Vol 8, No 47

Intentional weight loss and cancer risk

Community mining of open clinical trial data

Novel function of the tumor suppressor PML at ER-mitochondria sites in the control of autophagy

Taking it up a NOTCH: anovel subgroup of ACC is identified

Eph receptors as oncotargets

‘ILC-poiesis’: generating tissue ILCs from naïve precursors

Immune-DDR crosstalk in pre-leukemia stem cells

UCB HCT in FLT3+ AML

Importance of FISH genetics in light chain amyloidosis

Stromal cyclin D1 promotes heterotypic immune signaling and breast cancer growth

Anti-pancreatic cancer activity of ONC212 involves the unfolded protein response (UPR) and is reduced by IGF1-R and GRP78/BIP

PI3Kδ inhibition causes feedback activation of PI3Kα in the ABC subtype of diffuse large B-cell lymphoma

Circular RNA expression profile and potential function of hsa_circRNA_101238 in human thoracic aortic dissection

The neglected avian hepatotropic virus induces acute and chronic hepatitis in ducks: an alternative model for hepatology

A native-like bispecific antibody suppresses the inflammatory cytokine response by simultaneously neutralizing tumor necrosis factor-alpha and interleukin-17A

Activation of VIP signaling enhances immunosuppressive effect of MDSCs on CMV-induced adaptive immunity

A keratinocyte life cycle model identifies novel host genome regulation by human papillomavirus 16 relevant to HPV positive head and neck cancer

Integration of metabolomics, transcriptomics, and microRNA expression profiling reveals a miR-143-HK2-glucose network underlying zinc-deficiency-associated esophageal neoplasia

Outcome of patients treated for myelodysplastic syndromes with 5q deletion after failure of lenalidomide therapy

The AF4-MLL fusion transiently augments multilineage hematopoietic engraftment but is not sufficient to initiate leukemia in cord blood CD34⁺ cells

The significance of post-translational removal of α-DG-N in early stage endometrial cancer development

The nucleocytoplasmic translocation and up-regulation of ING5 protein in breast cancer: a potential target for gene therapy

Cryoablation combined with allogenic natural killer cell immunotherapy improves the curative effect in patients with advanced hepatocellular cancer

Significance of NLDA, the commixed index of inflammation, immune responses, hemostasis, and nutrition, for predicting metastatic non-small cell lung cancer prognosis and metastases

Transcriptome profiling in preadipocytes identifies long noncoding RNAs as Sam68 targets

Mutational re-modeling of di-aspartyl intramembrane proteases: uncoupling physiologically-relevant activities from those associated with Alzheimer’s disease

ERK inhibition sensitizes CZ415-induced anti-osteosarcoma activity in vitro and in vivo

Immune profiling of NF1-associated tumors reveals histologic subtype distinctions and heterogeneity: Implications for immunotherapy

Ionising radiation increases permeability of endothelium through ADAM10-mediated cleavage of VE-cadherin

MicroRNA-423-5p facilitates hypoxia/reoxygenation-induced apoptosis in renal proximal tubular epithelial cells by targeting GSTM1 via endoplasmic reticulum stress

Associations between polymorphisms in the IL-4 gene and renal cell carcinoma in Chinese Han population

Apigenin sensitizes BEL-7402/ADM cells to doxorubicin through inhibiting miR-101/Nrf2 pathway

The influence of marital status on survival in patients with oral tongue squamous cell carcinoma

Association of striking life events with primary breast cancer in 265 Chinese women: a case-control study

Endoscopic retrograde cholangiopancreatography versus laparoscopic exploration for common bile duct stones in post-cholecystectomy patients: a retrospective study

Molecular chaperones in the acquisition of cancer cell chemoresistance with mutated TP53 and MDM2 up-regulation

Exportin 1 (XPO1) inhibition leads to restoration of tumor suppressor miR-145 and consequent suppression of pancreatic cancer cell proliferation and migration

A novel mutation R190H in the AT-hook 1 domain of MeCP2 identified in an atypical Rett syndrome

G-T haplotype established by rs3785889-rs16941382 in GOSR2 gene is associated with coronary artery disease in Chinese Han population

Quaking-5 suppresses aggressiveness of lung cancer cells through inhibiting β-catenin signaling pathway

Potential genotoxic and cytotoxicity of emamectin benzoate in human normal liver cells

QiShenYiQi pill attenuates atherosclerosis by promoting regulatory T cells, inhibiting T helper 17 cells and accelerating cholesterol excretion

Kaempferol induces hepatocellular carcinoma cell death via endoplasmic reticulum stress-CHOP-autophagy signaling pathway

Aberrantly activated Cox-2 and Wnt signaling interact to maintain cancer stem cells in glioblastoma

Iron-responsive element-binding protein 2 plays an essential role in regulating prostate cancer cell growth

Pathologic subtype-defined prognosis is dependent on both tumor stage and status of oncogenic driver mutations in lung adenocarcinoma

