Vol 8, No 20

A polymorphism at IGF1 locus is associated with anemia

BRCA1 controls the cell division axis and governs ploidy and phenotype in human mammary cells

Increased B cell activation is present in JAK2V617F-mutated, CALR-mutated and triple-negative essential thrombocythemia

New transcriptional-based insights into the pathogenesis of desmoplastic small round cell tumors (DSRCTs)

Galectin-1 expression imprints a neurovascular phenotype in proliferative retinopathies and delineates responses to anti-VEGF

Midkine promotes hepatocellular carcinoma metastasis by elevating anoikis resistance of circulating tumor cells

Immunotherapeutic target expression on breast tumors can be amplified by hormone receptor antagonism: a novel strategy for enhancing efficacy of targeted immunotherapy

High-dose ascorbate and arsenic trioxide selectively kill acute myeloid leukemia and acute promyelocytic leukemia blasts in vitro

miR-29a regulated ER-positive breast cancer cell growth and invasion and is involved in the insulin signaling pathway

NADPH accumulation is responsible for apoptosis in breast cancer cells induced by fatty acid synthase inhibition

Deguelin inhibits non-small cell lung cancer via down-regulating Hexokinases II-mediated glycolysis

Histopathologic tumor invasion of superior mesenteric vein/ portal vein is a poor prognostic indicator in patients with pancreatic ductal adenocarcinoma: results from a systematic review and meta-analysis

Assessment of the interlaboratory variability and robustness of JAK2^V617F mutation assays: A study involving a consortium of 19 Italian laboratories

Diversity of the association of serum levels and genetic variants of MHC class I polypeptide-related chain A with liver fibrosis in chronic hepatitis C

Clinical features and treatment outcome of non-small cell lung cancer (NSCLC) patients with uncommon or complex epidermal growth factor receptor (EGFR) mutations

UBE2T knockdown inhibits gastric cancer progression

EGFR inhibition attenuates diabetic nephropathy through decreasing ROS and endoplasmic reticulum stress

Epidermal growth factor receptor variant III in head and neck squamous cell carcinoma is not relevant for targeted therapy and irradiation

USP22 drives colorectal cancer invasion and metastasis via epithelial-mesenchymal transition by activating AP4

Long intergenic noncoding RNA 00673 promotes non-small-cell lung cancer metastasis by binding with EZH2 and causing epigenetic silencing of HOXA5

High mobility group box 1 antagonist limits metastatic seeding in the lungs via reduction of cell–cell adhesion

Tumor-derived IL-18 induces PD-1 expression on immunosuppressive NK cells in triple-negative breast cancer

Prognostic roles of Notch receptor mRNA expression in human ovarian cancer

Theranostic imaging of liver cancer using targeted optical/MRI dual-modal probes

Uncoupling genotoxic stress responses from circadian control increases susceptibility to mammary carcinogenesis

microRNA-200c/141 upregulates SerpinB2 to promote breast cancer cell metastasis and reduce patient survival

MMP-11 promoted the oral cancer migration and FAK/Src activation

Metformin inhibits ALK1-mediated angiogenesis via activation of AMPK

Coroglaucigenin enhances the radiosensitivity of human lung cancer cells through Nrf2/ROS pathway

Identification of DBCCR1 as a suppressor in the development of lung cancer that is associated with increased DNA methyltransferase 1

KPNB1-mediated nuclear import is required for motility and inflammatory transcription factor activity in cervical cancer cells

Hormone receptor expression profiles differ between primary and recurrent high-grade serous ovarian cancers

A(H1N1)pdm09 influenza infection: vaccine inefficiency

ROR1 expression as a biomarker for predicting prognosis in patients with colorectal cancer

Hypoxia activates placental growth factor expression in lymphatic endothelial cells

Combinatorial treatment with polyI:C and anti-IL6 enhances apoptosis and suppresses metastasis of lung cancer cells

LncRNA HOTAIR acts as competing endogenous RNA to control the expression of Notch3 via sponging miR-613 in pancreatic cancer

A phase 2 study of vorinostat in locally advanced, recurrent, or metastatic adenoid cystic carcinoma

Characteristics of prostate cancer detection rate (PCDR) in Chinese Han population under different prostate biopsy methods

Huaier aqueous extract protects against dextran sulfate sodium-induced experimental colitis in mice by inhibiting NLRP3 inflammasome activation

Glucose availability controls ATF4-mediated MITF suppression to drive melanoma cell growth

Penfluridol suppresses glioblastoma tumor growth by Akt-mediated inhibition of GLI1

Ccl5 establishes an autocrine high-grade glioma growth regulatory circuit critical for mesenchymal glioblastoma survival

Novel RNA biomarkers of prostate cancer revealed by RNA-seq analysis of formalin-fixed samples obtained from Russian patients

The relationship between members of the canonical NF-κB pathway, components of tumour microenvironment and survival in patients with invasive ductal breast cancer

