Oncotarget

VOLUME 7 (2016)

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About The Cover

The cover for issue 39 of Oncotarget features Figure 6D (Systemic GSI-I decreases growth of NB xenografts and is associated with mitotic catastrophe, decreased proliferation and reduced tumor angiogenesis) from Dorneburg, et al.

Table of Contents

Editorial

Recent developments in vertical transmission of ZIKA virus

https://doi.org/10.18632/oncotarget.11619
62797-62798
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Priority Research Papers

γsecretase inhibitor I inhibits neuroblastoma cells with NOTCH and the proteasome among its targets

https://doi.org/10.18632/oncotarget.11715
62799-62813
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Acquisition of an oncogenic fusion protein serves as an initial driving mutation by inducing aneuploidy and overriding proliferative defects

https://doi.org/10.18632/oncotarget.11716
62814-62835
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Gerotarget (Focus on Aging)

A steroid like phytochemical Antcin M is an antiaging reagent that eliminates hyperglycemiaaccelerated premature senescence in dermal fibroblasts by direct activation of Nrf2 and SIRT1

https://doi.org/10.18632/oncotarget.11229
62836-62861
Abstract  |  PDF  |  Full Text  |  How to cite

Blunted dynamics of adenosine A2A receptors is associated with increased susceptibility to Candida albicans infection in the elderly

https://doi.org/10.18632/oncotarget.11760
62862-62872
Abstract  |  PDF  |  Full Text  |  How to cite

Transfection of the IHH gene into rabbit BMSCs in a simulated microgravity environment promotes chondrogenic differentiation and inhibits cartilage aging

https://doi.org/10.18632/oncotarget.11871
62873-62885
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Research Papers: Pathology

Long noncoding RNA PVT1 activates hepatic stellate cells through competitively binding microRNA152

https://doi.org/10.18632/oncotarget.11709
62886-62897
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Immunology

Racerelated differences in antibody responses to the inactivated influenza vaccine are linked to distinct prevaccination gene expression profiles in blood

https://doi.org/10.18632/oncotarget.11704
62898-62911
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Autophagy and Cell Death

A potential molecular model for studying apoptosis enhanced by the interaction of BCLG with JAB1 in swine

https://doi.org/10.18632/oncotarget.11230
62912-62924
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Research Papers

Targeting FXYD2 by cardiac glycosides potently blocks tumor growth in ovarian clear cell carcinoma

https://doi.org/10.18632/oncotarget.7497
62925-62938
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Systematic analysis of tumour cellextracellular matrix adhesion identifies independent prognostic factors in breast cancer

https://doi.org/10.18632/oncotarget.11307
62939-62953
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Two common functional catalase gene polymorphisms rs1001179 and rs794316 and cancer susceptibility: evidence from 14942 cancer cases and 43285 controls

https://doi.org/10.18632/oncotarget.10617
62954-62965
Abstract  |  PDF  |  Full Text  |  How to cite

Clinicopathological and prognostic significance of metastasisassociated in colon cancer1 MACC1 overexpression in colorectal cancer: a metaanalysis

https://doi.org/10.18632/oncotarget.11287
62966-62975
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The effect of epigenetic silencing and TP53 mutation on the expression of DLL4 in human cancer stem disorder

https://doi.org/10.18632/oncotarget.11316
62976-62988
Abstract  |  PDF  |  Full Text  |  How to cite

Molecular dissection of the valproic acid effects on glioma cells

https://doi.org/10.18632/oncotarget.11379
62989-63002
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Gene expression signature based screening identifies ribonucleotide reductase as a candidate therapeutic target in Ewing sarcoma

https://doi.org/10.18632/oncotarget.11416
63003-63019
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Reversibility of glioma stem cells’ phenotypes explains their complex in vitro and in vivo behavior: Discovery of a novel neurospherespecific enzyme cGMPdependent protein kinase 1 using the genomic landscape of human glioma stem cells as a discovery tool

https://doi.org/10.18632/oncotarget.11589
63020-63041
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prognostic impact of the expression of Wntsignaling proteins in cervical carcinoma FIGO stage IIV treated with radiotherapy or chemoradiotherapy

https://doi.org/10.18632/oncotarget.11642
63042-63053
Abstract  |  PDF  |  Full Text  |  How to cite

