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The cover for issue 35 of Oncotarget features Figure 6 (Effects of BMP9 and VEGFR2 blockade on CNV) from Ntumba, et al.
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Table of Contents
Priority Research Papers
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| Immortalization of human AE preleukemia cells by hTERT allows leukemic transformation |
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https://doi.org/10.18632/oncotarget.11093
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| 55939-55950 |
Research Papers: Gerotarget (Focus on Aging)
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| GDF11 administration does not extend lifespan in a mouse model of premature aging |
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https://doi.org/10.18632/oncotarget.11096
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| 55951-55956 |
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| BMP9/ALK1 inhibits neovascularization in mouse models of agerelated macular degeneration |
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https://doi.org/10.18632/oncotarget.11182
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| 55957-55969 |
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| Biological relevance of fatty acyl heterogeneity to the neural membrane dynamics of Rhesus macaques during normative aging |
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https://doi.org/10.18632/oncotarget.11190
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| 55970-55989 |
Research Papers: Pathology
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| α2adrenoreceptor modulated FAK pathway induced by dexmedetomidine attenuates pulmonary microvascular hyperpermeability following kidney injury |
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https://doi.org/10.18632/oncotarget.10809
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| 55990-56001 |
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| Porcine reproductive and respiratory syndrome virus triggers mitochondrial fission and mitophagy to attenuate apoptosis |
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https://doi.org/10.18632/oncotarget.10817
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| 56002-56012 |
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| Multiple myelomaderived Jagged ligands increases autocrine and paracrine interleukin6 expression in bone marrow niche |
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https://doi.org/10.18632/oncotarget.10820
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| 56013-56029 |
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| Potential implications of Apolipoprotein E in early brain injury after experimental subarachnoid hemorrhage: Involvement in the modulation of bloodbrain barrier integrity |
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https://doi.org/10.18632/oncotarget.10821
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| 56030-56044 |
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| Resveratrol counteracts lipopolysaccharideinduced depressivelike behaviors via enhanced hippocampal neurogenesis |
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https://doi.org/10.18632/oncotarget.11178
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| 56045-56059 |
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| Overexpression of complement component C5a accelerates the development of atherosclerosis in ApoEknockout mice |
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https://doi.org/10.18632/oncotarget.11180
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| 56060-56070 |
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| Butyrate alleviates high fat dietinduced obesity through activation of adiponectinmediated pathway and stimulation of mitochondrial function in the skeletal muscle of mice |
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https://doi.org/10.18632/oncotarget.11267
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| 56071-56082 |
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| The HERC2 ubiquitin ligase is essential for embryonic development and regulates motor coordination |
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https://doi.org/10.18632/oncotarget.11270
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| 56083-56106 |
Research Papers: Immunology
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| HBV suppresses expression of MICA/B on hepatoma cells through upregulation of transcription factors GATA2 and GATA3 to escape from NK cell surveillance |
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https://doi.org/10.18632/oncotarget.11271
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| 56107-56119 |
Research Papers: Neuroscience
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| Analysis of the influence of memory content of auditory stimuli on the memory content of EEG signal |
