Vol 7, No 12

A multimodal assessment of balance in elderly and young adults

Aging is a weak but relentless determinant of dementia severity

Effect of HMGCR genetic variation on neuroimaging biomarkers in healthy, mild cognitive impairment and Alzheimer’s disease cohorts

Escitalopram attenuates β-amyloid-induced tau hyperphosphorylation in primary hippocampal neurons through the 5-HT_1A receptor mediated Akt/GSK-3β pathway

Age-related changes in the transcriptome of antibody-secreting cells

Increased amyloid β-peptide uptake in skeletal muscle is induced by hyposialylation and may account for apoptosis in GNE myopathy

High circulating activin A level is associated with tumor progression and predicts poor prognosis in lung adenocarcinoma

Comparative analysis of human and mouse transcriptomes of Th17 cell priming

Targeting hypoxic response for cancer therapy

Competing endogenous RNA networks in human cancer: hypothesis, validation, and perspectives

A double feedback loop mediated by microRNA-23a/27a/24-2 regulates M1 versus M2 macrophage polarization and thus regulates cancer progression

KIAA0101 is associated with human renal cell carcinoma proliferation and migration induced by erythropoietin

SIRT1 inhibition impairs non-homologous end joining DNA damage repair by increasing Ku70 acetylation in chronic myeloid leukemia cells

Low expression of CD200 predicts shorter time-to-treatment in chronic lymphocytic leukemia

Disruption of CCL20-CCR6 interaction inhibits metastasis of advanced cutaneous T-cell lymphoma

FGF19 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells by modulating the GSK3β/β- catenin signaling cascade via FGFR4 activation

Association and prognostic significance of BRCA1/2-mutation status with neoantigen load, number of tumor-infiltrating lymphocytes and expression of PD-1/PD-L1 in high grade serous ovarian cancer

ERβ decreases the invasiveness of triple-negative breast cancer cells by regulating mutant p53 oncogenic function

Establishment of an integrated model incorporating standardised uptake value and N-classification for predicting metastasis in nasopharyngeal carcinoma

Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer

Upregulated TRIM29 promotes proliferation and metastasis of nasopharyngeal carcinoma via PTEN/AKT/mTOR signal pathway

Hyperinsulinemia enhances interleukin-17-induced inflammation to promote prostate cancer development in obese mice through inhibiting glycogen synthase kinase 3-mediated phosphorylation and degradation of interleukin-17 receptor

Metastatic pathway-specific transcriptome analysis identifies MFSD4 as a putative tumor suppressor and biomarker for hepatic metastasis in patients with gastric cancer

Comparison of the RECIST 1.0 and RECIST 1.1 in patients treated with targeted agents: a pooled analysis and review

CRP2, a new invadopodia actin bundling factor critically promotes breast cancer cell invasion and metastasis

MRTF/SRF dependent transcriptional regulation of TAZ in breast cancer cells

Single nucleotide polymorphism in the microRNA-199a binding site of HIF1A gene is associated with pancreatic ductal adenocarcinoma risk and worse clinical outcomes

Global proteomic profiling in multistep hepatocarcinogenesis and identification of PARP1 as a novel molecular marker in hepatocellular carcinoma

BAP1 suppresses lung cancer progression and is inhibited by miR-31

Predictive value of GGN and CAG repeat polymorphisms of androgen receptors in testicular cancer: a meta-analysis

Prognostic and predictive value of tumor-infiltrating lymphocytes for clinical therapeutic research in patients with non-small cell lung cancer

Antibody h-R3-dendrimer mediated siRNA has excellent endosomal escape and tumor targeted delivery ability, and represents efficient siPLK1 silencing and inhibition of cell proliferation, migration and invasion

Integrated genomic approaches identify upregulation of SCRN1 as a novel mechanism associated with acquired resistance to erlotinib in PC9 cells harboring oncogenic EGFR mutation

Long noncoding RNA Saf and splicing factor 45 increase soluble Fas and resistance to apoptosis