Effect of epidermal growth factor receptor gene polymorphisms on prognosis in glioma patients

https://doi.org/10.18632/oncotarget.10666
63054-63064
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Targeted suppression of ARV7 using PIP5K1α inhibitor overcomes enzalutamide resistance in prostate cancer cells

https://doi.org/10.18632/oncotarget.11757
63065-63081
Abstract  |  PDF  |  Full Text  |  How to cite

Clues toward precision medicine in oral squamous cell carcinoma: utility of nextgeneration sequencing for the prognostic stratification of highrisk patients harboring neck lymph node extracapsular extension

https://doi.org/10.18632/oncotarget.11762
63082-63092
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Visceral fat adipocytes from obese and colorectal cancer subjects exhibit distinct secretory and ω6 polyunsaturated fatty acid profiles and deliver immunosuppressive signals to innate immunity cells

https://doi.org/10.18632/oncotarget.10998
63093-63105
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Phosphatidylinositide 3kinase PI3K and PI3Krelated kinase PIKK activity contributes to radioresistance in thyroid carcinomas

https://doi.org/10.18632/oncotarget.11056
63106-63123
Abstract  |  PDF  |  Full Text  |  How to cite

DDA suppresses angiogenesis and tumor growth of colorectal cancer in vivo through decreasing VEGFR2 signaling

https://doi.org/10.18632/oncotarget.11152
63124-63137
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Hypoxia enhances the malignant nature of bladder cancer cells and concomitantly antagonizes protein Oglycosylation extension

https://doi.org/10.18632/oncotarget.11257
63138-63157
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Altered phosphatidylcholines expression in sputum for diagnosis of nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.11283
63158-63165
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Landscape of RNAs in human lumbar disc degeneration

https://doi.org/10.18632/oncotarget.11334
63166-63176
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Distinct mutation profile and prognostic relevance in patients with hypoplastic myelodysplastic syndromes hMDS

https://doi.org/10.18632/oncotarget.11050
63177-63188
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Validation of a networkbased strategy for the optimization of combinatorial target selection in breast cancer therapy: siRNA knockdown of network targets in MDAMB231 cells as an in vitro model for inhibition of tumor development

https://doi.org/10.18632/oncotarget.11055
63189-63203
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Immunosuppressive effect of bladder cancer on function of dendritic cells involving of Jak2/STAT3 pathway

https://doi.org/10.18632/oncotarget.11434
63204-63214
Abstract  |  PDF  |  Full Text  |  How to cite

FAM65B controls the proliferation of transformed and primary T cells

https://doi.org/10.18632/oncotarget.11438
63215-63225
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Therapeutic dosages of aspirin counteract the IL6 induced protumorigenic effects by slowing down the ribosome biogenesis rate

https://doi.org/10.18632/oncotarget.11441
63226-63241
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The double benefit of Spalax p53: surviving underground hypoxia while defying lung cancer cells in vitro via autophagy and caspasedependent cell death

https://doi.org/10.18632/oncotarget.11443
63242-63251
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Target sequencing and CRISPR/Cas editing reveal simultaneous loss of UTX and UTY in urothelial bladder cancer

https://doi.org/10.18632/oncotarget.11207
63252-63260
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

RORα and RORγ expression inversely correlates with human melanoma progression

https://doi.org/10.18632/oncotarget.11211
63261-63282
Abstract  |  PDF  |  Full Text  |  How to cite

The accuracy of microRNA210 in diagnosing lung cancer: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.11446
63283-63293
Abstract  |  PDF  |  Full Text  |  How to cite