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https://doi.org/10.18632/oncotarget.11234
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| 56120-56128 |
Research Papers
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| Besides an ITIM/SHP1dependent pathway CD22 collaborates with Grb2 and plasma membrane calciumATPase in an ITIM/SHP1independent pathway of attenuation of Ca2+i signal in B cells |
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https://doi.org/10.18632/oncotarget.9794
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| 56129-56146 |
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| OASIS 2: online application for survival analysis 2 with features for the analysis of maximal lifespan and healthspan in aging research |
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https://doi.org/10.18632/oncotarget.11269
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| 56147-56152 |
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| Mechanism of BRG1 silencing in primary cancers |
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https://doi.org/10.18632/oncotarget.10593
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| 56153-56169 |
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| Memo interacts with cSrc to control Estrogen Receptor alpha subcellular localization |
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https://doi.org/10.18632/oncotarget.10856
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| 56170-56182 |
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| Targeting Zfp148 activates p53 and reduces tumor initiation in the gut |
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https://doi.org/10.18632/oncotarget.10899
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| 56183-56192 |
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| Overexpressed LAPTM4B35 is a risk factor for cancer recurrence and poor prognosis in nonsmallcell lung cancer |
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https://doi.org/10.18632/oncotarget.10907
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| 56193-56199 |
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| MicroRNA564 is downregulated in glioblastoma and inhibited proliferation and invasion of glioblastoma cells by targeting TGFβ1 |
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https://doi.org/10.18632/oncotarget.8987
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| 56200-56208 |
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| The lncRNA MALAT1 is a novel biomarker for gastric cancer metastasis |
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https://doi.org/10.18632/oncotarget.10941
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| 56209-56218 |
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| Novel antiCD3 chimeric antigen receptor targeting of aggressive T cell malignancies |
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https://doi.org/10.18632/oncotarget.11019
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| 56219-56232 |
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| Expression of PD1 on CD4+ T cells in peripheral blood associates with poor clinical outcome in nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.9316
|
| 56233-56240 |
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| The photosensitizer verteporfin has lightindependent antileukemic activity for Phpositive acute lymphoblastic leukemia and synergistically works with dasatinib |
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https://doi.org/10.18632/oncotarget.11025
|
| 56241-56252 |
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| Smac mimetic LCL161 overcomes protective ER stress induced by obatoclax synergistically causing cell death in multiple myeloma |
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https://doi.org/10.18632/oncotarget.11028
|
| 56253-56265 |
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| Loss of MYC and Ebox3 binding contributes to defective MYCmediated transcriptional suppression of human MClet7a1~let7d in glioblastoma |
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https://doi.org/10.18632/oncotarget.10517
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| 56266-56278 |
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| Procoagulant and immunogenic properties of melanoma exosomes microvesicles and apoptotic vesicles |
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https://doi.org/10.18632/oncotarget.10783
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| 56279-56294 |
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| Gasdermin B expression predicts poor clinical outcome in HER2positive breast cancer |
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https://doi.org/10.18632/oncotarget.10787
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| 56295-56308 |
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| Nuclear IKKα mediates microRNA7/103/107/21 inductions to downregulate maspin expression in response to HBx overexpression |
