Oncotarget

Vol 8, No 41

September 19, 2017

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About The Cover

The cover for issue 41 of Oncotarget features Figure 7E, "Schema depicting the proposed involvement of MUC1-C in driving expression of the PRC1 components, BMI1, RING2 and RING1," from Tagde, et al.

Table of Contents

Editorial

Neurobiological insights from bioluminescence imaging

Neurobiological insights from bioluminescence imaging

https://doi.org/10.18632/oncotarget.20302

Markus Aswendt, Franziska Melanie Collmann,  and Mathias Hoehn
69198-69199
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Salvage therapy for relapsed testicular cancer

Salvage therapy for relapsed testicular cancer

https://doi.org/10.18632/oncotarget.20573

Nabil Adra,  and Lawrence H. Einhorn
69200-69201
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Bioresorbable vascular scaffolds: between promises and reality

Bioresorbable vascular scaffolds: between promises and reality

https://doi.org/10.18632/oncotarget.20630

Rocco A. Montone, Adam J. Brown,  and Giampaolo Niccoli
69202-69203
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Priority Research Papers

mTORC1/autophagy-regulated MerTK in mutant BRAFV600 melanoma with acquired resistance to BRAF inhibition

mTORC1/autophagy-regulated MerTK in mutant BRAFV600 melanoma with acquired resistance to BRAF inhibition

https://doi.org/10.18632/oncotarget.18213

Gongda Xue, Reto Kohler, Fengyuan Tang, Debby Hynx, Yuhua Wang, Francesca Orso, Vincent Prêtre, Reto Ritschard, Petra Hirschmann, Peter Cron, Tim Roloff, Reinhard Dummer, Mario Mandalà, Sandrine Bichet, Christel Genoud, Alexandra G. Meyer, Manuele G. Muraro, Giulio C. Spagnoli, Daniela Taverna, Curzio Rüegg, Taha Merghoub, Daniela Massi, Huifang Tang, Mitchell P. Levesque, Stephan Dirnhofer, Alfred Zippelius, Brian A. Hemmings,  and Andreas Wicki
69204-69218
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Pre-clinical pharmacology of AZD3965, a selective inhibitor of MCT1: DLBCL, NHL and Burkitt’s lymphoma anti-tumor activity

Pre-clinical pharmacology of AZD3965, a selective inhibitor of MCT1: DLBCL, NHL and Burkitt’s lymphoma anti-tumor activity

https://doi.org/10.18632/oncotarget.18215

Nicola J. Curtis, Lorraine Mooney, Lorna Hopcroft, Filippos Michopoulos, Nichola Whalley, Haihong Zhong, Clare Murray, Armelle Logie, Mitchell Revill, Kate F. Byth, Amanda D. Benjamin, Mike A. Firth, Stephen Green, Paul D. Smith,  and Susan E. Critchlow
69219-69236
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting MUC1-C suppresses polycomb repressive complex 1 in multiple myeloma

Targeting MUC1-C suppresses polycomb repressive complex 1 in multiple myeloma

https://doi.org/10.18632/oncotarget.20144

Ashujit Tagde, Tahireh Markert, Hasan Rajabi, Masayuki Hiraki, Maroof Alam, Audrey Bouillez, David Avigan, Kenneth Anderson,  and Donald Kufe
69237-69249
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HTLV-1 viral oncogene HBZ induces osteolytic bone disease in transgenic mice

HTLV-1 viral oncogene HBZ induces osteolytic bone disease in transgenic mice

https://doi.org/10.18632/oncotarget.20565

Alison K. Esser, Daniel A. Rauch, Jingyu Xiang, John C. Harding, Nicole A. Kohart, Michael H. Ross, Xinming Su, Kevin Wu, Devra Huey, Yalin Xu, Kiran Vij, Patrick L. Green, Thomas J. Rosol, Stefan Niewiesk, Lee Ratner,  and Katherine N. Weilbaecher
69250-69263
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Phosphodiesterase 10A is overexpressed in lung tumor cells and inhibitors selectively suppress growth by blocking β-catenin and MAPK signaling

Phosphodiesterase 10A is overexpressed in lung tumor cells and inhibitors selectively suppress growth by blocking β-catenin and MAPK signaling

https://doi.org/10.18632/oncotarget.20566

Bing Zhu, Ashley Lindsey, Nan Li, Kevin Lee, Veronica Ramirez-Alcantara, Joshua C. Canzoneri, Alexandra Fajardo, Luciana Madeira da Silva, Meagan Thomas, John T. Piazza, Larry Yet, Brian T. Eberhardt, Evrim Gurpinar, Dennis Otali, William Grizzle, Jacob Valiyaveettil, Xi Chen, Adam B. Keeton,  and Gary A. Piazza
69264-69280
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Loss of Egr1, a human del5q gene, accelerates BCR-ABL driven chronic myelogenous leukemia

Loss of Egr1, a human del5q gene, accelerates BCR-ABL driven chronic myelogenous leukemia

https://doi.org/10.18632/oncotarget.20612

Silvia Maifrede, Andrew Magimaidas, Xiaojin Sha, Kaushiki Mukherjee, Dan A. Liebermann,  and Barbara Hoffman
69281-69294
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Irreversible growth plate fusions in children with medulloblastoma treated with a targeted hedgehog pathway inhibitor

Irreversible growth plate fusions in children with medulloblastoma treated with a targeted hedgehog pathway inhibitor

https://doi.org/10.18632/oncotarget.20619

Giles W. Robinson, Sue C. Kaste, Wassim Chemaitilly, Daniel C. Bowers, Stephen Laughton, Amy Smith, Nicholas Gottardo, Sonia Partap, Anne Bendel, Karen D. Wright, Brent A. Orr, William C. Warner, Arzu Onar-Thomas,  and Amar Gajjar
69295-69302
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Research Papers: Gerotarget (Focus on Aging)

Catalpol protects synaptic proteins from beta-amyloid induced neuron injury and improves cognitive functions in aged rats

Catalpol protects synaptic proteins from beta-amyloid induced neuron injury and improves cognitive functions in aged rats

https://doi.org/10.18632/oncotarget.17951

Zhiming Xia, Fengfei Wang, Shuang Zhou, Rui Zhang, Fushun Wang, Jason H. Huang, Erxi Wu, Yongfang Zhang,  and Yaer Hu
69303-69315
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Wnt/β-catenin signaling promotes aging-associated hair graying in mice

Wnt/β-catenin signaling promotes aging-associated hair graying in mice

https://doi.org/10.18632/oncotarget.20613

Zhihui Zhang, Mingxing Lei, Haoran Xin, Chunyan Hu, Tian Yang, Yizhan Xing, Yuhong Li, Haiying Guo, Xiaohua Lian,  and Fang Deng
69316-69327
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Caloric restriction extends yeast chronological lifespan via a mechanism linking cellular aging to cell cycle regulation, maintenance of a quiescent state, entry into a non-quiescent state and survival in the non-quiescent state

Caloric restriction extends yeast chronological lifespan via a mechanism linking cellular aging to cell cycle regulation, maintenance of a quiescent state, entry into a non-quiescent state and survival in the non-quiescent state

https://doi.org/10.18632/oncotarget.20614

Anna Leonov, Rachel Feldman, Amanda Piano, Anthony Arlia-Ciommo, Vicky Lutchman, Masoumeh Ahmadi, Sarah Elsaser, Hana Fakim, Mahdi Heshmati-Moghaddam, Asimah Hussain, Sandra Orfali, Harshvardhan Rajen, Negar Roofigari-Esfahani, Leana Rosanelli,  and Vladimir I. Titorenko
69328-69350
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HIF-1α:CRAT:miR-144-3p axis dysregulation promotes osteoarthritis chondrocyte apoptosis and VLCFA accumulation

HIF-1α:CRAT:miR-144-3p axis dysregulation promotes osteoarthritis chondrocyte apoptosis and VLCFA accumulation

https://doi.org/10.18632/oncotarget.20615

Jinsoo Song, Yeon-Ho Kang, Sik Yoon, Churl-Hong Chun,  and Eun-Jung Jin
69351-69361
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Handgrip strength and subclinical carotid atherosclerosis in relation to platelet levels among hypertensive elderly Japanese

Handgrip strength and subclinical carotid atherosclerosis in relation to platelet levels among hypertensive elderly Japanese

https://doi.org/10.18632/oncotarget.20618

Yuji Shimizu, Shimpei Sato, Jun Koyamatsu, Hirotomo Yamanashi, Mako Nagayoshi, Koichiro Kadota, Shin-Ya Kawashiri, Keita Inoue, Yasuhiro Nagata,  and Takahiro Maeda
69362-69369
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Astaxanthin acts via LRP-1 to inhibit inflammation and reverse lipopolysaccharide-induced M1/M2 polarization of microglial cells

Astaxanthin acts via LRP-1 to inhibit inflammation and reverse lipopolysaccharide-induced M1/M2 polarization of microglial cells

https://doi.org/10.18632/oncotarget.20628

Xiaojun Wen, Lijiao Xiao, Zhuoyan Zhong, Limin Wang, Ze Li, Xiaoping Pan,  and Zhonglin Liu
69370-69385
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Research Papers: Pathology

Silibinin attenuates radiation-induced intestinal fibrosis and reverses epithelial-to-mesenchymal transition

Silibinin attenuates radiation-induced intestinal fibrosis and reverses epithelial-to-mesenchymal transition

https://doi.org/10.18632/oncotarget.20624

Joong Sun Kim, Na-Kyung Han, Sung-Ho Kim,  and Hae-June Lee
69386-69397
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Research Papers: Immunology

Recombination activating gene-2null severe combined immunodeficient pigs and mice engraft human induced pluripotent stem cells differently

Recombination activating gene-2null severe combined immunodeficient pigs and mice engraft human induced pluripotent stem cells differently

https://doi.org/10.18632/oncotarget.20626

Yun-Jung Choi, EunSu Kim, Abu Musa Md Talimur Reza, Kwonho Hong, Hyuk Song, Chankyu Park, Seong-Keun Cho, Kiho Lee, Randall S. Prather,  and Jin-Hoi Kim
69398-69407
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Research Papers

Serum protein fingerprinting by PEA immunoassay coupled with a pattern-recognition algorithms distinguishes MGUS and multiple myeloma

Serum protein fingerprinting by PEA immunoassay coupled with a pattern-recognition algorithms distinguishes MGUS and multiple myeloma

https://doi.org/10.18632/oncotarget.11242

Petra Schneiderova, Tomas Pika, Petr Gajdos, Regina Fillerova, Pavel Kromer, Milos Kudelka, Jiri Minarik, Tomas Papajik, Vlastimil Scudla,  and Eva Kriegova
69408-69421
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prox1 represses IL-2 gene expression by interacting with NFAT2

Prox1 represses IL-2 gene expression by interacting with NFAT2

https://doi.org/10.18632/oncotarget.17278

Shujie Zhang, Ning Yu, Linfang Wang, Yanfeng Liu, Yuying Kong, Jing Liu,  and Youhua Xie
69422-69434
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Proteomics analysis of bladder cancer invasion: Targeting EIF3D for therapeutic intervention

