Vol 7, No 16

Human platelets repurposed as vehicles for in vivo imaging of myeloma xenotransplants

Na⁺/H⁺ exchanger NHE1 regulation modulates metastatic potential and epithelial-mesenchymal transition of triple-negative breast cancer cells

A monoclonal antibody against the Wnt signaling inhibitor dickkopf-1 inhibits osteosarcoma metastasis in a preclinical model

Tissue repair genes: the TiRe database and its implication for skin wound healing

Activation of bitter taste receptors (tas2rs) relaxes detrusor smooth muscle and suppresses overactive bladder symptoms

Evaluation of p16/Ki-67 dual staining in detection of cervical precancer and cancers: a multicenter study in China

Ki-67 proliferation index but not mitotic thresholds integrates the molecular prognostic stratification of lower grade gliomas

Liang-Ge-San, a classic traditional Chinese medicine formula, protects against lipopolysaccharide-induced inflammation through cholinergic anti-inflammatory pathway

VEGF pathway targeting agents, vessel normalization and tumor drug uptake: from bench to bedside

Beyond evidence-based data: scientific rationale and tumor behavior to drive sequential and personalized therapeutic strategies for the treatment of metastatic renal cell carcinoma

Long-term prognostic implications and therapeutic target role of hexokinase II in patients with nasopharyngeal carcinoma

Imprinting defects at human 14q32 locus alters gene expression and is associated with the pathobiology of osteosarcoma

Metformin inhibits 17β-estradiol-induced epithelial-to-mesenchymal transition via βKlotho-related ERK1/2 signaling and AMPKα signaling in endometrial adenocarcinoma cells

Genetic and epigenetic background and protein expression profiles in relation to telomerase activation in medullary thyroid carcinoma

Survival benefit of surgery with radiotherapy vs surgery alone to patients with T2-3N0M0 stage esophageal adenocarcinoma

Molecular spectrum of TP53 mutations in plasma cell dyscrasias by next generation sequencing: an Italian cohort study and overview of the literature

EPH/ephrin profile and EPHB2 expression predicts patient survival in breast cancer

Nitrilase 1 modulates lung tumor progression in vitro and in vivo

A genetic study and meta-analysis of the genetic predisposition of prostate cancer in a Chinese population

Knockdown of Golgi phosphoprotein 2 inhibits hepatocellular carcinoma cell proliferation and motility

TNFSF10/TRAIL regulates human T4 effector memory lymphocyte radiosensitivity and predicts radiation-induced acute and subacute dermatitis

RHAMM splice variants confer radiosensitivity in human breast cancer cell lines

mir-329 restricts tumor growth by targeting grb2 in pancreatic cancer

PSMB8 and PBK as potential gastric cancer subtype-specific biomarkers associated with prognosis

Mitochondrial stress controls the radiosensitivity of the oxygen effect: Implications for radiotherapy

(1, 3)-β-D-glucan assay for diagnosing invasive fungal infections in critically ill patients with hematological malignancies

Overcoming resistance of targeted EGFR monotherapy by inhibition of STAT3 escape pathway in soft tissue sarcoma

Hsa-miR-329 exerts tumor suppressor function through down-regulation of MET in non-small cell lung cancer

Downregulation of 26S proteasome catalytic activity promotes epithelial-mesenchymal transition

The roles of AKR1C1 and AKR1C2 in ethyl-3,4-dihydroxybenzoate induced esophageal squamous cell carcinoma cell death

Multi-platform molecular profiling of a large cohort of glioblastomas reveals potential therapeutic strategies

Retrospective analysis on the safety of 5,759 times of bedside hyperthermic intra-peritoneal or intra-pleural chemotherapy (HIPEC)

Identification of a six microRNA signature as a novel potential prognostic biomarker in patients with head and neck squamous cell carcinoma

Evidence of intermetastatic heterogeneity for pathological response and genetic mutations within colorectal liver metastases following preoperative chemotherapy

APIP, an ERBB3-binding partner, stimulates erbB2-3 heterodimer formation to promote tumorigenesis

