|
| Blocking the survival of the nastiest by HSP90 inhibition |
|
https://doi.org/10.18632/oncotarget.6971
Paul Workman, Paul A. Clarke, and Bissan Al-Lazikani
|
| 3658-3661 |
|
| A multiplexed markerbased algorithm for diagnosis of carcinoma of unknown primary using circulating tumor cells |
|
https://doi.org/10.18632/oncotarget.6657
Elizabeth M. Matthew, Lanlan Zhou, Zhaohai Yang, David T. Dicker, Sheldon L. Holder, Bora Lim, Ramdane Harouaka, Si-Yang Zheng, Joseph J. Drabick, Nicholas E. Lamparella, Cristina I. Truica, and Wafik S. El-Deiry
|
| 3662-3676 |
|
| SHIP represses lung inflammation and inhibits mammary tumor metastasis in BALB/c mice |
|
https://doi.org/10.18632/oncotarget.6611
Melisa J. Hamilton, Elizabeth C. Halvorsen, Nancy E. LePard, Momir Bosiljcic, Victor W. Ho, Vivian Lam, Judit Banáth, Kevin L. Bennewith, and Gerald Krystal
|
| 3677-3691 |
|
| Core level regulatory network of osteoblast as molecular mechanism for osteoporosis and treatment |
|
https://doi.org/10.18632/oncotarget.6923
Ruoshi Yuan, Shengfei Ma, Xiaomei Zhu, Jun Li, Yuhong Liang, Tao Liu, Yanxia Zhu, Bingbing Zhang, Shuang Tan, Huajie Guo, Shuguang Guan, Ping Ao, and Guangqian Zhou
|
| 3692-3701 |
|
| Alphafetoprotein still is a valuable diagnostic and prognosis predicting biomarker in hepatitis B virus infectionrelated hepatocellular carcinoma |
|
https://doi.org/10.18632/oncotarget.6913
Mingjie Yao, Jingmin Zhao, and Fengmin Lu
|
| 3702-3708 |
|
| Cooperative TRAIL production mediates IFNα/Smac mimeticinduced cell death in TNFαresistant solid cancer cells |
|
https://doi.org/10.18632/oncotarget.6915
Stefanie Roesler, Ines Eckhardt, Sebastian Wolf, and Simone Fulda
|
| 3709-3725 |
|
| DNA demethylation caused by 5Aza2’deoxycytidine induces mitotic alterations and aneuploidy |
|
https://doi.org/10.18632/oncotarget.6897
Giuseppe Costa, Viviana Barra, Laura Lentini, Danilo Cilluffo, and Aldo Di Leonardo
|
| 3726-3739 |
|
| Leptomeningeal metastasis in breast cancer – a systematic review |
|
https://doi.org/10.18632/oncotarget.5911
Brian J. Scott, Nancy A. Oberheim-Bush, and Santosh Kesari
|
| 3740-3747 |
|
| The role of the oncofetal H19 lncRNA in tumor metastasis: orchestrating the EMTMET decision |
|
https://doi.org/10.18632/oncotarget.6387
Imad J. Matouk, David Halle, Eli Raveh, Michal Gilon, Vladimir Sorin, and Avraham Hochberg
|
| 3748-3765 |
|
| DAB2IP in cancer |
|
https://doi.org/10.18632/oncotarget.6501
Liang Liu, Cong Xu, Jer-Tsong Hsieh, Jianping Gong, and Daxing Xie
|
| 3766-3776 |
|
| Leukemia inhibitory factor promotes EMT through STAT3dependent miR21 induction |
|
https://doi.org/10.18632/oncotarget.6756
Xuetian Yue, Yuhan Zhao, Cen Zhang, Jun Li, Zhen Liu, Juan Liu, and Wenwei Hu
|
| 3777-3790 |
|
| Overexpressed CISD2 has prognostic value in human gastric cancer and promotes gastric cancer cell proliferation and tumorigenesis via AKT signaling pathway |
|
https://doi.org/10.18632/oncotarget.6302
Lan Wang, Fei Ouyang, Xiaobo Liu, Shu Wu, Hong-mei Wu, Yuandong Xu, Bin Wang, Jinrong Zhu, Xuehu Xu, and Liang Zhang
|
| 3791-3805 |
|
| CD147 and downstream ADAMTSs promote the tumorigenicity of Kaposi’s sarcomaassociated herpesvirus infected endothelial cells |
|
https://doi.org/10.18632/oncotarget.6584
Lu Dai, Jimena Trillo-Tinoco, Yihan Chen, Karlie Bonstaff, Luis Del Valle, Chris Parsons, Augusto C. Ochoa, Jovanny Zabaleta, Bryan P. Toole, and Zhiqiang Qin
|
| 3806-3818 |
|
| The pentacyclic triterpenoid plectranthoic acid a novel activator of AMPK induces apoptotic death in prostate cancer cells |
|
https://doi.org/10.18632/oncotarget.6625
Nosheen Akhtar, Deeba N. Syed, Mohammad Imran Khan, Vaqar M. Adhami, Bushra Mirza, and Hasan Mukhtar
|
| 3819-3831 |
|
| Carnitine palmitoyltransferase 1A functions to repress FoxO transcription factors to allow cell cycle progression in ovarian cancer |
|
https://doi.org/10.18632/oncotarget.6757
Huanjie Shao, Esraa M. Mohamed, Guoyan G. Xu, Michael Waters, Kai Jing, Yibao Ma, Yan Zhang, Sarah Spiegel, Michael O. Idowu, and Xianjun Fang
|
| 3832-3846 |
|
| High efficacy of third generation EGFR inhibitor AZD9291 in a leptomeningeal carcinomatosis model with EGFRmutant lung cancer cells |
|
https://doi.org/10.18632/oncotarget.6758
Shigeki Nanjo, Hiromichi Ebi, Sachiko Arai, Shinji Takeuchi, Tadaaki Yamada, Satsuki Mochizuki, Yasunori Okada, Mitsutoshi Nakada, Takashi Murakami, and Seiji Yano
|
