Vol 7, No 38

Fusion between cancer cells and macrophages occurs in a murine model of spontaneous neu⁺ breast cancer without increasing its metastatic potential

Phenotypic consequences of somatic mutations in the ataxia-telangiectasia mutated gene in non-small cell lung cancer

The rate of change in declining steroid hormones: a new parameter of healthy aging in men?

AIRE polymorphism, melanoma antigen-specific T cell immunity, and susceptibility to melanoma

Deficient for endoplasmic reticulum calcium sensors Stim1 and Stim2 affects aberrant antibody affinity maturation in B cells

Activation and selective IL-17 response of human Vγ9Vδ2 T lymphocytes by TLR-activated plasmacytoid dendritic cells

P2Y₆ contributes to ovalbumin-induced allergic asthma by enhancing mast cell function in mice

Repair of UVB-induced DNA damage is reduced in melanoma due to low XPC and global genome repair

PPARγ agonists promote differentiation of cancer stem cells by restraining YAP transcriptional activity

Vhl deletion in renal epithelia causes HIF-1α-dependent, HIF-2α-independent angiogenesis and constitutive diuresis

Role of mir-15a/16-1 in early B cell development in a mouse model of chronic lymphocytic leukemia

Genome-wide gain-of-function screen for genes that induce epithelial-to-mesenchymal transition in breast cancer

The bile acid receptor GPBAR1 (TGR5) is expressed in human gastric cancers and promotes epithelial-mesenchymal transition in gastric cancer cell lines

NUMB negatively regulates the epithelial-mesenchymal transition of triple-negative breast cancer by antagonizing Notch signaling

RWCFusion: identifying phenotype-specific cancer driver gene fusions based on fusion pair random walk scoring method

Exogenous IL-33 overcomes T cell tolerance in murine acute myeloid leukemia

Novel B55α-PP2A mutations in AML promote AKT T308 phosphorylation and sensitivity to AKT inhibitor-induced growth arrest

Oral kanglaite injection (KLTI) attenuates the lung cancer-promoting effect of high-fat diet (HFD)-induced obesity

Interleukin-6 increases matrix metalloproteinase-14 (MMP-14) levels via down-regulation of p53 to drive cancer progression

Lysosomal acid lipase in mesenchymal stem cell stimulation of tumor growth and metastasis

The histone methyltransferase G9a as a therapeutic target to override gemcitabine resistance in pancreatic cancer

Oncogenic effects of urotensin-II in cells lacking tuberous sclerosis complex-2

MiR-4653-3p and its target gene FRS2 are prognostic biomarkers for hormone receptor positive breast cancer patients receiving tamoxifen as adjuvant endocrine therapy

IL-13/STAT6 signaling plays a critical role in the epithelial-mesenchymal transition of colorectal cancer cells

Comprehensive N-glycan profiles of hepatocellular carcinoma reveal association of fucosylation with tumor progression and regulation of FUT8 by microRNAs

Identification and functional analysis of long non-coding RNAs in human and mouse early embryos based on single-cell transcriptome data

Chronic exposure to cigarette smoke leads to activation of p21 (RAC1)-activated kinase 6 (PAK6) in non-small cell lung cancer cells

Overcoming chemoresistance in prostate cancer with Chinese medicine Tripterygium wilfordii via multiple mechanisms

TGF-β1 stimulates migration of type II endometrial cancer cells by down-regulating PTEN via activation of SMAD and ERK1/2 signaling pathways

ADAMTS6 suppresses tumor progression via the ERK signaling pathway and serves as a prognostic marker in human breast cancer

A greater number of dissected lymph nodes is associated with more favorable outcomes in bladder cancer treated by radical cystectomy: a meta-analysis

Predicting the cell death responsiveness and sensitization of glioma cells to TRAIL and temozolomide

miR-450b-5p induced by oncogenic KRAS is required for colorectal cancer progression

Dynamics of PBMC gene expression in hepatitis C virus genotype 1-infected patients during combined peginterferon/ribavirin therapy