The epigenetic modifier CHD5 functions as a novel tumor suppressor for renal cell carcinoma and is predominantly inactivated by promoter CpG methylation

High LEF1 expression predicts adverse prognosis in chronic lymphocytic leukemia and may be targeted by ethacrynic acid

Hepatic cancer stem cell marker granulin-epithelin precursor and β-catenin expression associate with recurrence in hepatocellular carcinoma

Screening of candidate G-quadruplex ligands for the human c-KIT promotorial region and their effects in multiple in-vitro models

Analysis of plasma microRNA expression profiles revealed different cancer susceptibility in healthy young adult smokers and middle-aged smokers

Gene modules associated with breast cancer distant metastasis-free survival in the PAM50 molecular subtypes

The paradigm-shifting idea and its practice: from traditional abortion Chinese medicine Murraya paniculata to safe and effective cancer metastatic chemopreventives

Notch signalling drives bone marrow stromal cell-mediated chemoresistance in acute myeloid leukemia

4EGI-1 induces apoptosis and enhances radiotherapy sensitivity in nasopharyngeal carcinoma cells via DR5 induction on 4E-BP1 dephosphorylation

A prospective study on radiation doses to organs at risk (OARs) during intensity-modulated radiotherapy for nasopharyngeal carcinoma patients

Systematic review with network meta-analysis: statins and risk of hepatocellular carcinoma

Oncogene and therapeutic target analyses in atypical fibroxanthomas and pleomorphic dermal sarcomas

DSGOST inhibits tumor growth by blocking VEGF/VEGFR2-activated angiogenesis

Pin1 is required for sustained B cell proliferation upon oncogenic activation of Myc

Phosphatase of regenerating liver-3 inhibits invasiveness and proliferation in non-small cell lung cancer by regulating the epithelial-mesenchymal transition

Insights from HuR biology point to potential improvement for second-line ovarian cancer therapy

MicroRNA-543 suppresses colorectal cancer growth and metastasis by targeting KRAS, MTA1 and HMGA2

Exome and deep sequencing of clinically aggressive neuroblastoma reveal somatic mutations that affect key pathways involved in cancer progression

IL-17A promotes migration and tumor killing capability of B cells in esophageal squamous cell carcinoma

A direct quantification method for measuring plasma MicroRNAs identified potential biomarkers for detecting metastatic breast cancer

The antihypertensive drug hydralazine activates the intrinsic pathway of apoptosis and causes DNA damage in leukemic T cells

EVI1 promotes cell proliferation in HBx-induced hepatocarcinogenesis as a critical transcription factor regulating lncRNAs

C/EBP homologous protein (CHOP) deficiency ameliorates renal fibrosis in unilateral ureteral obstructive kidney disease

Prognostic effect of pregnancy on young female patients with nasopharyngeal carcinoma: results from a matched cohort analysis

Increased PTP1B expression and phosphatase activity in colorectal cancer results in a more invasive phenotype and worse patient outcome

Prp19 facilitates invasion of hepatocellular carcinoma via p38 mitogen-activated protein kinase/Twist1 pathway

Melatonin inhibits TPA-induced oral cancer cell migration by suppressing matrix metalloproteinase-9 activation through the histone acetylation

Integrin-linked kinase activity modulates the pro-metastatic behavior of ovarian cancer cells

Next-generation sequencing for sensitive detection of BCR-ABL1 mutations relevant to tyrosine kinase inhibitor choice in imatinib-resistant patients

Activation of hERG3 channel stimulates autophagy and promotes cellular senescence in melanoma

Activation of the IGF1R pathway potentially mediates acquired resistance to mutant-selective 3rd-generation EGF receptor tyrosine kinase inhibitors in advanced non-small cell lung cancer

Overexpression of USP39 predicts poor prognosis and promotes tumorigenesis of prostate cancer via promoting EGFR mRNA maturation and transcription elongation

In-depth analysis of secretome and N-glycosecretome of human hepatocellular carcinoma metastatic cell lines shed light on metastasis correlated proteins

Knock-down of Hdj2/DNAJA1 co-chaperone results in an unexpected burst of tumorigenicity of C6 glioblastoma cells

