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The cover for issue 34 of Oncotarget features Figure 3C, "SMYD2-mediated β-catenin methylation is required for expression of Wnt downstream genes and β-catenin nuclear translocation by FOXM1," from Deng, et al.

Table of Contents

News

Fledglings in p53 signaling network

https://doi.org/10.18632/oncotarget.19229

Takashi Tokino, Masashi Idogawa, and Yasushi Sasaki
55768-55769
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Editorial

PRRT2 a network stability gene

https://doi.org/10.18632/oncotarget.19506

Caterina Michetti, Anna Corradi, and Fabio Benfenati
55770-55771
Abstract  |  PDF  |  How to cite

Transglutaminase in neurological disease

https://doi.org/10.18632/oncotarget.19694

Guylaine Hoffner, and Philippe Djian
55772-55773
Abstract  |  PDF  |  How to cite

Cancer’s new Achilles’ heel

https://doi.org/10.18632/oncotarget.19954

Gareth I. Owen
55774-55775
Abstract  |  PDF  |  How to cite

Priority Research Papers

Dicer suppresses cytoskeleton remodeling and tumorigenesis of colorectal epithelium by miR3245p mediated suppression of HMGXB3 and WASF2

https://doi.org/10.18632/oncotarget.18218

Li Na Sun, Cheng Xing, Zheng Zhi, Yao Liu, Liang-Yan Chen, Tong Shen, Qun Zhou, Yu Hong Liu, Wen Juan Gan, Jing-Ru Wang, Yong Xu, and Jian Ming Li
55776-55789
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification of a novel p53 target COL17A1 that inhibits breast cancer cell migration and invasion

https://doi.org/10.18632/oncotarget.18433

Varalee Yodsurang, Chizu Tanikawa, Takafumi Miyamoto, Paulisally Hau Yi Lo, Makoto Hirata, and Koichi Matsuda
55790-55803
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Resistance to CTLA4 checkpoint inhibition reversed through selective elimination of granulocytic myeloid cells

https://doi.org/10.18632/oncotarget.18437

Paul E. Clavijo, Ellen C. Moore, Jianhong Chen, Ruth J. Davis, Jay Friedman, Young Kim, Carter Van Waes, Zhong Chen, and Clint T. Allen
55804-55820
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Identification of a p53repressed gene module in breast cancer cells

https://doi.org/10.18632/oncotarget.19608

Takafumi Miyamoto, Chizu Tanikawa, Varalee Yodsurang, Yao-Zhong Zhang, Seiya Imoto, Rui Yamaguchi, Satoru Miyano, Hidewaki Nakagawa, and Koichi Matsuda
55821-55836
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Critical roles of SMYD2mediated βcatenin methylation for nuclear translocation and activation of Wnt signaling

https://doi.org/10.18632/oncotarget.19646

Xiaolan Deng, Ryuji Hamamoto, Theodore Vougiouklakis, Rui Wang, Yuichiro Yoshioka, Takehiro Suzuki, Naoshi Dohmae, Yo Matsuo, Jae-Hyun Park, and Yusuke Nakamura
55837-55847
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Loss of p16INK4A stimulates aberrant mitochondrial biogenesis through a CDK4/Rbindependent pathway

https://doi.org/10.18632/oncotarget.19862

Ethika Tyagi, Bin Liu, Chelsea Li, Tong Liu, Jared Rutter, and Douglas Grossman
55848-55862
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Domain analysis reveals striking functional differences between the regulatory subunits of phosphatidylinositol 3kinase PI3K p85α and p85β

https://doi.org/10.18632/oncotarget.19866

Yoshihiro Ito, Peter K. Vogt, and Jonathan R. Hart
55863-55876
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Priority Research Papers: Immunology

Zbtb1 controls NKp46+ RORgammaT+ innate lymphoid cell ILC3 development

https://doi.org/10.18632/oncotarget.19645

Ying Lu, Xianyu Zhang, Nicolas Bouladoux, Saransh Neel Kaul, Kangxin Jin, Derek Sant’Angelo, Yasmine Belkaid, and Damian Kovalovsky
55877-55888
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Gerotarget (Focus on Aging)

Pharynx mitochondrial [Ca2+] dynamics in live C elegans worms during aging

https://doi.org/10.18632/oncotarget.18600

Pilar Alvarez-Illera, Paloma García-Casas, Jessica Arias-del-Val, Rosalba I. Fonteriz, Javier Alvarez, and Mayte Montero
55889-55900
Abstract  |  PDF  |  Full Text  |  How to cite

Differentially expressed lncRNAs and miRNAs with associated ceRNA networks in aged mice with postoperative cognitive dysfunction

https://doi.org/10.18632/oncotarget.18362

Changwei Wei, Ting Luo, Shanshan Zou, Xiaobin Zhou, Wenzhen Shen, Xiaolin Ji, Qi Li, and Anshi Wu
55901-55914
Abstract  |  PDF  |  Full Text  |  How to cite

Detecting the genetic link between Alzheimer’s disease and obesity using bioinformatics analysis of GWAS data

https://doi.org/10.18632/oncotarget.19115

Qi-Shuai Zhuang, Hao Zheng, Xiao-Dan Gu, Liang Shen, and Hong-Fang Ji
55915-55919
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers: Pathology

NiaoDuQing granules relieve chronic kidney disease symptoms by decreasing renal fibrosis and anemia

https://doi.org/10.18632/oncotarget.18473

Xu Wang, Suyun Yu, Qi Jia, Lichuan Chen, Jinqiu Zhong, Yanhong Pan, Peiliang Shen, Yin Shen, Siliang Wang, Zhonghong Wei, Yuzhu Cao, and Yin Lu
55920-55937
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Classical swine fever virus Shimen infection increases p53 signaling to promote cell cycle arrest in porcine alveolar macrophages

https://doi.org/10.18632/oncotarget.18997

Pengbo Ning, Congxia Hu, Xuepeng Li, Yulu Zhou, Aoxue Hu, Ya Zhang, Lifang Gao, Cunmei Gong, Kangkang Guo, Xianghan Zhang, and Yanming Zhang
55938-55949
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PKCθ utility in diagnosing cKIT/DOG1 double negative gastrointestinal stromal tumors

https://doi.org/10.18632/oncotarget.19116

Attila Kövecsi, Ioan Jung, Zoltan Szentirmay, Tivadar Bara, Tivadar Bara Jr, Daniel Popa, and Simona Gurzu
55950-55957
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers: Immunology

Synergistic antibiotic effect of looped antimicrobial peptide CLP19 with bactericidal and bacteriostatic agents

https://doi.org/10.18632/oncotarget.18124

Di Li, Ya Yang, Zhiqiang Tian, Jun Lv, Fengjun Sun, Qian Wang, Yao Liu, and Peiyuan Xia
55958-55966
Abstract  |  PDF  |  Full Text  |  How to cite

Melatonin inhibits Sirt1dependent NAMPT and NFAT5 signaling in chondrocytes to attenuate osteoarthritis

https://doi.org/10.18632/oncotarget.18356

Jia Yi Guo, Feng Li, Yong Bing Wen, Hong Xun Cui, Ma Long Guo, Lin Zhang, Yun Fei Zhang, Yan Jin Guo, and Yan Xing Guo
55967-55983
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers: Autophagy and Cell Death

Hyperosmotic stress stimulates autophagy via polycystin2

https://doi.org/10.18632/oncotarget.18995

Daniel Peña-Oyarzun, Rodrigo Troncoso, Catalina Kretschmar, Cecilia Hernando, Mauricio Budini, Eugenia Morselli, Sergio Lavandero, and Alfredo Criollo
55984-55997
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

GABARAPL1 tumor suppressive function is independent of its conjugation to autophagosomes in MCF7 breast cancer cells

https://doi.org/10.18632/oncotarget.19639

Laura Poillet-Perez, Marine Jacquet, Eric Hervouet, Thierry Gauthier, Annick Fraichard, Christophe Borg, Jean-René Pallandre, Bruno J. Gonzalez, Yasmina Ramdani, Michaël Boyer-Guittaut, Régis Delage-Mourroux, and Gilles Despouy
55998-56020
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers

IL1 genes polymorphism and the risk of renal cell carcinoma in Chinese Han population

https://doi.org/10.18632/oncotarget.18715

Fei Wang, Yingai Zhang, Shunlan Wang, Yadong Zhang, Dinglan Wu, Chong Zhang, Yuanhui Gao, Xi Liu, Weifu Wang, and Shufang Zhang
56021-56029
Abstract  |  PDF  |  Full Text  |  How to cite