| 3847-3856 |
|
| Signature miRNAs in colorectal cancers were revealed using a bias reduction small RNA deep sequencing protocol |
|
https://doi.org/10.18632/oncotarget.6460
Guihua Sun, Ya-Wen Cheng, Lily Lai, Tsui-Chin Huang, Jinhui Wang, Xiwei Wu, Yafan Wang, Yasheng Huang, Jinghan Wang, Keqiang Zhang, Shuya Hu, Ji-Rui Yang, and Yun Yen
|
| 3857-3872 |
|
| Identification of H7 as a novel peroxiredoxin I inhibitor to induce differentiation of leukemia cells |
|
https://doi.org/10.18632/oncotarget.6763
Wei Wei, Chunmin Ma, Yang Cao, Li Yang, Zhimin Huang, Dongjun Qin, Yingyi Chen, Chuanxu Liu, Li Xia, Tongdan Wang, Hu Lei, Yun Yu, Min Huang, Yin Tong, Hanzhang Xu, Fenghou Gao, Jian Zhang, and Ying-Li Wu
|
| 3873-3883 |
|
| Overexpression of wildtype EGFR is tumorigenic and denotes a therapeutic target in nonsmall cell lung cancer |
|
https://doi.org/10.18632/oncotarget.6461
Naiqing Xu, Wenfeng Fang, Libing Mu, Yanna Tang, Lei Gao, Shengxiang Ren, Dengfeng Cao, Lixin Zhou, Aiqun Zhang, Deruo Liu, Caicun Zhou, Kwok-Kin Wong, Lei Yu, Li Zhang, and Liang Chen
|
| 3884-3896 |
|
| Heterogeneity and chronology of 6q15 deletion and ERGfusion in prostate cancer |
|
https://doi.org/10.18632/oncotarget.6597
Martina Kluth, David Meyer, Antje Krohn, Fabian Freudenthaler, Melanie Bauer, Georg Salomon, Hans Heinzer, Uwe Michl, Stefan Steurer, Ronald Simon, Guido Sauter, Thorsten Schlomm, and Sarah Minner
|
| 3897-3904 |
|
| Genetic deletion of osteopontin in TRAMP mice skews prostate carcinogenesis from adenocarcinoma to aggressive humanlike neuroendocrine cancers |
|
https://doi.org/10.18632/oncotarget.6678
Giorgio Mauri, Elena Jachetti, Barbara Comuzzi, Matteo Dugo, Ivano Arioli, Silvia Miotti, Sabina Sangaletti, Emma Di Carlo, Claudio Tripodo, and Mario P. Colombo
|
| 3905-3920 |
|
| Upregulation of REG3A in colorectal cancer cells confers proliferation and correlates with colorectal cancer risk |
|
https://doi.org/10.18632/oncotarget.6473
Ying Ye, Ling Xiao, Su-Juan Wang, Wei Yue, Qiao-Shan Yin, Meng-Yao Sun, Wei Xia, Zhi-Yi Shao, and Hong Zhang
|
| 3921-3933 |
|
| Targeting a novel domain in podoplanin for inhibiting plateletmediated tumor metastasis |
|
https://doi.org/10.18632/oncotarget.6598
Takaya Sekiguchi, Ai Takemoto, Satoshi Takagi, Kazuki Takatori, Shigeo Sato, Miho Takami, and Naoya Fujita
|
| 3934-3946 |
|
| Primary crossresistance to BRAFV600E MEK1/2 and PI3K/mTORspecific inhibitors in BRAFmutant melanoma cells counteracted by dual pathway blockade |
|
https://doi.org/10.18632/oncotarget.6600
Ilaria Penna, Alessandra Molla, Giulia Grazia, Loredana Cleris, Gabriella Nicolini, Federica Perrone, Benedetta Picciani, Michele Del Vecchio, Filippo de Braud, Roberta Mortarini, and Andrea Anichini
|
| 3947-3965 |
|
| Reduced expression of SET7/9 a histone monomethyltransferase is associated with gastric cancer progression |
|
https://doi.org/10.18632/oncotarget.6681
Yoshimitsu Akiyama, Yuki Koda, Sun-ju Byeon, Shu Shimada, Taketo Nishikawaji, Ayuna Sakamoto, Yingxuan Chen, Kazuyuki Kojima, Tatsuyuki Kawano, Yoshinobu Eishi, Dajun Deng, Woo Ho Kim, Wei-Guo Zhu, Yasuhito Yuasa, and Shinji Tanaka
|
| 3966-3983 |
|
| Simultaneous gene silencing of KRAS and antiapoptotic genes as a multitarget therapy |
|
https://doi.org/10.18632/oncotarget.6766
Kristin Werner, Franziska Lademann, May-Linn Thepkaysone, Beatrix Jahnke, Daniela E. Aust, Christoph Kahlert, Georg Weber, Jürgen Weitz, Robert Grützmann, and Christian Pilarsky
|
| 3984-3992 |
|
| Exosomes from bulk and stem cells from human prostate cancer have a differential microRNA content that contributes cooperatively over local and premetastatic niche |
|
https://doi.org/10.18632/oncotarget.6540
Catherine A. Sánchez, Eliana I. Andahur, Rodrigo Valenzuela, Enrique A. Castellón, Juan A. Fullá, Christian G. Ramos, and Juan C. Triviño
|
| 3993-4008 |
|
| miR30a inhibits endothelin A receptor and chemoresistance in ovarian carcinoma |
|
https://doi.org/10.18632/oncotarget.6546
Rosanna Sestito, Roberta Cianfrocca, Laura Rosanò, Piera Tocci, Elisa Semprucci, Valeriana Di Castro, Valentina Caprara, Gabriella Ferrandina, Andrea Sacconi, Giovanni Blandino, and Anna Bagnato
|
| 4009-4023 |
|
| Identification of the BRAF V600E mutation in gastroenteropancreatic neuroendocrine tumors |
|
https://doi.org/10.18632/oncotarget.6602
Charny Park, Sang Yun Ha, Seung Tae Kim, Hee Cheol Kim, Jin Seok Heo, Young Suk Park, Gregory Lauwers, Jeeyun Lee, and Kyoung-Mee Kim
