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A Multiplexed Marker-based Algorithm for Diagnosis of Carcinoma of Unknown Primary Using Circulating Tumor Cells. See Matthew et al.
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Table of Contents
Research Perspectives
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| Blocking the survival of the nastiest by HSP90 inhibition |
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https://doi.org/10.18632/oncotarget.6971
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| 3658-3661 |
Priority Research Papers
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| A multiplexed markerbased algorithm for diagnosis of carcinoma of unknown primary using circulating tumor cells |
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https://doi.org/10.18632/oncotarget.6657
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| 3662-3676 |
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| SHIP represses lung inflammation and inhibits mammary tumor metastasis in BALB/c mice |
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https://doi.org/10.18632/oncotarget.6611
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| 3677-3691 |
Research Papers: Gerotarget (Focus on Aging)
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| Core level regulatory network of osteoblast as molecular mechanism for osteoporosis and treatment |
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https://doi.org/10.18632/oncotarget.6923
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| 3692-3701 |
Research Papers: Immunology
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| Alphafetoprotein still is a valuable diagnostic and prognosis predicting biomarker in hepatitis B virus infectionrelated hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.6913
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| 3702-3708 |
Research Papers: Autophagy and Cell Death
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| Cooperative TRAIL production mediates IFNα/Smac mimeticinduced cell death in TNFαresistant solid cancer cells |
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https://doi.org/10.18632/oncotarget.6915
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| 3709-3725 |
Research Papers: Chromosome
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| DNA demethylation caused by 5Aza2’deoxycytidine induces mitotic alterations and aneuploidy |
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https://doi.org/10.18632/oncotarget.6897
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| 3726-3739 |
Reviews
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| Leptomeningeal metastasis in breast cancer – a systematic review |
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https://doi.org/10.18632/oncotarget.5911
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| 3740-3747 |
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| The role of the oncofetal H19 lncRNA in tumor metastasis: orchestrating the EMTMET decision |
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https://doi.org/10.18632/oncotarget.6387
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| 3748-3765 |
Research Papers
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| Leukemia inhibitory factor promotes EMT through STAT3dependent miR21 induction |
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https://doi.org/10.18632/oncotarget.6756
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| 3777-3790 |
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| Overexpressed CISD2 has prognostic value in human gastric cancer and promotes gastric cancer cell proliferation and tumorigenesis via AKT signaling pathway |
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https://doi.org/10.18632/oncotarget.6302
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| 3791-3805 |
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| CD147 and downstream ADAMTSs promote the tumorigenicity of Kaposi’s sarcomaassociated herpesvirus infected endothelial cells |
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https://doi.org/10.18632/oncotarget.6584
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| 3806-3818 |
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| The pentacyclic triterpenoid plectranthoic acid a novel activator of AMPK induces apoptotic death in prostate cancer cells |
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https://doi.org/10.18632/oncotarget.6625
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| 3819-3831 |
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| Carnitine palmitoyltransferase 1A functions to repress FoxO transcription factors to allow cell cycle progression in ovarian cancer |
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https://doi.org/10.18632/oncotarget.6757
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| 3832-3846 |
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| High efficacy of third generation EGFR inhibitor AZD9291 in a leptomeningeal carcinomatosis model with EGFRmutant lung cancer cells |
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https://doi.org/10.18632/oncotarget.6758
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| 3847-3856 |
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| Signature miRNAs in colorectal cancers were revealed using a bias reduction small RNA deep sequencing protocol |
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https://doi.org/10.18632/oncotarget.6460
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| 3857-3872 |
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| Identification of H7 as a novel peroxiredoxin I inhibitor to induce differentiation of leukemia cells |
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https://doi.org/10.18632/oncotarget.6763
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| 3873-3883 |
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| Overexpression of wildtype EGFR is tumorigenic and denotes a therapeutic target in nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.6461
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| 3884-3896 |
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| Heterogeneity and chronology of 6q15 deletion and ERGfusion in prostate cancer |
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https://doi.org/10.18632/oncotarget.6597
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| 3897-3904 |
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| Genetic deletion of osteopontin in TRAMP mice skews prostate carcinogenesis from adenocarcinoma to aggressive humanlike neuroendocrine cancers |
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https://doi.org/10.18632/oncotarget.6678
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| 3905-3920 |
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| Upregulation of REG3A in colorectal cancer cells confers proliferation and correlates with colorectal cancer risk |
