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About The Cover
The cover for issue 52 of Oncotarget features Figure 3, “Comparable affordability of 8 patented cancer drugs in 7 countries,” from Goldstein, et al., originally published in N42. Please see today’s editorial about that paper from Gyawali.
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Table of Contents
Editorial
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| Cancer drugs in LMICs: cheap but unaffordable |
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https://doi.org/10.18632/oncotarget.21976
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| 89425-89426 |
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| Ribosomal proteins: a novel class of oncogenic drivers |
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https://doi.org/10.18632/oncotarget.20802
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| 89427-89428 |
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| HO1 inhibits migration of leukemic cells |
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https://doi.org/10.18632/oncotarget.21044
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| 89429-89430 |
Research Papers: Gerotarget (Focus on Aging)
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| TSHindependent release of thyroid hormones through cold exposure in aging rats |
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https://doi.org/10.18632/oncotarget.19851
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| 89431-89438 |
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| E3 ligase mahogunin MGRN1 influences amyloid precursor protein maturation and secretion |
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https://doi.org/10.18632/oncotarget.20143
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| 89439-89450 |
Research Papers: Pathology
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| BMAL1 facilitates trophoblast migration and invasion via SP1DNMT1/DAB2IP pathway in recurrent spontaneous abortion |
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https://doi.org/10.18632/oncotarget.20702
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| 89451-89464 |
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| PDL1 expression and CD8+ tumorinfiltrating lymphocytes are associated with ALK rearrangement and clinicopathological features in inflammatory myofibroblastic tumors |
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https://doi.org/10.18632/oncotarget.20948
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| 89465-89474 |
Research Papers: Immunology
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| Inhibition of autoimmune Th17 cell responses by pain killer ketamine |
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https://doi.org/10.18632/oncotarget.18324
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| 89475-89485 |
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| B cells regulate thymic CD8+T cell differentiation in lupusprone mice |
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https://doi.org/10.18632/oncotarget.19002
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| 89486-89499 |
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| Epigallocatechin3gallate EGCG upregulates miR15b expression thus attenuating store operated calcium entry SOCE into murine CD4+ T cells and human leukaemic T cell lymphoblasts |
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https://doi.org/10.18632/oncotarget.20032
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| 89500-89514 |
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| Immunology repertoire study of pulmonary sarcoidosis T cells in CD4+ CD8+ PBMC and tissue |
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https://doi.org/10.18632/oncotarget.20085
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| 89515-89526 |
Research Papers: Autophagy and Cell Death
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| Inhibitor of growth protein 4 interacts with Beclin 1 and represses autophagy |
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https://doi.org/10.18632/oncotarget.19033
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| 89527-89538 |
Research Papers
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| YAP1 is essential for tumor growth and is a potential therapeutic target for EGFRdependent lung adenocarcinomas |
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https://doi.org/10.18632/oncotarget.19647
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| 89539-89551 |
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| Role of microenvironmental periostin in pancreatic cancer progression |
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https://doi.org/10.18632/oncotarget.11533
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| 89552-89565 |
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| Inhibition of HOX/PBX dimer formation leads to necroptosis in acute myeloid leukemia cells |
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https://doi.org/10.18632/oncotarget.20023
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| 89566-89579 |
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| Increased cFLIP expression in thymic epithelial tumors blocks autophagy via NFκB signalling |
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https://doi.org/10.18632/oncotarget.15929
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| 89580-89594 |
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| Tumor response of temozolomide in combination with morphine in a xenograft model of human glioblastoma |
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https://doi.org/10.18632/oncotarget.19875
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| 89595-89606 |
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| Integrative analysis of novel hypomethylation and gene expression signatures in glioblastomas |
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https://doi.org/10.18632/oncotarget.19171
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| 89607-89619 |
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| Loss of Sun2 promotes the progression of prostate cancer by regulating fatty acid oxidation |
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https://doi.org/10.18632/oncotarget.19210
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| 89620-89630 |
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| MiR1268b confers chemosensitivity in breast cancer by targeting ERBB2mediated PI3KAKT pathway |
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https://doi.org/10.18632/oncotarget.20099