|
| 4024-4035 |
|
| Periostin in tumor microenvironment is associated with poor prognosis and platinum resistance in epithelial ovarian carcinoma |
|
https://doi.org/10.18632/oncotarget.6700
Pi-Lin Sung, Yi-Hua Jan, Shih-Chieh Lin, Chao-Cheng Huang, Hao Lin, Kuo-Chang Wen, Kuan-Chong Chao, Chiung-Ru Lai, Peng-Hui Wang, Chi-Mu Chuang, Hua-Hsi Wu, Nae-Fang Twu, Ming-Shyen Yen, Michael Hsiao, and Chi-Ying F. Huang
|
| 4036-4047 |
|
| Enhanced expression of LINE1encoded ORF2 protein in early stages of colon and prostate transformation |
|
https://doi.org/10.18632/oncotarget.6767
Chiara De Luca, Fiorella Guadagni, Paola Sinibaldi-Vallebona, Steno Sentinelli, Michele Gallucci, Andreas Hoffmann, Gerald G. Schumann, Corrado Spadafora, and Ilaria Sciamanna
|
| 4048-4061 |
|
| Inhibiting the anaphase promoting complex/cyclosome induces a metaphase arrest and cell death in multiple myeloma cells |
|
https://doi.org/10.18632/oncotarget.6768
Susanne Lub, Anke Maes, Ken Maes, Kim De Veirman, Elke De Bruyne, Eline Menu, Karel Fostier, Alboukadel Kassambara, Jérôme Moreaux, Dirk Hose, Xavier Leleu, Randall W. King, Karin Vanderkerken, and Els Van Valckenborgh
|
| 4062-4076 |
|
| Liposome armed with herpes virusderived gH625 peptide to overcome doxorubicin resistance in lung adenocarcinoma cell lines |
|
https://doi.org/10.18632/oncotarget.6013
Emiliana Perillo, Stefania Porto, Annarita Falanga, Silvia Zappavigna, Paola Stiuso, Virginia Tirino, Vincenzo Desiderio, Gianpaolo Papaccio, Massimiliano Galdiero, Antonio Giordano, Stefania Galdiero, and Michele Caraglia
|
| 4077-4092 |
|
| Significant blockade of multiple receptor tyrosine kinases by MGCD516 Sitravatinib a novel small molecule inhibitor shows potent antitumor activity in preclinical models of sarcoma |
|
https://doi.org/10.18632/oncotarget.6547
Parag P. Patwardhan, Kathryn S. Ivy, Elgilda Musi, Elisa de Stanchina, and Gary K. Schwartz
|
| 4093-4109 |
|
| Loss of Ecadherin disrupts ovarian epithelial inclusion cyst formation and collective cell movement in ovarian cancer cells |
|
https://doi.org/10.18632/oncotarget.6588
Pui-Wah Choi, Junzheng Yang, Shu-Kay Ng, Colleen Feltmate, Michael G. Muto, Kathleen Hasselblatt, Kyle Lafferty-Whyte, Lellean JeBailey, Laura MacConaill, William R. Welch, Wing-Ping Fong, Ross S. Berkowitz, and Shu-Wing Ng
|
| 4110-4121 |
|
| Autophagy is involved in TGFβ1induced protective mechanisms and formation of cancerassociated fibroblasts phenotype in tumor microenvironment |
|
https://doi.org/10.18632/oncotarget.6702
Fang-Lan Liu, En-Pan Mo, Liu Yang, Jun Du, Hong-Sheng Wang, Huan Zhang, Hiroshi Kurihara, Jun Xu, and Shao-Hui Cai
|
| 4122-4141 |
|
| Combination therapy of RY104 with the γsecretase inhibitor DAPT shows promise in treating HER2amplified breast cancer |
|
https://doi.org/10.18632/oncotarget.6769
Feng Su, Shilin Zhu, Jinlan Ruan, Yagmur Muftuoglu, Longbo Zhang, and Qianying Yuan
|
| 4142-4154 |
|
| Lack of survival advantage with autologous stemcell transplantation in highrisk neuroblastoma consolidated by antiGD2 immunotherapy and isotretinoin |
|
https://doi.org/10.18632/oncotarget.6393
Brian H. Kushner, Irina Ostrovnaya, Irene Y. Cheung, Deborah Kuk, Shakeel Modak, Kim Kramer, Stephen S. Roberts, Ellen M. Basu, Karima Yataghene, and Nai-Kong V. Cheung
|
| 4155-4166 |
|
| Sphingosine kinase 1 is required for TGFβ mediated fibroblastto myofibroblast differentiation in ovarian cancer |
|
https://doi.org/10.18632/oncotarget.6703
Jessica A. Beach, Paul-Joseph P. Aspuria, Dong-Joo Cheon, Kate Lawrenson, Hasmik Agadjanian, Christine S. Walsh, Beth Y. Karlan, and Sandra Orsulic
|
| 4167-4182 |
|
| The prognostic role of desmoplastic stroma in pancreatic ductal adenocarcinoma |
|
https://doi.org/10.18632/oncotarget.6770
Lai Mun Wang, Michael A. Silva, Zenobia D’Costa, Robin Bockelmann, Zahir Soonawalla, Stanley Liu, Eric O’Neill, Somnath Mukherjee, W. Gillies McKenna, Ruth Muschel, and Emmanouil Fokas
|
| 4183-4194 |
|
| Epigenetic modification of TLR4 promotes activation of NFκB by regulating methylCpGbinding domain protein 2 and Sp1 in gastric cancer |
|
https://doi.org/10.18632/oncotarget.6549
Tae Woo Kim, Seon-Jin Lee, Byung Moo Oh, Heesoo Lee, Tae Gi Uhm, Jeong-Ki Min, Young-Jun Park, Suk Ran Yoon, Bo-Yeon Kim, Jong Wan Kim, Yong-Kyung Choe, and Hee Gu Lee
|
| 4195-4209 |
|
