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Spatially- and temporally-controlled postnatal p53 knockdown cooperates with embryonic Schwann cell precursor Nf1 gene loss to promote malignant peripheral nerve sheath tumor formation. See Hirbe et al.
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Table of Contents
Editorial
Editorial: Chromosome
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| Understanding genome structural variations |
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https://doi.org/10.18632/oncotarget.6485
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| 7370-7371 |
Priority Research Papers
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| Antimetabolite TTL315 selectively kills glucosedeprived cancer cells and enhances responses to cytotoxic chemotherapy in preclinical models of cancer |
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https://doi.org/10.18632/oncotarget.7058
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| 7372-7380 |
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| A targeted genetic association study of epithelial ovarian cancer susceptibility |
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https://doi.org/10.18632/oncotarget.7121
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| 7381-7389 |
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| Inhibitors of histone deacetylase 1 reverse the immune evasion phenotype to enhance Tcell mediated lysis of prostate and breast carcinoma cells |
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https://doi.org/10.18632/oncotarget.7180
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| 7390-7402 |
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| Spatially and temporallycontrolled postnatal p53 knockdown cooperates with embryonic Schwann cell precursor Nf1 gene loss to promote malignant peripheral nerve sheath tumor formation |
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https://doi.org/10.18632/oncotarget.7232
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| 7403-7414 |
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| Systematic drug perturbations on cancer cells reveal diverse exit paths from proliferative state |
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https://doi.org/10.18632/oncotarget.7294
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| 7415-7425 |
Research Papers: Gerotarget (Focus on Aging)
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| Epigallocatechin3gallate induces oxidative phosphorylation by activating cytochrome c oxidase in human cultured neurons and astrocytes |
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https://doi.org/10.18632/oncotarget.6863
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| 7426-7440 |
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| Neuronal hemoglobin in mitochondria is reduced by forming a complex with αsynuclein in aging monkey brains |
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https://doi.org/10.18632/oncotarget.7046
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| 7441-7454 |
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| Identification of novel plasma glycosylationassociated markers of aging |
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https://doi.org/10.18632/oncotarget.7059
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| 7455-7468 |
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| Selective brain penetrable Nurr1 transactivator for treating Parkinson’s disease |
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https://doi.org/10.18632/oncotarget.7191
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| 7469-7479 |
Research Papers: Pathology
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| Epithelioid hemangioendotheliomas with TFE3 gene translocations are compossible with CAMTA1 gene rearrangements |
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https://doi.org/10.18632/oncotarget.7060
|
| 7480-7488 |
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| Thrombopoietin: a potential diagnostic indicator of immune thrombocytopenia in pregnancy |
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https://doi.org/10.18632/oncotarget.7106
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| 7489-7496 |
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| Modular transcriptional repertoire and MicroRNA target analyses characterize genomic dysregulation in the thymus of Down syndrome infants |
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https://doi.org/10.18632/oncotarget.7120
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| 7497-7533 |
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| Crosstalk between Ca2+ signaling and mitochondrial H2O2 is required for rotenone inhibition of mTOR signaling pathway leading to neuronal apoptosis |
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https://doi.org/10.18632/oncotarget.7183
|
| 7534-7549 |
Research Papers: Immunology
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| Novel CXCL13 transgenic mouse: inflammation drives pathogenic effect of CXCL13 in experimental myasthenia gravis |
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https://doi.org/10.18632/oncotarget.6885
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| 7550-7562 |
