Oncotarget

Vol 14 (2023)

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Table of Contents

Research Papers

Targeting CD74 in B-cell non-Hodgkin lymphoma with the antibody-drug conjugate STRO-001

Targeting CD74 in B-cell non-Hodgkin lymphoma with the antibody-drug conjugate STRO-001

https://doi.org/10.18632/oncotarget.28341

Xiaofan Li, Cristina Abrahams, Abigail Yu, Millicent Embry, Robert Henningsen, Venita DeAlmeida, Shannon Matheny, Toni Kline, Alice Yam, Ryan Stafford, Trevor Hallam, Mark Lupher,  and Arturo Molina
1-13
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Papers

Candidate drugs associated with sensitivity of cancer cell lines with DLST amplification or high mRNA levels

Candidate drugs associated with sensitivity of cancer cell lines with DLST amplification or high mRNA levels

https://doi.org/10.18632/oncotarget.28342

Christina Kuhn, Myriam Boeschen, Manuel Philip, Torsten Schöneberg, Doreen Thor,  and Susanne Horn
14-20
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Corrections

Correction: MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma

Correction: MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma

https://doi.org/10.18632/oncotarget.28336

David King, Xiao Dun Li, Gilberto S. Almeida, Colin Kwok, Polly Gravells, Daniel Harrison, Saoirse Burke, Albert Hallsworth, Yann Jamin, Sally George, Simon P. Robinson, Christopher J. Lord, Evon Poon, Daniel Yeomanson, Louis Chesler,  and Helen E. Bryant
21-22
Correction  |  PDF  |  How to cite

Research Papers

The chromatographic constitution of andiroba oil and its healing effects, compared to the LLLT outcomes, in oral mucositis induced in golden Syrian hamsters: a new treatment option

The chromatographic constitution of andiroba oil and its healing effects, compared to the LLLT outcomes, in oral mucositis induced in golden Syrian hamsters: a new treatment option

https://doi.org/10.18632/oncotarget.28338

Jessica T. Gomes, Ana Márcia V. Wanzeler, Sergio M.A. Júnior, Rosa Helena F. Chaves Soares, Carolina P. de Oliveira, Emanuelle de M. Rodrigues, Bruno M. Soares, Diego D.F.A. Alcantara, Rommel M.R. Burbano,  and Fabrício M. Tuji
23-39
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Research Perspectives

Intraventricular immunovirotherapy; a translational step forward

Intraventricular immunovirotherapy; a translational step forward

https://doi.org/10.18632/oncotarget.28343

Joshua D. Bernstock, Sarah Blitz, Kyung-Don Kang,  and Gregory K. Friedman
40-43
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Corrections

Correction: IGF-1 and hyperglycaemia-induced FOXA1 and IGFBP-2 affect epithelial to mesenchymal transition in prostate epithelial cells

Correction: IGF-1 and hyperglycaemia-induced FOXA1 and IGFBP-2 affect epithelial to mesenchymal transition in prostate epithelial cells

https://doi.org/10.18632/oncotarget.28344

Rehanna Mansor, Jeff Holly, Rachel Barker, Kalina Biernacka, Hanna Zielinska, Anthony Koupparis, Edward Rowe, Jon Oxley, Alex Sewell, Richard M. Martin, Athene Lane, Lucy Hackshaw-McGeagh,  and Claire Perks
44-46
Correction  |  PDF  |  How to cite

Editorial

To be or not to be: the role of CD56 in multiple myeloma

To be or not to be: the role of CD56 in multiple myeloma

https://doi.org/10.18632/oncotarget.28350

Francesca Cottini,  and Don Benson
47-49
PDF  |  How to cite

Retraction

Retraction: Hsa-miR-139-5p inhibits proliferation and causes apoptosis associated with down-regulation of c-Met

Retraction: Hsa-miR-139-5p inhibits proliferation and causes apoptosis associated with down-regulation of c-Met

https://doi.org/10.18632/oncotarget.28329

Chengcao Sun, Ming Sang, Shujun Li, Xiaodong Sun, Cuili Yang, Yongyong Xi, Liang Wang, Feng Zhang, Yongyi Bi, Yunfeng Fu,  and Dejia Li
50-50
Retraction  |  PDF  |  How to cite

Editorial

Permeability and driving force: why is it difficult to control glycolytic flux by blocking lactate transporters?

Permeability and driving force: why is it difficult to control glycolytic flux by blocking lactate transporters?

https://doi.org/10.18632/oncotarget.28351

Wiktoria Blaszczak,  and Pawel Swietach
51-52
PDF  |  How to cite

Corrections

Correction: Synergistic antitumor activity by combining trastuzumab with retinoic acid in HER2 positive human breast cancer cells

Correction: Synergistic antitumor activity by combining trastuzumab with retinoic acid in HER2 positive human breast cancer cells

https://doi.org/10.18632/oncotarget.28345

Fiorella Vanderhoeven, Analía Lourdes Redondo, Ana Laura Martinez, Laura María Vargas-Roig, Angel Matias Sanchez,  and Marina Inés Flamini
53-53
Correction  |  PDF  |  How to cite

Editorial

The role of Kras and canonical Wnt pathways for tumorigenesis of extrahepatic biliary system

The role of Kras and canonical Wnt pathways for tumorigenesis of extrahepatic biliary system

https://doi.org/10.18632/oncotarget.28349

Munemasa Nagao, Akihisa Fukuda,  and Hiroshi Seno
54-56
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Research Papers

Spleen tyrosine kinase/FMS-like tyrosine kinase-3 inhibition in relapsed/refractory B-cell lymphoma, including diffuse large B-cell lymphoma: updated data with mivavotinib (TAK-659/CB-659)

