Vol 8, No 4

AGEs and neurodegeneration: the Nrf2/glyoxalase-1 interaction

Large-scale genomic deletions mediated by CRISPR/Cas9 system

PRAK mediates Aβ-RAGE driven autophagy pathway

Uniquely conserved immunosuppressive viral exoribonucleases

Epigenetic regulation of general anesthesia-induced neonatal neurodegeneration

Trapping the oligomers: new promises in neurosciences

MiRNA-34 and stress response

Understanding histone deacetylation in Huntington’s disease

Regulation of RIC-3 and of nAChR expression

Glutamate transporters: The arrestin connection

Progress in CSF biomarker discovery in sCJD

VTA BDNF enhances social stress-induced compulsive cocaine bingeing

Pathophysiological role of zinc in ischemic brain injury

GDE2/GDPD5 in neuroblastoma

mTOR pathway in familial focal epilepsies

Ephrins in astrocytes: synaptic erasers on stage

Molecular rescue of Tsc1-ablated cortical tuber mice

Myelinating cells can feel disturbances in the force

Environment as therapy: neuroscience for intellectual disability and dementia

Assessing alcohol and nicotine co-consumption in mice

Hormophysa triquerta polyphenol, an elixir that deters CXCR4- and COX2-dependent dissemination destiny of treatment-resistant pancreatic cancer cells

Sp1-mediated transcriptional activation of miR-205 promotes radioresistance in esophageal squamous cell carcinoma

Early detection of rheumatoid arthritis in rats and humans with ⁹⁹mTc-3PRGD2 scintigraphy: imaging synovial neoangiogenesis

Genomic binding of PAX8-PPARG fusion protein regulates cancer-related pathways and alters the immune landscape of thyroid cancer

RHCG and TCAF1 promoter hypermethylation predicts biochemical recurrence in prostate cancer patients treated by radical prostatectomy

Decreased TCL6 expression is associated with poor prognosis in patients with clear cell renal cell carcinoma

Cucurbitacin B exerts anti-cancer activities in human multiple myeloma cells in vitro and in vivo by modulating multiple cellular pathways

Association between Retinoic acid receptor-β hypermethylation and NSCLC risk: a meta-analysis and literature review

ErbB2 inhibition by lapatinib promotes degradation of mutant p53 protein in cancer cells

Noninvasive amide proton transfer magnetic resonance imaging in evaluating the grading and cellularity of gliomas

Improved clinical outcomes of patients with ovarian carcinoma arising in endometriosis

Ablation of hepatic malignant tumors with irreversible electroporation: A systematic review and meta-analysis of outcomes

Total DNA input is a crucial determinant of the sensitivity of plasma cell-free DNA EGFR mutation detection using droplet digital PCR

Novel multiple tyrosine kinase inhibitor ponatinib inhibits bFGF-activated signaling in neuroblastoma cells and suppresses neuroblastoma growth in vivo

A novel method for RNA extraction from FFPE samples reveals significant differences in biomarker expression between orthotopic and subcutaneous pancreatic cancer patient-derived xenografts

Extracellular ATP induces apoptosis through P2X7R activation in acute myeloid leukemia cells but not in normal hematopoietic stem cells

Gankyrin promotes epithelial-mesenchymal transition and metastasis in NSCLC through forming a closed circle with IL-6/ STAT3 and TGF-β/SMAD3 signaling pathway

Minimal residual disease after transplantation or lenalidomide-based consolidation in myeloma patients: a prospective analysis

Lycium barbarum polysaccharides inhibit proliferation and migration of bladder cancer cell lines BIU87 by suppressing Pi3K/AKT pathway

Myostatin-deficiency in mice increases global gene expression at the Dlk1-Dio3 locus in the skeletal muscle

Low-dose bortezomib increases the expression of NKG2D and DNAM-1 ligands and enhances induced NK and γδ T cell-mediated lysis in multiple myeloma

Serine protease inhibitor kazal-type 6 inhibits tumorigenesis of human hepatocellular carcinoma cells via its extracellular action

STC2 promotes head and neck squamous cell carcinoma metastasis through modulating the PI3K/AKT/Snail signaling

RICTOR amplification identifies a subgroup in small cell lung cancer and predicts response to drugs targeting mTOR

Clinicopathological and prognostic significance of COX-2 immunohistochemical expression in breast cancer: a meta-analysis

Common profiles of Notch signaling differentiate disease-free survival in luminal type A and triple negative breast cancer

Sublobar resection is associated with improved outcomes over radiotherapy in the management of high-risk elderly patients with Stage I non-small cell lung cancer: a systematic review and meta-analysis

