Priority Research Papers

PI3K/Akt promotes feedforward mTORC2 activation through IKKα	PI3K/Akt promotes feedforward mTORC2 activation through IKKα
https://doi.org/10.18632/oncotarget.8383 Han C. Dan, Ricardo J. Antonia, and Albert S. Baldwin
21064-21075

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Human platelets repurposed as vehicles for in vivo imaging of myeloma xenotransplants	Human platelets repurposed as vehicles for in vivo imaging of myeloma xenotransplants
https://doi.org/10.18632/oncotarget.8517 Lu Dai, Ning Gu, Bao-An Chen, and Gerard Marriott
21076-21090

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Na+/H+ exchanger NHE1 regulation modulates metastatic potential and epithelialmesenchymal transition of triplenegative breast cancer cells	Na+/H+ exchanger NHE1 regulation modulates metastatic potential and epithelialmesenchymal transition of triplenegative breast cancer cells
https://doi.org/10.18632/oncotarget.8520 Schammim Ray Amith, Jodi Marie Wilkinson, and Larry Fliegel
21091-21113

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A monoclonal antibody against the Wnt signaling inhibitor dickkopf1 inhibits osteosarcoma metastasis in a preclinical model	A monoclonal antibody against the Wnt signaling inhibitor dickkopf1 inhibits osteosarcoma metastasis in a preclinical model
https://doi.org/10.18632/oncotarget.8522 Seth D. Goldstein, Matteo Trucco, Wendy Bautista Guzman, Masanori Hayashi, and David M. Loeb
21114-21123

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Research Papers: Gerotarget (Focus on Aging)

Agingrelated elevation of sphingoid bases shortens yeast chronological life span by compromising mitochondrial function	Agingrelated elevation of sphingoid bases shortens yeast chronological life span by compromising mitochondrial function
https://doi.org/10.18632/oncotarget.8195 Jae Kyo Yi, Ruijuan Xu, Eunmi Jeong, Izolda Mileva, Jean-Philip Truman, Chih-li Lin, Kai Wang, Justin Snider, Sally Wen, Lina M. Obeid, Yusuf A. Hannun, and Cungui Mao
21124-21144

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Tissue repair genes: the TiRe database and its implication for skin wound healing	Tissue repair genes: the TiRe database and its implication for skin wound healing
https://doi.org/10.18632/oncotarget.8501 Hagai Yanai, Arie Budovsky, Robi Tacutu, Thomer Barzilay, Amir Abramovich, Rolf Ziesche, and Vadim E. Fraifeld
21145-21155

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Activation of bitter taste receptors tas2rs relaxes detrusor smooth muscle and suppresses overactive bladder symptoms	Activation of bitter taste receptors tas2rs relaxes detrusor smooth muscle and suppresses overactive bladder symptoms
https://doi.org/10.18632/oncotarget.8549 Kui Zhai, Zhiguang Yang, Xiaofei Zhu, Eric Nyirimigabo, Yue Mi, Yan Wang, Qinghua Liu, Libo Man, Shiliang Wu, Jie Jin, and Guangju Ji
21156-21167

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Research Papers: Pathology

A new immunization and treatment strategy for mouse mammary tumor virus MMTV associated cancers	A new immunization and treatment strategy for mouse mammary tumor virus MMTV associated cancers
https://doi.org/10.18632/oncotarget.7762 Ori Braitbard, Maayan Roniger, Allan Bar-Sinai, Dana Rajchman, Tamar Gross, Hillel Abramovitch, Marco La Ferla, Sara Franceschi, Francesca Lessi, Antonio Giuseppe Naccarato, Chiara M. Mazzanti, Generoso Bevilacqua, and Jacob Hochman
21168-21180

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Evaluation of p16/Ki67 dual staining in detection of cervical precancer and cancers: a multicenter study in China	Evaluation of p16/Ki67 dual staining in detection of cervical precancer and cancers: a multicenter study in China
https://doi.org/10.18632/oncotarget.8307 Lu-Lu Yu, Wen Chen, Xiao-Qin Lei, Yu Qin, Ze-Ni Wu, Qin-Jing Pan, Xun Zhang, Bai-Feng Chang, Shao-Kai Zhang, Hui-Qin Guo, and You-Lin Qiao
21181-21189

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Ki67 proliferation index but not mitotic thresholds integrates the molecular prognostic stratification of lower grade gliomas	Ki67 proliferation index but not mitotic thresholds integrates the molecular prognostic stratification of lower grade gliomas
https://doi.org/10.18632/oncotarget.8498 Eleonora Duregon, Luca Bertero, Alessandra Pittaro, Riccardo Soffietti, Roberta Rudà, Morena Trevisan, Mauro Papotti, Laura Ventura, Rebecca Senetta, and Paola Cassoni
21190-21198

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Research Papers: Immunology

An optimized single chain TCR scaffold relying on the assembly with the native CD3complex prevents residual mispairing with endogenous TCRs in human Tcells	An optimized single chain TCR scaffold relying on the assembly with the native CD3complex prevents residual mispairing with endogenous TCRs in human Tcells
https://doi.org/10.18632/oncotarget.8385 Diana Knies, Sebastian Klobuch, Shao-An Xue, Matthias Birtel, Hakim Echchannaoui, Oezlem Yildiz, Tana Omokoko, Philippe Guillaume, Pedro Romero, Hans Stauss, Ugur Sahin, Wolfgang Herr, Matthias Theobald, Simone Thomas, and Ralf-Holger Voss
21199-21221

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LiangGeSan a classic traditional Chinese medicine formula protects against lipopolysaccharideinduced inflammation through cholinergic antiinflammatory pathway	LiangGeSan a classic traditional Chinese medicine formula protects against lipopolysaccharideinduced inflammation through cholinergic antiinflammatory pathway
https://doi.org/10.18632/oncotarget.8452 Jun-Shan Liu, Xi-Duan Wei, Zi-Bin Lu, Pei Xie, Hong-Ling Zhou, Yu-Yao Chen, Jia-Mei Ma, and Lin-Zhong Yu
21222-21234

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Reviews

Autophagyassociated immune responses and cancer immunotherapy	Autophagyassociated immune responses and cancer immunotherapy
https://doi.org/10.18632/oncotarget.6908 Hongming Pan, Liuxi Chen, Yinghua Xu, Weidong Han, Fang Lou, Weiqiang Fei, Shuiping Liu, Zhao Jing, and Xinbing Sui
21235-21246

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VEGF pathway targeting agents vessel normalization and tumor drug uptake: from bench to bedside	VEGF pathway targeting agents vessel normalization and tumor drug uptake: from bench to bedside
https://doi.org/10.18632/oncotarget.6918 Marlous Arjaans, Carolina P. Schröder, Sjoukje F. Oosting, Urania Dafni, Josée E. Kleibeuker, and Elisabeth G.E. de Vries
21247-21258

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Beyond evidencebased data: scientific rationale and tumor behavior to drive sequential and personalized therapeutic strategies for the treatment of metastatic renal cell carcinoma	Beyond evidencebased data: scientific rationale and tumor behavior to drive sequential and personalized therapeutic strategies for the treatment of metastatic renal cell carcinoma
https://doi.org/10.18632/oncotarget.7267 Lorena Incorvaia, Giuseppe Bronte, Viviana Bazan, Giuseppe Badalamenti, Sergio Rizzo, Gianni Pantuso, Clara Natoli, and Antonio Russo
21259-21271

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Research Papers

Identification of cis and transacting elements regulating calretinin expression in mesothelioma cells	Identification of cis and transacting elements regulating calretinin expression in mesothelioma cells
https://doi.org/10.18632/oncotarget.7114 Jelena Kresoja-Rakic, Esra Kapaklikaya, Gabriela Ziltener, Damian Dalcher, Raffaella Santoro, Brock C. Christensen, Kevin C. Johnson, Beat Schwaller, Walter Weder, Rolf A. Stahel, and Emanuela Felley-Bosco
21272-21286

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Longterm prognostic implications and therapeutic target role of hexokinase II in patients with nasopharyngeal carcinoma	Longterm prognostic implications and therapeutic target role of hexokinase II in patients with nasopharyngeal carcinoma
https://doi.org/10.18632/oncotarget.7116 Meng-Xia Zhang, Yi-Jun Hua, Hai-Yun Wang, Ling Zhou, Hai-Qiang Mai, Xiang Guo, Chong Zhao, Wen-Lin Huang, Ming-Huang Hong, and Ming-Yuan Chen
21287-21297

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Imprinting defects at human 14q32 locus alters gene expression and is associated with the pathobiology of osteosarcoma	Imprinting defects at human 14q32 locus alters gene expression and is associated with the pathobiology of osteosarcoma
https://doi.org/10.18632/oncotarget.6965 Jingmin Shu, Lihua Li, Anne E. Sarver, Emily A. Pope, Jyotika Varshney, Venugopal Thayanithy, Logan Spector, David A. Largaespada, Clifford J. Steer, and Subbaya Subramanian
21298-21314

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Metformin inhibits 17βestradiolinduced epithelialtomesenchymal transition via βKlothorelated ERK1/2 signaling and AMPKα signaling in endometrial adenocarcinoma cells	Metformin inhibits 17βestradiolinduced epithelialtomesenchymal transition via βKlothorelated ERK1/2 signaling and AMPKα signaling in endometrial adenocarcinoma cells
https://doi.org/10.18632/oncotarget.7040 Zhao Liu, Shasha Qi, Xingbo Zhao, Mingjiang Li, Sentai Ding, Jiaju Lu, and Hui Zhang
21315-21331

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Genetic and epigenetic background and protein expression profiles in relation to telomerase activation in medullary thyroid carcinoma	Genetic and epigenetic background and protein expression profiles in relation to telomerase activation in medullary thyroid carcinoma
https://doi.org/10.18632/oncotarget.7237 Na Wang, Hanna Kjellin, Anastasios Sofiadis, Omid Fotouhi, C. Christofer Juhlin, Martin Bäckdah, Jan Zedenius, Dawei Xu, Janne Lehtiö, and Catharina Larsson
21332-21346