Spleen tyrosine kinase/FMS-like tyrosine kinase-3 inhibition in relapsed/refractory B-cell lymphoma, including diffuse large B-cell lymphoma: updated data with mivavotinib (TAK-659/CB-659)

https://doi.org/10.18632/oncotarget.28352

Leo I. Gordon, Reem Karmali, Jason B. Kaplan, Rakesh Popat, Howard A. Burris III, Silvia Ferrari, Sumit Madan, Manish R. Patel, Giuseppe Gritti, Dima El-Sharkawi, F. Ian Chau, John Radford, Jaime Pérez de Oteyza, Pier Luigi Zinzani, Swaminathan P. Iyer, William Townsend, Harry Miao, Igor Proscurshim, Shining Wang, Shilpi Katyayan, Ying Yuan, Jiaxi Zhu, Kate Stumpo, Yaping Shou, Cecilia Carpio,  and Francesc Bosch
57-70
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Papers

Novel inflammation-combined prognostic index to predict survival outcomes in patients with gastric cancer

Novel inflammation-combined prognostic index to predict survival outcomes in patients with gastric cancer

https://doi.org/10.18632/oncotarget.28353

Noriyuki Hirahara, Takeshi Matsubara, Shunsuke Kaji, Hikota Hayashi, Yohei Sasaki, Koki Kawakami, Ryoji Hyakudomi, Tetsu Yamamoto,  and Yoshitsugu Tajima
71-82
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Corrections

Correction: Separation of low and high grade colon and rectum carcinoma by eukaryotic translation initiation factors 1, 5 and 6

Correction: Separation of low and high grade colon and rectum carcinoma by eukaryotic translation initiation factors 1, 5 and 6

https://doi.org/10.18632/oncotarget.28115

Nicole Golob-Schwarzl, Caroline Schweiger, Carina Koller, Stefanie Krassnig, Margit Gogg-Kamerer, Nadine Gantenbein, Anna M. Toeglhofer, Christina Wodlej, Helmut Bergler, Brigitte Pertschy, Stefan Uranitsch, Magdalena Holter, Amin El-Heliebi, Julia Fuchs, Andreas Punschart, Philipp Stiegler, Marlen Keil, Jens Hoffmann, David Henderson, Hans Lehrach, Christoph Reinhard, Christian Regenbrecht, Rudolf Schicho, Peter Fickert, Sigurd Lax,  and Johannes Haybaeck
83-84
Correction  |  PDF  |  How to cite

Research Papers

Everolimus downregulates STAT3/HIF-1α/VEGF pathway to inhibit angiogenesis and lymphangiogenesis in TP53 mutant head and neck squamous cell carcinoma (HNSCC)

Everolimus downregulates STAT3/HIF-1α/VEGF pathway to inhibit angiogenesis and lymphangiogenesis in TP53 mutant head and neck squamous cell carcinoma (HNSCC)

https://doi.org/10.18632/oncotarget.28355

Md Maksudul Alam, Janmaris Marin Fermin, Mark Knackstedt, Mackenzie J. Noonan, Taylor Powell, Landon Goodreau, Emily K. Daniel, Xiaohua Rong, Tara Moore-Medlin, Alok R. Khandelwal,  and Cherie-Ann O. Nathan
85-95
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Perspectives

The immunoregulatory protein CD200 as a potentially lucrative yet elusive target for cancer therapy

The immunoregulatory protein CD200 as a potentially lucrative yet elusive target for cancer therapy

https://doi.org/10.18632/oncotarget.28354

Anqi Shao,  and David M. Owens
96-103
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Corrections

Correction: KHSRP-bound small nucleolar RNAs associate with promotion of cell invasiveness and metastasis of pancreatic cancer

Correction: KHSRP-bound small nucleolar RNAs associate with promotion of cell invasiveness and metastasis of pancreatic cancer

https://doi.org/10.18632/oncotarget.28361

Keisuke Taniuchi,  and Mitsunari Ogasawara
104-104
Correction  |  PDF  |  How to cite

Research Perspectives

WNT-pathway medulloblastoma: what constitutes low-risk and how low can one go?

WNT-pathway medulloblastoma: what constitutes low-risk and how low can one go?

https://doi.org/10.18632/oncotarget.28360

Shakthivel Mani, Abhishek Chatterjee, Archya Dasgupta, Neelam Shirsat, Sridhar Epari, Girish Chinnaswamy,  and Tejpal Gupta
105-110
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Research Papers

The “extreme phenotype approach” applied to male breast cancer allows the identification of rare variants of ATR as potential breast cancer susceptibility alleles

The “extreme phenotype approach” applied to male breast cancer allows the identification of rare variants of ATR as potential breast cancer susceptibility alleles

https://doi.org/10.18632/oncotarget.28358

Martin Chevarin, Diana Alcantara, Juliette Albuisson, Marie-Agnès Collonge-Rame, Céline Populaire, Zohair Selmani, Amandine Baurand, Caroline Sawka, Geoffrey Bertolone, Patrick Callier, Yannis Duffourd, Philippe Jonveaux, Yves-Jean Bignon, Isabelle Coupier, François Cornelis, Christophe Cordier, Monique Mozelle-Nivoix, Jean-Baptiste Rivière, Paul Kuentz, Christel Thauvin, Romain Boidot, François Ghiringhelli, Marc O'Driscoll, Laurence Faivre,  and Sophie Nambot
111-125
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Addendum

Addendum: Successful administration of sequential TVEC and pembrolizumab followed by Temozolomide in immunotherapy refractory intracranial metastatic melanoma with acquired B2M mutation