Patients with uterine leiomyoma exhibit a high incidence but low mortality rate for breast cancer

Enhanced anti-tumor therapeutic efficacy of DNA vaccine by fusing the E7 gene to BAFF in treating human papillomavirus-associated cancer

Metallothionein 1M suppresses tumorigenesis in hepatocellular carcinoma

iNOS-derived nitric oxide promotes glycolysis by inducing pyruvate kinase M2 nuclear translocation in ovarian cancer

MiR-145 negatively regulates Warburg effect by silencing KLF4 and PTBP1 in bladder cancer cells

Classification of pediatric acute myeloid leukemia based on miRNA expression profiles

NELL1, whose high expression correlates with negative outcomes, has different methylation patterns in alveolar and embryonal rhabdomyosarcoma

DNA methylation profiling identifies the HOXA11 gene as an early diagnostic and prognostic molecular marker in human lung adenocarcinoma

NID1, a new regulator of EMT required for metastasis and chemoresistance of ovarian cancer cells

Monoglyceride lipase deficiency affects hepatic cholesterol metabolism and lipid-dependent gut transit in ApoE−/− mice

Upregulation of long non-coding RNA HOXA-AS2 promotes proliferation and induces epithelial-mesenchymal transition in gallbladder carcinoma

Long noncoding RNA ROR regulates chemoresistance in docetaxel-resistant lung adenocarcinoma cells via epithelial mesenchymal transition pathway

Preferential accumulation of regulatory T cells with highly immunosuppressive characteristics in breast tumor microenvironment

Transcriptional regulation of mixed lineage kinase 3 by estrogen and its implication in ER-positive breast cancer pathogenesis

Poor efficacy response to trastuzumab therapy in advanced gastric cancer with homogeneous HER2 positive and non-intestinal type

(DEAD)-box RNA helicase 3 modulates NF-κB signal pathway by controlling the phosphorylation of PP2A-C subunit

CD200Fc reduces LPS-induced IL-1β activation in human cervical cancer cells by modulating TLR4-NF-κB and NLRP3 inflammasome pathway

The design of novel inhibitors for treating cancer by targeting CDC25B through disruption of CDC25B-CDK2/Cyclin A interaction using computational approaches

DNA plasmid vaccine carrying Chlamydia trachomatis (Ct) major outer membrane and human papillomavirus 16L2 proteins for anti-Ct infection

Magnesium isoglycyrrhizinate shows hepatoprotective effects in a cyclophosphamide-induced model of hepatic injury

Correlated high expression of FXR and Sp1 in cancer cells confers a poor prognosis for pancreatic cancer: A study based on TCGA and tissue microarray

Intensity modulated radiotherapy with fixed collimator jaws for locoregional left-sided breast cancer irradiation

Clinical significance of the correlation between PLCE 1 and PRKCA in esophageal inflammation and esophageal carcinoma

IGF1R depletion facilitates MET-amplification as mechanism of acquired resistance to erlotinib in HCC827 NSCLC cells

The p38 signaling pathway mediates quiescence of glioma stem cells by regulating epidermal growth factor receptor trafficking

USP22 maintains gastric cancer stem cell stemness and promotes gastric cancer progression by stabilizing BMI1 protein

Hypoxia-inducible factor 1a induces phenotype switch of human aortic vascular smooth muscle cell through PI3K/AKT/AEG-1 signaling

Actin cytoskeleton regulator Arp2/3 complex is required for DLL1 activating Notch1 signaling to maintain the stem cell phenotype of glioma initiating cells

Expression of EMT markers and mode of surgery are prognostic in phyllodes tumors of the breast

Clinical significance of circulating miR-25-3p as a novel diagnostic and prognostic biomarker in osteosarcoma

Imaging and targeted therapy of pancreatic ductal adenocarcinoma using the theranostic sodium iodide symporter (NIS) gene

A novel BMX variant promotes tumor cell growth and migration in lung adenocarcinoma

Sequential evaluation of CALR mutant burden in patients with myeloproliferative neoplasms

C3orf21 ablation promotes the proliferation of lung adenocarcinoma, and its mutation at the rs2131877 locus may serve as a susceptibility marker

SOCS3 treatment prevents the development of alopecia areata by inhibiting CD8+ T cell-mediated autoimmune destruction

Fbxw7 haploinsufficiency loses its protection against DNA damage and accelerates MNU-induced gastric carcinogenesis

The dominant role of proofreading exonuclease activity of replicative polymerase ε in cellular tolerance to cytarabine (Ara-C)

Microrna-217 modulates human skin fibroblast senescence by directly targeting DNA methyltransferase 1

Clinical and prognostic significance of aberrant T-cell marker expression in 225 cases of de novo diffuse large B-cell lymphoma and 276 cases of other B-cell lymphomas