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Survival benefit of surgery with radiotherapy vs surgery alone to patients with T23N0M0 stage esophageal adenocarcinoma	Survival benefit of surgery with radiotherapy vs surgery alone to patients with T23N0M0 stage esophageal adenocarcinoma
https://doi.org/10.18632/oncotarget.7256 Yaqi Song, Guangzhou Tao, Qing Guo, Xi Yang, Hongcheng Zhu, Wanwei Wang, and Xinchen Sun
21347-21352

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Molecular spectrum of TP53 mutations in plasma cell dyscrasias by next generation sequencing: an Italian cohort study and overview of the literature	Molecular spectrum of TP53 mutations in plasma cell dyscrasias by next generation sequencing: an Italian cohort study and overview of the literature
https://doi.org/10.18632/oncotarget.7241 Marta Lionetti, Marzia Barbieri, Martina Manzoni, Sonia Fabris, Cecilia Bandini, Katia Todoerti, Filomena Nozza, Davide Rossi, Pellegrino Musto, Luca Baldini, and Antonino Neri
21353-21361

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EPH/ephrin profile and EPHB2 expression predicts patient survival in breast cancer	EPH/ephrin profile and EPHB2 expression predicts patient survival in breast cancer
https://doi.org/10.18632/oncotarget.7246 Anna-Maria Husa, Željana Magić, Malin Larsson, Tommy Fornander, and Gizeh Pérez-Tenorio
21362-21380

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Nitrilase 1 modulates lung tumor progression in vitro and in vivo	Nitrilase 1 modulates lung tumor progression in vitro and in vivo
https://doi.org/10.18632/oncotarget.7820 Yong Antican Wang, Yunguang Sun, Justin M. Le Blanc, Charalambos Solomides, Tingting Zhan, and Bo Lu
21381-21392

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A genetic study and metaanalysis of the genetic predisposition of prostate cancer in a Chinese population	A genetic study and metaanalysis of the genetic predisposition of prostate cancer in a Chinese population
https://doi.org/10.18632/oncotarget.7250 Jacek Marzec, Xueying Mao, Meiling Li, Meilin Wang, Ninghan Feng, Xin Gou, Guomin Wang, Zan Sun, Jianfeng Xu, Hua Xu, Xiaoping Zhang, Shan-Chao Zhao, Guoping Ren, Yongwei Yu, Yudong Wu, Ji Wu, Yao Xue, Bo Zhou, Yanling Zhang, Xingxing Xu, Jie Li, Weiyang He, Sara Benlloch, Helen Ross-Adams, Li Chen, Jucong Li, Yingqia Hong, Zsofia Kote-Jarai, Xingang Cui, Jianguo Hou, Jianming Guo, Lei Xu, Changjun Yin, Yuanping Zhou, David E. Neal, Tim Oliver, Guangwen Cao, Zhengdong Zhang, Douglas F. Easton, Claude Chelala, The PRACTICAL Consortium, The CHIPGECS Group, Ali Amin Al Olama, Rosalind A. Eeles, Hongwei Zhang, and Yong-Jie Lu
21393-21403

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Knockdown of Golgi phosphoprotein 2 inhibits hepatocellular carcinoma cell proliferation and motility	Knockdown of Golgi phosphoprotein 2 inhibits hepatocellular carcinoma cell proliferation and motility
https://doi.org/10.18632/oncotarget.7271 Yiming Liu, Xiaodi Zhang, Ting Sun, Junchang Jiang, Ying Li, Mingliang Chen, Zhen Wei, Weiqin Jiang, and Linfu Zhou
21404-21415

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TNFSF10/TRAIL regulates human T4 effector memory lymphocyte radiosensitivity and predicts radiationinduced acute and subacute dermatitis	TNFSF10/TRAIL regulates human T4 effector memory lymphocyte radiosensitivity and predicts radiationinduced acute and subacute dermatitis
https://doi.org/10.18632/oncotarget.7893 Jan Baijer, Nathalie Déchamps, Hervé Perdry, Pablo Morales, Sarah Kerns, Alexandre Vasilescu, Sylvain Baulande, David Azria, Paul Henri Roméo, and Annette Schmitz
21416-21427

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RHAMM splice variants confer radiosensitivity in human breast cancer cell lines	RHAMM splice variants confer radiosensitivity in human breast cancer cell lines
https://doi.org/10.18632/oncotarget.7258 Alexandra Schütze, Christian Vogeley, Tobias Gorges, Sören Twarock, Jonas Butschan, Anna Babayan, Diana Klein, Shirley K. Knauer, Eric Metzen, Volkmar Müller, Verena Jendrossek, Klaus Pantel, Karin Milde-Langosch, Jens W. Fischer, and Katharina Röck
21428-21440

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mir329 restricts tumor growth by targeting grb2 in pancreatic cancer	mir329 restricts tumor growth by targeting grb2 in pancreatic cancer
https://doi.org/10.18632/oncotarget.7375 Xinjing Wang, Xiongxiong Lu, Tian Zhang, Chenlei Wen, Minmin Shi, Xiaomei Tang, Hao Chen, Chenghong Peng, Hongwei Li, Yuan Fang, Xiaxing Deng, and Baiyong Shen
21441-21453

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PSMB8 and PBK as potential gastric cancer subtypespecific biomarkers associated with prognosis	PSMB8 and PBK as potential gastric cancer subtypespecific biomarkers associated with prognosis
https://doi.org/10.18632/oncotarget.7411 Chae Hwa Kwon, Hye Ji Park, Yu Ri Choi, Ahrong Kim, Hye Won Kim, Jin Hwa Choi, Chung Su Hwang, So Jung Lee, Chang In Choi, Tae Yong Jeon, Dae Hwan Kim, Gwang Ha Kim, and Do Youn Park
21454-21468

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Mitochondrial stress controls the radiosensitivity of the oxygen effect: Implications for radiotherapy	Mitochondrial stress controls the radiosensitivity of the oxygen effect: Implications for radiotherapy
https://doi.org/10.18632/oncotarget.7412 Richard B. Richardson, and Mary-Ellen Harper
21469-21483

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1 3βDglucan assay for diagnosing invasive fungal infections in critically ill patients with hematological malignancies	1 3βDglucan assay for diagnosing invasive fungal infections in critically ill patients with hematological malignancies
https://doi.org/10.18632/oncotarget.7471 Elie Azoulay, Nicolas Guigue, Michael Darmon, Djamel Mokart, Virginie Lemiale, Achille Kouatchet, Julien Mayaux, François Vincent, Martine Nyunga, Fabrice Bruneel, Antoine Rabbat, Stéphane Bretagne, Christine Lebert, Anne-Pascale Meert, Dominique Benoit, and Frédéric Pene
21484-21495

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Overcoming resistance of targeted EGFR monotherapy by inhibition of STAT3 escape pathway in soft tissue sarcoma	Overcoming resistance of targeted EGFR monotherapy by inhibition of STAT3 escape pathway in soft tissue sarcoma
https://doi.org/10.18632/oncotarget.7452 Xiaochun Wang, David Goldstein, Philip J. Crowe, Mark Yang, Kerryn Garrett, Nikolajs Zeps, and Jia-Lin Yang
21496-21509

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HsamiR329 exerts tumor suppressor function through downregulation of MET in nonsmall cell lung cancer	HsamiR329 exerts tumor suppressor function through downregulation of MET in nonsmall cell lung cancer
https://doi.org/10.18632/oncotarget.7517 Cheng-Cao Sun, Shu-Jun Li, Feng Zhang, Jing-Yu Pan, Liang Wang, Cui-Li Yang, Yong-Yong Xi, and De-Jia Li
21510-21526

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Downregulation of 26S proteasome catalytic activity promotes epithelialmesenchymal transition	Downregulation of 26S proteasome catalytic activity promotes epithelialmesenchymal transition
https://doi.org/10.18632/oncotarget.7596 Asoka Banno, Daniel A. Garcia, Eric D. van Baarsel, Patrick J. Metz, Kathleen Fisch, Christella E. Widjaja, Stephanie H. Kim, Justine Lopez, Aaron N. Chang, Paul P. Geurink, Bogdan I. Florea, Hermen S. Overkleeft, Huib Ovaa, Jack D. Bui, Jing Yang, and John T. Chang
21527-21541

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The roles of AKR1C1 and AKR1C2 in ethyl34dihydroxybenzoate induced esophageal squamous cell carcinoma cell death	The roles of AKR1C1 and AKR1C2 in ethyl34dihydroxybenzoate induced esophageal squamous cell carcinoma cell death
https://doi.org/10.18632/oncotarget.7775 Wei Li, Guixue Hou, Dianrong Zhou, Xiaomin Lou, Yang Xu, Siqi Liu, and Xiaohang Zhao
21542-21555

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Multiplatform molecular profiling of a large cohort of glioblastomas reveals potential therapeutic strategies	Multiplatform molecular profiling of a large cohort of glioblastomas reveals potential therapeutic strategies
https://doi.org/10.18632/oncotarget.7722 Joanne Xiu, David Piccioni, Tiffany Juarez, Sandeep C. Pingle, Jethro Hu, Jeremy Rudnick, Karen Fink, David B. Spetzler, Todd Maney, Anatole Ghazalpour, Ryan Bender, Zoran Gatalica, Sandeep Reddy, Nader Sanai, Ahmed Idbaih, Michael Glantz, and Santosh Kesari
21556-21569

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Retrospective analysis on the safety of 5759 times of bedside hyperthermic intraperitoneal or intrapleural chemotherapy HIPEC	Retrospective analysis on the safety of 5759 times of bedside hyperthermic intraperitoneal or intrapleural chemotherapy HIPEC
https://doi.org/10.18632/oncotarget.7622 Lili Liu, Ning Zhang, Jie Min, Haichuan Su, Hongmei Wang, Dongxu Chen, Li Sun, Hongwei Zhang, Wei Li, and Helong Zhang
21570-21578

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Identification of a six microRNA signature as a novel potential prognostic biomarker in patients with head and neck squamous cell carcinoma	Identification of a six microRNA signature as a novel potential prognostic biomarker in patients with head and neck squamous cell carcinoma
https://doi.org/10.18632/oncotarget.7781 Hao Shi, Jian Chen, Yuncheng Li, Guojun Li, Rong Zhong, Dandan Du, Ruiwei Meng, Weijia Kong, and Meixia Lu
21579-21590