| Clinical implication of voltagedependent anion channel 1 in uterine cervical cancer and its action on cervical cancer cells |
|
https://doi.org/10.18632/oncotarget.6704
Chih-Hsien Wu, Yu-Wen Lin, Tzu-Fan Wu, Jiunn-Liang Ko, and Po-Hui Wang
|
| 4210-4225 |
|
| Overexpressed EDIL3 predicts poor prognosis and promotes anchorageindependent tumor growth in human pancreatic cancer |
|
https://doi.org/10.18632/oncotarget.6772
Shu-Heng Jiang, Yang Wang, Jian-Yu Yang, Jun Li, Ming-Xuan Feng, Ya-Hui Wang, Xiao-Mei Yang, Ping He, Guang-Ang Tian, Xiao-Xin Zhang, Qing Li, Xiao-Yan Cao, Yan-Miao Huo, Min-Wei Yang, Xue-Liang Fu, Jiao Li, De-Jun Liu, Miao Dai, Shan-Yun Wen, Jian-Ren Gu, Jie Hong, Rong Hua, Zhi-Gang Zhang, and Yong-Wei Sun
|
| 4226-4240 |
|
| Recurrent AKT mutations in human cancers: functional consequences and effects on drug sensitivity |
|
https://doi.org/10.18632/oncotarget.6648
Kyung H. Yi, and Josh Lauring
|
| 4241-4251 |
|
| Upregulation of flotillin1 promotes invasion and metastasis by activating TGFβ signaling in nasopharyngeal carcinoma |
|
https://doi.org/10.18632/oncotarget.6483
Sumei Cao, Yanmei Cui, Huiming Xiao, Miaoqing Mai, Chanjuan Wang, Shanghang Xie, Jing Yang, Shu Wu, Jun Li, Libing Song, Xiang Guo, and Chuyong Lin
|
| 4252-4264 |
|
| Metformin increases antitumor activity of MEK inhibitors through GLI1 downregulation in LKB1 positive human NSCLC cancer cells |
|
https://doi.org/10.18632/oncotarget.6559
Carminia Maria Della Corte, Vincenza Ciaramella, Concetta Di Mauro, Maria Domenica Castellone, Federica Papaccio, Morena Fasano, Ferdinando Carlo Sasso, Erika Martinelli, Teresa Troiani, Ferdinando De Vita, Michele Orditura, Roberto Bianco, Fortunato Ciardiello, and Floriana Morgillo
|
| 4265-4278 |
|
| RASSF10 is an epigenetically inactivated tumor suppressor and independent prognostic factor in hepatocellular carcinoma |
|
https://doi.org/10.18632/oncotarget.6654
Fei Wang, Ying Feng, Peng Li, Kun Wang, Liang Feng, Yi-Fei Liu, Hua Huang, Yi-Bing Guo, Qin-Sheng Mao, and Wan-Jiang Xue
|
| 4279-4297 |
|
| Identification of ovarian cancer subtypespecific network modules and candidate drivers through an integrative genomics approach |
|
https://doi.org/10.18632/oncotarget.6774
Di Zhang, Peng Chen, Chun-Hou Zheng, and Junfeng Xia
|
| 4298-4309 |
|
| CCL3 promotes angiogenesis by dysregulation of miR374b/ VEGFA axis in human osteosarcoma cells |
|
https://doi.org/10.18632/oncotarget.6708
Yuan-Ya Liao, Hsiao-Chi Tsai, Pei-Yu Chou, Shih-Wei Wang, Hsien-Te Chen, Yu-Min Lin, I-Ping Chiang, Tzu-Ming Chang, Shao-Keh Hsu, Ming-Chih Chou, Chih-Hsin Tang, and Yi-Chin Fong
|
| 4310-4325 |
|
| Reactivation of wildtype and mutant p53 by tryptophanolderived oxazoloisoindolinone SLMP531 a novel anticancer smallmolecule |
|
https://doi.org/10.18632/oncotarget.6775
Joana Soares, Liliana Raimundo, Nuno A.L. Pereira, Ângelo Monteiro, Sara Gomes, Cláudia Bessa, Clara Pereira, Glória Queiroz, Alessandra Bisio, João Fernandes, Célia Gomes, Flávio Reis, Jorge Gonçalves, Alberto Inga, Maria M.M. Santos, and LucÃlia Saraiva
|
| 4326-4343 |
|
| WWOX modulates the ATRmediated DNA damage checkpoint response |
|
https://doi.org/10.18632/oncotarget.6571
Mohammad Abu-Odeh, Nyla A. Hereema, and Rami I. Aqeilan
|
| 4344-4355 |
|
| Niacin alleviates TRAILmediated colon cancer cell death via autophagy flux activation |
|
https://doi.org/10.18632/oncotarget.5374
Sung-Wook Kim, Ju-Hee Lee, Ji-Hong Moon, Uddin M.D. Nazim, You-Jin Lee, Jae-Won Seol, Jin Hur, Seong-Kug Eo, John-Hwa Lee, and Sang-Youel Park
|
| 4356-4368 |
|
| Adenovirusmediated delivery of herpes simplex virus thymidine kinase administration improves outcome of recurrent highgrade glioma |
|
https://doi.org/10.18632/oncotarget.6737
Nan Ji, Danhui Weng, Cang Liu, Zheng Gu, Shizhang Chen, Ying Guo, Zhong Fan, Xiao Wang, Jianfei Chen, Yanyan Zhao, Jianfeng Zhou, Jisheng Wang, Ding Ma, and Ning Li
|
| 4369-4378 |
|
| Effect of pravastatin on the survival of patients with advanced gastric cancer |
|
https://doi.org/10.18632/oncotarget.6777
Luis Bujanda, Araceli RodrÃguez-González, Cristina Sarasqueta, Emma Eizaguirre, Elizabeth Hijona, José J.G. MarÃn, MarÃa J. Perugorria, Jesús M. Banales, and Angel Cosme
|
| 4379-4384 |
|
| Liver irradiation causes distal bystander effects in the rat brain and affects animal behaviour |
|
https://doi.org/10.18632/oncotarget.6596
