Oncotarget

Case Reports:

Membranous nephropathy associated with hepatitis C virus infection treated with corticosteroids and Ledipasvir-Sofosbuvir: a case report and review of literature

Qinjie Weng _, Xiao Li, Hong Ren, Jingyuan Xie, Xiaoxia Pan, Jing Xu and Nan Chen

PDF  |  HTML  |  How to cite

Oncotarget. 2017; 8:22299-22303. https://doi.org/10.18632/oncotarget.15397

Metrics: PDF 2282 views  |   HTML 2348 views  |   ?  


Abstract

Qinjie Weng1, Xiao Li1, Hong Ren1, Jingyuan Xie1, Xiaoxia Pan1, Jing Xu1 and Nan Chen1

1 Department of Nephrology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China

Correspondence to:

Nan Chen, email:

Keywords: hepatitis C virus, membranous nephropathy, hepatitis C virus-related glomerulonephritis, Ledipasvir-Sofosbuvir, case report

Received: October 02, 2016 Accepted: January 25, 2017 Published: February 16, 2017

Abstract

Background: Membranous nephropathy (MN) is the most common cause of nephrotic syndrome in adults. As many clinical cases have reported, it may be associated with hepatitis C virus (HCV) infection. Antiviral therapy can be various.

Case summary: We report a case of patient with chronic HCV infection and MN, who presented with was proteinuria. He was treated with ledipasvir and sofosbuvir (Harvoni; Gilead Sciences, Foster City, CA) and was found to be virus-free.

Conclusion: We have reported this case to provide insight into whether Ledipasvir-Sofosbuvir should be administered for HCV-related glomerulonephritis.


Creative Commons License All site content, except where otherwise noted, is licensed under a Creative Commons Attribution 4.0 License.
PII: 15397