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About The Cover
The cover for issue 17 of Oncotarget features Figure 4B, "A comparison of the structural elements comprising human PHGDH, sPHGDH and PHGDH-93. Amino acids involved in hydrogen bond formation to the substrate (*) or cofactor NAD+ (*) are highlighted," from Unterlass, et al.
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Table of Contents
Research Papers: Pathology
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| The SRCfamily tyrosine kinase HCK shapes the landscape of SKAP2 interactome |
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https://doi.org/10.18632/oncotarget.24424
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| 13102-13115 |
Research Papers: Immunology
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| Correlation and agreement between eplet mismatches calculated using serological lowintermediate and high resolution molecular human leukocyte antigen typing methods |
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https://doi.org/10.18632/oncotarget.24349
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| 13116-13124 |
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| IL21 modulates memory and exhaustion phenotype of Tcells in a fatty acid oxidationdependent manner |
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https://doi.org/10.18632/oncotarget.24442
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| 13125-13138 |
Research Papers
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| Validating and enabling phosphoglycerate dehydrogenase PHGDH as a target for fragmentbased drug discovery in PHGDHamplified breast cancer |
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https://doi.org/10.18632/oncotarget.11487
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| 13139-13153 |
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| Targeting DYRK1B suppresses the proliferation and migration of liposarcoma cells |
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https://doi.org/10.18632/oncotarget.22743
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| 13154-13166 |
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| Phthalate exposure promotes chemotherapeutic drug resistance in colon cancer cells |
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https://doi.org/10.18632/oncotarget.23481
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| 13167-13180 |
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| Exploring the pathogenesis of canine epilepsy using a systems genetics method and implications for antiepilepsy drug discovery |
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https://doi.org/10.18632/oncotarget.23719
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| 13181-13192 |
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| EIF3Cenhanced exosome secretion promotes angiogenesis and tumorigenesis of human hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.24149
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| 13193-13205 |
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| Targeting of embryonic annexin A2 expressed on ovarian and breast cancer by the novel monoclonal antibody 2448 |
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https://doi.org/10.18632/oncotarget.24152
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| 13206-13221 |
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| The singlenucleotide polymorphisms in CHD5 affect the prognosis of patients with hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.23812
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| 13222-13230 |
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| Reprogrammed lipid metabolism in bladder cancer with cisplatin resistance |
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https://doi.org/10.18632/oncotarget.24229
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| 13231-13243 |
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| miR128 inhibits telomerase activity by targeting TERT mRNA |
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https://doi.org/10.18632/oncotarget.24284
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| 13244-13253 |
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| Mitochondrial fission as a driver of stemness in tumor cells: mDIVI1 inhibits mitochondrial function cell migration and cancer stem cell CSC signalling |
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https://doi.org/10.18632/oncotarget.24285
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| 13254-13275 |
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| Neutrophil extracellular traps promote lipopolysaccharideinduced airway inflammation and mucus hypersecretion in mice |
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https://doi.org/10.18632/oncotarget.24022
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| 13276-13286 |
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| Deficiency of proteinLisoaspartate Daspartate Omethyltransferase expression under endoplasmic reticulum stress promotes epithelial mesenchymal transition in lung adenocarcinoma |
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https://doi.org/10.18632/oncotarget.24324
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| 13287-13300 |
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| Systemic administration of a TLR7 agonist attenuates regulatory T cells by dendritic cell modification and overcomes resistance to PDL1 blockade therapy |
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https://doi.org/10.18632/oncotarget.24327
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| 13301-13312 |
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| CD151 promotes cell metastasis via activating TGFβ1/Smad signaling in renal cell carcinoma |
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https://doi.org/10.18632/oncotarget.24028
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| 13313-13323 |
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| Methotrexate sensitizes drugresistant metastatic melanoma cells to BRAF V600E inhibitors dabrafenib and encorafenib |
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https://doi.org/10.18632/oncotarget.24341
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| 13324-13336 |
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| Colorectal cancer cells require glycogen synthase kinase3β for sustaining mitosis via translocated promoter region TPRdynein interaction |
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https://doi.org/10.18632/oncotarget.24344
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| 13337-13352 |
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| The metalnonoate NiSalPipNONO inhibits in vitro tumor growth invasiveness and angiogenesis |
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https://doi.org/10.18632/oncotarget.24350
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| 13353-13365 |
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| Targeting angiogenesis in multiple myeloma by the VEGF and HGF blocking DARPin® protein MP0250: a preclinical study |
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https://doi.org/10.18632/oncotarget.24351
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| 13366-13381 |