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Evidence of intermetastatic heterogeneity for pathological response and genetic mutations within colorectal liver metastases following preoperative chemotherapy	Evidence of intermetastatic heterogeneity for pathological response and genetic mutations within colorectal liver metastases following preoperative chemotherapy
https://doi.org/10.18632/oncotarget.7809 Mylène Sebagh, Marc-Antoine Allard, Nelly Bosselut, Myriam Dao, Eric Vibert, Maïté Lewin, Antoinette Lemoine, Daniel Cherqui, René Adam, and Antonio Sa Cunha
21591-21600

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APIP an ERBB3binding partner stimulates erbB23 heterodimer formation to promote tumorigenesis	APIP an ERBB3binding partner stimulates erbB23 heterodimer formation to promote tumorigenesis
https://doi.org/10.18632/oncotarget.7802 Se-Hoon Hong, Won Jae Lee, Young Doo Kim, Hyunjoo Kim, Young-Jun Jeon, Bitna Lim, Dong-Hyung Cho, Won Do Heo, Doo-Hyun Yang, Chan-Young Kim, Han-Kwang Yang, Jin Kuk Yang, and Yong-Keun Jung
21601-21617

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The epigenetic modifier CHD5 functions as a novel tumor suppressor for renal cell carcinoma and is predominantly inactivated by promoter CpG methylation	The epigenetic modifier CHD5 functions as a novel tumor suppressor for renal cell carcinoma and is predominantly inactivated by promoter CpG methylation
https://doi.org/10.18632/oncotarget.7822 Zhenfang Du, Lili Li, Xin Huang, Jie Jin, Suming Huang, Qian Zhang, and Qian Tao
21618-21630

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High LEF1 expression predicts adverse prognosis in chronic lymphocytic leukemia and may be targeted by ethacrynic acid	High LEF1 expression predicts adverse prognosis in chronic lymphocytic leukemia and may be targeted by ethacrynic acid
https://doi.org/10.18632/oncotarget.7795 Wei Wu, Huayuan Zhu, Yuan Fu, Wenyi Shen, Kourong Miao, Min Hong, Wei Xu, Lei Fan, Ken H. Young, Peng Liu, and Jianyong Li
21631-21643

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Hepatic cancer stem cell marker granulinepithelin precursor and βcatenin expression associate with recurrence in hepatocellular carcinoma	Hepatic cancer stem cell marker granulinepithelin precursor and βcatenin expression associate with recurrence in hepatocellular carcinoma
https://doi.org/10.18632/oncotarget.7803 Phyllis F.Y. Cheung, Tan To Cheung, Chi Wai Yip, Linda W.C. Ng, Sze Wai Fung, Chung Mau Lo, Sheung Tat Fan, and Siu Tim Cheung
21644-21657

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Screening of candidate Gquadruplex ligands for the human cKIT promotorial region and their effects in multiple invitro models	Screening of candidate Gquadruplex ligands for the human cKIT promotorial region and their effects in multiple invitro models
https://doi.org/10.18632/oncotarget.7808 Eleonora Zorzan, Silvia Da Ros, Caterina Musetti, Lara Zorro Shahidian, Nuno Filipe Ramos Coelho, Federico Bonsembiante, Sébastien Létard, Maria Elena Gelain, Manlio Palumbo, Patrice Dubreuil, Mery Giantin, Claudia Sissi, and Mauro Dacasto
21658-21675

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Analysis of plasma microRNA expression profiles revealed different cancer susceptibility in healthy young adult smokers and middleaged smokers	Analysis of plasma microRNA expression profiles revealed different cancer susceptibility in healthy young adult smokers and middleaged smokers
https://doi.org/10.18632/oncotarget.7866 Bing Shi, Hongmin Gao, Tianyang Zhang, and Qinghua Cui
21676-21685

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Gene modules associated with breast cancer distant metastasisfree survival in the PAM50 molecular subtypes	Gene modules associated with breast cancer distant metastasisfree survival in the PAM50 molecular subtypes
https://doi.org/10.18632/oncotarget.7774 Rong Liu, Wei Zhang, Zhao-Qian Liu, and Hong-Hao Zhou
21686-21698

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The paradigmshifting idea and its practice: from traditional abortion Chinese medicine Murraya paniculata to safe and effective cancer metastatic chemopreventives	The paradigmshifting idea and its practice: from traditional abortion Chinese medicine Murraya paniculata to safe and effective cancer metastatic chemopreventives
https://doi.org/10.18632/oncotarget.7932 Zhou Jiang, Yaqiong Pang, Xiaobo Yu, Suxia Zhou, Jun Qian, Ning Zheng, Haiyan Dong, Qing Shi, Minliang Kuo, and Lee Jia
21699-21712

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Notch signalling drives bone marrow stromal cellmediated chemoresistance in acute myeloid leukemia	Notch signalling drives bone marrow stromal cellmediated chemoresistance in acute myeloid leukemia
https://doi.org/10.18632/oncotarget.7964 Paul Takam Kamga, Giulio Bassi, Adriana Cassaro, Martina Midolo, Mariano Di Trapani, Alessandro Gatti, Roberta Carusone, Federica Resci, Omar Perbellini, Michele Gottardi, Massimiliano Bonifacio, Armel Hervé Nwabo Kamdje, Achille Ambrosetti, and Mauro Krampera
21713-21727

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4EGI1 induces apoptosis and enhances radiotherapy sensitivity in nasopharyngeal carcinoma cells via DR5 induction on 4EBP1 dephosphorylation	4EGI1 induces apoptosis and enhances radiotherapy sensitivity in nasopharyngeal carcinoma cells via DR5 induction on 4EBP1 dephosphorylation
https://doi.org/10.18632/oncotarget.7824 Weiyuan Wang, Jiao Li, Qiuyuan Wen, Jiadi Luo, Shuzhou Chu, Lingjiao Chen, Zhenzhen Qing, Guiyuan Xie, Lina Xu, Mohannad Ma Alnemah, Meirong Li, Songqing Fan, and Hongbo Zhang
21728-21741

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A prospective study on radiation doses to organs at risk OARs during intensitymodulated radiotherapy for nasopharyngeal carcinoma patients	A prospective study on radiation doses to organs at risk OARs during intensitymodulated radiotherapy for nasopharyngeal carcinoma patients
https://doi.org/10.18632/oncotarget.7826 Ji-Jin Yao, Fo-Ping Chen, Guan-Qun Zhou, Wang-Jian Zhang, Lin Xu, Xiao-Ju Wang, Li Lin, Jun Ma, and Ying Sun
21742-21752

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Systematic review with network metaanalysis: statins and risk of hepatocellular carcinoma	Systematic review with network metaanalysis: statins and risk of hepatocellular carcinoma
https://doi.org/10.18632/oncotarget.7832 Yao-Yao Zhou, Gui-Qi Zhu, Yue Wang, Ji-Na Zheng, Lu-Yi Ruan, Zhang Cheng, Bin Hu, Shen-Wen Fu, and Ming-Hua Zheng
21753-21762

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Oncogene and therapeutic target analyses in atypical fibroxanthomas and pleomorphic dermal sarcomas	Oncogene and therapeutic target analyses in atypical fibroxanthomas and pleomorphic dermal sarcomas
https://doi.org/10.18632/oncotarget.7845 Doris Helbig, Michaela Angelika Ihle, Katharina Pütz, Iliana Tantcheva-Poor, Cornelia Mauch, Reinhard Büttner, and Alexander Quaas
21763-21774

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DSGOST inhibits tumor growth by blocking VEGF/VEGFR2activated angiogenesis	DSGOST inhibits tumor growth by blocking VEGF/VEGFR2activated angiogenesis
https://doi.org/10.18632/oncotarget.7982 Hyeong Sim Choi, Kangwook Lee, Min Kyoung Kim, Kang Min Lee, Yong Cheol Shin, Sung-Gook Cho, and Seong-Gyu Ko
21775-21785

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Pin1 is required for sustained B cell proliferation upon oncogenic activation of Myc	Pin1 is required for sustained B cell proliferation upon oncogenic activation of Myc
https://doi.org/10.18632/oncotarget.7846 Luana D’Artista, Andrea Bisso, Andrea Piontini, Mirko Doni, Alessandro Verrecchia, Theresia R. Kress, Marco J. Morelli, Giannino Del Sal, Bruno Amati, and Stefano Campaner
21786-21798

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Phosphatase of regenerating liver3 inhibits invasiveness and proliferation in nonsmall cell lung cancer by regulating the epithelialmesenchymal transition	Phosphatase of regenerating liver3 inhibits invasiveness and proliferation in nonsmall cell lung cancer by regulating the epithelialmesenchymal transition
https://doi.org/10.18632/oncotarget.7985 Sheng‑Yi Lin, Yue‑Xun Lee, Sung‑Liang Yu, Gee‑Chen Chang, and Jeremy J.W. Chen
21799-21811

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Insights from HuR biology point to potential improvement for secondline ovarian cancer therapy	Insights from HuR biology point to potential improvement for secondline ovarian cancer therapy
https://doi.org/10.18632/oncotarget.7840 Yu-Hung Huang, Weidan Peng, Narumi Furuuchi, James B. DuHadaway, Masaya Jimbo, Andrea Pirritano, Charles J. Dunton, Gary S. Daum, Benjamin E. Leiby, Jonathan R. Brody, and Janet A. Sawicki
21812-21824

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MicroRNA543 suppresses colorectal cancer growth and metastasis by targeting KRAS MTA1 and HMGA2	MicroRNA543 suppresses colorectal cancer growth and metastasis by targeting KRAS MTA1 and HMGA2
https://doi.org/10.18632/oncotarget.7989 Chuannan Fan, Yancheng Lin, Yubin Mao, Zhengjie Huang, Allan Yi Liu, Handong Ma, Donghong Yu, Alaiyi Maitikabili, Hongjun Xiao, Chuankai Zhang, Fan Liu, Qi Luo, and Gaoliang Ouyang
21825-21839