Decreased TSPAN1 promotes prostate cancer progression and is a marker for early biochemical recurrence after radical prostatectomy

https://doi.org/10.18632/oncotarget.11448
63294-63305
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MetAP1 and MetAP2 drive cell selectivity for a potent anticancer agent in synergy by controlling glutathione redox state

https://doi.org/10.18632/oncotarget.11216
63306-63323
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Sphingosine1phosphate induced epithelialmesenchymal transition of hepatocellular carcinoma via an MMP7/ syndecan1/TGFβ autocrine loop

https://doi.org/10.18632/oncotarget.11450
63324-63337
Abstract  |  PDF  |  Full Text  |  How to cite

Correlation between body mass index BMI and the Gleason score of prostate biopsies in Chinese population

https://doi.org/10.18632/oncotarget.11453
63338-63341
Abstract  |  PDF  |  Full Text  |  How to cite

Rab27A mediated by NFκB promotes the stemness of colon cancer cells via upregulation of cytokine secretion

https://doi.org/10.18632/oncotarget.11454
63342-63351
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Mel18 negatively regulates stem celllike properties through downregulation of miR21 in gastric cancer

https://doi.org/10.18632/oncotarget.11221
63352-63361
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Control of translational activation by PIM kinase in activated Bcell diffuse large Bcell lymphoma confers sensitivity to inhibition by PIM447

https://doi.org/10.18632/oncotarget.11457
63362-63373
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Adrenomedullin blockade suppresses sunitinibresistant renal cell carcinoma growth by targeting the ERK/MAPK pathway

https://doi.org/10.18632/oncotarget.11463
63374-63387
Abstract  |  PDF  |  Full Text  |  How to cite

Identification of tumorigenesisrelated mRNAs associated with RNAbinding protein HuR in thyroid cancer cells

https://doi.org/10.18632/oncotarget.11255
63388-63407
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Altered pH gradient at the plasma membrane of osteosarcoma cells is a key mechanism of drug resistance

https://doi.org/10.18632/oncotarget.11503
63408-63423
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Epigenetic changes in localized gastric cancer: the role of RUNX3 in tumor progression and the immune microenvironment

https://doi.org/10.18632/oncotarget.11520
63424-63436
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Nontargeted and targeted metabolomics approaches to diagnosing lung cancer and predicting patient prognosis

https://doi.org/10.18632/oncotarget.11521
63437-63448
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Silencing of cZNF292 circular RNA suppresses human glioma tube formation via the Wnt/βcatenin signaling pathway

https://doi.org/10.18632/oncotarget.11523
63449-63455
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Subclones in Blymphoma cell lines: isogenic models for the study of gene regulation

https://doi.org/10.18632/oncotarget.11524
63456-63465
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Integrin β1 myosin light chain kinase and myosin IIA are required for activation of PI3KAKT signaling following MEK inhibition in metastatic triple negative breast cancer

https://doi.org/10.18632/oncotarget.11525
63466-63487
Abstract  |  PDF  |  Full Text  |  How to cite

Construction and immunological characterization of CD40L or GMCSF incorporated Hantaan virus like particle

https://doi.org/10.18632/oncotarget.11329
63488-63503
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Differential IgM expression distinguishes two types of pediatric Burkitt lymphoma in mouse and human

https://doi.org/10.18632/oncotarget.11531
63504-63513
Abstract  |  PDF  |  Full Text  |  How to cite

Peptidome analysis of human milk from women delivering macrosomic fetuses reveals multiple means of protection for infants

https://doi.org/10.18632/oncotarget.11532
63514-63525
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A novel molecular and clinical staging model to predict survival for patients with esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.11362
63526-63536
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Secretome proteomics reveals candidate noninvasive biomarkers of BRCA1 deficiency in breast cancer

https://doi.org/10.18632/oncotarget.11535
63537-63548
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Novel synthetic cyclic integrin αvβ3 binding peptide ALOS4: antitumor activity in mouse melanoma models

https://doi.org/10.18632/oncotarget.11363
63549-63560
Abstract  |  PDF  |  Full Text  |  How to cite