Nuclear localization of TEF3-1 promotes cell cycle progression and angiogenesis in cancer

Monoamine oxidase A (MAO A) inhibitors decrease glioma progression

Withaferin-A suppress AKT induced tumor growth in colorectal cancer cells

GADD45α and γ interaction with CDK11p58 regulates SPDEF protein stability and SPDEF-mediated effects on cancer cell migration

A propensity score matching analysis of survival following segmentectomy or wedge resection in early-stage lung invasive adenocarcinoma or squamous cell carcinoma

Prognostic and therapeutic role of targetable lesions in B-lineage acute lymphoblastic leukemia without recurrent fusion genes

Induction of methionine adenosyltransferase 2A in tamoxifen-resistant breast cancer cells

Acquisition of tumorigenic potential and enhancement of angiogenesis in pulmonary stem/progenitor cells through Oct-4 hyperexpression

Osteoactivin (GPNMB) ectodomain protein promotes growth and invasive behavior of human lung cancer cells

Novel potential serological prostate cancer biomarkers using CT100+ cancer antigen microarray platform in a multi-cultural South African cohort

Inhibition of the p53/hDM2 protein-protein interaction by cyclometallated iridium(III) compounds

Elevated expression of IFN-inducible CXCR3 ligands predicts poor prognosis in patients with non-metastatic clear-cell renal cell carcinoma

Analogs of the novel phytohormone, strigolactone, trigger apoptosis and synergize with PARP inhibitors by inducing DNA damage and inhibiting DNA repair

Enhanced eryptosis contributes to anemia in lung cancer patients

Targeting endothelial connexin40 inhibits tumor growth by reducing angiogenesis and improving vessel perfusion

Involvement of calprotectin (S100A8/A9) in molecular pathways associated with HNSCC

Crosstalk between RON and androgen receptor signaling in the development of castration resistant prostate cancer

Carcinoma-associated fucosylated antigens are markers of the epithelial state and can contribute to cell adhesion through CLEC17A (Prolectin)

Combining FoxP3 and Helios with GARP/LAP markers can identify expanded Treg subsets in cancer patients

Distinct features between MLH1-methylated and unmethylated colorectal carcinomas with the CpG island methylator phenotype: implications in the serrated neoplasia pathway

Expression of GADS enhances FLT3-induced mitogenic signaling

The mannose receptor LY75 (DEC205/CD205) modulates cellular phenotype and metastatic potential of ovarian cancer cells

Combination photoimmunotherapy with monoclonal antibodies recognizing different epitopes of human epidermal growth factor receptor 2: an assessment of phototherapeutic effect based on fluorescence molecular imaging

Expression of androgen receptor in non-muscle-invasive bladder cancer predicts the preventive effect of androgen deprivation therapy on tumor recurrence

Quantitative proteomics reveals the novel co-expression signatures in early brain development for prognosis of glioblastoma multiforme

Clinical implications of TP53 mutations in myelodysplastic syndromes treated with hypomethylating agents

DEPTOR suppresses the progression of esophageal squamous cell carcinoma and predicts poor prognosis

Synergic interaction between amyloid precursor protein and neural cell adhesion molecule promotes neurite outgrowth

Transcriptomic analysis of stage 1 versus advanced adult granulosa cell tumors

Longitudinal tracking of subpopulation dynamics and molecular changes during LNCaP cell castration and identification of inhibitors that could target the PSA−/lo castration-resistant cells

Parabolic relationship between sex-specific serum high sensitive C reactive protein and non-alcoholic fatty liver disease in chinese adults: a large population-based study

Myeloid neoplasms with isolated isochromosome 17q demonstrate a high frequency of mutations in SETBP1, SRSF2, ASXL1 and NRAS

BK K⁺ channel blockade inhibits radiation-induced migration/brain infiltration of glioblastoma cells

The molecular and clinical verification of therapeutic resistance via the p38 MAPK–Hsp27 axis in lung cancer

The significance of phosphorylated heat shock protein 27 on the prognosis of pancreatic cancer