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Exome and deep sequencing of clinically aggressive neuroblastoma reveal somatic mutations that affect key pathways involved in cancer progression	Exome and deep sequencing of clinically aggressive neuroblastoma reveal somatic mutations that affect key pathways involved in cancer progression
https://doi.org/10.18632/oncotarget.8187 Vito Alessandro Lasorsa, Daniela Formicola, Piero Pignataro, Flora Cimmino, Francesco Maria Calabrese, Jaume Mora, Maria Rosaria Esposito, Marcella Pantile, Carlo Zanon, Marilena De Mariano, Luca Longo, Michael D. Hogarty, Carmen de Torres, Gian Paolo Tonini, Achille Iolascon, and Mario Capasso
21840-21852

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IL17A promotes migration and tumor killing capability of B cells in esophageal squamous cell carcinoma	IL17A promotes migration and tumor killing capability of B cells in esophageal squamous cell carcinoma
https://doi.org/10.18632/oncotarget.7869 Lin Lu, Chengyin Weng, Haibo Mao, Xisheng Fang, Xia Liu, Yong Wu, Xiaofei Cao, Baoxiu Li, Xiaojun Chen, Qinquan Gan, Jianchuan Xia, and Guolong Liu
21853-21864

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A direct quantification method for measuring plasma MicroRNAs identified potential biomarkers for detecting metastatic breast cancer	A direct quantification method for measuring plasma MicroRNAs identified potential biomarkers for detecting metastatic breast cancer
https://doi.org/10.18632/oncotarget.7990 Qian Zhao, Shengqiong Deng, Guangxue Wang, Cuicui Liu, Lingyu Meng, Shanshan Qiao, Lei Shen, Yue Zhang, Jinhui Lü, Wenshu Li, Yuzhen Zhang, Min Wang, Richard G. Pestell, Chunli Liang, and Zuoren Yu
21865-21874

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The antihypertensive drug hydralazine activates the intrinsic pathway of apoptosis and causes DNA damage in leukemic T cells	The antihypertensive drug hydralazine activates the intrinsic pathway of apoptosis and causes DNA damage in leukemic T cells
https://doi.org/10.18632/oncotarget.7871 María J. Ruiz-Magaña, Rocío Martínez-Aguilar, Estefanía Lucendo, Diana Campillo-Davo, Klaus Schulze-Osthoff, and Carmen Ruiz-Ruiz
21875-21886

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EVI1 promotes cell proliferation in HBxinduced hepatocarcinogenesis as a critical transcription factor regulating lncRNAs	EVI1 promotes cell proliferation in HBxinduced hepatocarcinogenesis as a critical transcription factor regulating lncRNAs
https://doi.org/10.18632/oncotarget.7993 Jin-feng Huang, Yue Wang, Feng Liu, Yin Liu, Chen-xi Zhao, Ying-jun Guo, and Shu-han Sun
21887-21899

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C/EBP homologous protein CHOP deficiency ameliorates renal fibrosis in unilateral ureteral obstructive kidney disease	C/EBP homologous protein CHOP deficiency ameliorates renal fibrosis in unilateral ureteral obstructive kidney disease
https://doi.org/10.18632/oncotarget.7870 Shing-Hwa Liu, Cheng-Tien Wu, Kuo-How Huang, Ching-Chia Wang, Siao-Syun Guan, Li-Ping Chen, and Chih-Kang Chiang
21900-21912

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Prognostic effect of pregnancy on young female patients with nasopharyngeal carcinoma: results from a matched cohort analysis	Prognostic effect of pregnancy on young female patients with nasopharyngeal carcinoma: results from a matched cohort analysis
https://doi.org/10.18632/oncotarget.8008 Lu Zhang, Huai Liu, Lin-Quan Tang, Qiu-Yan Chen, Shan-Shan Guo, Li-Ting Liu, Ling Guo, Hao-Yuan Mo, Chong Zhao, Xiang Guo, Ka-Jia Cao, Chao-Nan Qian, Mu-Sheng Zeng, Jian-Yong Shao, Ying Sun, Jun Ma, Ming-Huang Hong, and Hai-Qiang Mai
21913-21921

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Increased PTP1B expression and phosphatase activity in colorectal cancer results in a more invasive phenotype and worse patient outcome	Increased PTP1B expression and phosphatase activity in colorectal cancer results in a more invasive phenotype and worse patient outcome
https://doi.org/10.18632/oncotarget.7829 Elmer Hoekstra, Asha M. Das, Marloes Swets, Wanlu Cao, C. Janneke van der Woude, Marco J. Bruno, Maikel P. Peppelenbosch, Peter J.K. Kuppen, Timo L.M. ten Hagen, and Gwenny M. Fuhler
21922-21938

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prp19 facilitates invasion of hepatocellular carcinoma via p38 mitogenactivated protein kinase/Twist1 pathway	Prp19 facilitates invasion of hepatocellular carcinoma via p38 mitogenactivated protein kinase/Twist1 pathway
https://doi.org/10.18632/oncotarget.7877 Jie Yin, Lan Wang, Ji-Min Zhu, Qian Yu, Ru-Yi Xue, Ying Fang, Yi-An Zhang, Yan-Jie Chen, Tao-Tao Liu, Ling Dong, and Xi-Zhong Shen
21939-21951

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Melatonin inhibits TPAinduced oral cancer cell migration by suppressing matrix metalloproteinase9 activation through the histone acetylation	Melatonin inhibits TPAinduced oral cancer cell migration by suppressing matrix metalloproteinase9 activation through the histone acetylation
https://doi.org/10.18632/oncotarget.8009 Chia-Ming Yeh, Chiao-Wen Lin, Jia-Sin Yang, Wei-En Yang, Shih-Chi Su, and Shun-Fa Yang
21952-21967

Abstract  |  PDF  |  Full Text  |  How to cite

Integrinlinked kinase activity modulates the prometastatic behavior of ovarian cancer cells	Integrinlinked kinase activity modulates the prometastatic behavior of ovarian cancer cells
https://doi.org/10.18632/oncotarget.7880 Lana Bruney, Yueying Liu, Anne Grisoli, Matthew J. Ravosa, and M. Sharon Stack
21968-21981

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Nextgeneration sequencing for sensitive detection of BCRABL1 mutations relevant to tyrosine kinase inhibitor choice in imatinibresistant patients	Nextgeneration sequencing for sensitive detection of BCRABL1 mutations relevant to tyrosine kinase inhibitor choice in imatinibresistant patients
https://doi.org/10.18632/oncotarget.8010 Simona Soverini, Caterina De Benedittis, Katerina Machova Polakova, Jana Linhartova, Fausto Castagnetti, Gabriele Gugliotta, Cristina Papayannidis, Manuela Mancini, Hana Klamova, Marzia Salvucci, Monica Crugnola, Alessandra Iurlo, Francesco Albano, Domenico Russo, Gianantonio Rosti, Michele Cavo, Michele Baccarani, and Giovanni Martinelli
21982-21990

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Activation of hERG3 channel stimulates autophagy and promotes cellular senescence in melanoma	Activation of hERG3 channel stimulates autophagy and promotes cellular senescence in melanoma
https://doi.org/10.18632/oncotarget.7831 Mathew Perez-Neut, Lauren Haar, Vidhya Rao, Sreevidya Santha, Katherine Lansu, Basabi Rana, Walter K. Jones, and Saverio Gentile
21991-22004

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Activation of the IGF1R pathway potentially mediates acquired resistance to mutantselective 3rdgeneration EGF receptor tyrosine kinase inhibitors in advanced nonsmall cell lung cancer	Activation of the IGF1R pathway potentially mediates acquired resistance to mutantselective 3rdgeneration EGF receptor tyrosine kinase inhibitors in advanced nonsmall cell lung cancer
https://doi.org/10.18632/oncotarget.8013 Ji Hyun Park, Yun Jung Choi, Seon Ye Kim, Jung-Eun Lee, Ki Jung Sung, Sojung Park, Woo Sung Kim, Joon Seon Song, Chang-Min Choi, Young Hoon Sung, Jin Kyung Rho, and Jae Cheol Lee
22005-22015

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Overexpression of USP39 predicts poor prognosis and promotes tumorigenesis of prostate cancer via promoting EGFR mRNA maturation and transcription elongation	Overexpression of USP39 predicts poor prognosis and promotes tumorigenesis of prostate cancer via promoting EGFR mRNA maturation and transcription elongation
https://doi.org/10.18632/oncotarget.7882 Yi Huang, Xiu-Wu Pan, Lin Li, Lu Chen, Xi Liu, Jian-Lei Lu, Xiao-Mei Zhu, Hai Huang, Qi-Wei Yang, Jian-Qing Ye, Si-Shun Gan, Lin-Hui Wang, Yi Hong, Dan-Feng Xu, and Xin-Gang Cui
22016-22030

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Indepth analysis of secretome and Nglycosecretome of human hepatocellular carcinoma metastatic cell lines shed light on metastasis correlated proteins	Indepth analysis of secretome and Nglycosecretome of human hepatocellular carcinoma metastatic cell lines shed light on metastasis correlated proteins
https://doi.org/10.18632/oncotarget.8247 Xianyu Li, Jing Jiang, Xinyuan Zhao, Yan Zhao, Qichen Cao, Qing Zhao, Huanhuan Han, Jifeng Wang, Zixiang Yu, Bo Peng, Wantao Ying, and Xiaohong Qian
22031-22049

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Knockdown of Hdj2/DNAJA1 cochaperone results in an unexpected burst of tumorigenicity of C6 glioblastoma cells	Knockdown of Hdj2/DNAJA1 cochaperone results in an unexpected burst of tumorigenicity of C6 glioblastoma cells
https://doi.org/10.18632/oncotarget.7872 Darya A. Meshalkina, Maxim A. Shevtsov, Anatoliy V. Dobrodumov, Elena Y. Komarova, Irina V. Voronkina, Vladimir F. Lazarev, Boris A. Margulis, and Irina V. Guzhova
22050-22063