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https://doi.org/10.18632/oncotarget.6473
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| 3921-3933 |
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| Targeting a novel domain in podoplanin for inhibiting plateletmediated tumor metastasis |
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https://doi.org/10.18632/oncotarget.6598
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| 3934-3946 |
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| Primary crossresistance to BRAFV600E MEK1/2 and PI3K/mTORspecific inhibitors in BRAFmutant melanoma cells counteracted by dual pathway blockade |
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https://doi.org/10.18632/oncotarget.6600
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| 3947-3965 |
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| Reduced expression of SET7/9 a histone monomethyltransferase is associated with gastric cancer progression |
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https://doi.org/10.18632/oncotarget.6681
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| 3966-3983 |
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| Simultaneous gene silencing of KRAS and antiapoptotic genes as a multitarget therapy |
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https://doi.org/10.18632/oncotarget.6766
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| 3984-3992 |
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| Exosomes from bulk and stem cells from human prostate cancer have a differential microRNA content that contributes cooperatively over local and premetastatic niche |
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https://doi.org/10.18632/oncotarget.6540
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| 3993-4008 |
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| miR30a inhibits endothelin A receptor and chemoresistance in ovarian carcinoma |
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https://doi.org/10.18632/oncotarget.6546
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| 4009-4023 |
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| Identification of the BRAF V600E mutation in gastroenteropancreatic neuroendocrine tumors |
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https://doi.org/10.18632/oncotarget.6602
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| 4024-4035 |
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| Periostin in tumor microenvironment is associated with poor prognosis and platinum resistance in epithelial ovarian carcinoma |
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https://doi.org/10.18632/oncotarget.6700
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| 4036-4047 |
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| Enhanced expression of LINE1encoded ORF2 protein in early stages of colon and prostate transformation |
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https://doi.org/10.18632/oncotarget.6767
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| 4048-4061 |
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| Inhibiting the anaphase promoting complex/cyclosome induces a metaphase arrest and cell death in multiple myeloma cells |
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https://doi.org/10.18632/oncotarget.6768
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| 4062-4076 |
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| Liposome armed with herpes virusderived gH625 peptide to overcome doxorubicin resistance in lung adenocarcinoma cell lines |
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https://doi.org/10.18632/oncotarget.6013
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| 4077-4092 |
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| Significant blockade of multiple receptor tyrosine kinases by MGCD516 Sitravatinib a novel small molecule inhibitor shows potent antitumor activity in preclinical models of sarcoma |
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https://doi.org/10.18632/oncotarget.6547
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| 4093-4109 |
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| Loss of Ecadherin disrupts ovarian epithelial inclusion cyst formation and collective cell movement in ovarian cancer cells |
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https://doi.org/10.18632/oncotarget.6588
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| 4110-4121 |
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| Autophagy is involved in TGFβ1induced protective mechanisms and formation of cancerassociated fibroblasts phenotype in tumor microenvironment |
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https://doi.org/10.18632/oncotarget.6702
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| 4122-4141 |
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| Combination therapy of RY104 with the γsecretase inhibitor DAPT shows promise in treating HER2amplified breast cancer |
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https://doi.org/10.18632/oncotarget.6769
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| 4142-4154 |
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| Lack of survival advantage with autologous stemcell transplantation in highrisk neuroblastoma consolidated by antiGD2 immunotherapy and isotretinoin |
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https://doi.org/10.18632/oncotarget.6393
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| 4155-4166 |
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| Sphingosine kinase 1 is required for TGFβ mediated fibroblastto myofibroblast differentiation in ovarian cancer |
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https://doi.org/10.18632/oncotarget.6703
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| 4167-4182 |
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| The prognostic role of desmoplastic stroma in pancreatic ductal adenocarcinoma |
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https://doi.org/10.18632/oncotarget.6770
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| 4183-4194 |
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| Epigenetic modification of TLR4 promotes activation of NFκB by regulating methylCpGbinding domain protein 2 and Sp1 in gastric cancer |
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https://doi.org/10.18632/oncotarget.6549
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| 4195-4209 |
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| Clinical implication of voltagedependent anion channel 1 in uterine cervical cancer and its action on cervical cancer cells |
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https://doi.org/10.18632/oncotarget.6704
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| 4210-4225 |