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| Successful expansion of functional and stable regulatory T cells for immunotherapy in liver transplantation |
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https://doi.org/10.18632/oncotarget.6927
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| 7563-7577 |
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| Targeting Tolllike receptor 4 prevents cobaltmediated inflammation |
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https://doi.org/10.18632/oncotarget.7105
|
| 7578-7585 |
|
| Dynamics of cytotoxic T cell subsets during immunotherapy predicts outcome in acute myeloid leukemia |
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https://doi.org/10.18632/oncotarget.7210
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| 7586-7596 |
Reviews
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| 90 Yibritumomab tiuxetan: a nearly forgotten opportunity |
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https://doi.org/10.18632/oncotarget.6531
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| 7597-7609 |
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| Targeting Notch to overcome radiation resistance |
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https://doi.org/10.18632/oncotarget.6714
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| 7610-7628 |
Clinical Reviews
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| Effectiveness and safety of poly ADPribose polymerase inhibitors in cancer therapy: A systematic review and metaanalysis |
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https://doi.org/10.18632/oncotarget.5367
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| 7629-7639 |
Research Papers
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| Proteomic discovery of MNT as a novel interacting partner of E3 ubiquitin ligase E6AP and a key mediator of myeloid differentiation |
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https://doi.org/10.18632/oncotarget.6156
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| 7640-7656 |
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| Role of CD44high/CD133high HCT116 cells in the tumorigenesis of colon cancer |
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https://doi.org/10.18632/oncotarget.7084
|
| 7657-7666 |
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| Sonic hedgehog inhibitors prevent colitisassociated cancer via orchestrated mechanisms of IL6/gp130 inhibition 15PGDH induction Bcl2 abrogation and tumorsphere inhibition |
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https://doi.org/10.18632/oncotarget.6765
|
| 7667-7682 |
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| IGFI induces upregulation of DDR1 collagen receptor in breast cancer cells by suppressing MIR199a5p through the PI3K/AKT pathway |
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https://doi.org/10.18632/oncotarget.6524
|
| 7683-7700 |
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| Loss of CtIP disturbs homologous recombination repair and sensitizes breast cancer cells to PARP inhibitors |
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https://doi.org/10.18632/oncotarget.6715
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| 7701-7714 |
|
| Valproic acid potentiates the anticancer activity of capecitabine in vitro and in vivo in breast cancer models via induction of thymidine phosphorylase expression |
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https://doi.org/10.18632/oncotarget.6802
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| 7715-7731 |
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| Control of glioma cell migration and invasiveness by GDF15 |
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https://doi.org/10.18632/oncotarget.6816
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| 7732-7746 |
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| HDAC3 mediates smokinginduced pancreatic cancer |
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https://doi.org/10.18632/oncotarget.6820
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| 7747-7760 |
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| Adenomatous polyposis coli genotypedependent tolllike receptor 4 activity in colon cancer |
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https://doi.org/10.18632/oncotarget.6844
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| 7761-7772 |
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| Analysis of risk and predictors of brain radiation necrosis after radiosurgery |
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https://doi.org/10.18632/oncotarget.6532
|
| 7773-7779 |
|
| Hepatitis B virus X protein binding to hepsin promotes C3 production by inducing IL6 secretion from hepatocytes |
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https://doi.org/10.18632/oncotarget.6846
|
| 7780-7800 |
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| PHLPP negatively regulates cell motility through inhibition of Akt activity and integrin expression in pancreatic cancer cells |
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https://doi.org/10.18632/oncotarget.6848
|
| 7801-7815 |
|
| Hypoxiainducible factor 1 upregulation of both VEGF and ANGPTL4 is required to promote the angiogenic phenotype in uveal melanoma |