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https://doi.org/10.18632/oncotarget.10462
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| 56309-56323 |
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| Microenvironment mediated alterations to metabolic pathways confer increased chemoresistance in CD133+ tumor initiating cells |
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https://doi.org/10.18632/oncotarget.10838
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| 56324-56337 |
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| EZH2mediated Puma gene repression regulates nonsmall cell lung cancer cell proliferation and cisplatininduced apoptosis |
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https://doi.org/10.18632/oncotarget.10841
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| 56338-56354 |
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| TAM receptors Tyro3 and Mer as novel targets in colorectal cancer |
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https://doi.org/10.18632/oncotarget.10889
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| 56355-56370 |
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| Combining GRP78 suppression and MK2206induced Akt inhibition decreases doxorubicininduced Pglycoprotein expression and mitigates chemoresistance in human osteosarcoma |
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https://doi.org/10.18632/oncotarget.10890
|
| 56371-56382 |
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| Construction and analysis of dysregulated lncRNAassociated ceRNA network identified novel lncRNA biomarkers for early diagnosis of human pancreatic cancer |
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https://doi.org/10.18632/oncotarget.10891
|
| 56383-56394 |
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| Intratumoral heterogeneity of the therapeutical response to gemcitabine and metformin |
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https://doi.org/10.18632/oncotarget.10892
|
| 56395-56407 |
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| Inhibition of the colonystimulatingfactor1 receptor affects the resistance of lung cancer cells to cisplatin |
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https://doi.org/10.18632/oncotarget.10895
|
| 56408-56421 |
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| CMyc functions as a competing endogenous RNA in acute promyelocytic leukemia |
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https://doi.org/10.18632/oncotarget.10896
|
| 56422-56430 |
|
| DICER governs characteristics of glioma stem cells and the resulting tumors in xenograft mouse models of glioblastoma |
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https://doi.org/10.18632/oncotarget.10570
|
| 56431-56446 |
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| Significant impact of amount of PCR input templates on various PCRbased DNA methylation analysis and countermeasure |
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https://doi.org/10.18632/oncotarget.10906
|
| 56447-56455 |
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| Repurposing phenformin for the targeting of glioma stem cells and the treatment of glioblastoma |
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https://doi.org/10.18632/oncotarget.10919
|
| 56456-56470 |
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| [64Cu]XYIMSR06: A dualmotif CAIX ligand for PET imaging of clear cell renal cell carcinoma |
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https://doi.org/10.18632/oncotarget.10602
|
| 56471-56479 |
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| Identification of genetic variants predictive of early onset pancreatic cancer through a population science analysis of functional genomic datasets |
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https://doi.org/10.18632/oncotarget.10924
|
| 56480-56490 |
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| Clinical benefit of a precision medicine based approach for guiding treatment of refractory cancers |
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https://doi.org/10.18632/oncotarget.10606
|
| 56491-56500 |
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| Association of the GLB1 rs4678680 genetic variant with risk of HBVrelated hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.10963
|
| 56501-56507 |
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| The in vitro and vivo antitumor effects and molecular mechanisms of suberoylanilide hydroxamic acid SAHA and MG132 on the aggressive phenotypes of gastric cancer cells |
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https://doi.org/10.18632/oncotarget.10643
|
| 56508-56525 |
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| The prognostic value of CSCs biomarker CD133 in NSCLC: a metaanalysis |
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https://doi.org/10.18632/oncotarget.10964