Role of the immune system in the peritoneal tumor spread of high grade serous ovarian cancer

Up-regulation of miR-187 modulates the advances of oral carcinoma by targeting BARX2 tumor suppressor

Role of high expression levels of STK39 in the growth, migration and invasion of non-small cell type lung cancer cells

Nomogram for preoperative estimation of long-term survival of patients who underwent curative resection with hepatocellular carcinoma beyond Barcelona clinic liver cancer stage A1

Elevated O-GlcNAcylation promotes gastric cancer cells proliferation by modulating cell cycle related proteins and ERK 1/2 signaling

Sulforaphane-induced apoptosis involves the type 1 IP₃ receptor

Methotrexate therapy of T-cell large granular lymphocytic leukemia impact of STAT3 mutation

Identification and characterization of the intercellular adhesion molecule-2 gene as a novel p53 target

Inhibition of interleukin-1β-induced endothelial tissue factor expression by the synthetic cannabinoid WIN 55,212-2

Ets2 knockdown inhibits tumorigenesis in esophageal squamous cell carcinoma in vivo and in vitro

Stromal remodeling by the BET bromodomain inhibitor JQ1 suppresses the progression of human pancreatic cancer

Deregulated FADD expression and phosphorylation in T-cell lymphoblastic lymphoma

The role of nerve microenvironment for neurofibroma development

Salvianolic acid B, a novel autophagy inducer, exerts antitumor activity as a single agent in colorectal cancer cells

YM155 sensitizes TRAIL-induced apoptosis through cathepsin S-dependent down-regulation of Mcl-1 and NF-κB-mediated down-regulation of c-FLIP expression in human renal carcinoma Caki cells

Cumulative score based on preoperative plasma fibrinogen and serum C-reactive protein could predict long-term survival for esophageal squamous cell carcinoma

Therapeutic relevance of the protein phosphatase 2A in cancer

Pregnancy-specific glycoprotein 9 (PSG9), a driver for colorectal cancer, enhances angiogenesis via activation of SMAD4

Targeted sequencing reveals TP53 as a potential diagnostic biomarker in the post-treatment surveillance of head and neck cancer

The requirement of SEPT2 and SEPT7 for migration and invasion in human breast cancer via MEK/ERK activation

Novel biomarkers of resistance of pancreatic cancer cells to oncolytic vesicular stomatitis virus

RhoGDIα suppresses self-renewal and tumorigenesis of glioma stem cells

Ligand dependent restoration of human TLR3 signaling and death in p53 mutant cells

Protective effects of Huangqin Decoction against ulcerative colitis and associated cancer in mice

Generation of TALEN-mediated FH knockout rat model

KLRG1 restricts memory T cell antitumor immunity

Patients with urothelial carcinoma have poor renal outcome regardless of whether they receive nephrouretectomy

CD73 is associated with poor prognosis in HNSCC

Neferine inhibits proliferation and collagen synthesis induced by high glucose in cardiac fibroblasts and reduces cardiac fibrosis in diabetic mice

Genetic variants of genes in the Notch signaling pathway predict overall survival of non-small cell lung cancer patients in the PLCO study

Novel chemokine-like activities of histones in tumor metastasis

LncRNA ANRIL is up-regulated in nasopharyngeal carcinoma and promotes the cancer progression via increasing proliferation, reprograming cell glucose metabolism and inducing side-population stem-like cancer cells

Mutational profiling of non-small-cell lung cancer patients resistant to first-generation EGFR tyrosine kinase inhibitors using next generation sequencing

Mesenchymal stem cells provide prophylaxis against acute graft-versus-host disease following allogeneic hematopoietic stem cell transplantation: A meta-analysis of animal models

A bivalent promoter contributes to stress-induced plasticity of CXCR4 in Ewing sarcoma

CK2 targeted RNAi therapeutic delivered via malignant cell-directed tenfibgen nanocapsule: dose and molecular mechanisms of response in xenograft prostate tumors

PRIMA-1 targets the vulnerability of multiple myeloma of deregulated protein homeostasis through the perturbation of ER stress via p73 demethylation

