Vol 8, No 13

uPAR directed-imaging of head-and-neck cancer

HSP90 proteins in the scenario of tumor complexity

Unwanted acquired mutations in Ba/F3 transformation assays

Metabolic reprogramming of the premalignant colonic mucosa is an early event in carcinogenesis

Enhanced antitumor effects by combining an IL-12/anti-DNA fusion protein with avelumab, an anti-PD-L1 antibody

Systematic functional perturbations uncover a prognostic genetic network driving human breast cancer

Caffeine delays oocyte aging and maintains the quality of aged oocytes safely in mouse

Lipid and Alzheimer’s disease genes associated with healthy aging and longevity in healthy oldest-old

Axl acts as a tumor suppressor by regulating LIGHT expression in T lymphoma

NADH autofluorescence, a new metabolic biomarker for cancer stem cells: Identification of Vitamin C and CAPE as natural products targeting “stemness”

Identification of breast cancer recurrence risk factors based on functional pathways in tumor and normal tissues

Impact of exudative diathesis induced by selenium deficiency on LncRNAs and their roles in the oxidative reduction process in broiler chick veins

Metformin-treated cancer cells modulate macrophage polarization through AMPK-NF-κB signaling

Discovery and validation of potential urinary biomarkers for bladder cancer diagnosis using a pseudotargeted GC-MS metabolomics method

32-Phosphorus selectively delivered by listeria to pancreatic cancer demonstrates a strong therapeutic effect

IL-6 secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and metastasis of gastric cancer via JAK2/STAT3 signaling pathway

Overexpression of NSUN2 by DNA hypomethylation is associated with metastatic progression in human breast cancer

Design, sythesis and evaluation of a series of 3- or 4-alkoxy substituted phenoxy derivatives as PPARs agonists

Three single nucleotide polymorphisms of TNFAIP3 gene increase the risk of rheumatoid arthritis

Age-adjusted charlson comorbidity index score as predictor of prolonged postoperative ileus in patients with colorectal cancer who underwent surgical resection

Understanding PSA and its derivatives in prediction of tumor volume: addressing health disparities in prostate cancer risk stratification

Exclusive destruction of mitotic spindles in human cancer cells

The selective MEK1 inhibitor Selumetinib enhances the antitumor activity of everolimus against renal cell carcinoma in vitro and in vivo

Clinical significance of CSF3R, SRSF2 and SETBP1 mutations in chronic neutrophilic leukemia and chronic myelomonocytic leukemia

Effect of captopril on radiation-induced TGF-β1 secretion in EA.Hy926 human umbilical vein endothelial cells

Novel involvement of RhebL1 in sphingosylphosphorylcholine-induced keratin phosphorylation and reorganization: Binding to and activation of AKT1

Diabetic concentrations of metformin inhibit platelet-mediated ovarian cancer cell progression

microRNA-210-3p depletion by CRISPR/Cas9 promoted tumorigenesis through revival of TWIST1 in renal cell carcinoma

Resveratrol induces mitochondria-mediated, caspase-independent apoptosis in murine prostate cancer cells

Berberine-induced autophagic cell death by elevating GRP78 levels in cancer cells

Polymorphisms of ESR1, UGT1A1, HCN1, MAP3K1 and CYP2B6 are associated with the prognosis of hormone receptor-positive early breast cancer

Control of long-distance cell-to-cell communication and autophagosome transfer in squamous cell carcinoma via tunneling nanotubes

Afatinib radiosensitizes head and neck squamous cell carcinoma cells by targeting cancer stem cells

mTOR inhibitors activate PERK signaling and favor viability of gastrointestinal neuroendocrine cell lines

Drp1-dependent mitophagy protects against cisplatin-induced apoptosis of renal tubular epithelial cells by improving mitochondrial function

The PIAS3-Smurf2 sumoylation pathway suppresses breast cancer organoid invasiveness

Imidazoline I₂ receptor inhibitor idazoxan regulates the progression of hepatic fibrosis via Akt-Nrf2-Smad2/3 signaling pathway

The role of hesperetin on osteogenesis of human mesenchymal stem cells and its function in bone regeneration

Relaxin abrogates renal interstitial fibrosis by regulating macrophage polarization via inhibition of Toll-like receptor 4 signaling

Real-time near-infrared fluorescence imaging using cRGD-ZW800-1 for intraoperative visualization of multiple cancer types

Antimicrobial peptide Epinecidin-1 promotes complete skin regeneration of methicillin-resistant Staphylococcus aureus-infected burn wounds in a swine model

Epigenetic silencing of miR-520c leads to induced S100A4 expression and its mediated colorectal cancer progression

Comprehensive analysis of differentially expressed profiles of lncRNAs and construction of miR-133b mediated ceRNA network in colorectal cancer

Differential expression of M3 muscarinic receptors in progressive colon neoplasia and metastasis

Acute lymphoblastic leukemia cells are sensitive to disturbances in protein homeostasis induced by proteasome deubiquitinase inhibition

Pevonedistat, a Nedd8-activating enzyme inhibitor, sensitizes neoplastic B-cells to death receptor-mediated apoptosis

