Oncotarget

Vol 13 (2022)

Table of Contents

Research Papers

Transcriptomics reveals in vivo efficacy of PARP inhibitor combinatorial synergy with platinum-based chemotherapy in human non-small cell lung carcinoma models

Transcriptomics reveals in vivo efficacy of PARP inhibitor combinatorial synergy with platinum-based chemotherapy in human non-small cell lung carcinoma models

https://doi.org/10.18632/oncotarget.28162

Lindsay R. Stolzenburg, Barrett Ainsworth, Bridget Riley-Gillis, Tibor Pakozdi, Areej Ammar, Paul A. Ellis, Julie L. Wilsbacher,  and Cyril Y. Ramathal
1-12
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Editorial

Unravelling the underpinnings of hyperprogression and immunotherapy: back to the bench

Unravelling the underpinnings of hyperprogression and immunotherapy: back to the bench

https://doi.org/10.18632/oncotarget.28098

Vivek Subbiah,  and Razelle Kurzrock
13-15
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Commentaries

Oxygen-independent, CDK4/CDK6-dependent degradation of hypoxia-inducible factor-1α takes cancers’ breath away

Oxygen-independent, CDK4/CDK6-dependent degradation of hypoxia-inducible factor-1α takes cancers’ breath away

https://doi.org/10.18632/oncotarget.28166

Len Neckers
16-17
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Research Perspectives

The “Immunoscore” in rectal cancer: could we search quality beyond quantity of life?

The “Immunoscore” in rectal cancer: could we search quality beyond quantity of life?

https://doi.org/10.18632/oncotarget.28100

Amos Kirilovsky, Carine El Sissy, Guy Zeitoun, Florence Marliot, Nacilla Haicheur, Christine Lagorce-Pagès, Julien Taieb, Mehdi Karoui, Petra Custers, Edina Dizdarevic, Soledad Iseas, Torben Frøstrup Hansen, Lars Henrik Jensen, Geerard Beets, Jean Pierre Gérard, Mireia Castillo-Martin, Nuno Figueiredo, Angelita Habr-Gama, Rodrigo Perez, Jérôme Galon,  and Franck Pagès
18-31
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release  |  Order a Reprint

Research Papers

Induction of serine hydroxymethyltransferase 2 promotes tumorigenesis and metastasis in neuroblastoma

Induction of serine hydroxymethyltransferase 2 promotes tumorigenesis and metastasis in neuroblastoma

https://doi.org/10.18632/oncotarget.28168

Rachael A. Clark, Jingbo Qiao, Jillian C. Jacobson,  and Dai H. Chung
32-45
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Research Papers

The androgen receptor inhibits transcription of GPER1 by preventing Sp1 and Sp3 from binding to the promoters in prostate cancer cells

The androgen receptor inhibits transcription of GPER1 by preventing Sp1 and Sp3 from binding to the promoters in prostate cancer cells

https://doi.org/10.18632/oncotarget.28169

Austin McDermott, KyoungHyun Kim, Susan Kasper, Shuk-Mei Ho,  and Yuet-Kin Leung
46-60
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Research Papers

Early detection of treatment futility in patients with metastatic colorectal cancer

Early detection of treatment futility in patients with metastatic colorectal cancer

https://doi.org/10.18632/oncotarget.28165

Jodi I. Rattner, Karen A. Kopciuk, Hans J. Vogel, Patricia A. Tang, Jeremy D. Shapiro, Dongsheng Tu, Derek J. Jonker, Lillian L. Siu, Chris J. O’Callaghan,  and Oliver F. Bathe
61-72
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Research Papers

Altered glycosylation of several metastasis-associated glycoproteins with terminal GalNAc defines the highly invasive cancer cell phenotype

Altered glycosylation of several metastasis-associated glycoproteins with terminal GalNAc defines the highly invasive cancer cell phenotype

https://doi.org/10.18632/oncotarget.28167

Elham Khosrowabadi, Tomasz Wenta, Salla Keskitalo, Aki Manninen,  and Sakari Kellokumpu
73-89
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Editorial

Are 50 years enough to prove the brilliant Dilman’s idea?

Are 50 years enough to prove the brilliant Dilman’s idea?

https://doi.org/10.18632/oncotarget.28097

Vladimir N. Anisimov
90-91
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Research Papers

GZ17-6.02 and palbociclib interact to kill ER+ breast cancer cells

GZ17-6.02 and palbociclib interact to kill ER+ breast cancer cells

https://doi.org/10.18632/oncotarget.28177

Laurence Booth, Cameron West, Robert P. Moore, Daniel Von Hoff,  and Paul Dent
92-104

Research Papers

Exploiting protein family and protein network data to identify novel drug targets for bladder cancer

Exploiting protein family and protein network data to identify novel drug targets for bladder cancer

https://doi.org/10.18632/oncotarget.28175

Tolulope Tosin Adeyelu, Aurelio A. Moya-Garcia,  and Christine Orengo
105-117
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Corrections

Correction: Prediction of survival prognosis of non-small cell lung cancer by APE1 through regulation of epithelial-mesenchymal transition

Correction: Prediction of survival prognosis of non-small cell lung cancer by APE1 through regulation of epithelial-mesenchymal transition

https://doi.org/10.18632/oncotarget.28141

Xi Wei, Qing Li, Ying Li, Wei Duan, Chongbiao Huang, Xiangqian Zheng, Lei Sun, Jingtao Luo, Dong Wang, Sheng Zhang, Xiaojie Xin,  and Ming Gao
118-119
Correction  |  PDF  |  How to cite

Commentaries

Redefining and expanding the sphere of influence of BRCA in breast and colorectal cancers and beyond

Redefining and expanding the sphere of influence of BRCA in breast and colorectal cancers and beyond

https://doi.org/10.18632/oncotarget.28164

Emil Lou
120-121
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Research Papers

Suppressive GLI2 fragment enhances liver metastasis in colorectal cancer

Suppressive GLI2 fragment enhances liver metastasis in colorectal cancer

https://doi.org/10.18632/oncotarget.28170

Ruiko Ogata, Shiori Mori, Hitoshi Ohmori, Shingo Kishi, Rina Fujiwara-Tani, Takamitsu Sasaki, Yukiko Nishiguchi, Chie Nakashima, Kei Goto, Isao Kawahara, Yi Luo,  and Hiroki Kuniyasu
122-135
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Research Papers

Chimeric chromosome landscapes of human somatic cell cultures show dependence on stress and regulation of genomic repeats by CGGBP1

Chimeric chromosome landscapes of human somatic cell cultures show dependence on stress and regulation of genomic repeats by CGGBP1

https://doi.org/10.18632/oncotarget.28174

Subhamoy Datta, Manthan Patel, Sukesh Kashyap, Divyesh Patel,  and Umashankar Singh
136-155
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Research Papers

Synthesis of a novel nanobioconjugate for targeted photodynamic therapy of colon cancer enhanced with cannabidiol

Synthesis of a novel nanobioconjugate for targeted photodynamic therapy of colon cancer enhanced with cannabidiol

https://doi.org/10.18632/oncotarget.28171

Nkune Williams Nkune, Cherie Ann Kruger,  and Heidi Abrahamse
156-172
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Meeting Reports

Seventh BHD international symposium: recent scientific and clinical advancement

Seventh BHD international symposium: recent scientific and clinical advancement

https://doi.org/10.18632/oncotarget.28176

Mark R. Woodford, Avgi Andreou, Masaya Baba, Irma van de Beek, Chiara Di Malta, Iris Glykofridis, Hannah Grimes, Elizabeth P. Henske, Othon Iliopoulos, Masatoshi Kurihara, Romain Lazor, W. Marston Linehan, Kenki Matsumoto, Stefan J. Marciniak, Yukiko Namba, Arnim Pause, Neil Rajan, Anindita Ray, Laura S. Schmidt, Wei Shi, Ortrud K. Steinlein, Julia Thierauf, Roberto Zoncu, Anna Webb,  and Mehdi Mollapour
173-181
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Corrections

Correction: Musashi2 promotes the development and progression of pancreatic cancer by down-regulating Numb protein

Correction: Musashi2 promotes the development and progression of pancreatic cancer by down-regulating Numb protein

https://doi.org/10.18632/oncotarget.28157

Weiwei Sheng, Ming Dong, Chuanping Chen, Yang Li, Qingfeng Liu,  and Qi Dong
182-182
Correction  |  PDF  |  How to cite

Research Papers

Influence of nutrition on stage-stratified survival in gastric cancer patients with postoperative complications

Influence of nutrition on stage-stratified survival in gastric cancer patients with postoperative complications

https://doi.org/10.18632/oncotarget.28179

Noriyuki Hirahara, Takeshi Matsubara, Shunsuke Kaji, Yuki Uchida, Ryoji Hyakudomi, Tetsu Yamamoto, Kiyoe Takai, Yohei Sasaki, Koki Kawakami,  and Yoshitsugu Tajima
183-197
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Research Papers

Common cancer treatments targeting DNA double strand breaks affect long-term memory and relate to immediate early gene expression in a sex-dependent manner

Common cancer treatments targeting DNA double strand breaks affect long-term memory and relate to immediate early gene expression in a sex-dependent manner

https://doi.org/10.18632/oncotarget.28180

Sydney Weber Boutros, Destine Krenik, Sarah Holden, Vivek K. Unni,  and Jacob Raber
198-213
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Podcast  |  Order a Reprint

Research Papers

Plasma biomarkers reflecting high oxidative stress in the prediction of myocardial injury due to anthracycline chemotherapy and the effect of carvedilol: insights from the CECCY Trial