Proteomics analysis of bladder cancer invasion: Targeting EIF3D for therapeutic intervention

https://doi.org/10.18632/oncotarget.17279

Agnieszka Latosinska, Marika Mokou, Manousos Makridakis, William Mullen, Jerome Zoidakis, Vasiliki Lygirou, Maria Frantzi, Ioannis Katafigiotis, Konstantinos Stravodimos, Marie C. Hupe, Maciej Dobrzynski, Walter Kolch, Axel S. Merseburger, Harald Mischak, Maria G. Roubelakis,  and Antonia Vlahou
69435-69455
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High number of chromosomal copy number aberrations inversely relates to t(11;19)(q21;p13) translocation status in mucoepidermoid carcinoma of the salivary glands

High number of chromosomal copy number aberrations inversely relates to t(11;19)(q21;p13) translocation status in mucoepidermoid carcinoma of the salivary glands

https://doi.org/10.18632/oncotarget.17282

Johannes H. Matse, Enno C.I. Veerman, Jan G.M. Bolscher, C. René Leemans, Bauke Ylstra,  and Elisabeth Bloemena
69456-69464
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Triterpenoids from Aglaia abbreviata exert cytotoxicity and multidrug resistant reversal effect in MCF-7/ADM cells via reactive oxygen species induction and P-glycoprotein inhibition

Triterpenoids from Aglaia abbreviata exert cytotoxicity and multidrug resistant reversal effect in MCF-7/ADM cells via reactive oxygen species induction and P-glycoprotein inhibition

https://doi.org/10.18632/oncotarget.17287

Juan Cen, Beibei Zheng, Rubing Bai, Li Zhang, Feng Zhang,  and Xia Zhang
69465-69476
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

BRAF/MEK inhibitors promote CD47 expression that is reversible by ERK inhibition in melanoma

BRAF/MEK inhibitors promote CD47 expression that is reversible by ERK inhibition in melanoma

https://doi.org/10.18632/oncotarget.17704

Fen Liu, Chen Chen Jiang, Xu Guang Yan, Hsin-Yi Tseng, Chun Yan Wang, Yuan Yuan Zhang, Hamed Yari, Ting La, Margaret Farrelly, Su Tang Guo, Rick F. Thorne, Lei Jin, Qi Wang,  and Xu Dong Zhang
69477-69492
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Preclinical characterization of abemaciclib in hormone receptor positive breast cancer

Preclinical characterization of abemaciclib in hormone receptor positive breast cancer

https://doi.org/10.18632/oncotarget.17778

Raquel Torres-Guzmán, Bruna Calsina, Ana Hermoso, Carmen Baquero, Beatriz Alvarez, Joaquín Amat, Ann M. McNulty, Xueqian Gong, Karsten Boehnke, Jian Du, Alfonso de Dios, Richard P. Beckmann, Sean Buchanan,  and María José Lallena
69493-69507
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Characterization of a novel androgen receptor (AR) coregulator RIPK1 and related chemicals that suppress AR-mediated prostate cancer growth via peptide and chemical screening

Characterization of a novel androgen receptor (AR) coregulator RIPK1 and related chemicals that suppress AR-mediated prostate cancer growth via peptide and chemical screening

https://doi.org/10.18632/oncotarget.17843

Cheng-Lung Hsu, Jai-Shin Liu, Ting-Wei Lin, Ying-Hsu Chang, Yung-Chia Kuo, An-Chi Lin, Huei-Ju Ting, See-Tong Pang, Li-Yu Lee, Wen-Lung Ma, Chun-Cheng Lin,  and Wen-Guey Wu
69508-69519
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PDGFRA, HSD17B4 and HMGB2 are potential therapeutic targets in polycystic ovarian syndrome and breast cancer

PDGFRA, HSD17B4 and HMGB2 are potential therapeutic targets in polycystic ovarian syndrome and breast cancer

https://doi.org/10.18632/oncotarget.17846

Huiyu Xu, Yong Han, Jiaying Lou, Hongxian Zhang, Yue Zhao, Balázs Győrffy,  and Rong Li
69520-69526
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Beneficial effect of fluoxetine treatment aganist psychological stress is mediated by increasing BDNF expression in selected brain areas

Beneficial effect of fluoxetine treatment aganist psychological stress is mediated by increasing BDNF expression in selected brain areas

https://doi.org/10.18632/oncotarget.17891

Gongying Li, Ping Jing, Zhidong Liu, Zhiruo Li, Hongxia Ma, Wenzhen Tu, Wei Zhang,  and Chuanjun Zhuo
69527-69537
Abstract  |  PDF  |  HTML  |  Order a Reprint

MiR-23a promotes TGF-β1-induced EMT and tumor metastasis in breast cancer cells by directly targeting CDH1 and activating Wnt/β-catenin signaling

MiR-23a promotes TGF-β1-induced EMT and tumor metastasis in breast cancer cells by directly targeting CDH1 and activating Wnt/β-catenin signaling

https://doi.org/10.18632/oncotarget.18422

Fei Ma, Wenjie Li, Chunxiao Liu, Wei Li, Haining Yu, Bo Lei, Yanlv Ren, Zhigao Li, Da Pang,  and Cheng Qian
69538-69550
Abstract  |  PDF  |  HTML  |  Order a Reprint

Secreted miR-210-3p as non-invasive biomarker in clear cell renal cell carcinoma

Secreted miR-210-3p as non-invasive biomarker in clear cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.18449

Vincenzo Petrozza, Antonio Luigi Pastore, Giovanni Palleschi, Claudia Tito, Natale Porta, Serena Ricci, Chiara Marigliano, Manuela Costantini, Giuseppe Simone, Angelina Di Carlo, Michele Gallucci, Antonio Carbone,  and Francesco Fazi
69551-69558
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

HCaRG/COMMD5 inhibits ErbB receptor-driven renal cell carcinoma

HCaRG/COMMD5 inhibits ErbB receptor-driven renal cell carcinoma

https://doi.org/10.18632/oncotarget.18012

Hiroyuki Matsuda, Carole G. Campion, Kyoko Fujiwara, Jin Ikeda, Suzanne Cossette, Thomas Verissimo, Maiko Ogasawara, Louis Gaboury, Kosuke Saito, Kenya Yamaguchi, Satoru Takahashi, Morito Endo, Noboru Fukuda, Masayoshi Soma, Pavel Hamet,  and Johanne Tremblay
69559-69576
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cross-talk mechanism between endothelial cells and hepatocellular carcinoma cells via growth factors and integrin pathway promotes tumor angiogenesis and cell migration

Cross-talk mechanism between endothelial cells and hepatocellular carcinoma cells via growth factors and integrin pathway promotes tumor angiogenesis and cell migration

https://doi.org/10.18632/oncotarget.18632

Tang Feng, Hongchi Yu, Qing Xia, Yunlong Ma, Hongmei Yin, Yang Shen,  and Xiaoheng Liu
69577-69593
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of two novel biomarkers of rectal carcinoma progression and prognosis via co-expression network analysis

Identification of two novel biomarkers of rectal carcinoma progression and prognosis via co-expression network analysis

https://doi.org/10.18632/oncotarget.18646

Min Sun, Taojiao Sun, Zhongshi He,  and Bin Xiong
69594-69609
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mutation landscape and intra-tumor heterogeneity of two MANECs of the esophagus revealed by multi-region sequencing

Mutation landscape and intra-tumor heterogeneity of two MANECs of the esophagus revealed by multi-region sequencing

https://doi.org/10.18632/oncotarget.18678

Wenqing Yuan, Zhen Liu, Wanjun Lei, Li Sun, Haijun Yang, Yu Wang, Shweta Ramdas, Xiao Dong, Ruiping Xu, Hong Cai, Jun Z. Li,  and Yang Ke
69610-69621
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ESE-1/ELF3 mRNA expression associates with poor survival outcomes in HER2+ breast cancer patients and is critical for tumorigenesis in HER2+ breast cancer cells

ESE-1/ELF3 mRNA expression associates with poor survival outcomes in HER2+ breast cancer patients and is critical for tumorigenesis in HER2+ breast cancer cells

https://doi.org/10.18632/oncotarget.18710

Adwitiya Kar,  and Arthur Gutierrez-Hartmann
69622-69640
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A potential panel of two-long non-coding RNA signature to predict recurrence of patients with laryngeal cancer

A potential panel of two-long non-coding RNA signature to predict recurrence of patients with laryngeal cancer

https://doi.org/10.18632/oncotarget.18751

Zhigang Bai, Enhong Shi, Qiwei Wang, Zhouwei Dong,  and Ping Xu
69641-69650
Abstract  |  PDF  |  HTML  |  Order a Reprint

A phase I study of foretinib plus erlotinib in patients with previously treated advanced non-small cell lung cancer: Canadian cancer trials group IND.196

A phase I study of foretinib plus erlotinib in patients with previously treated advanced non-small cell lung cancer: Canadian cancer trials group IND.196

https://doi.org/10.18632/oncotarget.18753

Natasha B. Leighl, Ming-Sound Tsao, Geoffrey Liu, Dongsheng Tu, Cheryl Ho, Frances A. Shepherd, Nevin Murray, John R. Goffin, Garth Nicholas, Shingo Sakashita, Zhuo Chen, Lucia Kim, Jean Powers, Lesley Seymour, Glenwood Goss,  and Penelope A. Bradbury
69651-69662
Abstract  |  PDF  |  HTML  |  Order a Reprint

Progressive modulation of the human olfactory bulb transcriptome during Alzheimer´s disease evolution: novel insights into the olfactory signaling across proteinopathies

Progressive modulation of the human olfactory bulb transcriptome during Alzheimer´s disease evolution: novel insights into the olfactory signaling across proteinopathies

https://doi.org/10.18632/oncotarget.18193

Mercedes Lachen-Montes, María Victoria Zelaya, Víctor Segura, Joaquín Fernández-Irigoyen,  and Enrique Santamaría
69663-69679
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinicopathological characteristics and survival outcomes of male breast cancer according to race: A SEER population-based study

Clinicopathological characteristics and survival outcomes of male breast cancer according to race: A SEER population-based study

https://doi.org/10.18632/oncotarget.18265

He-Fen Sun, Yang Zhao, Shui-Ping Gao, Liang-Dong Li, Wen-Yan Fu, Hong-Lin Jiang, Meng-Ting Chen, Li-Peng Yang,  and Wei Jin
69680-69690
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A small-molecule inhibitor targeting the AURKC–IκBα interaction decreases transformed growth of MDA-MB-231 breast cancer cells

A small-molecule inhibitor targeting the AURKC–IκBα interaction decreases transformed growth of MDA-MB-231 breast cancer cells

https://doi.org/10.18632/oncotarget.18883

Eun Hee Han, Jin-Young Min, Shin-Ae Yoo, Sung-Joon Park, Yun-Jeong Choe, Hee Sub Yun, Zee-Won Lee, Sun Woo Jin, Hyung Gyun Kim, Hye Gwang Jeong, Hyun Kyoung Kim, Nam Doo Kim,  and Young-Ho Chung
69691-69708
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ethnic heterogeneity and prostate cancer mortality in Hispanic/Latino men: a population-based study

