Vol 8, No 7

Allelic imbalance in human breast cancer

Uncovering the role of USP54 in cancer

The making of a killer (T cell)

The Tat-Aβ1-6A2V(D) peptide against AD synaptopathy

Role of VEGF-A in chronic pain

Oxidative stress in neurodegenerative disease: causation or association?

Functional sites for anesthetics in GABA_A receptors

Imaging of MSC transplantation in neuroscience

Dissecting stress with transcriptomics

Gadd45a deficiency accelerates BCR-ABL driven chronic myelogenous leukemia

Test anxiety and telomere length: Academic stress in adolescents may not cause rapid telomere erosion

Genome-wide copy number aberrations and HER2 and FGFR1 alterations in primary breast cancer by molecular inversion probe microarray

Meta-analysis of the actions of antithymocyte globulin in patients undergoing allogeneic hematopoietic cell transplantation

Gedunin inhibits pancreatic cancer by altering sonic hedgehog signaling pathway

Drug-dependent functionalization of wild-type and mutant p53 in cisplatin-resistant human ovarian tumor cells

Full preclinical validation of the ¹²³I-labeled anti-PSMA antibody fragment ScFvD2B for prostate cancer imaging

FLT3 activating mutations display differential sensitivity to multiple tyrosine kinase inhibitors

Modeling the phenotype of spinal muscular atrophy by the direct conversion of human fibroblasts to motor neurons

A neutralized human LMP1-IgG inhibits ENKTL growth by suppressing the JAK3/STAT3 signaling pathway

Combined inhibition of Wee1 and Chk1 gives synergistic DNA damage in S-phase due to distinct regulation of CDK activity and CDC45 loading

The role of miR-17-92 in the miRegulatory landscape of Ewing sarcoma

Preoperative serum levels of insulin-like growth factor-binding protein 2 predict prognosis of gastric cancer patients

UV-induced proteolysis of RNA polymerase II is mediated by VCP/p97 segregase and timely orchestration by Cockayne syndrome B protein

Preclinical efficacy of Sym004, novel anti-EGFR antibody mixture, in esophageal squamous cell carcinoma cell lines

Chromosome nondisjunction during bipolar mitoses of binucleated intermediates promote aneuploidy formation along with multipolar mitoses rather than chromosome loss in micronuclei induced by asbestos

Mcl-1 expression and JNK activation induces a threshold for apoptosis in Bcl-xL-overexpressing hematopoietic cells

Otub1 stabilizes MDMX and promotes its proapoptotic function at the mitochondria

Serum hepatitis B core antibody titer use in screening for significant fibrosis in treatment-naïve patients with chronic hepatitis B

miR-138-5p suppresses autophagy in pancreatic cancer by targeting SIRT1

Molecular differences between cerebral blood volume and vessel size in glioblastoma multiforme

Direct analysis of aberrant glycosylation on haptoglobin in patients with gastric cancer

Nuclear receptor retinoid-related orphan receptor alpha promotes apoptosis but is reduced in human gastric cancer

Non-malignant respiratory epithelial cells preferentially proliferate from resected non-small cell lung cancer specimens cultured under conditionally reprogrammed conditions

Oxidative stress-induced epigenetic changes associated with malignant transformation of human kidney epithelial cells

CD133 in brain tumor: the prognostic factor

Central spindle proteins and mitotic kinesins are direct transcriptional targets of MuvB, B-MYB and FOXM1 in breast cancer cell lines and are potential targets for therapy

Multidrug resistance transporter profile reveals MDR3 as a marker for stratification of blastemal Wilms tumour patients

Keap1/Nrf2 pathway in kidney cancer: frequent methylation of KEAP1 gene promoter in clear renal cell carcinoma

Easily detectable cytomorphological features to evaluate during ROSE for rapid lung cancer diagnosis: from cytology to histology

Combination of Arsenic trioxide and Everolimus (Rad001) synergistically induces both autophagy and apoptosis in prostate cancer cells

Synthetic high-density lipoproteins as targeted monotherapy for chronic lymphocytic leukemia

IL-6/STAT3/TWIST inhibition reverses ionizing radiation-induced EMT and radioresistance in esophageal squamous carcinoma

Activation of TRPM7 by naltriben enhances migration and invasion of glioblastoma cells

Identifying genetic hypomethylation and upregulation of toll-like receptors in Kawasaki disease

Endoscopic versus laparoscopic resection of gastric gastrointestinal stromal tumors: a multicenter study

MET receptor variant R970C favors calpain-dependent generation of a fragment promoting epithelial cell scattering

SIRPα-antibody fusion proteins stimulate phagocytosis and promote elimination of acute myeloid leukemia cells

Secretion modification region-derived peptide blocks exosome release and mediates cell cycle arrest in breast cancer cells

Aeroallergen Der p 2 promotes motility of human non-small cell lung cancer cells via toll-like receptor-mediated up-regulation of urokinase-type plasminogen activator and integrin/focal adhesion kinase signaling