Plasma biomarkers reflecting high oxidative stress in the prediction of myocardial injury due to anthracycline chemotherapy and the effect of carvedilol: insights from the CECCY Trial

https://doi.org/10.18632/oncotarget.28182

Mauro Rogério de Barros Wanderley Jr., Mônica Samuel Ávila, Miguel Morita Fernandes-Silva, Fátima das Dores Cruz, Sara Michelly Gonçalves Brandão, Vagner Oliveira Carvalho Rigaud, Ludhmila Abrahão Hajjar, Roberto Kalil Filho, Edécio Cunha-Neto, Edimar Alcides Bocchi,  and Silvia Moreira Ayub-Ferreira
214-223
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Research Papers

Impact of the glutathione synthesis pathway on sulfasalazine-treated endometrial cancer

Impact of the glutathione synthesis pathway on sulfasalazine-treated endometrial cancer

https://doi.org/10.18632/oncotarget.28185

Kanako Sendo, Manabu Seino, Tsuyoshi Ohta,  and Satoru Nagase
224-236
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Research Papers

Exploring the synergistic effects of cabozantinib and a programmed cell death protein 1 inhibitor in metastatic renal cell carcinoma with machine learning

Exploring the synergistic effects of cabozantinib and a programmed cell death protein 1 inhibitor in metastatic renal cell carcinoma with machine learning

https://doi.org/10.18632/oncotarget.28183

Ignacio Durán, Daniel Castellano, Javier Puente, Lidia Martín-Couce, Esther Bello, Urbano Anido, José Manuel Mas,  and Luis Costa
237-256
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Research Papers

Real-world survival analysis by tumor mutational burden in non-small cell lung cancer: a multisite U.S. study

Real-world survival analysis by tumor mutational burden in non-small cell lung cancer: a multisite U.S. study

https://doi.org/10.18632/oncotarget.28178

Connor Willis, Hillevi Bauer, Trang H. Au, Jyothi Menon, Sudhir Unni, Dao Tran, Zachary Rivers, Wallace Akerley, Matthew B. Schabath, Firas Badin, Ashley Sekhon, Malini Patel, Bing Xia, Beth Gustafson, John L. Villano, John-Michael Thomas, Solomon J. Lubinga, Michael A. Cantrell, Diana Brixner,  and David Stenehjem
257-270

Corrections

Correction: The attenuated hepatocellular carcinoma-specific Listeria vaccine Lmdd-MPFG prevents tumor occurrence through immune regulation of dendritic cells

Correction: The attenuated hepatocellular carcinoma-specific Listeria vaccine Lmdd-MPFG prevents tumor occurrence through immune regulation of dendritic cells

https://doi.org/10.18632/oncotarget.28154

Xin Wan, Ci Cheng, Zhe Lin, Runqiu Jiang, Wei Zhao, Xin Yan, Junwei Tang, Kun Yao, Beicheng Sun,  and Yun Chen
271-272
Correction  |  PDF  |  How to cite

Research Papers

Positive predictive value of ERBB2 copy number gain by tissue or circulating tumor DNA next-generation sequencing across advanced cancers

Positive predictive value of ERBB2 copy number gain by tissue or circulating tumor DNA next-generation sequencing across advanced cancers

https://doi.org/10.18632/oncotarget.28188

Ami N. Shah, Ashwin Sunderraj, Brian Finkelman, Sharlene H. See, Andrew A. Davis, Lorenzo Gerratana, Firas Wehbe, Neelima Katam, Deva Mahalingam, William J. Gradishar, Amir Behdad, Luis Blanco,  and Massimo Cristofanilli
273-280
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Research Papers

GZ17-6.02 and axitinib interact to kill renal carcinoma cells

GZ17-6.02 and axitinib interact to kill renal carcinoma cells

https://doi.org/10.18632/oncotarget.28189

Laurence Booth, Cameron West, Robert P. Moore, Daniel Von Hoff,  and Paul Dent
281-290
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Research Papers

PACER lncRNA regulates COX-2 expression in lung cancer cells

PACER lncRNA regulates COX-2 expression in lung cancer cells

https://doi.org/10.18632/oncotarget.28190

Samuel Z. Desind, Joseph R. Iacona, Christina Y. Yu, Antonina Mitrofanova,  and Carol S. Lutz
291-306

Research Papers

Antitumor effect of isoquercetin on tissue vasohibin expression and colon cancer vasculature

Antitumor effect of isoquercetin on tissue vasohibin expression and colon cancer vasculature

https://doi.org/10.18632/oncotarget.28181

Daniel de Castilho da Silva, Guilherme Di Camillo Orfali, Maycon Giovani Santana, Jessica Kaoru Yamamoto Palma, Isabella Ramos de Oliveira Assunção, Isadora Moraes Marchesi, Ana Yoshie Kitagawa Grizotto, Natália Peres Martinez, Simone Felliti, José Aires Pereira,  and Denise Gonçalves Priolli
307-318
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Research Papers

ABT199/venetoclax potentiates the cytotoxicity of alkylating agents and fludarabine in acute myeloid leukemia cells

ABT199/venetoclax potentiates the cytotoxicity of alkylating agents and fludarabine in acute myeloid leukemia cells

https://doi.org/10.18632/oncotarget.28193

Benigno C. Valdez, David Murray, Bin Yuan, Yago Nieto, Uday Popat,  and Borje S. Andersson
319-330
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Podcast  |  Order a Reprint

Corrections

Correction: 2’-Hydroxyflavanone effectively targets RLIP76-mediated drug transport and regulates critical signaling networks in breast cancer

Correction: 2’-Hydroxyflavanone effectively targets RLIP76-mediated drug transport and regulates critical signaling networks in breast cancer

https://doi.org/10.18632/oncotarget.28199

Lokesh Dalasanur Nagaprashantha, Jyotsana Singhal, Hongzhi Li, Charles Warden, Xueli Liu, David Horne, Sanjay Awasthi, Ravi Salgia,  and Sharad S. Singhal
331-331
Correction  |  PDF  |  How to cite

Research Papers

Etoposide-induced DNA damage is increased in p53 mutants: identification of ATR and other genes that influence effects of p53 mutations on Top2-induced cytotoxicity

Etoposide-induced DNA damage is increased in p53 mutants: identification of ATR and other genes that influence effects of p53 mutations on Top2-induced cytotoxicity

https://doi.org/10.18632/oncotarget.28195

Daniel Menendez, Jay R. Anand, Carri C. Murphy, Whitney J. Bell, Jiaqi Fu, Nadia Slepushkina, Eugen Buehler, Scott E. Martin, Madhu Lal-Nag, John L. Nitiss,  and Michael A. Resnick
332-346
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Research Papers

Telomere shortening accelerates tumor initiation in the L2-IL1B mouse model of Barrett esophagus and emerges as a possible biomarker

Telomere shortening accelerates tumor initiation in the L2-IL1B mouse model of Barrett esophagus and emerges as a possible biomarker

https://doi.org/10.18632/oncotarget.28198

Vincenz Sahm, Carlo Maurer, Theresa Baumeister, Akanksha Anand, Julia Strangmann, Roland M. Schmid, Timothy C. Wang,  and Michael Quante
347-359
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Research Papers

A comparison of 64Cu-labeled bi-terminally PEGylated A20FMDV2 peptides targeting integrin ανβ6

A comparison of 64Cu-labeled bi-terminally PEGylated A20FMDV2 peptides targeting integrin ανβ6

https://doi.org/10.18632/oncotarget.28197

Truc T. Huynh, Sreeja Sreekumar, Cedric Mpoy,  and Buck E. Rogers
360-372
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Research Papers

NOTCH1 PEST domain variants are responsive to standard of care treatments despite distinct transformative properties in a breast cancer model

NOTCH1 PEST domain variants are responsive to standard of care treatments despite distinct transformative properties in a breast cancer model

https://doi.org/10.18632/oncotarget.28200

Karen Cravero, Morgan V. Pantone, Dong Ho Shin, Riley Bergman, Rory Cochran, David Chu, Daniel J. Zabransky, Swathi Karthikeyan, Ian G. Waters, Natasha Hunter, D. Marc Rosen, Kelly Kyker-Snowman, W. Brian Dalton, Berry Button, Dan Shinn, Hong Yuen Wong, Joshua Donaldson, Paula J. Hurley, Sarah Croessmann,  and Ben Ho Park
373-386
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Research Papers

Metanephric adenoma: molecular study and review of the literature

Metanephric adenoma: molecular study and review of the literature

https://doi.org/10.18632/oncotarget.28192

Enrique Rodríguez-Zarco, Jesús Machuca-Aguado, Laura Macías-García, Ana Vallejo-Benítez,  and Juan José Ríos-Martín
387-392
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Reviews

The role of IGF-pathway biomarkers in determining risks, screening, and prognosis in lung cancer

The role of IGF-pathway biomarkers in determining risks, screening, and prognosis in lung cancer

https://doi.org/10.18632/oncotarget.28202

Alexander W. Pohlman, Hita Moudgalya, Lia Jordano, Gabriela C. Lobato, David Gerard, Michael J. Liptay, Christopher W. Seder,  and Jeffrey A. Borgia
393-407

Reviews

The long winding road to the safer glucocorticoid receptor (GR) targeting therapies

The long winding road to the safer glucocorticoid receptor (GR) targeting therapies

https://doi.org/10.18632/oncotarget.28191

Ekaterina A. Lesovaya, Daria Chudakova, Gleb Baida, Ekaterina M. Zhidkova, Kirill I. Kirsanov, Marianna G. Yakubovskaya,  and Irina V. Budunova
408-424
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Corrections

Correction: IL-17A weakens the antitumor immunity by inhibiting apoptosis of MDSCs in Lewis lung carcinoma bearing mice

Correction: IL-17A weakens the antitumor immunity by inhibiting apoptosis of MDSCs in Lewis lung carcinoma bearing mice

https://doi.org/10.18632/oncotarget.28052

Juan Wang, Yue Zhang, Kai Yin, Peiqi Xu, Jie Tian, Jie Ma, Xinyu Tian, Yungang Wang, Xinyi Tang, Huaxi Xu,  and Shengjun Wang
425-425
Correction  |  PDF  |  How to cite

Research Papers

A liquid fraction of extracellular matrix inhibits glioma cell viability in vitro and in vivo

A liquid fraction of extracellular matrix inhibits glioma cell viability in vitro and in vivo

https://doi.org/10.18632/oncotarget.28203

Mark H. Murdock, George S. Hussey, Jordan T. Chang, Ryan C. Hill, David G. Nascari, Aparna V. Rao, Kirk C. Hansen, Lesley M. Foley, T. Kevin Hitchens, Nduka M. Amankulor,  and Stephen F. Badylak
426-438
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Research Papers

Impact of combining vitamin C with radiation therapy in human breast cancer: does it matter?

