvia Brich, Fabio Bozzi, Chiara V. Volpi, Ambra V. Gualeni, Silvia Stacchiotti, Loris De Cecco, Silvana Canevari, Annunziata Gloghini, and Silvana Pilotti
32492-32504

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Galectin1 expression imprints a neurovascular phenotype in proliferative retinopathies and delineates responses to antiVEGF	Galectin1 expression imprints a neurovascular phenotype in proliferative retinopathies and delineates responses to antiVEGF
https://doi.org/10.18632/oncotarget.17129 Magali E. Ridano, Paula V. Subirada, María C. Paz, Valeria E. Lorenc, Juan C. Stupirski, Ana L. Gramajo, José D. Luna, Diego O. Croci, Gabriel A. Rabinovich, and María C. Sánchez
32505-32522

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Midkine promotes hepatocellular carcinoma metastasis by elevating anoikis resistance of circulating tumor cells	Midkine promotes hepatocellular carcinoma metastasis by elevating anoikis resistance of circulating tumor cells
https://doi.org/10.18632/oncotarget.15808 Bin Sun, Congli Hu, Zhibin Yang, Xiaofeng Zhang, Linlin Zhao, Junye Xiong, Junyong Ma, Lei Chen, Haihua Qian, Xiangji Luo, Lehua Shi, Jun Li, Xianshuo Cheng, and Zhengfeng Yin
32523-32535

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Immunotherapeutic target expression on breast tumors can be amplified by hormone receptor antagonism: a novel strategy for enhancing efficacy of targeted immunotherapy	Immunotherapeutic target expression on breast tumors can be amplified by hormone receptor antagonism: a novel strategy for enhancing efficacy of targeted immunotherapy
https://doi.org/10.18632/oncotarget.15812 Ritika Jaini, Matthew G. Loya, and Charis Eng
32536-32549

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Highdose ascorbate and arsenic trioxide selectively kill acute myeloid leukemia and acute promyelocytic leukemia blasts in vitro	Highdose ascorbate and arsenic trioxide selectively kill acute myeloid leukemia and acute promyelocytic leukemia blasts in vitro
https://doi.org/10.18632/oncotarget.15925 Nélida I. Noguera, Elvira Pelosi, Daniela F. Angelini, Maria Liliana Piredda, Gisella Guerrera, Eleonora Piras, Luca Battistini, Lauretta Massai, Anna Berardi, Gianfranco Catalano, Laura Cicconi, Germana Castelli, Agnese D’Angiò, Luca Pasquini, Grazia Graziani, Giuseppe Fioritoni, Maria Teresa Voso, Domenico Mastrangelo, Ugo Testa, and Francesco Lo-Coco
32550-32565

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miR29a regulated ERpositive breast cancer cell growth and invasion and is involved in the insulin signaling pathway	miR29a regulated ERpositive breast cancer cell growth and invasion and is involved in the insulin signaling pathway
https://doi.org/10.18632/oncotarget.15928 Zhi-hua Li, Qiu-yun Xiong, Liang Xu, Peng Duan, Qianwen Ou Yang, Ping Zhou, and Jian-hong Tu
32566-32575

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NADPH accumulation is responsible for apoptosis in breast cancer cells induced by fatty acid synthase inhibition	NADPH accumulation is responsible for apoptosis in breast cancer cells induced by fatty acid synthase inhibition
https://doi.org/10.18632/oncotarget.15936 Yanfen Cui, Pan Xing, Yuanyuan Wang, Miao Liu, Li Qiu, Guoguang Ying, and Binghui Li
32576-32585

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Deguelin inhibits nonsmall cell lung cancer via downregulating Hexokinases IImediated glycolysis	Deguelin inhibits nonsmall cell lung cancer via downregulating Hexokinases IImediated glycolysis
https://doi.org/10.18632/oncotarget.15937 Wei Li, Feng Gao, Xiaoqian Ma, Ruike Wang, Xin Dong, and Wei Wang
32586-32599

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Histopathologic tumor invasion of superior mesenteric vein/ portal vein is a poor prognostic indicator in patients with pancreatic ductal adenocarcinoma: results from a systematic review and metaanalysis	Histopathologic tumor invasion of superior mesenteric vein/ portal vein is a poor prognostic indicator in patients with pancreatic ductal adenocarcinoma: results from a systematic review and metaanalysis
https://doi.org/10.18632/oncotarget.15938 Ailin Song, Farong Liu, Lupeng Wu, Xiaoying Si, and Yanming Zhou
32600-32607

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Assessment of the interlaboratory variability and robustness of JAK2V617F mutation assays: A study involving a consortium of 19 Italian laboratories	Assessment of the interlaboratory variability and robustness of JAK2V617F mutation assays: A study involving a consortium of 19 Italian laboratories
https://doi.org/10.18632/oncotarget.15940 Margherita Perricone, Francesca Palandri, Emanuela Ottaviani, Mario Angelini, Laura Bagli, Enrica Bellesia, Meris Donati, Donato Gemmati, Patrizia Zucchini, Stefania Mancini, Valentina Marchica, Serena Trubini, Giovanna De Matteis, Silvia Di Zacomo, Mosè Favarato, Annamaria Fioroni, Caterina Bolzonella, Giorgia Maccari, Filippo Navaglia, Daniela Gatti, Luisa Toffolatti, Linda Orlandi, Vèronique Laloux, Marco Manfrini, Piero Galieni, Barbara Giannini, Alessia Tieghi, Sara Barulli, Maria Luisa Serino, Monica Maccaferri, Anna Rita Scortechini, Nicola Giuliani, Daniele Vallisa, Massimiliano Bonifacio, Patrizia Accorsi, Cristina Salbe, Vinicio Fazio, Milena Gusella, Eleonora Toffoletti, Marzia Salvucci, Mirija Svaldi, Filippo Gherlinzoni, Francesca Cassavia, Francesco Orsini, and Giovanni Martinelli
32608-32617

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Diversity of the association of serum levels and genetic variants of MHC class I polypeptiderelated chain A with liver fibrosis in chronic hepatitis C	Diversity of the association of serum levels and genetic variants of MHC class I polypeptiderelated chain A with liver fibrosis in chronic hepatitis C
https://doi.org/10.18632/oncotarget.15941 Chung-Feng Huang, Ching-I Huang, Ming-Lun Yeh, Shu-Chi Wang, Kuan-Yu Chen, Yu-Min Ko, Ching-Chih Lin, Yi-Shan Tsai, Pei-Chien Tsai, Zu-Yau Lin, Shinn-Cherng Chen, Chia-Yen Dai, Jee-Fu Huang, Wan-Long Chuang, and Ming-Lung Yu
32618-32625

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Clinical features and treatment outcome of nonsmall cell lung cancer NSCLC patients with uncommon or complex epidermal growth factor receptor EGFR mutations	Clinical features and treatment outcome of nonsmall cell lung cancer NSCLC patients with uncommon or complex epidermal growth factor receptor EGFR mutations
https://doi.org/10.18632/oncotarget.15945 Stefano Frega, Martina Lorenzi, Matteo Fassan, Stefano Indraccolo, Fiorella Calabrese, Adolfo Favaretto, Laura Bonanno, Valentina Polo, Giulia Zago, Francesca Lunardi, Ilaria Attili, Alberto Pavan, Massimo Rugge, Valentina Guarneri, PierFranco Conte, and Giulia Pasello
32626-32638

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UBE2T knockdown inhibits gastric cancer progression	UBE2T knockdown inhibits gastric cancer progression
https://doi.org/10.18632/oncotarget.15947 Changjiang Luo, Yunyi Yao, Zeyuan Yu, Huinian Zhou, Lingyun Guo, Junqiang Zhang, Hongtai Cao, Genyuan Zhang, Yumin Li, and Zuoyi Jiao
32639-32654

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EGFR inhibition attenuates diabetic nephropathy through decreasing ROS and endoplasmic reticulum stress	EGFR inhibition attenuates diabetic nephropathy through decreasing ROS and endoplasmic reticulum stress
https://doi.org/10.18632/oncotarget.15948 Zheng Xu, Yunjie Zhao, Peng Zhong, Jingying Wang, Qiaoyou Weng, Yuanyuan Qian, Jibo Han, Chunpeng Zou, and Guang Liang
32655-32667