Anna Kovalchuk, Richelle Mychasiuk, Arif Muhammad, Shakhawat Hossain, Slava Ilnytskyy, Abhijit Ghose, Charles Kirkby, Esmaeel Ghasroddashti, Olga Kovalchuk, and Bryan Kolb
|
| 4385-4398 |
|
| Sildenafil Viagra sensitizes prostate cancer cells to doxorubicinmediated apoptosis through CD95 |
|
https://doi.org/10.18632/oncotarget.6749
Anindita Das, David Durrant, Clint Mitchell, Paul Dent, Surinder K. Batra, and Rakesh C. Kukreja
|
| 4399-4413 |
|
| GNA13 as a prognostic factor and mediator of gastric cancer progression |
|
https://doi.org/10.18632/oncotarget.6780
Jia-Xing Zhang, Miao Yun, Yi Xu, Jie-Wei Chen, Hui-Wen Weng, Zou-San Zheng, Cui Chen, Dan Xie, and Sheng Ye
|
| 4414-4427 |
|
| Overcoming melanoma resistance to vemurafenib by targeting CCL2induced miR34a miR100 and miR125b |
|
https://doi.org/10.18632/oncotarget.6599
Elisabetta Vergani, Lorenza Di Guardo, Matteo Dugo, Sara Rigoletto, Gabrina Tragni, Roberta Ruggeri, Federica Perrone, Elena Tamborini, Annunziata Gloghini, Flavio Arienti, Barbara Vergani, Paola Deho, Loris De Cecco, Viviana Vallacchi, Paola Frati, Eriomina Shahaj, Antonello Villa, Mario Santinami, Filippo De Braud, Licia Rivoltini, and Monica Rodolfo
|
| 4428-4441 |
|
| p130Cas scaffold protein regulates ErbB2 stability by altering breast cancer cell sensitivity to autophagy |
|
https://doi.org/10.18632/oncotarget.6710
Brigitte Bisaro, Marianna Sciortino, Shana Colombo, Maria Pilar Camacho Leal, Andrea Costamagna, Isabella Castellano, Filippo Montemurro, Valentina Rossi, Giorgio Valabrega, Emilia Turco, Paola Defilippi, and Sara Cabodi
|
| 4442-4453 |
|
| Induction of MAPK and ROSdependent autophagy and apoptosis in gastric carcinoma by combination of romidepsin and bortezomib |
|
https://doi.org/10.18632/oncotarget.6601
Kwai Fung Hui, Po Ling Yeung, and Alan K.S. Chiang
|
| 4454-4467 |
|
| Snail1 is required for the maintenance of the pancreatic acinar phenotype |
|
https://doi.org/10.18632/oncotarget.6785
Jordina Loubat-Casanovas, Raúl Peña, Núria Gonzà lez, Lorena Alba-Castellón, Santi Rosell, Clara FrancÃ, Pilar Navarro, and Antonio GarcÃa de Herreros
|
| 4468-4482 |
|
| Diabetes mellitus and the risk of glioma: a metaanalysis |
|
https://doi.org/10.18632/oncotarget.6605
Luqian Zhao, Zhiping Zheng, and Ping Huang
|
| 4483-4489 |
|
| Galiellalactone induces cell cycle arrest and apoptosis through the ATM/ATR pathway in prostate cancer cells |
|
https://doi.org/10.18632/oncotarget.6606
VÃctor GarcÃa, Maribel Lara-Chica, Irene Cantarero, Olov Sterner, Marco A. Calzado, and Eduardo Muñoz
|
| 4490-4506 |
|
| Genomewide profiling of DNA methylation and gene expression in esophageal squamous cell carcinoma |
|
https://doi.org/10.18632/oncotarget.6607
Chen Chen, Hao Peng, Xiaojie Huang, Ming Zhao, Zhi Li, Ni Yin, Xiang Wang, Fenglei Yu, Bangliang Yin, Yunchang Yuan, and Qianjin Lu
|
| 4507-4521 |
|
| Identification of TIM3 2’fluoro oligonucleotide aptamer by HTSELEX for cancer immunotherapy |
|
https://doi.org/10.18632/oncotarget.6608
Sandra Hervas-Stubbs, Mario M. Soldevilla, Helena Villanueva, Uxua Mancheño, Maurizio Bendandi, and Fernando Pastor
|
| 4522-4530 |
|
| Possible prediction of the response of esophageal squamous cell carcinoma to neoadjuvant chemotherapy based on gene expression profiling |
|
https://doi.org/10.18632/oncotarget.6554
Lu-Yan Shen, Hui Wang, Bin Dong, Wan-Pu Yan, Yao Lin, Qi Shi, and Ke-Neng Chen
|
| 4531-4541 |
|
| The B56γ3 regulatory subunitcontaining protein phosphatase 2A outcompetes Akt to regulate p27KIP1 subcellular localization by selectively dephosphorylating phosphoThr157 of p27KIP1 |
|
https://doi.org/10.18632/oncotarget.6609
Tai-Yu Lai, Chia-Jui Yen, Hung-Wen Tsai, Yu-San Yang, Wei-Fu Hong, and Chi-Wu Chiang
|
| 4542-4558 |
|
| MTDH is an oncogene in multiple myeloma which is suppressed by Bortezomib treatment |
|
https://doi.org/10.18632/oncotarget.6610
Chunyan Gu, Lang Feng, Hailin Peng, Hongbao Yang, Zhenqing Feng, and Ye Yang
|
| 4559-4569 |
|
| A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells |
|
https://doi.org/10.18632/oncotarget.6726
Marina Marani, Alessio Paone, Alessio Fiascarelli, Alberto Macone, Maurizio Gargano, Serena Rinaldo, Giorgio Giardina, Valentino Pontecorvi, David Koes, Lee McDermott, Tianyi Yang, Alessandro Paiardini, Roberto Contestabile, and Francesca CutruzzolÃ
|
| 4570-4583 |
|
| Prognostic value of high EZH2 expression in patients with different types of cancer: a systematic review with metaanalysis |