|
| 56526-56539 |
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| XIAP RING domain mediates miR4295 expression and subsequently inhibiting p63α protein translation and promoting transformation of bladder epithelial cells |
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https://doi.org/10.18632/oncotarget.10645
|
| 56540-56557 |
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| Pregnane Xreceptor promotes stem cellmediated colon cancer relapse |
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https://doi.org/10.18632/oncotarget.10646
|
| 56558-56573 |
|
| Increased frequency of circulating Th22 cells in patients with Bcell nonHodgkin’s lymphoma |
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https://doi.org/10.18632/oncotarget.10966
|
| 56574-56583 |
|
| Lysosomeassociated membrane glycoprotein 1 predicts fratricide amongst T cell receptor transgenic CD8+ T cells directed against tumorassociated antigens |
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https://doi.org/10.18632/oncotarget.10647
|
| 56584-56597 |
|
| Notch1 directly induced CD133 expression in human diffuse type gastric cancers |
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https://doi.org/10.18632/oncotarget.10967
|
| 56598-56607 |
|
| Urbanrural disparity of overweight/obesity distribution and its potential trend with breast cancer among Chinese women |
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https://doi.org/10.18632/oncotarget.10968
|
| 56608-56618 |
|
| Fatal gastrointestinal toxicity with ipilimumab after BRAF/ MEK inhibitor combination in a melanoma patient achieving pathological complete response |
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https://doi.org/10.18632/oncotarget.10651
|
| 56619-56627 |
|
| miR199a3p targets stemnessrelated and mitogenic signaling pathways to suppress the expansion and tumorigenic capabilities of prostate cancer stem cells |
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https://doi.org/10.18632/oncotarget.10652
|
| 56628-56642 |
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| Decreased fucosylated PSA as a urinary marker for high Gleason score prostate cancer |
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https://doi.org/10.18632/oncotarget.10987
|
| 56643-56649 |
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| Guttiferone K suppresses cell motility and metastasis of hepatocellular carcinoma by restoring aberrantly reduced profilin 1 |
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https://doi.org/10.18632/oncotarget.10992
|
| 56650-56663 |
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| Met promotes the formation of double minute chromosomes induced by Sei1 in NIH3T3 murine fibroblasts |
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https://doi.org/10.18632/oncotarget.10994
|
| 56664-56675 |
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| Next generation multiscale biophysical characterization of high precision cancer particle radiotherapy using clinical proton helium carbon and oxygen ion beams |
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https://doi.org/10.18632/oncotarget.10996
|
| 56676-56689 |
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| Seven protective miRNA signatures for prognosis of cervical cancer |
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https://doi.org/10.18632/oncotarget.10678
|
| 56690-56698 |
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| Regulation of cellular quiescence by YAP/TAZ and Cyclin E1 in colon cancer cells: Implication in chemoresistance and cancer relapse |
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https://doi.org/10.18632/oncotarget.11057
|
| 56699-56712 |
|
| Slowing down glioblastoma progression in mice by running or the antimalarial drug dihydroartemisinin Induction of oxidative stress in murine glioblastoma therapy |
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https://doi.org/10.18632/oncotarget.10723
|
| 56713-56725 |
|
| Comparative proteomic profiling of refractory/relapsed multiple myeloma reveals biomarkers involved in resistance to bortezomibbased therapy |
|
https://doi.org/10.18632/oncotarget.11059
|
| 56726-56736 |
|
| Genetic variations in apoptosis pathway and the risk of ovarian cancer |
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https://doi.org/10.18632/oncotarget.10772
|
| 56737-56745 |
|
| Genomic complexity and dynamics of clonal evolution in childhood acute myeloid leukemia studied with wholeexome sequencing |
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https://doi.org/10.18632/oncotarget.10778
|
| 56746-56757 |
|
| An integrative framework to identify cell deathrelated microRNAs in esophageal squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.10779
|
| 56758-56766 |
|
| Delphinidin induces apoptosis via cleaved HDAC3mediated p53 acetylation and oligomerization in prostate cancer cells |
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https://doi.org/10.18632/oncotarget.10790
