Editorial

Targeting MITF in the tolerancephase	Targeting MITF in the tolerancephase
https://doi.org/10.18632/oncotarget.9423 Imanol Arozarena, Michael P. Smith, and Claudia Wellbrock
54094-54095

Abstract  |  PDF  |  How to cite

Research Perspectives

Metformin and cancer: Quo vadis et cui bono	Metformin and cancer: Quo vadis et cui bono
https://doi.org/10.18632/oncotarget.10262 Javier A. Menendez, Begoña Martin-Castillo, and Jorge Joven
54096-54101

Abstract  |  PDF  |  Full Text  |  How to cite

Priority Research Papers

Novel function of MDA9/Syntenin SDCBP as a regulator of survival and stemness in glioma stem cells	Novel function of MDA9/Syntenin SDCBP as a regulator of survival and stemness in glioma stem cells
https://doi.org/10.18632/oncotarget.10851 Sarmistha Talukdar, Swadesh K. Das, Anjan K. Pradhan, Luni Emdad, Xue-Ning Shen, Jolene J. Windle, Devanand Sarkar, and Paul B. Fisher
54102-54119

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Effective combination therapies in preclinical endocrine resistant breast cancer models harboring ER mutations	Effective combination therapies in preclinical endocrine resistant breast cancer models harboring ER mutations
https://doi.org/10.18632/oncotarget.10852 Brendon Ladd, Anne Marie Mazzola, Teeru Bihani, Zhongwu Lai, James Bradford, Michael Collins, Evan Barry, Anne U. Goeppert, Hazel M. Weir, Kelly Hearne, Jonathan G. Renshaw, Morvarid Mohseni, Elaine Hurt, Sanjoo Jalla, Haifeng Bao, Robert Hollingsworth, Corinne Reimer, Michael Zinda, Stephen Fawell, and Celina M. D’Cruz
54120-54136

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

EGFRtargeted therapy results in dramatic early lung tumor regression accompanied by imaging response and immune infiltration in EGFR mutant transgenic mouse models	EGFRtargeted therapy results in dramatic early lung tumor regression accompanied by imaging response and immune infiltration in EGFR mutant transgenic mouse models
https://doi.org/10.18632/oncotarget.11021 Abhilash Venugopalan, Min-Jung Lee, Gang Niu, José Medina-Echeverz, Yusuke Tomita, Martin J. Lizak, Constance M. Cultraro, Robert Mark Simpson, Xiaoyuan Chen, Jane B. Trepel, and Udayan Guha
54137-54156

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ΔNp63 drives metastasis in breast cancer cells via PI3K/CD44v6 axis	ΔNp63 drives metastasis in breast cancer cells via PI3K/CD44v6 axis
https://doi.org/10.18632/oncotarget.11022 Simone Di Franco, Alice Turdo, Antonina Benfante, Maria L. Colorito, Miriam Gaggianesi, Tiziana Apuzzo, Raju Kandimalla, Aurora Chinnici, Daniela Barcaroli, Laura Rosa Mangiapane, Giuseppe Pistone, Salvatore Vieni, Eliana Gulotta, Francesco Dieli, Jan Paul Medema, Giorgio Stassi, Vincenzo De Laurenzi, and Matilde Todaro
54157-54173

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Upregulation of long noncoding RNA MIAT in aggressive form of chronic lymphocytic leukemias	Upregulation of long noncoding RNA MIAT in aggressive form of chronic lymphocytic leukemias
https://doi.org/10.18632/oncotarget.11099 Arash Sattari, Hasan Siddiqui, Farzaneh Moshiri, Apollinaire Ngankeu, Tatsuya Nakamura, Thomas J. Kipps, and Carlo M. Croce
54174-54182

Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers: Gerotarget (Focus on Aging)

Royal jelly promotes DAF16mediated proteostasis to tolerate βamyloid toxicity in C elegans model of Alzheimer’s disease	Royal jelly promotes DAF16mediated proteostasis to tolerate βamyloid toxicity in C elegans model of Alzheimer’s disease
https://doi.org/10.18632/oncotarget.10857 Xiaoxia Wang, Min Cao, and Yuqing Dong
54183-54193

Abstract  |  PDF  |  Full Text  |  How to cite

Age is associated with time in therapeutic range for warfarin therapy in patients with atrial fibrillation	Age is associated with time in therapeutic range for warfarin therapy in patients with atrial fibrillation
https://doi.org/10.18632/oncotarget.10944 Leiliane Rodrigues Marcatto, Luciana Sacilotto, Francisco Carlos da Costa Darrieux, Denise Tessariol Hachul, Maurício Ibrahim Scanavacca, Jose Eduardo Krieger, Alexandre Costa Pereira, and Paulo Caleb Junior Lima Santos
54194-54199

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Dosedependent genotype effects of BDNF Val66Met polymorphism on default mode network in early stage Alzheimer’s disease	Dosedependent genotype effects of BDNF Val66Met polymorphism on default mode network in early stage Alzheimer’s disease
https://doi.org/10.18632/oncotarget.11027 Pin-Hsuan Lin, Shih-Jen Tsai, Chi-Wei Huang, Liu Mu-En, Shih-Wei Hsu, Chen-Chang Lee, Nai-Ching Chen, Ya-Ting Chang, Min-Yu Lan, and Chiung-Chih Chang
54200-54214

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Increased Rab35 expression is a potential biomarker and implicated in the pathogenesis of Parkinson’s disease	Increased Rab35 expression is a potential biomarker and implicated in the pathogenesis of Parkinson’s disease
https://doi.org/10.18632/oncotarget.11090 Ching-Chi Chiu, Tu-Hsueh Yeh, Szu-Chia Lai, Yi-Hsin Weng, Yin-Cheng Huang, Yi-Chuan Cheng, Rou-Shayn Chen, Ying-Zu Huang, June Hung, Chiung-Chu Chen, Wey-Yil Lin, Hsiu-Chen Chang, Yu-Jie Chen, Chao-Lang Chen, Hsin-Yi Chen, Yan-Wei Lin, Yah-Huei Wu-Chou, Hung-Li Wang, and Chin-Song Lu
54215-54227

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Pathology

FOXC2 diseasemutations identified in lymphedemadistichiasis patients cause both loss and gain of protein function	FOXC2 diseasemutations identified in lymphedemadistichiasis patients cause both loss and gain of protein function
https://doi.org/10.18632/oncotarget.9797 Daniela Tavian, Sara Missaglia, Paolo E. Maltese, Sandro Michelini, Alessandro Fiorentino, Maurizio Ricci, Roberta Serrani, Michael A. Walter, and Matteo Bertelli
54228-54239

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Interferon gamma peptidomimetic targeted to interstitial myofibroblasts attenuates renal fibrosis after unilateral ureteral obstruction in mice	Interferon gamma peptidomimetic targeted to interstitial myofibroblasts attenuates renal fibrosis after unilateral ureteral obstruction in mice
https://doi.org/10.18632/oncotarget.11095 Fariba Poosti, Ruchi Bansal, Saleh Yazdani, Jai Prakash, Leonie Beljaars, Jacob van den Born, Martin H. de Borst, Harry van Goor, Jan-Luuk Hillebrands, and Klaas Poelstra
54240-54252

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tumor specific mutations in TERT promoter and CTNNB1 gene in hepatitis B and hepatitis C related hepatocellular carcinoma	Tumor specific mutations in TERT promoter and CTNNB1 gene in hepatitis B and hepatitis C related hepatocellular carcinoma
https://doi.org/10.18632/oncotarget.9801 Francesca Pezzuto, Francesco Izzo, Luigi Buonaguro, Clorinda Annunziata, Fabiana Tatangelo, Gerardo Botti, Franco M. Buonaguro, and Maria Lina Tornesello
54253-54262

Abstract  |  PDF  |  Full Text  |  How to cite

Inhibition of heat shock protein 90 improves pulmonary arteriole remodeling in pulmonary arterial hypertension	Inhibition of heat shock protein 90 improves pulmonary arteriole remodeling in pulmonary arterial hypertension
https://doi.org/10.18632/oncotarget.10855 Guo-Kun Wang, Song-Hua Li, Zhi-Min Zhao, Su-Xuan Liu, Guan-Xin Zhang, Fan Yang, Yang Wang, Feng Wu, Xian-Xian Zhao, and Zhi-Yun Xu
54263-54273

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Cardiac fibrosis in mouse expressing DsRed tetramers involves chronic autophagy and proteasome degradation insufficiency	Cardiac fibrosis in mouse expressing DsRed tetramers involves chronic autophagy and proteasome degradation insufficiency
https://doi.org/10.18632/oncotarget.11026 Tsung-Hsien Chen, Mei-Ru Chen, Tzu-Yin Chen, Tzu-Chin Wu, Shan-Wen Liu, Ching-Han Hsu, Gan-Guang Liou, Yu-Ying Kao, Guo-Chung Dong, Pao-Hsien Chu, Jiunn-Wang Liao, and Kurt Ming-Chao Lin
54274-54289

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

NLRP3 inflammasome activation is involved in Ang IIinduced kidney damage via mitochondrial dysfunction	NLRP3 inflammasome activation is involved in Ang IIinduced kidney damage via mitochondrial dysfunction
https://doi.org/10.18632/oncotarget.11091 Yi Wen, Yiran Liu, Taotao Tang, Linli Lv, Hong Liu, Kunling Ma, and Bicheng Liu
54290-54302