P62 plasmid can alleviate dietinduced obesity and metabolic dysfunctions

https://doi.org/10.18632/oncotarget.19840

Tatiana Halenova, Oleksii Savchuk, Ludmila Ostapchenko, Andrey Chursov, Nathan Fridlyand, Andrey B. Komissarov, Franco Venanzi, Sergey I. Kolesnikov, Albert A. Sufianov, Michael Y. Sherman, Vladimir L. Gabai, and Alexander M. Shneider
56030-56040
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Downregulation of NTCP expression by cyclin D1 in hepatitis B virusrelated hepatocellular carcinoma has clinical significance

https://doi.org/10.18632/oncotarget.10241

Jingting Kang, Jie Wang, Jin Cheng, Zhiliang Cao, Ran Chen, Huiyu Li, Shuang Liu, Xiangmei Chen, Jianhua Sui, and Fengmin Lu
56041-56050
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade

https://doi.org/10.18632/oncotarget.17359

Thomas W. Flaig, Maren Salzmann-Sullivan, Lih-Jen Su, Zhiyong Zhang, Molishree Joshi, Miguel A. Gijón, Jihye Kim, John J. Arcaroli, Adrie Van Bokhoven, M. Scott Lucia, Francisco G. La Rosa, and Isabel R. Schlaepfer
56051-56065
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite
Special Collection ToC

Comparative study of whole genome amplification and next generation sequencing performance of single cancer cells

https://doi.org/10.18632/oncotarget.10701

Anna Babayan, Malik Alawi, Michael Gormley, Volkmar Müller, Harriet Wikman, Ryan P. McMullin, Denis A. Smirnov, Weimin Li, Maria Geffken, Klaus Pantel, and Simon A. Joosse
56066-56080
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Hexokinase 2 promotes tumor growth and metastasis by regulating lactate production in pancreatic cancer

https://doi.org/10.18632/oncotarget.9760

Marybeth Anderson, Raoud Marayati, Richard Moffitt, and Jen Jen Yeh
56081-56094
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Hepatic B cell leukemia3 suppresses chemicallyinduced hepatocarcinogenesis in mice through altered MAPK and NFκB activation

https://doi.org/10.18632/oncotarget.10893

Nadine Gehrke, Marcus A. Wörns, Amrit Mann, Yvonne Huber, Nadine Hoevelmeyer, Thomas Longerich, Ari Waisman, Peter R. Galle, and Jörn M. Schattenberg
56095-56109
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Vorinostat suppresses hypoxia signaling by modulating nuclear translocation of hypoxia inducible factor 1 alpha

https://doi.org/10.18632/oncotarget.18125

Chao Zhang, Chunzhang Yang, Michael J. Feldman, Herui Wang, Ying Pang, Dominic M. Maggio, Dongwang Zhu, Cody L. Nesvick, Pauline Dmitriev, Petra Bullova, Prashant Chittiboina, Roscoe O. Brady, Karel Pacak, and Zhengping Zhuang
56110-56125
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Targeting hypoxic cancer stem cells CSCs with Doxycycline: Implications for optimizing antiangiogenic therapy

https://doi.org/10.18632/oncotarget.18445

Ernestina Marianna De Francesco, Marcello Maggiolini, Herbert B. Tanowitz, Federica Sotgia, and Michael P. Lisanti
56126-56142
Abstract  |  PDF  |  Full Text  |  How to cite

MicroRNA profiling associated with nonsmall cell lung cancer: next generation sequencing detection experimental validation and prognostic value

https://doi.org/10.18632/oncotarget.18603

Sandra Gallach, Eloisa Jantus-Lewintre, Silvia Calabuig-Fariñas, David Montaner, Sergio Alonso, Rafael Sirera, Ana Blasco, Marta Usó, Ricardo Guijarro, Miguel Martorell, and Carlos Camps
56143-56157
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Molecular and functional characterization of a new 3′ end KIT juxtamembrane deletion in a duodenal GIST treated with neoadjuvant Imatinib

https://doi.org/10.18632/oncotarget.19341

Vittorio Perfetti, Erik Laurini, Suzana Aulić, Maurizio Fermeglia, Roberta Riboni, Marco Lucioni, Elena Dallera, Sara Delfanti, Luigi Pugliese, Francesco Saverio Latteri, Andrea Pietrabissa, and Sabrina Pricl
56158-56167
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Upregulation of LINC00161 correlates with tumor migration and invasion and poor prognosis of patients with hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.17040

Li-Chao Xu, Quan-Ning Chen, Xi-Qiang Liu, Xiao-Ming Wang, Qi-Meng Chang, Qi Pan, Lu Wang, and Yi-Lin Wang
56168-56173
Abstract  |  PDF  |  Full Text  |  How to cite

MicroRNA610 suppresses osteosarcoma oncogenicity via targeting TWIST1 expression

https://doi.org/10.18632/oncotarget.17045

Chi Jin, Yongjian Feng, Yongjian Ni, and Zhonglin Shan
56174-56184
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

NAcetylcysteine breaks resistance to trastuzumab caused by MUC4 overexpression in human HER2 positive BCbearing nude mice monitored by 89ZrTrastuzumab and 18FFDG PET imaging

https://doi.org/10.18632/oncotarget.17015

Zéna Wimana, Geraldine Gebhart, Thomas Guiot, Bruno Vanderlinden, Denis Larsimont, Gilles Doumont, Gaetan Van Simaeys, Serge Goldman, Patrick Flamen, and Ghanem Ghanem
56185-56198
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A phase 1 doseescalation study of the oral histone deacetylase inhibitor abexinostat in combination with standard hypofractionated radiotherapy in advanced solid tumors

https://doi.org/10.18632/oncotarget.14147

Eric Deutsch, Elizabeth Cohen-Jonathan Moyal, Vanesa Gregorc, Paolo Andrea Zucali, Jean Menard, Jean-Charles Soria, Ioana Kloos, Jeff Hsu, Ying Luan, Emily Liu, Remus Vezan, Thorsten Graef, and Sofia Rivera
56199-56209
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Time dependent modulation of tumor radiosensitivity by a pan HDAC inhibitor: abexinostat

https://doi.org/10.18632/oncotarget.14813

Sofia Rivera, Céline Leteur, Frédérique Mégnin, Frédéric Law, Isabelle Martins, Ioana Kloos, Stéphane Depil, Nazanine Modjtahedi, Jean Luc Perfettini, Christophe Hennequin, and Eric Deutsch
56210-56227
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Hepatitis C virus core protein targets 4EBP1 expression and phosphorylation and potentiates Mycinduced liver carcinogenesis in transgenic mice

https://doi.org/10.18632/oncotarget.17280

Cosette Abdallah, Charlène Lejamtel, Nassima Benzoubir, Serena Battaglia, Nazha Sidahmed-Adrar, Christophe Desterke, Matthieu Lemasson, Arielle R. Rosenberg, Didier Samuel, Christian Bréchot, Delphine Pflieger, François Le Naour, and Marie-Françoise Bourgeade
56228-56242
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Expression and release of glucoseregulated protein78 GRP78 in multiple myeloma

https://doi.org/10.18632/oncotarget.17353

Normann Steiner, Bojana Borjan, Roman Hajek, Karin Jöhrer, Georg Göbel, Wolfgang Willenbacher, Johann Kern, Eberhard Gunsilius, and Gerold Untergasser
56243-56254
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

FoxR2 promotes glioma proliferation by suppression of the p27 pathway

https://doi.org/10.18632/oncotarget.17447

Xuejiao Liu, Ning Liu, Chenglong Yue, Dacheng Wang, Zhenglei Qi, Yiming Tu, Guokun Zhuang, Di Zhou, Shangfeng Gao, Mingshan Niu, and Rutong Yu
56255-56266
Abstract  |  PDF  |  Full Text  |  How to cite

Casticin attenuates liver fibrosis and hepatic stellate cell activation by blocking TGFβ/Smad signaling pathway

https://doi.org/10.18632/oncotarget.17453

Ling Zhou, Xiaoying Dong, Linlin Wang, Lanlan Shan, Ting Li, Wanfu Xu, Yan Ding, Mingqiang Lai, Xiaojun Lin, Meng Dai, Xiaochun Bai, Chunhong Jia, and Hang Zheng
56267-56280
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Combination of DESI2 and IP10 gene therapy significantly improves therapeutic efficacy against murine carcinoma

https://doi.org/10.18632/oncotarget.17623

Chao Lin, HuaYing Yan, Jun Yang, Lei Li, Mei Tang, Xinyu Zhao, Chunlai Nie, Na Luo, Yuquan Wei, and Zhu Yuan
56281-56295
Abstract  |  PDF  |  Full Text  |  How to cite

Eugenol alleviated breast precancerous lesions through HER2/ PI3KAKT pathwayinduced cell apoptosis and Sphase arrest

https://doi.org/10.18632/oncotarget.17626

Min Ma, Yi Ma, Gui-Juan Zhang, Rui Liao, Xue-Feng Jiang, Xian-Xin Yan, Feng-Jie Bie, Xiao-Bo Li, and Yan-Hong Lv
56296-56310
Abstract  |  PDF  |  Full Text  |  How to cite

Targeted alpha therapy using a novel CD70 targeted thorium227 conjugate in in vitro and in vivo models of renal cell carcinoma

https://doi.org/10.18632/oncotarget.16910

Urs B. Hagemann, Dessislava Mihaylova, Steinar R. Uran, Joergen Borrebaek, Derek Grant, Roger M. Bjerke, Jenny Karlsson, and Alan S. Cuthbertson
56311-56326
Abstract  |  PDF  |  Full Text  |  How to cite