Long noncoding RNA HoxAAS3 interacts with EZH2 to regulate lineage commitment of mesenchymal stem cells

https://doi.org/10.18632/oncotarget.11538
63561-63570
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

HER2 amplification level is not a prognostic factor for HER2positive breast cancer with trastuzumabbased adjuvant treatment: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.11541
63571-63582
Abstract  |  PDF  |  Full Text  |  How to cite

The ω3 polyunsaturated fatty acids prevented colitisassociated carcinogenesis through blocking dissociation of βcatenin complex inhibiting COX2 through repressing NFκB and inducing 15prostaglandin dehydrogenase

https://doi.org/10.18632/oncotarget.11544
63583-63595
Abstract  |  PDF  |  Full Text  |  How to cite

ERMP1 a novel potential oncogene involved in UPR and oxidative stress defense is highly expressed in human cancer

https://doi.org/10.18632/oncotarget.11550
63596-63610
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Numblike NumbL downregulation increases tumorigenicity cancer stem celllike properties and resistance to chemotherapy

https://doi.org/10.18632/oncotarget.11553
63611-63628
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Protein arginine methyltransferase 1 is a novel regulator of MYCN in neuroblastoma

https://doi.org/10.18632/oncotarget.11556
63629-63639
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Common genetic variations in cell cycle and DNA repair pathways associated with pediatric brain tumor susceptibility

https://doi.org/10.18632/oncotarget.11575
63640-63650
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

NOD2 upregulates TLR2mediated IL23p19 expression via NFκB subunit cRel in Paneth celllike cells

https://doi.org/10.18632/oncotarget.11467
63651-63660
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

High CLEC2 expression associates with unfavorable postoperative prognosis of patients with clear cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.11606
63661-63668
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Expression of immune checkpoints in T cells of esophageal cancer patients

https://doi.org/10.18632/oncotarget.11611
63669-63678
Abstract  |  PDF  |  Full Text  |  How to cite

Leucine deprivation inhibits proliferation and induces apoptosis of human breast cancer cells via fatty acid synthase

https://doi.org/10.18632/oncotarget.11626
63679-63689
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Hypoxia inducible factor1 mediates the expression of the immune checkpoint HLAG in glioma cells through hypoxia response element located in exon 2

https://doi.org/10.18632/oncotarget.11628
63690-63707
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

New role of osteopontin in DNA repair and impact on human glioblastoma radiosensitivity

https://doi.org/10.18632/oncotarget.11483
63708-63721
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Effectiveness of capecitabine with or without docetaxel therapy for the treatment of patients with advanced urothelial carcinoma: a singleinstitution experience

https://doi.org/10.18632/oncotarget.11641
63722-63729
Abstract  |  PDF  |  Full Text  |  How to cite

CEACAM1 controls the EMT switch in murine mammary carcinoma in vitro and in vivo

https://doi.org/10.18632/oncotarget.11650
63730-63746
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

[11C]Choline PET/CT in therapy response assessment of a neoadjuvant therapy in locally advanced and high risk prostate cancer before radical prostatectomy

https://doi.org/10.18632/oncotarget.11653
63747-63757
Abstract  |  PDF  |  Full Text  |  How to cite

Gene status and clinicopathologic characteristics of lung adenocarcinomas with mediastinal lymph node metastasis

https://doi.org/10.18632/oncotarget.11494
63758-63766
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

RSPOs facilitated HSC activation and promoted hepatic fibrogenesis

https://doi.org/10.18632/oncotarget.11654
63767-63778
Abstract  |  PDF  |  Full Text  |  How to cite

RSL3 and Erastin differentially regulate redox signaling to promote Smac mimeticinduced cell death

https://doi.org/10.18632/oncotarget.11687
63779-63792
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

NKAIN2 functions as a novel tumor suppressor in prostate cancer

https://doi.org/10.18632/oncotarget.11690
63793-63803
Abstract  |  PDF  |  Full Text  |  How to cite