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| Overexpressed EDIL3 predicts poor prognosis and promotes anchorageindependent tumor growth in human pancreatic cancer |
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https://doi.org/10.18632/oncotarget.6772
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| 4226-4240 |
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| Recurrent AKT mutations in human cancers: functional consequences and effects on drug sensitivity |
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https://doi.org/10.18632/oncotarget.6648
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| 4241-4251 |
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| Upregulation of flotillin1 promotes invasion and metastasis by activating TGFβ signaling in nasopharyngeal carcinoma |
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https://doi.org/10.18632/oncotarget.6483
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| 4252-4264 |
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| Metformin increases antitumor activity of MEK inhibitors through GLI1 downregulation in LKB1 positive human NSCLC cancer cells |
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https://doi.org/10.18632/oncotarget.6559
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| 4265-4278 |
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| RASSF10 is an epigenetically inactivated tumor suppressor and independent prognostic factor in hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.6654
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| 4279-4297 |
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| Identification of ovarian cancer subtypespecific network modules and candidate drivers through an integrative genomics approach |
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https://doi.org/10.18632/oncotarget.6774
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| 4298-4309 |
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| CCL3 promotes angiogenesis by dysregulation of miR374b/ VEGFA axis in human osteosarcoma cells |
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https://doi.org/10.18632/oncotarget.6708
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| 4310-4325 |
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| Reactivation of wildtype and mutant p53 by tryptophanolderived oxazoloisoindolinone SLMP531 a novel anticancer smallmolecule |
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https://doi.org/10.18632/oncotarget.6775
|
| 4326-4343 |
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| WWOX modulates the ATRmediated DNA damage checkpoint response |
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https://doi.org/10.18632/oncotarget.6571
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| 4344-4355 |
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| Niacin alleviates TRAILmediated colon cancer cell death via autophagy flux activation |
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https://doi.org/10.18632/oncotarget.5374
|
| 4356-4368 |
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| Adenovirusmediated delivery of herpes simplex virus thymidine kinase administration improves outcome of recurrent highgrade glioma |
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https://doi.org/10.18632/oncotarget.6737
|
| 4369-4378 |
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| Effect of pravastatin on the survival of patients with advanced gastric cancer |
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https://doi.org/10.18632/oncotarget.6777
|
| 4379-4384 |
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| Liver irradiation causes distal bystander effects in the rat brain and affects animal behaviour |
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https://doi.org/10.18632/oncotarget.6596
|
| 4385-4398 |
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| Sildenafil Viagra sensitizes prostate cancer cells to doxorubicinmediated apoptosis through CD95 |
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https://doi.org/10.18632/oncotarget.6749
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| 4399-4413 |
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| GNA13 as a prognostic factor and mediator of gastric cancer progression |
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https://doi.org/10.18632/oncotarget.6780
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| 4414-4427 |
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| Overcoming melanoma resistance to vemurafenib by targeting CCL2induced miR34a miR100 and miR125b |
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https://doi.org/10.18632/oncotarget.6599
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| 4428-4441 |
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| p130Cas scaffold protein regulates ErbB2 stability by altering breast cancer cell sensitivity to autophagy |
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https://doi.org/10.18632/oncotarget.6710
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| 4442-4453 |
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| Induction of MAPK and ROSdependent autophagy and apoptosis in gastric carcinoma by combination of romidepsin and bortezomib |
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https://doi.org/10.18632/oncotarget.6601
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| 4454-4467 |
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| Snail1 is required for the maintenance of the pancreatic acinar phenotype |
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https://doi.org/10.18632/oncotarget.6785
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| 4468-4482 |
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| Diabetes mellitus and the risk of glioma: a metaanalysis |
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https://doi.org/10.18632/oncotarget.6605
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| 4483-4489 |
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| Galiellalactone induces cell cycle arrest and apoptosis through the ATM/ATR pathway in prostate cancer cells |
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https://doi.org/10.18632/oncotarget.6606
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| 4490-4506 |
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| Genomewide profiling of DNA methylation and gene expression in esophageal squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.6607
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| 4507-4521 |
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| Identification of TIM3 2’fluoro oligonucleotide aptamer by HTSELEX for cancer immunotherapy |
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https://doi.org/10.18632/oncotarget.6608
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| 4522-4530 |
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| Possible prediction of the response of esophageal squamous cell carcinoma to neoadjuvant chemotherapy based on gene expression profiling |