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Epidermal growth factor receptor variant III in head and neck squamous cell carcinoma is not relevant for targeted therapy and irradiation	Epidermal growth factor receptor variant III in head and neck squamous cell carcinoma is not relevant for targeted therapy and irradiation
https://doi.org/10.18632/oncotarget.15949 Dominik Thomas Koch, Anja Pickhard, Lena Gebel, Anna Maria S. Buchberger, Murat Bas, Carolin Mogler, Rudolf Reiter, Guido Piontek, and Markus Wirth
32668-32682

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USP22 drives colorectal cancer invasion and metastasis via epithelialmesenchymal transition by activating AP4	USP22 drives colorectal cancer invasion and metastasis via epithelialmesenchymal transition by activating AP4
https://doi.org/10.18632/oncotarget.15950 Yongmin Li, Yanmei Yang, Jingwen Li, He Liu, Fuxun Chen, Bingyang Li, Binbin Cui, and Yanlong Liu
32683-32695

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Long intergenic noncoding RNA 00673 promotes nonsmallcell lung cancer metastasis by binding with EZH2 and causing epigenetic silencing of HOXA5	Long intergenic noncoding RNA 00673 promotes nonsmallcell lung cancer metastasis by binding with EZH2 and causing epigenetic silencing of HOXA5
https://doi.org/10.18632/oncotarget.16158 Chenhui Ma, Guannan Wu, Qingqing Zhu, Hongbing Liu, Yanwen Yao, Dongmei Yuan, Yafang Liu, Tangfeng Lv, and Yong Song
32696-32705

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High mobility group box 1 antagonist limits metastatic seeding in the lungs via reduction of cell–cell adhesion	High mobility group box 1 antagonist limits metastatic seeding in the lungs via reduction of cell–cell adhesion
https://doi.org/10.18632/oncotarget.16188 Adi Karsch-Bluman, Benzion Amoyav, Nethanel Friedman, Hila Shoval, Ouri Schwob, Ofra Benny, Ori Wald, and Ofra Benny
32706-32721

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Tumorderived IL18 induces PD1 expression on immunosuppressive NK cells in triplenegative breast cancer	Tumorderived IL18 induces PD1 expression on immunosuppressive NK cells in triplenegative breast cancer
https://doi.org/10.18632/oncotarget.16281 In Hae Park, Han Na Yang, Kyoung Joo Lee, Tae-Sik Kim, Eun Sook Lee, So-Youn Jung, Youngmee Kwon, and Sun-Young Kong
32722-32730

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Prognostic roles of Notch receptor mRNA expression in human ovarian cancer	Prognostic roles of Notch receptor mRNA expression in human ovarian cancer
https://doi.org/10.18632/oncotarget.16387 Chuan Chen, Xiaojiao Wang, Shunping Huang, Lin Wang, Lili Han, and Songtao Yu
32731-32740

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Theranostic imaging of liver cancer using targeted optical/MRI dualmodal probes	Theranostic imaging of liver cancer using targeted optical/MRI dualmodal probes
https://doi.org/10.18632/oncotarget.15642 Qingshan Chen, Wenting Shang, Chaoting Zeng, Kun Wang, Xiaoyuan Liang, Chongwei Chi, Xiao Liang, Jian Yang, Chihua Fang, and Jie Tian
32741-32751

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Uncoupling genotoxic stress responses from circadian control increases susceptibility to mammary carcinogenesis	Uncoupling genotoxic stress responses from circadian control increases susceptibility to mammary carcinogenesis
https://doi.org/10.18632/oncotarget.15678 Mingzhu Fang, Pamela A. Ohman Strickland, Hwan-Goo Kang, and Helmut Zarbl
32752-32768

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microRNA200c/141 upregulates SerpinB2 to promote breast cancer cell metastasis and reduce patient survival	microRNA200c/141 upregulates SerpinB2 to promote breast cancer cell metastasis and reduce patient survival
https://doi.org/10.18632/oncotarget.15680 Tiefeng Jin, Hoe Suk Kim, Sul Ki Choi, Eun Hye Hwang, Jisu Woo, Han Suk Ryu, Kwangsoo Kim, Aree Moon, and Woo Kyung Moon
32769-32782

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MMP11 promoted the oral cancer migration and FAK/Src activation	MMP11 promoted the oral cancer migration and FAK/Src activation
https://doi.org/10.18632/oncotarget.15824 Chung-Han Hsin, Ying-Erh Chou, Shun-Fa Yang, Shih-Chi Su, Yi-Ting Chuang, Shu-Hui Lin, and Chiao-Wen Lin
32783-32793

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Metformin inhibits ALK1mediated angiogenesis via activation of AMPK	Metformin inhibits ALK1mediated angiogenesis via activation of AMPK
https://doi.org/10.18632/oncotarget.15825 Ying Ying, Takashi Ueta, Shanshan Jiang, Hui Lin, Yuanyuan Wang, Demetrios Vavvas, Rong Wen, Ye-Guang Chen, and Zhijun Luo
32794-32806

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Coroglaucigenin enhances the radiosensitivity of human lung cancer cells through Nrf2/ROS pathway	Coroglaucigenin enhances the radiosensitivity of human lung cancer cells through Nrf2/ROS pathway
https://doi.org/10.18632/oncotarget.16454 Meng Sun, Dong Pan, Yaxiong Chen, Ya Li, Kun Gao, and Burong Hu
32807-32820

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Identification of DBCCR1 as a suppressor in the development of lung cancer that is associated with increased DNA methyltransferase 1	Identification of DBCCR1 as a suppressor in the development of lung cancer that is associated with increased DNA methyltransferase 1
https://doi.org/10.18632/oncotarget.15826 Guoren Zhou, Jinjun Ye, Ying Fang, Zhi Zhang, Jingyuan Zhang, Lei Sun, and Jifeng Feng
32821-32832

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KPNB1mediated nuclear import is required for motility and inflammatory transcription factor activity in cervical cancer cells	KPNB1mediated nuclear import is required for motility and inflammatory transcription factor activity in cervical cancer cells
https://doi.org/10.18632/oncotarget.15834 Tamara Stelma, and Virna D. Leaner
32833-32847

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Hormone receptor expression profiles differ between primary and recurrent highgrade serous ovarian cancers	Hormone receptor expression profiles differ between primary and recurrent highgrade serous ovarian cancers
https://doi.org/10.18632/oncotarget.15858 Zheng Feng, Hao Wen, Xingzhu Ju, Rui Bi, Xiaojun Chen, Wentao Yang, and Xiaohua Wu
32848-32855

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AH1N1pdm09 influenza infection: vaccine inefficiency	AH1N1pdm09 influenza infection: vaccine inefficiency
https://doi.org/10.18632/oncotarget.16459 Nehemya Friedman, Yaron Drori, Rakefet Pando, Aharona Glatman-Freedman, Hanna Sefty, Ravit Bassal, Yaniv Stein, Tamy Shohat, Ella Mendelson, Musa Hindiyeh, and Michal Mandelboim
32856-32863

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ROR1 expression as a biomarker for predicting prognosis in patients with colorectal cancer	ROR1 expression as a biomarker for predicting prognosis in patients with colorectal cancer
https://doi.org/10.18632/oncotarget.15860 Jian-Kang Zhou, Yu-Zhu Zheng, Xue-Sha Liu, Qiheng Gou, Rui Ma, Cheng-Lin Guo, Carlo M. Croce, Lunxu Liu, and Yong Peng
32864-32872

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Hypoxia activates placental growth factor expression in lymphatic endothelial cells	Hypoxia activates placental growth factor expression in lymphatic endothelial cells
https://doi.org/10.18632/oncotarget.15861 Laura Tudisco, Augusto Orlandi, Valeria Tarallo, and Sandro De Falco
32873-32883

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Combinatorial treatment with polyI:C and antiIL6 enhances apoptosis and suppresses metastasis of lung cancer cells	Combinatorial treatment with polyI:C and antiIL6 enhances apoptosis and suppresses metastasis of lung cancer cells
https://doi.org/10.18632/oncotarget.15862 Wai Hoe Lau, Xiphias Ge Zhu, Shamaine Wei Ting Ho, Shu Chun Chang, and Jeak Ling Ding
32884-32904

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LncRNA HOTAIR acts as competing endogenous RNA to control the expression of Notch3 via sponging miR613 in pancreatic cancer	LncRNA HOTAIR acts as competing endogenous RNA to control the expression of Notch3 via sponging miR613 in pancreatic cancer
https://doi.org/10.18632/oncotarget.16462 Huihua Cai, Jie Yao, Yong An, Xuemin Chen, Weibo Chen, Di Wu, Boyang Luo, Yong Yang, Yong Jiang, Donglin Sun, and Xiaozhou He
32905-32917