Ethnic heterogeneity and prostate cancer mortality in Hispanic/Latino men: a population-based study

https://doi.org/10.18632/oncotarget.19068

Felix M. Chinea, Vivek N. Patel, Deukwoo Kwon, Narottam Lamichhane, Chris Lopez, Sanoj Punnen, Erin N. Kobetz, Matthew C. Abramowitz,  and Alan Pollack
69709-69721
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Downregulation of lncRNA MEG3 and miR-770-5p inhibit cell migration and proliferation in Hirschsprung’s disease

Downregulation of lncRNA MEG3 and miR-770-5p inhibit cell migration and proliferation in Hirschsprung’s disease

https://doi.org/10.18632/oncotarget.19207

Hongxing Li, Bo Li, Dongmei Zhu, Hua Xie, Chunxia Du, Yankai Xia,  and Weibing Tang
69722-69730
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Modulation of the Nur77-Bcl-2 apoptotic pathway by p38α MAPK

Modulation of the Nur77-Bcl-2 apoptotic pathway by p38α MAPK

https://doi.org/10.18632/oncotarget.19227

Jie Liu, Guang-Hui Wang, Ying-Hui Duan, Yi Dai, Yuzhou Bao, Mengjie Hu, Yu-Qi Zhou, Mingyu Li, Fuquan Jiang, Hu Zhou, Xin-Sheng Yao,  and Xiao-Kun Zhang
69731-69745
Abstract  |  PDF  |  HTML  |  Order a Reprint

Let-7a inhibits migration, invasion and tumor growth by targeting AKT2 in papillary thyroid carcinoma

Let-7a inhibits migration, invasion and tumor growth by targeting AKT2 in papillary thyroid carcinoma

https://doi.org/10.18632/oncotarget.19261

Bin Zhou, Hailin Shan, Ying Su, Kai Xia, Runlong Zou,  and Qing Shao
69746-69755
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Application of in vivo imaging techniques to monitor therapeutic efficiency of PLX4720 in an experimental model of microsatellite instable colorectal cancer

Application of in vivo imaging techniques to monitor therapeutic efficiency of PLX4720 in an experimental model of microsatellite instable colorectal cancer

https://doi.org/10.18632/oncotarget.19263

Sarah Rohde, Tobias Lindner, Stefan Polei, Jan Stenzel, Luise Borufka, Sophie Achilles, Eric Hartmann, Falko Lange, Claudia Maletzki, Michael Linnebacher, Änne Glass, Sarah Marie Schwarzenböck, Jens Kurth, Alexander Hohn, Brigitte Vollmar, Bernd Joachim Krause,  and Robert Jaster
69756-69767
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Total flavones of abelmoschus manihot enhances angiogenic ability both in vitro and in vivo

Total flavones of abelmoschus manihot enhances angiogenic ability both in vitro and in vivo

https://doi.org/10.18632/oncotarget.19264

Lingyi Tang, Wu Pan, Guisong Zhu, Zhihui Liu, Dongling Lv,  and Meng Jiang
69768-69778
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Combination treatment with rucaparib (Rubraca) and MDM2 inhibitors, Nutlin-3 and RG7388, has synergistic and dose reduction potential in ovarian cancer

Combination treatment with rucaparib (Rubraca) and MDM2 inhibitors, Nutlin-3 and RG7388, has synergistic and dose reduction potential in ovarian cancer

https://doi.org/10.18632/oncotarget.19266

Maryam Zanjirband, Nicola Curtin, Richard J. Edmondson,  and John Lunec
69779-69796
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-34a modulates ionizing radiation-induced senescence in lung cancer cells

MiR-34a modulates ionizing radiation-induced senescence in lung cancer cells

https://doi.org/10.18632/oncotarget.19267

Xiaoyuan He, Aimin Yang, Daniel G. McDonald, Ellen C. Riemer, Kenneth N. Vanek, Bradley A. Schulte,  and Gavin Y. Wang
69797-69807
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CANcer-specific Evaluation System (CANES): a high-accuracy platform, for preclinical single/multi-biomarker discovery

CANcer-specific Evaluation System (CANES): a high-accuracy platform, for preclinical single/multi-biomarker discovery

https://doi.org/10.18632/oncotarget.19270

Min-Seok Kwon, Seungyoon Nam, Sungyoung Lee, Young Zoo Ahn, Hae Ryung Chang, Yon Hui Kim,  and Taesung Park
69808-69822
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The prognostic impacts of TEA domain (TEAD) transcription factor polymorphisms in Chinese hepatocellular carcinoma patients

The prognostic impacts of TEA domain (TEAD) transcription factor polymorphisms in Chinese hepatocellular carcinoma patients

https://doi.org/10.18632/oncotarget.19310

Haiyan Xia, Juan Wen, Weiyong Zhao, Dongying Gu, Zhibin Hu, Jinfei Chen,  and Zhi Xu
69823-69832
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Von Hippel-Lindau regulates interleukin-32β stability in ovarian cancer cells

Von Hippel-Lindau regulates interleukin-32β stability in ovarian cancer cells

https://doi.org/10.18632/oncotarget.19311

Hyo Jeong Yong, Jeong Su Park, Ae Lee Jeong, Sora Han, Sunyi Lee, Hye In Ka, Buyanravjkh Sumiyasuren, Hyun Jeong Joo, Su Jeong So, Ji Young Park, Do-Young Yoon, Jong Seok Lim, Myeong-Seok Lee, Hee Gu Lee,  and Young Yang
69833-69846
Abstract  |  PDF  |  HTML  |  Order a Reprint

NRF2-regulated metabolic gene signature as a prognostic biomarker in non-small cell lung cancer

NRF2-regulated metabolic gene signature as a prognostic biomarker in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.19349

Akhileshwar Namani, Qin Qin Cui, Yihe Wu, Hongyan Wang, Xiu Jun Wang,  and Xiuwen Tang
69847-69862
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

RNAi-mediated knockdown of Parp1 does not improve the development of female cloned mouse embryos

RNAi-mediated knockdown of Parp1 does not improve the development of female cloned mouse embryos

https://doi.org/10.18632/oncotarget.19418

Guang-Yu Bai, Si-Hang Song, Rui-Zhen Sun, Zi-Hui Zhang, Jingyu Li, Zhen-Dong Wang, Zhong-Hua Liu,  and Lei Lei
69863-69873
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Low dose of Bisphenol A enhance the susceptibility of thyroid carcinoma stimulated by DHPN and iodine excess in F344 rats

Low dose of Bisphenol A enhance the susceptibility of thyroid carcinoma stimulated by DHPN and iodine excess in F344 rats

https://doi.org/10.18632/oncotarget.19434

Jing Zhang, Xiaochen Zhang, Yanan Li, Zhenzhen Zhou, Chuanlong Wu, Zhiyan Liu, Lanxiang Hao, Shanshan Fan, Fang Jiang, Yan Xie,  and Ling Jiang
69874-69887
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Profiling cancer-associated genetic alterations and molecular classification of cancer in Korean gastric cancer patients

Profiling cancer-associated genetic alterations and molecular classification of cancer in Korean gastric cancer patients

https://doi.org/10.18632/oncotarget.19435

Yoonjung Kim, Mee-Yon Cho, Juwon Kim, Sung Nam Kim, Seoung Chul Oh,  and Kyung-A Lee
69888-69905
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Teriflunomide restores 5-azacytidine sensitivity via activation of pyrimidine salvage in 5-azacytidine-resistant leukemia cells

Teriflunomide restores 5-azacytidine sensitivity via activation of pyrimidine salvage in 5-azacytidine-resistant leukemia cells

https://doi.org/10.18632/oncotarget.19436

Satoshi Imanishi, Ryoko Takahashi, Seiichiro Katagiri, Chiaki Kobayashi, Tomohiro Umezu, Kazuma Ohyasiki,  and Junko H. Ohyashiki
69906-69915
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

SF3B1 mutation is a prognostic factor in chronic lymphocytic leukemia: a meta-analysis

SF3B1 mutation is a prognostic factor in chronic lymphocytic leukemia: a meta-analysis

https://doi.org/10.18632/oncotarget.19455

Zhenghao Zhang, Shu Chen, Shuang Chen, Gang Chen, Rui Zhang, Jinhua Li,  and Jianhua Qu
69916-69923
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Opposing roles of ICAT and Wnt/β-catenin signaling in NSC67657-induced monocytic differentiation

Opposing roles of ICAT and Wnt/β-catenin signaling in NSC67657-induced monocytic differentiation

https://doi.org/10.18632/oncotarget.19457

Weijia Wang, Yan Zhang, Yong Yuan, Runqiang Yuan, Youye Yang, Xiuming Zhang, Dongmei Wen, Fuda Huang,  and Jinshu Wang
69924-69933
Abstract  |  PDF  |  HTML  |  Order a Reprint

Differential expression of exosomal miRNAs between breast cancer patients with and without recurrence

Differential expression of exosomal miRNAs between breast cancer patients with and without recurrence

https://doi.org/10.18632/oncotarget.19482

Aiko Sueta, Yutaka Yamamoto, Mai Tomiguchi, Takashi Takeshita, Mutsuko Yamamoto-Ibusuki,  and Hirotaka Iwase
69934-69944
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

RGS19 upregulates Nm23-H1/2 metastasis suppressors by transcriptional activation via the cAMP/PKA/CREB pathway

RGS19 upregulates Nm23-H1/2 metastasis suppressors by transcriptional activation via the cAMP/PKA/CREB pathway

https://doi.org/10.18632/oncotarget.19509

Yuanjun Li, Jiaxing Song, Yao Tong, Sookja Kim Chung,  and Yung H. Wong
69945-69960
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic value of granulocyte colony-stimulating factor in patients with non-metastatic clear cell renal cell carcinoma

Prognostic value of granulocyte colony-stimulating factor in patients with non-metastatic clear cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.19540

Zheng Liu, Yu Zhu, Yiwei Wang, Qiang Fu, Hangcheng Fu, Zewei Wang, Junyu Zhang, Gaoxiang Li, Jiejie Xu,  and Bo Dai
69961-69971
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

In vitro and in vivo effects of suloctidil on growth and biofilm formation of the opportunistic fungus Candida albicans

In vitro and in vivo effects of suloctidil on growth and biofilm formation of the opportunistic fungus Candida albicans

https://doi.org/10.18632/oncotarget.19542

Beini Zeng, Jiachen Li, Yajie Wang, Pengxiang Chen, Xiaohong Wang, Jianfeng Cui, Lidong Liu, Xiaoyan Hu, Qian Cao, Ying Xiao, Junlu Dong, Yundong Sun,  and Yabin Zhou
69972-69982
Abstract  |  PDF  |  HTML  |  Order a Reprint