Annonaceous acetogenins mediated up-regulation of Notch2 exerts growth inhibition in human gastric cancer cells in vitro

Proteasome inhibition enhances the efficacy of volasertib-induced mitotic arrest in AML in vitro and prolongs survival in vivo

CDKN2B gene rs1063192 polymorphism decreases the risk of glaucoma

Synergistic effects of the immune checkpoint inhibitor CTLA-4 combined with the growth inhibitor lycorine in a mouse model of renal cell carcinoma

MCMDA: Matrix completion for MiRNA-disease association prediction

Rap2b siRNA significantly enhances the anticancer therapeutic efficacy of Adriamycin in a gold nanoshell-based drug/gene co-delivery system

Identification of patient-specific and tumor-shared T cell receptor sequences in renal cell carcinoma patients

TRAP1 protein signature predicts outcome in human metastatic colorectal carcinoma

Myocardial protection from ischemia/reperfusion injury by exogenous galanin fragment

Variations in the bitterness perception-related genes TAS2R38 and CA6 modify the risk for colorectal cancer in Koreans

Aminopeptidase A initiates tumorigenesis and enhances tumor cell stemness via TWIST1 upregulation in colorectal cancer

Genome-scale analysis identifies GJB2 and ERO1LB as prognosis markers in patients with pancreatic cancer

Identification and analysis of mutational hotspots in oncogenes and tumour suppressors

Granulocyte colony-stimulating factor enhances the therapeutic efficacy of bone marrow mesenchymal stem cell transplantation in rats with experimental acute pancreatitis

Histone lysine methyltransferase G9a is a novel epigenetic target for the treatment of hepatocellular carcinoma

A novel pathogenic splice acceptor site germline mutation in intron 14 of the APC gene in a Chinese family with familial adenomatous polyposis

Autophagy is highly targeted among host comparative proteomes during infection with different virulent RABV strains

Clerosterol from vinegar-baked radix bupleuri modifies drug transport

MicroRNA-34a targets epithelial to mesenchymal transition-inducing transcription factors (EMT-TFs) and inhibits breast cancer cell migration and invasion

miR-494-3p overexpression promotes megakaryocytopoiesis in primary myelofibrosis hematopoietic stem/progenitor cells by targeting SOCS6

M2 polarization of macrophages facilitates arsenic-induced cell transformation of lung epithelial cells

Long non-coding RNA HULC as a potential prognostic biomarker in human cancers: a meta-analysis

Blockade of Rho-associated protein kinase (ROCK) inhibits the contractility and invasion potential of cancer stem like cells

RASSF1A promoter methylation in high-grade serous ovarian cancer: A direct comparison study in primary tumors, adjacent morphologically tumor cell-free tissues and paired circulating tumor DNA

PRSS3 is a prognostic marker in invasive ductal carcinoma of the breast

Grifolin exhibits anti-cancer activity by inhibiting the development and invasion of gastric tumor cells

miR-106b-5p promotes renal cell carcinoma aggressiveness and stem-cell-like phenotype by activating Wnt/β-catenin signalling

Critically short telomeres and toxicity of chemotherapy in early breast cancer

Lynch syndrome-related small intestinal adenocarcinomas

NRIP/DCAF6 stabilizes the androgen receptor protein by displacing DDB2 from the CUL4A-DDB1 E3 ligase complex in prostate cancer

The combination of circulating long noncoding RNAs AK001058, INHBA-AS1, MIR4435-2HG, and CEBPA-AS1 fragments in plasma serve as diagnostic markers for gastric cancer

CD163 as a marker of M2 macrophage, contribute to predict aggressiveness and prognosis of Kazakh esophageal squamous cell carcinoma

Ipilimumab treatment decreases monocytic MDSCs and increases CD8 effector memory T cells in long-term survivors with advanced melanoma

Genomic imbalances are involved in miR-30c and let-7a deregulation in ovarian tumors: implications for HMGA2 expression

MMP8 polymorphism is associated with susceptibility to osteonecrosis of the femoral head in a Chinese Han population

Target of obstructive sleep apnea syndrome merge lung cancer: based on big data platform

Targeting growth hormone receptor in human melanoma cells attenuates tumor progression and epithelial mesenchymal transition via suppression of multiple oncogenic pathways

Reappraisal of XRCC1 Arg194Trp polymorphism and glioma risk: a cumulative meta-analysis

The miR-25-93-106b cluster regulates tumor metastasis and immune evasion via modulation of CXCL12 and PD-L1

ONC201 activates ER stress to inhibit the growth of triple-negative breast cancer cells

Clinical significance of detecting circulating tumor cells in colorectal cancer using subtraction enrichment and immunostaining-fluorescence in situ hybridization (SE-iFISH)

TGF-β–independent CTGF induction regulates cell adhesion mediated drug resistance by increasing collagen I in HCC

Annexin A13 promotes tumor cell invasion in vitro and is associated with metastasis in human colorectal cancer

Genistein inhibits the growth and regulates the migration and invasion abilities of melanoma cells via the FAK/paxillin and MAPK pathways