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A phase 2 study of vorinostat in locally advanced recurrent or metastatic adenoid cystic carcinoma	A phase 2 study of vorinostat in locally advanced recurrent or metastatic adenoid cystic carcinoma
https://doi.org/10.18632/oncotarget.16464 Priscila H. Goncalves, Lance K. Heilbrun, Michael T. Barrett, Shivaani Kummar, Aaron R. Hansen, Lillian L. Siu, Richard L. Piekarz, Ammar W. Sukari, Joseph Chao, Mary Jo Pilat, Daryn W. Smith, Lindsay Casetta, Scott A. Boerner, Alice Chen, Elizabeth Lenkiewicz, Smriti Malasi, and Patricia M. LoRusso
32918-32929

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Characteristics of prostate cancer detection rate PCDR in Chinese Han population under different prostate biopsy methods	Characteristics of prostate cancer detection rate PCDR in Chinese Han population under different prostate biopsy methods
https://doi.org/10.18632/oncotarget.16512 Yongsheng Pan, Bianjiang Liu, Yuan Huang, Jun Wang, Xiao Li, Cheng Zhang, Jie Wu, Yuxiao Zheng, Chao Qin, Gong Cheng, Lixin Hua, and Zengjun Wang
32930-32936

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Huaier aqueous extract protects against dextran sulfate sodiuminduced experimental colitis in mice by inhibiting NLRP3 inflammasome activation	Huaier aqueous extract protects against dextran sulfate sodiuminduced experimental colitis in mice by inhibiting NLRP3 inflammasome activation
https://doi.org/10.18632/oncotarget.16513 Lijuan Wang, Zhongxia Yu, Chao Wei, Li Zhang, Hui Song, Bing Chen, and Qifeng Yang
32937-32945

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Glucose availability controls ATF4mediated MITF suppression to drive melanoma cell growth	Glucose availability controls ATF4mediated MITF suppression to drive melanoma cell growth
https://doi.org/10.18632/oncotarget.16514 Jennifer Ferguson, Michael Smith, Isabel Zudaire, Claudia Wellbrock, and Imanol Arozarena
32946-32959

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Penfluridol suppresses glioblastoma tumor growth by Aktmediated inhibition of GLI1	Penfluridol suppresses glioblastoma tumor growth by Aktmediated inhibition of GLI1
https://doi.org/10.18632/oncotarget.16515 Alok Ranjan, and Sanjay K. Srivastava
32960-32976

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Ccl5 establishes an autocrine highgrade glioma growth regulatory circuit critical for mesenchymal glioblastoma survival	Ccl5 establishes an autocrine highgrade glioma growth regulatory circuit critical for mesenchymal glioblastoma survival
https://doi.org/10.18632/oncotarget.16516 Yuan Pan, Laura J. Smithson, Yu Ma, Dolores Hambardzumyan, and David H. Gutmann
32977-32989

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Novel RNA biomarkers of prostate cancer revealed by RNAseq analysis of formalinfixed samples obtained from Russian patients	Novel RNA biomarkers of prostate cancer revealed by RNAseq analysis of formalinfixed samples obtained from Russian patients
https://doi.org/10.18632/oncotarget.16518 Anastasia S. Nikitina, Elena I. Sharova, Svetlana A. Danilenko, Tatiana B. Butusova, Alexandr O. Vasiliev, Alexandr V. Govorov, Elena A. Prilepskaya, Dmitry Y. Pushkar, and Elena S. Kostryukova
32990-33001

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The relationship between members of the canonical NFκB pathway components of tumour microenvironment and survival in patients with invasive ductal breast cancer	The relationship between members of the canonical NFκB pathway components of tumour microenvironment and survival in patients with invasive ductal breast cancer
https://doi.org/10.18632/oncotarget.16031 Lindsay Bennett, Elizabeth A. Mallon, Paul G. Horgan, Andrew Paul, Donald C. McMillan, and Joanne Edwards
33002-33013

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Patients with uterine leiomyoma exhibit a high incidence but low mortality rate for breast cancer	Patients with uterine leiomyoma exhibit a high incidence but low mortality rate for breast cancer
https://doi.org/10.18632/oncotarget.16520 Te-Chun Shen, Te-Chun Hsia, Chieh-Lun Hsiao, Cheng-Li Lin, Chih-Yi Yang, Khay-Seng Soh, Liang-Chih Liu, Wen-Shin Chang, Chia-Wen Tsai, and Da-Tian Bau
33014-33023

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Enhanced antitumor therapeutic efficacy of DNA vaccine by fusing the E7 gene to BAFF in treating human papillomavirusassociated cancer	Enhanced antitumor therapeutic efficacy of DNA vaccine by fusing the E7 gene to BAFF in treating human papillomavirusassociated cancer
https://doi.org/10.18632/oncotarget.16032 Chao-Chih Wu, Fang-Cih Wu, Yun-Tin Hsu, Yu-Chia Hsiao, Yuh-Cheng Yang, C. Allen Chang, and Chih-Long Chang
33024-33036

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Metallothionein 1M suppresses tumorigenesis in hepatocellular carcinoma	Metallothionein 1M suppresses tumorigenesis in hepatocellular carcinoma
https://doi.org/10.18632/oncotarget.16521 Cheng-Lin Fu, Bing Pan, Ju-Hua Pan, and Mei-Fu Gan
33037-33046

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iNOSderived nitric oxide promotes glycolysis by inducing pyruvate kinase M2 nuclear translocation in ovarian cancer	iNOSderived nitric oxide promotes glycolysis by inducing pyruvate kinase M2 nuclear translocation in ovarian cancer
https://doi.org/10.18632/oncotarget.16523 Linlin Li, Lingqun Zhu, Bingtao Hao, Wenwen Gao, Qianli Wang, Keyi Li, Meng Wang, Mengqiu Huang, Zhengjun Liu, Qiaohong Yang, Xiqing Li, Zhuo Zhong, Wenhua Huang, Guanghui Xiao, Yang Xu, Kaitai Yao, and Qiuzhen Liu
33047-33063

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MiR145 negatively regulates Warburg effect by silencing KLF4 and PTBP1 in bladder cancer cells	MiR145 negatively regulates Warburg effect by silencing KLF4 and PTBP1 in bladder cancer cells
https://doi.org/10.18632/oncotarget.16524 Koichiro Minami, Kohei Taniguchi, Nobuhiko Sugito, Yuki Kuranaga, Teruo Inamoto, Kiyoshi Takahara, Tomoaki Takai, Yuki Yoshikawa, Satoshi Kiyama, Yukihiro Akao, and Haruhito Azuma
33064-33077

Abstract  |  PDF  |  Full Text  |  How to cite

Classification of pediatric acute myeloid leukemia based on miRNA expression profiles	Classification of pediatric acute myeloid leukemia based on miRNA expression profiles
https://doi.org/10.18632/oncotarget.16525 Askar Obulkasim, Jenny E. Katsman-Kuipers, Lonneke Verboon, Mathijs Sanders, Ivo Touw, Mojca Jongen-Lavrencic, Rob Pieters, Jan-Henning Klusmann, C. Michel Zwaan, Marry M. van den Heuvel-Eibrink, and Maarten Fornerod
33078-33085

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

NELL1 whose high expression correlates with negative outcomes has different methylation patterns in alveolar and embryonal rhabdomyosarcoma	NELL1 whose high expression correlates with negative outcomes has different methylation patterns in alveolar and embryonal rhabdomyosarcoma
https://doi.org/10.18632/oncotarget.16526 Lucia Tombolan, Elena Poli, Paolo Martini, Angelica Zin, Chiara Romualdi, Gianni Bisogno, and Gerolamo Lanfranchi
33086-33099

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

DNA methylation profiling identifies the HOXA11 gene as an early diagnostic and prognostic molecular marker in human lung adenocarcinoma	DNA methylation profiling identifies the HOXA11 gene as an early diagnostic and prognostic molecular marker in human lung adenocarcinoma
https://doi.org/10.18632/oncotarget.16528 Qun Li, Chang Chen, Xiaohui Ren, and Weihong Sun
33100-33109

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

NID1 a new regulator of EMT required for metastasis and chemoresistance of ovarian cancer cells	NID1 a new regulator of EMT required for metastasis and chemoresistance of ovarian cancer cells
https://doi.org/10.18632/oncotarget.16145 Ya Zhou, Yuanyuan Zhu, Xiaoyan Fan, Chundong Zhang, Yitao Wang, Lian Zhang, Huan Zhang, Tao Wen, Kaina Zhang, Xiao Huo, Xue Jiang, Youquan Bu, and Ying Zhang
33110-33121