Linc-ROR induces epithelial-to-mesenchymal transition in ovarian cancer by increasing Wnt/β-catenin signaling

Linc-ROR induces epithelial-to-mesenchymal transition in ovarian cancer by increasing Wnt/β-catenin signaling

https://doi.org/10.18632/oncotarget.19545

Yanhui Lou, Huanhuan Jiang, Zhumei Cui, Lingzhi Wang, Xiangyu Wang,  and Tian Tian
69983-69994
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The diagnostic/prognostic potential and molecular functions of long non-coding RNAs in the exosomes derived from the bile of human cholangiocarcinoma

The diagnostic/prognostic potential and molecular functions of long non-coding RNAs in the exosomes derived from the bile of human cholangiocarcinoma

https://doi.org/10.18632/oncotarget.19547

Xianxiu Ge, Youli Wang, Junjie Nie, Quanpeng Li, Lingyu Tang, Xueting Deng, Fei Wang, Boming Xu, Xiaochao Wu, Xiuhua Zhang, Qiang You,  and Lin Miao
69995-70005
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Characterization of the subcellular localization of Epstein-Barr virus encoded proteins in live cells

Characterization of the subcellular localization of Epstein-Barr virus encoded proteins in live cells

https://doi.org/10.18632/oncotarget.19549

Mingsheng Cai, Zongmin Liao, Tao Chen, Ping Wang, Xingmei Zou, Yuanfang Wang, Zuo Xu, Si Jiang, Jinlu Huang, Daixiong Chen, Tao Peng, Gengde Hong,  and Meili Li
70006-70034
Abstract  |  PDF  |  HTML  |  Order a Reprint

Epigenetic silencing of TMEM176A promotes esophageal squamous cell cancer development

Epigenetic silencing of TMEM176A promotes esophageal squamous cell cancer development

https://doi.org/10.18632/oncotarget.19550

Ying Wang, You Zhang, James G. Herman, Enqiang Linghu,  and Mingzhou Guo
70035-70048
Abstract  |  PDF  |  HTML  |  Order a Reprint

Alpha-linolenic acid stabilizes HIF-1 α and downregulates FASN to promote mitochondrial apoptosis for mammary gland chemoprevention

Alpha-linolenic acid stabilizes HIF-1 α and downregulates FASN to promote mitochondrial apoptosis for mammary gland chemoprevention

https://doi.org/10.18632/oncotarget.19551

Subhadeep Roy, Atul Kumar Rawat, Shreesh Raj Sammi, Uma Devi, Manjari Singh, Swetlana Gautam, Rajnish Kumar Yadav, Jitendra Kumar Rawat, Lakhveer Singh, Mohd. Nazam Ansari, Abdulaziz S. Saeedan, Rakesh Pandey, Dinesh Kumar,  and Gaurav Kaithwas
70049-70071
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Longitudinal rotation: a new way to detect the cardiotoxicity of anthracycline-based chemotherapy in breast cancer patients

Longitudinal rotation: a new way to detect the cardiotoxicity of anthracycline-based chemotherapy in breast cancer patients

https://doi.org/10.18632/oncotarget.19585

Jun Huang, Zi-Ning Yan, Yi-Fei Rui, Dan Shen, Li Fan,  and Dong-Liang Chen
70072-70083
Abstract  |  PDF  |  HTML  |  Order a Reprint

The prognostic value of osteopontin in limited-stage small cell lung cancer patients and its mechanism

The prognostic value of osteopontin in limited-stage small cell lung cancer patients and its mechanism

https://doi.org/10.18632/oncotarget.19589

Fanglei Liu, Chunxue Bai,  and Zhongliang Guo
70084-70096
Abstract  |  PDF  |  HTML  |  Order a Reprint

The microRNA expression signature of pancreatic ductal adenocarcinoma by RNA sequencing: anti-tumour functions of the microRNA-216 cluster

The microRNA expression signature of pancreatic ductal adenocarcinoma by RNA sequencing: anti-tumour functions of the microRNA-216 cluster

https://doi.org/10.18632/oncotarget.19591

Keiichi Yonemori, Naohiko Seki, Tetsuya Idichi, Hiroshi Kurahara, Yusaku Osako, Keiichi Koshizuka, Takayuki Arai, Atsushi Okato, Yoshiaki Kita, Takaaki Arigami, Yuko Mataki, Yuko Kijima, Kosei Maemura,  and Shoji Natsugoe
70097-70115
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reactive oxygen species dependent phosphorylation of the liver kinase B1/AMP activated protein kinase/ acetyl-CoA carboxylase signaling is critically involved in apoptotic effect of lambertianic acid in hepatocellular carcinoma cells

Reactive oxygen species dependent phosphorylation of the liver kinase B1/AMP activated protein kinase/ acetyl-CoA carboxylase signaling is critically involved in apoptotic effect of lambertianic acid in hepatocellular carcinoma cells

https://doi.org/10.18632/oncotarget.19592

Arong Jeong, Ju-Ha Kim, Hyo Jung Lee,  and Sung Hoon Kim
70116-70129
Abstract  |  PDF  |  HTML  |  Order a Reprint

Physapubescin B inhibits tumorgenesis and circumvents taxol resistance of ovarian cancer cells through STAT3 signaling

Physapubescin B inhibits tumorgenesis and circumvents taxol resistance of ovarian cancer cells through STAT3 signaling

https://doi.org/10.18632/oncotarget.19593

Xiaofeng Zhao, Lu Huang, Wanwan Xu, Xiaoyan Chen, Yan Shen, Wenjie Zeng,  and Xiao Chen
70130-70141
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reversible regulation of ORC2 SUMOylation by PIAS4 and SENP2

Reversible regulation of ORC2 SUMOylation by PIAS4 and SENP2

https://doi.org/10.18632/oncotarget.19594

Ronghua Wang, Fangming Liu, Yongxu Zhao, Dan Wu, Lihan Chen, Edward T.H. Yeh,  and Chao Huang
70142-70155
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long non-coding RNA NEAT1 regulates epithelial membrane protein 2 expression to repress nasopharyngeal carcinoma migration and irradiation-resistance through miR-101-3p as a competing endogenous RNA mechanism

Long non-coding RNA NEAT1 regulates epithelial membrane protein 2 expression to repress nasopharyngeal carcinoma migration and irradiation-resistance through miR-101-3p as a competing endogenous RNA mechanism

https://doi.org/10.18632/oncotarget.19596

Yujia Wang, Chunting Wang, Can Chen, Fengbo Wu, Pengfei Shen, Peng Zhang, Gu He,  and Xiang Li
70156-70171
Abstract  |  PDF  |  HTML  |  Order a Reprint

Long non-coding RNA CARLo-5 promotes tumor progression in hepatocellular carcinoma via suppressing miR-200b expression

Long non-coding RNA CARLo-5 promotes tumor progression in hepatocellular carcinoma via suppressing miR-200b expression

https://doi.org/10.18632/oncotarget.19597

Chunqing Dou, Liyuan Sun, Xin Jin, Mingming Han, Bao Zhang, Xian Jiang, Jinyong Lv,  and Tao Li
70172-70182
Abstract  |  PDF  |  HTML  |  Order a Reprint

KIT performed as a driver gene candidate affecting the survival status of patients with stomach adenocarcinoma

KIT performed as a driver gene candidate affecting the survival status of patients with stomach adenocarcinoma

https://doi.org/10.18632/oncotarget.19598

Shengli Pan, Jin Tan, Yingying Deng, Ben-Hai Wan, Xiao-Yu Zhang,  and Bu-Gao Guan
70183-70191
Abstract  |  PDF  |  HTML  |  Order a Reprint

Sesquiterpene binding Gly-Leu-Ser/Lys-“co-adaptation pocket” to inhibit lung cancer cell epithelial–mesenchymal transition

Sesquiterpene binding Gly-Leu-Ser/Lys-“co-adaptation pocket” to inhibit lung cancer cell epithelial–mesenchymal transition

https://doi.org/10.18632/oncotarget.19599

Xiao-Yu Ai, Heng Zhang, Shao-Yan Gao, Yuan Qin, Wei-Long Zhong, Ju Gu, Meng Li, Kai-Liang Qiao, Qin Tian, Zhan-Hong Cui, Jia-Huan Yang, Zhun Bi, Ting Xiao, Shuang Chen, Hui-Juan Liu, Hong-Gang Zhou, Tao Sun,  and Cheng Yang
70192-70203
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Impact of marital status on renal cancer patient survival

Impact of marital status on renal cancer patient survival

https://doi.org/10.18632/oncotarget.19600

Hongzhi Wang, Lu Wang, Ildar Kabirov, Li Peng, Guang Chen, Yinhui Yang, Zamyatnin Andrey A,  and Wanhai Xu
70204-70213
Abstract  |  PDF  |  HTML  |  Order a Reprint

TGFβ induced factor homeobox 1 promotes colorectal cancer development through activating Wnt/β-catenin signaling

TGFβ induced factor homeobox 1 promotes colorectal cancer development through activating Wnt/β-catenin signaling

https://doi.org/10.18632/oncotarget.19603

Ji-Lian Wang, Zhen Qi, Ye-Hua Li, Hong-Mei Zhao, Ye-Guang Chen,  and Wei Fu
70214-70225
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Apparent diffusion coefficient histogram analysis can evaluate radiation-induced parotid damage and predict late xerostomia degree in nasopharyngeal carcinoma

Apparent diffusion coefficient histogram analysis can evaluate radiation-induced parotid damage and predict late xerostomia degree in nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.19602

Nan Zhou, Tingting Guo, Huanhuan Zheng, Xia Pan, Chen Chu, Xin Dou, Ming Li, Song Liu, Lijing Zhu, Baorui Liu, Weibo Chen, Jian He, Jing Yan, Zhengyang Zhou,  and Xiaofeng Yang
70226-70238
Abstract  |  PDF  |  HTML  |  Order a Reprint

Alisol B 23-acetate induces autophagic-dependent apoptosis in human colon cancer cells via ROS generation and JNK activation

Alisol B 23-acetate induces autophagic-dependent apoptosis in human colon cancer cells via ROS generation and JNK activation

https://doi.org/10.18632/oncotarget.19605

Yueliang Zhao, Edmund T.S. Li,  and Mingfu Wang
70239-70249
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A new donors’ CYP3A5 and recipients’ CYP3A4 cluster predicting tacrolimus disposition, and new-onset hypertension in Chinese liver transplant patients

A new donors’ CYP3A5 and recipients’ CYP3A4 cluster predicting tacrolimus disposition, and new-onset hypertension in Chinese liver transplant patients

https://doi.org/10.18632/oncotarget.19606

Yuan Liu, Tao Zhang, Xiaoqing Zhang, Ling Ye, Haitao Gu, Lin Zhong, Hongcheng Sun, Chenlong Song, Zhihai Peng,  and Junwei Fan
70250-70261
Abstract  |  PDF  |  HTML  |  Order a Reprint

The clinical significance of HPIP and the associated prognosis in cervical cancer