LSD1 binds to HPV16 E7 and promotes the epithelial-mesenchymal transition in cervical cancer by demethylating histones at the Vimentin promoter

miR-874-3p is down-regulated in hepatocellular carcinoma and negatively regulates PIN1 expression

MiR-410 induces stemness by inhibiting Gsk3β but upregulating β-catenin in non-small cells lung cancer

The correlation of age with chemotherapy-induced ovarian function failure in breast cancer patients

Nomogram analysis and external validation to predict the risk of lymph node metastasis in gastric cancer

Fe₃O₄ nanoparticles and cryoablation enhance ice crystal formation to improve the efficiency of killing breast cancer cells

MicroRNA-17 is downregulated in esophageal adenocarcinoma cancer stem-like cells and promotes a radioresistant phenotype

Tumor cell migration is inhibited by a novel therapeutic strategy antagonizing the alpha-7 receptor

Chinese herb cinobufagin-reduced cancer pain is associated with increased peripheral opioids by invaded CD^3/4/8 lymphocytes

Repression of Fyn-related kinase in breast cancer cells is associated with promoter site-specific CpG methylation

Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing

Radiotherapy improves survival in early stage extranodal natural killer/T cell lymphoma patients receiving asparaginase-based chemotherapy

Overexpression of colorectal cancer oncogene CHRDL2 predicts a poor prognosis

Identification of a synonymous variant in TRIM59 gene for gastric cancer risk in a Chinese population

Characterization of RNA editome in primary and metastatic lung adenocarcinomas

A novel ZEB1/HAS2 positive feedback loop promotes EMT in breast cancer

B-cell lymphomas involving Waldeyer’s ring characterized by distinctive clinical and histopathological features: a comparison of pediatric to adult patients

Dexamethasone induces docetaxel and cisplatin resistance partially through up-regulating Krüppel-like factor 5 in triple-negative breast cancer

Anaplastic lymphoma kinase L1198F and G1201E mutations identified in anaplastic thyroid cancer patients are not ligand-independent

Leukocytosis and neutrophilia predict outcome in locally advanced esophageal cancer treated with definitive chemoradiation

Genomic expression differences between cutaneous cells from red hair color individuals and black hair color individuals based on bioinformatic analysis

Multi-level suppression of receptor-PI3K-mTORC1 by fatty acid synthase inhibitors is crucial for their efficacy against ovarian cancer cells

Asthma and the risk of lung cancer: a meta-analysis

Matrine alleviates lipopolysaccharide-induced intestinal inflammation and oxidative stress via CCR7 signal

The SDF-1/CXCR4 axis promotes recovery after spinal cord injury by mediating bone marrow-derived from mesenchymal stem cells

MicroRNA 603 acts as a tumor suppressor and inhibits triple-negative breast cancer tumorigenesis by targeting elongation factor 2 kinase

ZGDHu-1 promotes apoptosis of mantle cell lymphoma cells

A new semisynthetic cardenolide analog 3β-[2-(1-amantadine)- 1-on-ethylamine]-digitoxigenin (AMANTADIG) affects G2/M cell cycle arrest and miRNA expression profiles and enhances proapoptotic survivin-2B expression in renal cell carcinoma cell lines

Activating transcription factor 3 is crucial for antitumor activity and to strengthen the antiviral properties of Onconase

TLR-activated plasmacytoid dendritic cells inhibit breast cancer cell growth in vitro and in vivo

Yes-associated protein 1 promotes papillary thyroid cancer cell proliferation by activating the ERK/MAPK signaling pathway

Matrine derivative YF-18 inhibits lung cancer cell proliferation and migration through down-regulating Skp2

Evolutionary selected Tibetan variants of HIF pathway and risk of lung cancer

Establishment and characterization of hypomethylating agent-resistant cell lines, MOLM/AZA-1 and MOLM/DEC-5

Arg-Leu-Tyr-Glu tetrapeptide inhibits tumor progression by suppressing angiogenesis and vascular permeability via VEGF receptor-2 antagonism

The prognostic significance of postoperative neutrophil-to-lymphocyte ratio after radical prostatectomy for localized prostate cancer

GLUT-1 overexpression as an unfavorable prognostic biomarker in patients with colorectal cancer

Subconjunctival injection of antagomir-21 alleviates corneal neovascularization in a mouse model of alkali-burned cornea

Identification of microRNAs implicated in the late differentiation stages of normal B cells suggests a central role for miRNA targets ZEB1 and TP53

TMPRSS2-ERG fusion promotes prostate cancer metastases in bone

Mitochondrial deficiency impairs hypoxic induction of HIF-1 transcriptional activity and retards tumor growth

25-Hydroxycholesterol is involved in the pathogenesis of amyotrophic lateral sclerosis

Large-scale DNA methylation expression analysis across 12 solid cancers reveals hypermethylation in the calcium-signaling pathway

Clostridium difficile colonization in preoperative colorectal cancer patients

Antitumor and antimetastatic activities of a novel benzothiazole-2-thiol derivative in a murine model of breast cancer

High expression of miR-105-1 positively correlates with clinical prognosis of hepatocellular carcinoma by targeting oncogene NCOA1

LINE-1 hypomethylation status of circulating cell-free DNA in plasma as a biomarker for colorectal cancer