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Mutation based treatment recommendations from next generation sequencing data: a comparison of web tools	Mutation based treatment recommendations from next generation sequencing data: a comparison of web tools
https://doi.org/10.18632/oncotarget.8017 Jaymin M. Patel, Joshua Knopf, Eric Reiner, Veerle Bossuyt, Lianne Epstein, Michael DiGiovanna, Gina Chung, Andrea Silber, Tara Sanft, Erin Hofstatter, Sarah Mougalian, Maysa Abu-Khalaf, James Platt, Weiwei Shi, Peter Gershkovich, Christos Hatzis, and Lajos Pusztai
22064-22076

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The TGFβ pathway is activated by 5fluorouracil treatment in drug resistant colorectal carcinoma cells	The TGFβ pathway is activated by 5fluorouracil treatment in drug resistant colorectal carcinoma cells
https://doi.org/10.18632/oncotarget.7895 Gabriele Romano, Ludovica Santi, Maria Rosaria Bianco, Maria Rita Giuffrè, Mariateresa Pettinato, Cristina Bugarin, Cristina Garanzini, Leonilde Savarese, Silvia Leoni, Maria Grazia Cerrito, Biagio Eugenio Leone, Giuseppe Gaipa, Emanuela Grassilli, Michele Papa, Marialuisa Lavitrano, and Roberto Giovannoni
22077-22091

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR448 promotes glycolytic metabolism of gastric cancer by downregulating KDM2B	MiR448 promotes glycolytic metabolism of gastric cancer by downregulating KDM2B
https://doi.org/10.18632/oncotarget.8020 Xuehui Hong, Yang Xu, Xingfeng Qiu, Yuekun Zhu, Xing Feng, Zhijie Ding, Shifeng Zhang, Lifeng Zhong, Yifan Zhuang, Chen Su, Xinya Hong, and Jianchun Cai
22092-22102

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Mutations in histone modulators are associated with prolonged survival during azacitidine therapy	Mutations in histone modulators are associated with prolonged survival during azacitidine therapy
https://doi.org/10.18632/oncotarget.7899 Magnus Tobiasson, Donal P. McLornan, Mohsen Karimi, Marios Dimitriou, Monika Jansson, Asmaa Ben Azenkoud, Martin Jädersten, Greger Lindberg, Hani Abdulkadir, Austin Kulasekararaj, Johanna Ungerstedt, Andreas Lennartsson, Karl Ekwall, Ghulam J. Mufti, and Eva Hellström-Lindberg
22103-22115

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Chemical chaperon 4phenylbutyrate protects against the endoplasmic reticulum stressmediated renal fibrosis in vivo and in vitro	Chemical chaperon 4phenylbutyrate protects against the endoplasmic reticulum stressmediated renal fibrosis in vivo and in vitro
https://doi.org/10.18632/oncotarget.7904 Shing-Hwa Liu, Ching-Chin Yang, Ding-Cheng Chan, Cheng-Tien Wu, Li-Ping Chen, Jenq-Wen Huang, Kuan-Yu Hung, and Chih-Kang Chiang
22116-22127

Abstract  |  PDF  |  Full Text  |  How to cite

Identification of differential PI3K pathway target dependencies in Tcell acute lymphoblastic leukemia through a large cancer cell panel screen	Identification of differential PI3K pathway target dependencies in Tcell acute lymphoblastic leukemia through a large cancer cell panel screen
https://doi.org/10.18632/oncotarget.8031 James T. Lynch, Robert McEwen, Claire Crafter, Ultan McDermott, Mathew J. Garnett, Simon T. Barry, and Barry R. Davies
22128-22139

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Germline genetics of cancer of unknown primary CUP and its specific subtypes	Germline genetics of cancer of unknown primary CUP and its specific subtypes
https://doi.org/10.18632/oncotarget.7903 Kari Hemminki, Bowang Chen, Abhishek Kumar, Olle Melander, Jonas Manjer, Göran Hallmans, Ulrika Pettersson-Kymmer, Claes Ohlsson, Gunnar Folprecht, Harald Löffler, Alwin Krämer, and Asta Försti
22140-22149

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Mitochondrial ribosomal protein S182 is highly expressed in endometrial cancers along with free E2F1	Mitochondrial ribosomal protein S182 is highly expressed in endometrial cancers along with free E2F1
https://doi.org/10.18632/oncotarget.7905 Miriam Mints, Muhammad Mushtaq, Natalia Iurchenko, Larysa Kovalevska, Maria C. Stip, Daria Budnikova, Sonia Andersson, Ludmila Polischuk, Lubov Buchynska, and Elena Kashuba
22150-22158

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Long noncoding RNA H19 indicates a poor prognosis of colorectal cancer and promotes tumor growth by recruiting and binding to eIF4A3	Long noncoding RNA H19 indicates a poor prognosis of colorectal cancer and promotes tumor growth by recruiting and binding to eIF4A3
https://doi.org/10.18632/oncotarget.8063 Dong Han, Xu Gao, Meng Wang, Yu Qiao, Ya Xu, Jing Yang, Nazhen Dong, Jun He, Qian Sun, Guixiang Lv, Changqing Xu, Ji Tao, and Ning Ma
22159-22173

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Modulation of chemokines in the tumor microenvironment enhances oncolytic virotherapy for colorectal cancer	Modulation of chemokines in the tumor microenvironment enhances oncolytic virotherapy for colorectal cancer
https://doi.org/10.18632/oncotarget.7907 Lily Francis, Zong Sheng Guo, Zuqiang Liu, Roshni Ravindranathan, Julie A. Urban, Magesh Sathaiah, Deepa Magge, Pawel Kalinski, and David L. Bartlett
22174-22185

Abstract  |  PDF  |  Full Text  |  How to cite

SMAD7 loci contribute to risk of hepatocellular carcinoma and clinicopathologic development among Chinese Han population	SMAD7 loci contribute to risk of hepatocellular carcinoma and clinicopathologic development among Chinese Han population
https://doi.org/10.18632/oncotarget.8065 Jiansong Ji, Min Xu, Zhongwei Zhao, Jianfei Tu, Jun Gao, Chenying Lu, Jingjing Song, Weiqian Chen, Minjiang Chen, Xiaoxi Fan, Xingyao Cheng, Xilin Lan, and Jie Li
22186-22192

Abstract  |  PDF  |  Full Text  |  How to cite

SH2 domaincontaining phosphatase 1 regulates pyruvate kinase M2 in hepatocellular carcinoma	SH2 domaincontaining phosphatase 1 regulates pyruvate kinase M2 in hepatocellular carcinoma
https://doi.org/10.18632/oncotarget.7923 Wei-Tien Tai, Man-Hsin Hung, Pei-Yi Chu, Yao-Li Chen, Li-Ju Chen, Ming-Hsien Tsai, Min-Husan Chen, Chung-Wai Shiau, Yin-Pin Boo, and Kuen- Feng Chen
22193-22205

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Small ubiquitinrelated modifier 1 is involved in hepatocellular carcinoma progression via mediating p65 nuclear translocation	Small ubiquitinrelated modifier 1 is involved in hepatocellular carcinoma progression via mediating p65 nuclear translocation
https://doi.org/10.18632/oncotarget.8066 Jun Liu, Xiaofang Tao, Jin Zhang, Peng Wang, Manqi Sha, Yong Ma, Xiaoping Geng, Lijie Feng, Yujun Shen, Yifan Yu, Siying Wang, Shengyun Fang, and Yuxian Shen
22206-22218

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Key roles of necroptotic factors in promoting tumor growth	Key roles of necroptotic factors in promoting tumor growth
https://doi.org/10.18632/oncotarget.7924 Xinjian Liu, Min Zhou, Ling Mei, Jiaying Ruan, Qian Hu, Jing Peng, Hang Su, Hong Liao, Shanling Liu, WeiPing Liu, He Wang, Qian Huang, Fang Li, and Chuan-Yuan Li
22219-22233

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prognostic roles for fibroblast growth factor receptor family members in malignant peripheral nerve sheath tumor	Prognostic roles for fibroblast growth factor receptor family members in malignant peripheral nerve sheath tumor
https://doi.org/10.18632/oncotarget.8067 Wenya Zhou, Xiaoling Du, Fengju Song, Hong Zheng, Kexin Chen, Wei Zhang, and Jilong Yang
22234-22244

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Specificity protein Sp transcription factors Sp1 Sp3 and Sp4 are nononcogene addiction genes in cancer cells	Specificity protein Sp transcription factors Sp1 Sp3 and Sp4 are nononcogene addiction genes in cancer cells
https://doi.org/10.18632/oncotarget.7925 Erik Hedrick, Yating Cheng, Un-Ho Jin, Kyounghyun Kim, and Stephen Safe
22245-22256

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Mutations of KRAS/NRAS/BRAF predict cetuximab resistance in metastatic colorectal cancer patients	Mutations of KRAS/NRAS/BRAF predict cetuximab resistance in metastatic colorectal cancer patients
https://doi.org/10.18632/oncotarget.8076 Hung-Chih Hsu, Tan Kien Thiam, Yen-Jung Lu, Chien Yuh Yeh, Wen-Sy Tsai, Jeng Fu You, Hsin Yuan Hung, Chi-Neu Tsai, An Hsu, Hua-Chien Chen, Shu-Jen Chen, and Tsai-Sheng Yang
22257-22270

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Systematic metaanalyses of genespecific genetic association studies in prostate cancer	Systematic metaanalyses of genespecific genetic association studies in prostate cancer
https://doi.org/10.18632/oncotarget.7926 Qiang Hao, Dong Wei, Yaoguang Zhang, Xin Chen, Fan Yang, Ze Yang, Xiaoquan Zhu, and Jianye Wang
22271-22284

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

AR42 induces apoptosis in human hepatocellular carcinoma cells via HDAC5 inhibition	AR42 induces apoptosis in human hepatocellular carcinoma cells via HDAC5 inhibition
https://doi.org/10.18632/oncotarget.8077 Mingming Zhang, Yida Pan, Robert G. Dorfman, Zhaogui Chen, Fuchen Liu, Qian Zhou, Shan Huang, Jun Zhang, Dongqin Yang, and Jie Liu
22285-22294