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Monoglyceride lipase deficiency affects hepatic cholesterol metabolism and lipiddependent gut transit in ApoE−/− mice	Monoglyceride lipase deficiency affects hepatic cholesterol metabolism and lipiddependent gut transit in ApoE−/− mice
https://doi.org/10.18632/oncotarget.16529 Nemanja Vujic, Melanie Korbelius, Christina Leopold, Madalina Duta-Mare, Silvia Rainer, Stefanie Schlager, Madeleine Goeritzer, Dagmar Kolb, Thomas O. Eichmann, Clemens Diwoky, Andreas Zimmer, Robert Zimmermann, Achim Lass, Branislav Radovic, and Dagmar Kratky
33122-33136

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Upregulation of long noncoding RNA HOXAAS2 promotes proliferation and induces epithelialmesenchymal transition in gallbladder carcinoma	Upregulation of long noncoding RNA HOXAAS2 promotes proliferation and induces epithelialmesenchymal transition in gallbladder carcinoma
https://doi.org/10.18632/oncotarget.16561 Peng Zhang, Peihua Cao, Xiaofeng Zhu, Mingxin Pan, Kebo Zhong, Rui He, Yang Li, Xingyuan Jiao, and Yi Gao
33137-33143

Abstract  |  PDF  |  Full Text  |  How to cite

Long noncoding RNA ROR regulates chemoresistance in docetaxelresistant lung adenocarcinoma cells via epithelial mesenchymal transition pathway	Long noncoding RNA ROR regulates chemoresistance in docetaxelresistant lung adenocarcinoma cells via epithelial mesenchymal transition pathway
https://doi.org/10.18632/oncotarget.16562 Yan Pan, Jing Chen, Leilei Tao, Kai Zhang, Rui Wang, Xiaoyuan Chu, and Longbang Chen
33144-33158

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Preferential accumulation of regulatory T cells with highly immunosuppressive characteristics in breast tumor microenvironment	Preferential accumulation of regulatory T cells with highly immunosuppressive characteristics in breast tumor microenvironment
https://doi.org/10.18632/oncotarget.16565 Azharuddin Sajid Syed Khaja, Salman M. Toor, Haytham El Salhat, Issam Faour, Navid Ul Haq, Bassam R. Ali, and Eyad Elkord
33159-33171

Abstract  |  PDF  |  Full Text  |  How to cite

Transcriptional regulation of mixed lineage kinase 3 by estrogen and its implication in ERpositive breast cancer pathogenesis	Transcriptional regulation of mixed lineage kinase 3 by estrogen and its implication in ERpositive breast cancer pathogenesis
https://doi.org/10.18632/oncotarget.16566 Navin Viswakarma, Rakesh Sathish Nair, Gautam Sondarva, Subhasis Das, Lucas Ibrahimi, Zhiyong Chen, Subhash Sinha, Basabi Rana, and Ajay Rana
33172-33184

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Poor efficacy response to trastuzumab therapy in advanced gastric cancer with homogeneous HER2 positive and nonintestinal type	Poor efficacy response to trastuzumab therapy in advanced gastric cancer with homogeneous HER2 positive and nonintestinal type
https://doi.org/10.18632/oncotarget.16567 Chen Xu, Yalan Liu, Dongxian Jiang, Qian Li, Xiaowen Ge, Ying Zhang, Jie Huang, Jieakesu Su, Yuan Ji, Jun Hou, Shaohua Lu, Yingyong Hou, and Tianshu Liu
33185-33196

Abstract  |  PDF  |  Full Text  |  How to cite

DEADbox RNA helicase 3 modulates NFκB signal pathway by controlling the phosphorylation of PP2AC subunit	DEADbox RNA helicase 3 modulates NFκB signal pathway by controlling the phosphorylation of PP2AC subunit
https://doi.org/10.18632/oncotarget.16593 Xin Wang, Rui Wang, Miao Luo, Chen Li, Hua-Xia Wang, Chang-Chao Huan, Yu-Rong Qu, Ying Liao, and Xiang Mao
33197-33213

Abstract  |  PDF  |  Full Text  |  How to cite

CD200Fc reduces LPSinduced IL1β activation in human cervical cancer cells by modulating TLR4NFκB and NLRP3 inflammasome pathway	CD200Fc reduces LPSinduced IL1β activation in human cervical cancer cells by modulating TLR4NFκB and NLRP3 inflammasome pathway
https://doi.org/10.18632/oncotarget.16596 Aiqin He, Jia Shao, Yu Zhang, Hong Lu, Zhijun Wu, and Yunzhao Xu
33214-33224

Abstract  |  PDF  |  Full Text  |  How to cite

The design of novel inhibitors for treating cancer by targeting CDC25B through disruption of CDC25BCDK2/Cyclin A interaction using computational approaches	The design of novel inhibitors for treating cancer by targeting CDC25B through disruption of CDC25BCDK2/Cyclin A interaction using computational approaches
https://doi.org/10.18632/oncotarget.16600 Hong-Lian Li, Ying Ma, Ying Ma, Yu Li, Xiu-Bo Chen, Wei-Li Dong, and Run-Ling Wang
33225-33240

Abstract  |  PDF  |  Full Text  |  How to cite

DNA plasmid vaccine carrying Chlamydia trachomatis Ct major outer membrane and human papillomavirus 16L2 proteins for antiCt infection	DNA plasmid vaccine carrying Chlamydia trachomatis Ct major outer membrane and human papillomavirus 16L2 proteins for antiCt infection
https://doi.org/10.18632/oncotarget.16601 Ledan Wang, Yiqi Cai, Yirong Xiong, Wangqi Du, Danwei Cen, Chanqiong Zhang, Yiling Song, Shanli Zhu, Xiangyang Xue, and Lifang Zhang
33241-33251

Abstract  |  PDF  |  Full Text  |  How to cite

Magnesium isoglycyrrhizinate shows hepatoprotective effects in a cyclophosphamideinduced model of hepatic injury	Magnesium isoglycyrrhizinate shows hepatoprotective effects in a cyclophosphamideinduced model of hepatic injury
https://doi.org/10.18632/oncotarget.16629 Wenjiao Jiang, Jingyan Liu, Peijin Li, Qianfeng Lu, Xue Pei, Yilin Sun, Guangji Wang, and Kun Hao
33252-33264

Abstract  |  PDF  |  Full Text  |  How to cite

Correlated high expression of FXR and Sp1 in cancer cells confers a poor prognosis for pancreatic cancer: A study based on TCGA and tissue microarray	Correlated high expression of FXR and Sp1 in cancer cells confers a poor prognosis for pancreatic cancer: A study based on TCGA and tissue microarray
https://doi.org/10.18632/oncotarget.16633 Hai Hu, Lei-Lei Wu, Ting Han, Meng Zhuo, Wang Lei, Jiu-Jie Cui, Feng Jiao, and Li-Wei Wang
33265-33275

Abstract  |  PDF  |  Full Text  |  How to cite

Intensity modulated radiotherapy with fixed collimator jaws for locoregional leftsided breast cancer irradiation	Intensity modulated radiotherapy with fixed collimator jaws for locoregional leftsided breast cancer irradiation
https://doi.org/10.18632/oncotarget.16634 Juanqi Wang, Zhaozhi Yang, Weigang Hu, Zhi Chen, Xiaoli Yu, and Xiaomao Guo
33276-33284

Abstract  |  PDF  |  Full Text  |  How to cite

Clinical significance of the correlation between PLCE 1 and PRKCA in esophageal inflammation and esophageal carcinoma	Clinical significance of the correlation between PLCE 1 and PRKCA in esophageal inflammation and esophageal carcinoma
https://doi.org/10.18632/oncotarget.16635 Yongchen Guo, Yonghua Bao, Ming Ma, Shanshan Zhang, Yongmeng Zhang, Ming Yuan, Bing Liu, Yiqiong Yang, Wen Cui, Emmanuel Ansong, Huali Dong, Virgilia Macias, and Wancai Yang
33285-33299