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| 89631-89642 |
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| DHX15 is associated with poor prognosis in acute myeloid leukemia AML and regulates cell apoptosis via the NFkB signaling pathway |
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https://doi.org/10.18632/oncotarget.20288
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| 89643-89654 |
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| A study on the expression of apoptotic molecules related to death receptor and endoplasmic reticulum pathways in the jejunum of AFB1intoxicated chickens |
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https://doi.org/10.18632/oncotarget.20333
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| 89655-89664 |
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| Maternal dietary manganese protects chick embryos against maternal heat stress via epigeneticactivated antioxidant and antiapoptotic abilities |
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https://doi.org/10.18632/oncotarget.20804
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| 89665-89680 |
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| Hypoxiainducible factor1α activation in HPVpositive head and neck squamous cell carcinoma cell lines |
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https://doi.org/10.18632/oncotarget.20813
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| 89681-89691 |
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| SYNJ2BP promotes the degradation of PTEN through the lysosomepathway and enhances breast tumor metastasis via PI3K/AKT/SNAI1 signaling |
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https://doi.org/10.18632/oncotarget.21058
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| 89692-89706 |
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| BMI1 reduces ATR activation and signalling caused by hydroxyurea |
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https://doi.org/10.18632/oncotarget.21111
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| 89707-89721 |
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| Abundant expression of TIM3 LAG3 PD1 and PDL1 as immunotherapy checkpoint targets in effusions of mesothelioma patients |
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https://doi.org/10.18632/oncotarget.21113
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| 89722-89735 |
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| IMP2/IGF2BP2 expression but not IMP1 and IMP3 predicts poor outcome in patients and high tumor growth rate in xenograft models of gallbladder cancer |
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https://doi.org/10.18632/oncotarget.21116
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| 89736-89745 |
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| TM5441 a plasminogen activator inhibitor1 inhibitor protects against high fat dietinduced nonalcoholic fatty liver disease |
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https://doi.org/10.18632/oncotarget.21120
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| 89746-89760 |
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| Axl inhibition induces the antitumor immune response which can be further potentiated by PD1 blockade in the mouse cancer models |
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https://doi.org/10.18632/oncotarget.21125
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| 89761-89774 |
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| Neural crest derived progenitor cells contribute to tumor stroma and aggressiveness in stage 4/M neuroblastoma |
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https://doi.org/10.18632/oncotarget.21128
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| 89775-89792 |
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| MIND417 protects retinal pigment epithelium cells and retinal ganglion cells from UV |
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https://doi.org/10.18632/oncotarget.21131
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| 89793-89801 |
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| Prostaglandin E2 and PD1 mediated inhibition of antitumor CTL responses in the human tumor microenvironment |
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https://doi.org/10.18632/oncotarget.21155
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| 89802-89810 |
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| A combination of circulating miRNAs for the early detection of ovarian cancer |
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https://doi.org/10.18632/oncotarget.20688
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| 89811-89823 |
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| Abnormal CYP11A1 gene expression induces excessive autophagy contributing to the pathogenesis of preeclampsia |
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https://doi.org/10.18632/oncotarget.21158
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| 89824-89836 |
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| Dualtargeting nanoparticles with excellent gene transfection efficiency for gene therapy of peritoneal metastasis of colorectal cancer |
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https://doi.org/10.18632/oncotarget.21159
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| 89837-89847 |
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| Rapid ultra low coverage copy number profiling of cellfree DNA as a precision oncology screening strategy |
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https://doi.org/10.18632/oncotarget.21163
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| 89848-89866 |
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| Association of FOXF2 gene polymorphisms with ischemic stroke in Chinese Han population |
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https://doi.org/10.18632/oncotarget.21263
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| 89867-89875 |
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| Oral 4Nstearoyl gemcitabine nanoparticles inhibit tumor growth in mouse models |
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https://doi.org/10.18632/oncotarget.21264
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| 89876-89886 |
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| Plasminogen activator inhibitor1 is an independent prognostic factor of ovarian cancer and IMD4482 a novel plasminogen activator inhibitor1 inhibitor inhibits ovarian cancer peritoneal dissemination |