Addendum: Successful administration of sequential TVEC and pembrolizumab followed by Temozolomide in immunotherapy refractory intracranial metastatic melanoma with acquired B2M mutation

https://doi.org/10.18632/oncotarget.28365

Karam Khaddour, Joshua Dowling, Jiayi Huang, Martha Council, David Chen, Lynn Cornelius, Tanner Johanns, Sonika Dahiya,  and George Ansstas
126-126
Addendum  |  PDF  |  How to cite

Editorial

Unveiling the non-canonical functions of EZH2 in prostate cancer

Unveiling the non-canonical functions of EZH2 in prostate cancer

https://doi.org/10.18632/oncotarget.28357

Yang Yi, Yanqiang Li, Kaifu Chen,  and Qi Cao
127-128
PDF  |  How to cite  |  Press Release

Corrections

Correction: Biological evaluation of pyrazolyl-urea and dihydro-imidazo-pyrazolyl-urea derivatives as potential anti-angiogenetic agents in the treatment of neuroblastoma

Correction: Biological evaluation of pyrazolyl-urea and dihydro-imidazo-pyrazolyl-urea derivatives as potential anti-angiogenetic agents in the treatment of neuroblastoma

https://doi.org/10.18632/oncotarget.28346

Barbara Marengo, Elda Meta, Chiara Brullo, Chiara De Ciucis, Renata Colla, Andrea Speciale, Ombretta Garbarino, Olga Bruno,  and Cinzia Domenicotti
129-130
Correction  |  PDF  |  How to cite

Addendum

Addendum: Prognostic significance of isochromosome 17q in hematologic malignancies

Addendum: Prognostic significance of isochromosome 17q in hematologic malignancies

https://doi.org/10.18632/oncotarget.28295

Dorota Koczkodaj, Justyna Muzyka-Kasietczuk, Sylwia Chocholska,  and Monika Podhorecka
131-131
Addendum  |  PDF  |  How to cite

Editorial

Unlocking the potential of molecular-driven stratification for osteosarcoma treatment and prognosis

Unlocking the potential of molecular-driven stratification for osteosarcoma treatment and prognosis

https://doi.org/10.18632/oncotarget.28364

Gaël Moquin-Beaudry, Maria Eugenia Marques da Costa, Nathalie Gaspar,  and Antonin Marchais
132-132
PDF  |  How to cite  |  Press Release

Research Papers

Oncogenic driver FGFR3-TACC3 requires five coiled-coil heptads for activation and disulfide bond formation for stability

Oncogenic driver FGFR3-TACC3 requires five coiled-coil heptads for activation and disulfide bond formation for stability

https://doi.org/10.18632/oncotarget.28359

Clark G. Wang, Malalage N. Peiris, April N. Meyer, Katelyn N. Nelson,  and Daniel J. Donoghue
133-145
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial Perspective

Leakage? or Secretion? unconventional protein secretion in cancer

Leakage? or Secretion? unconventional protein secretion in cancer

https://doi.org/10.18632/oncotarget.28368

Kohji Yamada,  and Kiyotsugu Yoshida
146-147
PDF  |  How to cite

Corrections

Correction: Suppression of PKC causes oncogenic stress for triggering apoptosis in cancer cells

Correction: Suppression of PKC causes oncogenic stress for triggering apoptosis in cancer cells

https://doi.org/10.18632/oncotarget.28251

Suthakar Ganapathy, Bo Peng, Ling Shen, Tianqi Yu, Jean Lafontant, Ping Li, Rui Xiong, Alexandros Makriyannis,  and Changyan Chen
148-148
Correction  |  PDF  |  How to cite

Addendum

Addendum: Melatonin increases overall survival of prostate cancer patients with poor prognosis after combined hormone radiation treatment

Addendum: Melatonin increases overall survival of prostate cancer patients with poor prognosis after combined hormone radiation treatment

https://doi.org/10.18632/oncotarget.28363

Gennady M. Zharinov, Oleg A. Bogomolov, Irina V. Chepurnaya, Natalia Yu. Neklasova,  and Vladimir N. Anisimov
149-149
Addendum  |  PDF  |  How to cite

Editorial

Mitochondria engage the integrated stress response to promote tumor growth

Mitochondria engage the integrated stress response to promote tumor growth

https://doi.org/10.18632/oncotarget.28372

Dillon P. Boulton,  and M. Cecilia Caino
150-152
PDF  |  How to cite  |  Press Release

Reviews

What is hemoglobin, albumin, lymphocyte, platelet (HALP) score? A comprehensive literature review of HALP’s prognostic ability in different cancer types

What is hemoglobin, albumin, lymphocyte, platelet (HALP) score? A comprehensive literature review of HALP’s prognostic ability in different cancer types

https://doi.org/10.18632/oncotarget.28367

Christian Mark Farag, Ryan Antar, Sinan Akosman, Matthew Ng,  and Michael J. Whalen
153-172
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Retraction

Retraction: Methylation-induced downregulation and tumor suppressive role of microRNA-29b in gastric cancer through targeting LASP1

Retraction: Methylation-induced downregulation and tumor suppressive role of microRNA-29b in gastric cancer through targeting LASP1

https://doi.org/10.18632/oncotarget.28381

Hui Li, Guoqing Liu, Ke Pan, Xiongying Miao,  and Yong Xie
173-173
Retraction  |  PDF  |  How to cite

Editorial Perspective

C/EBPβ cooperates with MYB to maintain the oncogenic program of AML cells

C/EBPβ cooperates with MYB to maintain the oncogenic program of AML cells

https://doi.org/10.18632/oncotarget.28377

Karl-Heinz Klempnauer
174-177
PDF  |  How to cite

Research Papers

Genomic landscape of metastatic breast cancer (MBC) patients with methylthioadenosine phosphorylase (MTAP) loss