A novel EGFRTKI inhibitor cAMPH3BO3 complex combined with thermal therapy is a promising strategy to improve lung cancer treatment outcomes

https://doi.org/10.18632/oncotarget.17628

Yongpeng Tong, Chunliu Huang, and Junfang Zhang
56327-56337
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification of precision treatment strategies for relapsed/ refractory multiple myeloma by functional drug sensitivity testing

https://doi.org/10.18632/oncotarget.17630

Muntasir Mamun Majumder, Raija Silvennoinen, Pekka Anttila, David Tamborero, Samuli Eldfors, Bhagwan Yadav, Riikka Karjalainen, Heikki Kuusanmäki, Juha Lievonen, Alun Parsons, Minna Suvela, Esa Jantunen, Kimmo Porkka, and Caroline A. Heckman
56338-56350
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Baicalein inhibits pancreatic cancer cell proliferation and invasion via suppression of NEDD9 expression and its downstream Akt and ERK signaling pathways

https://doi.org/10.18632/oncotarget.16912

Rong-Tao Zhou, Mei He, Ze Yu, Yang Liang, Yuzhe Nie, Sheng Tai, and Chun-Bo Teng
56351-56363
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Androgen receptor expression identifies patient with favorable outcome in operable triple negative breast cancer

https://doi.org/10.18632/oncotarget.16913

Xiao-Qing Hu, Wei-Li Chen, Hai-Guang Ma, and Ke Jiang
56364-56374
Abstract  |  PDF  |  Full Text  |  How to cite

IL8 promotes inflammatory mediators and stimulates activation of p38 MAPK/ERKNFκB pathway and reduction of JNK in HNSCC

https://doi.org/10.18632/oncotarget.16914

Leong-Perng Chan, Cheng Liu, Feng-Yu Chiang, Ling-Feng Wang, Ka-Wo Lee, Wan-Ting Chen, Po-Lin Kuo, and Chia-Hua Liang
56375-56388
Abstract  |  PDF  |  Full Text  |  How to cite

Urine miR215p as a potential noninvasive biomarker for gastric cancer

https://doi.org/10.18632/oncotarget.16916

Hsiao-Wei Kao, Chao-Yu Pan, Chun-Hung Lai, Chew-Wun Wu, Wen-Liang Fang, Kuo-Hung Huang, and Wen-Chang Lin
56389-56397
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Copy number variations of circulating cellfree DNA in urothelial carcinoma of the bladder patients treated with radical cystectomy: a prospective study

https://doi.org/10.18632/oncotarget.17657

Armin Soave, Felix K.H. Chun, Timo Hillebrand, Michael Rink, Lars Weisbach, Bettina Steinbach, Margit Fisch, Klaus Pantel, and Heidi Schwarzenbach
56398-56407
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tumor vasculogenic mimicry formation as an unfavorable prognostic indicator in patients with breast cancer

https://doi.org/10.18632/oncotarget.16919

Yanwei Shen, Jianfeng Quan, Mengying Wang, Shuting Li, Jiao Yang, Meng Lv, Zheling Chen, Lingxiao Zhang, Xiaoai Zhao, and Jin Yang
56408-56416
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR148a impairs Ras/ERK signaling in B lymphocytes by targeting SOS proteins

https://doi.org/10.18632/oncotarget.17662

Julia Alles, Nicole Ludwig, Stefanie Rheinheimer, Petra Leidinger, Friedrich A. Grässer, Andreas Keller, and Eckart Meese
56417-56427
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Increased expression of calponin 2 is a positive prognostic factor in pancreatic ductal adenocarcinoma

https://doi.org/10.18632/oncotarget.17701

Zhaoyan Qiu, Yi Chu, Bing Xu, Qian Wang, Mingzuo Jiang, Xiaowei Li, Gang Wang, Pengfei Yu, Guoxiao Liu, Hua Wang, Huijie Kang, Jiayu Liu, Yu Zhang, Jian-Ping Jin, Kaichun Wu, and Jie Liang
56428-56442
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Estrogen promotes tumor metastasis via estrogen receptor betamediated regulation of matrixmetalloproteinase2 in nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.16992

Sheng Fan, Yongde Liao, Changyu Liu, Quanfu Huang, Huifang Liang, Bo Ai, Shegnling Fu, and Sheng Zhou
56443-56459
Abstract  |  PDF  |  Full Text  |  How to cite

Overexpression of a functional calciumsensing receptor dramatically increases osteolytic potential of MDAMB231 cells in a mouse model of bone metastasis through epiregulinmediated osteoprotegerin downregulation

https://doi.org/10.18632/oncotarget.16999

Cédric Boudot, Lucie Hénaut, Ursula Thiem, Sandra Geraci, Mariangela Galante, Paulo Saldanha, Zuzana Saidak, Isabelle Six, Philippe Clézardin, Said Kamel, and Romuald Mentaverri
56460-56472
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

HSP90 inhibitor 17DMAG exerts anticancer effects against gastric cancer cells principally by altering oxidantantioxidant balance

https://doi.org/10.18632/oncotarget.17007

Jeong Goo Kim, Sang Chul Lee, Ok-Hee Kim, Kee-Hwan Kim, Kyo Young Song, Sang Kuon Lee, Byung Jo Choi, Wonjun Jeong, and Say-June Kim
56473-56489
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Proteolytic cleavages in the extracellular domain of receptor tyrosine kinases by membraneassociated serine proteases

https://doi.org/10.18632/oncotarget.17009

Li-Mei Chen, and Karl X. Chai
56490-56505
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Coal tar pitch extract could induce chromosomal instability of human bronchial epithelial cells mediated by spindle checkpointrelated proteins

https://doi.org/10.18632/oncotarget.17025

Peng Zhang, Zhitao Li, Na Wang, Guangcai Duan, Wei Wang, Yanming Feng, Yong Zhao, Lixia Wang, Hansong Zhu, Qiao Zhang, Xiaozhuan Liu, Weidong Wu, Yongjun Wu, Wu Yao, Jing Wang, Yiming Wu, and Feifei Feng
56506-56517
Abstract  |  PDF  |  Full Text  |  How to cite

A genomewide microRNA profiling indicates miR4245p and miR5035p as regulators of ALK expression in neuroblastoma

https://doi.org/10.18632/oncotarget.17033

Marilena De Mariano, Sara Stigliani, Stefano Moretti, Federica Parodi, Michela Croce, Cinzia Bernardi, Aldo Pagano, Gian Paolo Tonini, Silvano Ferrini, and Luca Longo
56518-56532
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Polymorphisms of primiR2191 are associated with the susceptibility and prognosis of nonsmall cell lung cancer in a Northeast Chinese population

https://doi.org/10.18632/oncotarget.17035

Chang Zheng, Xuelian Li, Lingzi Xia, Xue Fang, Xiaowei Quan, Zhihua Yin, Yuxia Zhao, and Baosen Zhou
56533-56541
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR451 as a new tumor marker for gastric cancer

https://doi.org/10.18632/oncotarget.17239

Yong Shen, Jiao-Mei Gong, Li-Li Zhou, and Jia-He Sheng
56542-56545
Abstract  |  PDF  |  Full Text  |  How to cite

Metformin increases chemosensitivity via gene downregulation encoding DNA replication proteins in 5Fu resistant colorectal cancer cells

https://doi.org/10.18632/oncotarget.17798

Sung-Hee Kim, Soon-Chan Kim, and Ja-Lok Ku
56546-56557
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The roles of ING5 in gliomas: a good marker for tumorigenesis and a potential target for gene therapy

https://doi.org/10.18632/oncotarget.17802

Shuang Zhao, Zhi-Juan Zhao, Hao-Yu He, Ji-Cheng Wu, Xiao-Qing Ding, Lei Yang, Ning Jia, Zhi-Jie Li, and Hua-Chuan Zheng
56558-56568
Abstract  |  PDF  |  Full Text  |  How to cite

Alternative promotion and suppression of metastasis by JNK2 governed by its phosphorylation

https://doi.org/10.18632/oncotarget.17507

Sike Hu, Xiaoli Dong, Wenjuan Gao, Dwayne Stupack, Yanhua Liu, Rong Xiang, and Na Li
56569-56581
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Mitochondrial protein 18 MTP18 plays a proapoptotic role in chemotherapyinduced gastric cancer cell apoptosis

https://doi.org/10.18632/oncotarget.17508

Lynn H.H. Aung, Ruibei Li, Bellur S. Prabhakar, Ajay V. Maker, and Peifeng Li
56582-56597
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Expression of CD38 in myeloma bone niche: A rational basis for the use of antiCD38 immunotherapy to inhibit osteoclast formation

https://doi.org/10.18632/oncotarget.17896

Federica Costa, Denise Toscani, Antonella Chillemi, Valeria Quarona, Marina Bolzoni, Valentina Marchica, Rosanna Vescovini, Cristina Mancini, Eugenia Martella, Nicoletta Campanini, Chiara Schifano, Sabrina Bonomini, Fabrizio Accardi, Alberto L. Horenstein, Franco Aversa, Fabio Malavasi, and Nicola Giuliani
56598-56611
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

TDP43/HDAC6 axis promoted tumor progression and regulated nutrient deprivationinduced autophagy in glioblastoma

https://doi.org/10.18632/oncotarget.17979

Tzu-Wei Lin, Ming-Teh Chen, Liang-Tin Lin, Pin-I Huang, Wen-Liang Lo, Yi-Ping Yang, Kai-Hsi Lu, Yi-Wei Chen, Shih-Hwa Chiou, and Cheng-Wen Wu
56612-56625
Abstract  |  PDF  |  Full Text  |  How to cite