Abstract  |  PDF  |  Full Text  |  How to cite

Binge ethanol exposure causes endoplasmic reticulum stress oxidative stress and tissue injury in the pancreas	Binge ethanol exposure causes endoplasmic reticulum stress oxidative stress and tissue injury in the pancreas
https://doi.org/10.18632/oncotarget.11103 Zhenhua Ren, Xin Wang, Mei Xu, Fanmuyi Yang, Jacqueline A. Frank, Zun-ji Ke, and Jia Luo
54303-54316

Abstract  |  PDF  |  Full Text  |  How to cite

Prolyl hydroxylase 2 PHD2 inhibition protects human renal epithelial cells and mice kidney from hypoxia injury	Prolyl hydroxylase 2 PHD2 inhibition protects human renal epithelial cells and mice kidney from hypoxia injury
https://doi.org/10.18632/oncotarget.11104 Yi Fang, Hui Zhang, Yihong Zhong, and Xiaoqiang Ding
54317-54328

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Towards a multi protein and mRNA expression of biological predictive and distinguish model for post stroke depression	Towards a multi protein and mRNA expression of biological predictive and distinguish model for post stroke depression
https://doi.org/10.18632/oncotarget.11105 Yingying Yue, Haitang Jiang, Rui Liu, Yingying Yin, Yuqun Zhang, Jinfeng Liang, Shenghua Li, Jun Wang, Jianxin Lu, Deqin Geng, Aiqin Wu, and Yonggui Yuan
54329-54338

Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers: Immunology

Inherent low Erk and p38 activity reduce Fas Ligand expression and degranulation in T helper 17 cells leading to activation induced cell death resistance	Inherent low Erk and p38 activity reduce Fas Ligand expression and degranulation in T helper 17 cells leading to activation induced cell death resistance
https://doi.org/10.18632/oncotarget.10913 Doureradjou Peroumal, Thiruvaimozhi Abimannan, Ravichandra Tagirasa, Jyothi Ranjan Parida, Santosh Kumar Singh, Prasantha Padhan, and Satish Devadas
54339-54359

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Combination of specific allergen and probiotics induces specific regulatory B cells and enhances specific immunotherapy effect on allergic rhinitis	Combination of specific allergen and probiotics induces specific regulatory B cells and enhances specific immunotherapy effect on allergic rhinitis
https://doi.org/10.18632/oncotarget.10946 Ling-Zhi Xu, Li-Tao Yang, Shu-Qi Qiu, Gui Yang, Xiang-Qian Luo, Bei-Ping Miao, Xiao-Rui Geng, Zhi-Qiang Liu, Jun Liu, Zhong Wen, Shuai Wang, Huan-Ping Zhang, Jing Li, Zhi-Gang Liu, Hua-Bin Li, and Ping-Chang Yang
54360-54369

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ADAR1 is vital for B cell lineage development in the mouse bone marrow	ADAR1 is vital for B cell lineage development in the mouse bone marrow
https://doi.org/10.18632/oncotarget.11029 Victoria Marcu-Malina, Sanja Goldberg, Einav Vax, Ninette Amariglio, Itamar Goldstein, and Gideon Rechavi
54370-54379

Abstract  |  PDF  |  Full Text  |  How to cite

Systematic identification of immunodominant CD4+ T cell responses to HpaA in Helicobacter pylori infected individuals	Systematic identification of immunodominant CD4+ T cell responses to HpaA in Helicobacter pylori infected individuals
https://doi.org/10.18632/oncotarget.11092 Jian Hu, Li Chen, Wuchen Yang, Bin Li, Heqiang Sun, Shanshan Wei, Yafei He, Zhuo Zhao, Shiming Yang, Quanming Zou, Weisan Chen, Hong Guo, and Chao Wu
54380-54391

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Myeloid cell expressed proprotein convertase FURIN attenuates inflammation	Myeloid cell expressed proprotein convertase FURIN attenuates inflammation
https://doi.org/10.18632/oncotarget.11106 Zuzet Martinez Cordova, Anna Grönholm, Ville Kytölä, Valentina Taverniti, Sanna Hämäläinen, Saara Aittomäki, Wilhelmiina Niininen, Ilkka Junttila, Antti Ylipää, Matti Nykter, and Marko Pesu
54392-54404

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers

White matter degeneration in subjective cognitive decline: a diffusion tensor imaging study	White matter degeneration in subjective cognitive decline: a diffusion tensor imaging study
https://doi.org/10.18632/oncotarget.10091 Xuan-yu Li, Zhen-chao Tang, Yu Sun, Jie Tian, Zhen-yu Liu, and Ying Han
54405-54414

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Downregulation of the neonatal Fc receptor expression in nonsmall cell lung cancer tissue is associated with a poor prognosis	Downregulation of the neonatal Fc receptor expression in nonsmall cell lung cancer tissue is associated with a poor prognosis
https://doi.org/10.18632/oncotarget.10074 Emilie Dalloneau, Nadine Baroukh, Konstantinos Mavridis, Agnès Maillet, Fabien Gueugnon, Yves Courty, Agnès Petit, Thomas Kryza, Maguy Del Rio, Serge Guyetant, Diana Carolina Cadena Castaneda, Christine Dhommée, Christophe Arnoult, Andreas Scorilas, Valérie Gouilleux-Gruart, and Nathalie Heuzé-Vourc’h
54415-54429

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Scaffold attachment factor A SAFA and Ku temporally regulate repair of radiationinduced clustered genome lesions	Scaffold attachment factor A SAFA and Ku temporally regulate repair of radiationinduced clustered genome lesions
https://doi.org/10.18632/oncotarget.9914 Muralidhar L. Hegde, Arijit Dutta, Chunying Yang, Anil K. Mantha, Pavana M. Hegde, Arvind Pandey, Shiladitya Sengupta, Yaping Yu, Patrick Calsou, David Chen, Susan P. Lees-Miller, and Sankar Mitra
54430-54444

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Importance of the type I insulinlike growth factor receptor in HER2 FGFR2 and METunamplified gastric cancer with and without Ras pathway activation	Importance of the type I insulinlike growth factor receptor in HER2 FGFR2 and METunamplified gastric cancer with and without Ras pathway activation
https://doi.org/10.18632/oncotarget.10642 Marina Saisana, S. Michael Griffin, and Felicity E.B. May
54445-54462

Abstract  |  PDF  |  Full Text  |  How to cite

Polypeptide Nacetylgalactosaminyltransferase6 expression independently predicts poor overall survival in patients with lung adenocarcinoma after curative resection	Polypeptide Nacetylgalactosaminyltransferase6 expression independently predicts poor overall survival in patients with lung adenocarcinoma after curative resection
https://doi.org/10.18632/oncotarget.9810 Zhi Li, Sohsuke Yamada, Ying Wu, Ke-Yong Wang, Yun-Peng Liu, Hidetaka Uramoto, Kimitoshi Kohno, and Yasuyuki Sasaguri
54463-54473

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The urokinase receptorderived cyclic peptide [SRSRY] suppresses neovascularization and intravasation of osteosarcoma and chondrosarcoma cells	The urokinase receptorderived cyclic peptide [SRSRY] suppresses neovascularization and intravasation of osteosarcoma and chondrosarcoma cells
https://doi.org/10.18632/oncotarget.9976 Vincenzo Ingangi, Katia Bifulco, Ali Munaim Yousif, Concetta Ragone, Maria Letizia Motti, Domenica Rea, Michele Minopoli, Giovanni Botti, Giuseppe Scognamiglio, Flavio Fazioli, Michele Gallo, Annarosaria De Chiara, Claudio Arra, Paolo Grieco, and Maria Vincenza Carriero
54474-54487

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prognostic significance of PLIN1 expression in human breast cancer	Prognostic significance of PLIN1 expression in human breast cancer
https://doi.org/10.18632/oncotarget.10239 Cefan Zhou, Ming Wang, Li Zhou, Yi Zhang, Weiyong Liu, Wenying Qin, Rong He, Yang Lu, Yefu Wang, Xing-Zhen Chen, and Jingfeng Tang
54488-54502

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miRNA193a5p repression of p73 controls Cisplatin chemoresistance in primary bone tumors	miRNA193a5p repression of p73 controls Cisplatin chemoresistance in primary bone tumors
https://doi.org/10.18632/oncotarget.10950 Camille Jacques, Lidia Rodriguez Calleja, Marc Baud’huin, Thibaut Quillard, Dominique Heymann, François Lamoureux, and Benjamin Ory
54503-54514

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Crizotinib inhibits NF2associated schwannoma through inhibition of focal adhesion kinase 1	Crizotinib inhibits NF2associated schwannoma through inhibition of focal adhesion kinase 1
https://doi.org/10.18632/oncotarget.10248 Scott Troutman, Susana Moleirinho, Smitha Kota, Kendall Nettles, Mohammad Fallahi, Gary L. Johnson, and Joseph L. Kissil
54515-54525

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Targeted next generation sequencing of endoscopic ultrasound acquired cytology from ampullary and pancreatic adenocarcinoma has the potential to aid patient stratification for optimal therapy selection	Targeted next generation sequencing of endoscopic ultrasound acquired cytology from ampullary and pancreatic adenocarcinoma has the potential to aid patient stratification for optimal therapy selection
https://doi.org/10.18632/oncotarget.9440 Ferga C. Gleeson, Sarah E. Kerr, Benjamin R. Kipp, Jesse S. Voss, Douglas M. Minot, Zheng Jin Tu, Michael R. Henry, Rondell P. Graham, George Vasmatzis, John C. Cheville, Konstantinos N. Lazaridis, and Michael J. Levy
54526-54536