|
https://doi.org/10.18632/oncotarget.6612
Tao Jiang, Yan Wang, Fei Zhou, Guanghui Gao, Shengxiang Ren, and Caicun Zhou
|
| 4584-4597 |
|
| Heightened BTKdependent cell proliferation in unmutated chronic lymphocytic leukemia confers increased sensitivity to ibrutinib |
|
https://doi.org/10.18632/oncotarget.6727
Ailin Guo, Pin Lu, Natalie Galanina, Chadi Nabhan, Sonali M. Smith, Morton Coleman, and Y. Lynn Wang
|
| 4598-4610 |
|
| Highthroughput qRTPCR validation of blood microRNAs in nonsmall cell lung cancer |
|
https://doi.org/10.18632/oncotarget.6566
Petra Leidinger, Thomas Brefort, Christina Backes, Medea Krapp, Valentina Galata, Markus Beier, Jochen Kohlhaas, Hanno Huwer, Eckart Meese, and Andreas Keller
|
| 4611-4623 |
|
| Deep sequencing of uveal melanoma identifies a recurrent mutation in PLCB4 |
|
https://doi.org/10.18632/oncotarget.6614
Peter Johansson, Lauren G. Aoude, Karin Wadt, William J. Glasson, Sunil K. Warrier, Alex W. Hewitt, Jens Folke Kiilgaard, Steffen Heegaard, Tim Isaacs, Maria Franchina, Christian Ingvar, Tersia Vermeulen, Kevin J. Whitehead, Christopher W. Schmidt, Jane M. Palmer, Judith Symmons, Anne-Marie Gerdes, Göran Jönsson, and Nicholas K. Hayward
|
| 4624-4631 |
|
| Regulation of the epithelial to mesenchymal transition and metastasis by Raf kinase inhibitory proteindependent Notch1 activity |
|
https://doi.org/10.18632/oncotarget.6728
Hae Sook Noh, Young-Sool Hah, Ji Hye Ha, Min Young Kang, Sahib Zada, Sun Young Rha, Sang Soo Kang, Hyun Joon Kim, Jae-Yong Park, June-Ho Byun, Jong Ryeal Hahm, Jeong Kyu Shin, Sang-Ho Jeong, Young-Joon Lee, and Deok Ryong Kim
|
| 4632-4646 |
|
| MicroRNA12255p inhibits proliferation and metastasis of gastric carcinoma through repressing insulin receptor substrate1 and activation of βcatenin signaling |
|
https://doi.org/10.18632/oncotarget.6615
Haiyin Zheng, Fuxing Zhang, Xinjian Lin, Changming Huang, Yiqin Zhang, Yun Li, Jianyin Lin, Wannan Chen, and Xu Lin
|
| 4647-4663 |
|
| Emodin potentiates the antiproliferative effect of interferon α/β by activation of JAK/STAT pathway signaling through inhibition of the 26S proteasome |
|
https://doi.org/10.18632/oncotarget.6616
Yujiao He, Junmei Huang, Ping Wang, Xiaofei Shen, Sheng Li, Lijuan Yang, Wanli Liu, Apichart Suksamrarn, Guolin Zhang, and Fei Wang
|
| 4664-4679 |
|
| EGFRvIII/integrin β3 interaction in hypoxic and vitronectinenriching microenvironment promote GBM progression and metastasis |
|
https://doi.org/10.18632/oncotarget.6730
Zhaoyu Liu, Lei Han, Yucui Dong, Yanli Tan, Yongsheng Li, Manli Zhao, Hui Xie, Huanyu Ju, He Wang, Yu Zhao, Qifan Zheng, Qixue Wang, Jun Su, Chuan Fang, Songbin Fu, Tao Jiang, Jiaren Liu, Xia Li, Chunsheng Kang, and Huan Ren
|
| 4680-4694 |
|
| The role of HDAC2 in chromatin remodelling and response to chemotherapy in ovarian cancer |
|
https://doi.org/10.18632/oncotarget.6618
Rui Huang, Simon P. Langdon, Matthew Tse, Peter Mullen, In Hwa Um, Dana Faratian, and David J. Harrison
|
| 4695-4711 |
|
| Long noncoding RNA Hotair mediated angiogenesis in nasopharyngeal carcinoma by direct and indirect signaling pathways |
|
https://doi.org/10.18632/oncotarget.6731
Wei-ming Fu, Ying-fei Lu, Bao-guang Hu, Wei-cheng Liang, Xiao Zhu, Hai-di Yang, Gang Li, and Jin-fang Zhang
|
| 4712-4723 |
|
| Identification of a novel RNA giant nuclear body in cancer cells |
|
https://doi.org/10.18632/oncotarget.6619
Hong Zhou, Jiawei Zhang, Ying Gu, Xiaoxian Gan, Yichao Gan, Weiwei Zheng, Byung-Wook Kim, Xiaohua Xu, Xiaoya Lu, Qi Dong, Shu Zheng, Wendong Huang, and Rongzhen Xu
|
| 4724-4734 |
|
| miR183 regulates autophagy and apoptosis in colorectal cancer through targeting of UVRAG |
|
https://doi.org/10.18632/oncotarget.6732
Longtao Huangfu, Haihai Liang, Guojie Wang, Xiaomin Su, Linqiang Li, Zhimin Du, Meiyu Hu, Yuechao Dong, Xue Bai, Tianyi Liu, Baofeng Yang, and Hongli Shan
|
| 4735-4745 |
|
| Dysregulated miR6715p / CDR1AS / CDR1 / VSNL1 axis is involved in glioblastoma multiforme |
|
https://doi.org/10.18632/oncotarget.6621
Davide Barbagallo, Angelo Condorelli, Marco Ragusa, Loredana Salito, Mariangela Sammito, Barbara Banelli, Rosario Caltabiano, Giuseppe Barbagallo, Agata Zappalà , Rosalia Battaglia, Matilde Cirnigliaro, Salvatore Lanzafame, Enrico Vasquez, Rosalba Parenti, Federico Cicirata, Cinzia Di Pietro, Massimo Romani, and Michele Purrello
|
| 4746-4759 |
|