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https://doi.org/10.18632/oncotarget.6554
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| 4531-4541 |
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| The B56γ3 regulatory subunitcontaining protein phosphatase 2A outcompetes Akt to regulate p27KIP1 subcellular localization by selectively dephosphorylating phosphoThr157 of p27KIP1 |
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https://doi.org/10.18632/oncotarget.6609
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| 4542-4558 |
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| MTDH is an oncogene in multiple myeloma which is suppressed by Bortezomib treatment |
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https://doi.org/10.18632/oncotarget.6610
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| 4559-4569 |
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| A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells |
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https://doi.org/10.18632/oncotarget.6726
|
| 4570-4583 |
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| Prognostic value of high EZH2 expression in patients with different types of cancer: a systematic review with metaanalysis |
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https://doi.org/10.18632/oncotarget.6612
|
| 4584-4597 |
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| Heightened BTKdependent cell proliferation in unmutated chronic lymphocytic leukemia confers increased sensitivity to ibrutinib |
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https://doi.org/10.18632/oncotarget.6727
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| 4598-4610 |
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| Highthroughput qRTPCR validation of blood microRNAs in nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.6566
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| 4611-4623 |
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| Deep sequencing of uveal melanoma identifies a recurrent mutation in PLCB4 |
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https://doi.org/10.18632/oncotarget.6614
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| 4624-4631 |
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| Regulation of the epithelial to mesenchymal transition and metastasis by Raf kinase inhibitory proteindependent Notch1 activity |
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https://doi.org/10.18632/oncotarget.6728
|
| 4632-4646 |
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| MicroRNA12255p inhibits proliferation and metastasis of gastric carcinoma through repressing insulin receptor substrate1 and activation of βcatenin signaling |
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https://doi.org/10.18632/oncotarget.6615
|
| 4647-4663 |
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| Emodin potentiates the antiproliferative effect of interferon α/β by activation of JAK/STAT pathway signaling through inhibition of the 26S proteasome |
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https://doi.org/10.18632/oncotarget.6616
|
| 4664-4679 |
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| EGFRvIII/integrin β3 interaction in hypoxic and vitronectinenriching microenvironment promote GBM progression and metastasis |
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https://doi.org/10.18632/oncotarget.6730
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| 4680-4694 |
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| The role of HDAC2 in chromatin remodelling and response to chemotherapy in ovarian cancer |
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https://doi.org/10.18632/oncotarget.6618
|
| 4695-4711 |
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| Long noncoding RNA Hotair mediated angiogenesis in nasopharyngeal carcinoma by direct and indirect signaling pathways |
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https://doi.org/10.18632/oncotarget.6731
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| 4712-4723 |
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| Identification of a novel RNA giant nuclear body in cancer cells |
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https://doi.org/10.18632/oncotarget.6619
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| 4724-4734 |
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| miR183 regulates autophagy and apoptosis in colorectal cancer through targeting of UVRAG |
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https://doi.org/10.18632/oncotarget.6732
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| 4735-4745 |
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| Dysregulated miR6715p / CDR1AS / CDR1 / VSNL1 axis is involved in glioblastoma multiforme |
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https://doi.org/10.18632/oncotarget.6621
|
| 4746-4759 |
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| MDSCdecreasing chemotherapy increases the efficacy of cytokineinduced killer cell immunotherapy in metastatic renal cell carcinoma and pancreatic cancer |
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https://doi.org/10.18632/oncotarget.6734
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| 4760-4769 |
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| Low expression of BMPRIB indicates poor prognosis of breast cancer and is insensitive to taxaneanthracycline chemotherapy |
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https://doi.org/10.18632/oncotarget.6613
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| 4770-4784 |
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| MicroRNA5843p a novel tumor suppressor and prognostic marker reduces the migration and invasion of human glioma cells by targeting hypoxiainduced ROCK1 |
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https://doi.org/10.18632/oncotarget.6735
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| 4785-4805 |
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| Angiomirs expression profiling in diffuse large BCell lymphoma |
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https://doi.org/10.18632/oncotarget.6624
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| 4806-4816 |
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| miR215 promotes malignant progression of gastric cancer by targeting RUNX1 |
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https://doi.org/10.18632/oncotarget.6736
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| 4817-4828 |
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| Hyaluronan stimulates pancreatic cancer cell motility |
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https://doi.org/10.18632/oncotarget.6617
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| 4829-4840 |