Genomic landscape of metastatic breast cancer (MBC) patients with methylthioadenosine phosphorylase (MTAP) loss

https://doi.org/10.18632/oncotarget.28376

Maroun Bou Zerdan, Prashanth Ashok Kumar, Elio Haroun, Nimisha Srivastava, Jeffrey Ross,  and Abirami Sivapiragasam
178-187
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Corrections

Correction: UBE2T knockdown inhibits gastric cancer progression

Correction: UBE2T knockdown inhibits gastric cancer progression

https://doi.org/10.18632/oncotarget.28356

Changjiang Luo, Yunyi Yao, Zeyuan Yu, Huinian Zhou, Lingyun Guo, Junqiang Zhang, Hongtai Cao, Genyuan Zhang, Yumin Li,  and Zuoyi Jiao
188-189
Correction  |  PDF  |  How to cite

Editorial

Proof-of-principle: targeted childhood leukemia prevention

Proof-of-principle: targeted childhood leukemia prevention

https://doi.org/10.18632/oncotarget.28371

César Cobaleda, Manuel Ramírez-Orellana, Carolina Vicente-Dueñas, Andreas Weiss, Kim E. Nichols,  and Isidro Sánchez-García
190-192
PDF  |  How to cite

Reviews

Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells

Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells

https://doi.org/10.18632/oncotarget.28382

Mikhail V. Blagosklonny
193-206
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

Impact of cortactin in cancer progression on Wnt5a/ROR1 signaling pathway

Impact of cortactin in cancer progression on Wnt5a/ROR1 signaling pathway

https://doi.org/10.18632/oncotarget.28386

Kamrul Hasan,  and Thomas J. Kipps
207-209
PDF  |  How to cite  |  Press Release

Corrections

Correction: Increased expression of long non-coding RNA CCEPR is associated with poor prognosis and promotes tumorigenesis in urothelial bladder carcinoma

Correction: Increased expression of long non-coding RNA CCEPR is associated with poor prognosis and promotes tumorigenesis in urothelial bladder carcinoma

https://doi.org/10.18632/oncotarget.28347

Yonghao Zhan, Yifan Li, Bao Guan, Xiaoying Chen, Zhicong Chen, Anbang He, Shiming He, Yanqing Gong, Ding Peng, Yuchen Liu, Zhiming Cai, Xuesong Li,  and Liqun Zhou
210-210
Correction  |  PDF  |  How to cite

Editorial Perspective

Cancer-associated fibroblasts: challenges and opportunities

Cancer-associated fibroblasts: challenges and opportunities

https://doi.org/10.18632/oncotarget.28385

Hossein Tavana,  and Gary D. Luker
211-214
PDF  |  How to cite  |  Press Release

Corrections

Correction: Annexin A13 promotes tumor cell invasion in vitro and is associated with metastasis in human colorectal cancer

Correction: Annexin A13 promotes tumor cell invasion in vitro and is associated with metastasis in human colorectal cancer

https://doi.org/10.18632/oncotarget.28247

Guozhong Jiang, Pengju Wang, Weiwei Wang, Wencai Li, Liping Dai,  and Kuisheng Chen
215-215
Correction  |  PDF  |  How to cite

Editorial

Therapy drives genomic evolution in metastatic cancer

Therapy drives genomic evolution in metastatic cancer

https://doi.org/10.18632/oncotarget.28379

Ditte S. Christensen,  and Nicolai J. Birkbak
216-218
PDF  |  How to cite

Research Papers

Attenuation of cancer proliferation by suppression of glypican-1 and its pleiotropic effects in neoplastic behavior

Attenuation of cancer proliferation by suppression of glypican-1 and its pleiotropic effects in neoplastic behavior

https://doi.org/10.18632/oncotarget.28388

Fang Cheng, Victor Chérouvrier Hansson, Grigorios Georgolopoulos,  and Katrin Mani
219-235
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Editorial Perspective

Genetic modifiers of p53: opportunities for breast cancer therapies

Genetic modifiers of p53: opportunities for breast cancer therapies

https://doi.org/10.18632/oncotarget.28387

Prabin Dhangada Majhi, Aman Sharma,  and D. Joseph Jerry
236-241
PDF  |  How to cite

Retraction

Retraction: Overexpression of NR4A1 is associated with tumor recurrence and poor survival in non-small-cell lung carcinoma

Retraction: Overexpression of NR4A1 is associated with tumor recurrence and poor survival in non-small-cell lung carcinoma

https://doi.org/10.18632/oncotarget.28396

Bing Zhu, Jian-Ru Yang, Yang Jia, Pei Zhang, Lin Shen, Xiao-Long Li, Jing Li,  and Bing Wang
242-242
Retraction  |  PDF  |  How to cite

Research Papers

Polyisoprenylated cysteinyl amide inhibitors deplete singly polyisoprenylated monomeric G-proteins in lung and breast cancer cell lines

Polyisoprenylated cysteinyl amide inhibitors deplete singly polyisoprenylated monomeric G-proteins in lung and breast cancer cell lines

https://doi.org/10.18632/oncotarget.28390

Nada Tawfeeq, Jassy Mary S. Lazarte, Yonghao Jin, Matthew D. Gregory,  and Nazarius S. Lamango
243-257
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Editorial

Neutrophil PAD4: how does it function in cancer beyond promoting NETosis?