| MDSCdecreasing chemotherapy increases the efficacy of cytokineinduced killer cell immunotherapy in metastatic renal cell carcinoma and pancreatic cancer |
|
https://doi.org/10.18632/oncotarget.6734
Zibing Wang, Yuqing Liu, Yong Zhang, Yiman Shang, and Quanli Gao
|
| 4760-4769 |
|
| Low expression of BMPRIB indicates poor prognosis of breast cancer and is insensitive to taxaneanthracycline chemotherapy |
|
https://doi.org/10.18632/oncotarget.6613
Kun Dai, Fengxia Qin, Huikun Zhang, Xiaoli Liu, Caixia Guo, Ming Zhang, Feng Gu, Li Fu, and Yongjie Ma
|
| 4770-4784 |
|
| MicroRNA5843p a novel tumor suppressor and prognostic marker reduces the migration and invasion of human glioma cells by targeting hypoxiainduced ROCK1 |
|
https://doi.org/10.18632/oncotarget.6735
Hao Xue, Xing Guo, Xiao Han, Shaofeng Yan, Jinsen Zhang, Shugang Xu, Tong Li, Xiaofan Guo, Ping Zhang, Xiao Gao, Qinglin Liu, and Gang Li
|
| 4785-4805 |
|
| Angiomirs expression profiling in diffuse large BCell lymphoma |
|
https://doi.org/10.18632/oncotarget.6624
Natália M. Borges, Marcela do Vale Elias, Veruska L. Fook-Alves, Tathiana A. Andrade, Marina Lourenço de Conti, Mariana Petaccia Macedo, Maria Dirlei Begnami, Antônio Hugo J. F. M. Campos, Leina Yukari Etto, Adriana Bruscato Bortoluzzo, Antonio C. Alves, Ken H. Young, and Gisele W. B. Colleoni
|
| 4806-4816 |
|
| miR215 promotes malignant progression of gastric cancer by targeting RUNX1 |
|
https://doi.org/10.18632/oncotarget.6736
Na Li, Qi-Yue Zhang, Jian-Ling Zou, Zhong-Wu Li, Tian-Tian Tian, Bin Dong, Xi-Juan Liu, Sai Ge, Yan Zhu, Jing Gao, and Lin Shen
|
| 4817-4828 |
|
| Hyaluronan stimulates pancreatic cancer cell motility |
|
https://doi.org/10.18632/oncotarget.6617
Xiao-Bo Cheng, Shiro Kohi, Atsuhiro Koga, Keiji Hirata, and Norihiro Sato
|
| 4829-4840 |
|
| PIG7 promotes leukemia cell chemosensitivity via lysosomal membrane permeabilization |
|
https://doi.org/10.18632/oncotarget.6739
Jiazhuo Liu, Leiwen Peng, Ting Niu, Yu Wu, Jianjun Li, Fangfang Wang, Yuhuan Zheng, and Ting Liu
|
| 4841-4859 |
|
| Sorafenib treatment during partial hepatectomy reduces tumorgenesis in an inflammationassociated liver cancer model |
|
https://doi.org/10.18632/oncotarget.6638
Tamar Zahavi, Tali Lanton, Mali Salmon Divon, Asher Salmon, Tamar Peretz, Eithan Galun, Jonathan H. Axelrod, and Amir Sonnenblick
|
| 4860-4870 |
|
| High expression levels of MAGEA9 are correlated with unfavorable survival in lung adenocarcinoma |
|
https://doi.org/10.18632/oncotarget.6741
Xiaolu Zhai, Liqin Xu, Siya Zhang, Huijun Zhu, Guoxin Mao, and Jianfei Huang
|
| 4871-4881 |
|
| Annexin A8 is a novel molecular marker for detecting lymph node metastasis in oral squamous cell carcinoma |
|
https://doi.org/10.18632/oncotarget.6639
Ryota Oka, Koh-ichi Nakashiro, Hiroyuki Goda, Kazuki Iwamoto, Norihiko Tokuzen, and Hiroyuki Hamakawa
|
| 4882-4889 |
|
| PKCδ activated by cMET enhances infiltration of human glioblastoma cells through NOTCH2 signaling |
|
https://doi.org/10.18632/oncotarget.6640
Eunji Hwang, Ki-Chun Yoo, Seok-Gu Kang, Rae-Kwon Kim, Yan-Hong Cui, Hae-June Lee, Min-Jung Kim, Jae-Seong Lee, In-Gyu Kim, Yongjoon Suh, and Su-Jae Lee
|
| 4890-4902 |
|
| Genomewide analysis of EpsteinBarr virus EBV isolated from EBVassociated gastric carcinoma EBVaGC |
|
https://doi.org/10.18632/oncotarget.6751
Ying Liu, Wenjun Yang, Yaqi Pan, Jiafu Ji, Zheming Lu, and Yang Ke
|
| 4903-4914 |
|
| Let7c downregulation in Helicobacter pylorirelated gastric carcinogenesis |
|
https://doi.org/10.18632/oncotarget.6642
Matteo Fassan, Deborah Saraggi, Laura Balsamo, Luciano Cascione, Carlo Castoro, Irene Coati, Marina De Bernard, Fabio Farinati, Vincenza Guzzardo, Nicola Valeri, Carlo Federico Zambon, and Massimo Rugge
|
| 4915-4924 |
|
| Serum level of hepatocyte growth factor is a novel marker of predicting the outcome and resistance to the treatment with trastuzumab in HER2positive patients with metastatic gastric cancer |
|
https://doi.org/10.18632/oncotarget.6753
Naoki Takahashi, Koh Furuta, Hirokazu Taniguchi, Yusuke Sasaki, Hirokazu Shoji, Yoshitaka Honma, Satoru Iwasa, Natsuko Okita, Atsuo Takashima, Ken Kato, Tetsuya Hamaguchi, Yasuhiro Shimada, and Yasuhide Yamada
|
| 4925-4938 |
|
| Adipocytes promote prostate cancer stem cell selfrenewal through amplification of the cholecystokinin autocrine loop |
|
https://doi.org/10.18632/oncotarget.6643