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https://doi.org/10.18632/oncotarget.6868
|
| 7816-7828 |
|
| Deletions of multidrug resistance gene loci in breast cancer leads to the downregulation of its expression and predict tumor response to neoadjuvant chemotherapy |
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https://doi.org/10.18632/oncotarget.6953
|
| 7829-7841 |
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| Recruited mast cells in the tumor microenvironment enhance bladder cancer metastasis via modulation of ERβ/CCL2/CCR2 EMT/MMP9 signals |
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https://doi.org/10.18632/oncotarget.5467
|
| 7842-7855 |
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| GPR171 expression enhances proliferation and metastasis of lung cancer cells |
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https://doi.org/10.18632/oncotarget.6856
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| 7856-7865 |
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| Long lasting MDM2/Translocator protein modulator: a new strategy for irreversible apoptosis of human glioblastoma cells |
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https://doi.org/10.18632/oncotarget.6872
|
| 7866-7884 |
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| PTEN deficiency promotes macrophage infiltration and hypersensitivity of prostate cancer to IAP antagonist/radiation combination therapy |
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https://doi.org/10.18632/oncotarget.6955
|
| 7885-7898 |
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| Inhibition of NADPH oxidase 1 activity and blocking the binding of cytosolic and membranebound proteins by honokiol inhibit migratory potential of melanoma cells |
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https://doi.org/10.18632/oncotarget.6860
|
| 7899-7912 |
|
| The role of PDL1 in the radiation response and prognosis for esophageal squamous cell carcinoma related to IL6 and Tcell immunosuppression |
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https://doi.org/10.18632/oncotarget.6861
|
| 7913-7924 |
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| Dlx2 and glutaminase upregulate epithelialmesenchymal transition and glycolytic switch |
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https://doi.org/10.18632/oncotarget.6879
|
| 7925-7939 |
|
| The prognostic effects of tumor infiltrating regulatory T cells and myeloid derived suppressor cells assessed by multicolor flow cytometry in gastric cancer patients |
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https://doi.org/10.18632/oncotarget.6958
|
| 7940-7951 |
|
| Prognostic value of lymph node ratio in stage IIIC epithelial ovarian cancer with nodepositive in a SEER populationbased study |
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https://doi.org/10.18632/oncotarget.6911
|
| 7952-7959 |
|
| Effects of RAF inhibitors on PI3K/AKT signalling depend on mutational status of the RAS/RAF signalling axis |
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https://doi.org/10.18632/oncotarget.6959
|
| 7960-7969 |
|
| Aberrant NRP1 expression serves as predicator of metastatic endometrial and lung cancers |
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https://doi.org/10.18632/oncotarget.6699
|
| 7970-7978 |
|
| Inhibition of breast cancer cell motility with a noncyclooxygenase inhibitory derivative of sulindac by suppressing TGFβ/miR21 signaling |
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https://doi.org/10.18632/oncotarget.6888
|
| 7979-7992 |
|
| Patientderived xenograft PDX tumors increase growth rate with time |
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https://doi.org/10.18632/oncotarget.6919
|
| 7993-8005 |
|
| Gene copy number variations in the leukocyte genome of hepatocellular carcinoma patients with integrated hepatitis B virus DNA |
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https://doi.org/10.18632/oncotarget.6895
|
| 8006-8018 |
|
| ROS1 copy number alterations are frequent in nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.6921
|
| 8019-8028 |
|
| ZYG11A serves as an oncogene in nonsmall cell lung cancer and influences CCNE1 expression |
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https://doi.org/10.18632/oncotarget.6904
|
| 8029-8042 |
|
| Lentivirusmediated PLCγ1 gene shorthairpin RNA suppresses tumor growth and metastasis of human gastric adenocarcinoma |
|
https://doi.org/10.18632/oncotarget.6976
|
| 8043-8054 |
|
| Genetic alterations and their clinical implications in gastric cancer peritoneal carcinomatosis revealed by wholeexome sequencing of malignant ascites |
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https://doi.org/10.18632/oncotarget.6977
|
| 8055-8066 |
|
| Fractionation of a tumorinitiating UV dose introduces DNA damageretaining cells in hairless mouse skin and renders subsequent TPApromoted tumors nonregressing |
|
https://doi.org/10.18632/oncotarget.6932
|
| 8067-8077 |
|
| CTNNA3 is a tumor suppressor in hepatocellular carcinomas and is inhibited by miR425 |
|
https://doi.org/10.18632/oncotarget.6978
|
| 8078-8089 |
|
| Hernandezine a novel AMPK activator induces autophagic cell death in drugresistant cancers |
|
https://doi.org/10.18632/oncotarget.6980
|
| 8090-8104 |
|
