Vol 7, No 40

T-cell epitope strength in WAP-T mouse mammary carcinomas is an important determinant in PD1/PD-L1 immune checkpoint blockade therapy

p27^kip1 expression limits H-Ras-driven transformation and tumorigenesis by both canonical and non-canonical mechanisms

Piwil2 is reactivated by HPV oncoproteins and initiates cell reprogramming via epigenetic regulation during cervical cancer tumorigenesis

Interferon-gamma deficiency protects against aging-related goblet cell loss

Laminin modification subretinal bio-scaffold remodels retinal pigment epithelium-driven microenvironment in vitro and in vivo

FGF23 promotes myocardial fibrosis in mice through activation of β-catenin

Stromal p16 expression is significantly increased in malignant ovarian neoplasms

Evidence of cellular stress and caspase-3 resulting from a combined two-frequency signal in the cerebrum and cerebellum of Sprague-Dawley rats

Renal tubular epithelium-targeted peroxisome proliferator-activated receptor-γ maintains the epithelial phenotype and antagonizes renal fibrogenesis

Prognostic value of the Hippo pathway transcriptional coactivators YAP/TAZ and β1-integrin in conventional osteosarcoma

Mediation of episodic memory performance by the executive function network in patients with amnestic mild cognitive impairment: a resting-state functional MRI study

Expression of non-secreted IL-4 is associated with HDAC inhibitor-induced cell death, histone acetylation and c-Jun regulation in human gamma/delta T-cells

Identification and validation of COX-2 as a co-target for overcoming cetuximab resistance in colorectal cancer cells

CD147 silencing inhibits tumor growth by suppressing glucose transport in melanoma

CD45 phosphatase is crucial for human and murine acute myeloid leukemia maintenance through its localization in lipid rafts

Predictive and prognostic value of preoperative serum tumor markers in resectable adenosqamous lung carcinoma

p16/Ki-67 co-expression associates high risk human papillomavirus persistence and cervical histopathology: a 3-year cohort study in China

HuR silencing elicits oxidative stress and DNA damage and sensitizes human triple-negative breast cancer cells to radiotherapy

Ovarian hormones through Wnt signalling regulate the growth of human and mouse ovarian cancer initiating lesions

Bone marrow adipocytes promote the Warburg phenotype in metastatic prostate tumors via HIF-1α activation

Carcinogen 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis is accelerated in Smad3 heterozygous mice compared to Smad3 wild type mice

An oncogenic role for sphingosine kinase 2

High expression of microRNA-454 is associated with poor prognosis in triple-negative breast cancer

Immunohistochemical correlates of TP53 somatic mutations in cancer

The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer

miR-29 regulates Tet1 expression and contributes to early differentiation of mouse ESCs

Synthetic ligands of death receptor 5 display a cell-selective agonistic effect at different oligomerization levels

Neuraminidase 1 (NEU1) promotes proliferation and migration as a diagnostic and prognostic biomarker of hepatocellular carcinoma

Discovery of peptide inhibitors targeting human programmed death 1 (PD-1) receptor

Proto-oncogenic miR-744 is upregulated by transcription factor c-Jun via a promoter activation mechanism

Targeting prohibitins induces apoptosis in acute myeloid leukemia cells

Drp1-mediated mitochondrial fission promotes cell proliferation through crosstalk of p53 and NF-κB pathways in hepatocellular carcinoma

Antineoplastic effects and mechanisms of micheliolide in acute myelogenous leukemia stem cells

Luminal B breast cancer: patterns of recurrence and clinical outcome

Influence of wound fluid on chemotherapy sensitivity in primary breast cancer cells

Radiofrequency hyperthermia promotes the therapeutic effects on chemotherapeutic-resistant breast cancer when combined with heat shock protein promoter-controlled HSV-TK gene therapy: Toward imaging-guided interventional gene therapy

Elevated CXCL1 increases hepatocellular carcinoma aggressiveness and is inhibited by miRNA-200a

Dysregulation of the BRCA1/long non-coding RNA NEAT1 signaling axis contributes to breast tumorigenesis

Dux4 controls migration of mesenchymal stem cells through the Cxcr4-Sdf1 axis

Ligand-activated PPARγ downregulates CXCR4 gene expression through a novel identified PPAR response element and inhibits breast cancer progression

Tumor treating fields inhibit glioblastoma cell migration, invasion and angiogenesis

The ELK3-GATA3 axis orchestrates invasion and metastasis of breast cancer cells in vitro and in vivo

RALB provides critical survival signals downstream of Ras in acute myeloid leukemia

Co-inhibition of pol θ and HR genes efficiently synergize with cisplatin to suppress cisplatin-resistant lung cancer cells survival

A Pyrazolo[3,4-d]pyrimidine compound inhibits Fyn phosphorylation and induces apoptosis in natural killer cell leukemia

Clinical outcomes of advanced non-small-cell lung cancer patients with EGFR mutation, ALK rearrangement and EGFR/ALK co-alterations