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

IGF1R depletion facilitates METamplification as mechanism of acquired resistance to erlotinib in HCC827 NSCLC cells	IGF1R depletion facilitates METamplification as mechanism of acquired resistance to erlotinib in HCC827 NSCLC cells
https://doi.org/10.18632/oncotarget.16350 Dianna Hussmann, Anne Tranberg Madsen, Kristine Raaby Jakobsen, Yonglun Luo, Boe Sandahl Sorensen, and Anders Lade Nielsen
33300-33315

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The p38 signaling pathway mediates quiescence of glioma stem cells by regulating epidermal growth factor receptor trafficking	The p38 signaling pathway mediates quiescence of glioma stem cells by regulating epidermal growth factor receptor trafficking
https://doi.org/10.18632/oncotarget.16741 Akio Soeda, Justin Lathia, Brian J. Williams, Qiulian Wu, Joseph Gallagher, Andreas Androutsellis-Theotokis, Amber J. Giles, Chunzhang Yang, Zhengping Zhuang, Mark R. Gilbert, Jeremy N. Rich, and Deric M. Park
33316-33328

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

USP22 maintains gastric cancer stem cell stemness and promotes gastric cancer progression by stabilizing BMI1 protein	USP22 maintains gastric cancer stem cell stemness and promotes gastric cancer progression by stabilizing BMI1 protein
https://doi.org/10.18632/oncotarget.16445 Yue Ma, Hua-Lin Fu, Zhen Wang, Hai Huang, Jian Ni, Jie Song, Ying Xia, Wei-Lin Jin, and Da-Xiang Cui
33329-33342

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Hypoxiainducible factor 1a induces phenotype switch of human aortic vascular smooth muscle cell through PI3K/AKT/AEG1 signaling	Hypoxiainducible factor 1a induces phenotype switch of human aortic vascular smooth muscle cell through PI3K/AKT/AEG1 signaling
https://doi.org/10.18632/oncotarget.16448 Kai Liu, Changcun Fang, Yuwen Shen, Zhengqin Liu, Min Zhang, Bingbing Ma, and Xinyan Pang
33343-33352

Abstract  |  PDF  |  Full Text  |  How to cite

Actin cytoskeleton regulator Arp2/3 complex is required for DLL1 activating Notch1 signaling to maintain the stem cell phenotype of glioma initiating cells	Actin cytoskeleton regulator Arp2/3 complex is required for DLL1 activating Notch1 signaling to maintain the stem cell phenotype of glioma initiating cells
https://doi.org/10.18632/oncotarget.16495 Chen Zhang, Long Hai, Meng Zhu, Shengping Yu, Tao Li, Yu Lin, Bo Liu, Xingchen Zhou, Lei Chen, Pengfei Zhao, Hua Zhou, Yubao Huang, Kai Zhang, Bingcheng Ren, and Xuejun Yang
33353-33364

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Expression of EMT markers and mode of surgery are prognostic in phyllodes tumors of the breast	Expression of EMT markers and mode of surgery are prognostic in phyllodes tumors of the breast
https://doi.org/10.18632/oncotarget.16497 Xiaolong Feng, Lin Zhao, Honghong Shen, Xiaozhen Liu, Yang Yang, Shuhua Lv, and Yun Niu
33365-33374

Abstract  |  PDF  |  Full Text  |  How to cite

Clinical significance of circulating miR253p as a novel diagnostic and prognostic biomarker in osteosarcoma	Clinical significance of circulating miR253p as a novel diagnostic and prognostic biomarker in osteosarcoma
https://doi.org/10.18632/oncotarget.16498 Tomohiro Fujiwara, Koji Uotani, Aki Yoshida, Takuya Morita, Yutaka Nezu, Eisuke Kobayashi, Akihiko Yoshida, Takenori Uehara, Toshinori Omori, Kazuhisa Sugiu, Tadashi Komatsubara, Ken Takeda, Toshiyuki Kunisada, Machiko Kawamura, Akira Kawai, Takahiro Ochiya, and Toshifumi Ozaki
33375-33392

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Imaging and targeted therapy of pancreatic ductal adenocarcinoma using the theranostic sodium iodide symporter NIS gene	Imaging and targeted therapy of pancreatic ductal adenocarcinoma using the theranostic sodium iodide symporter NIS gene
https://doi.org/10.18632/oncotarget.16499 Kathrin A. Schmohl, Aayush Gupta, Geoffrey K. Grünwald, Marija Trajkovic-Arsic, Kathrin Klutz, Rickmer Braren, Markus Schwaiger, Peter J. Nelson, Manfred Ogris, Ernst Wagner, Jens T. Siveke, and Christine Spitzweg
33393-33404

Abstract  |  PDF  |  Full Text  |  How to cite

A novel BMX variant promotes tumor cell growth and migration in lung adenocarcinoma	A novel BMX variant promotes tumor cell growth and migration in lung adenocarcinoma
https://doi.org/10.18632/oncotarget.16796 Ye Wang, Jufeng Xia, Zhaoyuan Fang, Fei Li, Duo Li, Zuoyun Wang, Yan Feng, Jian Zhang, Haiquan Chen, Hongbin Ji, and Hongyan Liu
33405-33415

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Sequential evaluation of CALR mutant burden in patients with myeloproliferative neoplasms	Sequential evaluation of CALR mutant burden in patients with myeloproliferative neoplasms
https://doi.org/10.18632/oncotarget.16797 Chiara Cavalloni, Elisa Rumi, Virginia V. Ferretti, Daniela Pietra, Elisa Roncoroni, Marta Bellini, Michele Ciboddo, Ilaria C. Casetti, Benedetta Landini, Elena Fugazza, Daniela Troletti, Cesare Astori, and Mario Cazzola
33416-33421

Abstract  |  PDF  |  Full Text  |  How to cite

C3orf21 ablation promotes the proliferation of lung adenocarcinoma and its mutation at the rs2131877 locus may serve as a susceptibility marker	C3orf21 ablation promotes the proliferation of lung adenocarcinoma and its mutation at the rs2131877 locus may serve as a susceptibility marker
https://doi.org/10.18632/oncotarget.16798 Litao Yang, Ying Wang, Meiyu Fang, Douhou Deng, and Yongjun Zhang
33422-33431

Abstract  |  PDF  |  Full Text  |  How to cite

SOCS3 treatment prevents the development of alopecia areata by inhibiting CD8+ T cellmediated autoimmune destruction	SOCS3 treatment prevents the development of alopecia areata by inhibiting CD8+ T cellmediated autoimmune destruction
https://doi.org/10.18632/oncotarget.16504 Zhen Gao, Yu-Qing Jin, and Wei Wu
33432-33443

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Fbxw7 haploinsufficiency loses its protection against DNA damage and accelerates MNUinduced gastric carcinogenesis	Fbxw7 haploinsufficiency loses its protection against DNA damage and accelerates MNUinduced gastric carcinogenesis
https://doi.org/10.18632/oncotarget.16800 Yannan Jiang, Xinming Qi, Xinyu Liu, Jun Zhang, Jun Ji, Zhenggang Zhu, Jin Ren, and Yingyan Yu
33444-33456

Abstract  |  PDF  |  Full Text  |  How to cite

The dominant role of proofreading exonuclease activity of replicative polymerase ε in cellular tolerance to cytarabine AraC	The dominant role of proofreading exonuclease activity of replicative polymerase ε in cellular tolerance to cytarabine AraC
https://doi.org/10.18632/oncotarget.16508 Masataka Tsuda, Kazuhiro Terada, Masato Ooka, Koji Kobayashi, Hiroyuki Sasanuma, Ryo Fujisawa, Toshiki Tsurimoto, Junpei Yamamoto, Shigenori Iwai, Kei Kadoda, Remi Akagawa, Shar-yin Naomi Huang, Yves Pommier, Julian E. Sale, Shunichi Takeda, and Kouji Hirota
33457-33474

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Microrna217 modulates human skin fibroblast senescence by directly targeting DNA methyltransferase 1	Microrna217 modulates human skin fibroblast senescence by directly targeting DNA methyltransferase 1
https://doi.org/10.18632/oncotarget.16509 Ben Wang, Rui Du, Xiao Xiao, Zhi-Li Deng, Dan Jian, Hong-Fu Xie, and Ji Li
33475-33486

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinical and prognostic significance of aberrant Tcell marker expression in 225 cases of de novo diffuse large Bcell lymphoma and 276 cases of other Bcell lymphomas	Clinical and prognostic significance of aberrant Tcell marker expression in 225 cases of de novo diffuse large Bcell lymphoma and 276 cases of other Bcell lymphomas
https://doi.org/10.18632/oncotarget.16532 Naoko Tsuyama, Daisuke Ennishi, Masahiro Yokoyama, Satoko Baba, Reimi Asaka, Yuko Mishima, Yasuhito Terui, Kiyohiko Hatake, and Kengo Takeuchi
33487-33500