| Hydroxyurea synergizes with valproic acid in wildtype p53 acute myeloid leukaemia |
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https://doi.org/10.18632/oncotarget.6991
|
| 8105-8118 |
|
| Genomic loss of EZH2 leads to epigenetic modifications and overexpression of the HOX gene clusters in myelodysplastic syndrome |
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https://doi.org/10.18632/oncotarget.6992
|
| 8119-8130 |
|
| Transcriptional profiling analysis and functional prediction of long noncoding RNAs in cancer |
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https://doi.org/10.18632/oncotarget.6993
|
| 8131-8142 |
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| Expression of aquaporin1 a water channel protein in cytoplasm is negatively correlated with prognosis of breast cancer patients |
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https://doi.org/10.18632/oncotarget.6994
|
| 8143-8154 |
|
| Multiple direct and indirect mechanisms drive estrogeninduced tumor growth in high grade serous ovarian cancers |
|
https://doi.org/10.18632/oncotarget.6943
|
| 8155-8171 |
|
| Identification of approved and investigational drugs that inhibit hypoxiainducible factor1 signaling |
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https://doi.org/10.18632/oncotarget.6995
|
| 8172-8183 |
|
| p38 MAPKinduced MDM2 degradation confers paclitaxel resistance through p53mediated regulation of EGFR in human lung cancer cells |
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https://doi.org/10.18632/oncotarget.6945
|
| 8184-8199 |
|
| LOX expression in primary nasopharyngeal carcinoma: correlation with prognostic parameters and outcome |
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https://doi.org/10.18632/oncotarget.6996
|
| 8200-8207 |
|
| A SNP in primiR10a is associated with recurrent spontaneous abortion in a HanChinese population |
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https://doi.org/10.18632/oncotarget.7002
|
| 8208-8222 |
|
| microRNA203 suppresses invasion and epithelialmesenchymal transition induction via targeting NUAK1 in head and neck cancer |
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https://doi.org/10.18632/oncotarget.6972
|
| 8223-8239 |
|
| TSGΔ1541054 splice variant increases TSG101 oncogenicity by inhibiting its E3ligasemediated proteasomal degradation |
|
https://doi.org/10.18632/oncotarget.6973
|
| 8240-8252 |
|
| Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma |
|
https://doi.org/10.18632/oncotarget.6982
|
| 8253-8267 |
|
| microRNAs regulate TAL1 expression in Tcell acute lymphoblastic leukemia |
|
https://doi.org/10.18632/oncotarget.6987
|
| 8268-8281 |
|
| Identification of an aptamer through whole cellSELEX for targeting high metastatic liver cancers |
|
https://doi.org/10.18632/oncotarget.6988
|
| 8282-8294 |
|
| A novel contribution of spvB to pathogenesis of Salmonella Typhimurium by inhibiting autophagy in host cells |
|
https://doi.org/10.18632/oncotarget.6989
|
| 8295-8309 |
|
| Multiple gene sequencing for risk assessment in patients with earlyonset or familial breast cancer |
|
https://doi.org/10.18632/oncotarget.7027
|
| 8310-8320 |
|
| Whole exome and targeted deep sequencing identify genomewide allelic loss and frequent SETDB1 mutations in malignant pleural mesotheliomas |
|
https://doi.org/10.18632/oncotarget.7032
|
| 8321-8331 |
|
| Assessment of cytology based molecular analysis to guide targeted therapy in advanced nonsmallcell lung cancer |
|
https://doi.org/10.18632/oncotarget.6671
|
| 8332-8340 |
|
| HsamiR326 targets CCND1 and inhibits nonsmall cell lung cancer development |
|
https://doi.org/10.18632/oncotarget.7071
|
| 8341-8359 |
|
| Toward targeted therapy in chemotherapyresistant pancreatic cancer with a smart triptolide nanomedicine |
|
https://doi.org/10.18632/oncotarget.7073
|
| 8360-8372 |
|
| KRAS mutation is a weak but valid predictor for poor prognosis and treatment outcomes in NSCLC: A metaanalysis of 41 studies |
|
https://doi.org/10.18632/oncotarget.7080
|
| 8373-8388 |
Clinical Research Papers
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| Serum chemokine CC motif ligand 2 level as a diagnostic predictive and prognostic biomarker for prostate cancer |
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https://doi.org/10.18632/oncotarget.6690
|
| 8389-8398 |
|
| NTRK1 fusions for the therapeutic intervention of Korean patients with colon cancer |
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https://doi.org/10.18632/oncotarget.6724
|
| 8399-8412 |
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| Positive intratumoral chemokine CC motif receptor 8 expression predicts high recurrence risk of postoperation clearcell renal cell carcinoma patients |
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https://doi.org/10.18632/oncotarget.6761
|
| 8413-8421 |
|
| Phase III study of cisplatin with pemtrexed or vinorelbine plus concurrent late course accelerated hyperfractionated radiotherapy in patients with unresectable stage III nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.6871
|
| 8422-8431 |
|
| The effect of perioperative probiotics treatment for colorectal cancer: shortterm outcomes of a randomized controlled trial |
|
https://doi.org/10.18632/oncotarget.7045
|
| 8432-8440 |
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