ATM kinase sustains breast cancer stem-like cells by promoting ATG4C expression and autophagy

Kinase analysis of penile squamous cell carcinoma on multiple platforms to identify potential therapeutic targets

miR-503-5p confers drug resistance by targeting PUMA in colorectal carcinoma

Mitotic read-out genes confer poor outcome in luminal A breast cancer tumors

Preclinical therapeutic efficacy of a novel blood-brain barrier-penetrant dual PI3K/mTOR inhibitor with preferential response in PI3K/PTEN mutant glioma

The addition of celecoxib improves the antitumor effect of cetuximab in colorectal cancer: role of EGFR-RAS-FOXM1-β-catenin signaling axis

Next generation sequencing of extraskeletal myxoid chondrosarcoma

Vitamin D and VDR in cancer cachexia and muscle regeneration

Prognostic role of programmed-death ligand 1 (PD-L1) expressing tumor infiltrating lymphocytes in testicular germ cell tumors

Therapeutic sensitivity to Rac GTPase inhibition requires consequential suppression of mTORC1, AKT, and MEK signaling in breast cancer

HES1 promotes extracellular matrix protein expression and inhibits proliferation and migration in human trabecular meshwork cells under oxidative stress

PIF* promotes brain re-myelination locally while regulating systemic inflammation- clinically relevant multiple sclerosis M.smegmatis model

Patterns of failure and clinical outcomes of definitive radiotherapy for cervical esophageal cancer

Epigenetic inactivation of HOXA11, a novel functional tumor suppressor for renal cell carcinoma, is associated with RCC TNM classification

Implication of vascular endothelial growth factor A and C in revealing diagnostic lymphangiogenic markers in node-positive bladder cancer

SPC24 is critical for anaplastic thyroid cancer progression

Estrogen deficiency is associated with hippocampal morphological remodeling of early postmenopausal mice

Overall survival with crizotinib and next-generation ALK inhibitors in ALK-positive non-small-cell lung cancer (IFCT-1302 CLINALK): a French nationwide cohort retrospective study

JMJD3 suppresses stem cell-like characteristics in breast cancer cells by downregulation of Oct4 independently of its demethylase activity

Limitations in predicting PAM50 intrinsic subtype and risk of relapse score with Ki67 in estrogen receptor-positive HER2-negative breast cancer

Gene regulatory pattern analysis reveals essential role of core transcriptional factors’ activation in triple-negative breast cancer

Interplay between ΔNp63 and miR-138-5p regulates growth, metastasis and stemness of oral squamous cell carcinoma

Correlations between intravoxel incoherent motion (IVIM) parameters and histological findings in rectal cancer: preliminary results

RNA sequencing analysis reveals protective role of kruppel-like factor 3 in colorectal cancer

DNA methylation intratumor heterogeneity in localized lung adenocarcinomas

MiR-519d impedes cisplatin-resistance in breast cancer stem cells by down-regulating the expression of MCL-1

Cell-of-origin of diffuse large B-cell lymphomas determined by the Lymph2Cx assay: better prognostic indicator than Hans algorithm

Hobnail variant of papillary thyroid carcinoma: molecular profiling and comparison to classical papillary thyroid carcinoma, poorly differentiated thyroid carcinoma and anaplastic thyroid carcinoma

Tetraspanin 8 (TSPAN 8) as a potential target for radio-immunotherapy of colorectal cancer

HER2-specific recombinant immunotoxin 4D5scFv-PE40 passes through retrograde trafficking route and forces cells to enter apoptosis

Quantitative proteomic analysis of gastric cancer tissue reveals novel proteins in platelet-derived growth factor B signaling pathway

Low vitamin D status is associated with inflammation in patients with prostate cancer

Karyotyping and analysis of GNAS locus in intramuscular myxomas

A phase I-II trial of fludarabine, bendamustine and rituximab (FBR) in previously treated patients with CLL

Crossing the perspectives of patients, families, and physicians on cancer treatment: A qualitative study

Neuroendocrine tumors of colon and rectum: validation of clinical and prognostic values of the World Health Organization 2010 grading classifications and European Neuroendocrine Tumor Society staging systems

A multicenter phase II study of salvage photodynamic therapy using talaporfin sodium (ME2906) and a diode laser (PNL6405EPG) for local failure after chemoradiotherapy or radiotherapy for esophageal cancer

An early biomarker and potential therapeutic target of RUNX 3 hypermethylation in breast cancer, a system review and meta-analysis

KRAS and TP53 mutations in inflammatory bowel disease-associated colorectal cancer: a meta-analysis

Long non-coding RNAs: a rising biotarget in colorectal cancer

Dysregulations in the PI3K pathway and targeted therapies for head and neck squamous cell carcinoma

Targeting oncogenic vulnerabilities in triple negative breast cancer: biological bases and ongoing clinical studies

RNA binding motif protein 3: a potential biomarker in cancer and therapeutic target in neuroprotection

Consolidative thoracic radiotherapy for extensive stage small cell lung cancer

MicroRNAs in melanoma development and resistance to target therapy

Metabotropic glutamate receptors as a new therapeutic target for malignant gliomas