|
| 56767-56780 |
|
| Gene expression analysis of TIL rich HPVdriven head and neck tumors reveals a distinct Bcell signature when compared to HPV independent tumors |
|
https://doi.org/10.18632/oncotarget.10788
|
| 56781-56797 |
|
| Methylation of S100A8 is a promising diagnosis and prognostic marker in hepatocellular carcinoma |
|
https://doi.org/10.18632/oncotarget.10792
|
| 56798-56810 |
|
| Inhibition of Mnk enhances apoptotic activity of cytarabine in acute myeloid leukemia cells |
|
https://doi.org/10.18632/oncotarget.10796
|
| 56811-56825 |
|
| IGF1R inhibition sensitizes breast cancer cells to ATMrelated kinase ATR inhibitor and cisplatin |
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https://doi.org/10.18632/oncotarget.10862
|
| 56826-56841 |
|
| Targeting XBP1mediated βcatenin expression associated with bladder cancer with newly synthetic Oridonin analogues |
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https://doi.org/10.18632/oncotarget.10863
|
| 56842-56854 |
|
| Tumor exosomemediated promotion of adhesion to mesothelial cells in gastric cancer cells |
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https://doi.org/10.18632/oncotarget.10869
|
| 56855-56863 |
|
| Inhibition of cyclin dependent kinase 9 by dinaciclib suppresses cyclin B1 expression and tumor growth in triple negative breast cancer |
|
https://doi.org/10.18632/oncotarget.10870
|
| 56864-56875 |
|
| Fulvestrant inhibits growth of triple negative breast cancer and synergizes with tamoxifen in ERα positive breast cancer by upregulation of ERβ |
|
https://doi.org/10.18632/oncotarget.10871
|
| 56876-56888 |
|
| Caveolin1 promotes Ewing sarcoma metastasis regulating MMP9 expression through MAPK/ERK pathway |
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https://doi.org/10.18632/oncotarget.10872
|
| 56889-56903 |
|
| A threedimensional collagen scaffold cell culture system for screening antiglioma therapeutics |
|
https://doi.org/10.18632/oncotarget.10885
|
| 56904-56914 |
|
| Association between dietary nitrate and nitrite intake and sitespecific cancer risk: evidence from observational studies |
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https://doi.org/10.18632/oncotarget.10917
|
| 56915-56932 |
|
| Loss of ARID1A expression leads to sensitivity to ROSinducing agent elesclomol in gynecologic cancer cells |
|
https://doi.org/10.18632/oncotarget.10921
|
| 56933-56943 |
|
| IGFII induced by hepatitis B virus X protein regulates EMT via SUMO mediated loss of Ecadherin in mice |
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https://doi.org/10.18632/oncotarget.10922
|
| 56944-56957 |
|
| A role for activated Cdc42 in glioblastoma multiforme invasion |
|
https://doi.org/10.18632/oncotarget.10925
|
| 56958-56975 |
|
| Telomere status in chronic lymphocytic leukemia with TP53 disruption |
|
https://doi.org/10.18632/oncotarget.10927
|
| 56976-56985 |
|
| Functional intratumoral lymphatics in patientderived xenograft models of squamous cell carcinoma of the uterine cervix: implications for lymph node metastasis |
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https://doi.org/10.18632/oncotarget.10931
|
| 56986-56997 |
|
| A retrospective analysis in patients with EGFRmutant lung adenocarcinoma: is EGFR mutation associated with a higher incidence of brain metastasis |
|
https://doi.org/10.18632/oncotarget.10933
|
| 56998-57010 |
|
| Functional single nucleotide polymorphisms within the cyclindependent kinase inhibitor 2A/2B region affect pancreatic cancer risk |
|
https://doi.org/10.18632/oncotarget.10935
|
| 57011-57020 |
|
| Targeted deep sequencing improves outcome stratification in chronic myelomonocytic leukemia with low risk cytogenetic features |
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https://doi.org/10.18632/oncotarget.10937
|
| 57021-57035 |
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| Coexistence of JAK2 and CALR mutations and their clinical implications in patients with essential thrombocythemia |
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https://doi.org/10.18632/oncotarget.10958
|
| 57036-57049 |
|
| HPV16 E6E7 induces cancer stemlike cells phenotypes in esophageal squamous cell carcinoma through the activation of PI3K/Akt signaling pathway in vitro and in vivo |
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https://doi.org/10.18632/oncotarget.10959
|
| 57050-57065 |
|
| Twist1induced epithelialmesenchymal transition according to microsatellite instability status in colon cancer cells |
|
https://doi.org/10.18632/oncotarget.10974
|
| 57066-57076 |
|
| Differential expression of cyclooxygenase2 in metastatic melanoma affects progression free survival |
|
https://doi.org/10.18632/oncotarget.10976
|
| 57077-57085 |
|
| Expression of the p66Shc protein adaptor is regulated by the activator of transcription STAT4 in normal and chronic lymphocytic leukemia B cells |
|
https://doi.org/10.18632/oncotarget.10977
|
| 57086-57098 |
|