Predictive factors of pathologic complete response in HER2positive and axillary lymph node positive breast cancer after neoadjuvant paclitaxel carboplatin plus with trastuzumab

https://doi.org/10.18632/oncotarget.17993

Jinhua Ding, Yinlong Yang, Li Jiang, Weizhu Wu, and Zhiming Shao
56626-56634
Abstract  |  PDF  |  Full Text  |  How to cite

Suppression of miR16 promotes tumor growth and metastasis through reversely regulating YAP1 in human cholangiocarcinoma

https://doi.org/10.18632/oncotarget.17832

Sheng Han, Dong Wang, Guohua Tang, Xinxiang Yang, Chenyu Jiao, Renjie Yang, Yaodong Zhang, Liqun Huo, Zicheng Shao, Zefa Lu, Jiawei Zhang, and Xiangcheng Li
56635-56650
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Autosomal InDel polymorphisms for population genetic structure and differentiation analysis of Chinese Kazak ethnic group

https://doi.org/10.18632/oncotarget.17838

Tingting Kong, Yahao Chen, Yuxin Guo, Yuanyuan Wei, Xiaoye Jin, Tong Xie, Yuling Mu, Qian Dong, Shaoqing Wen, Boyan Zhou, Li Zhang, Chunmei Shen, and Bofeng Zhu
56651-56658
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PRPF overexpression induces drug resistance through actin cytoskeleton rearrangement and epithelialmesenchymal transition

https://doi.org/10.18632/oncotarget.17855

Salman Ul Islam, Adeeb Shehzad, Jong Kyung Sonn, and Young Sup Lee
56659-56671
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Wip1 is associated with tumorigenity and metastasis through MMP2 in human intrahepatic cholangiocarcinoma

https://doi.org/10.18632/oncotarget.18074

Sulai Liu, Bo Jiang, Hao Li, Zili He, Pin Lv, Chuang Peng, Yonggang Wang, Wei Cheng, Zhengquan Xu, Wei Chen, Zhengkai Liu, Bao Zhang, Shengqian Shen, and Shuanglin Xiang
56672-56683
Abstract  |  PDF  |  Full Text  |  How to cite

Genomic analysis–integrated wholeexome sequencing of neuroblastomas identifies genetic mutations in axon guidance pathway

https://doi.org/10.18632/oncotarget.18079

Yuanyuan Li, Miki Ohira, Yong Zhou, Teng Xiong, Wen Luo, Chao Yang, Xiangchun Li, Zhibo Gao, Rui Zhou, Yohko Nakamura, Takehiko Kamijo, Yasuhiko Kaneko, Takeshi Taketani, Junichi Ueyama, Tatsuro Tajiri, Hongyan Zhang, Jian Wang, Huanming Yang, Ye Yin, and Akira Nakagawara
56684-56697
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Inhibition of the PI3K/AKT/mTOR pathway activates autophagy and compensatory Ras/Raf/MEK/ERK signalling in prostate cancer

https://doi.org/10.18632/oncotarget.18082

Dominika E. Butler, Christopher Marlein, Hannah F. Walker, Fiona M. Frame, Vincent M. Mann, Matthew S. Simms, Barry R. Davies, Anne T. Collins, and Norman J. Maitland
56698-56713
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite
Special Collection ToC

Microwave ablation combined with EGFRTKIs versus only EGFRTKIs in advanced NSCLC patients with EGFRsensitive mutations

https://doi.org/10.18632/oncotarget.18083

Zhigang Wei, Xin Ye, Xia Yang, Aimin Zheng, Guanghui Huang, Wenhong Li, Jiao Wang, Xiaoying Han, Min Meng, and Yang Ni
56714-56725
Abstract  |  PDF  |  Full Text  |  How to cite

Longterm cigarette smoke exposure inhibits histone deacetylase 2 expression and enhances the nuclear factorκB activation in skeletal muscle of mice

https://doi.org/10.18632/oncotarget.18089

Dongmei Huang, Zhiying Ma, Yili He, Ying Xiao, Honglin Luo, Qiuli Liang, Xiaoning Zhong, Jing Bai, and Zhiyi He
56726-56736
Abstract  |  PDF  |  Full Text  |  How to cite

HDLcholesterol concentration in pregnant Chinese Han women of late second trimester associated with genetic variants in CETP ABCA1 APOC3 and GALNT2

https://doi.org/10.18632/oncotarget.18128

Mingxuan Cui, Wei Li, Liangkun Ma, Fan Ping, Juntao Liu, Xueyan Wu, Jiangfeng Mao, Xi Wang, and Min Nie
56737-56746
Abstract  |  PDF  |  Full Text  |  How to cite

Panobinostat a histone deacetylase inhibitor suppresses leptomeningeal seeding in a medulloblastoma animal model

https://doi.org/10.18632/oncotarget.18132

Ji Hoon Phi, Seung Ah Choi, Pil Ae Kwak, Ji Yeoun Lee, Kyu-Chang Wang, Do Won Hwang, and Seung-Ki Kim
56747-56757
Abstract  |  PDF  |  Full Text  |  How to cite

Clinicopathological and prognostic significance of cMet overexpression in breast cancer

https://doi.org/10.18632/oncotarget.18142

Xixi Zhao, Jingkun Qu, Yuxin Hui, Hong Zhang, Yuchen Sun, Xu Liu, Xiaoyao Zhao, Zitong Zhao, Qian Yang, Feidi Wang, and Shuqun Zhang
56758-56767
Abstract  |  PDF  |  Full Text  |  How to cite

IER3IP1 deficiency leads to increased βcell death and decreased βcell proliferation

https://doi.org/10.18632/oncotarget.18179

Juan Sun, and Decheng Ren
56768-56779
Abstract  |  PDF  |  Full Text  |  How to cite

CASP8 652 6N insertion/deletion polymorphism and overall cancer risk: evidence from 49 studies

https://doi.org/10.18632/oncotarget.18187

Jiarong Cai, Qingjian Ye, Suling Luo, Ze Zhuang, Kui He, Zhen-Jian Zhuo, Xiaochun Wan, and Juan Cheng
56780-56790
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

In vivo autophagy and biogenesis of autophagosomes within male haploid cells during spermiogenesis

https://doi.org/10.18632/oncotarget.18221

Ping Yang, Nisar Ahmed, Lingling Wang, Hong Chen, Yasir Waqas, Tengfei Liu, Abdul Haseeb, Nasrullah Bangulzai, Yufei Huang, and Qiusheng Chen
56791-56801
Abstract  |  PDF  |  Full Text  |  How to cite

Decitabine inhibits T cell proliferation via a novel TET2dependent mechanism and exerts potent protective effect in mouse auto and alloimmunity models

https://doi.org/10.18632/oncotarget.18063

Xue Wang, Jun Wang, Yong Yu, Tonghui Ma, Ping Chen, Bing Zhou, and Ran Tao
56802-56815
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Selection of optimal molecular targets for tumorspecific imaging in pancreatic ductal adenocarcinoma

https://doi.org/10.18632/oncotarget.18232

Willemieke S. Tummers, Arantza Farina-Sarasqueta, Martin C. Boonstra, Hendrica A. Prevoo, Cornelis F. Sier, Jan S. Mieog, Johannes Morreau, Casper H. van Eijck, Peter J. Kuppen, Cornelis J. van de Velde, Bert A. Bonsing, Alexander L. Vahrmeijer, and Rutger-Jan Swijnenburg
56816-56828
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

DNA methylation signature of long noncoding RNA genes during human preimplantation embryonic development

https://doi.org/10.18632/oncotarget.18072

Jingyu Li, Wei Han, Xiaoli Shen, Shubiao Han, Hong Ye, and Guoning Huang
56829-56838
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Dysregulation of an Xlinked primatespecific epididymal microRNA cluster in unexplained asthenozoospermia

https://doi.org/10.18632/oncotarget.18076

Xingrong Qing, Jian Shi, Tingting Dong, Chunlin Wu, Lian Hu, and Honggang Li
56839-56849
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Role of glucose metabolism related gene GLUT1 in the occurrence and prognosis of colorectal cancer

https://doi.org/10.18632/oncotarget.18090

Wenming Feng, Ge Cui, Cheng-wu Tang, Xiao-lan Zhang, Chuang Dai, Yong-qiang Xu, Hui Gong, Tao Xue, Hui-hui Guo, and Ying Bao
56850-56857
Abstract  |  PDF  |  Full Text  |  How to cite

BTK suppresses myeloma cellular senescence through activating AKT/P27/Rb signaling

https://doi.org/10.18632/oncotarget.18096

Chunyan Gu, Hailin Peng, Yue Lu, Hongbao Yang, Zhidan Tian, Gang Yin, Wen Zhang, Sicheng Lu, Yi Zhang, and Ye Yang
56858-56867
Abstract  |  PDF  |  Full Text  |  How to cite