Enhanced response of melanoma cells to MEK inhibitors following unbiased IGF-1R down-regulation

Disease spectrum of abnormal serum free light chain ratio and its diagnostic significance

Melatonin suppresses hepatocellular carcinoma progression via lncRNA-CPS1-IT-mediated HIF-1α inactivation

Preoperative chemoradiotherapy for rectal cancer: the sensitizer role of the association between miR-375 and c-Myc

c-Met, CREB1 and EGFR are involved in miR-493-5p inhibition of EMT via AKT/GSK-3β/Snail signaling in prostate cancer

Correlation of placental microbiota with fetal macrosomia and clinical characteristics in mothers and newborns

Tumacrophage: macrophages transformed into tumor stem-like cells by virulent genetic material from tumor cells

Understanding the mechanism of binding between Gab2 and the C terminal SH3 domain from Grb2

Local blockage of self-sustainable erythropoietin signaling suppresses tumor progression in non-small cell lung cancer

Human mesenchymal stem cells ameliorate experimental pulmonary hypertension induced by maternal inflammation and neonatal hyperoxia in rats

Environmental conditions differentially affect neurobehavioral outcomes in a mouse model of sepsis-associated encephalopathy

Immunological cytokine profiling identifies TNF-α as a key molecule dysregulated in autistic children

Programmed death ligand-1 and MET co-expression is a poor prognostic factor in gastric cancers after resection

Effective protection against acute respiratory distress syndrome/sepsis injury by combined adipose-derived mesenchymal stem cells and preactivated disaggregated platelets

Vinculin and filamin-C are two potential prognostic biomarkers and therapeutic targets for prostate cancer cell migration

Potential clinical value of PET/CT in predicting occult nodal metastasis in T1-T2N0M0 lung cancer patients staged by PET/CT

Ningnanmycin inhibits tobacco mosaic virus virulence by binding directly to its coat protein discs

Comprehensive microRNA-sequencing of exosomes derived from head and neck carcinoma cells in vitro reveals common secretion profiles and potential utility as salivary biomarkers

Implications of mutational spectrum in myelodysplastic syndromes based on targeted next-generation sequencing

PPARγ sumoylation-mediated lipid accumulation in lung cancer

Hic-5 regulates epithelial to mesenchymal transition in ovarian cancer cells in a TGFβ1-independent manner

Functional polymorphisms in the promoter region of miR-17-92 cluster are associated with a decreased risk of colorectal cancer

C1q/Tumor necrosis factor-related protein-3 protects macrophages against LPS-induced lipid accumulation, inflammation and phenotype transition via PPARγ and TLR4-mediated pathways

Treatment strategy and prognostic factors for Krukenberg tumors of gastric origin: report of a 10-year single-center experience from China

Genetic and immune features of resectable malignant brainstem gliomas

Fibroblast growth factor modulates mast cell recruitment in a murine model of prostate cancer

N-myc downstream-regulated gene 1 promotes apoptosis in colorectal cancer via up-regulating death receptor 4

Elevated TIMP-1 expression is associated with a prometastatic phenotype, disease relapse, and poor survival in neuroblastoma

Lingguizhugan decoction improves non-alcoholic fatty liver disease by altering insulin resistance and lipid metabolism related genes: a whole trancriptome study by RNA-Seq

Expression of protein kinase A and the kappa opioid receptor in selected brain regions and conditioned place aversion in morphine-dependent rats

The clinicopathological significance and prognostic value of EMMPRIN overexpression in cancers: evidence from 39 cohort studies

The clinical significance of c-Kit mutations in metastatic oral mucosal melanoma in China

Identification of novel genetic regulations associated with airway epithelial homeostasis using next-generation sequencing data and bioinformatics approaches

Immunoprevention of KRAS-driven lung adenocarcinoma by a multipeptide vaccine

Clinical outcome of dynamic hip locking plates and proximal femoral nails anti-rotation-Asia for treating intertrochanteric femur fracture with lateral wall fractures in the elder patients

Early detection of thymidylate synthase resistance in non-small cell lung cancer with FLT-PET imaging

Probably less than one-tenth of the genes produce only the wild type protein without at least one additional protein isoform in some human cancer cell lines

ING4 expressing oncolytic vaccinia virus promotes anti-tumor efficiency and synergizes with gemcitabine in pancreatic cancer

Tumor-expressed immune checkpoint B7x promotes cancer progression and antigen-specific CD8 T cell exhaustion and suppressive innate immune cells

PATZ1 knockdown enhances malignant phenotype in thyroid epithelial follicular cells and thyroid cancer cells

Antitumor efficacy of triple monoclonal antibody inhibition of epidermal growth factor receptor (EGFR) with MM151 in EGFR-dependent and in cetuximab-resistant human colorectal cancer cells

Functional and non-functional pancreatic neuroendocrine tumours: ENETS or AJCC TNM staging system?