IL-35 induces N2 phenotype of neutrophils to promote tumor growth

Caspase 12 degrades IκBα protein and enhances MMP-9 expression in human nasopharyngeal carcinoma cell invasion

Identification of STXBP2 as a novel susceptibility locus for myocardial infarction in Japanese individuals by an exome-wide association study

Genetic variation of long non-coding RNA TINCR contribute to the susceptibility and progression of colorectal cancer

Loss of Tpm4.1 leads to disruption of cell-cell adhesions and invasive behavior in breast epithelial cells via increased Rac1 signaling

Transforming growth factor β1 promotes invasion of human JEG-3 trophoblast cells via TGF-β/Smad3 signaling pathway

Utilizing combinatorial engineering to develop Tie2 targeting antagonistic angiopoetin-2 ligands as candidates for anti-angiogenesis therapy

Overexpression of NOX4 predicts poor prognosis and promotes tumor progression in human colorectal cancer

Effect of Salmonella enterica serovar Typhimurium VNP20009 and VNP20009 with restored chemotaxis on 4T1 mouse mammary carcinoma progression

Correlation of genomic alterations assessed by next-generation sequencing (NGS) of tumor tissue DNA and circulating tumor DNA (ctDNA) in metastatic renal cell carcinoma (mRCC): potential clinical implications

MiR-199a-3p enhances cisplatin sensitivity of cholangiocarcinoma cells by inhibiting mTOR signaling pathway and expression of MDR1

Non-invasive prediction of the tumor growth rate using advanced diffusion models in head and neck squamous cell carcinoma patients

FOXD3 regulates anaplastic thyroid cancer progression

Chronic grouped social restriction triggers long-lasting immune system adaptations

Skeletal muscle measures and physical function in older adults with cancer: sarcopenia or myopenia?

TAK1 inhibitor 5Z-7-oxozeaenol sensitizes cervical cancer to doxorubicin-induced apoptosis

Risk factors for the recurrence of an intracranial saccular aneurysm following endovascular treatment

Growth-suppressive activity of raloxifene on liver cancer cells by targeting IL-6/GP130 signaling

AKR1B10 promotes breast cancer cell migration and invasion via activation of ERK signaling

Ulk1 over-expression in human gastric cancer is correlated with patients' T classification and cancer relapse

Prognostic role of the long non-coding RNA, SPRY4 Intronic Transcript 1, in patients with cancer: a meta-analysis

Antagonistic effects of selenium on lead-induced autophagy by influencing mitochondrial dynamics in the spleen of chickens

The role of metabolic tumor volume (MTV) measured by [18F] FDG PET/CT in predicting EGFR gene mutation status in non-small cell lung cancer

Functional analysis implicating the SNP rs61552325 in ERBB2 as an effector for androgen-insensitive prostate cancer cell invasion

Melatonin exerts anti-oral cancer effect via suppressing LSD1 in patient-derived tumor xenograft models

Combination analysis of NOS3, ABCB1 and IL23R polymorphisms with alcohol-induced osteonecrosis of the femoral head risk in Chinese males

SEL120-34A is a novel CDK8 inhibitor active in AML cells with high levels of serine phosphorylation of STAT1 and STAT5 transactivation domains

Antiangiogenesis and gene aberration-related therapy may improve overall survival in patients with concurrent KRAS and TP53 hotspot mutant cancer

Pharmacologic targeting ERK1/2 attenuates the development and progression of hyperuricemic nephropathy in rats

Variable step size methods for solving simultaneous algebraic reconstruction technique (SART)-type CBCT reconstructions

Prognostic impact of fibroblast growth factor receptor 2 gene amplification in patients receiving fluoropyrimidine and platinum chemotherapy for metastatic and locally advanced unresectable gastric cancers

Dosimetric factors and Lyman normal-tissue complication modelling analysis for predicting radiation-induced lung injury in postoperative breast cancer radiotherapy: a prospective study

Repetitive transcranial magnetic stimulation improves cognitive function of Alzheimer’s disease patients

Minimally invasive distal pancreatectomy for PNETs: laparoscopic or robotic approach?

Immunotherapeutic approaches for hepatocellular carcinoma

Treatment of hepatocellular carcinoma with portal vein tumor thrombus: advances and challenges

Prognostic value of EGFR and KRAS in circulating tumor DNA in patients with advanced non-small cell lung cancer: a systematic review and meta-analysis

T-2 mycotoxin: toxicological effects and decontamination strategies

Genetic association between PSA-158G/A polymorphism and the susceptibility of benign prostatic hyperplasia: a meta-analysis

Clinical efficacy of icotinib in lung cancer patients with different EGFR mutation status: a meta-analysis

The regulation of β-catenin activity and function in cancer: therapeutic opportunities

Association of body mass index with bladder cancer risk: a dose-response meta-analysis of prospective cohort studies

Systematic review and meta-analysis of the efficacy and safety of novel monoclonal antibodies for treatment of relapsed/refractory multiple myeloma