Kai-Dun Tang, Ji Liu, Lidija Jovanovic, Jiyuan An, Michelle M. Hill, Ian Vela, Terence Kin-Wah Lee, Stephanie Ma, Colleen Nelson, Pamela J. Russell, Judith A. Clements, and Ming-Tat Ling
|
| 4939-4948 |
|
| Cell cycledependent resolution of DNA doublestrand breaks |
|
https://doi.org/10.18632/oncotarget.6644
Susanna Ambrosio, Giacomo Di Palo, Giuliana Napolitano, Stefano Amente, Gaetano Ivan Dellino, Mario Faretta, Pier Giuseppe Pelicci, Luigi Lania, and Barbara Majello
|
| 4949-4960 |
|
| The drug target genes show higher evolutionary conservation than nontarget genes |
|
https://doi.org/10.18632/oncotarget.6755
Wenhua Lv, Yongdeng Xu, Yiying Guo, Ziqi Yu, Guanglong Feng, Panpan Liu, Meiwei Luan, Hongjie Zhu, Guiyou Liu, Mingming Zhang, Hongchao Lv, Lian Duan, Zhenwei Shang, Jin Li, Yongshuai Jiang, and Ruijie Zhang
|
| 4961-4971 |
|
| EpsteinBarr virus mirbart15p detection via nasopharyngeal brush sampling is effective for diagnosing nasopharyngeal carcinoma |
|
https://doi.org/10.18632/oncotarget.6649
Xiao-Hui Zheng, Li-Xia Lu, Cui Cui, Ming-Yuan Chen, Xi-Zhao Li, and Wei-Hua Jia
|
| 4972-4980 |
|
| Genetic variants in ERBB4 is associated with chronic hepatitis B virus infection |
|
https://doi.org/10.18632/oncotarget.6650
Yao Liu, Qun Zhou, Xiao-Shun He, Li-Ming Song, Lin Chen, Wei-Juan Jiao, Tong Shen, Su Yao, Hua Wu, Zhi-Bin Hu, Tian-Ming Gao, and Jian-Ming Li
|
| 4981-4992 |
|
| SATB1 and SATB2 play opposing roles in cMyc expression and progression of colorectal cancer |
|
https://doi.org/10.18632/oncotarget.6651
Mohammed A. Mansour, Toshinori Hyodo, Khondker Ayesha Akter, Toshio Kokuryo, Keisuke Uehara, Masato Nagino, and Takeshi Senga
|
| 4993-5006 |
|
| miR101 reverses hypomethylation of the PRDM16 promoter to disrupt mitochondrial function in astrocytoma cells |
|
https://doi.org/10.18632/oncotarget.6652
Qianqian Lei, Xiaoping Liu, Haijuan Fu, Yingnan Sun, Liping Wang, Gang Xu, Wei Wang, Zhibin Yu, Changhong Liu, Peiyao Li, Jianbo Feng, Guiyuan Li, and Minghua Wu
|
| 5007-5022 |
|
| Association of cancer mortality with postdiagnosis overweight and obesity using body mass index |
|
https://doi.org/10.18632/oncotarget.6517
Xinsen Xu, Lei Zhou, Runchen Miao, Wei Chen, Yanyan Zhou, Qing Pang, Kai Qu, and Chang Liu
|
| 5023-5029 |
|
| Biomarkerbased prognostic stratification of young adult glioblastoma |
|
https://doi.org/10.18632/oncotarget.5456
Rui-qi Zhang, Zhifeng Shi, Hong Chen, Nellie Yuk-Fei Chung, Zi Yin, Kay Ka-Wai Li, Danny Tat-Ming Chan, Wai Sang Poon, Jinsong Wu, Liangfu Zhou, Aden Ka-yin Chan, Ying Mao, and Ho-Keung Ng
|
| 5030-5041 |
|
| A genomewide association study identifies WT1 variant with better response to 5fluorouracil pirarubicin and cyclophosphamide neoadjuvant chemotherapy in breast cancer patients |
|
https://doi.org/10.18632/oncotarget.5837
Lina Wu, Lu Yao, Hong Zhang, Tao Ouyang, Jinfeng Li, Tianfeng Wang, Zhaoqing Fan, Tie Fan, Benyao Lin, Cameron C. Yin, and Yuntao Xie
|
| 5042-5052 |
|
| Nomogram basing pretreatment parameters predicting early response for locally advanced rectal cancer with neoadjuvant chemotherapy alone: a subgroup efficacy analysis of FOWARC study |
|
https://doi.org/10.18632/oncotarget.6469
Jianwei Zhang, Yue Cai, Huabin Hu, Ping Lan, Lei Wang, Meijin Huang, Liang Kang, Xiaojian Wu, Hui Wang, Jiayu Ling, Jian Xiao, Jianping Wang, and Yanhong Deng
|
| 5053-5062 |
|
| FGFR1 is an adverse outcome indicator for luminal A breast cancers |
|
https://doi.org/10.18632/oncotarget.6563
Yu-Jie Shi, Julia Y.S. Tsang, Yun-Bi Ni, Siu-Ki Chan, Kui-Fat Chan, and Gary M. Tse
|
| 5063-5073 |
|
| Tumors with highdensity tumor infiltrating lymphocytes constitute a favorable entity in breast cancer: a pooled analysis of four prospective adjuvant trials |
|
https://doi.org/10.18632/oncotarget.6231
Vassiliki Kotoula, Kyriakos Chatzopoulos, Sotiris Lakis, Zoi Alexopoulou, Eleni Timotheadou, Flora Zagouri, George Pentheroudakis, Helen Gogas, Eleni Galani, Ioannis Efstratiou, Thomas Zaramboukas, Angelos Koutras, Gerasimos Aravantinos, Epaminontas Samantas, Amanda Psyrri, Helen Kourea, Mattheos Bobos, Pavlos Papakostas, Paris Kosmidis, Dimitrios Pectasides, and George Fountzilas
|
| 5074-5087 |
|
| Methimazoleinduced cholestatic hepatitis: two cases report and literature review |
|
https://doi.org/10.18632/oncotarget.6144
Hai Zou, Lie Jin, Li-Ren Wang, Martin Braddock, Wen-Wei Cai, and Ming-Hua Zheng
|
| 5088-5091 |