Impact of combining vitamin C with radiation therapy in human breast cancer: does it matter?

https://doi.org/10.18632/oncotarget.28204

Somayeh Khazaei, Linn Nilsson, Gabriel Adrian, Helga Tryggvadottir, Elise Konradsson, Signe Borgquist, Karolin Isaksson, Crister Ceberg,  and Helena Jernström
439-453

Commentaries

Defining the mechanisms underlying cyclin dependent kinase control of HIF-1α

Defining the mechanisms underlying cyclin dependent kinase control of HIF-1α

https://doi.org/10.18632/oncotarget.28208

Noel A. Warfel
454-455
PDF  |  Full Text  |  How to cite  |  Order a Reprint

Reviews

Adjuvant osimertinib treatment in patients with early stage NSCLC (IB-IIIA): pathological pathway adaptations

Adjuvant osimertinib treatment in patients with early stage NSCLC (IB-IIIA): pathological pathway adaptations

https://doi.org/10.18632/oncotarget.28210

Antonio Marchetti, Fiamma Buttitta,  and Emanuela D’Angelo
456-463

Research Papers

Sequencing of BRCA1/2-alterations using NGS-based technology: annotation as a challenge

Sequencing of BRCA1/2-alterations using NGS-based technology: annotation as a challenge

https://doi.org/10.18632/oncotarget.28213

Silvana Ebner, Ria Winkelmann, Saskia Martin, Jens Köllermann, Peter J. Wild,  and Melanie Demes
464-475
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Research Papers

An investigation on [5 fluorouracil and epigallocatechin-3-gallate] complex activity on HT-29 cell death and its stability in gastrointestinal fluid

An investigation on [5 fluorouracil and epigallocatechin-3-gallate] complex activity on HT-29 cell death and its stability in gastrointestinal fluid

https://doi.org/10.18632/oncotarget.28207

Laura Moracci, Francesca Sensi, Andrea Biccari, Sara Crotti, Elisa Gaio, Federico Benetti, Pietro Traldi, Salvatore Pucciarelli,  and Marco Agostini
476-489
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Research Papers

Transplantation of autologous bone marrow pre-loaded ex vivo with oncolytic myxoma virus is efficacious against drug-resistant Vk*MYC mouse myeloma

Transplantation of autologous bone marrow pre-loaded ex vivo with oncolytic myxoma virus is efficacious against drug-resistant Vk*MYC mouse myeloma

https://doi.org/10.18632/oncotarget.28205

Nancy Y. Villa, Masmudur M. Rahman, Joseph Mamola, Meaghen E. Sharik, Ana Lemos de Matos, Jacquelyn Kilbourne, Kenneth Lowe, Juliane Daggett-Vondras, Julia D'Isabella, Elizabeth Goras, Marta Chesi, P. Leif Bergsagel,  and Grant McFadden
490-504
Abstract  |  PDF  |  Full Text  |  How to cite  |  Podcast  |  Order a Reprint

Corrections

Correction: Human astrocytes secrete IL-6 to promote glioma migration and invasion through upregulation of cytomembrane MMP14

Correction: Human astrocytes secrete IL-6 to promote glioma migration and invasion through upregulation of cytomembrane MMP14

https://doi.org/10.18632/oncotarget.28211

Weiliang Chen, Tongliang Xia, Donghai Wang, Bin Huang, Peng Zhao, Jian Wang, Xun Qu,  and Xingang Li
505-506
Correction  |  PDF  |  How to cite

Corrections

Correction: Tumor-suppressive microRNA-218 inhibits tumor angiogenesis via targeting the mTOR component RICTOR in prostate cancer

Correction: Tumor-suppressive microRNA-218 inhibits tumor angiogenesis via targeting the mTOR component RICTOR in prostate cancer

https://doi.org/10.18632/oncotarget.28206

Bing Guan, Kaijie Wu, Jin Zeng, Shan Xu, Lijun Mu, Yang Gao, Ke Wang, Zhenkun Ma, Juanhua Tian, Qi Shi, Peng Guo, Xinyang Wang, Dalin He,  and Yuefeng Du
507-507
Correction  |  PDF  |  How to cite

Research Papers

Cytogenetic and molecular analyses of 291 gastrointestinal stromal tumors: site-specific cytogenetic evolution as evidence of pathogenetic heterogeneity

Cytogenetic and molecular analyses of 291 gastrointestinal stromal tumors: site-specific cytogenetic evolution as evidence of pathogenetic heterogeneity

https://doi.org/10.18632/oncotarget.28209

Ludmila Gorunova, Kjetil Boye, Ioannis Panagopoulos, Jeanne-Marie Berner, Bodil Bjerkehagen, Ivar Hompland, Ingvild Lobmaier, Toto Hølmebakk, Tarjei S. Hveem, Sverre Heim,  and Francesca Micci
508-517
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Corrections

Correction: Clinical significance and effect of AEG-1 on the proliferation, invasion, and migration of NSCLC: a study based on immunohistochemistry, TCGA, bioinformatics, in vitro and in vivo verification

Correction: Clinical significance and effect of AEG-1 on the proliferation, invasion, and migration of NSCLC: a study based on immunohistochemistry, TCGA, bioinformatics, in vitro and in vivo verification

https://doi.org/10.18632/oncotarget.28212

Yu Zhang, Zu-Yun Li, Xin-Xi Hou, Xiao Wang, Yi-Huan Luo, Yan-Ping Ying,  and Gang Chen
518-520
Correction  |  PDF  |  How to cite

Research Papers

Correlation of nuclear pIGF-1R/IGF-1R and YAP/TAZ in a tissue microarray with outcomes in osteosarcoma patients

Correlation of nuclear pIGF-1R/IGF-1R and YAP/TAZ in a tissue microarray with outcomes in osteosarcoma patients

https://doi.org/10.18632/oncotarget.28215

Eric R. Molina, Letitia K. Chim, Salah-Eddine Lamhamedi-Cherradi, Sana Mohiuddin, David McCall, Branko Cuglievan, Sandhya Krishnan, Robert W. Porter, Davis R. Ingram, Wei-Lien Wang, Alexander J. Lazar, David W. Scott, Danh D. Truong, Najat C. Daw, Joseph A. Ludwig,  and Antonios G. Mikos
521-533
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Podcast  |  Order a Reprint

Research Papers

MYH9 binds to dNTPs via deoxyribose moiety and plays an important role in DNA synthesis

MYH9 binds to dNTPs via deoxyribose moiety and plays an important role in DNA synthesis

https://doi.org/10.18632/oncotarget.28219

Pratima Nangia-Makker, Malathy P.V. Shekhar, Victor Hogan, Vitaly Balan,  and Avraham Raz
534-550
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Retraction

Retraction: Transcriptome analysis reveals a role for the endothelial ANP-GC-A signaling in interfering with pre-metastatic niche formation by solid cancers

Retraction: Transcriptome analysis reveals a role for the endothelial ANP-GC-A signaling in interfering with pre-metastatic niche formation by solid cancers

https://doi.org/10.18632/oncotarget.28223

Takashi Nojiri, Miki Arai, Yutaka Suzuki, Motofumi Kumazoe, Takeshi Tokudome, Koichi Miura, Jun Hino, Hiroshi Hosoda, Mikiya Miyazato, Meinoshin Okumura, Shinpei Kawaoka,  and Kenji Kangawa
551-552
Retraction  |  PDF  |  How to cite

Reviews

Patient-derived tumor models are attractive tools to repurpose drugs for ovarian cancer treatment: pre-clinical updates

Patient-derived tumor models are attractive tools to repurpose drugs for ovarian cancer treatment: pre-clinical updates

https://doi.org/10.18632/oncotarget.28220

Magdalena Cybula,  and Magdalena Bieniasz
553-575
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Case Reports

Resolution of radiation necrosis with bevacizumab following radiation therapy for primary CNS lymphoma

Resolution of radiation necrosis with bevacizumab following radiation therapy for primary CNS lymphoma

https://doi.org/10.18632/oncotarget.28222

Eugene J. Vaios, Kristen A. Batich, Anne F. Buckley, Anastasie Dunn-Pirio, Mallika P. Patel, John P. Kirkpatrick, Ranjit Goudar,  and Katherine B. Peters
576-582
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Corrections