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

IL35 induces N2 phenotype of neutrophils to promote tumor growth	IL35 induces N2 phenotype of neutrophils to promote tumor growth
https://doi.org/10.18632/oncotarget.16819 Jiu-Ming Zou, Jian Qin, Yong-Chao Li, Yu Wang, Dong Li, Yu Shu, Chao Luo, Shan-Shan Wang, Gang Chi, Fang Guo, Gui-Mei Zhang, and Zuo-Hua Feng
33501-33514

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Caspase 12 degrades IκBα protein and enhances MMP9 expression in human nasopharyngeal carcinoma cell invasion	Caspase 12 degrades IκBα protein and enhances MMP9 expression in human nasopharyngeal carcinoma cell invasion
https://doi.org/10.18632/oncotarget.16535 Wing-Keung Chu, Chih-Chin Hsu, Shiang-Fu Huang, Chia-Chi Hsu, and Shu-Er Chow
33515-33526

Abstract  |  PDF  |  Full Text  |  How to cite

Identification of STXBP2 as a novel susceptibility locus for myocardial infarction in Japanese individuals by an exomewide association study	Identification of STXBP2 as a novel susceptibility locus for myocardial infarction in Japanese individuals by an exomewide association study
https://doi.org/10.18632/oncotarget.16536 Yoshiji Yamada, Jun Sakuma, Ichiro Takeuchi, Yoshiki Yasukochi, Kimihiko Kato, Mitsutoshi Oguri, Tetsuo Fujimaki, Hideki Horibe, Masaaki Muramatsu, Motoji Sawabe, Yoshinori Fujiwara, Yu Taniguchi, Shuichi Obuchi, Hisashi Kawai, Shoji Shinkai, Seijiro Mori, Tomio Arai, and Masashi Tanaka
33527-33535

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genetic variation of long noncoding RNA TINCR contribute to the susceptibility and progression of colorectal cancer	Genetic variation of long noncoding RNA TINCR contribute to the susceptibility and progression of colorectal cancer
https://doi.org/10.18632/oncotarget.16538 Yongbin Zheng, Chao Yang, Shilun Tong, Yu Ding, Wenhong Deng, Dan Song, and Kuang Xiao
33536-33543

Abstract  |  PDF  |  Full Text  |  How to cite

Loss of Tpm41 leads to disruption of cellcell adhesions and invasive behavior in breast epithelial cells via increased Rac1 signaling	Loss of Tpm41 leads to disruption of cellcell adhesions and invasive behavior in breast epithelial cells via increased Rac1 signaling
https://doi.org/10.18632/oncotarget.16825 SukYeong Jeong, SunYoung Lim, Galina Schevzov, Peter W. Gunning, and David M. Helfman
33544-33559

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Transforming growth factor β1 promotes invasion of human JEG3 trophoblast cells via TGFβ/Smad3 signaling pathway	Transforming growth factor β1 promotes invasion of human JEG3 trophoblast cells via TGFβ/Smad3 signaling pathway
https://doi.org/10.18632/oncotarget.16826 Zhongying Huang, Shangwei Li, Wei Fan, and Qianhong Ma
33560-33570

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Utilizing combinatorial engineering to develop Tie2 targeting antagonistic angiopoetin2 ligands as candidates for antiangiogenesis therapy	Utilizing combinatorial engineering to develop Tie2 targeting antagonistic angiopoetin2 ligands as candidates for antiangiogenesis therapy
https://doi.org/10.18632/oncotarget.16827 Tomer Shlamkovich, Lidan Aharon, William A. Barton, and Niv Papo
33571-33585

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Overexpression of NOX4 predicts poor prognosis and promotes tumor progression in human colorectal cancer	Overexpression of NOX4 predicts poor prognosis and promotes tumor progression in human colorectal cancer
https://doi.org/10.18632/oncotarget.16829 Xiao-Lu Lin, Li Yang, Seng-Wang Fu, Wen-Feng Lin, Yun-Jie Gao, Hao-Yan Chen, and Zhi-Zheng Ge
33586-33600

Abstract  |  PDF  |  Full Text  |  How to cite

Effect of Salmonella enterica serovar Typhimurium VNP20009 and VNP20009 with restored chemotaxis on 4T1 mouse mammary carcinoma progression	Effect of Salmonella enterica serovar Typhimurium VNP20009 and VNP20009 with restored chemotaxis on 4T1 mouse mammary carcinoma progression
https://doi.org/10.18632/oncotarget.16830 Sheryl L. Coutermarsh-Ott, Katherine M. Broadway, Birgit E. Scharf, and Irving C. Allen
33601-33613

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Correlation of genomic alterations assessed by nextgeneration sequencing NGS of tumor tissue DNA and circulating tumor DNA ctDNA in metastatic renal cell carcinoma mRCC: potential clinical implications	Correlation of genomic alterations assessed by nextgeneration sequencing NGS of tumor tissue DNA and circulating tumor DNA ctDNA in metastatic renal cell carcinoma mRCC: potential clinical implications
https://doi.org/10.18632/oncotarget.16833 Andrew W. Hahn, David M. Gill, Benjamin Maughan, Archana Agarwal, Lubina Arjyal, Sumati Gupta, Jessica Streeter, Erin Bailey, Sumanta K. Pal, and Neeraj Agarwal
33614-33620

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR199a3p enhances cisplatin sensitivity of cholangiocarcinoma cells by inhibiting mTOR signaling pathway and expression of MDR1	MiR199a3p enhances cisplatin sensitivity of cholangiocarcinoma cells by inhibiting mTOR signaling pathway and expression of MDR1
https://doi.org/10.18632/oncotarget.16834 Qiang Li, Xuefeng Xia, Jie Ji, Jianghui Ma, Liang Tao, Linjun Mo, and Wei Chen
33621-33630

Abstract  |  PDF  |  Full Text  |  How to cite

Noninvasive prediction of the tumor growth rate using advanced diffusion models in head and neck squamous cell carcinoma patients	Noninvasive prediction of the tumor growth rate using advanced diffusion models in head and neck squamous cell carcinoma patients
https://doi.org/10.18632/oncotarget.16851 Noriyuki Fujima, Tomohiro Sakashita, Akihiro Homma, Taisuke Harada, Yukie Shimizu, Khin Khin Tha, Kohsuke Kudo, and Hiroki Shirato
33631-33643

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

FOXD3 regulates anaplastic thyroid cancer progression	FOXD3 regulates anaplastic thyroid cancer progression
https://doi.org/10.18632/oncotarget.16853 Huabin Yin, Tong Meng, Lei Zhou, Feixing Zhao, Xiufang Li, Yundong Li, Mengjun Hu, Haiyan Chen, and Dianwen Song
33644-33651

Abstract  |  PDF  |  Full Text  |  How to cite

Chronic grouped social restriction triggers longlasting immune system adaptations	Chronic grouped social restriction triggers longlasting immune system adaptations
https://doi.org/10.18632/oncotarget.16856 Rui Tian, Gonglin Hou, Liuwei Song, Jianming Zhang, and Ti-Fei Yuan
33652-33657

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Skeletal muscle measures and physical function in older adults with cancer: sarcopenia or myopenia	Skeletal muscle measures and physical function in older adults with cancer: sarcopenia or myopenia
https://doi.org/10.18632/oncotarget.16866 Grant R. Williams, Allison M. Deal, Hyman B. Muss, Marc S. Weinberg, Hanna K. Sanoff, Kirsten A. Nyrop, Mackenzi Pergolotti, and Shlomit Strulov Shachar
33658-33665

Abstract  |  PDF  |  Full Text  |  How to cite

TAK1 inhibitor 5Z7oxozeaenol sensitizes cervical cancer to doxorubicininduced apoptosis	TAK1 inhibitor 5Z7oxozeaenol sensitizes cervical cancer to doxorubicininduced apoptosis
https://doi.org/10.18632/oncotarget.16895 Shan Guan, Jiaxiong Lu, Yanling Zhao, Sarah E. Woodfield, Huiyuan Zhang, Xin Xu, Yang Yu, Jing Zhao, Shayahati Bieerkehazhi, Haoqian Liang, Jianhua Yang, Fuchun Zhang, and Surong Sun
33666-33675

