Vol 8, No 21

A neurorestorative approach to Parkinson’s disease

M channels and stress response

ATXN2 a culprit with multiple facets

HDAC/IKK inhibition therapies in solid tumors

Examining the association between anthropometric parameters and telomere length and mortality risk

Honokiol, an activator of Sirtuin-3 (SIRT3) preserves mitochondria and protects the heart from doxorubicin-induced cardiomyopathy in mice

Combined experience of six independent laboratories attempting to create an Ewing sarcoma mouse model

Upregulation of the long non-coding RNA PVT1 promotes esophageal squamous cell carcinoma progression by acting as a molecular sponge of miR-203 and LASP1

CRISPR Cas9-guided chromatin immunoprecipitation identifies miR483 as an epigenetic modulator of IGF2 imprinting in tumors

Involvement of heparanase in the pathogenesis of acute kidney injury: nephroprotective effect of PG545

Employing an orthotopic model to study the role of epithelial-mesenchymal transition in bladder cancer metastasis

Isoliquiritigenin suppresses human T Lymphocyte activation via covalently binding cysteine 46 of IκB kinase

Identification of skin-related lncRNAs as potential biomarkers that are involved in Wnt pathways in keloids

Embryonic signature distinguishes pediatric and adult rhabdoid tumors from other SMARCB1-deficient cancers

Foxo3a-dependent Bim transcription protects mice from a high fat diet via inhibition of activation of the NLRP3 inflammasome by facilitating autophagy flux in Kupffer cells

Identification and characterization of RASSF1C piRNA target genes in lung cancer cells

Detection of COPB2 as a KRAS synthetic lethal partner through integration of functional genomics screens

Epha3 acts as proangiogenic factor in multiple myeloma

Robust in-silico identification of cancer cell lines based on next generation sequencing

Association between hOGG1 polymorphism rs1052133 and gastric cancer

iTRAQ-based quantitative proteomic analysis of Yamanaka factors reprogrammed breast cancer cells

Meta-analysis of oxaliplatin-based versus fluorouracil-based neoadjuvant chemoradiotherapy and adjuvant chemotherapy for locally advanced rectal cancer

Downregulation of phosphorylated MKK4 is associated with a poor prognosis in colorectal cancer patients

Notch3 overexpression enhances progression and chemoresistance of urothelial carcinoma

The long non-coding RNA NONHSAG026900 predicts prognosis as a favorable biomarker in patients with diffuse large B-cell lymphoma

High TGF-β1 expression predicts poor disease prognosis in hepatocellular carcinoma patients

Gene- gene interaction between PPARG and CYP1A1 gene on coronary artery disease in the Chinese Han population

Curcumin blocks autophagy and activates apoptosis of malignant mesothelioma cell lines and increases the survival of mice intraperitoneally transplanted with a malignant mesothelioma cell line

Relationship of p73 gene polymorphism and additional gene-smoking and gene-obesity interaction with non-small cell lung cancer risk

Long noncoding RNA PCAT-14 induces proliferation and invasion by hepatocellular carcinoma cells by inducing methylation of miR-372

Identification of long non-coding RNAs that stimulate cell survival in bladder cancer

Thymoquinone exerts potent growth-suppressive activity on leukemia through DNA hypermethylation reversal in leukemia cells

A six-microRNA signature in plasma was identified as a potential biomarker in diagnosis of esophageal squamous cell carcinoma

BALB/c mice immunized with a combination of virus-like particles incorporating Kaposi sarcoma-associated herpesvirus (KSHV) envelope glycoproteins gpK8.1, gB, and gH/gL induced comparable serum neutralizing antibody activity to UV-inactivated KSHV

18F-deoxyglucose positron emission tomography/computed tomography to predict local failure in esophageal squamous cell carcinoma

Human papillomavirus infection as a prognostic marker for lung adenocarcinoma: a systematic review and meta-analysis

NDV-D90 suppresses growth of gastric cancer and cancer-related vascularization

Citrinin exposure affects oocyte maturation and embryo development by inducing oxidative stress-mediated apoptosis

Transcriptional landscape of human cancers

Targeting mantle cell lymphoma metabolism and survival through simultaneous blockade of mTOR and nuclear transporter exportin-1

Reprogramming induced by isoliquiritigenin diminishes melanoma cachexia through mTORC2-AKT-GSK3β signaling

Saline is a more appropriate solution for microvesicles for flow cytometric analyses