Correction: Silencing of CXCR4 sensitizes triple-negative breast cancer cells to cisplatin

Correction: Silencing of CXCR4 sensitizes triple-negative breast cancer cells to cisplatin

https://doi.org/10.18632/oncotarget.28109

Sixian Liang, Xun Peng, Xiaoli Li, Ping Yang, Linhao Xie, Yaochen Li, Caiwen Du,  and Guojun Zhang
583-584
Correction  |  PDF  |  How to cite

Corrections

Correction: Lysosomal sequestration of hydrophobic weak base chemotherapeutics triggers lysosomal biogenesis and lysosome-dependent cancer multidrug resistance

Correction: Lysosomal sequestration of hydrophobic weak base chemotherapeutics triggers lysosomal biogenesis and lysosome-dependent cancer multidrug resistance

https://doi.org/10.18632/oncotarget.28110

Benny Zhitomirsky,  and Yehuda G. Assaraf
585-586
Correction  |  PDF  |  How to cite

Research Papers

Role of the prorenin receptor in endometrial cancer cell growth

Role of the prorenin receptor in endometrial cancer cell growth

https://doi.org/10.18632/oncotarget.28224

Jacinta H. Martin, Riazuddin Mohammed, Sarah J. Delforce, David A. Skerrett-Byrne, Celine Corbisier de Meaultsart, Juhura G. Almazi, Andrew N. Stephens, Nicole M. Verrills, Evdokia Dimitriadis, Yu Wang, Eugenie R. Lumbers,  and Kirsty G. Pringle
587-599
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Research Papers

A novel group of genes that cause endocrine resistance in breast cancer identified by dynamic gene expression analysis

A novel group of genes that cause endocrine resistance in breast cancer identified by dynamic gene expression analysis

https://doi.org/10.18632/oncotarget.28225

Arvand Asghari, Katherine Wall, Michael Gill, Natascha Del Vecchio, Farnaz Allahbakhsh, Jacky Wu, Nan Deng, W. Jim Zheng, Hulin Wu, Michihisa Umetani,  and Vahed Maroufy
600-613

Corrections

Correction: MicroRNA-613 inhibits cell growth, migration and invasion of papillary thyroid carcinoma by regulating SphK2

Correction: MicroRNA-613 inhibits cell growth, migration and invasion of papillary thyroid carcinoma by regulating SphK2

https://doi.org/10.18632/oncotarget.28155

Wangwang Qiu, Zhili Yang, Youben Fan,  and Qi Zheng
614-614
Correction  |  PDF  |  How to cite

Research Papers

Loss of DRO1/CCDC80 in the tumor microenvironment promotes carcinogenesis

Loss of DRO1/CCDC80 in the tumor microenvironment promotes carcinogenesis

https://doi.org/10.18632/oncotarget.28084

Jessica I. Christian, Agnieszka Pastula, Andreas Herbst, Jens Neumann, Maximilian K. Marschall, Andrea Ofner, Heike Zierahn, Marlon R. Schneider, Eckhard Wolf, Michael Quante,  and Frank T. Kolligs
615-627
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint

Research Papers

Bladder cancer survival in patients with NOD2 or CDKN2A variants

Bladder cancer survival in patients with NOD2 or CDKN2A variants

https://doi.org/10.18632/oncotarget.28226

Elżbieta Złowocka-Perłowska, Thierry van de Wetering, Aleksandra Tołoczko-Grabarek, Rodney J. Scott,  and Jan Lubiński
628-640
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Corrections

Correction: MR imaging biomarkers evaluating vascular normalization window after anti-vessel treatment

Correction: MR imaging biomarkers evaluating vascular normalization window after anti-vessel treatment

https://doi.org/10.18632/oncotarget.28217

Jun Yang, Chengde Liao, Yifan Liu, Guangjun Yang, Tengfei Ke, Yingying Ding,  and Qinqing Li
641-641
Correction  |  PDF  |  How to cite

Research Papers

Combined treatment with niclosamide and camptothecin enhances anticancer effect in U87 MG human glioblastoma cells

Combined treatment with niclosamide and camptothecin enhances anticancer effect in U87 MG human glioblastoma cells

https://doi.org/10.18632/oncotarget.28227

Laura Valdez, Benxu Cheng, Daniela Gonzalez, Reanna Rodriguez, Paola Campano, Andrew Tsin,  and Xiaoqian Fang
642-658
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Research Papers

Proteomic analysis reveals dual requirement for Grb2 and PLCγ1 interactions for BCR-FGFR1-Driven 8p11 cell proliferation

Proteomic analysis reveals dual requirement for Grb2 and PLCγ1 interactions for BCR-FGFR1-Driven 8p11 cell proliferation

https://doi.org/10.18632/oncotarget.28228

Malalage N. Peiris, April N. Meyer, Dalida Warda, Alexandre Rosa Campos,  and Daniel J. Donoghue
659-676
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Research Papers

Tazemetostat in relapsed/refractory follicular lymphoma: a propensity score–matched analysis of E7438-G000-101 trial outcomes

Tazemetostat in relapsed/refractory follicular lymphoma: a propensity score–matched analysis of E7438-G000-101 trial outcomes

https://doi.org/10.18632/oncotarget.28229

David G. Proudman, Deepshekhar Gupta, Dave Nellesen, Jay Yang, Beth A. Kamp, Khalid Mamlouk,  and Bruce D. Cheson
677-683
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Corrections

Correction: Silence of cancer susceptibility candidate 9 inhibits gastric cancer and reverses chemoresistance

Correction: Silence of cancer susceptibility candidate 9 inhibits gastric cancer and reverses chemoresistance

https://doi.org/10.18632/oncotarget.27523

Chao Shang, Lin Sun, Jiale Zhang, Bochao Zhao, Xiuxiu Chen, Huimian Xu,  and Baojun Huang
684-685
Correction  |  PDF  |  How to cite

Research Papers

Response to immunotherapy in KRAS G12C mutated NSCLC: a single-centre retrospective observational study

Response to immunotherapy in KRAS G12C mutated NSCLC: a single-centre retrospective observational study

https://doi.org/10.18632/oncotarget.28230

Carolina Sciortino, Valentina Viglialoro, Massimo Nucci, Mariam Grazia Polito, Enrico Cortesi, Alain Gelibter, Paola Gazzaniga, Chiara Nicolazzo, Marco Siringo,  and Salvatore Caponnetto
686-693
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Corrections

Correction: LncRNA AFAP1-AS1 promotes growth and metastasis of cholangiocarcinoma cells

Correction: LncRNA AFAP1-AS1 promotes growth and metastasis of cholangiocarcinoma cells

https://doi.org/10.18632/oncotarget.28216

Xiuhui Shi, Hang Zhang, Min Wang, Xiaodong Xu, Yan Zhao, Ruizhi He, Min Zhang, Min Zhou, Xu Li, Feng Peng, Chengjian Shi, Ming Shen, Xin Wang, Xingjun Guo,  and Renyi Qin
694
Correction  |  PDF  |  How to cite

Research Papers

CancerOmicsNet: a multi-omics network-based approach to anti-cancer drug profiling

CancerOmicsNet: a multi-omics network-based approach to anti-cancer drug profiling

https://doi.org/10.18632/oncotarget.28234

Limeng Pu, Manali Singha, Jagannathan Ramanujam,  and Michal Brylinski
695-706
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release  |  Order a Reprint

Research Papers

NF-κB over-activation portends improved outcomes in HPV-associated head and neck cancer

NF-κB over-activation portends improved outcomes in HPV-associated head and neck cancer

https://doi.org/10.18632/oncotarget.28232

Travis P. Schrank, Andrew C. Prince, Tejas Sathe, Xiaowei Wang, Xinyi Liu, Damir T. Alzhanov, Barbara Burtness, Albert S. Baldwin, Wendell G. Yarbrough,  and Natalia Issaeva
707-722
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint

Corrections

Correction: Mouse Sirt3 promotes autophagy in AngII-induced myocardial hypertrophy through the deacetylation of FoxO1

Correction: Mouse Sirt3 promotes autophagy in AngII-induced myocardial hypertrophy through the deacetylation of FoxO1

https://doi.org/10.18632/oncotarget.28146

Jingyuan Li, Tongshuai Chen, Ming Xiao, Na Li, Shujian Wang, Hongyan Su, Xiaobin Guo, Hui Liu, Fangying Yan, Yi Yang, Yun Zhang,  and Peili Bu
723-724
Correction  |  PDF  |  How to cite

Research Papers

Deciphering miR-520c-3p as a probable target for immunometabolism in non-small cell lung cancer using systems biology approach

Deciphering miR-520c-3p as a probable target for immunometabolism in non-small cell lung cancer using systems biology approach

https://doi.org/10.18632/oncotarget.28233

Pooja Gulhane, Prajakta Nimsarkar, Komal Kharat,  and Shailza Singh
725-746
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Research Papers

HOXB9 mediates resistance to chemotherapy and patient outcomes through the TGFβ pathway in pancreatic cancer

HOXB9 mediates resistance to chemotherapy and patient outcomes through the TGFβ pathway in pancreatic cancer

https://doi.org/10.18632/oncotarget.28235

Naokazu Chiba, Shigeto Ochiai, Takahiro Gunji, Toshimichi Kobayashi, Toru Sano, Koichi Tomita,  and Shigeyuki Kawachi
747-754
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Corrections

Correction: Analysis of miRNA profiles identified miR-196a as a crucial mediator of aberrant PI3K/AKT signaling in lung cancer cells