The clinical significance of HPIP and the associated prognosis in cervical cancer

https://doi.org/10.18632/oncotarget.19607

Fanling Meng, Haixia Liu, Shuang Liu,  and Rong Ma
70262-70270
Abstract  |  PDF  |  HTML  |  Order a Reprint

Identification of core genes and outcome in gastric cancer using bioinformatics analysis

Identification of core genes and outcome in gastric cancer using bioinformatics analysis

https://doi.org/10.18632/oncotarget.20082

Chenhua Sun, Qi Yuan, Dongdong Wu, Xiaohu Meng,  and Baolin Wang
70271-70280
Abstract  |  PDF  |  HTML  |  Order a Reprint

SSeCKS/AKAP12 scaffolding functions suppress B16F10-induced peritoneal metastasis by attenuating CXCL9/10 secretion by resident fibroblasts

SSeCKS/AKAP12 scaffolding functions suppress B16F10-induced peritoneal metastasis by attenuating CXCL9/10 secretion by resident fibroblasts

https://doi.org/10.18632/oncotarget.20092

Masashi Muramatsu, Lingqiu Gao, Jennifer Peresie, Benjamin Balderman, Shin Akakura,  and Irwin H. Gelman
70281-70298
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Standardized tumor volume: an independent prognostic factor in advanced nasopharyngeal carcinoma

Standardized tumor volume: an independent prognostic factor in advanced nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.20313

Ting Liu, Jun Lv,  and Yutao Qin
70299-70309
Abstract  |  PDF  |  HTML  |  Order a Reprint

IL-23R and IL-17A polymorphisms correlate with susceptibility of ankylosing spondylitis in a Southwest Chinese population

IL-23R and IL-17A polymorphisms correlate with susceptibility of ankylosing spondylitis in a Southwest Chinese population

https://doi.org/10.18632/oncotarget.20319

Bin Yang, Yuanwei Xu, Xinle Liu, Zhuochun Huang,  and Lanlan Wang
70310-70316
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Effective antitumor peptide vaccines can induce severe autoimmune pathology

Effective antitumor peptide vaccines can induce severe autoimmune pathology

https://doi.org/10.18632/oncotarget.19688

Hussein Sultan, Jimena Trillo-Tinoco, Paulo Rodriguez,  and Esteban Celis
70317-70331
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Omeprazole promotes carcinogenesis of fore-stomach in mice with co-stimulation of nitrosamine

Omeprazole promotes carcinogenesis of fore-stomach in mice with co-stimulation of nitrosamine

https://doi.org/10.18632/oncotarget.19696

Lei Huang, Dong-Jiang Qi, Wei He,  and A-Man Xu
70332-70344
Abstract  |  PDF  |  HTML  |  Order a Reprint

Mutational analysis of a Chinese family with oculocutaneous albinism type 2

Mutational analysis of a Chinese family with oculocutaneous albinism type 2

https://doi.org/10.18632/oncotarget.19697

Xiong Wang, Yaowu Zhu, Na Shen, Jing Peng, Chunyu Wang, Haiyi Liu,  and Yanjun Lu
70345-70355
Abstract  |  PDF  |  HTML  |  Order a Reprint

High-dose atorvastatin reduces the risk of cardiovascular events in patients with percutaneous coronary intervention

High-dose atorvastatin reduces the risk of cardiovascular events in patients with percutaneous coronary intervention

https://doi.org/10.18632/oncotarget.19701

Changqing Lu, Helei Jia,  and Zhentao Wang
70356-70365
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A prospective study of serum metabolites and glioma risk

A prospective study of serum metabolites and glioma risk

https://doi.org/10.18632/oncotarget.19705

Jiaqi Huang, Stephanie J. Weinstein, Cari M. Kitahara, Edward D. Karoly, Joshua N. Sampson,  and Demetrius Albanes
70366-70377
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association between the MVK and MMAB polymorphisms and serum lipid levels

Association between the MVK and MMAB polymorphisms and serum lipid levels

https://doi.org/10.18632/oncotarget.19707

Liu Miao, Rui-Xing Yin, Shang-Ling Pan, Shuo Yang, De-Zhai Yang,  and Wei-Xiong Lin
70378-70393
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The protective effects of polysaccharide of Atractylodes macrocephala Koidz (PAMK) on the chicken spleen under heat stress via antagonizing apoptosis and restoring the immune function

The protective effects of polysaccharide of Atractylodes macrocephala Koidz (PAMK) on the chicken spleen under heat stress via antagonizing apoptosis and restoring the immune function

https://doi.org/10.18632/oncotarget.19709

Danning Xu, Bingxin Li, Nan Cao, Wanyan Li, Yunbo Tian,  and Yunmao Huang
70394-70405
Abstract  |  PDF  |  HTML  |  Order a Reprint

Acrolein induces mtDNA damages, mitochondrial fission and mitophagy in human lung cells

Acrolein induces mtDNA damages, mitochondrial fission and mitophagy in human lung cells

https://doi.org/10.18632/oncotarget.19710

Hsiang-Tsui Wang, Jing-Heng Lin, Chun-Hsiang Yang, Chun-Hao Haung, Ching-Wen Weng, Anya Maan-Yuh Lin, Yu-Li Lo, Wei-Shen Chen,  and Moon-Shong Tang
70406-70421
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

GMI ablates cancer stemness and cisplatin resistance in oral carcinomas stem cells through IL-6/Stat3 signaling inhibition

GMI ablates cancer stemness and cisplatin resistance in oral carcinomas stem cells through IL-6/Stat3 signaling inhibition

https://doi.org/10.18632/oncotarget.19711

Tung Yuan Wang, Cheng-Chia Yu, Pei-Ling Hsieh, Yi-Wen Liao, Chuan-Hang Yu,  and Ming-Yung Chou
70422-70430
Abstract  |  PDF  |  HTML  |  Order a Reprint

Natural killer cell activity for IFN-gamma production as a supportive diagnostic marker for gastric cancer

Natural killer cell activity for IFN-gamma production as a supportive diagnostic marker for gastric cancer

https://doi.org/10.18632/oncotarget.19712

Jongmi Lee, Ki Hyun Park, Ji Hyeong Ryu, Hyun Jin Bae, Aeran Choi, Hyeyoung Lee, Jihyang Lim, Kyungja Han, Cho Hyun Park, Eun Sun Jung,  and Eun-Jee Oh
70431-70440
Abstract  |  PDF  |  HTML  |  Order a Reprint

FOXK1 facilitates cell proliferation through regulating the expression of p21, and promotes metastasis in ovarian cancer

FOXK1 facilitates cell proliferation through regulating the expression of p21, and promotes metastasis in ovarian cancer

https://doi.org/10.18632/oncotarget.19713

Li Li, Miao Gong, Yu Zhao, Xiujun Zhao,  and Quanhai Li
70441-70451
Abstract  |  PDF  |  HTML  |  Order a Reprint

Proapoptotic function of deubiquitinase DUSP31 in Drosophila

Proapoptotic function of deubiquitinase DUSP31 in Drosophila

https://doi.org/10.18632/oncotarget.19715

Sergey A. Sinenko
70452-70462
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The density of mast cells c-Kit+ and tryptase+ correlates with each other and with angiogenesis in pancreatic cancer patients

The density of mast cells c-Kit+ and tryptase+ correlates with each other and with angiogenesis in pancreatic cancer patients

https://doi.org/10.18632/oncotarget.19716

Michele Ammendola, Cosmo Damiano Gadaleta, Adam Enver Frampton, Tullio Piardi, Riccardo Memeo, Valeria Zuccalà, Maria Luposella, Rosa Patruno, Nicola Zizzo, Pietro Gadaleta, Patrick Pessaux, Rosario Sacco, Giuseppe Sammarco,  and Girolamo Ranieri
70463-70471
Abstract  |  PDF  |  HTML  |  Order a Reprint

A comprehensive study of circulating tumour cells at the moment of prostate cancer diagnosis: biological and clinical implications of EGFR, AR and SNPs

A comprehensive study of circulating tumour cells at the moment of prostate cancer diagnosis: biological and clinical implications of EGFR, AR and SNPs

https://doi.org/10.18632/oncotarget.19718

Ignacio Puche-Sanz, María J. Alvarez-Cubero, Manrique Pascual-Geler, Alba Rodríguez-Martínez, Miguel Delgado-Rodríguez, José L. García-Puche, José Expósito, Inmaculada Robles-Fernández, Carmen Entrala-Bernal, José A. Lorente, José M. Cózar-Olmo,  and María J. Serrano
70472-70480
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reverse phase protein array identification of triple-negative breast cancer subtypes and comparison with mRNA molecular subtypes

Reverse phase protein array identification of triple-negative breast cancer subtypes and comparison with mRNA molecular subtypes

https://doi.org/10.18632/oncotarget.19719

Hiroko Masuda, Yuan Qi, Shuying Liu, Naoki Hayashi, Takahiro Kogawa, Gabriel N. Hortobagyi, Debu Tripathy,  and Naoto T. Ueno
70481-70495
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cytochalasin B-induced membrane vesicles convey angiogenic activity of parental cells

Cytochalasin B-induced membrane vesicles convey angiogenic activity of parental cells

https://doi.org/10.18632/oncotarget.19723

Marina O. Gomzikova, Margarita N. Zhuravleva, Regina R. Miftakhova, Svetlana S. Arkhipova, Vladimir G. Evtugin, Svetlana F. Khaiboullina, Andrey P. Kiyasov, Jenny L. Persson, Nigel P. Mongan, Richard G. Pestell,  and Albert A. Rizvanov
70496-70507
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Overexpression of COL3A1 confers a poor prognosis in human bladder cancer identified by co-expression analysis

Overexpression of COL3A1 confers a poor prognosis in human bladder cancer identified by co-expression analysis

https://doi.org/10.18632/oncotarget.19733

Lushun Yuan, Bo Shu, Liang Chen, Kaiyu Qian, Yongzhi Wang, Guofeng Qian, Yuan Zhu, Xinyue Cao, Conghua Xie, Yu Xiao,  and Xinghuan Wang
70508-70520
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Exostosin 1 regulates cancer cell stemness in doxorubicin-resistant breast cancer cells

Exostosin 1 regulates cancer cell stemness in doxorubicin-resistant breast cancer cells

https://doi.org/10.18632/oncotarget.19737

Sarala Manandhar, Chang-Gu Kim, Sun-Hee Lee, Soo Hyun Kang, Nikita Basnet,  and You Mie Lee
70521-70537
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TFCP2 activates beta-catenin/TCF signaling in the progression of pancreatic cancer

TFCP2 activates beta-catenin/TCF signaling in the progression of pancreatic cancer

https://doi.org/10.18632/oncotarget.19741

Dai Yuedi, Cai Yuankun, Zhao Jiaying, Liu Han, Wang Yueqi, Liu Houbao,  and Zhang Dexiang
70538-70549
Abstract  |  PDF  |  HTML  |  Order a Reprint