Abstract  |  PDF  |  Full Text  |  How to cite

Exploring the role of sphingolipid machinery during the epithelial to mesenchymal transition program using an integrative approach	Exploring the role of sphingolipid machinery during the epithelial to mesenchymal transition program using an integrative approach
https://doi.org/10.18632/oncotarget.7947 Anastasia Meshcheryakova, Martin Svoboda, Ammar Tahir, Harald C. Köfeler, Alexander Triebl, Felicitas Mungenast, Georg Heinze, Christopher Gerner, Philip Zimmermann, Markus Jaritz, and Diana Mechtcheriakova
22295-22323

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

To treat or not to treat: metabolomics reveals biomarkers for treatment indication in chronic lymphocytic leukaemia patients	To treat or not to treat: metabolomics reveals biomarkers for treatment indication in chronic lymphocytic leukaemia patients
https://doi.org/10.18632/oncotarget.8078 Jaroslaw Piszcz, Emily G. Armitage, Alessia Ferrarini, Francisco J. Rupérez, Agnieszka Kulczynska, Lukasz Bolkun, Janusz Kloczko, Adam Kretowski, Alina Urbanowicz, Michal Ciborowski, and Coral Barbas
22324-22338

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miR101 targeting ZFX suppresses tumor proliferation and metastasis by regulating the MAPK/Erk and Smad pathways in gallbladder carcinoma	miR101 targeting ZFX suppresses tumor proliferation and metastasis by regulating the MAPK/Erk and Smad pathways in gallbladder carcinoma
https://doi.org/10.18632/oncotarget.7970 Run-Fa Bao, Yi-Jun Shu, Yun-Ping Hu, Xu-An Wang, Fei Zhang, Hai-Bin Liang, Yuan-Yuan Ye, Huai-Feng Li, Shan-Shan Xiang, Hao Weng, Yang Cao, Xiang-Song Wu, Mao-Lan Li, Wen-guang Wu, Yi-Jian Zhang, Lin Jiang, Qian Dong, and Ying-Bin Liu
22339-22354

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Noninvasive bioluminescence imaging of the dynamics of sanguinarine induced apoptosis via activation of reactive oxygen species	Noninvasive bioluminescence imaging of the dynamics of sanguinarine induced apoptosis via activation of reactive oxygen species
https://doi.org/10.18632/oncotarget.7971 Yan Wang, Beilei Zhang, Wei Liu, Yunpeng Dai, Yaru Shi, Qi Zeng, and Fu Wang
22355-22367

Abstract  |  PDF  |  Full Text  |  How to cite

Systematic evaluation of cancer risk associated with rs2292832 in miR‑149 and rs895819 in miR‑27a: a comprehensive and updated meta‑analysis	Systematic evaluation of cancer risk associated with rs2292832 in miR‑149 and rs895819 in miR‑27a: a comprehensive and updated meta‑analysis
https://doi.org/10.18632/oncotarget.8082 Yajing Feng, Fujiao Duan, Chunhua Song, Xia Zhao, Liping Dai, and Shuli Cui
22368-22384

Abstract  |  PDF  |  Full Text  |  How to cite

Reduced cytosolic carboxypeptidase 6 CCP6 level leads to accumulation of serum polyglutamylated DNAJC7 protein: A potential biomarker for renal cell carcinoma early detection	Reduced cytosolic carboxypeptidase 6 CCP6 level leads to accumulation of serum polyglutamylated DNAJC7 protein: A potential biomarker for renal cell carcinoma early detection
https://doi.org/10.18632/oncotarget.8107 Chong Li, Jihan Wang, Junfeng Hao, Baijun Dong, Yi Li, Xiaoxiao Zhu, Juan Ding, Shuangchun Ren, Heping Zhao, Song Wu, Yong Tian, and Guo-Qing Wang
22385-22396

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Serum Helicobacter pylori FliD antibody and the risk of gastric cancer	Serum Helicobacter pylori FliD antibody and the risk of gastric cancer
https://doi.org/10.18632/oncotarget.7981 Hailin Li, Bing Zhang, Xiaomeng Hu, Yingzi Dong, Qing Fan, Fang Guo, Xiyun Ren, Haibo Zhou, Wenjing Tian, and Yashuang Zhao
22397-22408

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

In vitro and in vivo antitumor activity of CoQ0 against melanoma cells: inhibition of metastasis and induction of cellcycle arrest and apoptosis through modulation of Wnt/βcatenin signaling pathways	In vitro and in vivo antitumor activity of CoQ0 against melanoma cells: inhibition of metastasis and induction of cellcycle arrest and apoptosis through modulation of Wnt/βcatenin signaling pathways
https://doi.org/10.18632/oncotarget.7983 You-Cheng Hseu, Varadharajan Thiyagarajan, Hsiao-Tung Tsou, Kai-Yuan Lin, Hui-Jye Chen, Chung-Ming Lin, Jiuun-Wang Liao, and Hsin-Ling Yang
22409-22426

Abstract  |  PDF  |  Full Text  |  How to cite

Short and longterm outcomes in oncohematological patients admitted to the intensive care unit with classic factors of poor prognosis	Short and longterm outcomes in oncohematological patients admitted to the intensive care unit with classic factors of poor prognosis
https://doi.org/10.18632/oncotarget.7986 Etienne Faucher, Martin Cour, Vincent Jahandiez, Adeline Grateau, Thomas Baudry, Romain Hernu, Marie Simon, Jean-michel Robert, Mauricette Michallet, and Laurent Argaud
22427-22438

Abstract  |  PDF  |  Full Text  |  How to cite

Distinguishing epigenetic features of preneoplastic testis tissues adjacent to seminomas and nonseminomas	Distinguishing epigenetic features of preneoplastic testis tissues adjacent to seminomas and nonseminomas
https://doi.org/10.18632/oncotarget.7074 Ildar V. Gainetdinov, Sofia A. Kondratieva, Yulia V. Skvortsova, Marina V. Zinovyeva, Elena A. Stukacheva, Alexey Klimov, Alexey A. Tryakin, and Tatyana L. Azhikina
22439-22447

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ChIPonchip analysis of thyroid hormoneregulated genes and their physiological significance	ChIPonchip analysis of thyroid hormoneregulated genes and their physiological significance
https://doi.org/10.18632/oncotarget.7988 I-Hsiao Chung, Hsuan Liu, Yang-Hsiang Lin, Hsiang-Cheng Chi, Ya-Hui Huang, Chang-Ching Yang, Chau-Ting Yeh, Bertrand Chin-Ming Tan, and Kwang-Huei Lin
22448-22459

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Pantoprazole an FDAapproved protonpump inhibitor suppresses colorectal cancer growth by targeting Tcelloriginated protein kinase	Pantoprazole an FDAapproved protonpump inhibitor suppresses colorectal cancer growth by targeting Tcelloriginated protein kinase
https://doi.org/10.18632/oncotarget.7984 Xiaoyu Zeng, Lin Liu, Mengzhu Zheng, Huimin Sun, Juanjuan Xiao, Tao Lu, Guangqian Huang, Pianpian Chen, Jianmin Zhang, Feng Zhu, Hua Li, and Qiuhong Duan
22460-22473

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MG53 permeates through bloodbrain barrier to protect ischemic brain injury	MG53 permeates through bloodbrain barrier to protect ischemic brain injury
https://doi.org/10.18632/oncotarget.7965 Yonggang Yao, Bo Zhang, Hua Zhu, Haichang Li, Yu Han, Ken Chen, Zhen Wang, Jing Zeng, Yukai Liu, Xinquan Wang, Yu Li, Duofen He, Peihui Lin, Xinyu Zhou, Ki Ho Park, Zehua Bian, Zhishui Chen, Nianqiao Gong, Tao Tan, Jingsong Zhou, Meng Zhang, Jianjie Ma, and Chunyu Zeng
22474-22485

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Genetic variants in lncRNA SRA and risk of breast cancer	Genetic variants in lncRNA SRA and risk of breast cancer
https://doi.org/10.18632/oncotarget.7995 Rui Yan, Kaijuan Wang, Rui Peng, Shuaibing Wang, Jingjing Cao, Peng Wang, and Chunhua Song
22486-22496

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Impact of the number of resected lymph nodes on survival after preoperative radiotherapy for esophageal cancer	Impact of the number of resected lymph nodes on survival after preoperative radiotherapy for esophageal cancer
https://doi.org/10.18632/oncotarget.8113 San-Gang Wu, Zhao-Qiang Zhang, Wen-Ming Liu, Zhen-Yu He, Feng-Yan Li, Huan-Xin Lin, Jia-Yuan Sun, Hui Lin, and Qun Li
22497-22507

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Cancerassociated S100P protein binds and inactivates p53 permits therapyinduced senescence and supports chemoresistance	Cancerassociated S100P protein binds and inactivates p53 permits therapyinduced senescence and supports chemoresistance
https://doi.org/10.18632/oncotarget.7999 Adriana Gibadulinova, Michal Pastorek, Pavel Filipcik, Peter Radvak, Lucia Csaderova, Borivoj Vojtesek, and Silvia Pastorekova
22508-22522

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Is internal target volume accurate for dose evaluation in lung cancer stereotactic body radiotherapy	Is internal target volume accurate for dose evaluation in lung cancer stereotactic body radiotherapy
https://doi.org/10.18632/oncotarget.8000 Jiayuan Peng, Zhen Zhang, Jiazhou Wang, Jiang Xie, and Weigang Hu
22523-22530

Abstract  |  PDF  |  Full Text  |  How to cite

In vitro and in vivo effects of a recombinant antiPSMA immunotoxin in combination with docetaxel against prostate cancer	In vitro and in vivo effects of a recombinant antiPSMA immunotoxin in combination with docetaxel against prostate cancer
https://doi.org/10.18632/oncotarget.8001 Marta Michalska, Susanne Schultze-Seemann, Lioudmila Bogatyreva, Dieter Hauschke, Ulrich Wetterauer, and Philipp Wolf
22531-22542