Correction: Analysis of miRNA profiles identified miR-196a as a crucial mediator of aberrant PI3K/AKT signaling in lung cancer cells

https://doi.org/10.18632/oncotarget.28237

Ilaria Guerriero, Daniela D’Angelo, Pierlorenzo Pallante, Mafalda Santos, Marianna Scrima, Donatella Malanga, Carmela De Marco, Maria Ravo, Alessandro Weisz, Carmelo Laudanna, Michele Ceccarelli, Geppino Falco, Antonia Rizzuto,  and Giuseppe Viglietto
755-755
Correction  |  PDF  |  How to cite

Research Papers

Identification of lung cancer drivers by comparison of the observed and the expected numbers of missense and nonsense mutations in individual human genes

Identification of lung cancer drivers by comparison of the observed and the expected numbers of missense and nonsense mutations in individual human genes

https://doi.org/10.18632/oncotarget.28231

Olga Y. Gorlova, Marek Kimmel, Spiridon Tsavachidis, Christopher I. Amos,  and Ivan P. Gorlov
756-767
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Reviews

Targeting lipid metabolism in the treatment of ovarian cancer

Targeting lipid metabolism in the treatment of ovarian cancer

https://doi.org/10.18632/oncotarget.28241

Saliha Chaudhry, Stefani N. Thomas,  and Glenn E. Simmons Jr.
768-783
Abstract  |  PDF  |  Full Text  |  How to cite  |  Video Interview  |  Order a Reprint

Corrections

Correction: YAP promotes tumorigenesis and cisplatin resistance in neuroblastoma

Correction: YAP promotes tumorigenesis and cisplatin resistance in neuroblastoma

https://doi.org/10.18632/oncotarget.28138

Chao Yang, Juan Tan, Jun Zhu, Shan Wang,  and Guanghui Wei
784-784
Correction  |  PDF  |  How to cite

Research Papers

IL-33 promotes gastric tumour growth in concert with activation and recruitment of inflammatory myeloid cells

IL-33 promotes gastric tumour growth in concert with activation and recruitment of inflammatory myeloid cells

https://doi.org/10.18632/oncotarget.28238

Chau P. Tran, Michelle Scurr, Louise O’Connor, Jon N. Buzzelli, Garrett Z. Ng, Sharleen Chung Nien Chin, Lincon A. Stamp, Toshinari Minamoto, Andrew S. Giraud, Louise M. Judd, Philip Sutton,  and Trevelyan R. Menheniott
785-799
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Research Papers

Are anaplastic lymphoma kinase (ALK) and O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation driver biomarkers of pulmonary neuroendocrine tumors (NETs) and carcinomas (NECs)?

Are anaplastic lymphoma kinase (ALK) and O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation driver biomarkers of pulmonary neuroendocrine tumors (NETs) and carcinomas (NECs)?

https://doi.org/10.18632/oncotarget.28240

Birgitta Hiddinga, Karen Zwaenepoel, Annelies Janssens, Jan Van Meerbeeck,  and Patrick Pauwels
800-809
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Corrections

Correction: Neferine inhibits proliferation and collagen synthesis induced by high glucose in cardiac fibroblasts and reduces cardiac fibrosis in diabetic mice

Correction: Neferine inhibits proliferation and collagen synthesis induced by high glucose in cardiac fibroblasts and reduces cardiac fibrosis in diabetic mice

https://doi.org/10.18632/oncotarget.28214

Xue Liu, Xiuhui Song, Jianjun Lu, Xueying Chen, Ershun Liang, Xiaoqiong Liu, Mingxiang Zhang, Yun Zhang, Zhanhui Du,  and Yuxia Zhao
810-811
Correction  |  PDF  |  How to cite

Research Papers

Alectinib after failure to crizotinib in patients with ALK-positive non-small cell lung cancer: results from the Spanish early access program

Alectinib after failure to crizotinib in patients with ALK-positive non-small cell lung cancer: results from the Spanish early access program

https://doi.org/10.18632/oncotarget.28244

Reyes Bernabé-Caro, Pilar Garrido, Rosario García-Campelo, Ramón Palmero, Ángel Artal, Cristina Bayona, Delvys Rodríguez-Abreu, Marta López-Brea, Alfredo Paredes, David Vicente, José Miguel Sánchez Torres, Margarita Majem, Pilar Diz, Rocío Gordo, Margarita Coca,  and Javier de Castro
812-827
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Reviews

Early-onset pancreatic cancer: a review of molecular mechanisms, management, and survival

Early-onset pancreatic cancer: a review of molecular mechanisms, management, and survival

https://doi.org/10.18632/oncotarget.28242

Mark B. Ulanja, Alastair E. Moody, Bryce D. Beutler, Daniel Antwi-Amoabeng, Ganiyu A. Rahman,  and Olatunji B. Alese
828-841
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Retraction

Retraction: MicroRNA-497 inhibits thyroid cancer tumor growth and invasion by suppressing BDNF

Retraction: MicroRNA-497 inhibits thyroid cancer tumor growth and invasion by suppressing BDNF

https://doi.org/10.18632/oncotarget.28248

Peisong Wang, Xianying Meng, Yan Huang, Zhi Lv, Jia Liu, Guimin Wang, Wei Meng, Shuai Xue, Qiang Zhang, Pengju Zhang,  and Guang Chen
842-842
Retraction  |  PDF  |  How to cite

Research Papers

Role of germline variants in the metastasis of breast carcinomas

Role of germline variants in the metastasis of breast carcinomas

https://doi.org/10.18632/oncotarget.28250

Ángela Santonja, Aurelio A. Moya-García, Nuria Ribelles, Begoña Jiménez-Rodríguez, Bella Pajares, Cristina E. Fernández-De Sousa, Elísabeth Pérez-Ruiz, María del Monte-Millán, Manuel Ruiz-Borrego, Juan de la Haba, Pedro Sánchez-Rovira, Atocha Romero, Anna González-Neira, Ana Lluch,  and Emilio Alba
843-862
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint

Retraction

Retraction: MicroRNA-218 inhibits proliferation and invasion in ovarian cancer by targeting Runx2

Retraction: MicroRNA-218 inhibits proliferation and invasion in ovarian cancer by targeting Runx2

https://doi.org/10.18632/oncotarget.28253

Na Li, Lufei Wang, Guangyun Tan, Zhiheng Guo, Lei Liu, Ming Yang,  and Jin He
863-863
Retraction  |  PDF  |  How to cite

Research Papers

Continuous treatment with abemaciclib leads to sustained and efficient inhibition of breast cancer cell proliferation

Continuous treatment with abemaciclib leads to sustained and efficient inhibition of breast cancer cell proliferation

https://doi.org/10.18632/oncotarget.28249

Raquel Torres-Guzmán, Maria Patricia Ganado, Cecilia Mur, Carlos Marugan, Carmen Baquero, Yanzhu Yang, Yi Zeng, Huimin Bian, Jian Du, Alfonso de Dios, Oscar Puig,  and María José Lallena
864-875
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint

Research Papers

Predicting cancer immunotherapy response from gut microbiomes using machine learning models

Predicting cancer immunotherapy response from gut microbiomes using machine learning models

https://doi.org/10.18632/oncotarget.28252

Hai Liang, Jay-Hyun Jo, Zhiwei Zhang, Margaret A. MacGibeny, Jungmin Han, Diana M. Proctor, Monica E. Taylor, You Che, Paul Juneau, Andrea B. Apolo, John A. McCulloch, Diwakar Davar, Hassane M. Zarour, Amiran K. Dzutsev, Isaac Brownell, Giorgio Trinchieri, James L. Gulley,  and Heidi H. Kong
876-889
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint

Research Papers

CUDC907, a dual phosphoinositide-3 kinase/histone deacetylase inhibitor, promotes apoptosis of NF2 Schwannoma cells

CUDC907, a dual phosphoinositide-3 kinase/histone deacetylase inhibitor, promotes apoptosis of NF2 Schwannoma cells

https://doi.org/10.18632/oncotarget.28254

Julianne Huegel, Christine T. Dinh, Maria Martinelli, Olena Bracho, Rosa Rosario, Haley Hardin, Michael Estivill, Anthony Griswold, Sakir Gultekin, Xue-Zhong Liu,  and Cristina Fernandez-Valle
890-904
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint

Corrections

Correction: Immunotherapy of ovarian cancer with a monoclonal antibody specific for the extracellular domain of anti-Müllerian hormone receptor II

Correction: Immunotherapy of ovarian cancer with a monoclonal antibody specific for the extracellular domain of anti-Müllerian hormone receptor II

https://doi.org/10.18632/oncotarget.28246

Suparna Mazumder, Valerie Swank, Anton A. Komar, Justin M. Johnson,  and Vincent K. Tuohy
905-906
Correction  |  PDF  |  How to cite

Research Papers

Chemoradiation-induced alteration of programmed death-ligand 1, CD8+ tumor-infiltrating lymphocytes and mucin expression in rectal cancer

Chemoradiation-induced alteration of programmed death-ligand 1, CD8+ tumor-infiltrating lymphocytes and mucin expression in rectal cancer

https://doi.org/10.18632/oncotarget.28255

Marina Baretti, Qingfeng Zhu, Wei Fu, Jeffrey Meyer, Hao Wang, Robert A. Anders,  and Nilofer S. Azad
907-917
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release  |  Order a Reprint

Research Papers

Diverse geroprotectors differently affect a mechanism linking cellular aging to cellular quiescence in budding yeast