Mutation based treatment recommendations from next generation sequencing data: a comparison of web tools

The TGF-β pathway is activated by 5-fluorouracil treatment in drug resistant colorectal carcinoma cells

MiR-448 promotes glycolytic metabolism of gastric cancer by downregulating KDM2B

Mutations in histone modulators are associated with prolonged survival during azacitidine therapy

Chemical chaperon 4-phenylbutyrate protects against the endoplasmic reticulum stress-mediated renal fibrosis in vivo and in vitro

Identification of differential PI3K pathway target dependencies in T-cell acute lymphoblastic leukemia through a large cancer cell panel screen

Germline genetics of cancer of unknown primary (CUP) and its specific subtypes

Mitochondrial ribosomal protein S18-2 is highly expressed in endometrial cancers along with free E2F1

Long noncoding RNA H19 indicates a poor prognosis of colorectal cancer and promotes tumor growth by recruiting and binding to eIF4A3

Modulation of chemokines in the tumor microenvironment enhances oncolytic virotherapy for colorectal cancer

SMAD7 loci contribute to risk of hepatocellular carcinoma and clinicopathologic development among Chinese Han population

SH2 domain-containing phosphatase 1 regulates pyruvate kinase M2 in hepatocellular carcinoma

Small ubiquitin-related modifier 1 is involved in hepatocellular carcinoma progression via mediating p65 nuclear translocation

Key roles of necroptotic factors in promoting tumor growth

Prognostic roles for fibroblast growth factor receptor family members in malignant peripheral nerve sheath tumor

Specificity protein (Sp) transcription factors Sp1, Sp3 and Sp4 are non-oncogene addiction genes in cancer cells

Mutations of KRAS/NRAS/BRAF predict cetuximab resistance in metastatic colorectal cancer patients

Systematic meta-analyses of gene-specific genetic association studies in prostate cancer

AR-42 induces apoptosis in human hepatocellular carcinoma cells via HDAC5 inhibition

Exploring the role of sphingolipid machinery during the epithelial to mesenchymal transition program using an integrative approach

To treat or not to treat: metabolomics reveals biomarkers for treatment indication in chronic lymphocytic leukaemia patients

miR-101 targeting ZFX suppresses tumor proliferation and metastasis by regulating the MAPK/Erk and Smad pathways in gallbladder carcinoma

Noninvasive bioluminescence imaging of the dynamics of sanguinarine induced apoptosis via activation of reactive oxygen species

Systematic evaluation of cancer risk associated with rs2292832 in miR‑149 and rs895819 in miR‑27a: a comprehensive and updated meta‑analysis

Reduced cytosolic carboxypeptidase 6 (CCP6) level leads to accumulation of serum polyglutamylated DNAJC7 protein: A potential biomarker for renal cell carcinoma early detection

Serum Helicobacter pylori FliD antibody and the risk of gastric cancer

In vitro and in vivo anti-tumor activity of CoQ₀ against melanoma cells: inhibition of metastasis and induction of cell-cycle arrest and apoptosis through modulation of Wnt/β-catenin signaling pathways

Short- and long-term outcomes in onco-hematological patients admitted to the intensive care unit with classic factors of poor prognosis

Distinguishing epigenetic features of preneoplastic testis tissues adjacent to seminomas and nonseminomas

ChIP-on-chip analysis of thyroid hormone-regulated genes and their physiological significance

Pantoprazole, an FDA-approved proton-pump inhibitor, suppresses colorectal cancer growth by targeting T-cell-originated protein kinase

MG53 permeates through blood-brain barrier to protect ischemic brain injury

Genetic variants in lncRNA SRA and risk of breast cancer

Impact of the number of resected lymph nodes on survival after preoperative radiotherapy for esophageal cancer

Cancer-associated S100P protein binds and inactivates p53, permits therapy-induced senescence and supports chemoresistance

Is internal target volume accurate for dose evaluation in lung cancer stereotactic body radiotherapy?