Abstract  |  PDF  |  Full Text  |  How to cite

Risk factors for the recurrence of an intracranial saccular aneurysm following endovascular treatment	Risk factors for the recurrence of an intracranial saccular aneurysm following endovascular treatment
https://doi.org/10.18632/oncotarget.16897 De-Zhang Huang, Bin Jiang, Wei He, Yi-Hua Wang, and Zhi-Gang Wang
33676-33682

Abstract  |  PDF  |  Full Text  |  How to cite

Growthsuppressive activity of raloxifene on liver cancer cells by targeting IL6/GP130 signaling	Growthsuppressive activity of raloxifene on liver cancer cells by targeting IL6/GP130 signaling
https://doi.org/10.18632/oncotarget.16898 Yina Wang, Haiyan Ma, Chongqiang Zhao, Tianshu Liu, Dan Yan, David Jou, Huameng Li, Cuntai Zhang, Jiagao Lü, Chenglong Li, Jiayuh Lin, Sheng Li, and Li Lin
33683-33693

Abstract  |  PDF  |  Full Text  |  How to cite

AKR1B10 promotes breast cancer cell migration and invasion via activation of ERK signaling	AKR1B10 promotes breast cancer cell migration and invasion via activation of ERK signaling
https://doi.org/10.18632/oncotarget.16624 Jia Li, Yuanwei Guo, Lili Duan, Xinglin Hu, Xi Zhang, Jian Hu, Li Huang, Rongzhang He, Zheng Hu, Weihao Luo, Tan Tan, Renbin Huang, Duanfang Liao, Yuan-Shan Zhu, and Di-Xian Luo
33694-33703

Abstract  |  PDF  |  Full Text  |  How to cite

Ulk1 overexpression in human gastric cancer is correlated with patients' T classification and cancer relapse	Ulk1 overexpression in human gastric cancer is correlated with patients' T classification and cancer relapse
https://doi.org/10.18632/oncotarget.16734 Min-Bin Chen, Xiao-Zhi Ji, Yuan-Yuan Liu, Ping Zeng, Xin-Yu Xu, Rong Ma, Zheng-Dong Guo, Jian-Wei Lu, and Ji-Feng Feng
33704-33712

Abstract  |  PDF  |  Full Text  |  How to cite

Prognostic role of the long noncoding RNA SPRY4 Intronic Transcript 1 in patients with cancer: a metaanalysis	Prognostic role of the long noncoding RNA SPRY4 Intronic Transcript 1 in patients with cancer: a metaanalysis
https://doi.org/10.18632/oncotarget.16735 Miaojuan Wang, Xuejun Dong, Yi Feng, Honggang Sun, Ningping Shan, and Tao Lu
33713-33724

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Antagonistic effects of selenium on leadinduced autophagy by influencing mitochondrial dynamics in the spleen of chickens	Antagonistic effects of selenium on leadinduced autophagy by influencing mitochondrial dynamics in the spleen of chickens
https://doi.org/10.18632/oncotarget.16736 Yujing Han, Chunqiu Li, Mingjun Su, Zhihui Wang, Ning Jiang, and Dongbo Sun
33725-33735

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The role of metabolic tumor volume MTV measured by [18F] FDG PET/CT in predicting EGFR gene mutation status in nonsmall cell lung cancer	The role of metabolic tumor volume MTV measured by [18F] FDG PET/CT in predicting EGFR gene mutation status in nonsmall cell lung cancer
https://doi.org/10.18632/oncotarget.16806 Ao Liu, Anqin Han, Hui Zhu, Li Ma, Yong Huang, Minghuan Li, Feng Jin, Qiuan Yang, and Jinming Yu
33736-33744

Abstract  |  PDF  |  Full Text  |  How to cite

Functional analysis implicating the SNP rs61552325 in ERBB2 as an effector for androgeninsensitive prostate cancer cell invasion	Functional analysis implicating the SNP rs61552325 in ERBB2 as an effector for androgeninsensitive prostate cancer cell invasion
https://doi.org/10.18632/oncotarget.16807 Xianxiang Xin, Yinmin Gu, Yang Chen, Yuanjie Huang, Zengnan Mo, and Yanling Hu
33745-33755

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Melatonin exerts antioral cancer effect via suppressing LSD1 in patientderived tumor xenograft models	Melatonin exerts antioral cancer effect via suppressing LSD1 in patientderived tumor xenograft models
https://doi.org/10.18632/oncotarget.16808 Cheng-Yu Yang, Chih-Kung Lin, Chang-Huei Tsao, Cheng-Chih Hsieh, Gu-Jiun Lin, Kuo-Hsing Ma, Yi-Shing Shieh, Huey-Kang Sytwu, and Yuan-Wu Chen
33756-33769

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Combination analysis of NOS3 ABCB1 and IL23R polymorphisms with alcoholinduced osteonecrosis of the femoral head risk in Chinese males	Combination analysis of NOS3 ABCB1 and IL23R polymorphisms with alcoholinduced osteonecrosis of the femoral head risk in Chinese males
https://doi.org/10.18632/oncotarget.16809 Yuan Wang, Xuejun Yang, Jianping Shi, Yan Zhao, Linlin Pan, Jinqiu Zhou, Guoqiang Wang, and Jianzhong Wang
33770-33778

Abstract  |  PDF  |  Full Text  |  How to cite

SEL12034A is a novel CDK8 inhibitor active in AML cells with high levels of serine phosphorylation of STAT1 and STAT5 transactivation domains	SEL12034A is a novel CDK8 inhibitor active in AML cells with high levels of serine phosphorylation of STAT1 and STAT5 transactivation domains
https://doi.org/10.18632/oncotarget.16810 Tomasz Rzymski, Michał Mikula, Eliza Żyłkiewicz, Agnieszka Dreas, Katarzyna Wiklik, Aniela Gołas, Katarzyna Wójcik, Magdalena Masiejczyk, Anna Wróbel, Izabela Dolata, Agata Kitlińska, Małgorzata Statkiewicz, Urszula Kuklinska, Krzysztof Goryca, Łukasz Sapała, Aleksandra Grochowska, Aleksandra Cabaj, Małgorzata Szajewska-Skuta, Ewelina Gabor-Worwa, Katarzyna Kucwaj, Arkadiusz Białas, Adam Radzimierski, Michał Combik, Jakub Woyciechowski, Maciej Mikulski, Renata Windak, Jerzy Ostrowski, and Krzysztof Brzózka
33779-33795

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Antiangiogenesis and gene aberrationrelated therapy may improve overall survival in patients with concurrent KRAS and TP53 hotspot mutant cancer	Antiangiogenesis and gene aberrationrelated therapy may improve overall survival in patients with concurrent KRAS and TP53 hotspot mutant cancer
https://doi.org/10.18632/oncotarget.16840 Zhijie Wang, Sarina Piha-Paul, Filip Janku, Vivek Subbiah, Naiyi Shi, Jing Gong, Chetna Wathoo, Kenna Shaw, Kenneth Hess, Russell Broaddus, Aung Naing, David Hong, Apostolia M. Tsimberidou, Daniel Karp, James Yao, Funda Meric-Bernstam, and Siqing Fu
33796-33806

Abstract  |  PDF  |  Full Text  |  How to cite

Pharmacologic targeting ERK1/2 attenuates the development and progression of hyperuricemic nephropathy in rats	Pharmacologic targeting ERK1/2 attenuates the development and progression of hyperuricemic nephropathy in rats
https://doi.org/10.18632/oncotarget.16995 Na Liu, Liuqing Xu, Yingfeng Shi, Lu Fang, Hongwei Gu, Hongrui Wang, Xiaoqiang Ding, and Shougang Zhuang
33807-33826

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Variable step size methods for solving simultaneous algebraic reconstruction technique SARTtype CBCT reconstructions	Variable step size methods for solving simultaneous algebraic reconstruction technique SARTtype CBCT reconstructions
https://doi.org/10.18632/oncotarget.17385 Heui Chang Lee, Bongyong Song, Jin Sung Kim, James J. Jung, H.Harold Li, Sasa Mutic, and Justin C. Park
33827-33835

Abstract  |  PDF  |  Full Text  |  How to cite

Clinical Research Papers

Dynamic contrastenhanced magnetic resonance imaging for pretreatment prediction of early chemoradiotherapy response in larynx and hypopharynx carcinoma	Dynamic contrastenhanced magnetic resonance imaging for pretreatment prediction of early chemoradiotherapy response in larynx and hypopharynx carcinoma
https://doi.org/10.18632/oncotarget.12952 Wei Guo, Dehong Luo, Xinyi Chen, Meng Lin, Lin Li, Yanfeng Zhao, Liang Yang, Lei Hu, Xinming Zhao, and Chunwu Zhou
33836-33843