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Induction of apoptosis and autophagy via mitochondria and PI3K/Akt/mTORmediated pathways by E adenophorum in hepatocytes of saanen goat	Induction of apoptosis and autophagy via mitochondria and PI3K/Akt/mTORmediated pathways by E adenophorum in hepatocytes of saanen goat
https://doi.org/10.18632/oncotarget.10402 Yajun He, Quan Mo, Biao Luo, Yan Qiao, Ruiguang Xu, Zhicai Zuo, Xiang Nong, Junliang Deng, Guangneng Peng, Wei He, Yahui Wei, and Yanchun Hu
54537-54548

Abstract  |  PDF  |  Full Text  |  How to cite

Artificial small RNA for sequence specific cleavage of target RNA through RNase III endonuclease Dicer	Artificial small RNA for sequence specific cleavage of target RNA through RNase III endonuclease Dicer
https://doi.org/10.18632/oncotarget.9582 Wen Xu, Yuchen Liu, Yali Liu, Li Liu, Yonghao Zhan, Chengle Zhuang, Junhao Lin, Mingwei Chen, Jianfa Li, Zhiming Cai, Weiren Huang, and Yong Zhang
54549-54554

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Independent evaluation of a FOXM1based quantitative malignancy diagnostic system qMIDS on head and neck squamous cell carcinomas	Independent evaluation of a FOXM1based quantitative malignancy diagnostic system qMIDS on head and neck squamous cell carcinomas
https://doi.org/10.18632/oncotarget.10512 Hong Ma, Haiyan Dai, Xiaofeng Duan, Zhenglong Tang, Rui Liu, Kunjun Sun, Ke Zhou, Hao Chen, Hang Xiang, Jinsheng Wang, Qiong Gao, Yuan Zou, Hong Wan, and Muy-Teck Teh
54555-54563

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Systemic immuneinflammation index predicts the clinical outcome in patients with metastatic renal cell cancer treated with sunitinib	Systemic immuneinflammation index predicts the clinical outcome in patients with metastatic renal cell cancer treated with sunitinib
https://doi.org/10.18632/oncotarget.10515 Cristian Lolli, Umberto Basso, Lisa Derosa, Emanuela Scarpi, Teodoro Sava, Matteo Santoni, Simon J. Crabb, Francesco Massari, Michele Aieta, Vincenza Conteduca, Marco Maruzzo, Francesca La Russa, Matthew Wheater, Rossana Berardi, Luca Galli, and Ugo De Giorgi
54564-54571

Abstract  |  PDF  |  Full Text  |  How to cite

Posttranscriptional knowledge in pathway analysis increases the accuracy of phenotypes classification	Posttranscriptional knowledge in pathway analysis increases the accuracy of phenotypes classification
https://doi.org/10.18632/oncotarget.9788 Salvatore Alaimo, Rosalba Giugno, Mario Acunzo, Dario Veneziano, Alfredo Ferro, and Alfredo Pulvirenti
54572-54582

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Preclinical evaluation of potential therapeutic targets in dedifferentiated liposarcoma	Preclinical evaluation of potential therapeutic targets in dedifferentiated liposarcoma
https://doi.org/10.18632/oncotarget.10518 Robert Hanes, Iwona Grad, Susanne Lorenz, Eva W. Stratford, Else Munthe, Chilamakuri Chandra Sekhar Reddy, Leonardo A. Meza-Zepeda, and Ola Myklebost
54583-54595

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The downregulated ING5 expression in lung cancer: A potential target of gene therapy	The downregulated ING5 expression in lung cancer: A potential target of gene therapy
https://doi.org/10.18632/oncotarget.10519 Shuang Zhao, Xue-feng Yang, Dao-fu Shen, Yang Gao, Shuai Shi, Ji-cheng Wu, Hong-xu Liu, Hong-zhi Sun, Rong-jian Su, and Hua-chuan Zheng
54596-54615

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification and validation of regulatory SNPs that modulate transcription factor chromatin binding and gene expression in prostate cancer	Identification and validation of regulatory SNPs that modulate transcription factor chromatin binding and gene expression in prostate cancer
https://doi.org/10.18632/oncotarget.10520 Hong-Jian Jin, Segun Jung, Auditi R. DebRoy, and Ramana V. Davuluri
54616-54626

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MET amplification in metastatic colorectal cancer: an acquired response to EGFR inhibition not a de novo phenomenon	MET amplification in metastatic colorectal cancer: an acquired response to EGFR inhibition not a de novo phenomenon
https://doi.org/10.18632/oncotarget.10559 Kanwal Raghav, Van Morris, Chad Tang, Pia Morelli, Hesham M. Amin, Ken Chen, Ganiraju C. Manyam, Bradley Broom, Michael J. Overman, Kenna Shaw, Funda Meric-Bernstam, Dipen Maru, David Menter, Lee M. Ellis, Cathy Eng, David Hong, and Scott Kopetz
54627-54631

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Annexin 2A sustains glioblastoma cell dissemination and proliferation	Annexin 2A sustains glioblastoma cell dissemination and proliferation
https://doi.org/10.18632/oncotarget.10565 Francesca Maule, Silvia Bresolin, Elena Rampazzo, Daniele Boso, Alessandro Della Puppa, Giovanni Esposito, Elena Porcù, Stefania Mitola, Giuseppe Lombardi, Benedetta Accordi, Manuela Tumino, Giuseppe Basso, and Luca Persano
54632-54649

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Specific patterns of PIWIinteracting small noncoding RNA expression in dysplastic liver nodules and hepatocellular carcinoma	Specific patterns of PIWIinteracting small noncoding RNA expression in dysplastic liver nodules and hepatocellular carcinoma
https://doi.org/10.18632/oncotarget.10567 Francesca Rizzo, Antonio Rinaldi, Giovanna Marchese, Elena Coviello, Assunta Sellitto, Angela Cordella, Giorgio Giurato, Giovanni Nassa, Maria Ravo, Roberta Tarallo, Luciano Milanesi, Anna Destro, Guido Torzilli, Massimo Roncalli, Luca Di Tommaso, and Alessandro Weisz
54650-54661

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Surgical resection and radiofrequency ablation initiate cancer in cytokeratin19+ liver cells deficient for p53 and Rb	Surgical resection and radiofrequency ablation initiate cancer in cytokeratin19+ liver cells deficient for p53 and Rb
https://doi.org/10.18632/oncotarget.9952 Ramadhan B. Matondo, Mathilda J.M. Toussaint, Klaas M. Govaert, Luciel D. van Vuuren, Sathidpak Nantasanti, Maarten W. Nijkamp, Shusil K. Pandit, Peter C.J. Tooten, Mirjam H. Koster, Kaylee Holleman, Arend Schot, Guoqiang Gu, Bart Spee, Tania Roskams, Inne Borel Rinkes, Baukje Schotanus, Onno Kranenburg, and Alain de Bruin
54662-54675

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Circulating exosomes potentiate tumor malignant properties in a mouse model of chronic sleep fragmentation	Circulating exosomes potentiate tumor malignant properties in a mouse model of chronic sleep fragmentation
https://doi.org/10.18632/oncotarget.10578 Abdelnaby Khalyfa, Isaac Almendros, Alex Gileles-Hillel, Mahzad Akbarpour, Wojciech Trzepizur, Babak Mokhlesi, Lei Huang, Jorge Andrade, Ramon Farré, and David Gozal
54676-54690

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Glutamine deprivation plus BPTES alters etoposide and cisplatininduced apoptosis in triple negative breast cancer cells	Glutamine deprivation plus BPTES alters etoposide and cisplatininduced apoptosis in triple negative breast cancer cells
https://doi.org/10.18632/oncotarget.10579 Lian Chen, Hengmin Cui, Jing Fang, Huidan Deng, Ping Kuang, Hongrui Guo, Xun Wang, and Ling Zhao
54691-54701

Abstract  |  PDF  |  Full Text  |  How to cite

Gallic acid inhibition of SrcStat3 signaling overcomes acquired resistance to EGF receptor tyrosine kinase inhibitors in advanced nonsmall cell lung cancer	Gallic acid inhibition of SrcStat3 signaling overcomes acquired resistance to EGF receptor tyrosine kinase inhibitors in advanced nonsmall cell lung cancer
https://doi.org/10.18632/oncotarget.10581 Ai N.H. Phan, Tuyen N.M. Hua, Min-Kyu Kim, Vu T.A. Vo, Jong-Whan Choi, Hyun-Won Kim, Jin Kyung Rho, Ki Woo Kim, and Yangsik Jeong
54702-54713

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

HDAC6 inhibition prevents TNFαinduced caspase 3 activation in lung endothelial cell and maintains cellcell junctions	HDAC6 inhibition prevents TNFαinduced caspase 3 activation in lung endothelial cell and maintains cellcell junctions
https://doi.org/10.18632/oncotarget.10591 Jinyan Yu, Mengshi Ma, Zhongsen Ma, and Jian Fu
54714-54722