Association of nonsteroidal anti-inflammatory drugs and aspirin use and the risk of head and neck cancers: a meta-analysis of observational studies

Noninvasive genotyping and monitoring of anaplastic lymphoma kinase (ALK) rearranged non-small cell lung cancer by capture-based next-generation sequencing

SIRT1-mediated FoxOs pathways protect against apoptosis by promoting autophagy in osteoblast-like MC3T3-E1 cells exposed to sodium fluoride

O-mannosylation and N-glycosylation: two coordinated mechanisms regulating the tumour suppressor functions of E-cadherin in cancer

The elevated preoperative fasting blood glucose predicts a poor prognosis in patients with esophageal squamous cell carcinoma: The Fujian prospective investigation of cancer (FIESTA) study

HGIMDA: Heterogeneous graph inference for miRNA-disease association prediction

Statins dose-dependently exert a significant chemopreventive effect on colon cancer in patients with chronic obstructive pulmonary disease: A population-based cohort study

GATA3 expression correlates with poor prognosis and tumor-associated macrophage infiltration in peripheral T cell lymphoma

The mitochondrial and endoplasmic reticulum pathways involved in the apoptosis of bursa of Fabricius cells in broilers exposed to dietary aflatoxin B₁

MIEN1 is tightly regulated by SINE Alu methylation in its promoter

Nucleolin-binding by ErbB2 enhances tumorigenicity of ErbB2-positive breast cancer

Endoplasmic reticulum-Golgi intermediate compartment protein 3 knockdown suppresses lung cancer through endoplasmic reticulum stress-induced autophagy

Cell-permeable iron inhibits vascular endothelial growth factor receptor-2 signaling and tumor angiogenesis

Concordance between genomic alterations assessed by next-generation sequencing in tumor tissue or circulating cell-free DNA

ST6Gal-I overexpression facilitates prostate cancer progression via the PI3K/Akt/GSK-3β/β-catenin signaling pathway

Activation of AKT pathway by Nrf2/PDGFA feedback loop contributes to HCC progression

Foxp3 enhances HIF-1α target gene expression in human bladder cancer through decreasing its ubiquitin-proteasomal degradation

Cross-linked hyaluronic acid gel inhibits metastasis and growth of gastric and hepatic cancer cells: in vitro and in vivo studies

Tumor vessel normalization after aerobic exercise enhances chemotherapeutic efficacy

Leptin promotes migration and invasion of breast cancer cells by stimulating IL-8 production in M2 macrophages

Hypoxia-responsive miR-210 promotes self-renewal capacity of colon tumor-initiating cells by repressing ISCU and by inducing lactate production

TGFβ upregulates PAR-1 expression and signalling responses in A549 lung adenocarcinoma cells

Genomic characterization of pediatric T-cell acute lymphoblastic leukemia reveals novel recurrent driver mutations

Targeting DNA double strand break repair with hyperthermia and DNA-PKcs inhibition to enhance the effect of radiation treatment

c-Myc targeted regulators of cell metabolism in a transgenic mouse model of papillary lung adenocarcinoma

STA-8666, a novel HSP90 inhibitor/SN-38 drug conjugate, causes complete tumor regression in preclinical mouse models of pediatric sarcoma

Role of RbBP5 and H3K4me3 in the vicinity of Snail transcription start site during epithelial-mesenchymal transition in prostate cancer cell

The prognostic value of D-dimer levels in metastatic osteosarcoma patients treated with second-line chemotherapy

The use of and adherence to CTCAE v3.0 in cancer clinical trial publications

Paradoxical overexpression of MBNL2 in hepatocellular carcinoma inhibits tumor growth and invasion

Role of EGF/ERBB1 in the transcriptional regulation of the prolactin receptor independent of estrogen and prolactin in breast cancer cells

Glutathione may have implications in the design of 3-bromopyruvate treatment protocols for both fungal and algal infections as well as multiple myeloma

Evaluation of in vitro effects of various targeted drugs on plasma cells and putative neoplastic stem cells in patients with multiple myeloma

Inhibiting stemness and invasive properties of glioblastoma tumorsphere by combined treatment with temozolomide and a newly designed biguanide (HL156A)

Activation of autophagic flux by epigallocatechin gallate mitigates TRAIL-induced tumor cell apoptosis via down-regulation of death receptors

Dietary energy restriction reduces high-fat diet-enhanced metastasis of Lewis lung carcinoma in mice

SHP-2 phosphatase contributes to KRAS-driven intestinal oncogenesis but prevents colitis-associated cancer development

Characterizing and targeting PDGFRA alterations in pediatric high-grade glioma

Eupafolin enhances TRAIL-mediated apoptosis through cathepsin S-induced down-regulation of Mcl-1 expression and AMPK-mediated Bim up-regulation in renal carcinoma Caki cells

Superior anti-tumor efficacy of diisopropylamine dichloroacetate compared with dichloroacetate in a subcutaneous transplantation breast tumor model