Oleoylethanolamide inhibits αmelanocyte stimulating hormonestimulated melanogenesis via ERK Akt and CREB signaling pathways in B16 melanoma cells

https://doi.org/10.18632/oncotarget.18097

Juan Zhou, Tong Ren, Ying Li, Anran Cheng, Wanyi Xie, Lanxi Xu, Lu Peng, Jinbin Lin, Lianxiang Lian, Yong Diao, Xin Jin, and Lichao Yang
56868-56879
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Heptamethine carbocyanine DZ1 dye for nearinfrared fluorescence imaging of hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.18131

Jiaze An, Ningning Zhao, Caiqin Zhang, Yong Zhao, Dengxu Tan, Ya Zhao, Bing Bai, Hai Zhang, Boyang Jason Wu, and Changhong Shi
56880-56892
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Marsdenia tenacissima extract overcomes Axl and Metmediated erlotinib and gefitinib crossresistance in nonsmall cell lung cancer cells

https://doi.org/10.18632/oncotarget.18137

Shu-Yan Han, Wei Zhao, Hai-Bo Han, Hong Sun, Dong Xue, Yan-Na Jiao, Xi-Ran He, Shan-Tong Jiang, and Ping-Ping Li
56893-56905
Abstract  |  PDF  |  Full Text  |  How to cite

Reevaluation of ATR signaling in primary resting chronic lymphocytic leukemia cells: evidence for prosurvival or proapoptotic function

https://doi.org/10.18632/oncotarget.18144

Maxime Beyaert, Eliza Starczewska, Ana Cristina González Pérez, Nicolas Vanlangendonck, Pascale Saussoy, Gaëlle Tilman, Anne De Leener, Marie-Christiane Vekemans, Eric Van Den Neste, and Françoise Bontemps
56906-56920
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A retrospective multicentric observational study of trastuzumab emtansine in HER2 positive metastatic breast cancer: a realworld experience

https://doi.org/10.18632/oncotarget.18176

Patrizia Vici, Laura Pizzuti, Andrea Michelotti, Isabella Sperduti, Clara Natoli, Lucia Mentuccia, Luigi Di Lauro, Domenico Sergi, Paolo Marchetti, Daniele Santini, Emanuela Magnolfi, Laura Iezzi, Luca Moscetti, Agnese Fabbri, Alessandra Cassano, Antonino Grassadonia, Claudia Omarini, Federico Piacentini, Andrea Botticelli, Ilaria Bertolini, Angelo Fedele Scinto, Germano Zampa, Maria Mauri, Loretta D’Onofrio, Valentina Sini, Maddalena Barba, Marcello Maugeri-Saccà, Ernesto Rossi, Elisabetta Landucci, Silverio Tomao, Antonio Maria Alberti, Francesco Giotta, Corrado Ficorella, Vincenzo Adamo, Antonio Russo, Vito Lorusso, Katia Cannita, Sandro Barni, Lucio Laudadio, Filippo Greco, Ornella Garrone, Marina Della Giulia, Paolo Marolla, Giuseppe Sanguineti, Barbara Di Cocco, Gennaro Ciliberto, Ruggero De Maria, and Teresa Gamucci
56921-56931
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Relationship between the TERT TNIP1 and OBFC1 genetic polymorphisms and susceptibility to colorectal cancer in Chinese Han population

https://doi.org/10.18632/oncotarget.18378

Chuang Li, Zixuan Zhao, Jun Zhou, Ying Liu, Hao Wang, and Xinhan Zhao
56932-56941
Abstract  |  PDF  |  Full Text  |  How to cite

Phytoagent deoxyelephantopin derivative inhibits triple negative breast cancer cell activity by inducing oxidative stressmediated paraptosislike cell death

https://doi.org/10.18632/oncotarget.18183

Jeng-Yuan Shiau, Kyoko Nakagawa-Goto, Kuo-Hsiung Lee, and Lie-Fen Shyur
56942-56958
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

SOCS1 gene promoter methylation status is associated with instent restenosis after percutaneous coronary intervention

https://doi.org/10.18632/oncotarget.18398

Liang Zhou, Ningfu Wang, Hong Li, Guoxin Tong, Jianmin Yang, Lei Lai, Hao Pan, Xianhua Ye, and Jinyu Huang
56959-56967
Abstract  |  PDF  |  Full Text  |  How to cite

Interleukin15 stimulates natural killer cellmediated killing of both human pancreatic cancer and stellate cells

https://doi.org/10.18632/oncotarget.18185

Jonas R.M. Van Audenaerde, Jorrit De Waele, Elly Marcq, Jinthe Van Loenhout, Eva Lion, Johan M.J. Van den Bergh, Ralf Jesenofsky, Atsushi Masamune, Geert Roeyen, Patrick Pauwels, Filip Lardon, Marc Peeters, and Evelien L.J. Smits
56968-56979
Abstract  |  PDF  |  Full Text  |  How to cite

Necroptosis as a potential therapeutic target in multiple organ dysfunction syndrome

https://doi.org/10.18632/oncotarget.18252

Yao-Li Cui, Li-Hua Qiu, Shi-Yong Zhou, Lan-Fang Li, Zheng-Zi Qian, Xian-Ming Liu, Hui-Lai Zhang, Xiu-Bao Ren, and Yong-Qiang Wang
56980-56990
Abstract  |  PDF  |  Full Text  |  How to cite

Synergistic suppression of t8;21positive leukemia cell growth by combining oridonin and MAPK1/ERK2 inhibitors

https://doi.org/10.18632/oncotarget.18503

Pavel Spirin, Timofey Lebedev, Natalia Orlova, Alexey Morozov, Nadezhda Poymenova, Sergey E Dmitriev, Anton Buzdin, Carol Stocking, Olga Kovalchuk, and Vladimir Prassolov
56991-57002
Abstract  |  PDF  |  Full Text  |  How to cite

Digoxininduced anemia among patients with atrial fibrillation and heart failure: clinical data analysis and druggene interaction network

https://doi.org/10.18632/oncotarget.18504

Yubi Lin, Siqi He, Ruiling Feng, Zhe Xu, Wanqun Chen, Zifeng Huang, Yang Liu, Qianhuan Zhang, Bin Zhang, Kejian Wang, and Shulin Wu
57003-57011
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MicroRNA1075p suppresses nonsmall cell lung cancer by directly targeting oncogene epidermal growth factor receptor

https://doi.org/10.18632/oncotarget.18505

Ping Wang, Xiaomin Liu, Yang Shao, Huimin Wang, Chen Liang, Baohui Han, and Zhongliang Ma
57012-57023
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Programmed differentiated natural killer cells kill leukemia cells by engaging SLAM family receptors

https://doi.org/10.18632/oncotarget.18659

Yang Wu, Young Li, Binqing Fu, Linlin Jin, Xiaohu Zheng, Aimei Zhang, Rui Sun, Zhigang Tian, and Haiming Wei
57024-57038
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PLD1 overexpression promotes invasion and migration and function as a risk factor for Chinese glioma patients

https://doi.org/10.18632/oncotarget.18961

Wenjun Tang, Richu Liang, Yonghong Duan, Qiaoling Shi, Xiaofei Liu, and Yongshi Liao
57039-57046
Abstract  |  PDF  |  Full Text  |  How to cite

Dual targeting of MDM2 and BCL2 as a therapeutic strategy in neuroblastoma

https://doi.org/10.18632/oncotarget.18982

Alan Van Goethem, Nurten Yigit, Myrthala Moreno-Smith, Sanjeev A. Vasudevan, Eveline Barbieri, Frank Speleman, Jason Shohet, Jo Vandesompele, and Tom Van Maerken
57047-57057
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Daurinol blocks breast and lung cancer metastasis and development by inhibition of focal adhesion kinase FAK

https://doi.org/10.18632/oncotarget.18983

Jong Kyu Woo, Hyun Jin Jung, Ji-Youn Park, Ju-Hee Kang, Byung Il Lee, Dong Yun Shin, Chu Won Nho, Soo-Young Cho, Je Kyung Seong, and Seung Hyun Oh
57058-57071
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Notch system is differentially expressed and activated in pituitary adenomas of distinct histotype tumor cell lines and normal pituitaries

https://doi.org/10.18632/oncotarget.19046

Sofia Perrone, Lautaro Zubeldia-Brenner, Elias Gazza, Gianina Demarchi, Leticia Baccarini, Agustin Baricalla, Freya Mertens, Guillermina Luque, Hugo Vankelecom, Silvia Berner, Damasia Becu-Villalobos, and Carolina Cristina
57072-57088
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Patterns and clinical significance of cervical lymph node metastasis in papillary thyroid cancer patients with Delphian lymph node metastasis

https://doi.org/10.18632/oncotarget.19047

Guibin Zheng, Hua Zhang, Shaolong Hao, Chengxin Liu, Jie Xu, Jinyao Ning, Guochang Wu, Lixin Jiang, Guojun Li, Haitao Zheng, and Xicheng Song
57089-57098
Abstract  |  PDF  |  Full Text  |  How to cite

The prevalence subtypes and associated factors of hyperuricemia in lupus nephritis patients at chronic kidney disease stages 1–3

https://doi.org/10.18632/oncotarget.19051

Simeng Liu, Yijun Gong, Hong Ren, Wen Zhang, Xiaonong Chen, Tong Zhou, Xiao Li, and Nan Chen
57099-57108
Abstract  |  PDF  |  Full Text  |  How to cite