Abstract  |  PDF  |  Full Text  |  How to cite

Inhibition of primary breast tumor growth and metastasis using a neuropilin1 transmembrane domain interfering peptide	Inhibition of primary breast tumor growth and metastasis using a neuropilin1 transmembrane domain interfering peptide
https://doi.org/10.18632/oncotarget.10101 Alexia Arpel, Coralie Gamper, Caroline Spenlé, Aurore Fernandez, Laurent Jacob, Nadège Baumlin, Patrice Laquerriere, Gertraud Orend, Gérard Crémel, and Dominique Bagnard
54723-54732

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MALAT1 promotes osteosarcoma development by targeting TGFA via MIR376A	MALAT1 promotes osteosarcoma development by targeting TGFA via MIR376A
https://doi.org/10.18632/oncotarget.10752 Wei Luo, Hongbo He, Wenfeng Xiao, Qing Liu, Zhenhan Deng, Yaojuan Lu, Qian Wang, Qiping Zheng, and Yusheng Li
54733-54743

Abstract  |  PDF  |  Full Text  |  How to cite

PAX3 is a novel tumor suppressor by regulating the activities of major signaling pathways and transcription factor FOXO3a in thyroid cancer	PAX3 is a novel tumor suppressor by regulating the activities of major signaling pathways and transcription factor FOXO3a in thyroid cancer
https://doi.org/10.18632/oncotarget.10753 Wei Liu, Fang Sui, Jiazhe Liu, Meichen Wang, Sijia Tian, Meiju Ji, Bingyin Shi, and Peng Hou
54744-54757

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Comprehensive assessment of the expression of the SWI/SNF complex defines two distinct prognostic subtypes of ovarian clear cell carcinoma	Comprehensive assessment of the expression of the SWI/SNF complex defines two distinct prognostic subtypes of ovarian clear cell carcinoma
https://doi.org/10.18632/oncotarget.10181 Hisham Abou-Taleb, Ken Yamaguchi, Noriomi Matsumura, Ryusuke Murakami, Hidekatsu Nakai, Koichiro Higasa, Yasuaki Amano, Kaoru Abiko, Yumiko Yoshioka, Junzo Hamanishi, Masafumi Koshiyama, Tsukasa Baba, Ryo Yamada, Fumihiko Matsuda, Ikuo Konishi, and Masaki Mandai
54758-54770

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Association between single nucleotide polymorphisms in the TSPYL6 gene and breast cancer susceptibility in the Han Chinese population	Association between single nucleotide polymorphisms in the TSPYL6 gene and breast cancer susceptibility in the Han Chinese population
https://doi.org/10.18632/oncotarget.10754 Ming Liu, Bin Li, Wen Guo, Xiyang Zhang, Zhengshuai Chen, Jingjie Li, Mengdan Yan, Chao Chen, and Tianbo Jin
54771-54781

Abstract  |  PDF  |  Full Text  |  How to cite

Cooperation between AlphavBeta3 integrin and the fibroblast growth factor receptor enhances proliferation of Hoxoverexpressing acute myeloid leukemia cells	Cooperation between AlphavBeta3 integrin and the fibroblast growth factor receptor enhances proliferation of Hoxoverexpressing acute myeloid leukemia cells
https://doi.org/10.18632/oncotarget.10189 Chirag A. Shah, Ling Bei, Hao Wang, Jessica K. Altman, Leonidas C. Platanias, and Elizabeth A. Eklund
54782-54794

Abstract  |  PDF  |  Full Text  |  How to cite

Hypoxiatargeted 131I therapy of hepatocellular cancer after systemic mesenchymal stem cellmediated sodium iodide symporter gene delivery	Hypoxiatargeted 131I therapy of hepatocellular cancer after systemic mesenchymal stem cellmediated sodium iodide symporter gene delivery
https://doi.org/10.18632/oncotarget.10758 Andrea M. Müller, Kathrin A. Schmohl, Kerstin Knoop, Christina Schug, Sarah Urnauer, Anna Hagenhoff, Dirk-André Clevert, Michael Ingrisch, Hanno Niess, Janette Carlsen, Christian Zach, Ernst Wagner, Peter Bartenstein, Peter J. Nelson, and Christine Spitzweg
54795-54810

Abstract  |  PDF  |  Full Text  |  How to cite

Regression of experimental NISexpressing breast cancer brain metastases in response to radioiodide/gemcitabine dual therapy	Regression of experimental NISexpressing breast cancer brain metastases in response to radioiodide/gemcitabine dual therapy
https://doi.org/10.18632/oncotarget.10238 Corinne Renier, John Do, Andrea Reyna-Neyra, Deshka Foster, Abhijit De, Hannes Vogel, Stefanie S. Jeffrey, Victor Tse, Nancy Carrasco, and Irene Wapnir
54811-54824

Abstract  |  PDF  |  Full Text  |  How to cite

Mutation profiling of 19 candidate genes in acute myeloid leukemia suggests significance of DNMT3A mutations	Mutation profiling of 19 candidate genes in acute myeloid leukemia suggests significance of DNMT3A mutations
https://doi.org/10.18632/oncotarget.10240 Sang-Yong Shin, Seung-Tae Lee, Hee-Jin Kim, Eun Hae Cho, Jong-Won Kim, Silvia Park, Chul Won Jung, and Sun-Hee Kim
54825-54837

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR34b3 and miR449a inhibit malignant progression of nasopharyngeal carcinoma by targeting lactate dehydrogenase A	MiR34b3 and miR449a inhibit malignant progression of nasopharyngeal carcinoma by targeting lactate dehydrogenase A
https://doi.org/10.18632/oncotarget.10761 Huiling Li, Xiaoling Li, Xiaolu Ge, Liqing Jia, Zhezhe Zhang, Renpeng Fang, Jing Yang, Jianpin Liu, Shuping Peng, Ming Zhou, Juanjuan Xiang, Zhaoyang Zeng, Wen Zhou, Wei Xiong, Gaoming Xiao, Li Fang, Gui-yuan Li, and Zheng Li
54838-54851

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Lung cancer exosomes as drivers of epithelial mesenchymal transition	Lung cancer exosomes as drivers of epithelial mesenchymal transition
https://doi.org/10.18632/oncotarget.10243 Mohammad A. Rahman, Jennifer F. Barger, Francesca Lovat, Min Gao, Gregory A. Otterson, and Patrick Nana-Sinkam
54852-54866

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genomic similarity between gastroesophageal junction and esophageal Barrett’s adenocarcinomas	Genomic similarity between gastroesophageal junction and esophageal Barrett’s adenocarcinomas
https://doi.org/10.18632/oncotarget.10253 Daysha Ferrer-Torres, Derek J. Nancarrow, Rork Kuick, Dafydd G. Thomas, Ernest Nadal, Jules Lin, Andrew C. Chang, Rishindra M. Reddy, Mark B. Orringer, Jeremy M. G. Taylor, Thomas D. Wang, and David G. Beer
54867-54882

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

FoxO proteins or loss of functional p53 maintain stemness of glioblastoma stem cells and survival after ionizing radiation plus PI3K/mTOR inhibition	FoxO proteins or loss of functional p53 maintain stemness of glioblastoma stem cells and survival after ionizing radiation plus PI3K/mTOR inhibition
https://doi.org/10.18632/oncotarget.10702 Elke Firat, and Gabriele Niedermann
54883-54896

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PIM kinases as therapeutic targets against advanced melanoma	PIM kinases as therapeutic targets against advanced melanoma
https://doi.org/10.18632/oncotarget.10703 Batool Shannan, Andrea Watters, Quan Chen, Stefan Mollin, Markus Dörr, Eric Meggers, Xiaowei Xu, Phyllis A. Gimotty, Michela Perego, Ling Li, Joseph Benci, Clemens Krepler, Patricia Brafford, Jie Zhang, Zhi Wei, Gao Zhang, Qin Liu, Xiangfan Yin, Katherine L. Nathanson, Meenhard Herlyn, and Adina Vultur
54897-54912

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MIEN1 drives breast tumor cell migration by regulating cytoskeletalfocal adhesion dynamics	MIEN1 drives breast tumor cell migration by regulating cytoskeletalfocal adhesion dynamics
https://doi.org/10.18632/oncotarget.10798 Marilyne Kpetemey, Pankaj Chaudhary, Timothy Van Treuren, and Jamboor K. Vishwanatha
54913-54924

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Photoimmunotheranostic agents for triplenegative breast cancer diagnosis and therapy that can be activated on demand	Photoimmunotheranostic agents for triplenegative breast cancer diagnosis and therapy that can be activated on demand
https://doi.org/10.18632/oncotarget.10705 Manal Amoury, Dirk Bauerschlag, Felix Zeppernick, Verena von Felbert, Nina Berges, Stefano Di Fiore, Isabell Mintert, Andreas Bleilevens, Nicolai Maass, Karen Bräutigam, Ivo Meinhold-Heerlein, Elmar Stickeler, Stefan Barth, Rainer Fischer, and Ahmad Fawzi Hussain
54925-54936

Abstract  |  PDF  |  Full Text  |  How to cite

MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4	MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4
https://doi.org/10.18632/oncotarget.10709 Chengyuan Xue, Denise M.T. Yu, Samuele Gherardi, Jessica Koach, Giorgio Milazzo, Laura Gamble, Bing Liu, Emanuele Valli, Amanda J. Russell, Wendy B. London, Tao Liu, Belamy B. Cheung, Glenn M. Marshall, Giovanni Perini, Michelle Haber, and Murray D. Norris
54937-54951