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| PIG7 promotes leukemia cell chemosensitivity via lysosomal membrane permeabilization |
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https://doi.org/10.18632/oncotarget.6739
|
| 4841-4859 |
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| Sorafenib treatment during partial hepatectomy reduces tumorgenesis in an inflammationassociated liver cancer model |
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https://doi.org/10.18632/oncotarget.6638
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| 4860-4870 |
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| High expression levels of MAGEA9 are correlated with unfavorable survival in lung adenocarcinoma |
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https://doi.org/10.18632/oncotarget.6741
|
| 4871-4881 |
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| Annexin A8 is a novel molecular marker for detecting lymph node metastasis in oral squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.6639
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| 4882-4889 |
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| PKCδ activated by cMET enhances infiltration of human glioblastoma cells through NOTCH2 signaling |
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https://doi.org/10.18632/oncotarget.6640
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| 4890-4902 |
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| Genomewide analysis of EpsteinBarr virus EBV isolated from EBVassociated gastric carcinoma EBVaGC |
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https://doi.org/10.18632/oncotarget.6751
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| 4903-4914 |
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| Let7c downregulation in Helicobacter pylorirelated gastric carcinogenesis |
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https://doi.org/10.18632/oncotarget.6642
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| 4915-4924 |
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| Serum level of hepatocyte growth factor is a novel marker of predicting the outcome and resistance to the treatment with trastuzumab in HER2positive patients with metastatic gastric cancer |
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https://doi.org/10.18632/oncotarget.6753
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| 4925-4938 |
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| Adipocytes promote prostate cancer stem cell selfrenewal through amplification of the cholecystokinin autocrine loop |
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https://doi.org/10.18632/oncotarget.6643
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| 4939-4948 |
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| Cell cycledependent resolution of DNA doublestrand breaks |
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https://doi.org/10.18632/oncotarget.6644
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| 4949-4960 |
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| The drug target genes show higher evolutionary conservation than nontarget genes |
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https://doi.org/10.18632/oncotarget.6755
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| 4961-4971 |
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| EpsteinBarr virus mirbart15p detection via nasopharyngeal brush sampling is effective for diagnosing nasopharyngeal carcinoma |
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https://doi.org/10.18632/oncotarget.6649
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| 4972-4980 |
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| Genetic variants in ERBB4 is associated with chronic hepatitis B virus infection |
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https://doi.org/10.18632/oncotarget.6650
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| 4981-4992 |
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| SATB1 and SATB2 play opposing roles in cMyc expression and progression of colorectal cancer |
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https://doi.org/10.18632/oncotarget.6651
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| 4993-5006 |
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| miR101 reverses hypomethylation of the PRDM16 promoter to disrupt mitochondrial function in astrocytoma cells |
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https://doi.org/10.18632/oncotarget.6652
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| 5007-5022 |
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| Association of cancer mortality with postdiagnosis overweight and obesity using body mass index |
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https://doi.org/10.18632/oncotarget.6517
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| 5023-5029 |
Clinical Research Papers
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| Biomarkerbased prognostic stratification of young adult glioblastoma |
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https://doi.org/10.18632/oncotarget.5456
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| 5030-5041 |
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| A genomewide association study identifies WT1 variant with better response to 5fluorouracil pirarubicin and cyclophosphamide neoadjuvant chemotherapy in breast cancer patients |
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https://doi.org/10.18632/oncotarget.5837
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| 5042-5052 |
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| Nomogram basing pretreatment parameters predicting early response for locally advanced rectal cancer with neoadjuvant chemotherapy alone: a subgroup efficacy analysis of FOWARC study |
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https://doi.org/10.18632/oncotarget.6469
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| 5053-5062 |
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| FGFR1 is an adverse outcome indicator for luminal A breast cancers |
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https://doi.org/10.18632/oncotarget.6563
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| 5063-5073 |
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| Tumors with highdensity tumor infiltrating lymphocytes constitute a favorable entity in breast cancer: a pooled analysis of four prospective adjuvant trials |
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https://doi.org/10.18632/oncotarget.6231
|
| 5074-5087 |
Case Reports
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| Methimazoleinduced cholestatic hepatitis: two cases report and literature review |
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https://doi.org/10.18632/oncotarget.6144
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| 5088-5091 |
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