Neutrophil PAD4: how does it function in cancer beyond promoting NETosis?

https://doi.org/10.18632/oncotarget.28369

Laura Garcia-Gerique,  and Yulia Nefedova
258-260
PDF  |  How to cite

Research Papers

Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-β-dependent cell metabolism in human lung adenocarcinoma A549 cells

Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-β-dependent cell metabolism in human lung adenocarcinoma A549 cells

https://doi.org/10.18632/oncotarget.27728

Wataru Arai, Takumi Konno, Takayuki Kohno, Yuki Kodera, Mitsuhiro Tsujiwaki, Yuma Shindo, Hirofumi Chiba, Masahiro Miyajima, Yuji Sakuma, Atsushi Watanabe,  and Takashi Kojima
261-275
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Editorial

p53 protects against formation of extrahepatic biliary precancerous lesions in the context of oncogenic Kras

p53 protects against formation of extrahepatic biliary precancerous lesions in the context of oncogenic Kras

https://doi.org/10.18632/oncotarget.28380

Munemasa Nagao, Kenta Mizukoshi, Shinnosuke Nakayama, Mio Namikawa, Yukiko Hiramatsu, Takahisa Maruno, Yuki Nakanishi, Tatsuaki Tsuruyama, Akihisa Fukuda,  and Hiroshi Seno
276-279
PDF  |  How to cite

Corrections

Correction: YB-1 regulates tumor growth by promoting MACC1/c-Met pathway in human lung adenocarcinoma

Correction: YB-1 regulates tumor growth by promoting MACC1/c-Met pathway in human lung adenocarcinoma

https://doi.org/10.18632/oncotarget.28393

Tao Guo, Shilei Zhao, Peng Wang, Xiaoyuan Xue, Yan Zhang, Mengying Yang, Nan Li, Zhuoshi Li, Lingzhi Xu, Lei Jiang, Lei Zhao, Patrick C. Ma, Rafael Rosell, Jinxiu Li,  and Chundong Gu
280-280
Correction  |  PDF  |  How to cite

Editorial

Impact of SHP2 tyrosine phosphorylation on the development of acquired resistance to allosteric SHP2 inhibitors

Impact of SHP2 tyrosine phosphorylation on the development of acquired resistance to allosteric SHP2 inhibitors

https://doi.org/10.18632/oncotarget.28392

Giulia Franciosa,  and Jesper V. Olsen
281-283
PDF  |  How to cite

Reviews

Crosstalk between triple negative breast cancer and microenvironment

Crosstalk between triple negative breast cancer and microenvironment

https://doi.org/10.18632/oncotarget.28397

Karly Smrekar, Artem Belyakov,  and Kideok Jin
284-293
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Retraction

Retraction: Significance of B10 cell in patients with thymoma complicated with myasthenia gravis

Retraction: Significance of B10 cell in patients with thymoma complicated with myasthenia gravis

https://doi.org/10.18632/oncotarget.28160

Yang Lu, Fanjie Meng, Yang Yang, Lan Li, Donghao Wang, Yuantao Cui, Shangwen Dong,  and Wanhua Wang
294-294
Retraction  |  PDF  |  How to cite

Editorial

Tumor necroptosis promotes metastasis through modulating the interplay between tumor and host immunity

Tumor necroptosis promotes metastasis through modulating the interplay between tumor and host immunity

https://doi.org/10.18632/oncotarget.28404

Zhaoshan Liu, Swati Choksi,  and Zheng-Gang Liu
295-296
PDF  |  How to cite  |  Press Release

Editorial Perspective

EGFR endocytosis: more than meets the eye

EGFR endocytosis: more than meets the eye

https://doi.org/10.18632/oncotarget.28400

Aysegul Sapmaz,  and Ayse Elif Erson-Bensan
297-301
PDF  |  How to cite

Research Papers

A phase I trial of riluzole and sorafenib in patients with advanced solid tumors: CTEP #8850

A phase I trial of riluzole and sorafenib in patients with advanced solid tumors: CTEP #8850

https://doi.org/10.18632/oncotarget.28403

Kristen R. Spencer, Daniella E. Portal, Joseph Aisner, Mark N. Stein, Jyoti Malhotra, Weichung Shih, Nancy Chan, Ann W. Silk, Shridar Ganesan, Susan Goodin, Murugesan Gounder, Hongxia Lin, Jiadong Li, Robert Cerchio, Christina Marinaro, Suzie Chen,  and Janice M. Mehnert
302-315
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Corrections

Correction: Calcitonin receptor is required for T-antigen-induced prostate carcinogenesis

Correction: Calcitonin receptor is required for T-antigen-induced prostate carcinogenesis

https://doi.org/10.18632/oncotarget.28394

Ajay Kale, Afaf Aldahish,  and Girish Shah
316-316
Correction  |  PDF  |  How to cite

Editorial

The nuclear envelope and metastasis

The nuclear envelope and metastasis

https://doi.org/10.18632/oncotarget.28375

Emily Hansen,  and James M. Holaska
317-320
PDF  |  How to cite

Research Perspectives

Adopted neoplastic cells and the consequences of their existence

Adopted neoplastic cells and the consequences of their existence

https://doi.org/10.18632/oncotarget.28408

Yuri Lazebnik
321-341
Abstract  |  PDF  |  Full Text  |  How to cite

Research Perspectives

Cancer prevention with rapamycin

Cancer prevention with rapamycin

https://doi.org/10.18632/oncotarget.28410

Mikhail V. Blagosklonny
342-350
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers

Importance of carbohydrate antigen (CA 19-9) and carcinoembrionic antigen (CEA) in the prognosis of patients with duodenal adenocarcinoma: a retrospective single-institution cohort study