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tumor growth accelerated by chemotherapyinduced senescent cells is suppressed by treatment with IL12 producing cellular vaccines	Tumor growth accelerated by chemotherapyinduced senescent cells is suppressed by treatment with IL12 producing cellular vaccines
https://doi.org/10.18632/oncotarget.10712 Jana Simova, Olena Sapega, Terezie Imrichova, Ivan Stepanek, Lenka Kyjacova, Romana Mikyskova, Marie Indrova, Jana Bieblova, Jan Bubenik, Jiri Bartek, Zdenek Hodny, and Milan Reinis
54952-54964

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Plasma MiRNA alterations between NSCLC patients harboring Del19 and L858R EGFR mutations	Plasma MiRNA alterations between NSCLC patients harboring Del19 and L858R EGFR mutations
https://doi.org/10.18632/oncotarget.10829 Yihan Ma, Peiqi Xu, Yanjun Mi, Wenyi Wang, Xiaoyan Pan, Xiaoting Wu, Qi He, Hongming Liu, Weiwei Tang, and Hanxiang An
54965-54972

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Expression of CDX2 in gastric cardia adenocarcinoma and its correlation with H pylori and cell proliferation	Expression of CDX2 in gastric cardia adenocarcinoma and its correlation with H pylori and cell proliferation
https://doi.org/10.18632/oncotarget.10362 Ying Zhang, Hu Wang, Chao Bi, Yinping Xiao, and Zhaoyong Liu
54973-54982

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

NHERF1 a novel GPER associated protein increases stability and activation of GPER in ERpositive breast cancer	NHERF1 a novel GPER associated protein increases stability and activation of GPER in ERpositive breast cancer
https://doi.org/10.18632/oncotarget.10713 Ran Meng, Qiong Qin, Ying Xiong, Yan Wang, Junfang Zheng, Yuan Zhao, Tao Tao, Qiqi Wang, Hua Liu, Songlin Wang, Wen G. Jiang, and Junqi He
54983-54997

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR328 targeting PIM1 inhibits proliferation and migration of pulmonary arterial smooth muscle cells in PDGFBB signaling pathway	MiR328 targeting PIM1 inhibits proliferation and migration of pulmonary arterial smooth muscle cells in PDGFBB signaling pathway
https://doi.org/10.18632/oncotarget.10714 Zhengjiang Qian, Limin Zhang, Jidong Chen, Yanjiao Li, Kang Kang, Junle Qu, Zhiwei Wang, Yujia Zhai, Li Li, and Deming Gou
54998-55011

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiRSEA: Discovering the pathways regulated by dysfunctional MicroRNAs	MiRSEA: Discovering the pathways regulated by dysfunctional MicroRNAs
https://doi.org/10.18632/oncotarget.10839 Junwei Han, Siyao Liu, Yunpeng Zhang, Yanjun Xu, Ying Jiang, Chunlong Zhang, Chunquan Li, and Xia Li
55012-55025

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

CNS germinomas are characterized by global demethylation chromosomal instability and mutational activation of the Kit Ras/Raf/Erk and Aktpathways	CNS germinomas are characterized by global demethylation chromosomal instability and mutational activation of the Kit Ras/Raf/Erk and Aktpathways
https://doi.org/10.18632/oncotarget.10392 Simone Laura Schulte, Andreas Waha, Barbara Steiger, Dorota Denkhaus, Evelyn Dörner, Gabriele Calaminus, Ivo Leuschner, and Torsten Pietsch
55026-55042

Abstract  |  PDF  |  Full Text  |  How to cite

Adrenomedullin promotes the growth of pancreatic ductal adenocarcinoma through recruitment of myelomonocytic cells	Adrenomedullin promotes the growth of pancreatic ductal adenocarcinoma through recruitment of myelomonocytic cells
https://doi.org/10.18632/oncotarget.10393 Min Xu, Feifei Qi, Shaosen Zhang, Xuhui Ma, Shan Wang, Chunying Wang, Yan Fu, and Yongzhang Luo
55043-55056

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Metformin increases PDH and suppresses HIF1α under hypoxic conditions and induces cell death in oral squamous cell carcinoma	Metformin increases PDH and suppresses HIF1α under hypoxic conditions and induces cell death in oral squamous cell carcinoma
https://doi.org/10.18632/oncotarget.10842 Talita Antunes Guimarães, Lucyana Conceição Farias, Eliane Sobrinho Santos, Carlos Alberto de Carvalho Fraga, Lissur Azevedo Orsini, Leandro de Freitas Teles, John David Feltenberger, Sabrina Ferreira de Jesus, Marcela Gonçalves de Souza, Sérgio Henrique Sousa Santos, Alfredo Maurício Batista de Paula, Ricardo Santiago Gomez, and André Luiz Sena Guimarães
55057-55068

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Phenotypic and genetic heterogeneity of tumor tissue and circulating tumor cells in patients with metastatic castrationresistant prostate cancer: a report from the PETRUS prospective study	Phenotypic and genetic heterogeneity of tumor tissue and circulating tumor cells in patients with metastatic castrationresistant prostate cancer: a report from the PETRUS prospective study
https://doi.org/10.18632/oncotarget.10396 Christophe Massard, Marianne Oulhen, Sylvestre Le Moulec, Nathalie Auger, Stéphanie Foulon, Aurélie Abou-Lovergne, Fanny Billiot, Alexander Valent, Virginie Marty, Yohann Loriot, Karim Fizazi, Philippe Vielh, and Francoise Farace
55069-55082

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MLN0128 a novel mTOR kinase inhibitor disrupts survival signaling and triggers apoptosis in AML and AML stem/ progenitor cells	MLN0128 a novel mTOR kinase inhibitor disrupts survival signaling and triggers apoptosis in AML and AML stem/ progenitor cells
https://doi.org/10.18632/oncotarget.10397 Zhihong Zeng, Rui-Yu Wang, Yi Hua Qiu, Duncan H. Mak, Kevin Coombes, Suk Young Yoo, Qi Zhang, Katti Jessen, Yi Liu, Christian Rommel, David A. Fruman, Hagop M. Kantarjian, Steven M. Kornblau, Michael Andreeff, and Marina Konopleva
55083-55097

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tumor LINE1 methylation level and colorectal cancer location in relation to patient survival	Tumor LINE1 methylation level and colorectal cancer location in relation to patient survival
https://doi.org/10.18632/oncotarget.10398 Kosuke Mima, Jonathan A. Nowak, Zhi Rong Qian, Yin Cao, Mingyang Song, Yohei Masugi, Yan Shi, Annacarolina da Silva, Mancang Gu, Wanwan Li, Tsuyoshi Hamada, Xuehong Zhang, Kana Wu, Jeffrey A. Meyerhardt, Hideo Baba, Edward L. Giovannucci, Andrew T. Chan, Charles S. Fuchs, Shuji Ogino, and Reiko Nishihara
55098-55109

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Carboxylterminal truncated HBx contributes to invasion and metastasis via deregulating metastasis suppressors in hepatocellular carcinoma	Carboxylterminal truncated HBx contributes to invasion and metastasis via deregulating metastasis suppressors in hepatocellular carcinoma
https://doi.org/10.18632/oncotarget.10399 Weihua Li, Man Li, Dongjiang Liao, Xinpeng Lu, Xia Gu, Qianqian Zhang, Zhixiang Zhang, and Hui Li
55110-55127

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MITF depletion elevates expression levels of ERBB3 receptor and its cognate ligand NRG1beta in melanoma	MITF depletion elevates expression levels of ERBB3 receptor and its cognate ligand NRG1beta in melanoma
https://doi.org/10.18632/oncotarget.10422 Tine N. Alver, Timothy J. Lavelle, Ane S. Longva, Geir F. Øy, Eivind Hovig, and Sigurd L. Bøe
55128-55140

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Targeting αvβ3 and αvβ5 integrins inhibits pulmonary metastasis in an intratibial xenograft osteosarcoma mouse model	Targeting αvβ3 and αvβ5 integrins inhibits pulmonary metastasis in an intratibial xenograft osteosarcoma mouse model
https://doi.org/10.18632/oncotarget.10461 Ana Gvozdenovic, Aleksandar Boro, Daniela Meier, Beata Bode-Lesniewska, Walter Born, Roman Muff, and Bruno Fuchs
55141-55154

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

High expression of intratumoral stromal proteins is associated with chemotherapy resistance in breast cancer	High expression of intratumoral stromal proteins is associated with chemotherapy resistance in breast cancer
https://doi.org/10.18632/oncotarget.10894 Tingting Wang, Supriya Srivastava, Mikael Hartman, Shaik Ahmad Buhari, Ching-Wan Chan, Philip Iau, Lay Wai Khin, Andrea Wong, Sing-Huang Tan, Boon-Cher Goh, and Soo-Chin Lee
55155-55168

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Sexspecific clinicopathological significance of novel Frizzled7 and established MGMT IDH1 biomarkers in glioblastoma	Sexspecific clinicopathological significance of novel Frizzled7 and established MGMT IDH1 biomarkers in glioblastoma
https://doi.org/10.18632/oncotarget.10465 Salveena Schiffgens, Ludwig Wilkens, Alba A. Brandes, Tatiana Meier, Enrico Franceschi, Mario Ermani, Christian Hartmann, Ibrahim Erol Sandalcioglu, and Claudia A. Dumitru
55169-55180