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https://doi.org/10.18632/oncotarget.20834
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| 89887-89902 |
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| PDL1 expression on immune cells is a favorable prognostic factor for vulvar squamous cell carcinoma patients |
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https://doi.org/10.18632/oncotarget.20911
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| 89903-89912 |
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| MicroRNA1443p inhibits bone formation in distraction osteogenesis through targeting Connexin 43 |
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https://doi.org/10.18632/oncotarget.20984
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| 89913-89922 |
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| JAK2 aberrations in childhood Bcell precursor acute lymphoblastic leukemia |
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https://doi.org/10.18632/oncotarget.21027
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| 89923-89938 |
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| Endoflife care in children with hematologic malignancies |
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https://doi.org/10.18632/oncotarget.21188
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| 89939-89948 |
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| Long noncoding RNA CCAT1 modulates neuropathic pain progression through sponging miR155 |
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https://doi.org/10.18632/oncotarget.21192
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| 89949-89957 |
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| Evaluation of somatostatin CXCR4 chemokine and endothelin A receptor expression in a large set of paragangliomas |
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https://doi.org/10.18632/oncotarget.21194
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| 89958-89969 |
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| HAT1 induces lung cancer cell apoptosis via up regulating Fas |
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https://doi.org/10.18632/oncotarget.21205
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| 89970-89977 |
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| Circulating tumor cells as liquid biomarker for high HCC recurrence risk after curative liver resection |
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https://doi.org/10.18632/oncotarget.21208
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| 89978-89987 |
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| Thymine DNA Glycosylase TDG is involved in the pathogenesis of intestinal tumors with reduced APC expression |
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https://doi.org/10.18632/oncotarget.21219
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| 89988-89997 |
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| Interferoninducible CXCchemokines are crucial immune modulators and survival predictors in colorectal cancer |
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https://doi.org/10.18632/oncotarget.21286
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| 89998-90012 |
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| Macitentan a double antagonist of endothelin receptors efficiently impairs migration and microenvironmental survival signals in chronic lymphocytic leukemia |
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https://doi.org/10.18632/oncotarget.21341
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| 90013-90027 |
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| CD4+T cell specific B7H1 selectively inhibits proliferation of naïve T cells and Th17 differentiation in experimental autoimmune encephalomyelitis |
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https://doi.org/10.18632/oncotarget.21357
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| 90028-90036 |
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| Distinct signaling events promote resistance to mitoxantrone and etoposide in pediatric AML: a Children’s Oncology Group report |
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https://doi.org/10.18632/oncotarget.21363
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| 90037-90049 |
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| Myeloid ecotropic viral integration site 1 inhibits cell proliferation invasion or migration in human gastric cancer |
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https://doi.org/10.18632/oncotarget.21376
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| 90050-90060 |
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| Impaired GABABmediated presynaptic inhibition increases excitatory strength and alters shortterm plasticity in synapsin knockout mice |
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https://doi.org/10.18632/oncotarget.21405
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| 90061-90076 |
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| Identification of metastasisassociated microRNAs in serum from rectal cancer patients |
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https://doi.org/10.18632/oncotarget.21412
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| 90077-90089 |
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| The novel ZIP4 regulation and its role in ovarian cancer |
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https://doi.org/10.18632/oncotarget.21435
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| 90090-90107 |
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| Multivalent cationic pseudopeptide polyplexes as a tool for cancer therapy |
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https://doi.org/10.18632/oncotarget.21441
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| 90108-90122 |
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| PDL1 expression heterogeneity in nonsmall cell lung cancer: evaluation of small biopsies reliability |
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https://doi.org/10.18632/oncotarget.21485
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| 90123-90131 |
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| Sestrin2 and sestrin3 suppress NK92 cellmediated cytotoxic activity on ovarian cancer cells through AMPK and mTORC1 signaling |
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https://doi.org/10.18632/oncotarget.21487
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| 90132-90143 |