IL-8 promotes HNSCC progression on CXCR1/2-meidated NOD1/RIP2 signaling pathway

Synergistic effect of reduced polypeptide micelle for co-delivery of doxorubicin and TRAIL against drug-resistance in breast cancer

Simultaneous detection of BRCA mutations and large genomic rearrangements in germline DNA and FFPE tumor samples

Low-dose Actinomycin-D treatment re-establishes the tumoursuppressive function of P53 in RELA-positive ependymoma

Nucks1 synergizes with Trp53 to promote radiation lymphomagenesis in mice

Metabolic shift toward oxidative phosphorylation in docetaxel resistant prostate cancer cells

Suppressive effects of sodium fluoride on cultured splenic lymphocyte proliferation in mice

Validation of the high-performance of pyrosequencing for clinical MGMT testing on a cohort of glioblastoma patients from a prospective dedicated multicentric trial

The cytokine-cosmc signaling axis upregulates the tumor-associated carbohydrate antigen Tn

Infarct volume after glioblastoma surgery as an independent prognostic factor

Activation of GRP/GRP-R signaling contributes to castration-resistant prostate cancer progression

Candidate germline polymorphisms of genes belonging to the pathways of four drugs used in osteosarcoma standard chemotherapy associated with risk, survival and toxicity in non-metastatic high-grade osteosarcoma

Sorafenib inhibits cell growth but fails to enhance radio- and chemosensitivity of glioblastoma cell lines

Association between whole grain intake and all-cause mortality: a meta-analysis of cohort studies

CXCL12-CXCR7 axis contributes to the invasive phenotype of pancreatic cancer

Ferritin heavy chain is a negative regulator of ovarian cancer stem cell expansion and epithelial to mesenchymal transition

Plasma microRNA profiles: identification of miR-23a as a novel biomarker for chemoresistance in esophageal squamous cell carcinoma

Clinical significance of putative markers of cancer stem cells in gastric cancer: A retrospective cohort study

Ataxia-telangiectasia mutated activation mediates tumor necrosis factor-alpha induced MMP-13 up-regulation and metastasis in lung cancer cells

A polymorphism rs4705341 in the flanking region of miR-143/145 predicts risk and prognosis of colorectal cancer

Chk1 inhibition significantly potentiates activity of nucleoside analogs in TP53-mutated B-lymphoid cells

Diacetoxyscirpenol as a new anticancer agent to target hypoxia-inducible factor 1

A novel inflammation-based prognostic score for patients with esophageal squamous cell carcinoma: the c-reactive protein/prognostic nutritional index ratio

A polycomb-mediated epigenetic field defect precedes invasive cervical carcinoma

Lactoferrin selectively triggers apoptosis in highly metastatic breast cancer cells through inhibition of plasmalemmal V-H+-ATPase

PADI4 has genetic susceptibility to gastric carcinoma and upregulates CXCR2, KRT14 and TNF-α expression levels

Gemcitabine enhances cell invasion via activating HAb18G/CD147-EGFR-pSTAT3 signaling

Expression/activation of α5β1 integrin is linked to the β-catenin signaling pathway to drive migration in glioma cells

Knockdown of NEAT1 restrained the malignant progression of glioma stem cells by activating microRNA let-7e

TIPE2 suppresses angiogenesis and non-small cell lung cancer (NSCLC) invasiveness via inhibiting Rac1 activation and VEGF expression

Dual targeting of androgen receptor and mTORC1 by salinomycin in prostate cancer

Promising pharmacological profile of a Kunitz-type inhibitor in murine renal cell carcinoma model

Biological effect of an alternating electric field on cell proliferation and synergistic antimitotic effect in combination with ionizing radiation

Somatic mutations in plasma cell-free DNA are diagnostic markers for esophageal squamous cell carcinoma recurrence

Induction of exportin-5 expression during melanoma development supports the cellular behavior of human malignant melanoma cells

A single nucleotide polymorphism in the 3’-UTR of STAT3 regulates its expression and reduces risk of pancreatic cancer in a Chinese population