Discovery and characterization of small molecule Rac1 inhibitors

Whole-genome expression analyses of type 2 diabetes in human skin reveal altered immune function and burden of infection

Dietary score and the risk of oral cancer: a case-control study in southeast China

Usefulness of the MRP2 promoter to overcome the chemoresistance of gastrointestinal and liver tumors by enhancing the expression of the drug transporter OATP1B1

A functional variant at the miRNA binding site in HMGB1 gene is associated with risk of oral squamous cell carcinoma

Use of acetaminophen and risk of endometrial cancer: evidence from observational studies

DNA methylation of METTL7A gene body regulates its transcriptional level in thyroid cancer

Changes in T-cell subpopulations and cytokine network during early period of ibrutinib therapy in chronic lymphocytic leukemia patients: the significant decrease in T regulatory cells number

Subcloning and characterization of highly metastatic cells derived from human esophageal squamous cell carcinoma KYSE150 cells by in vivo selection

MicroRNA-100 suppresses human osteosarcoma cell proliferation and chemo-resistance via ZNRF2

Identification of a novel functional JAK1 S646P mutation in acute lymphoblastic leukemia

MiR-590-3p suppresses epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma by inhibiting SIP1 expression

In vivo evaluation of the effects of simultaneous inhibition of GLUT-1 and HIF-1α by antisense oligodeoxynucleotides on the radiosensitivity of laryngeal carcinoma using micro ¹⁸F-FDG PET/CT

Digitalis use and risk of gastrointestinal cancers: A nationwide population-based cohort study

The SCLtTAxBCR-ABL transgenic mouse model closely reflects the differential effects of dasatinib on normal and malignant hematopoiesis in chronic phase-CML patients

GATA3 and TRPS1 are distinct biomarkers and prognostic factors in breast cancer: database mining for GATA family members in malignancies

Factors affecting the loss of MED12-mutated leiomyoma cells during in vitro growth

Cysteinyl leukotriene receptor 1 facilitates tumorigenesis in a mouse model of colitis-associated colon cancer

Development of new prognostic model based on pretreatment βLRI and LLRI for stage IE/IIE upper aerodigestive tract ENKTL, nasal type

Clinical framework for next generation sequencing based analysis of treatment predictive mutations and multiplexed gene fusion detection in non-small cell lung cancer

Risk of osteoporosis and pathologic fractures in cancer patients who underwent hematopoietic stem cell transplantation: a nationwide retrospective cohort study

Molecular and serologic markers of HPV 16 infection are associated with local recurrence in patients with oral cavity squamous cell carcinoma

Peripheral zone volume ratio (PZ-ratio) is relevant with biopsy results and can increase the accuracy of current diagnostic modality

Multi-omics study revealing the complexity and spatial heterogeneity of tumor-infiltrating lymphocytes in primary liver carcinoma

Validation and optimization of the Ion Torrent S5 XL sequencer and Oncomine workflow for BRCA1 and BRCA2 genetic testing

miR-509-3-5P inhibits the invasion and lymphatic metastasis by targeting PODXL and serves as a novel prognostic indicator for gastric cancer

Sensitive detection of viable circulating tumor cells using a novel conditionally telomerase-selective replicating adenovirus in non-small cell lung cancer patients

Small molecules targeting histone demethylase genes (KDMs) inhibit growth of temozolomide-resistant glioblastoma cells

Loss-of-function myostatin mutation increases insulin sensitivity and browning of white fat in Meishan pigs

Better cancer specific survival in young small cell lung cancer patients especially with AJCC stage III

Identification of common immunodominant antigens of Eimeria tenella, Eimeria acervulina and Eimeria maxima by immunoproteomic analysis

Treatment of esophageal cancer with radiation therapy: a pan-Chinese survey of radiation oncologists

Systemic inflammation response index (SIRI) predicts prognosis in hepatocellular carcinoma patients

Circular RNA alterations are involved in resistance to avian leukosis virus subgroup-J-induced tumor formation in chickens

Prospects of estrogen receptor β activation in the treatment of castration-resistant prostate cancer

Dnmt1s in donor cells is a barrier to SCNT-mediated DNA methylation reprogramming in pigs

Monocytes, endoplasmic reticulum stress and metabolomics in dogs with multiple organ dysfunction syndrome treated by continuous venovenous hemodiafiltration