Abstract  |  PDF  |  Full Text  |  How to cite

Serum neuronspecific enolase levels are upregulated in patients with acute lymphoblastic leukemia and are predictive of prognosis	Serum neuronspecific enolase levels are upregulated in patients with acute lymphoblastic leukemia and are predictive of prognosis
https://doi.org/10.18632/oncotarget.10473 Cheng-cheng Liu, Hua Wang, Jing-hua Wang, Liang Wang, Qi-rong Geng, Xiao-qin Chen, and Yue Lu
55181-55190

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

1433ζ and aPKCι synergistically facilitate epithelialmesenchymal transition of cholangiocarcinoma via GSK3β/Snail signaling pathway	1433ζ and aPKCι synergistically facilitate epithelialmesenchymal transition of cholangiocarcinoma via GSK3β/Snail signaling pathway
https://doi.org/10.18632/oncotarget.10483 Yan Yang, Yan Liu, Jun-chuang He, Jian-ming Wang, Peter Schemmer, Chao-qun Ma, Ya-wei Qian, Wei Yao, Jian Zhang, Wei-peng Qi, Yang Fu, Wei Feng, and Tao Yang
55191-55210

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Nomogram and recursive partitioning analysis to predict overall survival in patients with stage IIBIII thoracic esophageal squamous cell carcinoma after esophagectomy	Nomogram and recursive partitioning analysis to predict overall survival in patients with stage IIBIII thoracic esophageal squamous cell carcinoma after esophagectomy
https://doi.org/10.18632/oncotarget.10904 Shufei Yu, Wencheng Zhang, Wenjie Ni, Zefen Xiao, Xin Wang, Zongmei Zhou, Qinfu Feng, Dongfu Chen, Jun Liang, Dekang Fang, Yousheng Mao, Shugeng Gao, Yexiong Li, and Jie He
55211-55221

Abstract  |  PDF  |  Full Text  |  How to cite

Altered phenotypic and functional characteristics of CD3+CD56+ NKTlike cells in human gastric cancer	Altered phenotypic and functional characteristics of CD3+CD56+ NKTlike cells in human gastric cancer
https://doi.org/10.18632/oncotarget.10484 Liu-sheng Peng, Fang-yuan Mao, Yong-liang Zhao, Ting-ting Wang, Na Chen, Jin-yu Zhang, Ping Cheng, Wen-hua Li, Yi-pin Lv, Yong-sheng Teng, Gang Guo, Ping Luo, Weisan Chen, Quan-ming Zou, and Yuan Zhuang
55222-55230

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification of a circulating microRNA signature to distinguish recurrence in breast cancer patients	Identification of a circulating microRNA signature to distinguish recurrence in breast cancer patients
https://doi.org/10.18632/oncotarget.10485 Dezheng Huo, Wendy M. Clayton, Toshio F. Yoshimatsu, Jianjun Chen, and Olufunmilayo I. Olopade
55231-55248

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Metadimensional data integration identifies critical pathways for susceptibility tumorigenesis and progression of endometrial cancer	Metadimensional data integration identifies critical pathways for susceptibility tumorigenesis and progression of endometrial cancer
https://doi.org/10.18632/oncotarget.10509 Runmin Wei, Immaculata De Vivo, Sijia Huang, Xun Zhu, Harvey Risch, Jason H. Moore, Herbert Yu, and Lana X. Garmire
55249-55263

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Somatic mutations predict outcomes of hypomethylating therapy in patients with myelodysplastic syndrome	Somatic mutations predict outcomes of hypomethylating therapy in patients with myelodysplastic syndrome
https://doi.org/10.18632/oncotarget.10526 Seung-Hyun Jung, Yoo-Jin Kim, Seon-Hee Yim, Hye-Jung Kim, Yong-Rim Kwon, Eun-Hye Hur, Bon-Kwan Goo, Yun-Suk Choi, Sug Hyung Lee, Yeun-Jun Chung, and Je-Hwan Lee
55264-55275

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Expression of neural cell adhesion molecule L1 CD171 in neuroectodermal and other tumors: An immunohistochemical study of 5155 tumors and critical evaluation of CD171 prognostic value in gastrointestinal stromal tumors	Expression of neural cell adhesion molecule L1 CD171 in neuroectodermal and other tumors: An immunohistochemical study of 5155 tumors and critical evaluation of CD171 prognostic value in gastrointestinal stromal tumors
https://doi.org/10.18632/oncotarget.10527 Shingo Inaguma, Zengfeng Wang, Jerzy P. Lasota, and Markku M. Miettinen
55276-55289

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

CEACAM6 is upregulated by Helicobacter pylori CagA and is a biomarker for early gastric cancer	CEACAM6 is upregulated by Helicobacter pylori CagA and is a biomarker for early gastric cancer
https://doi.org/10.18632/oncotarget.10528 Rony K. Roy, Michal M. Hoppe, Supriya Srivastava, Animesh Samanta, Neel Sharma, Kar Tong Tan, Henry Yang, Dominic C. Voon, Brendan Pang, Ming Teh, Naoko Murata-Kamiya, Masanori Hatakeyama, Young-Tae Chang, Wei Peng Yong, Yoshiaki Ito, Khek Yu Ho, Patrick Tan, Richie Soong, Phillip H. Koeffler, Khay Guan Yeoh, and Anand D. Jeyasekharan
55290-55301

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Nucleophosmin leukemogenic mutant activates Wnt signaling during zebrafish development	Nucleophosmin leukemogenic mutant activates Wnt signaling during zebrafish development
https://doi.org/10.18632/oncotarget.10878 Elisa Barbieri, Gianluca Deflorian, Federica Pezzimenti, Debora Valli, Marco Saia, Natalia Meani, Alicja M. Gruszka, and Myriam Alcalay
55302-55312

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The human Smoothened inhibitor PF04449913 induces exit from quiescence and loss of multipotent Drosophila hematopoietic progenitor cells	The human Smoothened inhibitor PF04449913 induces exit from quiescence and loss of multipotent Drosophila hematopoietic progenitor cells
https://doi.org/10.18632/oncotarget.10879 Giorgia Giordani, Marilena Barraco, Angela Giangrande, Giovanni Martinelli, Viviana Guadagnuolo, Giorgia Simonetti, Giovanni Perini, and Roberto Bernardoni
55313-55327

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

CD109 is identified as a potential nasopharyngeal carcinoma biomarker using aptamer selected by cellSELEX	CD109 is identified as a potential nasopharyngeal carcinoma biomarker using aptamer selected by cellSELEX
https://doi.org/10.18632/oncotarget.10530 Wenting Jia, Caiping Ren, Lei Wang, Bin Zhu, Wei Jia, Menghui Gao, Fei Zeng, Liang Zeng, Xiaomeng Xia, Xiaobing Zhang, Ting Fu, Shasha Li, Can Du, Xingjun Jiang, Yuxiang Chen, Weihong Tan, Zilong Zhao, and Weidong Liu
55328-55342

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A novel gene expressionbased prognostic scoring system to predict survival in gastric cancer	A novel gene expressionbased prognostic scoring system to predict survival in gastric cancer
https://doi.org/10.18632/oncotarget.10533 Pin Wang, Yunshan Wang, Bo Hang, Xiaoping Zou, and Jian-Hua Mao
55343-55351

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Ranking novel cancer driving synthetic lethal gene pairs using TCGA data	Ranking novel cancer driving synthetic lethal gene pairs using TCGA data
https://doi.org/10.18632/oncotarget.10536 Hao Ye, Xiuhua Zhang, Yunqin Chen, Qi Liu, and Jia Wei
55352-55367

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Incidence and origin of histologically confirmed liver metastases: an explorative casestudy of 23154 patients	Incidence and origin of histologically confirmed liver metastases: an explorative casestudy of 23154 patients
https://doi.org/10.18632/oncotarget.10552 Jannemarie de Ridder, Johannes H.W. de Wilt, Femke Simmer, Lucy Overbeek, Valery Lemmens, and Iris Nagtegaal
55368-55376

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification of biomarkers for pseudo and true progression of GBM based on radiogenomics study	Identification of biomarkers for pseudo and true progression of GBM based on radiogenomics study
https://doi.org/10.18632/oncotarget.10553 Xiaohua Qian, Hua Tan, Jian Zhang, Keqin Liu, Tielin Yang, Maode Wang, Waldemar Debinskie, Weilin Zhao, Michael D. Chan, and Xiaobo Zhou
55377-55394

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MicroRNA fingerprints in juvenile myelomonocytic leukemia JMML identified miR1505p as a tumor suppressor and potential target for treatment	MicroRNA fingerprints in juvenile myelomonocytic leukemia JMML identified miR1505p as a tumor suppressor and potential target for treatment
https://doi.org/10.18632/oncotarget.10577 Pier Paolo Leoncini, Alice Bertaina, Dimitrios Papaioannou, Christian Flotho, Riccardo Masetti, Silvia Bresolin, Giuseppe Menna, Nicola Santoro, Marco Zecca, Giuseppe Basso, Giovanni Nigita, Dario Veneziano, Sara Pagotto, Katia D’Ovidio, Rossella Rota, Adrienne Dorrance, Carlo M. Croce, Charlotte Niemeyer, Franco Locatelli, and Ramiro Garzon
55395-55408

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

CD44v6competent tumor exosomes promote motility invasion and cancerinitiating cell marker expression in pancreatic and colorectal cancer cells	CD44v6competent tumor exosomes promote motility invasion and cancerinitiating cell marker expression in pancreatic and colorectal cancer cells
https://doi.org/10.18632/oncotarget.10580 Zhe Wang, Anja von Au, Martina Schnölzer, Thilo Hackert, and Margot Zöller
55409-55436