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Determination of somatic oncogenic mutations linked to targetbased therapies using MassARRAY technology	Determination of somatic oncogenic mutations linked to targetbased therapies using MassARRAY technology
https://doi.org/10.18632/oncotarget.8002 Maider Ibarrola-Villava, Tania Fleitas, Marta J. Llorca-Cardeñosa, Cristina Mongort, Elisa Alonso, Samuel Navarro, Octavio Burgues, Ana Vivancos, Juan Miguel Cejalvo, José Alejandro Perez-Fidalgo, Susana Roselló, Gloria Ribas, and Andrés Cervantes
22543-22555

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Heparanase 2 expression inversely correlates with bladder carcinoma grade and stage	Heparanase 2 expression inversely correlates with bladder carcinoma grade and stage
https://doi.org/10.18632/oncotarget.8003 Miriam Gross-Cohen, Sari Feld, Inna Naroditsky, Ofer Nativ, Neta Ilan, and Israel Vlodavsky
22556-22565

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Non‑invasive prostate cancer detection by measuring miRNA variants isomiRs in urine extracellular vesicles	Non‑invasive prostate cancer detection by measuring miRNA variants isomiRs in urine extracellular vesicles
https://doi.org/10.18632/oncotarget.8124 Danijela Koppers-Lalic, Michael Hackenberg, Renee de Menezes, Branislav Misovic, Magda Wachalska, Albert Geldof, Nicoletta Zini, Theo de Reijke, Thomas Wurdinger, Andre Vis, Jeroen van Moorselaar, Michiel Pegtel, and Irene Bijnsdorp
22566-22578

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Dualtargeting triplebody 33319 mediates selective lysis of biphenotypic CD19+ CD33+ leukemia cells	Dualtargeting triplebody 33319 mediates selective lysis of biphenotypic CD19+ CD33+ leukemia cells
https://doi.org/10.18632/oncotarget.8022 Claudia C. Roskopf, Todd A. Braciak, Nadja C. Fenn, Sebastian Kobold, Georg H. Fey, Karl-Peter Hopfner, and Fuat S. Oduncu
22579-22589

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Regulation of limited Nterminal proteolysis of APE1 in tumor via acetylation and its role in cell proliferation	Regulation of limited Nterminal proteolysis of APE1 in tumor via acetylation and its role in cell proliferation
https://doi.org/10.18632/oncotarget.8026 Kishor K. Bhakat, Shiladitya Sengupta, Victor F. Adeniyi, Shrabasti Roychoudhury, Somsubhra Nath, Larry J. Bellot, Dan Feng, Anil K. Mantha, Mala Sinha, Suimin Qiu, and Bruce A. Luxon
22590-22604

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Therapy of solid tumors using probiotic Symbioflor2 – restraints and potential	Therapy of solid tumors using probiotic Symbioflor2 – restraints and potential
https://doi.org/10.18632/oncotarget.8027 Dino Kocijancic, Sebastian Felgner, Michael Frahm, Ronja-Melinda Komoll, Aida Iljazovic, Vinay Pawar, Manfred Rohde, Ulrike Heise, Kurt Zimmermann, Florian Gunzer, Juliane Hammer, Katja Crull, Sara Leschner, and Siegfried Weiss
22605-22622

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Oridonin a novel lysine acetyltransferases inhibitor inhibits proliferation and induces apoptosis in gastric cancer cells through p53 and caspase3mediated mechanisms	Oridonin a novel lysine acetyltransferases inhibitor inhibits proliferation and induces apoptosis in gastric cancer cells through p53 and caspase3mediated mechanisms
https://doi.org/10.18632/oncotarget.8033 Min Shi, Xiao-Jie Lu, Juan Zhang, Hua Diao, Guangming Li, Ling Xu, Ting Wang, Jue Wei, Wenying Meng, Jia-Li Ma, Heguo Yu, and Yu-Gang Wang
22623-22631

Abstract  |  PDF  |  Full Text  |  How to cite

MicroRNArelated polymorphisms in apoptosis pathway genes are predictive of clinical outcome in patients with limited disease small cell lung cancer	MicroRNArelated polymorphisms in apoptosis pathway genes are predictive of clinical outcome in patients with limited disease small cell lung cancer
https://doi.org/10.18632/oncotarget.8134 Wei Jiang, Nan Bi, Wen-Jue Zhang, Li-Hong Wu, Li-Pin Liu, Yu Men, Jing-Bo Wang, Jun Liang, Zhou-Guang Hui, Zong-Mei Zhou, and Lu-Hua Wang
22632-22638

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Loss of TINCR expression promotes proliferation metastasis through activating EpCAM cleavage in colorectal cancer	Loss of TINCR expression promotes proliferation metastasis through activating EpCAM cleavage in colorectal cancer
https://doi.org/10.18632/oncotarget.8141 Zuo-yang Zhang, Yan-xia Lu, Zhe-ying Zhang, Ya-ya Chang, Lin Zheng, Li Yuan, Fan Zhang, Yu-han Hu, Wen-juan Zhang, and Xue-nong Li
22639-22649

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Hypoxiainducible factor 1 alpha is required for the tumourigenic and aggressive phenotype associated with Rab25 expression in ovarian cancer	Hypoxiainducible factor 1 alpha is required for the tumourigenic and aggressive phenotype associated with Rab25 expression in ovarian cancer
https://doi.org/10.18632/oncotarget.7998 Natividad Gomez-Roman, Neha Mohan Sahasrabudhe, Fiona McGregor, Anthony J. Chalmers, Jim Cassidy, and Jane Plumb
22650-22664

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Difference in characteristics and outcomes between medullary breast carcinoma and invasive ductal carcinoma: a population based study from SEER 18 database	Difference in characteristics and outcomes between medullary breast carcinoma and invasive ductal carcinoma: a population based study from SEER 18 database
https://doi.org/10.18632/oncotarget.8142 Xiao-Xiao Wang, Yi-Zhou Jiang, Xi-Yu Liu, Jun-Jing Li, Chuan-Gui Song, and Zhi-Ming Shao
22665-22673

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MicroRNA630 suppresses tumor metastasis through the TGFβ miR630Slug signaling pathway and correlates inversely with poor prognosis in hepatocellular carcinoma	MicroRNA630 suppresses tumor metastasis through the TGFβ miR630Slug signaling pathway and correlates inversely with poor prognosis in hepatocellular carcinoma
https://doi.org/10.18632/oncotarget.8047 Wei-xun Chen, Zhan-guo Zhang, Ze-yang Ding, Hui-fang Liang, Jia Song, Xiao-long Tan, Jing-jing Wu, Guang-zhen Li, Zhuo Zeng, Bi-xiang Zhang, and Xiao-ping Chen
22674-22686

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

DDX3 enhances oncogenic KRAS‑induced tumor invasion in colorectal cancer via the β‑catenin/ZEB1 axis	DDX3 enhances oncogenic KRAS‑induced tumor invasion in colorectal cancer via the β‑catenin/ZEB1 axis
https://doi.org/10.18632/oncotarget.8143 De‑Wei Wu, Po‑Lin Lin, Ya‑Wen Cheng, Chi‑Chou Huang, Lee Wang, and Huei Lee
22687-22699

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Challenges in detecting premalignant pancreatic lesions during acute pancreatitis using a serum microRNA assay: a study based on KrasG12D transgenic mice	Challenges in detecting premalignant pancreatic lesions during acute pancreatitis using a serum microRNA assay: a study based on KrasG12D transgenic mice
https://doi.org/10.18632/oncotarget.8148 Xiafei Hong, Jie Zhang, Qiao Wu, Wenze Wang, Adam Yongxin Ye, Wei Song, Hongmei Dai, Xianze Wang, Fan Wu, Lei You, Wenming Wu, and Yupei Zhao
22700-22710

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Radiation dose escalation by simultaneous modulated accelerated radiotherapy combined with chemotherapy for esophageal cancer: a phase II study	Radiation dose escalation by simultaneous modulated accelerated radiotherapy combined with chemotherapy for esophageal cancer: a phase II study
https://doi.org/10.18632/oncotarget.8050 Jianzhou Chen, Hong Guo, Tiantian Zhai, Daniel Chang, Zhijian Chen, Ruihong Huang, Wuzhe Zhang, Kun Lin, Longjia Guo, Mingzhen Zhou, Dongsheng Li, Derui Li, and Chuangzhen Chen
22711-22719

Abstract  |  PDF  |  Full Text  |  How to cite

A novel prognostic score model incorporating CDGSH iron sulfur domain2 CISD2 predicts risk of disease progression in laryngeal squamous cell carcinoma	A novel prognostic score model incorporating CDGSH iron sulfur domain2 CISD2 predicts risk of disease progression in laryngeal squamous cell carcinoma
https://doi.org/10.18632/oncotarget.8150 Lin Yang, Shaodong Hong, Yan Wang, Zhenyu He, Shaobo Liang, Haiyang Chen, Shasha He, Shu Wu, Libing Song, and Yong Chen
22720-22732

Abstract  |  PDF  |  Full Text  |  How to cite

Antitumor activity and inhibitory effects on cancer stem celllike properties of Adenoassociated virus AAV mediated Bmi1 interference driven by Bmi1 promoter for gastric cancer	Antitumor activity and inhibitory effects on cancer stem celllike properties of Adenoassociated virus AAV mediated Bmi1 interference driven by Bmi1 promoter for gastric cancer
https://doi.org/10.18632/oncotarget.8174 Xiaowei Zhang, Weijian Guo, Xiaofeng Wang, Xinyang Liu, Mingzhu Huang, Lu Gan, Yufan Cheng, and Jin Li
22733-22745

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Association of HMGCR polymorphism with lateonset Alzheimer′s disease in Han Chinese	Association of HMGCR polymorphism with lateonset Alzheimer′s disease in Han Chinese
https://doi.org/10.18632/oncotarget.8176 Xiao-Long Chang, Lin Tan, Meng-Shan Tan, Hui-Fu Wang, Chen-Chen Tan, Wei Zhang, Zhan-Jie Zheng, Ling-Li Kong, Zi-Xuan Wang, Teng Jiang, Jin-Tai Yu, and Lan Tan
22746-22751