Mycobacterium tuberculosis multistage antigens confer comprehensive protection against pre and postexposure infections by driving Th1type T cell immunity

https://doi.org/10.18632/oncotarget.11542
63804-63815
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Essential role of Na+/Ca2+ exchanger 1 in smokinginduced growth and migration of esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.11695
63816-63828
Abstract  |  PDF  |  Full Text  |  How to cite

Differential effects of histone deacetylase inhibitors on cellular drug transporters and their implications for using epigenetic modifiers in combination chemotherapy

https://doi.org/10.18632/oncotarget.11561
63829-63838
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Induction of VEGFA and Snail1 by meningitic Escherichia coli mediates disruption of the bloodbrain barrier

https://doi.org/10.18632/oncotarget.11696
63839-63855
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Lipid rafts promote liver cancer cell proliferation and migration by upregulation of TLR7 expression

https://doi.org/10.18632/oncotarget.11697
63856-63869
Abstract  |  PDF  |  Full Text  |  How to cite

Curcumin potentiates antitumor activity of cisplatin in bladder cancer cell lines via ROSmediated activation of ERK1/2

https://doi.org/10.18632/oncotarget.11563
63870-63886
Abstract  |  PDF  |  Full Text  |  How to cite

FAM122A a new endogenous inhibitor of protein phosphatase 2A

https://doi.org/10.18632/oncotarget.11698
63887-63900
Abstract  |  PDF  |  Full Text  |  How to cite

Long noncoding RNA MALAT1 acts as a competing endogenous RNA to promote malignant melanoma growth and metastasis by sponging miR22

https://doi.org/10.18632/oncotarget.11564
63901-63912
Abstract  |  PDF  |  Full Text  |  How to cite

Autophagy regulates the survival of cells with chromosomal instability

https://doi.org/10.18632/oncotarget.11736
63913-63923
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A novel application of E1A in combination therapy with EGFRTKI treatment in breast cancer

https://doi.org/10.18632/oncotarget.11737
63924-63936
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Comparative profiling between primary colorectal carcinomas and metastases identifies heterogeneity on drug resistance

https://doi.org/10.18632/oncotarget.11570
63937-63949
Abstract  |  PDF  |  Full Text  |  How to cite

Transcriptomic and functional pathways analysis of ascorbateinduced cytotoxicity and resistance of Burkitt lymphoma

https://doi.org/10.18632/oncotarget.11740
63950-63959
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The LSP1 rs3817198 T > C polymorphism contributes to increased breast cancer risk: a metaanalysis of twelve studies

https://doi.org/10.18632/oncotarget.11741
63960-63967
Abstract  |  PDF  |  Full Text  |  How to cite

Prognostic value of metabolic parameters on preoperative 18FFluorodeoxyglucose positron emission tomography/ computed tomography in patients with stage III gastric cancer

https://doi.org/10.18632/oncotarget.11574
63968-63980
Abstract  |  PDF  |  Full Text  |  How to cite

LL202 protects against dextran sulfate sodiuminduced experimental colitis in mice by inhibiting MAPK/AP1 signaling

https://doi.org/10.18632/oncotarget.11742
63981-63994
Abstract  |  PDF  |  Full Text  |  How to cite

Modeling of signaling crosstalkmediated drug resistance and its implications on drug combination

https://doi.org/10.18632/oncotarget.11745
63995-64006
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Gata3 restrains B cell proliferation and cooperates with p18INK4c to repress B cell lymphomagenesis

https://doi.org/10.18632/oncotarget.11746
64007-64020
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Leptin induces osteocalcin expression in ATDC5 cells through activation of the MAPKERK1/2 signaling pathway

https://doi.org/10.18632/oncotarget.11578
64021-64029
Abstract  |  PDF  |  Full Text  |  How to cite