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prorenin receptor acts as a potential molecular target for pancreatic ductal adenocarcinoma diagnosis	Prorenin receptor acts as a potential molecular target for pancreatic ductal adenocarcinoma diagnosis
https://doi.org/10.18632/oncotarget.10583 Arivajiagane Arundhathi, Wen-Han Chuang, Jen-Kun Chen, Shin-E Wang, Yi-Ming Shyr, Jiun-Yu Chen, Wei-Neng Liao, Hsin-Wei Chen, Yi-Min Teng, Chiao-Chih Pai, and Chih-Hong Wang
55437-55448

Abstract  |  PDF  |  Full Text  |  How to cite

ABCC224C > T polymorphism is associated with the response to platinum/5Fubased neoadjuvant chemotherapy and better clinical outcomes in advanced gastric cancer patients	ABCC224C > T polymorphism is associated with the response to platinum/5Fubased neoadjuvant chemotherapy and better clinical outcomes in advanced gastric cancer patients
https://doi.org/10.18632/oncotarget.10961 Ziyu Li, Xiaofang Xing, Fei Shan, Shuangxi Li, Zhongwu Li, Aitang Xiao, Zhaodong Xing, Kan Xue, Zhemin Li, Ying Hu, Yongning Jia, Rulin Miao, Lianhai Zhang, Zhaode Bu, Aiwen Wu, and Jiafu Ji
55449-55457

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Thromboxane A2 receptor TBXA2R is a potent survival factor for triple negative breast cancers TNBCs	Thromboxane A2 receptor TBXA2R is a potent survival factor for triple negative breast cancers TNBCs
https://doi.org/10.18632/oncotarget.10969 Katy Orr, Niamh E. Buckley, Paula Haddock, Colin James, Jean-Luc Parent, Stephen McQuaid, and Paul B. Mullan
55458-55472

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Monocytederived factors including PLA2G7 induced by macrophagenasopharyngeal carcinoma cell interaction promote tumor cell invasiveness	Monocytederived factors including PLA2G7 induced by macrophagenasopharyngeal carcinoma cell interaction promote tumor cell invasiveness
https://doi.org/10.18632/oncotarget.10980 Heng Boon Low, Chin Wen Png, Chunwei Li, De Yun Wang, Soon Boon Justin Wong, and Yongliang Zhang
55473-55490

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Insulinlike growth factor binding protein3 links obesity and breast cancer progression	Insulinlike growth factor binding protein3 links obesity and breast cancer progression
https://doi.org/10.18632/oncotarget.10675 Tiffany Scully, Sue M. Firth, Carolyn D. Scott, Hasanthi C. de Silva, John E. Pintar, Tailoi Chan-Ling, Stephen M. Twigg, and Robert C. Baxter
55491-55505

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Upregulation of brainderived neurotrophic factor in advanced gastric cancer contributes to bone metastatic osteolysis by inducing long pentraxin 3	Upregulation of brainderived neurotrophic factor in advanced gastric cancer contributes to bone metastatic osteolysis by inducing long pentraxin 3
https://doi.org/10.18632/oncotarget.10747 Bongkun Choi, Eun-Jin Lee, Min-Kyung Shin, Young Soo Park, Min-Hee Ryu, Sang-Min Kim, Eun-Young Kim, Hyung Keun Lee, and Eun-Ju Chang
55506-55517

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Downregulated pseudogene CTNNAP1 promote tumor growth in human cancer by downregulating its cognate gene CTNNA1 expression	Downregulated pseudogene CTNNAP1 promote tumor growth in human cancer by downregulating its cognate gene CTNNA1 expression
https://doi.org/10.18632/oncotarget.10833 Xiangjian Chen, Hua Zhu, Xiaoli Wu, Xuemeng Xie, Guanli Huang, Xiaoqun Xu, Shi Li, and Chungen Xing
55518-55528

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The application of mRNAbased gene transfer in mesenchymal stem cellmediated cytotoxicity of glioma cells	The application of mRNAbased gene transfer in mesenchymal stem cellmediated cytotoxicity of glioma cells
https://doi.org/10.18632/oncotarget.10835 Xing-Rong Guo, Zhuo-Shun Yang, Xiang-Jun Tang, Dan-Dan Zou, Hui Gui, Xiao-Li Wang, Shi-Nan Ma, Ya-Hong Yuan, Juan Fang, Bin Wang, Li Zhang, Xu-Yong Sun, Garth L. Warnock, Long-Jun Dai, and Han-Jun Tu
55529-55542

Abstract  |  PDF  |  Full Text  |  How to cite

A FASNTGFβ1FASN regulatory loop contributes to high EMT/metastatic potential of cisplatinresistant nonsmall cell lung cancer	A FASNTGFβ1FASN regulatory loop contributes to high EMT/metastatic potential of cisplatinresistant nonsmall cell lung cancer
https://doi.org/10.18632/oncotarget.10837 Li Yang, Fuquan Zhang, Xin Wang, Ying Tsai, Kuang-Hsiang Chuang, Peter C. Keng, Soo Ok Lee, and Yuhchyau Chen
55543-55554

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Targeting hyperactivated DNAPKcs by KU0060648 inhibits glioma progression and enhances temozolomide therapy via suppression of AKT signaling	Targeting hyperactivated DNAPKcs by KU0060648 inhibits glioma progression and enhances temozolomide therapy via suppression of AKT signaling
https://doi.org/10.18632/oncotarget.10864 Tian Lan, Zitong Zhao, Yanming Qu, Mingshan Zhang, Haoran Wang, Zhihua Zhang, Wei Zhou, Xinyi Fan, Chunjiang Yu, Qimin Zhan, and Yongmei Song
55555-55571

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Integrin β3 and CD44 levels determine the effects of the OPNa splicing variant on lung cancer cell growth	Integrin β3 and CD44 levels determine the effects of the OPNa splicing variant on lung cancer cell growth
https://doi.org/10.18632/oncotarget.10865 Shih-Jung Sun, Chun-Chi Wu, Gwo-Tarng Sheu, Hui-Yi Chang, Mei-Yu Chen, Yu-Ying Lin, Cheng-Yen Chuang, Shih-Lan Hsu, and Jinghua Tsai Chang
55572-55584

Abstract  |  PDF  |  Full Text  |  How to cite

YMO1 suppresses invasion and metastasis by inhibiting RhoC signaling and predicts favorable prognosis in hepatocellular carcinoma	YMO1 suppresses invasion and metastasis by inhibiting RhoC signaling and predicts favorable prognosis in hepatocellular carcinoma
https://doi.org/10.18632/oncotarget.10866 Rui-Min Chang, Lei Pei, Feng Fang, Jiang-Feng Xu, Hao Yang, Chao-Hui Zuo, Jian-Hua Zhou, Geng-Qiu Luo, and Lian-Yue Yang
55585-55600

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Decreased expression of FOXF2 as new predictor of poor prognosis in stage I nonsmall cell lung cancer	Decreased expression of FOXF2 as new predictor of poor prognosis in stage I nonsmall cell lung cancer
https://doi.org/10.18632/oncotarget.10876 Peng-Zhou Kong, Guang-Ming Li, Yin Tian, Bin Song, and RuYi Shi
55601-55610

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The associations between MDM4 gene polymorphisms and cancer risk	The associations between MDM4 gene polymorphisms and cancer risk
https://doi.org/10.18632/oncotarget.10877 Ming-Jie Wang, Yong-Jun Luo, Zhi-Yong Shi, Xiao-Liang Xu, Guo-Liang Yao, Rui-Ping Liu, and Hui Zhao
55611-55623

Abstract  |  PDF  |  Full Text  |  How to cite

HypoxiaNOTCH1SOX2 signaling is important for maintaining cancer stem cells in ovarian cancer	HypoxiaNOTCH1SOX2 signaling is important for maintaining cancer stem cells in ovarian cancer
https://doi.org/10.18632/oncotarget.10954 Eun Jin Seo, Dae Kyoung Kim, Il Ho Jang, Eun Jung Choi, Sang Hun Shin, Su In Lee, Sang-Mo Kwon, Ki-Hyung Kim, Dong-Soo Suh, and Jae Ho Kim
55624-55638

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Constitutive gp130 activation rapidly accelerates the transformation of human hepatocytes via an impaired oxidative stress response	Constitutive gp130 activation rapidly accelerates the transformation of human hepatocytes via an impaired oxidative stress response
https://doi.org/10.18632/oncotarget.10956 Denise Heim, Ines Gil-Ibanez, Johannes Herden, Ann Christin Parplys, Kerstin Borgmann, Dirk Schmidt-Arras, Ansgar W. Lohse, Stefan Rose-John, and Henning Wege
55639-55648

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

S18 family of mitochondrial ribosomal proteins: evolutionary history and Gly132 polymorphism in colon carcinoma	S18 family of mitochondrial ribosomal proteins: evolutionary history and Gly132 polymorphism in colon carcinoma
https://doi.org/10.18632/oncotarget.10957 Muhammad Mushtaq, Raja Hashim Ali, Vladimir Kashuba, George Klein, and Elena Kashuba
55649-55662

