Vol 7, No 52

Autophagy flux induced by ginsenoside-Rg3 attenuates human prion protein-mediated neurotoxicity and mitochondrial dysfunction

Germ cell-specific sustained activation of Wnt signalling perturbs spermatogenesis in aged mice, possibly through non-coding RNAs

Granulocyte-like myeloid derived suppressor cells (G-MDSC) are increased in multiple myeloma and are driven by dysfunctional mesenchymal stem cells (MSC)

Quantitative imaging to evaluate malignant potential of IPMNs

Combining radiomic features with a miRNA classifier may improve prediction of malignant pathology for pancreatic intraductal papillary mucinous neoplasms

Low Ki67/high ATM protein expression in malignant tumors predicts favorable prognosis in a retrospective study of early stage hormone receptor positive breast cancer

Distance to Thrombus in acute middle cerebral artery stroke predicts basal ganglia infarction after mechanical thrombectomy

Unique epigenetic gene profiles define human breast cancers with poor prognosis

Clock gene Per2 as a controller of liver carcinogenesis

Pyruvate attenuates the anti-neoplastic effect of carnosine independently from oxidative phosphorylation

P-glycoprotein-mediated chemoresistance is reversed by carbonic anhydrase XII inhibitors

Correlation between serum IL-1β and miR-144-3p as well as their prognostic values in LUAD and LUSC patients

Association analysis of ANK3 gene variants with schizophrenia in a northern Chinese Han population

Genetic variants associated with gastrointestinal symptoms in Fabry disease

A regulatory loop involving miR-29c and Sp1 elevates the TGF-β1 mediated epithelial-to-mesenchymal transition in lung cancer

Glucocorticoids may compromise the effect of gefitinib in non-small cell lung cancer

Tumor-targeting Salmonella typhimurium A1-R combined with temozolomide regresses malignant melanoma with a BRAF-V600E mutation in a patient-derived orthotopic xenograft (PDOX) model

Therapy-related acute myeloid leukemia following treatment of lymphoid malignancies

Thyroid transcription factor FOXE1 interacts with ETS factor ELK1 to co-regulate TERT

Disrupted in schizophrenia 1 (DISC1) inhibits glioblastoma development by regulating mitochondria dynamics

Depression induces poor prognosis associates with the down-regulation brain derived neurotrophic factor of serum in advanced small cell lung cancer

Overexpression of FZD7 promotes glioma cell proliferation by upregulating TAZ

Cigarette smoking reduced renal function deterioration in hypertensive patients may be mediated by elevated homocysteine

Fibroblast growth factor signalling induces loss of progesterone receptor in breast cancer cells

Acidic pH reduces VEGF-mediated endothelial cell responses by downregulation of VEGFR-2; relevance for anti-angiogenic therapies

Interferon-induced transmembrane protein 1 (IFITM1) is required for the progression of colorectal cancer

The chromatin-remodeling enzyme BRG1 promotes colon cancer progression via positive regulation of WNT3A

An early-screening biomarker of endometrial carcinoma: NGAL is associated with epithelio-mesenchymal transition

Adipocytes secreted leptin is a pro-tumor factor for survival of multiple myeloma under chemotherapy

A novel highly potent trivalent TGF-β receptor trap inhibits early-stage tumorigenesis and tumor cell invasion in murine Pten-deficient prostate glands

miR-1 inhibits progression of high-risk papillomavirus-associated human cervical cancer by targeting G6PD

Newcastle disease virus employs macropinocytosis and Rab5a-dependent intracellular trafficking to infect DF-1 cells

Gli1 promotes colorectal cancer metastasis in a Foxm1-dependent manner by activating EMT and PI3K-AKT signaling

Prognostic and diagnostic potential of isocitrate dehydrogenase 1 in esophageal squamous cell carcinoma

Aberrant overexpression of ADAR1 promotes gastric cancer progression by activating mTOR/p70S6K signaling

Comprehensive analysis of aberrantly expressed profiles of lncRNAs and miRNAs with associated ceRNA network in muscle-invasive bladder cancer