MiR-377 promotes white adipose tissue inflammation and decreases insulin sensitivity in obesity via suppression of sirtuin-1 (SIRT1)

MiR-377 promotes white adipose tissue inflammation and decreases insulin sensitivity in obesity via suppression of sirtuin-1 (SIRT1)

https://doi.org/10.18632/oncotarget.19742

Jie Peng, Yinghui Wu, Zhao Deng, Yuanfei Zhou, Tongxing Song, Yang Yang, Xiaming Zhang, Tao Xu, Mao Xia, Anle Cai, Zuhong Liu,  and Jian Peng
70550-70563
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

2L-PCA: a two-level principal component analyzer for quantitative drug design and its applications

2L-PCA: a two-level principal component analyzer for quantitative drug design and its applications

https://doi.org/10.18632/oncotarget.19757

Qi-Shi Du, Shu-Qing Wang, Neng-Zhong Xie, Qing-Yan Wang, Ri-Bo Huang,  and Kuo-Chen Chou
70564-70578
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dysregulated expression of homeobox family genes may influence survival outcomes of patients with epithelial ovarian cancer: analysis of data from The Cancer Genome Atlas

Dysregulated expression of homeobox family genes may influence survival outcomes of patients with epithelial ovarian cancer: analysis of data from The Cancer Genome Atlas

https://doi.org/10.18632/oncotarget.19771

Kyung Jin Eoh, Hee Jung Kim, Jung-Yun Lee, Eun Ji Nam, Sunghoon Kim, Sang Wun Kim,  and Young Tae Kim
70579-70585
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Validation of the 8th edition of the UICC/AJCC staging system for nasopharyngeal carcinoma treated with intensity-modulated radiotherapy

Validation of the 8th edition of the UICC/AJCC staging system for nasopharyngeal carcinoma treated with intensity-modulated radiotherapy

https://doi.org/10.18632/oncotarget.19829

Min Kang, Pingting Zhou, Guisheng Li, Haolin Yan, Guosheng Feng, Meilian Liu, Jinxian Zhu,  and Rensheng Wang
70586-70594
Abstract  |  PDF  |  HTML  |  Order a Reprint

Calyxin Y sensitizes cisplatin-sensitive and resistant hepatocellular carcinoma cells to cisplatin through apoptotic and autophagic cell death via SCF βTrCP-mediated eEF2K degradation

Calyxin Y sensitizes cisplatin-sensitive and resistant hepatocellular carcinoma cells to cisplatin through apoptotic and autophagic cell death via SCF βTrCP-mediated eEF2K degradation

https://doi.org/10.18632/oncotarget.19883

Chao Zhang, Jian-Li Lei, Hao Zhang, Yuan-Zheng Xia, Pei Yu, Lei Yang,  and Ling-Yi Kong
70595-70616
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The hyaluronan-mediated motility receptor RHAMM promotes growth, invasiveness and dissemination of colorectal cancer

The hyaluronan-mediated motility receptor RHAMM promotes growth, invasiveness and dissemination of colorectal cancer

https://doi.org/10.18632/oncotarget.19904

Valentina Mele, Lena Sokol, Viktor Hendrik Kölzer, Dennis Pfaff, Manuele Giuseppe Muraro, Irene Keller, Zahnd Stefan, Irene Centeno, Luigi Maria Terracciano, Heather Dawson, Inti Zlobec, Giandomenica Iezzi,  and Alessandro Lugli
70617-70629
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

LncSHRG promotes hepatocellular carcinoma progression by activating HES6

LncSHRG promotes hepatocellular carcinoma progression by activating HES6

https://doi.org/10.18632/oncotarget.19906

Ying-Chen Xu, Chao-Jie Liang, Dong-Xin Zhang, Guan-Qun Li, Xia Gao, Jian-Zhu Fu, Feng Xia, Jia-Jun Ji, Li-Jun Zhang, Guang-Ming Li,  and Ji-Xiang Wu
70630-70641
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The lncRNA HOXA11-AS functions as a competing endogenous RNA to regulate PADI2 expression by sponging miR-125a-5p in liver metastasis of colorectal cancer

The lncRNA HOXA11-AS functions as a competing endogenous RNA to regulate PADI2 expression by sponging miR-125a-5p in liver metastasis of colorectal cancer

https://doi.org/10.18632/oncotarget.19956

Dong Chen, Qiang Sun, Lufei Zhang, Xiaohu Zhou, Xiaofei Cheng, Dongkai Zhou, Feng Ye, Jianjiang Lin,  and Weilin Wang
70642-70652
Abstract  |  PDF  |  HTML  |  Order a Reprint

Fibronectin in cell adhesion and migration via N-glycosylation

Fibronectin in cell adhesion and migration via N-glycosylation

https://doi.org/10.18632/oncotarget.19969

Cheng-Te Hsiao, Hung-Wei Cheng, Chi-Ming Huang, Hao-Ru Li, Meng-Hsin Ou, Jie-Rong Huang, Kay-Hooi Khoo, Helen Wenshin Yu, Yin-Quan Chen, Yang-Kao Wang, Arthur Chiou,  and Jean-Cheng Kuo
70653-70668
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-27b inhibition promotes Nrf2/ARE pathway activation and alleviates intracerebral hemorrhage-induced brain injury

MicroRNA-27b inhibition promotes Nrf2/ARE pathway activation and alleviates intracerebral hemorrhage-induced brain injury

https://doi.org/10.18632/oncotarget.19974

Wenzhe Xu, Feng Li, Zhiguo Liu, Zhenkuan Xu, Bin Sun, Jingwei Cao,  and Yuguang Liu
70669-70684
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TMEM17 depresses invasion and metastasis in lung cancer cells via ERK signaling pathway

TMEM17 depresses invasion and metastasis in lung cancer cells via ERK signaling pathway

https://doi.org/10.18632/oncotarget.19977

Xiupeng Zhang, Yong Zhang, Yuan Miao, Haijing Zhou, Guiyang Jiang,  and Enhua Wang
70685-70694
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Non-alcoholic steatohepatitis-related liver tumorigenesis is suppressed in mice lacking hepatic retinoid storage

Non-alcoholic steatohepatitis-related liver tumorigenesis is suppressed in mice lacking hepatic retinoid storage

https://doi.org/10.18632/oncotarget.19978

Takayasu Ideta, Yohei Shirakami, Masaya Ohnishi, Akinori Maruta, Koki Obara, Tsuneyuki Miyazaki, Takahiro Kochi, Hiroyasu Sakai, Hiroyuki Tomita, Takuji Tanaka, William S. Blaner,  and Masahito Shimizu
70695-70706
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Adipose-derived mesenchymal stem cells employed exosomes to attenuate AKI-CKD transition through tubular epithelial cell dependent Sox9 activation

Adipose-derived mesenchymal stem cells employed exosomes to attenuate AKI-CKD transition through tubular epithelial cell dependent Sox9 activation

https://doi.org/10.18632/oncotarget.19979

Fengming Zhu, Octavia L.S. Chong Lee Shin, Guangchang Pei, Zhizhi Hu, Juan Yang, Han Zhu, Meng Wang, Jingyi Mou, Jie Sun, Yuxi Wang, Qian Yang, Zhi Zhao, Huzi Xu, Hui Gao, Weiqi Yao, Xiao Luo, Wenhui Liao, Gang Xu, Rui Zeng,  and Ying Yao
70707-70726
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Applicability of graded prognostic assessment of lung cancer using molecular markers to lung adenocarcinoma patients with brain metastases

Applicability of graded prognostic assessment of lung cancer using molecular markers to lung adenocarcinoma patients with brain metastases

https://doi.org/10.18632/oncotarget.19980

Hongwei Li, Jianhong Lian, Songyan Han, Weili Wang, Haixia Jia, Jianzhong Cao, Xiaqin Zhang, Xin Song, Sufang Jia, Jiwei Ren, Weihua Yang, Yanfeng Xi,  and Shengmin Lan
70727-70735
Abstract  |  PDF  |  HTML  |  Order a Reprint

The activation of SRC family kinases and focal adhesion kinase with the loss of the amplified, mutated EGFR gene contributes to the resistance to afatinib, erlotinib and osimertinib in human lung cancer cells

The activation of SRC family kinases and focal adhesion kinase with the loss of the amplified, mutated EGFR gene contributes to the resistance to afatinib, erlotinib and osimertinib in human lung cancer cells

https://doi.org/10.18632/oncotarget.19982

Yuichi Murakami, Kahori Sonoda, Hideyuki Abe, Kosuke Watari, Daiki Kusakabe, Koichi Azuma, Akihiko Kawahara, Jun Akiba, Chitose Oneyama, Jonathan A. Pachter, Kazuko Sakai, Kazuto Nishio, Michihiko Kuwano,  and Mayumi Ono
70736-70751
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pharmacokinetics and drug-drug interaction between enalapril, enalaprilat and felodipine extended release (ER) in healthy subjects

Pharmacokinetics and drug-drug interaction between enalapril, enalaprilat and felodipine extended release (ER) in healthy subjects

https://doi.org/10.18632/oncotarget.19984

Dai Li, Sumei Xu, Yulu Wang, Dan Li, Xiaomin Li, Jing Pan,  and Pingsheng Xu
70752-70760
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNA-542-3p inhibits oral squamous cell carcinoma progression by inhibiting ILK/TGF-β1/Smad2/3 signaling

MicroRNA-542-3p inhibits oral squamous cell carcinoma progression by inhibiting ILK/TGF-β1/Smad2/3 signaling

https://doi.org/10.18632/oncotarget.19986

Bin Qiao, Jing-Hua Cai, Alfred King-Yin Lam,  and Bao-Xia He
70761-70776
Abstract  |  PDF  |  HTML  |  Order a Reprint

Unanticipated prognosis of differential thyroid cancer patients with T0 stage: analysis of the SEER database 2004-2013

Unanticipated prognosis of differential thyroid cancer patients with T0 stage: analysis of the SEER database 2004-2013

https://doi.org/10.18632/oncotarget.19988

Chunping Liu, Jie Ming, Wen Zeng, Shuntao Wang, Yiquan Xiong, Qiuyang Zhao, Xingjie Yin, Zeming Liu,  and Tao Huang
70777-70787
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical efficacy of endostar combined with chemotherapy in the treatment of peritoneal carcinomatosis in gastric cancer: results from a retrospective study

Clinical efficacy of endostar combined with chemotherapy in the treatment of peritoneal carcinomatosis in gastric cancer: results from a retrospective study

https://doi.org/10.18632/oncotarget.19989

Jing Yao, Li Fan, Chunfen Peng, Ai Huang, Tao Liu, Zhenyu Lin, Qin Yang, Tao Zhang,  and Hong Ma
70788-70797
Abstract  |  PDF  |  HTML  |  Order a Reprint

Epigenetic regulation of interleukin-8 expression by class I HDAC and CBP in ovarian cancer cells