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| Efficacy of different spinal nerve roots for neuromodulation of micturition reflex in rats |
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https://doi.org/10.18632/oncotarget.23950
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| 13382-13389 |
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| Amiodarone promotes cancer cell death through elevated truncated SRSF3 and downregulation of miR224 |
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https://doi.org/10.18632/oncotarget.24385
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| 13390-13406 |
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| Selenoprotein K deficiency inhibits melanoma by reducing calcium flux required for tumor growth and metastasis |
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https://doi.org/10.18632/oncotarget.24388
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| 13407-13422 |
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| The new allosteric inhibitor asciminib is susceptible to resistance mediated by ABCB1 and ABCG2 overexpression in vitro |
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https://doi.org/10.18632/oncotarget.24393
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| 13423-13437 |
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| Trifluridine/tipiracil overcomes the resistance of human gastric 5fluorouracilrefractory cells with high thymidylate synthase expression |
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https://doi.org/10.18632/oncotarget.24412
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| 13438-13450 |
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| Therapeutic significance of targeting survivin in cervical cancer and possibility of combination therapy with TRAIL |
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https://doi.org/10.18632/oncotarget.24413
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| 13451-13461 |
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| Gramnegative bacteria facilitate tumor progression through TLR4/IL33 pathway in patients with nonsmallcell lung cancer |
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https://doi.org/10.18632/oncotarget.24008
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| 13462-13473 |
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| CDK8/19 inhibition induces premature G1/S transition and ATRdependent cell death in prostate cancer cells |
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https://doi.org/10.18632/oncotarget.24414
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| 13474-13487 |
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| Effects of Cetuximab and Erlotinib on the behaviour of cancer stem cells in head and neck squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.24416
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| 13488-13500 |
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| Increased expression of MNK1b the spliced isoform of MNK1 predicts poor prognosis and is associated with triplenegative breast cancer |
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https://doi.org/10.18632/oncotarget.24417
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| 13501-13516 |
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| An open label trial of folate receptortargeted intraoperative molecular imaging to localize pulmonary squamous cell carcinomas |
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https://doi.org/10.18632/oncotarget.24399
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| 13517-13529 |
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| Quantitative mass spectrometry analysis reveals a panel of nine proteins as diagnostic markers for colon adenocarcinomas |
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https://doi.org/10.18632/oncotarget.24418
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| 13530-13544 |
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| CHL1 gene polymorphisms increase lung cancer susceptibility |
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https://doi.org/10.18632/oncotarget.24057
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| 13545-13550 |
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| Molecular profiling of ALDH1+ colorectal cancer stem cells reveals preferential activation of MAPK FAK and oxidative stress prosurvival signalling pathways |
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https://doi.org/10.18632/oncotarget.24420
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| 13551-13564 |
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| Human tripartite motif protein 52 is required for cell contextdependent proliferation |
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https://doi.org/10.18632/oncotarget.24422
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| 13565-13581 |
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| Leukocyte telomere length throughout the continuum of colorectal carcinogenesis |
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https://doi.org/10.18632/oncotarget.24431
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| 13582-13592 |
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| Adenosine A2A receptor ligand recognition and signaling is blocked by A2B receptors |
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https://doi.org/10.18632/oncotarget.24423
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| 13593-13611 |
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| Nuclear myosin/actinmotored contact between homologous chromosomes is initiated by ATM kinase and homologydirected repair proteins at doublestrand DNA breaks to suppress chromosome rearrangements |
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https://doi.org/10.18632/oncotarget.24434
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| 13612-13622 |
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| Prolonged in vivo expression and antitumor response of DNAbased antiHER2 antibodies |
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https://doi.org/10.18632/oncotarget.24426
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| 13623-13636 |
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| Protective role of integrinlinked kinase against oxidative stress and in maintenance of genomic integrity |
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https://doi.org/10.18632/oncotarget.24444
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| 13637-13651 |
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| Structural insights into drug development strategy targeting EGFR T790M/C797S |
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https://doi.org/10.18632/oncotarget.24113
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| 13652-13665 |
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| Persistent DNA strand breaks induce a CAFlike phenotype in normal fibroblasts |
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https://doi.org/10.18632/oncotarget.24446
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| 13666-13681 |
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| Correlation of MET gene amplification and TP53 mutation with PDL1 expression in nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.24455