A mononucleotide repeat in PRRT2 is an important, frequent target of mismatch repair deficiency in cancer

Preclinical evaluation of the PARP inhibitor BMN-673 for the treatment of ovarian clear cell cancer

MBD3 inhibits formation of liver cancer stem cells

Methicillin-resistant Staphylococcus aureus isolates in a hospital of Shanghai

Genome-wide methylation sequencing of paired primary and metastatic cell lines identifies common DNA methylation changes and a role for EBF3 as a candidate epigenetic driver of melanoma metastasis

Idelalisib induces PUMA-dependent apoptosis in colon cancer cells

PRKAR2B plays an oncogenic role in the castration-resistant prostate cancer

Tonsillar CD56^brightNKG2A⁺ NK cells restrict primary Epstein-Barr virus infection in B cells via IFN-γ

Dysregulated miR34a/diacylglycerol kinase ζ interaction enhances T-cell activation in acquired aplastic anemia

PTEN mediates the cross talk between breast and glial cells in brain metastases leading to rapid disease progression

Down-regulation of CITED2 attenuates breast tumor growth, vessel formation and TGF-β-induced expression of VEGFA

Combination treatment of prostate cancer with FGF receptor and AKT kinase inhibitors

The tumor-associated YB-1 protein: new player in the circadian control of cell proliferation

Similar outcomes between adenoid cystic carcinoma of the breast and invasive ductal carcinoma: a population-based study from the SEER 18 database

A common CD55 rs2564978 variant is associated with the susceptibility of non-small cell lung cancer

A comparison of the clinicopathological features and prognoses of the classical and the tall cell variant of papillary thyroid cancer: a meta-analysis

Protective effects of resveratrol against mancozeb induced apoptosis damage in mouse oocytes

MARCKS protein overexpression in inflammatory breast cancer

Precise integrin-targeting near-infrared imaging-guided surgical method increases surgical qualification of peritoneal carcinomatosis from gastric cancer in mice

Adenosine 5′-monophosphate blocks acetaminophen toxicity by increasing ubiquitination-mediated ASK1 degradation

Abnormal brain functional connectivity leads to impaired mood and cognition in hyperthyroidism: a resting-state functional MRI study

BRAF-activated lncRNA predicts gastrointestinal cancer patient prognosis: a meta-analysis

mir-218-2 promotes glioblastomas growth, invasion and drug resistance by targeting CDC27

Histone deacetylases 1 and 2 cooperate in regulating BRCA1, CHK1, and RAD51 expression in acute myeloid leukemia cells

Diagnostic and prognostic value of circulating tumor DNA in gastric cancer: a meta-analysis

In vitro and in vivo anti-leukemic activity of the peptidase-potentiated alkylator melflufen in acute myeloid leukemia

Filamin C promotes lymphatic invasion and lymphatic metastasis and increases cell motility by regulating Rho GTPase in esophageal squamous cell carcinoma

Radiolabeled novel mAb 4G1 for immunoSPECT imaging of EGFRvIII expression in preclinical glioblastoma xenografts

Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism

A novel assay to detect calreticulin mutations in myeloproliferative neoplasms

Cell-free methylation markers with diagnostic and prognostic potential in hepatocellular carcinoma

Autophagy inhibition enhances photocytotoxicity of Photosan-II in human colorectal cancer cells

Resistance to glucose starvation as metabolic trait of platinum-resistant human epithelial ovarian cancer cells

Use of non-selective β-blockers is associated with decreased tumor proliferative indices in early stage breast cancer

Activation of ATR-Chk1 pathway facilitates EBV-mediated transformation of primary tonsillar B-cells

Variants in microRNA genes in familial papillary thyroid carcinoma

Recurrent genetic defects on chromosome 5q in myeloid neoplasms

TIMP-1 and CD82, a promising combined evaluation marker for PDAC

A six-microRNA panel in plasma was identified as a potential biomarker for lung adenocarcinoma diagnosis

HER3 and LINC00052 interplay promotes tumor growth in breast cancer

Multiple drug resistance-associated protein (MRP4) exports prostaglandin E₂ (PGE₂) and contributes to metastasis in basal/triple negative breast cancer

High expression of the long non-coding RNA HEIRCC promotes Renal Cell Carcinoma metastasis by inducing epithelial-mesenchymal transition

Targeted delivery of nano-PTX to the brain tumor-associated macrophages

Whole-exome sequencing identified mutational profiles of high-grade colon adenomas

The long non-coding RNA GAS5 differentially regulates cell cycle arrest and apoptosis through activation of BRCA1 and p53 in human neuroblastoma