NT1721, a novel epidithiodiketopiperazine, exhibits potent in vitro and in vivo efficacy against acute myeloid leukemia

Suppression of hepatic stellate cell activation through downregulation of gremlin1 expression by the miR-23b/27b cluster

Induction of the mitochondria-mediated apoptosis in human esophageal cancer cells by DS2, a newly synthetic diterpenoid analog, is regulated by Bax and caused by generation of reactive oxygen species

Nordihydroguaiaretic acid impairs prostate cancer cell migration and tumor metastasis by suppressing neuropilin 1

Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation

A promoter polymorphism in APJ gene is significantly associated with blood pressure changes and hypertension risk in Chinese women

Assessment of differentially expressed plasma microRNAs in nonsyndromic cleft palate and nonsyndromic cleft lip with cleft palate

Intratumoral heterogeneity and chemoresistance in nonseminomatous germ cell tumor of the testis

A microRNA biomarker panel for the non-invasive detection of bladder cancer

Myb expression is critical for myeloid leukemia development induced by Setbp1 activation

Inhibition of oxidative phosphorylation suppresses the development of osimertinib resistance in a preclinical model of EGFR-driven lung adenocarcinoma

Octreotide-periplocymarin conjugate prodrug for improving targetability and anti-tumor efficiency: synthesis, in vitro and in vivo evaluation

Deletion of 18q is a strong and independent prognostic feature in prostate cancer

Rad9a is required for spermatogonia differentiation in mice

An NK cell line (haNK) expressing high levels of granzyme and engineered to express the high affinity CD16 allele

Re-purposing of curcumin as an anti-metastatic agent for the treatment of epithelial ovarian cancer: in vitro model using cancer stem cell enriched ovarian cancer spheroids

No role of IFITM3 in brain tumor formation in vivo

Patient-derived glioblastoma stem cells respond differentially to targeted therapies

MYC associated zinc finger protein promotes the invasion and metastasis of hepatocellular carcinoma by inducing epithelial mesenchymal transition

Whole-exome and transcriptome sequencing of refractory diffuse large B-cell lymphoma

Inhibition of HAX-1 by miR-125a reverses cisplatin resistance in laryngeal cancer stem cells

Discovery and replication of microRNAs for breast cancer risk using genome-wide profiling

Droplet digital PCR analysis of NOTCH1 gene mutations in chronic lymphocytic leukemia

Tumors with unmethylated MLH1 and the CpG island methylator phenotype are associated with a poor prognosis in stage II colorectal cancer patients

Systematic expression analysis of the mitochondrial complex III subunits identifies UQCRC1 as biomarker in clear cell renal cell carcinoma

Chemotherapy plus dendritic cells co-cultured with cytokine-induced killer cells versus chemotherapy alone to treat advanced non-small-cell lung cancer: A meta-analysis

Altered DNA methylation in neonates born large-for-gestational-age is associated with cardiometabolic risk in children

Increasing the efficacy of radiotherapy by modulating the CCR2/CCR5 chemokine axes

Complement component 7 (C7), a potential tumor suppressor, is correlated with tumor progression and prognosis

Decreased DACH1 expression in glomerulopathy is associated with disease progression and severity

An 8-gene signature for prediction of prognosis and chemoresponse in non-small cell lung cancer

Prognostic nutritional index as a prognostic biomarker for survival in digestive system carcinomas

Elevated expression of STIM1 is involved in lung tumorigenesis

Integrating mechanisms of response and resistance against the tubulin binding agent Eribulin in preclinical models of osteosarcoma

M2 macrophages induce ovarian cancer cell proliferation via a heparin binding epidermal growth factor/matrix metalloproteinase 9 intercellular feedback loop

Associations between XRCC2 rs3218536 and ERCC2 rs13181 polymorphisms and ovarian cancer

Lactate dehydrogenase is a prognostic indicator in patients with hepatocellular carcinoma treated by sorafenib: results from the real life practice in HBV endemic area