Diverse geroprotectors differently affect a mechanism linking cellular aging to cellular quiescence in budding yeast

https://doi.org/10.18632/oncotarget.28256

Anna Leonov, Rachel Feldman, Amanda Piano, Anthony Arlia-Ciommo, Jennifer Anne Baratang Junio, Emmanuel Orfanos, Tala Tafakori, Vicky Lutchman, Karamat Mohammad, Sarah Elsaser, Sandra Orfali, Harshvardhan Rajen,  and Vladimir I. Titorenko
918-943
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Priority Research Papers

A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling

A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling

https://doi.org/10.18632/oncotarget.28261

Stephan J. Matissek, Mona Karbalivand, Weiguo Han, Ava Boutilier, Estefania Yzar-Garcia, Laura L. Kehoe, Devin Storm Gardner, Adam Hage, Krista Fleck, Vicki Jeffers, Ricardo Rajsbaum,  and Sherine F. Elsawa
944-959
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint

Research Papers

Glypican-3 (GPC3) is associated with MCPyV-negative status and impaired outcome in Merkel cell carcinoma

Glypican-3 (GPC3) is associated with MCPyV-negative status and impaired outcome in Merkel cell carcinoma

https://doi.org/10.18632/oncotarget.28260

Sujatha Muralidharan, Thibault Kervarrec, Glen J. Weiss,  and Mahtab Samimi
960-967
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint

Corrections

Correction: Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis

Correction: Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis

https://doi.org/10.18632/oncotarget.28104

Reza Bayat Mokhtari, Bessi Qorri, Narges Baluch, Angelo Sparaneo, Federico Pio Fabrizio, Lucia Anna Muscarella, Albina Tyker, Sushil Kumar, Hai-Ling Margaret Cheng, Myron R. Szewczuk, Bikul Das,  and Herman Yeger
968-969
Correction  |  PDF  |  How to cite

Research Papers

Kinase activity profiling in renal cell carcinoma, benign renal tissue and in response to four different tyrosine kinase inhibitors

Kinase activity profiling in renal cell carcinoma, benign renal tissue and in response to four different tyrosine kinase inhibitors

https://doi.org/10.18632/oncotarget.28257

Andliena Tahiri, Katarina Puco, Faris Naji, Vessela N. Kristensen, Glenny Cecilie Alfsen, Lorant Farkas, Frode S. Nilsen, Stig Müller, Jan Oldenburg,  and Jürgen Geisler
970-981
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint

Addendum

Addendum: A case report of androgen receptor inhibitor therapy in recurrent high-grade serous ovarian cancer

Addendum: A case report of androgen receptor inhibitor therapy in recurrent high-grade serous ovarian cancer

https://doi.org/10.18632/oncotarget.28262

Sewanti Limaye, Prashant Kumar, Ramya Pragya, Janani Sambath, Darshana Patil, Ajay Srinivasan, Sachin Apurva, Navin Srivastava, Sanket Patil, Revati Patil, Vineet Datta, Dadasaheb Akolkar,  and Rajan Datar
982-982
Addendum  |  PDF  |  How to cite

Addendum

Addendum: A case series of advanced renal cell carcinoma patients treated with neoadjuvant cabozantinib prior to cytoreductive nephrectomy within the phase 2 CABOPRE trial

Addendum: A case series of advanced renal cell carcinoma patients treated with neoadjuvant cabozantinib prior to cytoreductive nephrectomy within the phase 2 CABOPRE trial

https://doi.org/10.18632/oncotarget.28263

Guillermo de Velasco, Lucia Carril-Ajuria, Felix Guerrero-Ramos, Teresa Alonso-Gordoa, Juan F. Rodríguez-Moreno, Alberto Carretero, Maricruz Martin-Soberon, Federico de la Rosa-Kehrmann,  and Daniel Castellano
983-983
Addendum  |  PDF  |  How to cite

Addendum

Addendum: Standardized diagnostic algorithm for spitzoid lesions aids clinical decision-making and management: a case series from a Swiss reference center

Addendum: Standardized diagnostic algorithm for spitzoid lesions aids clinical decision-making and management: a case series from a Swiss reference center

https://doi.org/10.18632/oncotarget.28264

Marie-Luise Hilbers, Regula Brändli, Beda Mühleisen, Sandra N. Freiberger, Joanna Mangana,  and Reinhard Dummer
984-984
Addendum  |  PDF  |  How to cite

Addendum

Addendum: Immunotherapy in Xeroderma Pigmentosum: a case of advanced cutaneous squamous cell carcinoma treated with cemiplimab and a literature review

Addendum: Immunotherapy in Xeroderma Pigmentosum: a case of advanced cutaneous squamous cell carcinoma treated with cemiplimab and a literature review

https://doi.org/10.18632/oncotarget.28265

Marco Rubatto, Martina Merli, Gianluca Avallone, Andrea Agostini, Luca Mastorino, Virginia Caliendo, Amelia Barcellini, Viviana Vitolo, Francesca Valvo, Maria Teresa Fierro, Simone Ribero,  and Pietro Quaglino
985-985
Addendum  |  PDF  |  How to cite

Research Papers

Combined epigenetic and immunotherapy for blastic and classical mantle cell lymphoma

Combined epigenetic and immunotherapy for blastic and classical mantle cell lymphoma

https://doi.org/10.18632/oncotarget.28258

Francis R. LeBlanc, Zainul S. Hasanali, August Stuart, Sara Shimko, Kamal Sharma, Violetta V. Leshchenko, Samir Parekh, Haiqing Fu, Ya Zhang, Melvenia M. Martin, Mark Kester, Todd Fox, Jiangang Liao, Thomas P. Loughran, Juanita Evans, Jeffrey J. Pu, Stephen E. Spurgeon, Mirit I. Aladjem,  and Elliot M. Epner
986-1002
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Retraction

Retraction: MicroRNA-182 downregulates Wnt/β-catenin signaling, inhibits proliferation, and promotes apoptosis in human osteosarcoma cells by targeting HOXA9

Retraction: MicroRNA-182 downregulates Wnt/β-catenin signaling, inhibits proliferation, and promotes apoptosis in human osteosarcoma cells by targeting HOXA9

https://doi.org/10.18632/oncotarget.28269

Zi-Feng Zhang, Yong-Jian Wang, Shao-Hua Fan, Shi-Xin Du, Xue-Dong Li, Dong-Mei Wu, Jun Lu,  and Yuan-Lin Zheng
1003-1003
Retraction  |  PDF  |  How to cite

Research Papers

Targeted elastin-like polypeptide fusion protein for near-infrared imaging of human and canine urothelial carcinoma

Targeted elastin-like polypeptide fusion protein for near-infrared imaging of human and canine urothelial carcinoma

https://doi.org/10.18632/oncotarget.28271

Aayush Aayush, Saloni Darji, Deepika Dhawan, Alexander Enstrom, Meaghan M. Broman, Muhammad T. Idrees, Hristos Kaimakliotis, Timothy Ratliff, Deborah Knapp,  and David Thompson
1004-1016
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint

Editorial

An ABC transporter as a potential target against SHH-Medulloblastoma: From Benchtop to Bedside

An ABC transporter as a potential target against SHH-Medulloblastoma: From Benchtop to Bedside

https://doi.org/10.18632/oncotarget.28272

Jingwen Zhu, Joseph N. Miller,  and John D. Schuetz
1017-1019
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Research Papers

Prediction of recurrence free survival for esophageal cancer patients using a protein signature based risk model

Prediction of recurrence free survival for esophageal cancer patients using a protein signature based risk model

https://doi.org/10.18632/oncotarget.10656

Raghibul Hasan, Gunjan Srivastava, Akram Alyass, Rinu Sharma, Anoop Saraya, Tushar K. Chattopadhyay, Siddartha DattaGupta, Paul G. Walfish, Shyam S. Chauhan,  and Ranju Ralhan
1020-1032
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Retraction

Retraction: MicroRNA-433 inhibits oral squamous cell carcinoma cells by targeting FAK

Retraction: MicroRNA-433 inhibits oral squamous cell carcinoma cells by targeting FAK

https://doi.org/10.18632/oncotarget.28270

Yong-Jian Wang, Zi-Feng Zhang, Shao-Hua Fan, Juan Zhuang, Qun Shan, Xin-Rui Han, Xin Wen, Meng-Qiu Li, Bin Hu, Chun-Hui Sun, Bin Qiao, Qian Tao, Dong-Mei Wu, Jun Lu,  and Yuan-Lin Zheng
1033-1033
Retraction  |  PDF  |  How to cite

Research Papers

Site of analysis matters - Ongoing complete response to Nivolumab in a patient with HIV/HPV related metastatic anal cancer and MLH1 mutation

Site of analysis matters - Ongoing complete response to Nivolumab in a patient with HIV/HPV related metastatic anal cancer and MLH1 mutation

https://doi.org/10.18632/oncotarget.28274

Melanie Demes, Ursula Pession, Jan Jeroch, Falko Schulze, Katrin Eichler, Daniel Martin, Peter Wild,  and Oliver Waidmann
1034-1042
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release  |  Order a Reprint

Research Papers

Influence of high altitude on the expression of HIF-1 and on the prognosis of Ecuadorian patients with gastric adenocarcinoma

Influence of high altitude on the expression of HIF-1 and on the prognosis of Ecuadorian patients with gastric adenocarcinoma

https://doi.org/10.18632/oncotarget.28275

Edwin Cevallos Barrera, Edson Zangiacomi Martinez, Mariangela Ottoboni Brunaldi, Eduardo Antonio Donadi, Ajith Kumar Sankarankutty, Rafael Kemp,  and José Sebastiao dos Santos
1043-1053
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Research Papers