Defective CFTR βcatenin interaction promotes NFκB nuclear translocation and intestinal inflammation in cystic fibrosis

https://doi.org/10.18632/oncotarget.11747
64030-64042
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Methylation and expression of PTPN22 in esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.11581
64043-64052
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Simple and robust diagnosis of early small and AFPnegative primary hepatic carcinomas: an integrative approach of serum fluorescence and conventional blood tests

https://doi.org/10.18632/oncotarget.11771
64053-64070
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Deep targeted sequencing in pediatric acute lymphoblastic leukemia unveils distinct mutational patterns between genetic subtypes and novel relapseassociated genes

https://doi.org/10.18632/oncotarget.11773
64071-64088
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Phase Ib/II randomized openlabel study of doxorubicin and cyclophosphamide with or without lowdose shortcourse sunitinib in the preoperative treatment of breast cancer

https://doi.org/10.18632/oncotarget.11596
64089-64099
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR19b suppresses PTPRG to promote breast tumorigenesis

https://doi.org/10.18632/oncotarget.11799
64100-64108
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PARP3 controls TGFβ and ROS driven epithelialtomesenchymal transition and stemness by stimulating a TG2SnailEcadherin axis

https://doi.org/10.18632/oncotarget.11627
64109-64123
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Dual role of the integrated stress response in medulloblastoma tumorigenesis

https://doi.org/10.18632/oncotarget.11873
64124-64135
Abstract  |  PDF  |  Full Text  |  How to cite

Regorafenib Stivarga pharmacologically targets epithelialmesenchymal transition in colorectal cancer

https://doi.org/10.18632/oncotarget.11636
64136-64147
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Comprehensive characterization of lncRNAmRNA related ceRNA network across 12 major cancers

https://doi.org/10.18632/oncotarget.11637
64148-64167
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Coupling CDH17 and CLDN18 markers for comprehensive membranetargeted detection of human gastric cancer

https://doi.org/10.18632/oncotarget.11638
64168-64181
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Biologic behavior and longterm outcomes of breast ductal carcinoma in situ with microinvasion

https://doi.org/10.18632/oncotarget.11639
64182-64190
Abstract  |  PDF  |  Full Text  |  How to cite

DNA methylation array analysis identifies breast cancer associated RPTOR MGRN1 and RAPSN hypomethylation in peripheral blood DNA

https://doi.org/10.18632/oncotarget.11640
64191-64202
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

F5peptide induces aspermatogenesis by disrupting organization of actin and microtubulebased cytoskeletons in the testis

https://doi.org/10.18632/oncotarget.11887
64203-64220
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

AAAATPase p97 suppresses apoptotic and autophagyassociated cell death in rheumatoid arthritis synovial fibroblasts

https://doi.org/10.18632/oncotarget.11890
64221-64232
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Circulating serum microRNA345 correlates with unfavorable pathological response to preoperative chemoradiotherapy in locally advanced rectal cancer

https://doi.org/10.18632/oncotarget.11649
64233-64243
Abstract  |  PDF  |  Full Text  |  How to cite

Regulation of matrix metalloproteinases MMPs expression and secretion in MDAMB231 breast cancer cells by LIM and SH3 protein 1 LASP1

https://doi.org/10.18632/oncotarget.11720
64244-64259
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Loss of Par3 promotes lung adenocarcinoma metastasis through 1433ζ protein

https://doi.org/10.18632/oncotarget.11728
64260-64273
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Activation of the A2B adenosine receptor in B16 melanomas induces CXCL12 expression in FAPpositive tumor stromal cells enhancing tumor progression

https://doi.org/10.18632/oncotarget.11729
64274-64288
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

DMBA induced mouse mammary tumors display high incidence of activating Pik3caH1047 and loss of function Pten mutations

https://doi.org/10.18632/oncotarget.11733
64289-64299
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Characterizing the immune microenvironment of malignant peripheral nerve sheath tumor by PDL1 expression and presence of CD8+ tumor infiltrating lymphocytes

https://doi.org/10.18632/oncotarget.11734
64300-64308
Abstract  |  PDF  |  Full Text  |  How to cite