In vitro and in vivo effects of a recombinant anti-PSMA immunotoxin in combination with docetaxel against prostate cancer

Determination of somatic oncogenic mutations linked to target-based therapies using MassARRAY technology

Heparanase 2 expression inversely correlates with bladder carcinoma grade and stage

Non‑invasive prostate cancer detection by measuring miRNA variants (isomiRs) in urine extracellular vesicles

Dual-targeting triplebody 33-3-19 mediates selective lysis of biphenotypic CD19⁺ CD33⁺ leukemia cells

Regulation of limited N-terminal proteolysis of APE1 in tumor via acetylation and its role in cell proliferation

Therapy of solid tumors using probiotic Symbioflor-2 – restraints and potential

Oridonin, a novel lysine acetyltransferases inhibitor, inhibits proliferation and induces apoptosis in gastric cancer cells through p53- and caspase-3-mediated mechanisms

MicroRNA-related polymorphisms in apoptosis pathway genes are predictive of clinical outcome in patients with limited disease small cell lung cancer

Loss of TINCR expression promotes proliferation, metastasis through activating EpCAM cleavage in colorectal cancer

Hypoxia-inducible factor 1 alpha is required for the tumourigenic and aggressive phenotype associated with Rab25 expression in ovarian cancer

Difference in characteristics and outcomes between medullary breast carcinoma and invasive ductal carcinoma: a population based study from SEER 18 database

MicroRNA-630 suppresses tumor metastasis through the TGF-β- miR-630-Slug signaling pathway and correlates inversely with poor prognosis in hepatocellular carcinoma

DDX3 enhances oncogenic KRAS‑induced tumor invasion in colorectal cancer via the β‑catenin/ZEB1 axis

Challenges in detecting pre-malignant pancreatic lesions during acute pancreatitis using a serum microRNA assay: a study based on Kras^G12D transgenic mice

Radiation dose escalation by simultaneous modulated accelerated radiotherapy combined with chemotherapy for esophageal cancer: a phase II study

A novel prognostic score model incorporating CDGSH iron sulfur domain2 (CISD2) predicts risk of disease progression in laryngeal squamous cell carcinoma

Antitumor activity and inhibitory effects on cancer stem cell-like properties of Adeno-associated virus (AAV) -mediated Bmi-1 interference driven by Bmi-1 promoter for gastric cancer

Association of HMGCR polymorphism with late-onset Alzheimer′s disease in Han Chinese

Epigenetic alterations leading to TMPRSS4 promoter hypomethylation and protein overexpression predict poor prognosis in squamous lung cancer patients

LMO1 gene polymorphisms contribute to decreased neuroblastoma susceptibility in a Southern Chinese population

ATP7B expression confers multidrug resistance through drug sequestration

Loss of miR-449a in ERG-associated prostate cancer promotes the invasive phenotype by inducing SIRT1

TAB3 O-GlcNAcylation promotes metastasis of triple negative breast cancer

Features specific to retinal pigment epithelium cells derived from three-dimensional human embryonic stem cell cultures — a new donor for cell therapy

High leukocyte mtDNA content contributes to poor prognosis through ROS-mediated immunosuppression in hepatocellular carcinoma patients

Automethylation of SUV39H2, an oncogenic histone lysine methyltransferase, regulates its binding affinity to substrate proteins

Analysis of ultra-deep targeted sequencing reveals mutation burden is associated with gender and clinical outcome in lung adenocarcinoma

In silico analyses identify gene-sets, associated with clinical outcome in ovarian cancer: role of mitotic kinases

Blockage of autophagy pathway enhances Salmonella tumor-targeting

Cellular apoptosis susceptibility (CAS) is linked to integrin β1 and required for tumor cell migration and invasion in hepatocellular carcinoma (HCC)

Enhancing DPYSL3 gene expression via a promoter-targeted small activating RNA approach suppresses cancer cell motility and metastasis

A phase I study of indoximod in patients with advanced malignancies

A scoring system based on artificial neural network for predicting 10-year survival in stage II A colon cancer patients after radical surgery

Body mass index and cholesterol level predict surgical outcome in patients with hepatocellular carcinoma in Taiwan - a cohort study

Estimation of the risk of secondary malignancy arising from whole-breast irradiation: comparison of five radiotherapy modalities, including TomoHDA