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| Characteristics and genetic diversity of multidrug resistant extendedspectrum betalactamase ESBLproducing Escherichia coli isolated from bovine mastitis |
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https://doi.org/10.18632/oncotarget.21496
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| 90144-90163 |
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| Pediatric brain tumor cells release exosomes with a miRNA repertoire that differs from exosomes secreted by normal cells |
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https://doi.org/10.18632/oncotarget.21621
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| 90164-90175 |
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| Exploring the model of PC12 apoptosis induced by OGSD/R through in vitro experiments |
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https://doi.org/10.18632/oncotarget.21623
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| 90176-90184 |
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| Role of drugdependent transporter modulation on the chemosensitivity of cholangiocarcinoma |
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https://doi.org/10.18632/oncotarget.21624
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| 90185-90196 |
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| The clinical use of circulating microRNAs as noninvasive diagnostic biomarkers for lung cancers |
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https://doi.org/10.18632/oncotarget.21644
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| 90197-90214 |
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| Structural basis of the therapeutic antiPDL1 antibody atezolizumab |
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https://doi.org/10.18632/oncotarget.21652
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| 90215-90224 |
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| MYC is downregulated by a mitochondrial checkpoint mechanism |
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https://doi.org/10.18632/oncotarget.21653
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| 90225-90237 |
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| Targeting cyclophilinD by compound 19 protects neuronal cells from oxygen glucose deprivation/reoxygenation |
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https://doi.org/10.18632/oncotarget.21655
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| 90238-90249 |
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| Maternal histone acetyltransferase KAT8 is required for porcine preimplantation embryo development |
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https://doi.org/10.18632/oncotarget.21657
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| 90250-90261 |
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| HDAC inhibitors enhance neratinib activity and when combined enhance the actions of an antiPD1 immunomodulatory antibody in vivo |
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https://doi.org/10.18632/oncotarget.21660
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| 90262-90277 |
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| Fluorescence contrastenhanced proliferative lesion imaging by enema administration of indocyanine green in a rat model of colon carcinogenesis |
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https://doi.org/10.18632/oncotarget.21744
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| 90278-90290 |
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| Surrogate endpoint for overall survival in assessment of adjuvant therapies after curative treatment for hepatocellular carcinoma: a reanalysis of metaanalyses of individual patients’ data |
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https://doi.org/10.18632/oncotarget.18853
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| 90291-90300 |
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| Metaanalysis of the prognostic value of lncRNA ZFAS1 in patients with solid tumors |
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https://doi.org/10.18632/oncotarget.19566
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| 90301-90307 |
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| Systematic review and metaanalysis comparing zoledronic acid administered at 12week and 4week intervals in patients with bone metastasis |
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https://doi.org/10.18632/oncotarget.19856
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| 90308-90314 |
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| MUC1 overexpression predicts worse survival in patients with nonsmall cell lung cancer: evidence from an updated metaanalysis |
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https://doi.org/10.18632/oncotarget.19861
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| 90315-90326 |
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| Neoadjuvant chemotherapy followed by surgery versus upfront surgery in nonmetastatic nonsmall cell lung cancer: systematic review and metaanalysis of randomized controlled trials |
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https://doi.org/10.18632/oncotarget.20044
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| 90327-90337 |
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| A systematic review and metaanalysis of effectiveness and safety of therapy for overactive bladder using botulinum toxin A at different dosages |
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https://doi.org/10.18632/oncotarget.20056
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| 90338-90350 |
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| Prognostic value of cMet overexpression in hepatocellular carcinoma: a metaanalysis and review |
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https://doi.org/10.18632/oncotarget.20087
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| 90351-90357 |
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| CD147 expression was positively linked to aggressiveness and worse prognosis of gastric cancer: a meta and bioinformatics analysis |
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https://doi.org/10.18632/oncotarget.20089
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| 90358-90370 |
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| Kinetics of plasma von Willebrand factor in acute myocardial infarction patients: a metaanalysis |
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https://doi.org/10.18632/oncotarget.20091
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| 90371-90379 |