MicroRNA-34a regulates doxorubicin-induced cardiotoxicity in rat

eIF5B increases ASAP1 expression to promote HCC proliferation and invasion

Suppression of PC-1/PrLZ sensitizes prostate cancer cells to ionizing radiation by attenuating DNA damage repair and inducing autophagic cell death

Interleukin-6 expression contributes to lapatinib resistance through maintenance of stemness property in HER2-positive breast cancer cells

miR-223 increases gallbladder cancer cell sensitivity to docetaxel by downregulating STMN1

Tetraspanin CD81 is an adverse prognostic marker in acute myeloid leukemia

Inhibition of insulin-like growth factor II (IGF-II)-dependent cell growth by multidentate pentamannosyl 6-phosphate-based ligands targeting the mannose 6-phosphate/IGF-II receptor

Prevalence of human papillomavirus infection and genotyping for population-based cervical screening in developed regions in China

Human astrocytes secrete IL-6 to promote glioma migration and invasion through upregulation of cytomembrane MMP14

Natural nitration of CXCL12 reduces its signaling capacity and chemotactic activity in vitro and abrogates intra-articular lymphocyte recruitment in vivo

Dihydroartemisinin suppresses pancreatic cancer cells via a microRNA-mRNA regulatory network

Long noncoding RNA CCAT1 acts as an oncogene and promotes chemoresistance in docetaxel-resistant lung adenocarcinoma cells

Soluble PD-L1: A biomarker to predict progression of autologous transplantation in patients with multiple myeloma

De-novo NAD⁺ synthesis regulates SIRT1-FOXO1 apoptotic pathway in response to NQO1 substrates in lung cancer cells

Long non-coding RNA NKILA inhibits migration and invasion of tongue squamous cell carcinoma cells via suppressing epithelial-mesenchymal transition

Generation and molecular characterization of pancreatic cancer patient-derived xenografts reveals their heterologous nature

Integrated analysis of genome-wide DNA methylation and gene expression profiles identifies potential novel biomarkers of rectal cancer

Mechanism of suppressors of cytokine signaling 1 inhibition of epithelial-mesenchymal transition signaling through ROS regulation in colon cancer cells: suppression of Src leading to thioredoxin up-regulation

The novel compound STK405759 is a microtubule-targeting agent with potent and selective cytotoxicity against multiple myeloma in vitro and in vivo

(-)-Guaiol regulates RAD51 stability via autophagy to induce cell apoptosis in non-small cell lung cancer

Evidence from a large-scale meta-analysis indicates eczema reduces the incidence of glioma

Optimization of the tumor microenvironment and nanomedicine properties simultaneously to improve tumor therapy

Combining antiangiogenic therapy with neoadjuvant chemotherapy increases treatment efficacy in stage IIIA (N2) non-small cell lung cancer without increasing adverse effects

Recurrent mutations in NF-κB pathway components, KMT2D, and NOTCH1/2 in ocular adnexal MALT-type marginal zone lymphomas

The independent association of mean platelet volume with overall survival in multiple myeloma

Sirolimus and metformin synergistically inhibit hepatocellular carcinoma cell proliferation and improve long-term survival in patients with HCC related to hepatitis B virus induced cirrhosis after liver transplantation

Initial intracranial pressure as a prognosticator in head-injured patients undergoing decompressive craniectomy

Alterations of lymph nodes evaluation after colon cancer resection: patient and tumor heterogeneity should be taken into consideration

Sitagliptin and heart failure hospitalization in patients with type 2 diabetes

Predictive value of pedicle involvement with MRI in spine metastases

Occult HBV infection in HCC and cirrhotic tissue of HBsAg-negative patients: a virological and clinical study

The effect of radiotherapy in liver-confined but non-resectable Barcelona Clinic Liver Cancer stage C large hepatocellular carcinoma

Technical challenges in the isolation and analysis of circulating tumor cells

AKT-ions with a TWIST between EMT and MET

The emerging role of miR-506 in cancer

HVPG signature: A prognostic and predictive tool in hepatocellular carcinoma