Importance of carbohydrate antigen (CA 19-9) and carcinoembrionic antigen (CEA) in the prognosis of patients with duodenal adenocarcinoma: a retrospective single-institution cohort study

https://doi.org/10.18632/oncotarget.28406

Ellery Altshuler, Raymond Richhart, William King, Mahmoud Aryan, Akash Mathavan, Akshay Mathavan, Keegan Hones, Daniel F. Leach III, Logan Pucci, Joshua Riklan, Pat Haley, Ilyas Sahin, Brian Ramnaraign, Sherise Rogers, Ibrahim Nassour, Steven Hughes, Thomas J. George,  and Jesus Fabregas
351-357
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Research Perspectives

Crossroads: the role of biomarkers in the management of lumps in the breast

Crossroads: the role of biomarkers in the management of lumps in the breast

https://doi.org/10.18632/oncotarget.28402

Georg F. Weber
358-362
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release  |  Video Interview

Retraction

Retraction: LncRNA NEAT1 enhances the radio-resistance of cervical cancer via miR-193b-3p/CCND1 axis

Retraction: LncRNA NEAT1 enhances the radio-resistance of cervical cancer via miR-193b-3p/CCND1 axis

https://doi.org/10.18632/oncotarget.28416

Dongmei Han, Jianfeng Wang,  and Guanghui Cheng
363-363
Retraction  |  PDF  |  How to cite

Editorial

The critical immune basis for differential responses to immunotherapy in primary versus metastatic pancreatic cancer

The critical immune basis for differential responses to immunotherapy in primary versus metastatic pancreatic cancer

https://doi.org/10.18632/oncotarget.28373

Brian Diskin, Sarah Schwartz,  and George Miller
364-365
PDF  |  How to cite

Research Papers

Differential silencing of STAT3 isoforms leads to changes in STAT3 activation

Differential silencing of STAT3 isoforms leads to changes in STAT3 activation

https://doi.org/10.18632/oncotarget.28412

Inbal Shamir, Ilan Tsarfaty, Gidi Paret,  and Yael Nevo-Caspi
366-376
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Perspectives

Disruption of retinol-mediated IL-6 expression in colon cancer-associated fibroblasts: new perspectives on the role of vitamin A metabolism

Disruption of retinol-mediated IL-6 expression in colon cancer-associated fibroblasts: new perspectives on the role of vitamin A metabolism

https://doi.org/10.18632/oncotarget.28399

Romain Villéger, Marina Chulkina, Randy C. Mifflin, Don W. Powell,  and Irina V. Pinchuk
377-381
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

A balancing act: how whole-genome doubling and aneuploidy interact in human cancer

A balancing act: how whole-genome doubling and aneuploidy interact in human cancer

https://doi.org/10.18632/oncotarget.28374

Kavya Prasad,  and Uri Ben-David
382-383
PDF  |  How to cite

Reviews

Systemic AL amyloidosis: current approach and future direction

Systemic AL amyloidosis: current approach and future direction

https://doi.org/10.18632/oncotarget.28415

Maroun Bou Zerdan, Lewis Nasr, Farhan Khalid, Sabine Allam, Youssef Bouferraa, Saba Batool, Muhammad Tayyeb, Shubham Adroja, Mahinbanu Mammadii, Faiz Anwer, Shahzad Raza,  and Chakra P. Chaulagain
384-394
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

AGO2 in T-prolymphocytic leukemia: its canonical and non-canonical deregulation and function

AGO2 in T-prolymphocytic leukemia: its canonical and non-canonical deregulation and function

https://doi.org/10.18632/oncotarget.28378

Till Braun, Hanna Klepzig,  and Marco Herling
395-397
PDF  |  How to cite

Retraction

Retraction: Overexpression of microRNA-132 enhances the radiosensitivity of cervical cancer cells by down-regulating Bmi-1

Retraction: Overexpression of microRNA-132 enhances the radiosensitivity of cervical cancer cells by down-regulating Bmi-1

https://doi.org/10.18632/oncotarget.28413

Gui-Feng Liu, Shu-Hua Zhang, Xue-Feng Li, Li-Yan Cao, Zhan-Zhao Fu,  and Shao-Nan Yu
398-398
Retraction  |  PDF  |  How to cite

Research Perspectives

Using cancer proteomics data to identify gene candidates for therapeutic targeting

Using cancer proteomics data to identify gene candidates for therapeutic targeting

https://doi.org/10.18632/oncotarget.28420

Diana Monsivais, Sydney E. Parks, Darshan S. Chandrashekar, Sooryanarayana Varambally,  and Chad J. Creighton
399-412
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

From the groin to the brain: a transfemoral path to blood-brain barrier opening

From the groin to the brain: a transfemoral path to blood-brain barrier opening

https://doi.org/10.18632/oncotarget.28414

Thomas C. Chen, Weijun Wang,  and Axel H. Schönthal
413-416
PDF  |  How to cite

Corrections

Correction: Connexin 43 expression is associated with increased malignancy in prostate cancer cell lines and functions to promote migration

Correction: Connexin 43 expression is associated with increased malignancy in prostate cancer cell lines and functions to promote migration

https://doi.org/10.18632/oncotarget.28411

Ao Zhang, Masahiro Hitomi, Noah Bar-Shain, Zafardjan Dalimov, Leigh Ellis, Kiran K. Velpula, Gail C. Fraizer, Robert G. Gourdie,  and Justin D. Lathia
417-418
Correction  |  PDF  |  How to cite

Research Perspectives

Targeting cellular respiration as a therapeutic strategy in glioblastoma

Targeting cellular respiration as a therapeutic strategy in glioblastoma

https://doi.org/10.18632/oncotarget.28424

Enyuan Shang, Trang Thi Thu Nguyen, Mike-Andrew Westhoff, Georg Karpel-Massler,  and Markus D. Siegelin
419-425
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers

Human LY6 gene family: potential tumor-associated antigens and biomarkers of prognosis in uterine corpus endometrial carcinoma

Human LY6 gene family: potential tumor-associated antigens and biomarkers of prognosis in uterine corpus endometrial carcinoma

https://doi.org/10.18632/oncotarget.28409

Luke A. Rathbun, Anthony M. Magliocco,  and Anil K. Bamezai
426-437
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Addendum

Addendum: Newly diagnosed papillary craniopharyngioma with BRAF V600E mutation treated with single-agent selective BRAF inhibitor dabrafenib: a case report

Addendum: Newly diagnosed papillary craniopharyngioma with BRAF V600E mutation treated with single-agent selective BRAF inhibitor dabrafenib: a case report

https://doi.org/10.18632/oncotarget.28428

Mayank Rao, Meenakshi Bhattacharjee, Scott Shepard,  and Sigmund Hsu
438-438
Addendum  |  PDF  |  How to cite

Research Perspectives

HER3- A key survival pathway and an emerging therapeutic target in metastatic colorectal cancer and pancreatic ductal adenocarcinoma

HER3- A key survival pathway and an emerging therapeutic target in metastatic colorectal cancer and pancreatic ductal adenocarcinoma

https://doi.org/10.18632/oncotarget.28421

Omkar Desai,  and Rui Wang
439-443
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

Targeting H3K27me3 loss in pediatric brain tumors - a perspective on epigenetically guided cancer therapy

Targeting H3K27me3 loss in pediatric brain tumors - a perspective on epigenetically guided cancer therapy

https://doi.org/10.18632/oncotarget.28427

Michael Goldstein
444-447
PDF  |  How to cite

Corrections

Correction: A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling

Correction: A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling

https://doi.org/10.18632/oncotarget.28430

Stephan J. Matissek, Mona Karbalivand, Weiguo Han, Ava Boutilier, Estefania Yzar-Garcia, Laura L. Kehoe, Devin Storm Gardner, Adam Hage, Krista Fleck, Vicki Jeffers, Ricardo Rajsbaum,  and Sherine F. Elsawa
448-448
Correction  |  PDF  |  How to cite

Addendum

Addendum: Histological and molecular analysis of a progressive diffuse intrinsic pontine glioma and synchronous metastatic lesions: a case report

Addendum: Histological and molecular analysis of a progressive diffuse intrinsic pontine glioma and synchronous metastatic lesions: a case report

https://doi.org/10.18632/oncotarget.28286

Javad Nazarian, Gary E. Mason, Cheng Ying Ho, Eshini Panditharatna, Madhuri Kambhampati, L. Gilbert Vezina, Roger J. Packer,  and Eugene I. Hwang
449-449
Addendum  |  PDF  |  How to cite

Research Papers

Development and implementation of an automated and highly accurate reporting process for NGS-based clonality testing

Development and implementation of an automated and highly accurate reporting process for NGS-based clonality testing

https://doi.org/10.18632/oncotarget.28429

Sean T. Glenn, Phillip M. Galbo Jr., Jesse D. Luce, Kiersten Marie Miles, Prashant K. Singh, Manuel J. Glynias,  and Carl Morrison
450-461
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Editorial

The molecular dialogue between the tumor cells and fibroblasts

The molecular dialogue between the tumor cells and fibroblasts

https://doi.org/10.18632/oncotarget.28405

Ramesh Butti,  and Gopal C. Kundu
462-463
PDF  |  How to cite  |  Video Interview

Corrections

Correction: miR-29a-3p suppresses cell proliferation and migration by downregulating IGF1R in hepatocellular carcinoma

Correction: miR-29a-3p suppresses cell proliferation and migration by downregulating IGF1R in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.28398

Xiao Wang, Shasha Liu, Ling Cao, Tengfei Zhang, Dongli Yue, Liping Wang, Yu Ping, Qianyi He, Chaoqi Zhang, Meng Wang, Xinfeng Chen, Qun Gao, Dan Wang, Zhen Zhang, Fei Wang, Li Yang, Jieyao Li, Lan Huang, Bin Zhang,  and Yi Zhang
464-465
Correction  |  PDF  |  How to cite

Research Papers

G-protein-coupled receptor 141 mediates breast cancer proliferation and metastasis by regulating oncogenic mediators and the p-mTOR/p53 axis

G-protein-coupled receptor 141 mediates breast cancer proliferation and metastasis by regulating oncogenic mediators and the p-mTOR/p53 axis

https://doi.org/10.18632/oncotarget.28433

Monalisa Parija, Amit K. Adhya,  and Sandip K. Mishra
466-480
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Corrections

Correction: Complement inhibitor CSMD1 acts as tumor suppressor in human breast cancer

Correction: Complement inhibitor CSMD1 acts as tumor suppressor in human breast cancer

https://doi.org/10.18632/oncotarget.28426

Astrid Escudero-Esparza, Michael Bartoschek, Chrysostomi Gialeli, Marcin Okroj, Sioned Owen, Karin Jirström, Akira Orimo, Wen G. Jiang, Kristian Pietras,  and Anna M. Blom
481-482
Correction  |  PDF  |  How to cite

Editorial

GBP3-STING interaction in glioblastoma coordinates autophagy, anti-oxidative, and DNA repair programs in response to temozolomide