Glycycoumarin exerts anti-liver cancer activity by directly targeting T-LAK cell-originated protein kinase

Decreased miR-320a promotes invasion and metastasis of tumor budding cells in tongue squamous cell carcinoma

Novel association of DJ-1 with HER3 potentiates HER3 activation and signaling in cancer

Predictive value of XPG rs2296147T>C polymorphism on clinical outcomes of cancer patients

Involvement of let-7 microRNA for the therapeutic effects of Rhenium-188-embedded liposomal nanoparticles on orthotopic human head and neck cancer model

Stat3 accelerates Myc induced tumor formation while reducing growth rate in a mouse model of breast cancer

The small heat shock protein αA-crystallin negatively regulates pancreatic tumorigenesis

Interleukin-32α induces migration of human melanoma cells through downregulation of E-cadherin

LY6E: a conductor of malignant tumor growth through modulation of the PTEN/PI3K/Akt/HIF-1 axis

Oxysterol-binding protein-related protein 4L promotes cell proliferation by sustaining intracellular Ca²⁺ homeostasis in cervical carcinoma cell lines

Cancer stem cell markers predict a poor prognosis in renal cell carcinoma: a meta-analysis

UBE2C is overexpressed in ESCC tissues and its abrogation attenuates the malignant phenotype of ESCC cell lines

Cancer stem cells from human glioblastoma resemble but do not mimic original tumors after in vitro passaging in serum-free media

T cell abundance in blood predicts acute organ toxicity in chemoradiotherapy for head and neck cancer

Genetic variants of SOX9 contribute to susceptibility of gliomas among Chinese population

Direct interaction of Ikaros and Foxp1 modulates expression of the G protein-coupled receptor G2A in B-lymphocytes and acute lymphoblastic leukemia

Metastatic lymph node ratio can further stratify risk for mortality in medullary thyroid cancer patients: A population-based analysis

c-Fos over-expression promotes radioresistance and predicts poor prognosis in malignant glioma

Inhibition of never in mitosis A (NIMA)-related kinase-4 reduces survivin expression and sensitizes cancer cells to TRAIL-induced cell death

Ibrutinib modifies the function of monocyte/macrophage population in chronic lymphocytic leukemia

Pancreatic stellate cell secreted IL-6 stimulates STAT3 dependent invasiveness of pancreatic intraepithelial neoplasia and cancer cells

Analysis of the hormone receptor status of circulating tumor cell subpopulations based on epithelial-mesenchymal transition: a proof-of-principle study on the heterogeneity of circulating tumor cells

Identification of candidate anti-cancer molecular mechanisms of Compound Kushen Injection using functional genomics

ctDNA dynamics: a novel indicator to track resistance in metastatic breast cancer treated with anti-HER2 therapy

Rig-G is a growth inhibitory factor of lung cancer cells that suppresses STAT3 and NF-κB

MiR-155 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells through the activation of PI3K/SGK3/β-catenin signaling pathways

The association analysis of hOGG1 genetic variants and gastric cancer risk in a Chinese population

Single-cell analyses of transcriptional heterogeneity in squamous cell carcinoma of urinary bladder

Epithelialization of mouse ovarian tumor cells originating in the fallopian tube stroma

Circadian clock components RORα and Bmal1 mediate the anti-proliferative effect of MLN4924 in osteosarcoma cells

SP110 and PMP22 polymorphisms are associated with tuberculosis risk in a Chinese-Tibetan population

Association between cyclin D1 (CCND1) G870A polymorphism and gastric cancer risk: a meta-analysis

Sialylation transmogrifies human breast and pancreatic cancer cells into 3D multicellular tumor spheroids using cyclic RGD-peptide induced self-assembly

Neuropeptide Y-mediated sex- and afferent-specific neurotransmissions contribute to sexual dimorphism of baroreflex afferent function

Adjuvant treatment may benefit patients with high-risk upper rectal cancer: a nomogram and recursive partitioning analysis of 547 patients

Old age at diagnosis increases risk of tumor progression in nasopharyngeal cancer

Incidence and relative risk of hemorrhagic events associated with ramucirumab in cancer patients: a systematic review and meta-analysis

Primary analysis of a prospective, randomized, single-blinded phase II trial evaluating the HER2 peptide GP2 vaccine in breast cancer patients to prevent recurrence

Patient-derived xenograft models of colorectal cancer in pre-clinical research: a systematic review

The etiologic spectrum of head and neck squamous cell carcinoma in young patients

Adenoid cystic carcinoma: emerging role of translocations and gene fusions

Targeting binding partners of the CBFβ-SMMHC fusion protein for the treatment of inversion 16 acute myeloid leukemia

PinX1: structure, regulation and its functions in cancer

p53, a potential predictor of Helicobacter pylori infection-associated gastric carcinogenesis?

The BCR-ABL/NF-κB signal transduction network: a long lasting relationship in Philadelphia positive Leukemias

Mast cell sarcoma: new cases and literature review

IκBζ: an emerging player in cancer