Subcellular localization of FOXO3a as a potential biomarker of response to combined treatment with inhibitors of PI3K and autophagy in PIK3CA-mutant cancer cells

Circulating thyroid stimulating hormone receptor messenger RNA and differentiated thyroid cancer: A diagnostic meta-analysis

Effects of alcohol consumption, ALDH2 rs671 polymorphism, and Helicobacter pylori infection on the gastric cancer risk in a Korean population

Interactive role of diabetes mellitus and female sex in the risk of cholangiocarcinoma: A population-based nested case–control study

Robust transcriptional tumor signatures applicable to both formalin-fixed paraffin-embedded and fresh-frozen samples

Interleukin-17A promotes tongue squamous cell carcinoma metastasis through activating miR-23b/versican pathway

Integrin α6 promotes esophageal cancer metastasis and is targeted by miR-92b

Cordycepin induces autophagy-mediated c-FLIP_L degradation and leads to apoptosis in human non-small cell lung cancer cells

Role of VHL, HIF1A and SDH on the expression of miR-210: Implications for tumoral pseudo-hypoxic fate

Positive feedback loop of IL-1β/Akt/RARα/Akt signaling mediates oncogenic property of RARα in gastric carcinoma

The GSK461364 PLK1 inhibitor exhibits strong antitumoral activity in preclinical neuroblastoma models

CD147: a small molecule transporter ancillary protein at the crossroad of multiple hallmarks of cancer and metabolic reprogramming

Induction chemotherapy for the treatment of non-endemic locally advanced nasopharyngeal carcinoma

Comprehensive tissue-specific gene set enrichment analysis and transcription factor analysis of breast cancer by integrating 14 gene expression datasets

EglN2 contributes to triple negative breast tumorigenesis by functioning as a substrate for the FBW7 tumor suppressor

A novel nonsense mutation in androgen receptor confers resistance to CYP17 inhibitor treatment in prostate cancer

Pan-organ transcriptome variation across 21 cancer types

Proteins that interact with calgranulin B in the human colon cancer cell line HCT-116

The prognostic value of long noncoding RNA HOTTIP on clinical outcomes in breast cancer

Quantitative assessment of the diagnostic role of FHIT promoter methylation in non-small cell lung cancer

N-glycosylation converts non-glycoproteins into mannose receptor ligands and reveals antigen-specific T cell responses in vivo

Vitamin D deficiency is associated with a worse prognosis in metastatic melanoma

Expression of pannexin 1 and 2 in cortical lesions from intractable epilepsy patients with focal cortical dysplasia

Assessing the clinical value of microRNAs in formalin-fixed paraffin-embedded liposarcoma tissues: Overexpressed miR-155 is an indicator of poor prognosis

Therapeutic potential of the metabolic modulator phenformin in targeting the stem cell compartment in melanoma

A retrospective study of NENs and miR-224 promotes apoptosis of BON-1 cells by targeting PCSK9 inhibition

c-Jun-N-terminal phosphorylation regulates DNMT1 expression and genome wide methylation in gliomas

Clinical and biological significance of miR-23b and miR-193a in human hepatocellular carcinoma

High expression of miR-181c as a predictive marker of recurrence in stage II colorectal cancer

Desuccinylation of pyruvate kinase M2 by SIRT5 contributes to antioxidant response and tumor growth

Circulating miR-1 as a potential biomarker of doxorubicin-induced cardiotoxicity in breast cancer patients

Comparative effectiveness of combined therapy inhibiting EGFR and VEGF pathways in patients with advanced non-small-cell lung cancer: a meta-analysis of 16 phase II/III randomized trials

Mucins and associated O-glycans based immunoprofile for stratification of colorectal polyps: clinical implication for improved colon surveillance

Survival prediction in patients undergoing radionuclide therapy based on intratumoral somatostatin-receptor heterogeneity

Solid predominant histologic subtype and early recurrence predict poor postrecurrence survival in patients with stage I lung adenocarcinoma

Advances in sarcoma diagnostics and treatment

Stem-like plasticity and heterogeneity of circulating tumor cells: current status and prospect challenges in liver cancer

Friend or foe: the dichotomous impact of T cells on neuro-de/re-generation during aging

Implications of immune dysfunction on endometriosis associated infertility

A meta-analysis on the effect of operation modes on the recurrence of papillary thyroid microcarcinoma

Targeting immune checkpoints in malignant glioma

The concept of immune surveillance against tumors: The first theories

Recent development of ATP-competitive small molecule phosphatidylinostitol-3-kinase inhibitors as anticancer agents

Bruton tyrosine kinase inhibitor ONO/GS-4059: from bench to bedside