Targeting Krebs-cycle-deficient renal cell carcinoma with Poly ADP-ribose polymerase inhibitors and low-dose alkylating chemotherapy

Targeting Krebs-cycle-deficient renal cell carcinoma with Poly ADP-ribose polymerase inhibitors and low-dose alkylating chemotherapy

https://doi.org/10.18632/oncotarget.28273

Daiki Ueno, Juan C. Vasquez, Amrita Sule, Jiayu Liang, Jinny van Doorn, Ranjini Sundaram, Sam Friedman, Randy Caliliw, Shinji Ohtake, Xun Bao, Jing Li, Huihui Ye, Karla Boyd, Rong Rong Huang, Jack Dodson, Paul Boutros, Ranjit S. Bindra,  and Brian Shuch
1054-1067
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint

Corrections

Correction: Exploratory comparisons between different anti-mitotics in clinically-used drug combination in triple negative breast cancer

Correction: Exploratory comparisons between different anti-mitotics in clinically-used drug combination in triple negative breast cancer

https://doi.org/10.18632/oncotarget.28266

Bruna Cândido Guido, Douglas Cardoso Brandão, Ana Luisa Augusto Barbosa, Monique Jacob Xavier Vianna, Lucas Faro, Luciana Machado Ramos, Fabíola Nihi, Márcio Botelho de Castro, Brenno A.D. Neto, José Raimundo Corrêa,  and Sônia Nair Báo
1068-1068
Correction  |  PDF  |  How to cite

Research Papers

Genomic alterations predictive of poor clinical outcomes in pan-cancer

Genomic alterations predictive of poor clinical outcomes in pan-cancer

https://doi.org/10.18632/oncotarget.28276

Crystal S. Seldon, Karthik Meiyappan, Hannah Hoffman, Jimmy A. Guo, Neha Goel, William L. Hwang, Paul L. Nguyen, Brandon A. Mahal,  and Mohammed Alshalalfa
1069-1077
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint

Research Papers

Complementary CRISPR genome-wide genetic screens in PARP10-knockout and overexpressing cells identify synthetic interactions for PARP10-mediated cellular survival

Complementary CRISPR genome-wide genetic screens in PARP10-knockout and overexpressing cells identify synthetic interactions for PARP10-mediated cellular survival

https://doi.org/10.18632/oncotarget.28277

Jude B. Khatib, Emily M. Schleicher, Lindsey M. Jackson, Ashna Dhoonmoon, George-Lucian Moldovan,  and Claudia M. Nicolae
1078-1091
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Corrections

Correction: Influence of nutrition on stage-stratified survival in gastric cancer patients with postoperative complications

Correction: Influence of nutrition on stage-stratified survival in gastric cancer patients with postoperative complications

https://doi.org/10.18632/oncotarget.28243

Noriyuki Hirahara, Takeshi Matsubara, Shunsuke Kaji, Yuki Uchida, Ryoji Hyakudomi, Tetsu Yamamoto, Kiyoe Takai, Yohei Sasaki, Koki Kawakami,  and Yoshitsugu Tajima
1092-1093
Correction  |  PDF  |  How to cite

Research Papers

In vitro chemotherapy-associated muscle toxicity is attenuated with nutritional support, while treatment efficacy is retained

In vitro chemotherapy-associated muscle toxicity is attenuated with nutritional support, while treatment efficacy is retained

https://doi.org/10.18632/oncotarget.28279

Liza A. Wijler, Francina J. Dijk, Hanil Quirindongo, Danielle A.E. Raats, Bram Dorresteijn, Matthew J.W. Furber, Anne M. May, Onno Kranenburg,  and Miriam van Dijk
1094-1108
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint

Research Papers

Effectiveness of radiotherapy for local control in T3N0 rectal cancer managed with total mesorectal excision: a meta-analysis

Effectiveness of radiotherapy for local control in T3N0 rectal cancer managed with total mesorectal excision: a meta-analysis

https://doi.org/10.18632/oncotarget.28280

Michael Jonathan Kucharczyk, Andrew Bang, Michael C. Tjong, Stefania Papatheodorou,  and Jesus C. Fabregas
1109-1119
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint

Corrections

Correction: Oncogenic RAS-induced senescence in human primary thyrocytes: molecular effectors and inflammatory secretome involved

Correction: Oncogenic RAS-induced senescence in human primary thyrocytes: molecular effectors and inflammatory secretome involved

https://doi.org/10.18632/oncotarget.28027

Maria Grazia Vizioli, Joana Santos, Silvana Pilotti, Mara Mazzoni, Maria Chiara Anania, Claudia Miranda, Sonia Pagliardini, Marco A. Pierotti, Jesus Gil,  and Angela Greco
1120-1121
Correction  |  PDF  |  How to cite

Research Papers

HDAC inhibitors suppress protein poly(ADP-ribosyl)ation and DNA repair protein levels and phosphorylation status in hematologic cancer cells: implications for their use in combination with PARP inhibitors and chemotherapeutic drugs

HDAC inhibitors suppress protein poly(ADP-ribosyl)ation and DNA repair protein levels and phosphorylation status in hematologic cancer cells: implications for their use in combination with PARP inhibitors and chemotherapeutic drugs

https://doi.org/10.18632/oncotarget.28278

Benigno C. Valdez, Yago Nieto, Bin Yuan, David Murray,  and Borje S. Andersson
1122-1135
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Research Perspectives

FSP1, a novel KEAP1/NRF2 target gene regulating ferroptosis and radioresistance in lung cancers

FSP1, a novel KEAP1/NRF2 target gene regulating ferroptosis and radioresistance in lung cancers

https://doi.org/10.18632/oncotarget.28301

Nsengiyumva Emmanuel, Hongen Li, Jing Chen,  and Yilei Zhang
1136-1139
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Research Papers

Platelet-derived growth factor (PDGF) cross-signaling via non-corresponding receptors indicates bypassed signaling in colorectal cancer

Platelet-derived growth factor (PDGF) cross-signaling via non-corresponding receptors indicates bypassed signaling in colorectal cancer

https://doi.org/10.18632/oncotarget.28281

Romana Moench, Martin Gasser, Karol Nawalaniec, Tanja Grimmig, Amrendra K. Ajay, Larissa Camila Ribeiro de Souza, Minghua Cao, Yueming Luo, Petra Hoegger, Carmen M. Ribas, Jurandir M. Ribas-Filho, Osvaldo Malafaia, Reinhard Lissner, Li-Li Hsiao,  and Ana Maria Waaga-Gasser
1140-1152
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release  |  Order a Reprint

Corrections

Correction: Hyperthermia and associated changes in membrane fluidity potentiate P2X7 activation to promote tumor cell death

Correction: Hyperthermia and associated changes in membrane fluidity potentiate P2X7 activation to promote tumor cell death

https://doi.org/10.18632/oncotarget.27641

Paola de Andrade Mello, Shu Bian, Luiz Eduardo Baggio Savio, Haohai Zhang, Jingping Zhang, Wolfgang Junger, Márcia Rosângela Wink, Guido Lenz, Andréia Buffon, Yan Wu,  and Simon Christopher Robson
1153-1154
Correction  |  PDF  |  How to cite

Research Papers

Therapeutic efficacy of the humanized JAA-F11 anti-Thomsen-Friedenreich antibody constructs H2aL2a and H3L3 in human breast and lung cancer xenograft models

Therapeutic efficacy of the humanized JAA-F11 anti-Thomsen-Friedenreich antibody constructs H2aL2a and H3L3 in human breast and lung cancer xenograft models

https://doi.org/10.18632/oncotarget.28282

Diala Ghazal, Fatma Zalzala, John C. Fisk, Swetha Tati, Loukia G. Karacosta, Susan Morey, James R. Olson, Sally Quataert, Grace K. Dy,  and Kate Rittenhouse-Olson
1155-1164
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint

Addendum

Addendum: Resolution of radiation necrosis with bevacizumab following radiation therapy for primary CNS lymphoma

Addendum: Resolution of radiation necrosis with bevacizumab following radiation therapy for primary CNS lymphoma

https://doi.org/10.18632/oncotarget.28292

Eugene J. Vaios, Kristen A. Batich, Anne F. Buckley, Anastasie Dunn-Pirio, Mallika P. Patel, John P. Kirkpatrick, Ranjit Goudar,  and Katherine B. Peters
1165-1165
Addendum  |  PDF  |  How to cite

Research Papers

Nectin-4 is widely expressed in head and neck squamous cell carcinoma

Nectin-4 is widely expressed in head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.28299

Christine Sanders, Jan-Frederic Lau, Dimo Dietrich, Sebastian Strieth, Peter Brossart,  and Glen Kristiansen
1166-1173
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release  |  Order a Reprint

Addendum

Addendum: The value of comprehensive genomic sequencing to maximize the identification of clinically actionable alterations in advanced cancer patients: a case series

Addendum: The value of comprehensive genomic sequencing to maximize the identification of clinically actionable alterations in advanced cancer patients: a case series

https://doi.org/10.18632/oncotarget.28294

Kevin Drenner, Gargi D. Basu, Laurie J. Goodman, Audrey A. Ozols, Janine R. LoBello, Thomas Royce, Michael S. Gordon, Erkut H. Borazanci, Margaux A. Steinbach, Jeffrey Trent,  and Sunil Sharma
1174-1174
Addendum  |  PDF  |  How to cite

Research Papers

The serine protease matriptase inhibits migration and proliferation in multiple myeloma cells