GBP3-STING interaction in glioblastoma coordinates autophagy, anti-oxidative, and DNA repair programs in response to temozolomide

https://doi.org/10.18632/oncotarget.28370

Jun Ma, Ziyu Wang, Clark C. Chen,  and Ming Li
483-484
PDF  |  How to cite

Research Papers

Role of creatine shuttle in colorectal cancer cells

Role of creatine shuttle in colorectal cancer cells

https://doi.org/10.18632/oncotarget.28436

Mayu Kita, Rina Fujiwara-Tani, Shingo Kishi, Shiori Mori, Hitoshi Ohmori, Chie Nakashima, Kei Goto, Takamitsu Sasaki, Kiyomu Fujii, Isao Kawahara, Ujjal Kumar Bhawal, Yi Luo,  and Hiroki Kuniyasu
485-501
Abstract  |  PDF  |  Full Text  |  How to cite

Addendum

Addendum: Sustained response of three pediatric BRAFV600E mutated high-grade gliomas to combined BRAF and MEK inhibitor therapy

Addendum: Sustained response of three pediatric BRAFV600E mutated high-grade gliomas to combined BRAF and MEK inhibitor therapy

https://doi.org/10.18632/oncotarget.28445

Stephanie A. Toll, Hung N. Tran, Jennifer Cotter, Alexander R. Judkins, Benita Tamrazi, Jaclyn A. Biegel, Girish Dhall, Nathan J. Robison, Kaaren Waters, Palak Patel, Robert Cooper,  and Ashley S. Margol
502-502
Addendum  |  PDF  |  How to cite

Research Perspectives

Targeting the Src N-terminal regulatory element in cancer

Targeting the Src N-terminal regulatory element in cancer

https://doi.org/10.18632/oncotarget.28434

Betlem Mezquita, Marjorie Reyes-Farias,  and Miquel Pons
503-513
Abstract  |  PDF  |  Full Text  |  How to cite

Editorial

Latest updates on MET targeted therapy for EXON 14 mutations in lung cancer

Latest updates on MET targeted therapy for EXON 14 mutations in lung cancer

https://doi.org/10.18632/oncotarget.28419

Mira Al Jaberi, Wolfgang Clough,  and Samir Dalia
514-514
PDF  |  How to cite

Addendum

Addendum: ROS1-GOPC/FIG: a novel gene fusion in hepatic angiosarcoma

Addendum: ROS1-GOPC/FIG: a novel gene fusion in hepatic angiosarcoma

https://doi.org/10.18632/oncotarget.28448

Eric I. Marks, Sahithi Pamarthy, Don Dizon, Ari Birnbaum, Evgeny Yakirevich, Howard Safran,  and Benedito A. Carneiro
515-515
Addendum  |  PDF  |  How to cite

Retraction

Retraction: Inhibition of microRNA-218 reduces HIF-1α by targeting on Robo1 in mice aortic endothelial cells under intermittent hypoxia

Retraction: Inhibition of microRNA-218 reduces HIF-1α by targeting on Robo1 in mice aortic endothelial cells under intermittent hypoxia

https://doi.org/10.18632/oncotarget.28449

Kai-Xiong Liu, Qin Chen, Gong-Ping Chen, Jian-Chai Huang, Jie-Feng Huang, Xin-Ru He, Ting Lin,  and Qi-Chang Lin
516-516
Retraction  |  PDF  |  How to cite

Research Papers

Value of chemotherapy post immunotherapy in stage IV non-small cell lung cancer (NSCLC)

Value of chemotherapy post immunotherapy in stage IV non-small cell lung cancer (NSCLC)

https://doi.org/10.18632/oncotarget.28444

Hazem I. Assi, Maroun Bou Zerdan, Mohammad Hodroj, Makram Khoury, Nour Sabiha Naji, Ghid Amhaz, Reine Abou Zeidane,  and Fadi El Karak
517-525
Abstract  |  PDF  |  Full Text  |  How to cite

Editorial

Combined targeting of HEDGEHOG signaling and BRD4 as a novel therapeutic option against melanoma

Combined targeting of HEDGEHOG signaling and BRD4 as a novel therapeutic option against melanoma

https://doi.org/10.18632/oncotarget.28441

Silvia Pietrobono,  and Barbara Stecca
526-527
PDF  |  How to cite

Research Papers

Association of mutation and expression of the brother of the regulator of imprinted sites (BORIS) gene with breast cancer progression

Association of mutation and expression of the brother of the regulator of imprinted sites (BORIS) gene with breast cancer progression

https://doi.org/10.18632/oncotarget.28442

Mohammad Salman Akhtar, Naseem Akhter, Arshi Talat, Raed A. Alharbi, Abdulmajeed A.A. Sindi, Faisal Klufah, Hanan E. Alyahyawi, Abdulmohsen Alruwetei, Abrar Ahmad, Mazin A. Zamzami, SVS Deo, Syed Akhtar Husain, Osama A. Badi,  and Mohammad Jahir Khan
528-541
Abstract  |  PDF  |  Full Text  |  How to cite

Addendum

Addendum: Laser speckle flowgraphy in juxtapapillary retinal capillary hemangioblastoma: a case report on natural course and therapeutic effect

Addendum: Laser speckle flowgraphy in juxtapapillary retinal capillary hemangioblastoma: a case report on natural course and therapeutic effect

https://doi.org/10.18632/oncotarget.28297

Mizuho Mitamura, Satoru Kase, Kiriko Hirooka,  and Susumu Ishida
542-542
Addendum  |  PDF  |  How to cite

Research Papers

Deconstructing the role of MALAT1 in MAPK-signaling in melanoma: insights from antisense oligonucleotide treatment

Deconstructing the role of MALAT1 in MAPK-signaling in melanoma: insights from antisense oligonucleotide treatment

https://doi.org/10.18632/oncotarget.28447

Valentin Feichtenschlager, Yixuan James Zheng, Wilson Ho, Linan Chen, Ciara Callanan, Christopher Chen, Albert Lee, Jose Ortiz, Klemens Rappersberger,  and Susana Ortiz-Urda
543-560
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release


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