Epigenetic regulation of interleukin-8 expression by class I HDAC and CBP in ovarian cancer cells

https://doi.org/10.18632/oncotarget.19990

Himavanth R. Gatla, Yue Zou, Mohammad M. Uddin,  and Ivana Vancurova
70798-70810
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Interaction among CYP2C8, GPIIIa and P2Y12 variants increase susceptibility to ischemic stroke in Chinese population

Interaction among CYP2C8, GPIIIa and P2Y12 variants increase susceptibility to ischemic stroke in Chinese population

https://doi.org/10.18632/oncotarget.19991

Xingyang Yi, Jing Lin, Yanfen Wang, Ju Zhou,  and Qiang Zhou
70811-70820
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNA-466 with tumor markers for cervical cancer screening

MicroRNA-466 with tumor markers for cervical cancer screening

https://doi.org/10.18632/oncotarget.19992

Li-Li Zhou, Yong Shen, Jiao-Mei Gong, Ping Sun,  and Jia-He Sheng
70821-70827
Abstract  |  PDF  |  HTML  |  Order a Reprint

Histone deacetylase inhibitor thailandepsin-A activates Notch signaling and suppresses neuroendocrine cancer cell growth in vivo

Histone deacetylase inhibitor thailandepsin-A activates Notch signaling and suppresses neuroendocrine cancer cell growth in vivo

https://doi.org/10.18632/oncotarget.19993

Samuel Jang, Andrew Janssen, Zviadi Aburjania, Matthew B. Robers, April Harrison, Ajitha Dammalapati, Yi-Qiang Cheng, Herbert Chen,  and Renata Jaskula-Sztul
70828-70840
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic and predictive value of metastatic lymph node ratio in stage III gastric cancer after D2 nodal dissection

Prognostic and predictive value of metastatic lymph node ratio in stage III gastric cancer after D2 nodal dissection

https://doi.org/10.18632/oncotarget.19998

Yinbo Chen, Cong Li, Yian Du, Qi Xu, Jieer Ying,  and Cong Luo
70841-70846
Abstract  |  PDF  |  HTML  |  Order a Reprint

Toll-like receptor 3 pathway restricts Marek’s disease virus infection

Toll-like receptor 3 pathway restricts Marek’s disease virus infection

https://doi.org/10.18632/oncotarget.20003

Haitao Zou, Ruixue Su, Jing Ruan, Hongxia Shao, Kun Qian, Jianqiang Ye,  and Aijian Qin
70847-70853
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Different effection of p.1125Val>Ala and rs11954856 in APC on Wnt signaling pathway

Different effection of p.1125Val>Ala and rs11954856 in APC on Wnt signaling pathway

https://doi.org/10.18632/oncotarget.20106

Fei-Feng Li, Zhi-Xun Zhao, Peng Yan, Song Wang, Zheng Liu, Qiong Zhang, Xiao-Ning Zhang, Chang-Hao Sun, Xi-Shan Wang, Gui-Yu Wang,  and Shu-Lin Liu
70854-70864
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic and predictive value of serum carcinoembryonic antigen levels in advanced non-small cell lung cancer patients with epidermal growth factor receptor sensitive mutations and receiving tyrosine kinase inhibitors

Prognostic and predictive value of serum carcinoembryonic antigen levels in advanced non-small cell lung cancer patients with epidermal growth factor receptor sensitive mutations and receiving tyrosine kinase inhibitors

https://doi.org/10.18632/oncotarget.20145

Xin Min Zhao, Jing Zhao, Kai Lin Xing, Si Sun, Zhi Guo Luo, Hui Jie Wang, Jia Lei Wang, Jian Hua Chang,  and Xiang Hua Wu
70865-70873
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prognostic role of pretreatment platelet to lymphocyte ratio in urologic cancer

Prognostic role of pretreatment platelet to lymphocyte ratio in urologic cancer

https://doi.org/10.18632/oncotarget.20147

Jianfeng Wang, Yang Liu, Naiwen Zhang, Xuejie Li, Peng Xin, Jianbin Bi,  and Chuize Kong
70874-70882
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Differentiation between high- and low-grade urothelial carcinomas using contrast enhanced ultrasound

Differentiation between high- and low-grade urothelial carcinomas using contrast enhanced ultrasound

https://doi.org/10.18632/oncotarget.20151

Qiuyang Li, Jie Tang, Enhui He, Yanmi Li, Yun Zhou,  and Baojun Wang
70883-70889
Abstract  |  PDF  |  HTML  |  Order a Reprint

MiR-196a2 and lung cancer in Chinese non-smoking females: a genetic association study and expression analysis

MiR-196a2 and lung cancer in Chinese non-smoking females: a genetic association study and expression analysis

https://doi.org/10.18632/oncotarget.20174

Zhihua Yin, Zhigang Cui, Yangwu Ren, Lingzi Xia, Hang Li,  and Baosen Zhou
70890-70898
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A GLO10 score for the prediction of prognosis in high grade gliomas

A GLO10 score for the prediction of prognosis in high grade gliomas

https://doi.org/10.18632/oncotarget.20195

Feng Chen, Peng Peng, Yi Zhou, Zhen-Yu Yang, Hai-Quan Zhang, Xiang-Sheng Ao, Da-Quan Zhou,  and Chun-Xiang Xiang
70899-70906
Abstract  |  PDF  |  HTML  |  Order a Reprint

Survival outcomes based on systemic agent used concurrently with radiation in human-papillomavirus associated oropharyngeal cancer

Survival outcomes based on systemic agent used concurrently with radiation in human-papillomavirus associated oropharyngeal cancer

https://doi.org/10.18632/oncotarget.20197

Vikas Mehta, Tara Moore-Medlin, Jose M. Flores, Xiaohui Ma, Oleksandr Ekshyyan,  and Cherie-Ann O. Nathan
70907-70915
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Characterization of CADD522, a small molecule that inhibits RUNX2-DNA binding and exhibits antitumor activity

Characterization of CADD522, a small molecule that inhibits RUNX2-DNA binding and exhibits antitumor activity

https://doi.org/10.18632/oncotarget.20200

Myoung Sook Kim, Ramkishore Gernapudi, Eun Yong Choi, Rena G. Lapidus,  and Antonino Passaniti
70916-70940
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Detection of active proteasome structures in brain extracts: proteasome features of August rat brain with violations in monoamine metabolism

Detection of active proteasome structures in brain extracts: proteasome features of August rat brain with violations in monoamine metabolism

https://doi.org/10.18632/oncotarget.20208

Pavel A. Erokhov, Yulia V. Lyupina, Alexandra S. Radchenko, Anna A. Kolacheva, Yulia O. Nikishina,  and Natalia P. Sharova
70941-70957
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Evidence for the association of chromatin and microRNA regulation in the human genome

Evidence for the association of chromatin and microRNA regulation in the human genome

https://doi.org/10.18632/oncotarget.20214

Bang-Bao Tao, Xi-Qiang Liu, Wenhao Zhang, Shu Li, Dong Dong, Mang Xiao,  and Jun Zhong
70958-70966
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Transcriptional downregulation of microRNA-19a by ROS production and NF-κB deactivation governs resistance to oxidative stress-initiated apoptosis

Transcriptional downregulation of microRNA-19a by ROS production and NF-κB deactivation governs resistance to oxidative stress-initiated apoptosis

https://doi.org/10.18632/oncotarget.20235

Jun Hong, Ying Wang, Bang-Chuan Hu, Liang Xu, Jing-Quan Liu, Min-Hua Chen, Jin-Zhu Wang, Fang Han, Yang Zheng, Xu Chen, Qian Li, Xiang-Hong Yang, Ren-Hua Sun,  and Shi-Jing Mo
70967-70981
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Comprehensive immune transcriptomic analysis in bladder cancer reveals subtype specific immune gene expression patterns of prognostic relevance

Comprehensive immune transcriptomic analysis in bladder cancer reveals subtype specific immune gene expression patterns of prognostic relevance

https://doi.org/10.18632/oncotarget.20237

Runhan Ren, Kathrin Tyryshkin, Charles H. Graham, Madhuri Koti,  and D. Robert Siemens
70982-71001
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tumor-infiltrating B cells producing antitumor active immunoglobulins in resected HCC prolong patient survival

Tumor-infiltrating B cells producing antitumor active immunoglobulins in resected HCC prolong patient survival

https://doi.org/10.18632/oncotarget.20238

Stefan M. Brunner, Timo Itzel, Christoph Rubner, Rebecca Kesselring, Eva Griesshammer, Matthias Evert, Andreas Teufel, Hans J. Schlitt,  and Stefan Fichtner-Feigl
71002-71011
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Aberrant expression of OATP1B3 in colorectal cancer liver metastases and its clinical implication on gadoxetic acid-enhanced MRI

Aberrant expression of OATP1B3 in colorectal cancer liver metastases and its clinical implication on gadoxetic acid-enhanced MRI

https://doi.org/10.18632/oncotarget.20295

Seung Hyun Park, Honsoul Kim, Eun Kyung Kim, Hogeun Kim, Dong Kyu Choi, Yong Eun Chung, Myeong-Jin Kim,  and Jin-Young Choi
71012-71023
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

NOGO-B promotes EMT in lung fibrosis via MMP14 mediates free TGF-beta1 formation

NOGO-B promotes EMT in lung fibrosis via MMP14 mediates free TGF-beta1 formation

https://doi.org/10.18632/oncotarget.20297

Ye Xiong, Jing Zhang, Lingzhi Shi, Yunye Ning, Ying Zhu, Si Chen, Meng Yang, Jingyu Chen, Guo-Wu Zhou,  and Qiang Li
71024-71037
Abstract  |  PDF  |  HTML  |  Order a Reprint

Geraniol alleviates LPS-induced acute lung injury in mice via inhibiting inflammation and apoptosis

Geraniol alleviates LPS-induced acute lung injury in mice via inhibiting inflammation and apoptosis

https://doi.org/10.18632/oncotarget.20298

Kangfeng Jiang, Tao Zhang, Nannan Yin, Xiaofei Ma, Gan Zhao, Haichong Wu, Changwei Qiu,  and Ganzhen Deng
71038-71053
Abstract  |  PDF  |  HTML  |  Order a Reprint

Role of the CYP3A4-mediated 11,12-epoxyeicosatrienoic acid pathway in the development of tamoxifen-resistant breast cancer

Role of the CYP3A4-mediated 11,12-epoxyeicosatrienoic acid pathway in the development of tamoxifen-resistant breast cancer

https://doi.org/10.18632/oncotarget.20329

Nguyen Thi Thuy Phuong, Ji Won Kim, Jung-Ae Kim, Jang Su Jeon, Ji-Yoon Lee, Wen Jun Xu, Jin Won Yang, Sang Kyum Kim,  and Keon Wook Kang
71054-71069
Abstract  |  PDF  |  HTML  |  Order a Reprint

An integrated multigene expression panel to predict long-term survival after curative hepatectomy in patients with hepatocellular carcinoma

An integrated multigene expression panel to predict long-term survival after curative hepatectomy in patients with hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.20369