Abstract  |  PDF  |  Full Text  |  How to cite

Prognostic impact of fibroblast growth factor receptor 2 gene amplification in patients receiving fluoropyrimidine and platinum chemotherapy for metastatic and locally advanced unresectable gastric cancers	Prognostic impact of fibroblast growth factor receptor 2 gene amplification in patients receiving fluoropyrimidine and platinum chemotherapy for metastatic and locally advanced unresectable gastric cancers
https://doi.org/10.18632/oncotarget.12953 Seyoung Seo, Seong Joon Park, Min-Hee Ryu, Sook Ryun Park, Baek-Yeol Ryoo, Young Soo Park, Young-Soon Na, Chae-Won Lee, Ju-Kyung Lee, and Yoon-Koo Kang
33844-33854

Abstract  |  PDF  |  Full Text  |  How to cite

Dosimetric factors and Lyman normaltissue complication modelling analysis for predicting radiationinduced lung injury in postoperative breast cancer radiotherapy: a prospective study	Dosimetric factors and Lyman normaltissue complication modelling analysis for predicting radiationinduced lung injury in postoperative breast cancer radiotherapy: a prospective study
https://doi.org/10.18632/oncotarget.12979 Zhi-Rui Zhou, Qing Han, Shi-Xiong Liang, Xiao-Dong He, Nu-Yun Cao, and Ying-Jie Zi
33855-33863

Abstract  |  PDF  |  Full Text  |  How to cite

Repetitive transcranial magnetic stimulation improves cognitive function of Alzheimer’s disease patients	Repetitive transcranial magnetic stimulation improves cognitive function of Alzheimer’s disease patients
https://doi.org/10.18632/oncotarget.13060 Junwu Zhao, Zhenguang Li, Yannan Cong, Jinbiao Zhang, Ming Tan, Haixia Zhang, Na Geng, Mengfan Li, Wenwen Yu, and Peiyan Shan
33864-33871

Abstract  |  PDF  |  Full Text  |  How to cite

Minimally invasive distal pancreatectomy for PNETs: laparoscopic or robotic approach	Minimally invasive distal pancreatectomy for PNETs: laparoscopic or robotic approach
https://doi.org/10.18632/oncotarget.17513 Jiaqiang Zhang, Jiabin Jin, Shi Chen, Jiangning Gu, Yi Zhu, Kai Qin, Qian Zhan, Dongfeng Cheng, Hao Chen, Xiaxing Deng, Baiyong Shen, and Chenghong Peng
33872-33883

Abstract  |  PDF  |  Full Text  |  How to cite

Reviews

Prognostic value of 18FFDGPET/CT in patients with nasopharyngeal carcinoma: a systematic review and metaanalysis	Prognostic value of 18FFDGPET/CT in patients with nasopharyngeal carcinoma: a systematic review and metaanalysis
https://doi.org/10.18632/oncotarget.13934 Jie Lin, Guozhu Xie, Guixiang Liao, Baiyao Wang, Miaohong Yan, Hui Li, and Yawei Yuan
33884-33896

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Immunotherapeutic approaches for hepatocellular carcinoma	Immunotherapeutic approaches for hepatocellular carcinoma
https://doi.org/10.18632/oncotarget.15406 Vito Longo, Antonio Gnoni, Andrea Casadei Gardini, Salvatore Pisconti, Antonella Licchetta, Mario Scartozzi, Riccardo Memeo, Vincenzo Ostilio Palmieri, Giuseppe Aprile, Daniele Santini, Patrizia Nardulli, Nicola Silvestris, and Oronzo Brunetti
33897-33910

Abstract  |  PDF  |  Full Text  |  How to cite

Treatment of hepatocellular carcinoma with portal vein tumor thrombus: advances and challenges	Treatment of hepatocellular carcinoma with portal vein tumor thrombus: advances and challenges
https://doi.org/10.18632/oncotarget.15411 Jin-Fang Jiang, Yong-Cong Lao, Bao-Hong Yuan, Jun Yin, Xin Liu, Long Chen, and Jian-Hong Zhong
33911-33921

Abstract  |  PDF  |  Full Text  |  How to cite

Prognostic value of EGFR and KRAS in circulating tumor DNA in patients with advanced nonsmall cell lung cancer: a systematic review and metaanalysis	Prognostic value of EGFR and KRAS in circulating tumor DNA in patients with advanced nonsmall cell lung cancer: a systematic review and metaanalysis
https://doi.org/10.18632/oncotarget.15412 Gaowei Fan, Kuo Zhang, Jiansheng Ding, and Jinming Li
33922-33932

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

T2 mycotoxin: toxicological effects and decontamination strategies	T2 mycotoxin: toxicological effects and decontamination strategies
https://doi.org/10.18632/oncotarget.15422 Manish Adhikari, Bhawana Negi, Neha Kaushik, Anupriya Adhikari, Abdulaziz A. Al-Khedhairy, Nagendra Kumar Kaushik, and Eun Ha Choi
33933-33952

Abstract  |  PDF  |  Full Text  |  How to cite

Genetic association between PSA158G/A polymorphism and the susceptibility of benign prostatic hyperplasia: a metaanalysis	Genetic association between PSA158G/A polymorphism and the susceptibility of benign prostatic hyperplasia: a metaanalysis
https://doi.org/10.18632/oncotarget.15424 Xin-Jun Su, Xian-Tao Zeng, Cheng Fang, Tong-Zu Liu, and Xing-Huan Wang
33953-33960

Abstract  |  PDF  |  Full Text  |  How to cite

Clinical efficacy of icotinib in lung cancer patients with different EGFR mutation status: a metaanalysis	Clinical efficacy of icotinib in lung cancer patients with different EGFR mutation status: a metaanalysis
https://doi.org/10.18632/oncotarget.15475 Jian Qu, Ya-Nan Wang, Ping Xu, Da-Xiong Xiang, Rui Yang, Wei Wei, and Qiang Qu
33961-33971

Abstract  |  PDF  |  Full Text  |  How to cite

The regulation of βcatenin activity and function in cancer: therapeutic opportunities	The regulation of βcatenin activity and function in cancer: therapeutic opportunities
https://doi.org/10.18632/oncotarget.15687 Shuang Shang, Fang Hua, and Zhuo-Wei Hu
33972-33989

Abstract  |  PDF  |  Full Text  |  How to cite

Association of body mass index with bladder cancer risk: a doseresponse metaanalysis of prospective cohort studies	Association of body mass index with bladder cancer risk: a doseresponse metaanalysis of prospective cohort studies
https://doi.org/10.18632/oncotarget.16722 Limin Zhao, Xiaoqin Tian, Xueyan Duan, Yongxiu Ye, Min Sun, and Junfang Huang
33990-34000

Abstract  |  PDF  |  Full Text  |  How to cite

Systematic review and metaanalysis of the efficacy and safety of novel monoclonal antibodies for treatment of relapsed/refractory multiple myeloma	Systematic review and metaanalysis of the efficacy and safety of novel monoclonal antibodies for treatment of relapsed/refractory multiple myeloma
https://doi.org/10.18632/oncotarget.16987 Tiantian Zhang, Sen Wang, Tengfei Lin, Jingmei Xie, Lina Zhao, Zhuoru Liang, Yangqiu Li, and Jie Jiang
34001-34017

Abstract  |  PDF  |  Full Text  |  How to cite

Corrections

Correction: miR4245p promotes proliferation of gastric cancer by targeting Smad3 through TGFβ signaling pathway	Correction: miR4245p promotes proliferation of gastric cancer by targeting Smad3 through TGFβ signaling pathway
https://doi.org/10.18632/oncotarget.17876 Song Wei, Qing Li, Zheng Li, Linjun Wang, Lei Zhang, and Zekuan Xu
34018-34018

Correction  |  PDF  |  How to cite

Retraction

Retraction: Androgen receptor CAG and GGN repeat length variation contributes more to the tumorigenesis of osteosarcoma	Retraction: Androgen receptor CAG and GGN repeat length variation contributes more to the tumorigenesis of osteosarcoma
https://doi.org/10.18632/oncotarget.17877 Yongxiang Shi, Weishan Chen, Qinghuai Li, and Zhaoming Ye
34019-34019

Retraction  |  PDF  |  How to cite

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