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| The use of neutrophil to lymphocyte ratio as a predictor for clinical outcomes in spontaneous intracerebral hemorrhage |
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https://doi.org/10.18632/oncotarget.20120
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| 90380-90389 |
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| Combining desgammacarboxyprothrombin and alphafetoprotein for hepatocellular carcinoma diagnosing: an update metaanalysis and validation study |
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https://doi.org/10.18632/oncotarget.20153
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| 90390-90401 |
Clinical Research Papers
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| Prognostic value of intratumoral metabolic heterogeneity on F18 fluorodeoxyglucose positron emission tomography/computed tomography in locally advanced cervical cancer patients treated with concurrent chemoradiotherapy |
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https://doi.org/10.18632/oncotarget.18769
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| 90402-90412 |
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| An improved nervesparing radical hysterectomy technique for cervical cancer using the paravesicovaginal space as a new surgical landmark |
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https://doi.org/10.18632/oncotarget.19011
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| 90413-90420 |
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| Assessing right ventricular function in pulmonary hypertension patients and the correlation with the New York Heart Association NYHA classification |
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https://doi.org/10.18632/oncotarget.19026
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| 90421-90429 |
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| Realworld experience of afatinib as a firstline therapy for advanced EGFR mutationpositive lung adenocarcinoma |
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https://doi.org/10.18632/oncotarget.19563
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| 90430-90443 |
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| Effect of subclinical hypothyroidism on the skeletal system and improvement with shortterm thyroxine therapy |
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https://doi.org/10.18632/oncotarget.19568
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| 90444-90451 |
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| Identifying current and remitted major depressive disorder with the Hurst exponent: a comparative study on two automated anatomical labeling atlases |
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https://doi.org/10.18632/oncotarget.19860
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| 90452-90464 |
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| Improved medical expenditure and survival with integration of traditional Chinese medicine treatment in patients with heart failure: A nationwide populationbased cohort study |
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https://doi.org/10.18632/oncotarget.20063
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| 90465-90476 |
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| Does the type of anesthesia really affect the recurrencefree survival after breast cancer surgery |
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https://doi.org/10.18632/oncotarget.21014
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| 90477-90487 |
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| A relative increase in circulating platelets following chemoradiation predicts for poor survival of patients with glioblastoma |
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https://doi.org/10.18632/oncotarget.21799
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| 90488-90495 |
Reviews
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| Radiation therapy and serum salivary amylase in head and neck cancer |
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https://doi.org/10.18632/oncotarget.18763
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| 90496-90500 |
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| The therapeutic potential of cell cycle targeting in multiple myeloma |
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https://doi.org/10.18632/oncotarget.18765
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| 90501-90520 |
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| Chimericantigen receptor T CART cell therapy for solid tumors: challenges and opportunities |
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https://doi.org/10.18632/oncotarget.19361
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| 90521-90531 |
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| Checkpoint inhibitors in endometrial cancer: preclinical rationale and clinical activity |
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https://doi.org/10.18632/oncotarget.20042
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| 90532-90544 |
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| Melatonin as a potential inhibitory agent in head and neck cancer |
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https://doi.org/10.18632/oncotarget.20079
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| 90545-90556 |
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| Mechanisms of resistance to irreversible epidermal growth factor receptor tyrosine kinase inhibitors and therapeutic strategies in nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.21164
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| 90557-90578 |
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| Interactions between TGFβ1 canonical WNT/βcatenin pathway and PPAR γ in radiationinduced fibrosis |
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https://doi.org/10.18632/oncotarget.21234
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| 90579-90604 |
Corrections
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| Correction: Compliance with the enhanced recovery after surgery protocol and prognosis after colorectal cancer surgery: A prospective cohort study |
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https://doi.org/10.18632/oncotarget.22102
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| 90605-90605 |
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Oncotarget ® is a registered trademark of Rapamycin Press LLC
Impact Journals ® is a registered trademark of Rapamycin Press LLC
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