| MiRNA22 inhibits oncogene galectin1 in hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.10981
|
| 57099-57116 |
|
| Ablation of human telomerase reverse transcriptase hTERT induces cellular senescence in gastric cancer through a galectin3 dependent mechanism |
|
https://doi.org/10.18632/oncotarget.10986
|
| 57117-57130 |
|
| GSK3β inactivation promotes the oncogenic functions of EZH2 and enhances methylation of H3K27 in human breast cancers |
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https://doi.org/10.18632/oncotarget.11008
|
| 57131-57144 |
|
| Analysis of the chemotherapeutic effects of a propadiene compound on malignant ovarian cancer cells |
|
https://doi.org/10.18632/oncotarget.11012
|
| 57145-57159 |
|
| DR5 mAbconjugated DTICloaded immunonanoparticles effectively and specifically kill malignant melanoma cells in vivo |
|
https://doi.org/10.18632/oncotarget.11014
|
| 57160-57170 |
|
| Combinatorial therapeutic targeting of BMP2 and MEKERK pathways in NF1associated malignant peripheral nerve sheath tumors |
|
https://doi.org/10.18632/oncotarget.11036
|
| 57171-57185 |
|
| OGlcNAcylation of ATG4B positively regulates autophagy by increasing its hydroxylase activity |
|
https://doi.org/10.18632/oncotarget.11083
|
| 57186-57196 |
|
| The VEGF rise in blood of bevacizumab patients is not based on tumor escape but a hostblockade of VEGF clearance |
|
https://doi.org/10.18632/oncotarget.11084
|
| 57197-57212 |
|
| Celecoxib and sulindac inhibit TGFβ1induced epithelialmesenchymal transition and suppress lung cancer migration and invasion via downregulation of sirtuin 1 |
|
https://doi.org/10.18632/oncotarget.11127
|
| 57213-57227 |
|
| The gain and loss of long noncoding RNA associatedcompeting endogenous RNAs in prostate cancer |
|
https://doi.org/10.18632/oncotarget.11128
|
| 57228-57238 |
|
| Integrative analysis of miRNA and gene expression reveals regulatory networks in tamoxifenresistant breast cancer |
|
https://doi.org/10.18632/oncotarget.11136
|
| 57239-57253 |
|
| miR31 targets ARID1A and enhances the oncogenicity and stemness of head and neck squamous cell carcinoma |
|
https://doi.org/10.18632/oncotarget.11138
|
| 57254-57267 |
Clinical Research Papers
|
| Intravascular emboli is an independent risk factor for the prognosis of stage III colorectal cancer patients after radical surgery |
|
https://doi.org/10.18632/oncotarget.11266
|
| 57268-57276 |
|
| Optical imaging of gastric cancer with nearinfrared heptamethine carbocyanine fluorescence dyes |
|
https://doi.org/10.18632/oncotarget.10031
|
| 57277-57289 |
|
| Predictive value of chemotherapyrelated highdensity lipoprotein cholesterol HDL elevation in patients with colorectal cancer receiving adjuvant chemotherapy: an exploratory analysis of 851 cases |
|
https://doi.org/10.18632/oncotarget.10145
|
| 57290-57300 |
|
| Fulvestrant 500 mg vs 250 mg in postmenopausal women with estrogen receptorpositive advanced breast cancer: a randomized doubleblind registrational trial in China |
|
https://doi.org/10.18632/oncotarget.10254
|
| 57301-57309 |
|
| A phase II study of concurrent chemoradiotherapy and erlotinib for inoperable esophageal squamous cell carcinoma |
|
https://doi.org/10.18632/oncotarget.9809
|
| 57310-57316 |
|
| Preoperative chemoradiotherapy creates an opportunity to perform sphincter preserving resection for lowlying locally advanced rectal cancer based on an oncologic outcome study |
|
https://doi.org/10.18632/oncotarget.10303
|
| 57317-57326 |
Reviews
|
| Epimutational profile of hematologic malignancies as attractive target for new epigenetic therapies |
|
https://doi.org/10.18632/oncotarget.10033
|
| 57327-57350 |
|
| uPA/uPAR and SERPINE1 in head and neck cancer: role in tumor resistance metastasis prognosis and therapy |
|
https://doi.org/10.18632/oncotarget.10344
|
| 57351-57366 |
|
| Local hyperthermia in head and neck cancer: mechanism application and advance |
|
https://doi.org/10.18632/oncotarget.10350
|
| 57367-57378 |
|
| LncRNAs in pancreatic cancer |
|
https://doi.org/10.18632/oncotarget.10545
|
| 57379-57390 |
|
| Necroptosis in tumorigenesis activation of antitumor immunity and cancer therapy |
|
https://doi.org/10.18632/oncotarget.10548
|
| 57391-57413 |
|
| NETs: organrelated epigenetic derangements and potential clinical applications |
|
https://doi.org/10.18632/oncotarget.10598
|
| 57414-57429 |
|
| Progress and perspective of TBX6 gene in congenital vertebral malformations |
|
https://doi.org/10.18632/oncotarget.10619
|
| 57430-57441 |
|
| Potential role of the NMYC downstreamregulated gene family in reprogramming cancer metabolism under hypoxia |
|
https://doi.org/10.18632/oncotarget.10684
|
| 57442-57451 |
|
| Epigenetics in myeloid derived suppressor cells: a sheathed sword towards cancer |
|
https://doi.org/10.18632/oncotarget.10767
|
| 57452-57463 |
|
| Genetic polymorphisms of mTOR and cancer risk: a systematic review and updated metaanalysis |
|
https://doi.org/10.18632/oncotarget.10805
|
| 57464-57480 |
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