Exosomes as mediators of platinum resistance in ovarian cancer

PI3K/mTOR dual inhibitor BEZ235 and histone deacetylase inhibitor Trichostatin A synergistically exert anti-tumor activity in breast cancer

Eukaryotic elongation factor 2 is a prognostic marker and its kinase a potential therapeutic target in HCC

Comparison of the tumor cell secretome and patient sera for an accurate serum-based diagnosis of pancreatic ductal adenocarcinoma

LOXL4 knockdown enhances tumor growth and lung metastasis through collagen-dependent extracellular matrix changes in triple-negative breast cancer

Autocrine VEGF signaling promotes cell proliferation through a PLC-dependent pathway and modulates Apatinib treatment efficacy in gastric cancer

The regulator of calcineurin 1 (RCAN1) inhibits nuclear factor kappaB signaling pathway and suppresses human malignant glioma cells growth

Enhancement of the bioavailability of a novel anticancer compound (acetyltanshinone IIA) by encapsulation within mPEG-PLGA nanoparticles: a study of formulation optimization, toxicity, and pharmacokinetics

Clonal evolution in therapy-related neoplasms

Systemically identifying and prioritizing risk lncRNAs through integration of pan-cancer phenotype associations

Pax-5 is a potent regulator of E-cadherin and breast cancer malignant processes

Sulforaphane inhibits cancer stem-like cell properties and cisplatin resistance through miR-214-mediated downregulation of c-MYC in non-small cell lung cancer

Effect of Trp53 gene deficiency on brain injury after neonatal hypoxia-ischemia

Molecular dynamics simulation reveals how phosphorylation of tyrosine 26 of phosphoglycerate mutase 1 upregulates glycolysis and promotes tumor growth

Endovascular brachytherapy combined with portal vein stenting and transarterial chemoembolization improves overall survival of hepatocellular carcinoma patients with main portal vein tumor thrombus

Lysosomal acid phosphatase 2 is an unfavorable prognostic factor but is associated with better survival in stage II colorectal cancer patients receiving chemotherapy

DUSP1 inhibits cell proliferation, metastasis and invasion and angiogenesis in gallbladder cancer

Surgical debulking promotes recruitment of macrophages and triggers glioblastoma phagocytosis in combination with CD47 blocking immunotherapy

Human papillomavirus type 16 E6 suppresses microRNA-23b expression in human cervical cancer cells through DNA methylation of the host gene C9orf3

NMI promotes hepatocellular carcinoma progression via BDKRB2 and MAPK/ERK pathway

Elevated fibrous sheath interacting protein 1 levels are associated with poor prognosis in non-small cell lung cancer patients

ABL2 suppresses FLT3-ITD-induced cell proliferation through negative regulation of AKT signaling

A nomogram to predict lymph node metastasis in patients with early gastric cancer

Cordycepin induces apoptosis by caveolin-1-mediated JNK regulation of Foxo3a in human lung adenocarcinoma

Low rate of positive margins and re-excision after partial mastectomy in highly selected breast cancer patients: A Chinese single-institution experience

Identification of aurintricarboxylic acid as a selective inhibitor of the TWEAK-Fn14 signaling pathway in glioblastoma cells

⁶⁸Ga-PSMA-11 PET/CT for prostate cancer staging and risk stratification in Chinese patients

Piwil2-transfected human fibroblasts are cancer stem cell-like and genetically unstable

A new model of multi-visceral and bone metastatic prostate cancer with perivascular niche targeting by a novel endothelial specific adenoviral vector

Association of RAB5 overexpression in pancreatic cancer with cancer progression and poor prognosis via E-cadherin suppression

Ellagic acid inhibits the proliferation of human pancreatic carcinoma PANC-1 cells in vitro and in vivo

RXRα ligand Z-10 induces PML-RARα cleavage and APL cell apoptosis through disrupting PML-RARα/RXRα complex in a cAMP-independent manner

Novel circulating lipid measurements for current dyslipidemias in non-treated patients undergoing coronary angiography: PCSK9, apoC3 and sdLDL-C

Better transplant outcome with pre-transplant marrow response after hypomethylating treatment in higher-risk MDS with excess blasts

Preoperative peripheral plasma fibrinogen level is an independent prognostic marker in penile cancer

Aging, obesity, and post-therapy cognitive recovery in breast cancer survivors

Bevacizumab in ovarian cancer: A critical review of phase III studies

What influences preneoplastic colorectal lesion recurrence?

Developmental therapeutics for inflammatory breast cancer: Biology and translational directions

MicroRNAs as regulators and mediators of forkhead box transcription factors function in human cancers

The role of prostate tumor overexpressed 1 in cancer progression

The crosstalk between lncRNA and microRNA in cancer metastasis: orchestrating the epithelial-mesenchymal plasticity

Epigenetic therapy in urologic cancers: an update on clinical trials

Guide to detecting epidermal growth factor receptor (EGFR) mutations in ctDNA of patients with advanced non-small-cell lung cancer

LncRNAs: the bridge linking RNA and colorectal cancer