RACK1 overexpression is linked to acquired imatinib resistance in gastrointestinal stromal tumor

Overexpression of TSC-22 (transforming growth factor- β-stimulated clone-22) causes marked obesity, splenic abnormality and B cell lymphoma in transgenic mice

Comparative effectiveness of light emitting diodes (LEDs) and Lasers in near infrared photoimmunotherapy

Zinc finger protein ZBTB20 is an independent prognostic marker and promotes tumor growth of human hepatocellular carcinoma by repressing FoxO1

Hedgehog inhibitors selectively target cell migration and adhesion of mantle cell lymphoma in bone marrow microenvironment

SIRT1 at the crossroads of AKT1 and ERβ in malignant pleural mesothelioma cells

The essential role of methylthioadenosine phosphorylase in prostate cancer

Retrospective study testing next generation sequencing of selected cancer-associated genes in resected prostate cancer

An alternatively spliced variant of CXCR3 mediates the metastasis of CD133+ liver cancer cells induced by CXCL9

Cross-platform comparison of independent datasets identifies an immune signature associated with improved survival in metastatic melanoma

HULC long noncoding RNA silencing suppresses angiogenesis by regulating ESM-1 via the PI3K/Akt/mTOR signaling pathway in human gliomas

Ubiquitin-specific protease 11 functions as a tumor suppressor by modulating Mgl-1 protein to regulate cancer cell growth

Inhibition of WIP1 phosphatase sensitizes breast cancer cells to genotoxic stress and to MDM2 antagonist nutlin-3

MeCP2 suppresses LIN28A expression via binding to its methylated-CpG islands in pancreatic cancer cells

Identification of a long non-coding RNA NR_026689 associated with lung carcinogenesis induced by NNK

Characterization of novel low passage primary and metastatic colorectal cancer cell lines

Role of erythropoietin in the angiogenic activity of bone marrow endothelial cells of MGUS and multiple myeloma patients

Reduction of gastric cancer proliferation and invasion by miR-15a mediated suppression of Bmi-1 translation

X-linked FHL1 as a novel therapeutic target for head and neck squamous cell carcinoma

Transcriptomic analysis of aggressive meningiomas identifies PTTG1 and LEPR as prognostic biomarkers independent of WHO grade

MicroRNA-410 acts as oncogene in NSCLC through downregulating SLC34A2 via activating Wnt/β-catenin pathway

MST3 promotes proliferation and tumorigenicity through the VAV2/Rac1 signal axis in breast cancer

Assessment of cholecystokinin 2 receptor (CCK2R) in neoplastic tissue

Bakuchiol suppresses proliferation of skin cancer cells by directly targeting Hck, Blk, and p38 MAP kinase

AB209630, a long non-coding RNA decreased expression in hypopharyngeal squamous cell carcinoma, influences proliferation, invasion, metastasis, and survival

Exosomes confer pro-survival signals to alter the phenotype of prostate cells in their surrounding environment

Nrf2 is the key to chemotherapy resistance in MCF7 breast cancer cells under hypoxia

MPC1, a key gene in cancer metabolism, is regulated by COUPTFII in human prostate cancer

Use of integrin alpha 6 transcripts in a stool mRNA assay for the detection of colorectal cancers at curable stages

Obatoclax impairs lysosomal function to block autophagy in cisplatin-sensitive and -resistant esophageal cancer cells

The cancer-testis antigens SPANX-A/C/D and CTAG2 promote breast cancer invasion

Therapeutic siRNA for drug-resistant HER2-positive breast cancer

A20 inhibits the motility of HCC cells induced by TNF-α

A predictive nomogram improved diagnostic accuracy and interobserver agreement of perirectal lymph nodes metastases in rectal cancer

The lectin-like oxidized LDL receptor-1: a new potential molecular target in colorectal cancer

Tumoral indoleamine 2, 3-dioxygenase 1 is regulated by monocytes and T lymphocytes collaboration in hepatocellular carcinoma