Mouse Sirt3 promotes autophagy in AngII-induced myocardial hypertrophy through the deacetylation of FoxO1

Dysregulated human Tyrosyl-DNA phosphodiesterase I acts as cellular toxin

Gold nanoparticles delivered miR-375 for treatment of hepatocellular carcinoma

Plasma osteoprotegerin and breast cancer risk in BRCA1 and BRCA2 mutation carriers

Loss of ZG16 is regulated by miR-196a and contributes to stemness and progression of colorectal cancer

Genetic variants in the acylphosphatase 2 gene and the risk of breast cancer in a Han Chinese population

An XIST-related small RNA regulates KRAS G-quadruplex formation beyond X-inactivation

High-risk HPV genotypes and P16INK4a expression in a cohort of head and neck squamous cell carcinoma patients in Singapore

Lgr6+ stem cells and their progeny in mouse epidermis under regimens of exogenous skin carcinogenesis, and their absence in ensuing skin tumors

TRIM11, a direct target of miR-24-3p, promotes cell proliferation and inhibits apoptosis in colon cancer

Gene and microRNA modulation upon trabectedin treatment in a human intrahepatic cholangiocarcinoma paired patient derived xenograft and cell line

Prognostic value of three-dimensional echocardiographic right ventricular ejection fraction in patients with pulmonary arterial hypertension

The association of variants in PNPLA3 and GRP78 and the risk of developing hepatocellular carcinoma in an Italian population

Niclosamide and its analogs are potent inhibitors of Wnt/β-catenin, mTOR and STAT3 signaling in ovarian cancer

Peroxiredoxin 2 is essential for maintaining cancer stem cell-like phenotype through activation of Hedgehog signaling pathway in colon cancer

Genetic variants in the ZNF208 gene are associated with esophageal cancer in a Chinese Han population

IL-4, a direct target of miR-340/429, is involved in radiation-induced aggressive tumor behavior in human carcinoma cells

Epigenetic inhibition of miR-663b by long non-coding RNA HOTAIR promotes pancreatic cancer cell proliferation via up-regulation of insulin-like growth factor 2

The anti-tumor drug 2-hydroxyoleic acid (Minerval) stimulates signaling and retrograde transport

VENTX induces expansion of primitive erythroid cells and contributes to the development of acute myeloid leukemia in mice

Efficacy and safety of icotinib in treating non-small cell lung cancer: a systematic evaluation and meta-analysis based on 15 studies

Investigation of long-term survival outcomes and failure patterns of patients with nasopharyngeal carcinoma receiving intensity-modulated radiotherapy: a retrospective analysis

MicroRNA-214 protects against hypoxia/reoxygenation induced cell damage and myocardial ischemia/reperfusion injury via suppression of PTEN and Bim1 expression

Sublethal exposure to alpha radiation (²²³Ra dichloride) enhances various carcinomas’ sensitivity to lysis by antigen-specific cytotoxic T lymphocytes through calreticulin-mediated immunogenic modulation

Comparative proteomics of a model MCF10A-KRas^G12V cell line reveals a distinct molecular signature of the KRas^G12V cell surface

Overexpression of ANXA3 is an independent prognostic indicator in gastric cancer and its depletion suppresses cell proliferation and tumor growth

Hepatocyte specific expression of an oncogenic variant of β-catenin results in cholestatic liver disease

Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers

A novel fully human anti-NCL immunoRNase for triple-negative breast cancer therapy

The disintegrin echistatin in combination with doxorubicin targets high-metastatic human osteosarcoma overexpressing α_νβ₃ integrin in chick embryo and nude mouse models

CCL2/EGF positive feedback loop between cancer cells and macrophages promotes cell migration and invasion in head and neck squamous cell carcinoma

Suppression of Nestin reveals a critical role for p38-EGFR pathway in neural progenitor cell proliferation

Tracing anti-cancer and cancer-promoting actions of all-trans retinoic acid in breast cancer to a RARα epigenetic mechanism of mammary epithelial cell fate