Oxidative stress mediates an increased formation of vascular endothelial growth factor in human hepatocarcinoma cells exposed to erlotinib

https://doi.org/10.18632/oncotarget.19055

Nataliya Rohr-Udilova, Florian Klinglmüller, Martha Seif, Hubert Hayden, Martin Bilban, Matthias Pinter, Klaus Stolze, Wolfgang Sieghart, Markus Peck-Radosavljevic, and Michael Trauner
57109-57120
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Datadriven analysis of immune infiltrate in a large cohort of breast cancer and its association with disease progression ER activity and genomic complexity

https://doi.org/10.18632/oncotarget.19078

Ruth Dannenfelser, Marianne Nome, Andliena Tahiri, Josie Ursini-Siegel, Hans Kristian Moen Vollan, Vilde D. Haakensen, Åslaug Helland, Bjørn Naume, Carlos Caldas, Anne-Lise Børresen-Dale, Vessela N. Kristensen, and Olga G. Troyanskaya
57121-57133
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Mass spectrometrybased assay for the molecular diagnosis of glioma: concomitant detection of chromosome 1p/19q codeletion and IDH1 IDH2 and TERT mutation status

https://doi.org/10.18632/oncotarget.19103

Chiara Pesenti, Leda Paganini, Laura Fontana, Emanuela Veniani, Letterio Runza, Stefano Ferrero, Silvano Bosari, Maura Menghi, Giovanni Marfia, Manuela Caroli, Rosamaria Silipigni, Silvana Guerneri, Silvia Tabano, and Monica Miozzo
57134-57148
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Small molecular floribundiquinone B derived from medicinal plants inhibits acetylcholinesterase activity

https://doi.org/10.18632/oncotarget.19169

Bing Niu, Mengying Zhang, Pu Du, Li Jiang, Rui Qin, Qiang Su, Fuxue Chen, Dongshu Du, Yilai Shu, and Kuo-Chen Chou
57149-57162
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Cblb predicts postoperative survival in patients with resectable pancreatic ductal adenocarcinoma

https://doi.org/10.18632/oncotarget.18714

Qian Dong, Yuteng Ma, Yao Zhang, Xiujuan Qu, Zhi Li, Yafei Qi, Yunpeng Liu, Ce Li, Kai Li, Xianghong Yang, and Xiaofang Che
57163-57173
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR2233p inhibits angiogenesis and promotes resistance to cetuximab in head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.19170

Alexandre Bozec, Joséphine Zangari, Mathilde Butori-Pepino, Marius Ilie, Salomé Lalvee, Thierry Juhel, Catherine Butori, Patrick Brest, Paul Hofman, and Valérie Vouret-Craviari
57174-57186
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Morusin inhibits cell proliferation and tumor growth by downregulating cMyc in human gastric cancer

https://doi.org/10.18632/oncotarget.19231

Feng Wang, Dunke Zhang, Jingxin Mao, Xiao-Xue Ke, Rui Zhang, Chao Yin, Ning Gao, and Hongjuan Cui
57187-57200
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The ketogenic diet is not feasible as a therapy in a CD1 nu/nu mouse model of renal cell carcinoma with features of Stauffer’s syndrome

https://doi.org/10.18632/oncotarget.19306

Silvia Vidali, Sepideh Aminzadeh-Gohari, René Günther Feichtinger, Renaud Vatrinet, Andreas Koller, Felix Sternberg, Tricia Rutherford, Maura O’Donnell, Andrea Stöger-Kleiber, Bridget Lambert, Thomas Klaus Felder, Wolfgang Sperl, and Barbara Kofler
57201-57215
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ARD1mediated aurora kinase A acetylation promotes cell proliferation and migration

https://doi.org/10.18632/oncotarget.19332

Tam Thuy Lu Vo, Ji-Hyeon Park, Ji Hae Seo, Eun Ji Lee, Hoon Choi, Sung-Jin Bae, Hoang Le, Sunho An, Hye Shin Lee, Hee-Jun Wee, and Kyu-Won Kim
57216-57230
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Assessment of nearinfrared fluorophores to study the biodistribution and tumor targeting of an IL13 receptor α2 antibody by fluorescence molecular tomography

https://doi.org/10.18632/oncotarget.19569

Parul Gupta, Jo-Ann Wentland, Mauricio Leal, Dangshe Ma, Rachel Roach, Antonio Esparza, Lindsay King, Mary E. Spilker, Cedo Bagi, Christopher T. Winkelmann, and Anand Giddabasappa
57231-57245
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

NSC30049 inhibits Chk1 pathway in 5FUresistant CRC bulk and stem cell populations

https://doi.org/10.18632/oncotarget.19778

Satya Narayan, Aruna S. Jaiswal, Ritika Sharma, Akbar Nawab, Lizette Vila Duckworth, Brian K. Law, Maria Zajac-Kaye, Thomas J. George, Jay Sharma, Arun K. Sharma, and Robert A. Hromas
57246-57264
Abstract  |  PDF  |  Full Text  |  How to cite

Folate metabolism genetic polymorphisms and meningioma and glioma susceptibility in adults

https://doi.org/10.18632/oncotarget.18986

Dongming Chen, Jun Dong, Ying Huang, Feng Gao, Xiaopeng Yang, Xianglun Gong, Xiaochen Lv, Chenghao Chu, Yonggang Wu, and Yong Zheng
57265-57277
Abstract  |  PDF  |  Full Text  |  How to cite

Prostate cancer diagnosis using epigenetic biomarkers 3D highcontent imaging and probabilistic cellbycell classifiers

https://doi.org/10.18632/oncotarget.18985

Darko Stefanovski, George Tang, Kolja Wawrowsky, Raymond C. Boston, Nils Lambrecht, and Jian Tajbakhsh
57278-57301
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Integration of ALV into CTDSPL and CTDSPL2 genes in Bcell lymphomas promotes cell immortalization migration and survival

https://doi.org/10.18632/oncotarget.19328

Shelby Winans, Alyssa Flynn, Sanandan Malhotra, Vidya Balagopal, and Karen L. Beemon
57302-57315
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Meta-Analysis

An updated metaanalysis of amantadine for treating dyskinesia in Parkinson’s disease

https://doi.org/10.18632/oncotarget.17622

Min Kong, Maowen Ba, Chao Ren, Ling Yu, Shengjie Dong, Guoping Yu, and Hui Liang
57316-57326
Abstract  |  PDF  |  Full Text  |  How to cite

Prognositic value of CD73adenosinergic pathway in solid tumor: A metaanalysis and systematic review

https://doi.org/10.18632/oncotarget.16905

Rong Wang, Yingying Zhang, Xia Lin, Yalin Gao, and Ying Zhu
57327-57336
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Bevacizumab combined with chemotherapy for glioblastoma: a metaanalysis of randomized controlled trials

https://doi.org/10.18632/oncotarget.16924

Shou-Bo Yang, Kai-Di Gao, Tao Jiang, Shu-Jun Cheng, and Wen-Bin Li
57337-57344
Abstract  |  PDF  |  Full Text  |  How to cite

Association of apelin and apelin receptor with the risk of coronary artery disease: a metaanalysis of observational studies

https://doi.org/10.18632/oncotarget.17360

Tianbao Chen, Bing Wu, and Rong Lin
57345-57355
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinical outcomes of WBRT plus EGFRTKIs versus WBRT or TKIs alone for the treatment of cerebral metastatic NSCLC patients: a metaanalysis

https://doi.org/10.18632/oncotarget.19054

Hong Zheng, Quan-Xing Liu, Bin Hou, Dong Zhou, Jing-Meng Li, Xiao Lu, Qiu-Ping Wu, and Ji-Gang Dai
57356-57364
Abstract  |  PDF  |  Full Text  |  How to cite

Docetaxel versus docetaxel plus cisplatin for nonsmallcell lung cancer: a metaanalysis of randomized clinical trials

https://doi.org/10.18632/oncotarget.17071

Ang Li, Zhi-Jian Wei, Han Ding, Hao-Shuai Tang, Heng-Xing Zhou, Xue Yao, and Shi-Qing Feng
57365-57378
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Metaanalysis of the incidence and risks of interstitial lung disease and QTc prolongation in nonsmallcell lung cancer patients treated with ALK inhibitors

https://doi.org/10.18632/oncotarget.18283

Liping Lin, Juanjuan Zhao, Ning Kong, Yan He, Jiazhu Hu, Fuxi Huang, Jianjun Han, and Xiaolong Cao
57379-57385
Abstract  |  PDF  |  Full Text  |  How to cite

Prognostic role of tumorinfiltrating lymphocytes in gastric cancer: a metaanalysis

https://doi.org/10.18632/oncotarget.18065

Xiao Zheng, Xing Song, Yingjie Shao, Bin Xu, Lujun Chen, Qi Zhou, Wenwei Hu, Dachuan Zhang, Changping Wu, Min Tao, Yibei Zhu, and Jingting Jiang
57386-57398
Abstract  |  PDF  |  Full Text  |  How to cite