A novel miR-34a target, protein kinase D1, stimulates cancer stemness and drug resistance through GSK3/β-catenin signaling in breast cancer

The CDK4/6 inhibitor LY2835219 has potent activity in combination with mTOR inhibitor in head and neck squamous cell carcinoma

Distinct lncRNA transcriptional fingerprints characterize progressive stages of multiple myeloma

CIP2A down regulation enhances the sensitivity of pancreatic cancer cells to gemcitabine

Development of a novel HAC-based “gain of signal” quantitative assay for measuring chromosome instability (CIN) in cancer cells

Integrated quantitative proteomic and transcriptomic analysis of lung tumor and control tissue: a lung cancer showcase

Tumor necrosis factor-α and interferon-γ stimulate MUC16 (CA125) expression in breast, endometrial and ovarian cancers through NFκB

Glucose-regulated protein 94 deficiency induces squamous cell metaplasia and suppresses PTEN-null driven endometrial epithelial tumor development

APG101 efficiently rescues erythropoiesis in lower risk myelodysplastic syndromes with severe impairment of hematopoiesis

MicroRNA-323-3p inhibits cell invasion and metastasis in pancreatic ductal adenocarcinoma via direct suppression of SMAD2 and SMAD3

Telomere targeting with a novel G-quadruplex-interactive ligand BRACO-19 induces T-loop disassembly and telomerase displacement in human glioblastoma cells

Salmonella VNP20009-mediated RNA interference of ABCB5 moderated chemoresistance of melanoma stem cell and suppressed tumor growth more potently

The BMP inhibitor DAND5 in serum predicts poor survival in breast cancer

Primary tumor inflammation in gross tumor volume as a prognostic factor for nasopharyngeal carcinoma patients

Prognostic value of wait time in nasopharyngeal carcinoma treated with intensity modulated radiotherapy: a propensity matched analysis

Immunogenomics reveal molecular circuits of diclofenac induced liver injury in mice

Cilengitide in newly diagnosed glioblastoma: biomarker expression and outcome

The prevalence and clinicopathological features of programmed death-ligand 1 (PD-L1) expression: a pooled analysis of literatures

Fatty acid amide hydrolase inhibitors confer anti-invasive and antimetastatic effects on lung cancer cells

Gene expression analyses of primary melanomas reveal CTHRC1 as an important player in melanoma progression

Therapeutic evaluation of microRNA-15a and microRNA-16 in ovarian cancer

Effect of alpha-lipoic acid on radiation-induced small intestine injury in mice

FGFR1 promotes the stem cell-like phenotype of FGFR1-amplified non-small cell lung cancer cells through the Hedgehog pathway

P300 acetyltransferase regulates fatty acid synthase expression, lipid metabolism and prostate cancer growth

An increase in galectin-3 causes cellular unresponsiveness to IFN-γ-induced signal transduction and growth inhibition in gastric cancer cells

UBE2T promotes nasopharyngeal carcinoma cell proliferation, invasion, and metastasis by activating the AKT/GSK3β/β-catenin pathway

MiR-26a and miR-144 inhibit proliferation and metastasis of esophageal squamous cell cancer by inhibiting cyclooxygenase-2

Down-regulation of osteoprotegerin expression as a novel biomarker for colorectal carcinoma

Hypotaurine evokes a malignant phenotype in glioma through aberrant hypoxic signaling

Improved therapy for neuroblastoma using a combination approach: superior efficacy with vismodegib and topotecan

Early onset of hypertension and serum electrolyte changes as potential predictive factors of activity in advanced HCC patients treated with sorafenib: results from a retrospective analysis of the HCC-AVR group

A new staging system for nasopharyngeal carcinoma based on intensity-modulated radiation therapy: results of a prospective multicentric clinical study

The effect of neuraxial anesthesia on cancer recurrence and survival after cancer surgery: an updated meta-analysis

The expression of plakoglobin is a potential prognostic biomarker for patients with surgically resected lung adenocarcinoma