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

CD24 promoted cancer cell angiogenesis via Hsp90mediated STAT3/VEGF signaling pathway in colorectal cancer	CD24 promoted cancer cell angiogenesis via Hsp90mediated STAT3/VEGF signaling pathway in colorectal cancer
https://doi.org/10.18632/oncotarget.10971 Xinying Wang, Yu Zhang, Yingying Zhao, Yanling Liang, Cheng Xiang, Huanyu Zhou, Hui Zhang, Qiang Zhang, Haitao Qing, Bo Jiang, Huabao Xiong, and Liang Peng
55663-55676

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Epigenetic activation of LY6K predicts the presence of metastasis and poor prognosis in breast carcinoma	Epigenetic activation of LY6K predicts the presence of metastasis and poor prognosis in breast carcinoma
https://doi.org/10.18632/oncotarget.10972 Hyun Kyung Kong, Sae Jeong Park, Ye Sol Kim, Kyoung Min Kim, Hyun-Woo Lee, Hyeok-Gu Kang, Yu Mi Woo, Eun Young Park, Je Yeong Ko, Hiromu Suzuki, Kyung-Hee Chun, Erwei Song, Kyu Yun Jang, and Jong Hoon Park
55677-55689

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Healthy CD4+ T lymphocytes are not affected by targeted therapies against the PI3K/Akt/mTOR pathway in Tcell acute lymphoblastic leukemia	Healthy CD4+ T lymphocytes are not affected by targeted therapies against the PI3K/Akt/mTOR pathway in Tcell acute lymphoblastic leukemia
https://doi.org/10.18632/oncotarget.10984 Ayman A.M. Alameen, Carolina Simioni, Alberto M. Martelli, Giorgio Zauli, Simona Ultimo, James A. McCubrey, Arianna Gonelli, Giorgia Marisi, Paola Ulivi, Silvano Capitani, and Luca M. Neri
55690-55703

Abstract  |  PDF  |  Full Text  |  How to cite

The transmembrane domain of Bcl2α but not its hydrophobic cleft is a critical determinant for efficient IP3 receptor inhibition	The transmembrane domain of Bcl2α but not its hydrophobic cleft is a critical determinant for efficient IP3 receptor inhibition
https://doi.org/10.18632/oncotarget.11005 Hristina Ivanova, Abigael Ritane, Larry Wagner, Tomas Luyten, George Shapovalov, Kirsten Welkenhuyzen, Bruno Seitaj, Giovanni Monaco, Humbert De Smedt, Natalia Prevarskaya, David I. Yule, Jan B. Parys, and Geert Bultynck
55704-55720

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinical Research Papers

Efficacy and safety of cisplatin dexamethasone gemcitabine and pegaspargase DDGP regimen in newly diagnosed advancedstage extranodal natural killer/Tcell lymphoma: interim analysis of a phase 4 study NCT01501149	Efficacy and safety of cisplatin dexamethasone gemcitabine and pegaspargase DDGP regimen in newly diagnosed advancedstage extranodal natural killer/Tcell lymphoma: interim analysis of a phase 4 study NCT01501149
https://doi.org/10.18632/oncotarget.10124 Lei Zhang, Sisi Jia, Yangyang Ma, Ling Li, Xin Li, Xinhua Wang, Xiaorui Fu, Wang Ma, Yanru Qin, Wencai Li, Jingjing Wu, Zhenchang Sun, Xudong Zhang, Feifei Nan, Yu Chang, Zhaoming Li, Dandan Zhang, Guannan Wang, Jiaqin Yan, Liping Su, Jinghua Wang, Hongwei Xue, Ken H. Young, and Mingzhi Zhang
55721-55731

Abstract  |  PDF  |  Full Text  |  How to cite

Chemotherapy plus targeted drugs in conversion therapy for potentially resectable colorectal liver metastases: a metaanalysis	Chemotherapy plus targeted drugs in conversion therapy for potentially resectable colorectal liver metastases: a metaanalysis
https://doi.org/10.18632/oncotarget.9675 Lu Wang, Yinan Sun, Ben Zhao, Huixian Zhang, Qianqian Yu, and Xianglin Yuan
55732-55740

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Pharmacogenomics of platinumbased chemotherapy response in NSCLC: a genotyping study and a pooled analysis	Pharmacogenomics of platinumbased chemotherapy response in NSCLC: a genotyping study and a pooled analysis
https://doi.org/10.18632/oncotarget.9688 Juan Chen, Zhan Wang, Ting Zou, Jiajia Cui, Jiye Yin, Wei Zheng, Wuzhong Jiang, Honghao Zhou, and Zhaoqian Liu
55741-55756

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

TCF21 genetic polymorphisms and breast cancer risk in Chinese women	TCF21 genetic polymorphisms and breast cancer risk in Chinese women
https://doi.org/10.18632/oncotarget.9825 Xueren Gao, Jiaojiao Yang, Mingxi Wang, and Jianqiong Zhang
55757-55764

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Elevated serum Creactive protein level predicts a poor prognosis for recurrent gastric cancer	Elevated serum Creactive protein level predicts a poor prognosis for recurrent gastric cancer
https://doi.org/10.18632/oncotarget.9910 Fanming Kong, Fangfang Gao, Jun Chen, Rongxiu Zheng, Honggen Liu, Xiaojiang Li, Peiying Yang, Geli Liu, and Yingjie Jia
55765-55770

Abstract  |  PDF  |  Full Text  |  How to cite

Reviews

Targeting epithelialmesenchymal transition and cancer stem cells for chemoresistant ovarian cancer	Targeting epithelialmesenchymal transition and cancer stem cells for chemoresistant ovarian cancer
https://doi.org/10.18632/oncotarget.9908 Junli Deng, Li Wang, Hongmin Chen, Jingli Hao, Jie Ni, Lei Chang, Wei Duan, Peter Graham, and Yong Li
55771-55788

Abstract  |  PDF  |  Full Text  |  How to cite

The multifaceted role of lysine acetylation in cancer: prognostic biomarker and therapeutic target	The multifaceted role of lysine acetylation in cancer: prognostic biomarker and therapeutic target
https://doi.org/10.18632/oncotarget.10048 Marta Di Martile, Donatella Del Bufalo, and Daniela Trisciuoglio
55789-55810

Abstract  |  PDF  |  Full Text  |  How to cite

Sulfonation an underexploited area: from skeletal development to infectious diseases and cancer	Sulfonation an underexploited area: from skeletal development to infectious diseases and cancer
https://doi.org/10.18632/oncotarget.10046 Ada W.Y. Leung, Ian Backstrom, and Marcel B. Bally
55811-55827

Abstract  |  PDF  |  Full Text  |  How to cite

Positive and negative functions of B lymphocytes in tumors	Positive and negative functions of B lymphocytes in tumors
https://doi.org/10.18632/oncotarget.10094 Meng Shen, Qian Sun, Jian Wang, Wei Pan, and Xiubao Ren
55828-55839

Abstract  |  PDF  |  Full Text  |  How to cite

Endocannabinoid control of glutamate NMDA receptors: the therapeutic potential and consequences of dysfunction	Endocannabinoid control of glutamate NMDA receptors: the therapeutic potential and consequences of dysfunction
https://doi.org/10.18632/oncotarget.10095 María Rodríguez-Muñoz, Pilar Sánchez-Blázquez, Manuel Merlos, and Javier Garzón-Niño
55840-55862

Abstract  |  PDF  |  Full Text  |  How to cite

Cytoplasmic vacuolization in cell death and survival	Cytoplasmic vacuolization in cell death and survival
https://doi.org/10.18632/oncotarget.10150 Andrey V. Shubin, Ilya V. Demidyuk, Alexey A. Komissarov, Lola M. Rafieva, and Sergey V. Kostrov
55863-55889

Abstract  |  PDF  |  Full Text  |  How to cite

Prognostic value of amphiregulin and epiregulin mRNA expression in metastatic colorectal cancer patients	Prognostic value of amphiregulin and epiregulin mRNA expression in metastatic colorectal cancer patients
https://doi.org/10.18632/oncotarget.10151 Chen Jing, Yang Han Jin, Zhai You, Qian Qiong, and Zhou Jun
55890-55899

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miR497 expression function and clinical application in cancer	miR497 expression function and clinical application in cancer
https://doi.org/10.18632/oncotarget.10152 Gang Yang, Guangbing Xiong, Zhe Cao, Suli Zheng, Lei You, Taiping Zhang, and Yupei Zhao
55900-55911

Abstract  |  PDF  |  Full Text  |  How to cite

A metaanalysis of alcohol consumption and thyroid cancer risk	A metaanalysis of alcohol consumption and thyroid cancer risk
https://doi.org/10.18632/oncotarget.10352 Xiaofei Wang, Wenli Cheng, Jingdong Li, and Jingqiang Zhu
55912-55923

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

FGFR3TACC3 fusion in solid tumors: mini review	FGFR3TACC3 fusion in solid tumors: mini review
https://doi.org/10.18632/oncotarget.10482 Ricardo Costa, Benedito A. Carneiro, Timothy Taxter, Fabio A. Tavora, Aparna Kalyan, Sachin A. Pai, Young Kwang Chae, and Francis J. Giles
55924-55938

Abstract  |  PDF  |  Full Text  |  How to cite

Copyright © 2026 Rapamycin Press LLC dba Impact Journals
Oncotarget ® is a registered trademark of Rapamycin Press LLC
Impact Journals ® is a registered trademark of Rapamycin Press LLC
RAPAMYCIN PRESS ® is a registered trademark of Rapamycin Press LLC