Curcumin increases exosomal TCF21 thus suppressing exosome-induced lung cancer

MicroRNA-595 sensitizes ovarian cancer cells to cisplatin by targeting ABCB1

KIAA0247 suppresses the proliferation, angiogenesis and promote apoptosis of human glioma through inactivation of the AKT and Stat3 signaling pathway

Tag SNPs of long non-coding RNA TINCR affect the genetic susceptibility to gastric cancer in a Chinese population

Regulation of brachyury by fibroblast growth factor receptor 1 in lung cancer

RhoA regulates resistance to irinotecan by regulating membrane transporter and apoptosis signaling in colorectal cancer

Negative feedback between TAp63 and Mir-133b mediates colorectal cancer suppression

Interleukin-18 deteriorates Fabry cardiomyopathy and contributes to the development of left ventricular hypertrophy in Fabry patients with GLA IVS4+919 G>A mutation

Associations between single-nucleotide polymorphisms of human exonuclease 1 and the risk of hepatocellular carcinoma

Identification of differentially expressed genes in the development of osteosarcoma using RNA-seq

Autophagy decreases alveolar macrophage apoptosis by attenuating endoplasmic reticulum stress and oxidative stress

Suppression of osteopontin inhibits chemically induced hepatic carcinogenesis by induction of apoptosis in mice

Triple negative breast cancer development can be selectively suppressed by sustaining an elevated level of cellular cyclic AMP through simultaneously blocking its efflux and decomposition

MicroRNA-34a expression levels in serum and intratumoral tissue can predict bone metastasis in patients with hepatocellular carcinoma

Activation of endoplasmic reticulum stress and the extrinsic apoptotic pathway in human lung cancer cells by the new synthetic flavonoid, LZ-205

Repurposing the anti-malarial drug dihydroartemisinin suppresses metastasis of non-small-cell lung cancer via inhibiting NF-κB/GLUT1 axis

Identification of aberrantly expressed glycans in gastric cancer by integrated lectin microarray and mass spectrometric analyses

Identification of different ALK mutations in a pair of neuroblastoma cell lines established at diagnosis and relapse

A combination of Nottingham prognostic index and IHC4 score predicts pathological complete response of neoadjuvant chemotherapy in estrogen receptor positive breast cancer

Investigating cytokinesis failure as a strategy in cancer therapy

An efficient iterative CBCT reconstruction approach using gradient projection sparse reconstruction algorithm

Activation of chronic toxoplasmosis by transportation stress in a mouse model

Targeting protein kinase CK2 suppresses bladder cancer cell survival via the glucose metabolic pathway

Toll-like receptor 9 expression is associated with breast cancer sensitivity to the growth inhibitory effects of bisphosphonates in vitro and in vivo

Curcumin-carrying nanoparticles prevent ischemia-reperfusion injury in human renal cells

New differentially expressed genes and differential DNA methylation underlying refractory epilepsy

The synthetic lethal killing of RAD54B-deficient colorectal cancer cells by PARP1 inhibition is enhanced with SOD1 inhibition

Overexpression of Semaphorin-3E enhances pancreatic cancer cell growth and associates with poor patient survival

CLDN1 expression in cervical cancer cells is related to tumor invasion and metastasis

Midkine is a serum and urinary biomarker for the detection and prognosis of non-small cell lung cancer

Association of polymorphisms in the telomere-related gene ACYP2 with lung cancer risk in the Chinese Han population

Targeted therapy of multiple liver metastases after resected solitary gastric metastasis and primary pulmonary adenocarcinoma

A characteristic biosignature for discrimination of gastric cancer from healthy population by high throughput GC-MS analysis

Meta-analysis of bariatric surgery versus non-surgical treatment for type 2 diabetes mellitus

Radiofrequency ablation versus ¹²⁵I-seed brachytherapy for painful metastases involving the bone

Poorer breast cancer survival outcomes in males than females might be attributable to tumor subtype