Mitsuro Kanda, Kenta Murotani, Hiroyuki Sugimoto, Takashi Miwa, Shinichi Umeda, Masaya Suenaga, Masamichi Hayashi, Norifumi Hattori, Chie Tanaka, Daisuke Kobayashi, Suguru Yamada, Michitaka Fujiwara,  and Yasuhiro Kodera
71070-71079
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-141-3p promotes glioma cell growth and temozolomide resistance by directly targeting p53

MicroRNA-141-3p promotes glioma cell growth and temozolomide resistance by directly targeting p53

https://doi.org/10.18632/oncotarget.20528

Xu Zhou, Weining Wu, Ailiang Zeng, Er Nie, Xin Jin, Tianfu Yu, Tongle Zhi, Kuan Jiang, Yingyi Wang, Junxia Zhang,  and Yongping You
71080-71094
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Differential diagnosis of hemangiomas from spinal osteolytic metastases using 3.0 T MRI: comparison of T1-weighted imaging, chemical-shift imaging, diffusion-weighted and contrast-enhanced imaging

Differential diagnosis of hemangiomas from spinal osteolytic metastases using 3.0 T MRI: comparison of T1-weighted imaging, chemical-shift imaging, diffusion-weighted and contrast-enhanced imaging

https://doi.org/10.18632/oncotarget.20533

Yan-Jie Shi, Xiao-Ting Li, Xiao-Yan Zhang, Yu-Liang Liu, Lei Tang,  and Ying-Shi Sun
71095-71104
Abstract  |  PDF  |  HTML  |  Order a Reprint

Identification of candidate genes related to pancreatic cancer based on analysis of gene co-expression and protein-protein interaction network

Identification of candidate genes related to pancreatic cancer based on analysis of gene co-expression and protein-protein interaction network

https://doi.org/10.18632/oncotarget.20537

Tiejun Zhang, Xiaojuan Wang,  and Zhenyu Yue
71105-71116
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Efficacy and safety of dose-dense chemotherapy in urothelial carcinoma

Efficacy and safety of dose-dense chemotherapy in urothelial carcinoma

https://doi.org/10.18632/oncotarget.16759

Chenjing Zhu, Jiaming Liu, Jing Zhang, Qingfang Li, Qisi Lian, Jing Xu,  and Xuelei Ma
71117-71127
Abstract  |  PDF  |  HTML  |  Order a Reprint

Imatinib dose escalation versus sunitinib as a second-line treatment against advanced gastrointestinal stromal tumors: A nationwide population-based cohort study

Imatinib dose escalation versus sunitinib as a second-line treatment against advanced gastrointestinal stromal tumors: A nationwide population-based cohort study

https://doi.org/10.18632/oncotarget.16795

Jun-Te Hsu, Puo-Hsien Le, Chang-Fu Kuo, Meng-Jiun Chiou, Chia-Jung Kuo, Tsung-Hsing Chen, Chun-Jung Lin, Jen-Shi Chen, Huang-Pin Yu, Chun-Nan Yeh, Yi-Yin Jan,  and Ta-Sen Yeh
71128-71137
Abstract  |  PDF  |  HTML  |  Order a Reprint

Nomograms incorporated serum direct bilirubin level for predicting prognosis in stages II and III colorectal cancer after radical resection

Nomograms incorporated serum direct bilirubin level for predicting prognosis in stages II and III colorectal cancer after radical resection

https://doi.org/10.18632/oncotarget.11424

Qunfeng Zhang, Xiaowei Ma, Qunhuan Xu, Juanxiu Qin, Yanhua Wang, Qian Liu, Hua Wang,  and Min Li
71138-71146
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Surgical resection for hepatic metastasis from gastric cancer: a multi-institution study

Surgical resection for hepatic metastasis from gastric cancer: a multi-institution study

https://doi.org/10.18632/oncotarget.16705

Ailin Song, Xiaofeng Zhang, Feng Yu, Debang Li, Wenyu Shao,  and Yanming Zhou
71147-71153
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The prognostic significance of preoperative left ventricular diastolic dysfunction and left atrial enlargement on acute coronary syndrome in kidney transplantation

The prognostic significance of preoperative left ventricular diastolic dysfunction and left atrial enlargement on acute coronary syndrome in kidney transplantation

https://doi.org/10.18632/oncotarget.16862

Jin Ho Hwang, Jun-Bean Park, Yong-Jin Kim, Jung Nam An, Jaeseok Yang, Curie Ahn, In Mok Jung, Chun Soo Lim, Yon Su Kim, Young Hoon Kim,  and Jung Pyo Lee
71154-71163
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RAS testing and cetuximab treatment for metastatic colorectal cancer: a cost-effectiveness analysis in a setting with limited health resources

RAS testing and cetuximab treatment for metastatic colorectal cancer: a cost-effectiveness analysis in a setting with limited health resources

https://doi.org/10.18632/oncotarget.17029

Bin Wu, Yuan Yao, Ke Zhang,  and Xuezhen Ma
71164-71172
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Combined efficacy of C-reactive protein and red blood cell distribution width in prognosis of patients with culture-negative infective endocarditis

Combined efficacy of C-reactive protein and red blood cell distribution width in prognosis of patients with culture-negative infective endocarditis

https://doi.org/10.18632/oncotarget.16888

Xue-Biao Wei, Yuan-Hui Liu, Peng-Cheng He, Ying-Ling Zhou, Ning Tan, Ji-Yan Chen,  and Dan-Qing Yu
71173-71180
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Phase I study of nivolumab combined with IFN-β for patients with advanced melanoma

Phase I study of nivolumab combined with IFN-β for patients with advanced melanoma

https://doi.org/10.18632/oncotarget.17090

Taku Fujimura, Takanori Hidaka, Yumi Kambayashi, Sadanori Furudate, Aya Kakizaki, Hisayuki Tono, Akira Tsukada, Takahiro Haga, Akira Hashimoto, Ryo Morimoto, Takuhiro Yamaguchi, Tadao Takano,  and Setsuya Aiba
71181-71187
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Dual time-point 18F-FDG PET/CT imaging with multiple metabolic parameters in the differential diagnosis of malignancy-suspected bone/joint lesions

Dual time-point 18F-FDG PET/CT imaging with multiple metabolic parameters in the differential diagnosis of malignancy-suspected bone/joint lesions

https://doi.org/10.18632/oncotarget.17140

Chen-Tian Shen, Zhong-Ling Qiu, Zhen-Kui Sun, Wei-Jun Wei, Hong-Jun Song, Xin-Yun Zhang,  and Quan-Yong Luo
71188-71196
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Negative lymph node count is a significant prognostic factor in patient with stage IV gastric cancer after palliative gastrectomy

Negative lymph node count is a significant prognostic factor in patient with stage IV gastric cancer after palliative gastrectomy

https://doi.org/10.18632/oncotarget.17430

Changhua Zhuo, Mingang Ying, Ruirong Lin, Xianyi Wu, Shen Guan,  and Chunkang Yang
71197-71205
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Reviews

OncomiR-17-5p: alarm signal in cancer?

OncomiR-17-5p: alarm signal in cancer?

https://doi.org/10.18632/oncotarget.19331

Madhusudhan Reddy Bobbili, Robert M. Mader, Johannes Grillari,  and Hanna Dellago
71206-71222
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State-of-the-art considerations in small cell lung cancer brain metastases

State-of-the-art considerations in small cell lung cancer brain metastases

https://doi.org/10.18632/oncotarget.19333

Rimas V. Lukas, Vinai Gondi, David O. Kamson, Priya Kumthekar,  and Ravi Salgia
71223-71233
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Next-generation sequencing in chronic lymphocytic leukemia: recent findings and new horizons

Next-generation sequencing in chronic lymphocytic leukemia: recent findings and new horizons

https://doi.org/10.18632/oncotarget.19525

Ana E. Rodríguez-Vicente, Vasilis Bikos, María Hernández-Sánchez, Jitka Malcikova, Jesús-María Hernández-Rivas,  and Sarka Pospisilova
71234-71248
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Immunomodulatory and antitumor effects of type I interferons and their application in cancer therapy

Immunomodulatory and antitumor effects of type I interferons and their application in cancer therapy

https://doi.org/10.18632/oncotarget.19531

Ruan F.V. Medrano, Aline Hunger, Samir Andrade Mendonça, José Alexandre M. Barbuto,  and Bryan E. Strauss
71249-71284
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BET inhibitors as novel therapeutic agents in breast cancer

BET inhibitors as novel therapeutic agents in breast cancer

https://doi.org/10.18632/oncotarget.19744

Alberto Ocaña, Cristina Nieto-Jiménez,  and Atanasio Pandiella
71285-71291
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miR-708-5p: a microRNA with emerging roles in cancer

miR-708-5p: a microRNA with emerging roles in cancer

https://doi.org/10.18632/oncotarget.19772

Nicholas J. Monteleone,  and Carol S. Lutz
71292-71316
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Role of PLZF as a tumor suppressor in prostate cancer

Role of PLZF as a tumor suppressor in prostate cancer

https://doi.org/10.18632/oncotarget.19813

Yang Jin, Hatice Zeynep Nenseth,  and Fahri Saatcioglu
71317-71324
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LncRNAs: key players and novel insights into diabetes mellitus

LncRNAs: key players and novel insights into diabetes mellitus

https://doi.org/10.18632/oncotarget.19921

Xiaoyun He, Chunlin Ou, Yanhua Xiao, Qing Han, Hao Li,  and Suxian Zhou
71325-71341
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Mitochondrial genome variation and prostate cancer: a review of the mutational landscape and application to clinical management

Mitochondrial genome variation and prostate cancer: a review of the mutational landscape and application to clinical management

https://doi.org/10.18632/oncotarget.19926

Anton M.F. Kalsbeek, Eva K.F. Chan, Niall M. Corcoran, Christopher M. Hovens,  and Vanessa M. Hayes
71342-71357
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The resistance mechanisms and treatment strategies for EGFR-mutant advanced non-small-cell lung cancer

The resistance mechanisms and treatment strategies for EGFR-mutant advanced non-small-cell lung cancer

https://doi.org/10.18632/oncotarget.20311

Wen-Zhao Zhong, Qing Zhou,  and Yi-Long Wu
71358-71370
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Research Papers

Expression and clinical association of programmed cell death-1, programmed death-ligand-1 and CD8+ lymphocytes in primary sarcomas is subtype dependent

Expression and clinical association of programmed cell death-1, programmed death-ligand-1 and CD8+ lymphocytes in primary sarcomas is subtype dependent

https://doi.org/10.18632/oncotarget.19071

Anke E.M. van Erp, Yvonne M.H. Versleijen-Jonkers, Melissa H.S. Hillebrandt-Roeffen, Laurens van Houdt, Mark A.J. Gorris, Laura S. van Dam, Thomas Mentzel, Marije E. Weidema, C. Dilara Savci-Heijink, Ingrid M.E. Desar, Hans H.M. Merks, Max M. van Noesel, Janet Shipley, Winette T.A. van der Graaf, Uta E. Flucke,  and Friederike A.G. Meyer-Wentrup
71371-71384
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