Combination therapy versus pharmacotherapy endoscopic variceal ligation or the transjugular intrahepatic portosystemic shunt alone in the secondary prevention of esophageal variceal bleeding: a metaanalysis of randomized controlled trials

https://doi.org/10.18632/oncotarget.18143

Lu-Lu Lin, Shi-Ming Du, Yan Fu, Hui-Yun Gu, Lei Wang, Zhi-Yuan Jian, Xian-Feng Shen, Jie Luo, and Chao Zhang
57399-57408
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Association of P73 polymorphisms with susceptibilities of cervical carcinoma: a metaanalysis

https://doi.org/10.18632/oncotarget.18164

Xianghua Liang, Bingxiang Chen, and Jianxin Zhong
57409-57413
Abstract  |  PDF  |  Full Text  |  How to cite

Systematic review and metaanalysis of the efficacy of breast conservation therapy followed by radiotherapy in four breast cancer subtypes

https://doi.org/10.18632/oncotarget.18205

Xin-Bin Pan, Rou-Jun Chen, Shi-Ting Huang, Yan-Ming Jiang, and Xiao-Dong Zhu
57414-57420
Abstract  |  PDF  |  Full Text  |  How to cite

Association between 8q24 rs6983267 polymorphism and cancer susceptibility: a metaanalysis involving 170737 subjects

https://doi.org/10.18632/oncotarget.18960

Man Zhu, Xue Wen, Xuefang Liu, Yingchao Wang, Chunzi Liang, and Jiancheng Tu
57421-57439
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Lack of association between NAT2 polymorphism and prostate cancer risk: a metaanalysis and trial sequential analysis

https://doi.org/10.18632/oncotarget.19023

Feng Wang, Zhiqiang Qin, Shuhui Si, Jingyuan Tang, Lingyan Xu, Haoxiang Xu, Ran Li, Peng Han, and Haiwei Yang
57440-57450
Abstract  |  PDF  |  Full Text  |  How to cite

Clinical Research Papers

BACH2 promotes indolent clinical presentation in Waldenström macroglobulinemia

https://doi.org/10.18632/oncotarget.9917

Charles Herbaux, Elisabeth Bertrand, Guillemette Marot, Christophe Roumier, Nicolas Poret, Valérie Soenen, Olivier Nibourel, Catherine Roche-Lestienne, Natacha Broucqsault, Sylvie Galiègue-Zouitina, Eileen M Boyle, Guillemette Fouquet, Aline Renneville, Sabine Tricot, Franck Morschhauser, Claude Preudhomme, Bruno Quesnel, Stephanie Poulain, and Xavier Leleu
57451-57459
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prognostic significance of neutrophiltolymphocyte ratio in patients with malignant pleural mesothelioma: a metaanalysis

https://doi.org/10.18632/oncotarget.15404

Nan Chen, Shuai Liu, Lin Huang, Wanling Li, Wenhao Yang, Tianxin Cong, Lin Ding, and Meng Qiu
57460-57469
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Evaluation on efficacy and safety of the addition of Xknife therapy to gefitinib in NSCLC patients with symptomatic brain metastases

https://doi.org/10.18632/oncotarget.10420

Linbo Cai, Xiaoguang Qiu, Haihong Yang, Mingyao Lai, Changguo Shan, Weiping Hong, Juan Li, Longhui Luo, Ping Zhang, and Lichao Wang
57470-57476
Abstract  |  PDF  |  Full Text  |  How to cite

Features and risk factors of carotid atherosclerosis in a population with high stroke incidence in China

https://doi.org/10.18632/oncotarget.15415

Yanqiu Zhang, Lingling Bai, Min Shi, Hongyan Lu, Yanan Wu, Jun Tu, Jingxian Ni, Jinghua Wang, Li Cao, Ping Lei, and Xianjia Ning
57477-57488
Abstract  |  PDF  |  Full Text  |  How to cite

Neutrophiltolymphocyte ratio and neurological deterioration following acute cerebral hemorrhage

https://doi.org/10.18632/oncotarget.15423

Simona Lattanzi, Claudia Cagnetti, Leandro Provinciali, and Mauro Silvestrini
57489-57494
Abstract  |  PDF  |  Full Text  |  How to cite

Different longterm oncologic outcomes after radical surgical resection for neuroendocrine carcinoma and adenocarcinoma of the stomach

https://doi.org/10.18632/oncotarget.15488

Jian-Wei Xie, Jun Lu, Jian-Xian Lin, Chao-Hui Zheng, Ping Li, Jia-Bin Wang, Qi-Yue Chen, Long-Long Cao, Mi Lin, Ru-Hong Tu, and Chang-Ming Huang
57495-57504
Abstract  |  PDF  |  Full Text  |  How to cite

Efficacy and safety of a reduced calcineurin inhibitor dose combined with mycophenolate mofetil in liver transplant patients with chronic renal dysfunction

https://doi.org/10.18632/oncotarget.15490

Pusen Wang, Weitao Que, Hao Li, Lvnan Yan, Zhiren Fu, Qifa Ye, Guihua Chen, Kefeng Dou, Shichun Lu, Zhanyu Yang, Zhijun Zhu, Zhihai Peng, and Lin Zhong
57505-57515
Abstract  |  PDF  |  Full Text  |  How to cite

Preoperative monocytelymphocyte and neutrophillymphocyte but not plateletlymphocyte ratios are predictive of clinical outcomes in resected patients with nonmetastatic Siewert type II/III adenocarcinoma of esophagogastric junction: a prospective cohort study the AMONP corhort

https://doi.org/10.18632/oncotarget.15497

Jia-Wei Zhang, Lei Huang, and A-Man Xu
57516-57527
Abstract  |  PDF  |  Full Text  |  How to cite

Biomarker analysis of the phase 3 TORCH trial for first line erlotinib versus chemotherapy in advanced nonsmall cell lung cancer patients

https://doi.org/10.18632/oncotarget.15725

Lucia Kim, Mauro Saieg, Massimo Di Maio, Ciro Gallo, Charles Butts, Fortunato Ciardiello, Ronald Feld, Dengxiao Cheng, Vittorio Gebbia, Marco Angelo Burgio, Yasmin Alam, Simona Signoriello, Antonio Rossi, Natasha Leighl, Paolo Maione, Alessandro Morabito, Geoffrey Liu, Ming-Sound Tsao, Francesco Perrone, and Cesare Gridelli
57528-57536
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The application of IS6110baced loopmediated isothermal amplification LAMP in the early diagnosis of tuberculous meningitis

https://doi.org/10.18632/oncotarget.15734

Wen-Wen Sun, Qin Sun, Li-Ping Yan, and Qing Zhang
57537-57542
Abstract  |  PDF  |  Full Text  |  How to cite

Association of preoperative depressive and anxiety symptoms with fiveyear survival of glioma and meningioma patients: a prospective cohort study

https://doi.org/10.18632/oncotarget.15743

Adomas Bunevicius, Vytenis Pranas Deltuva, and Arimantas Tamasauskas
57543-57551
Abstract  |  PDF  |  Full Text  |  How to cite

Evaluation of intracavitary administration of curcumin for the treatment of sarcomatoid mesothelioma

https://doi.org/10.18632/oncotarget.15744

Daniel L. Pouliquen, Béatrice Nawrocki-Raby, Joëlle Nader, Stéphanie Blandin, Myriam Robard, Philippe Birembaut, and Marc Grégoire
57552-57573
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

TOP2A GGH and PECAM1 are associated with hematogenous lymph node and peritoneal recurrence in stage II/III gastric cancer patients enrolled in the ACTSGC study

https://doi.org/10.18632/oncotarget.15895

Masanori Terashima, Wataru Ichikawa, Atsushi Ochiai, Koji Kitada, Issei Kurahashi, Shinichi Sakuramoto, Hitoshi Katai, Takeshi Sano, Hiroshi Imamura, Mitsuru Sasako, and for the ACTS-GC Group
57574-57582
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Preoperative assessment of mitral valve abnormalities in left atrial myxoma patients using cardiac CT

https://doi.org/10.18632/oncotarget.16139

Jing Chen, Zhi-Gang Yang, En-Sen Ma, Qin Zhang, Xi Liu, and Ying-Kun Guo
57583-57593
Abstract  |  PDF  |  Full Text  |  How to cite

Risk of aortic aneurysm and dissection in patients with autosomaldominant polycystic kidney disease: a nationwide populationbased cohort study

https://doi.org/10.18632/oncotarget.16338

Pei-Hsun Sung, Yao-Hsu Yang, Hsin-Ju Chiang, John Y. Chiang, Chi-Jen Chen, Chien-Ting Liu, Cheuk-Man Yu, and Hon-Kan Yip
57594-57604
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Reviews

Biological effects and epidemiological consequences of arsenic exposure and reagents that can ameliorate arsenic damage in vivo

https://doi.org/10.18632/oncotarget.17745

Chinthalapally V. Rao, Sanya Pal, Altaf Mohammed, Mudassir Farooqui, Mark P. Doescher, Adam S. Asch, and Hiroshi Y. Yamada
57605-57621
Abstract  |  PDF  |  Full Text  |  How to cite

The fat and the bad: Mature adipocytes key actors in tumor progression and resistance

https://doi.org/10.18632/oncotarget.18038

Minh Ngoc Duong, Aline Geneste, Frederique Fallone, Xia Li, Charles Dumontet, and Catherine Muller
57622-57641
Abstract  |  PDF  |  Full Text  |  How to cite