Cooperative down-regulation of ribosomal protein L10 and NF-κB signaling pathway is responsible for the anti-proliferative effects by DMAPT in pancreatic cancer cells

BRCA1 haploinsufficiency cell-autonomously activates RANKL expression and generates denosumab-responsive breast cancer-initiating cells

A potential anti-tumor effect of leukotriene C₄ through the induction of 15-hydroxyprostaglandin dehydrogenase expression in colon cancer cells

Salmonella mediated the hemagglutinating virus of Japan-envelope transfer suppresses tumor growth

Gαi3 nuclear translocation causes irradiation resistance in human glioma cells

Near-infrared photoimmunotherapy: a comparison of light dosing schedules

Long term storage in liquid nitrogen leads to only minor phenotypic and gene expression changes in the mammary carcinoma model cell line BT474

NK cells and multiple myeloma-associated endothelial cells: molecular interactions and influence of IL-27

Ginkgolic acids inhibit migration in breast cancer cells by inhibition of NEMO sumoylation and NF-κB activity

Serum IL-33 level is a predictor of progression-free survival after chemotherapy

Vacquinol-1 inducible cell death in glioblastoma multiforme is counter regulated by TRPM7 activity induced by exogenous ATP

Toll-like receptor 3 as an immunotherapeutic target for KRAS mutated colorectal cancer

The clinical value, regulatory mechanisms, and gene network of the cancer-testis gene STK31 in pancreatic cancer

Serrated adenocarcinoma morphology in colorectal mucinous adenocarcinoma is associated with improved patient survival

Targeted next generation sequencing identified novel mutations in RPGRIP1 associated with both retinitis pigmentosa and Leber's congenital amaurosis in unrelated Chinese patients

Apoptosis-related microRNA-145-5p enhances the effects of pheophorbide a-based photodynamic therapy in oral cancer

Predictive blood plasma biomarkers for EGFR inhibitor-induced skin rash

Targeting autophagic cancer stem-cells to reverse chemoresistance in human triple negative breast cancer

Altered long non-coding RNAs predict worse outcome in osteosarcoma patients: evidence from a meta-analysis

Serum monocyte fraction of white blood cells is increased in patients with high Gleason score prostate cancer

Greater efficacy of intracavitary infusion of bevacizumab compared to traditional local treatments for patients with malignant cavity serous effusion

Dosimetric superiority of flattening filter free beams for single-fraction stereotactic radiosurgery in single brain metastasis

Efficacy of postoperative radiotherapy in patients with pathological stage N2 epidermal growth factor receptor wild type adenocarcinoma and squamous cell carcinoma lung cancer

Clinical validation of prospective liquid biopsy monitoring in patients with wild-type RAS metastatic colorectal cancer treated with FOLFIRI-cetuximab

Preoperative platelet to lymphocyte and neutrophil to lymphocyte ratios are independent prognostic factors for patients undergoing lung cancer radical surgery: A single institutional cohort study

A nomogram to predict the probability of axillary lymph node metastasis in female patients with breast cancer in China: A nationwide, multicenter, 10-year epidemiological study

Combination epigenetic therapy in metastatic colorectal cancer (mCRC) with subcutaneous 5-azacitidine and entinostat: a phase 2 consortium/stand Up 2 cancer study

Targeted sequencing of tonsillar and base of tongue cancer and human papillomavirus positive unknown primary of the head and neck reveals prognostic effects of mutated FGFR3

Should surgery be conducted for small nonfunctioning pancreatic neuroendocrine tumors: a systematic review

Epithelial-mesenchymal transition in prostate cancer: an overview

Fine tuning of vitamin D receptor (VDR) activity by post-transcriptional and post-translational modifications

Genetic factors associated with risk of metabolic syndrome and hepatocellular carcinoma

Sulforaphane for the chemoprevention of bladder cancer: molecular mechanism targeted approach

Impact of metformin on C-reactive protein levels in women with polycystic ovary syndrome: a meta-analysis

The importance of the genomic landscape in Waldenström’s Macroglobulinemia for targeted therapeutical interventions

Pathogenesis of ETV6/RUNX1-positive childhood acute lymphoblastic leukemia and mechanisms underlying its relapse

Metabolomics for biomarker discovery in the diagnosis, prognosis, survival and recurrence of colorectal cancer: a systematic review

Correction: Quantitative ultrasound assessment of breast tumor response to chemotherapy using a multi-parameter approach