Lipocalin 2 overexpression facilitates progress of castrationresistant prostate cancer via improving androgen receptor transcriptional activity

https://doi.org/10.18632/oncotarget.11790
64309-64317
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Expressions of CD8+TILs PDL1 and Foxp3+TILs in stage I NSCLC guiding adjuvant chemotherapy decisions

https://doi.org/10.18632/oncotarget.11793
64318-64329
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The iron chelator deferasirox induces apoptosis by targeting oncogenic Pyk2/βcatenin signaling in human multiple myeloma

https://doi.org/10.18632/oncotarget.11830
64330-64341
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The TATRasGAP317326 anticancer peptide can kill in a caspase apoptosis and necroptosisindependent manner

https://doi.org/10.18632/oncotarget.11841
64342-64359
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Overexpression of PHRF1 attenuates the proliferation and tumorigenicity of nonsmall cell lung cancer cells

https://doi.org/10.18632/oncotarget.11842
64360-64370
Abstract  |  PDF  |  Full Text  |  How to cite

Circulating levels of Creactive protein interleukin6 and tumor necrosis factorα and risk of colorectal adenomas: a metaanalysis

https://doi.org/10.18632/oncotarget.11853
64371-64379
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinical Research Papers

Association between gallbladder stone disease and prostate cancer: A nationwide populationbased study

https://doi.org/10.18632/oncotarget.9062
64380-64389
Abstract  |  PDF  |  Full Text  |  How to cite

A phase I study of intratumoral ipilimumab and interleukin2 in patients with advanced melanoma

https://doi.org/10.18632/oncotarget.10453
64390-64399
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Alternative treatments in advanced hepatocellular carcinoma patients with progressive disease after sorafenib treatment: a prospective multicenter cohort study

https://doi.org/10.18632/oncotarget.10794
64400-64409
Abstract  |  PDF  |  Full Text  |  How to cite

Responses to crizotinib in patients with ALKpositive lung adenocarcinoma who tested immunohistochemistry IHCpositive and fluorescence in situ hybridization FISHnegative

https://doi.org/10.18632/oncotarget.10560
64410-64420
Abstract  |  PDF  |  Full Text  |  How to cite

Validation of prognostic scoring and assessment of clinical benefit for patients with bone sarcomas enrolled in phase I clinical trials

https://doi.org/10.18632/oncotarget.10910
64421-64430
Abstract  |  PDF  |  Full Text  |  How to cite

Reviews

Mechanisms of resistance and sensitivity to antiHER2 therapies in HER2+ breast cancer

https://doi.org/10.18632/oncotarget.7043
64431-64446
Abstract  |  PDF  |  Full Text  |  How to cite

Molecular mechanisms underlying resistance to androgen deprivation therapy in prostate cancer

https://doi.org/10.18632/oncotarget.10901
64447-64470
Abstract  |  PDF  |  Full Text  |  How to cite
Special Collection ToC

Ubc13: the Lys63 ubiquitin chain building machine

https://doi.org/10.18632/oncotarget.10948
64471-64504
Abstract  |  PDF  |  Full Text  |  How to cite

Suppressive role of myeloidderived suppressor cells MDSCs in the microenvironment of breast cancer and targeted immunotherapies

https://doi.org/10.18632/oncotarget.11352
64505-64511
Abstract  |  PDF  |  Full Text  |  How to cite

The emerging insights into catalytic or noncatalytic roles of TET proteins in tumors and neural development

https://doi.org/10.18632/oncotarget.11412
64512-64525
Abstract  |  PDF  |  Full Text  |  How to cite

Corrections

Correction: Cyclin D1 silencing suppresses tumorigenicity impairs DNA double strand break repair and thus radiosensitizes androgenindependent prostate cancer cells to DNA damage

https://doi.org/10.18632/oncotarget.12267
64526-64526
Correction  |  PDF  |  How to cite


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