The association between CCR5 Δ32 polymorphism and susceptibility to breast cancer

Monocarboxylate transporter 1 (MCT1), a tool to stratify acute myeloid leukemia (AML) patients and a vehicle to kill cancer cells

miR-93-3p inhibition suppresses clear cell renal cell carcinoma proliferation, metastasis and invasion

MMP9 polymorphism is associated with susceptibility to non-traumatic osteonecrosis of femoral head in a Chinese Han population

Reversal of 5-fluorouracil resistance by EGCG is mediate by inactivation of TFAP2A/VEGF signaling pathway and down-regulation of MDR-1 and P-gp expression in gastric cancer

MicroRNA-23a promotes pancreatic cancer metastasis by targeting epithelial splicing regulator protein 1

Anti-proliferative and pro-apoptotic effects induced by simultaneous inactivation of HER1 and HER2 through endogenous polyclonal antibodies

Ex vivo evaluation of tumor cell specific drug responses in malignant pleural effusions

Crenolanib is a type I tyrosine kinase inhibitor that inhibits mutant KIT D816 isoforms prevalent in systemic mastocytosis and core binding factor leukemia

Neurofibromatosis type-1 is a prognostic indicator in human gastric carcinoma

RNA-seq reveals distinctive RNA profiles of small extracellular vesicles from different human liver cancer cell lines

Lack of both androgen receptor and forkhead box A1 (FOXA1) expression is a poor prognostic factor in estrogen receptor-positive breast cancers

Protective effects of sulforaphane on di-n-butylphthalate-induced testicular oxidative stress injury in male mice offsprings via activating Nrf2/ARE pathway

RRS1 silencing suppresses colorectal cancer cell proliferation and tumorigenesis by inhibiting G2/M progression and angiogenesis

Mcl-1 stabilization confers resistance to taxol in human gastric cancer

miR-27a-3p targeting RXRα promotes colorectal cancer progression by activating Wnt/β-catenin pathway

Effects of growth hormone on cardiac remodeling and soleus muscle in rats with aortic stenosis-induced heart failure

A phase II study of S-1 with concurrent radiotherapy in elderly patients with esophageal cancer

The role of indoxyl sulfate in renal anemia in patients with chronic kidney disease

The c-jun N-terminal kinase plays a key role in ocular degenerative changes in a mouse model of Alzheimer disease suggesting a correlation between ocular and brain pathologies

NVP-BKM120 inhibits colon cancer growth via FoxO3a-dependent PUMA induction

Loss of BRCA1 promotor hypermethylation in recurrent high-grade ovarian cancer

RLIM suppresses hepatocellular carcinogenesis by up-regulating p15 and p21

Overexpression of carbonic anhydrase IX induces cell motility by activating matrix metalloproteinase-9 in human oral squamous cell carcinoma cells

Regulation of FBXO4-mediated ICAM-1 protein stability in metastatic breast cancer

Trends of long noncoding RNA research from 2007 to 2016: a bibliometric analysis

Development of a radiolabeled caninized anti-EGFR antibody for comparative oncology trials

Virtual screening approach to identifying influenza virus neuraminidase inhibitors using molecular docking combined with machine-learning-based scoring function

HDAC inhibitors enhance the immunotherapy response of melanoma cells

Long noncoding RNA XIST is a prognostic factor in colorectal cancer and inhibits 5-fluorouracil-induced cell cytotoxicity through promoting thymidylate synthase expression

Preoperative chronic kidney disease predicts poor oncological outcomes after radical nephroureterectomy in patients with upper urinary tract urothelial carcinoma

The coffee diterpene kahweol enhances sensitivity to sorafenib in human renal carcinoma Caki cells through down-regulation of Mcl-1 and c-FLIP expression

Inhibition of cell cycle progression by the hydroxytyrosol–cetuximab combination yields enhanced chemotherapeutic efficacy in colon cancer cells

Alcohol consumption and gastric cancer risk: a meta-analysis of prospective cohort studies

Effect of long non-coding RNA highly up-regulated in liver cancer (HULC) on the prognosis of cancer: A meta-analysis

Meta-analysis of differences in Constant-Murley scores for three mid-shaft clavicular fracture treatments

Prognostic role of tumour-associated macrophages and macrophage scavenger receptor 1 in prostate cancer: a systematic review and meta-analysis

Clinicopathological significance of the p16 hypermethylation in multiple myeloma, a systematic review and meta-analysis

Incidence and relative risk of cutaneous squamous cell carcinoma with single-agent BRAF inhibitor and dual BRAF/MEK inhibitors in cancer patients: a meta-analysis

Prognostic value of lncRNAs in lung carcinoma: a meta-analysis

Red and processed meat consumption and colorectal cancer risk: a systematic review and meta-analysis

Safety of the neprilysin/renin-angiotensin system inhibitor LCZ696

Antiandrogenic and antimineralocorticoid health benefits of COC containing newer progestogens: dienogest and drospirenone