Abstract  |  PDF  |  Full Text  |  How to cite

Epigenetic alterations leading to TMPRSS4 promoter hypomethylation and protein overexpression predict poor prognosis in squamous lung cancer patients	Epigenetic alterations leading to TMPRSS4 promoter hypomethylation and protein overexpression predict poor prognosis in squamous lung cancer patients
https://doi.org/10.18632/oncotarget.8045 Maria Villalba, Angel Diaz-Lagares, Miriam Redrado, Arrate L. de Aberasturi, Victor Segura, Maria Elena Bodegas, Maria J. Pajares, Ruben Pio, Javier Freire, Javier Gomez-Roman, Luis M. Montuenga, Manel Esteller, Juan Sandoval, and Alfonso Calvo
22752-22769

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

LMO1 gene polymorphisms contribute to decreased neuroblastoma susceptibility in a Southern Chinese population	LMO1 gene polymorphisms contribute to decreased neuroblastoma susceptibility in a Southern Chinese population
https://doi.org/10.18632/oncotarget.8178 Jing He, Wei Zhong, Jixiao Zeng, Jinhong Zhu, Ruizhong Zhang, Fenghua Wang, Tianyou Yang, Yan Zou, and Huimin Xia
22770-22778

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ATP7B expression confers multidrug resistance through drug sequestration	ATP7B expression confers multidrug resistance through drug sequestration
https://doi.org/10.18632/oncotarget.8059 F M Moinuddin, Yoshinari Shinsato, Masaharu Komatsu, Ryoichi Mitsuo, Kentaro Minami, Masatatsu Yamamoto, Kohich Kawahara, Hirofumi Hirano, Kazunori Arita, and Tatsuhiko Furukawa
22779-22790

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Loss of miR449a in ERGassociated prostate cancer promotes the invasive phenotype by inducing SIRT1	Loss of miR449a in ERGassociated prostate cancer promotes the invasive phenotype by inducing SIRT1
https://doi.org/10.18632/oncotarget.8061 Parameet Kumar, Shashwat Sharad, Gyorgy Petrovics, Ahmed Mohamed, Albert Dobi, Taduru L. Sreenath, Shiv Srivastava, and Roopa Biswas
22791-22806

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

TAB3 OGlcNAcylation promotes metastasis of triple negative breast cancer	TAB3 OGlcNAcylation promotes metastasis of triple negative breast cancer
https://doi.org/10.18632/oncotarget.8182 Tao Tao, Zhixian He, Zhiming Shao, and Haojie Lu
22807-22818

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Features specific to retinal pigment epithelium cells derived from threedimensional human embryonic stem cell cultures — a new donor for cell therapy	Features specific to retinal pigment epithelium cells derived from threedimensional human embryonic stem cell cultures — a new donor for cell therapy
https://doi.org/10.18632/oncotarget.8185 Wei Wu, Yuxiao Zeng, Zhengya Li, Qiyou Li, Haiwei Xu, and Zheng Qin Yin
22819-22833

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

High leukocyte mtDNA content contributes to poor prognosis through ROSmediated immunosuppression in hepatocellular carcinoma patients	High leukocyte mtDNA content contributes to poor prognosis through ROSmediated immunosuppression in hepatocellular carcinoma patients
https://doi.org/10.18632/oncotarget.8071 Xianli He, Falin Qu, Feng Zhou, Xingchun Zhou, Yibing Chen, Xu Guo, Jibin Li, Qichao Huang, Yefa Yang, Zhuomin Lyu, Hongxin Zhang, and Jinliang Xing
22834-22845

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Automethylation of SUV39H2 an oncogenic histone lysine methyltransferase regulates its binding affinity to substrate proteins	Automethylation of SUV39H2 an oncogenic histone lysine methyltransferase regulates its binding affinity to substrate proteins
https://doi.org/10.18632/oncotarget.8072 Lianhua Piao, Makoto Nakakido, Takehiro Suzuki, Naoshi Dohmae, Yusuke Nakamura, and Ryuji Hamamoto
22846-22856

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Analysis of ultradeep targeted sequencing reveals mutation burden is associated with gender and clinical outcome in lung adenocarcinoma	Analysis of ultradeep targeted sequencing reveals mutation burden is associated with gender and clinical outcome in lung adenocarcinoma
https://doi.org/10.18632/oncotarget.8213 Dakai Xiao, Hui Pan, Fuqiang Li, Kui Wu, Xin Zhang, and Jianxing He
22857-22864

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

In silico analyses identify genesets associated with clinical outcome in ovarian cancer: role of mitotic kinases	In silico analyses identify genesets associated with clinical outcome in ovarian cancer: role of mitotic kinases
https://doi.org/10.18632/oncotarget.8118 Alberto Ocaña, Javier Pérez-Peña, Ana Alcaraz-Sanabria, Verónica Sánchez- Corrales, Cristina Nieto-Jiménez, Arnoud J. Templeton, Bostjan Seruga, Atanasio Pandiella, and Eitan Amir
22865-22872

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Blockage of autophagy pathway enhances Salmonella tumortargeting	Blockage of autophagy pathway enhances Salmonella tumortargeting
https://doi.org/10.18632/oncotarget.8251 Binghong Liu, Yanan Jiang, Tiangeng Dong, Ming Zhao, Jianfu Wu, Lihui Li, Yiwei Chu, Shangyang She, Hu Zhao, Robert M. Hoffman, and Lijun Jia
22873-22882

Abstract  |  PDF  |  Full Text  |  How to cite

Cellular apoptosis susceptibility CAS is linked to integrin β1 and required for tumor cell migration and invasion in hepatocellular carcinoma HCC	Cellular apoptosis susceptibility CAS is linked to integrin β1 and required for tumor cell migration and invasion in hepatocellular carcinoma HCC
https://doi.org/10.18632/oncotarget.8256 Juliane Winkler, Stephanie Roessler, Carsten Sticht, Amanda L. DiGuilio, Elisabeth Drucker, Kerstin Holzer, Eva Eiteneuer, Esther Herpel, Kai Breuhahn, Norbert Gretz, Peter Schirmacher, Alessandro Ori, and Stephan Singer
22883-22892

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Enhancing DPYSL3 gene expression via a promotertargeted small activating RNA approach suppresses cancer cell motility and metastasis	Enhancing DPYSL3 gene expression via a promotertargeted small activating RNA approach suppresses cancer cell motility and metastasis
https://doi.org/10.18632/oncotarget.8290 Changlin Li, Wencong Jiang, Qingting Hu, Long-cheng Li, Liang Dong, Ruibao Chen, Yinghong Zhang, Yuzhe Tang, J. Brantley Thrasher, Chang-Bai Liu, and Benyi Li
22893-22910

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinical Research Papers

Decreased MALL expression negatively impacts colorectal cancer patient survival	Decreased MALL expression negatively impacts colorectal cancer patient survival
https://doi.org/10.18632/oncotarget.8094 Xiaoliang Wang, Junwei Fan, Fudong Yu, Feifei Cui, Xing Sun, Lin Zhong, Dongwang Yan, Chongzhi Zhou, Guilong Deng, Bin Wang, Xiaosheng Qi, Shuyun Wang, Lei Qu, Biao Deng, Ming Pan, Jian Chen, Yupeng Wang, Guohe Song, Huamei Tang, Zongguang Zhou, and Zhihai Peng
22911-22927

Abstract  |  PDF  |  Full Text  |  How to cite

A phase I study of indoximod in patients with advanced malignancies	A phase I study of indoximod in patients with advanced malignancies
https://doi.org/10.18632/oncotarget.8216 Hatem H. Soliman, Susan E. Minton, Hyo Sook Han, Roohi Ismail-Khan, Anthony Neuger, Fatema Khambati, David Noyes, Richard Lush, Alberto A. Chiappori, John D. Roberts, Charles Link, Nicholas N. Vahanian, Mario Mautino, Howard Streicher, Daniel M. Sullivan, and Scott J. Antonia
22928-22938

Abstract  |  PDF  |  Full Text  |  How to cite

A scoring system based on artificial neural network for predicting 10year survival in stage II A colon cancer patients after radical surgery	A scoring system based on artificial neural network for predicting 10year survival in stage II A colon cancer patients after radical surgery
https://doi.org/10.18632/oncotarget.8217 Jian-Hong Peng, Yu-Jing Fang, Cai-Xia Li, Qing-Jian Ou, Wu Jiang, Shi-Xun Lu, Zhen-Hai Lu, Pei-Xing Li, Jing-Ping Yun, Rong-Xin Zhang, Zhi-Zhong Pan, and De-Sen Wan
22939-22947

Abstract  |  PDF  |  Full Text  |  How to cite

Body mass index and cholesterol level predict surgical outcome in patients with hepatocellular carcinoma in Taiwan a cohort study	Body mass index and cholesterol level predict surgical outcome in patients with hepatocellular carcinoma in Taiwan a cohort study
https://doi.org/10.18632/oncotarget.8312 Ya-Ling Lee, Wan-Chun Li, Tung-Hu Tsai, Hsin-Yu Chiang, and Chin-Tsung Ting
22948-22959

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Estimation of the risk of secondary malignancy arising from wholebreast irradiation: comparison of five radiotherapy modalities including TomoHDA	Estimation of the risk of secondary malignancy arising from wholebreast irradiation: comparison of five radiotherapy modalities including TomoHDA
https://doi.org/10.18632/oncotarget.8392 Eun Young Han, Nava Paudel, Jiwon Sung, Myonggeun Yoon, Weon Kuu Chung, and Dong Wook Kim
22960-22969

Abstract  |  PDF  |  Full Text  |  How to cite

Corrections

Correction: Tudor staphylococcal nuclease drives chemoresistance of nonsmall cell lung carcinoma cells by regulating S100A11	Correction: Tudor staphylococcal nuclease drives chemoresistance of nonsmall cell lung carcinoma cells by regulating S100A11
https://doi.org/10.18632/oncotarget.8805 Anna Zagryazhskaya, Olga Surova, Nadeem S. Akbar, Giulia Allavena, Katarina Gyuraszova, Irina B. Zborovskaya, Elena M. Tchevkina, and Boris Zhivotovsky
22970

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