Comparison among fertilitysparing therapies for well differentiated earlystage endometrial carcinoma and complex atypical hyperplasia

https://doi.org/10.18632/oncotarget.17588

Qing Zhang, Gonghua Qi, Margaux J. Kanis, Ruifen Dong, Baoxia Cui, Xingsheng Yang, and Beihua Kong
57642-57653
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Targeted therapies for gastric cancer: failures and hopes from clinical trials

https://doi.org/10.18632/oncotarget.14825

Maria Apicella, Simona Corso, and Silvia Giordano
57654-57669
Abstract  |  PDF  |  Full Text  |  How to cite

Treatments of traumatic neuropathic pain: a systematic review

https://doi.org/10.18632/oncotarget.16917

Chenglun Yao, Xijie Zhou, Bin Zhao, Chao Sun, Keshav Poonit, and Hede Yan
57670-57679
Abstract  |  PDF  |  Full Text  |  How to cite

Driver genes in nonsmall cell lung cancer: Characteristics detection methods and targeted therapies

https://doi.org/10.18632/oncotarget.17016

Qing-Ge Zhu, Shi-Ming Zhang, Xiao-Xiao Ding, Bing He, and Hu-Qin Zhang
57680-57692
Abstract  |  PDF  |  Full Text  |  How to cite
Special Collection ToC

Promising landscape for regulating macrophage polarization: epigenetic viewpoint

https://doi.org/10.18632/oncotarget.17027

Dexi Zhou, Kui Yang, Lu Chen, Wen Zhang, Zhenyu Xu, Jian Zuo, Hui Jiang, and Jiajie Luan
57693-57706
Abstract  |  PDF  |  Full Text  |  How to cite

The role of autophagy in hepatocellular carcinoma: friend or foe

https://doi.org/10.18632/oncotarget.17202

Lian Liu, Jia-Zhi Liao, Xing-Xing He, and Pei-Yuan Li
57707-57722
Abstract  |  PDF  |  Full Text  |  How to cite

Augmented expression of pololike kinase 1 indicates poor clinical outcome for breast patients: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.17301

Yunfeng Zhang, Zhibin Wu, Dapeng Liu, Meng Wang, Guodong Xiao, Peili Wang, Xin Sun, Hong Ren, Shou-Ching Tang, and Ning Du
57723-57732
Abstract  |  PDF  |  Full Text  |  How to cite

Targeting metabolism and AMPactivated kinase with metformin to sensitize nonsmall cell lung cancer NSCLC to cytotoxic therapy: translational biology and rationale for current clinical trials

https://doi.org/10.18632/oncotarget.17496

Michael Troncone, Stephanie M. Cargnelli, Linda A. Villani, Naghmeh Isfahanian, Lindsay A. Broadfield, Laura Zychla, Jim Wright, Gregory Pond, Gregory R. Steinberg, and Theodoros Tsakiridis
57733-57754
Abstract  |  PDF  |  Full Text  |  How to cite

The prognostic value of long noncoding RNAs in prostate cancer: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.17645

Weijie Ma, Xi Chen, Lu Ding, Jianhong Ma, Wei Jing, Tian Lan, Haseeb Sattar, Yongchang Wei, Fuling Zhou, and Yufeng Yuan
57755-57765
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Insights from animal models of bladder cancer: recent advances challenges and opportunities

https://doi.org/10.18632/oncotarget.17714

Bincy Anu John, and Neveen Said
57766-57781
Abstract  |  PDF  |  Full Text  |  How to cite

Vitamin K and its analogs: Potential avenues for prostate cancer management

https://doi.org/10.18632/oncotarget.17997

Subramanyam Dasari, Syed M. Ali, Guoxing Zheng, Aoshuang Chen, Venkata Satish Dontaraju, Maarten C. Bosland, Andre Kajdacsy-Balla, and Gnanasekar Munirathinam
57782-57799
Abstract  |  PDF  |  Full Text  |  How to cite

Formation function and exhaustion of notochordal cytoplasmic vacuoles within intervertebral disc: current understanding and speculation

https://doi.org/10.18632/oncotarget.18101

Feng Wang, Zeng-Xin Gao, Feng Cai, Arjun Sinkemani, Zhi-Yang Xie, Rui Shi, Ji-Nan Wei, and Xiao-Tao Wu
57800-57812
Abstract  |  PDF  |  Full Text  |  How to cite

The reverse Warburg effect is likely to be an Achilles’ heel of cancer that can be exploited for cancer therapy

https://doi.org/10.18632/oncotarget.18175

Yaojie Fu, Shanshan Liu, Shanghelin Yin, Weihong Niu, Wei Xiong, Ming Tan, Guiyuan Li, and Ming Zhou
57813-57825
Abstract  |  PDF  |  Full Text  |  How to cite

The efficacy of antiPD1/PDL1 therapy and its comparison with EGFRTKIs for advanced nonsmallcell lung cancer

https://doi.org/10.18632/oncotarget.18406

Zhixin Sheng, Xu Zhu, Yanhua Sun, and Yanxia Zhang
57826-57835
Abstract  |  PDF  |  Full Text  |  How to cite

Epigenetic regulation during the differentiation of stem cells to germ cells

https://doi.org/10.18632/oncotarget.18444

Yuan-Chao Sun, Yong-Yong Wang, Wei Ge, Shun-Feng Cheng, Paul W. Dyce, and Wei Shen
57836-57844
Abstract  |  PDF  |  Full Text  |  How to cite

Implementation and utilization of the molecular tumor board to guide precision medicine

https://doi.org/10.18632/oncotarget.18471

Shuko Harada, Rebecca Arend, Qian Dai, Jessica A. Levesque, Thomas S. Winokur, Rongjun Guo, Martin J. Heslin, Lisle Nabell, L. Burt Nabors, Nita A. Limdi, Kevin A. Roth, Edward E. Partridge, Gene P. Siegal, and Eddy S. Yang
57845-57854
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

p53 p63 and p73 in the wonderland of S cerevisiae

https://doi.org/10.18632/oncotarget.18506

Olivier Billant, Marc Blondel, and Cécile Voisset
57855-57869
Abstract  |  PDF  |  Full Text  |  How to cite

The PI3K/Akt pathway: a critical player in intervertebral disc degeneration

https://doi.org/10.18632/oncotarget.18628

Zhi-Hua Ouyang, Wen-Jun Wang, Yi-Guo Yan, Bin Wang, and Guo-Hua Lv
57870-57881
Abstract  |  PDF  |  Full Text  |  How to cite

Case Reports

Genomic analysis of exceptional responder to regorafenib in treatmentrefractory metastatic rectal cancer: a case report and review of the literature

https://doi.org/10.18632/oncotarget.18357

Krittiya Korphaisarn, Jonathan M. Loree, Van Nguyen, Ryanne Coulson, Vijaykumar Holla, Beate C. Litzenburger, Ken Chen, Gordon B. Mills, Dipen M. Maru, Funda Meric-Bernstan, Kenna R. Mills Shaw, and Scott Kopetz
57882-57888
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Pseudoprogression in microsatellite instabilityhigh colorectal cancer during treatment with combination T cell mediated immunotherapy: a case report and literature review

https://doi.org/10.18632/oncotarget.18361

Young Kwang Chae, Si Wang, Halla Nimeiri, Aparna Kalyan, and Francis J. Giles
57889-57897
Abstract  |  PDF  |  Full Text  |  How to cite

Dramatic response of CTNNB1 and VEGFR2 mutant temporal bone squamous cell carcinoma to bevacizumab in combination with pemetrexed

https://doi.org/10.18632/oncotarget.19649

Lai Wei, Lizhi Wang, Ziye Liu, Meiyi Wang, Weili Lu, Dewei Zhao, Bin Yang, Xuejun Kong, Yan Ding, and Zhiqiang Wang
57898-57904
Abstract  |  PDF  |  Full Text  |  How to cite

Corrections

Correction: A novel highly potent trivalent TGFβ receptor trap inhibits earlystage tumorigenesis and tumor cell invasion in murine Ptendeficient prostate glands

https://doi.org/10.18632/oncotarget.20370

Tai Qin, Lindsey Barron, Lu Xia, Haojie Huang, Maria M. Villarreal, John Zwaagstra, Cathy Collins, Junhua Yang, Christian Zwieb, Ravindra Kodali, Cynthia S. Hinck, Sun Kyung Kim, Robert L. Reddick, Chang Shu, Maureen D. O’Connor-McCourt, Andrew P. Hinck, and Lu-Zhe Sun
57905-57905
Correction  |  PDF  |  How to cite

Correction: Increased autophagy in fibroblastlike synoviocytes leads to immune enhancement potential in rheumatoid arthritis

https://doi.org/10.18632/oncotarget.20371

Ru Yang, Yingzi Zhang, Lin Wang, Ji Hu, Jian Wen, Leixi Xue, Mei Tang, Zhichun Liu, and Jinxiang Fu
57906-57906
Correction  |  PDF  |  How to cite

Research Papers

C1orf64 is a novel androgen receptor target gene and coregulator that interacts with 1433 protein in breast cancer

https://doi.org/10.18632/oncotarget.17826

Ali Naderi
57907-57933
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite


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