The serine protease matriptase inhibits migration and proliferation in multiple myeloma cells

https://doi.org/10.18632/oncotarget.28300

Ida Steiro, Esten N. Vandsemb, Samah Elsaadi, Kristine Misund, Anne-Marit Sponaas, Magne Børset, Pegah Abdollahi,  and Tobias S. Slørdahl
1175-1186
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint

Corrections

Correction: THBS2 as a prognostic biomarker for patients diagnosed with metastatic pancreatic ductal adenocarcinoma

Correction: THBS2 as a prognostic biomarker for patients diagnosed with metastatic pancreatic ductal adenocarcinoma

https://doi.org/10.18632/oncotarget.28127

Phyllis A. Gimotty, Jacob E. Till, Shirsa Udgata, Naomi Takenaka, Stephanie S. Yee, Michael J. LaRiviere, Mark H. O’Hara, Kim A. Reiss, Peter O’Dwyer, Bryson W. Katona, Daniel Herman, Erica L. Carpenter,  and Kenneth S. Zaret
1187-1187
Correction  |  PDF  |  How to cite

Research Papers

Predictive molecular biomarkers for determining neoadjuvant chemosensitivity in muscle invasive bladder cancer

Predictive molecular biomarkers for determining neoadjuvant chemosensitivity in muscle invasive bladder cancer

https://doi.org/10.18632/oncotarget.28302

Neal Murphy, Andrew J. Shih, Paras Shah, Oksana Yaskiv, Houman Khalili, Anthony Liew, Annette T. Lee,  and Xin-Hua Zhu
1188-1200
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint

Retraction

Retraction: SAMMSON drives the self-renewal of liver tumor initiating cells through EZH2-dependent Wnt/β-catenin activation

Retraction: SAMMSON drives the self-renewal of liver tumor initiating cells through EZH2-dependent Wnt/β-catenin activation

https://doi.org/10.18632/oncotarget.28307

Xiaopeng Li, Ming Li, JiaLi Chen, Hua Dai, Liang Wang, Ying Xiong, Yuanbin Zhong,  and Lunli Zhang
1201-1201
Retraction  |  PDF  |  How to cite

Research Papers

Tumor hyaluronan as a novel biomarker in non-small cell lung cancer: A retrospective study

Tumor hyaluronan as a novel biomarker in non-small cell lung cancer: A retrospective study

https://doi.org/10.18632/oncotarget.28304

Jun Gong, Michelle Guan, Haesoo Kim, Natalie Moshayedi, Sejal Mehta, Galen Cook-Wiens, Brent K. Larson, Jenny Zhou, Rishi Patel, Isaac Lapite, Veronica R. Placencio-Hickok, Richard Tuli, Ronald B. Natale,  and Andrew E. Hendifar
1202-1214
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release  |  Order a Reprint

Addendum

Addendum: Liquid biopsy and multi-analyte testing guided treatment of HER2 positive periampullary adenocarcinoma with durable complete response after trastuzumab based therapy

Addendum: Liquid biopsy and multi-analyte testing guided treatment of HER2 positive periampullary adenocarcinoma with durable complete response after trastuzumab based therapy

https://doi.org/10.18632/oncotarget.28296

Rajnish Nagarkar, Darshana Patil, Sewanti Limaye, Pradip Devhare, Ashwini Ghaisas, Navin Srivastava, Sachin Apurwa, Sanket Patil, Jinumary John, Zarrine Raazi, Aditya Shreenivas, Janani Sambath, Ajay Srinivasan, Prashant Kumar, Dadasaheb Akolkar,  and Rajan Datar
1215-1215
Addendum  |  PDF  |  How to cite

Addendum

Addendum: Polyclonal on- and off-target resistance mutations in an EML4-ALK positive non-small cell lung cancer patient under ALK inhibition

Addendum: Polyclonal on- and off-target resistance mutations in an EML4-ALK positive non-small cell lung cancer patient under ALK inhibition

https://doi.org/10.18632/oncotarget.28293

Marcel Kemper, Georg Evers, Arik Bernard Schulze, Jan Sperveslage, Christoph Schülke, Georg Lenz, Thomas Herold, Wolfgang Hartmann, Hans-Ulrich Schildhaus,  and Annalen Bleckmann
1216-1216
Addendum  |  PDF  |  How to cite

Research Papers

MK256 is a novel CDK8 inhibitor with potent antitumor activity in AML through downregulation of the STAT pathway

MK256 is a novel CDK8 inhibitor with potent antitumor activity in AML through downregulation of the STAT pathway

https://doi.org/10.18632/oncotarget.28305

Jen-Chieh Lee, Shu Liu, Yucheng Wang, You Liang,  and David M. Jablons
1217-1236
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release  |  Order a Reprint

Research Papers

Mutation analysis performed on tumor biopsies from patients with newly-diagnosed germinal center aggressive B cell lymphomas

Mutation analysis performed on tumor biopsies from patients with newly-diagnosed germinal center aggressive B cell lymphomas

https://doi.org/10.18632/oncotarget.28309

Daniel J. Landsburg, Jennifer J.D. Morrissette, Stephen J. Schuster, Sunita D. Nasta, James N. Gerson, Stefan K. Barta, Jakub Svoboda, Elise A. Chong,  and Megan S. Lim
1237-1244
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release  |  Order a Reprint

Addendum

Addendum: Hyperprogression to a dual immune blockade followed by subsequent response with cabozantinib in metastatic poor-risk clear cell renal cell carcinoma with NOTCH mutation

Addendum: Hyperprogression to a dual immune blockade followed by subsequent response with cabozantinib in metastatic poor-risk clear cell renal cell carcinoma with NOTCH mutation

https://doi.org/10.18632/oncotarget.28312

Javier Molina-Cerrillo, Teresa Alonso-Gordoa, Alfredo Carrato,  and Enrique Grande
1245-1245
Addendum  |  PDF  |  How to cite

Research Perspectives

Treasures from trash in cancer research

Treasures from trash in cancer research

https://doi.org/10.18632/oncotarget.28308

Fabiano Cordeiro Moreira, Dionison Pereira Sarquis, Jorge Estefano Santana de Souza, Daniel de Souza Avelar, Taíssa Maria Thomaz Araújo, André Salim Khayat, Sidney Emanuel Batista dos Santos,  and Paulo Pimentel de Assumpção
1246-1257
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint

Retraction

Retraction: Long non-coding RNA XIST promotes cell growth and metastasis through regulating miR-139-5p mediated Wnt/β-catenin signaling pathway in bladder cancer

Retraction: Long non-coding RNA XIST promotes cell growth and metastasis through regulating miR-139-5p mediated Wnt/β-catenin signaling pathway in bladder cancer

https://doi.org/10.18632/oncotarget.28314

Yangyang Hu, Chao Deng, He Zhang, Jing Zhang, Bo Peng,  and Chuanyi Hu
1258-1258
Retraction  |  PDF  |  How to cite

Research Papers

Association of fall rate and functional status by APOE genotype in cancer survivors after exercise intervention

Association of fall rate and functional status by APOE genotype in cancer survivors after exercise intervention

https://doi.org/10.18632/oncotarget.28310

Gwendolyn J. McGinnis, Sarah Holden, Betty Yu, Charlton Ransom, Carolyn Guidarelli, Brian De, Kevin Diao, David Boyce, Charles R. Thomas Jr., Kerri Winters-Stone,  and Jacob Raber
1259-1270
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint

Addendum

Addendum: Multiple primary lung cancer displaying different EGFR and PTEN molecular profiles

Addendum: Multiple primary lung cancer displaying different EGFR and PTEN molecular profiles

https://doi.org/10.18632/oncotarget.28313

Zhouyu Zhu, Tao Yu,  and Ying Chai
1271-1271
Addendum  |  PDF  |  How to cite

Corrections

Correction: Evaluation of 6-mercaptopurine in a cell culture model of adaptable triple-negative breast cancer with metastatic potential

Correction: Evaluation of 6-mercaptopurine in a cell culture model of adaptable triple-negative breast cancer with metastatic potential

https://doi.org/10.18632/oncotarget.28311

Balraj Singh, Vanessa N. Sarli, Hannah E. Kinne, Anna Shamsnia,  and Anthony Lucci
1272-1272
Correction  |  PDF  |  How to cite

Reviews

Myeloid-derived suppressor cells: Cancer, autoimmune diseases, and more

Myeloid-derived suppressor cells: Cancer, autoimmune diseases, and more

https://doi.org/10.18632/oncotarget.28303

Masahiko Shibata, Kotaro Nanno, Daigo Yoshimori, Takahiro Nakajima, Makoto Takada, Takashi Yazawa, Kousaku Mimura, Norio Inoue, Takafumi Watanabe, Kazunoshin Tachibana, Satoshi Muto, Tomoyuki Momma, Yoshiyuki Suzuki, Koji Kono, Shungo Endo,  and Seiichi Takenoshita
1273-1285
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release  |  Order a Reprint

Research Papers

Essential amino acids as diagnostic biomarkers of hepatocellular carcinoma based on metabolic analysis

Essential amino acids as diagnostic biomarkers of hepatocellular carcinoma based on metabolic analysis

https://doi.org/10.18632/oncotarget.28306

Yuji Morine, Tohru Utsunomiya, Hisami Yamanaka-Okumura, Yu Saito, Shinichiro Yamada, Tetsuya Ikemoto, Satoru Imura, Shohei Kinoshita, Akiyoshi Hirayama, Yasuhito Tanaka,  and Mitsuo Shimada
1286-1298
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint


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