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| 13682-13693 |
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| Engineered T lymphocytes eliminate lung metastases in models of pancreatic cancer |
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https://doi.org/10.18632/oncotarget.24122
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| 13694-13705 |
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| Interassay precision of clonogenic assays for radiosensitivity in cancer cell line A549 |
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https://doi.org/10.18632/oncotarget.24448
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| 13706-13712 |
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| Computational modeling suggests impaired interactions between NKX25 and GATA4 in individuals carrying a novel pathogenic D16N NKX25 mutation |
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https://doi.org/10.18632/oncotarget.24459
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| 13713-13732 |
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| Characterization of brain tumor initiating cells isolated from an animal model of CNS primitive neuroectodermal tumors |
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https://doi.org/10.18632/oncotarget.24460
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| 13733-13747 |
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| Proline oxidase silencing induces prolinedependent prosurvival pathways in MCF7 cells |
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https://doi.org/10.18632/oncotarget.24466
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| 13748-13757 |
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| MicroRNA630 may confer favorable cisplatinbased chemotherapy and clinical outcomes in nonsmall cell lung cancer by targeting Bcl2 |
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https://doi.org/10.18632/oncotarget.24474
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| 13758-13767 |
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| Artificial neural network approach to predict surgical site infection after freeflap reconstruction in patients receiving surgery for head and neck cancer |
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https://doi.org/10.18632/oncotarget.24468
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| 13768-13782 |
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| Cardiac glycoside bufalin blocks cancer cell growth by inhibition of Aurora A and Aurora B activation via PI3KAkt pathway |
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https://doi.org/10.18632/oncotarget.24475
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| 13783-13795 |
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| Merestinib LY2801653 inhibits neurotrophic receptor kinase NTRK and suppresses growth of NTRK fusion bearing tumors |
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https://doi.org/10.18632/oncotarget.24488
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| 13796-13806 |
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| Integrated DNA methylation analysis identifies topographical and tumoral biomarkers in pilocytic astrocytomas |
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https://doi.org/10.18632/oncotarget.24480
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| 13807-13821 |
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| Nucleolar stress enhances lytic reactivation of the Kaposi's sarcomaassociated herpesvirus |
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https://doi.org/10.18632/oncotarget.24497
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| 13822-13833 |
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| BclxL as a poor prognostic biomarker and predictor of response to adjuvant chemotherapy specifically in BRAFmutant stage II and III colon cancer |
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https://doi.org/10.18632/oncotarget.24481
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| 13834-13847 |
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| CTBP1 and metabolic syndrome induce an mRNA and miRNA expression profile critical for breast cancer progression and metastasis |
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https://doi.org/10.18632/oncotarget.24486
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| 13848-13858 |
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| Chemopreventive effects of angiotensin II receptor type 2 agonist on prostate carcinogenesis by the downregulation of the androgen receptor |
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https://doi.org/10.18632/oncotarget.24492
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| 13859-13869 |
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| A single digital droplet PCR assay to detect multiple KIT exon 11 mutations in tumor and plasma from patients with gastrointestinal stromal tumors |
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https://doi.org/10.18632/oncotarget.24493
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| 13870-13883 |
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| Structural considerations for functional antiEGFR × antiCD3 bispecific diabodies in light of domain order and binding affinity |
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https://doi.org/10.18632/oncotarget.24490
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| 13884-13893 |
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| Exosomal microRNA profiling to identify hypoxiarelated biomarkers in prostate cancer |
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https://doi.org/10.18632/oncotarget.24532
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| 13894-13910 |
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| Long noncoding RNA XIST as a potential prognostic biomarker in human cancers: a metaanalysis |
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https://doi.org/10.18632/oncotarget.23744
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| 13911-13919 |
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| Prognostic value of PDL1 in esophageal squamous cell carcinoma: a metaanalysis |
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https://doi.org/10.18632/oncotarget.23810
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| 13920-13933 |
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| Clinicopathologic and prognostic significance of Creactive protein/albumin ratio in patients with solid tumors: an updated systemic review and metaanalysis |
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https://doi.org/10.18632/oncotarget.24172
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| 13934-13947 |
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| MiR486 as an effective biomarker in cancer diagnosis and prognosis: a systematic review and metaanalysis |
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https://doi.org/10.18632/oncotarget.24189
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| 13948-13958 |
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| Association of body mass index with mortality and postoperative survival in renal cell cancer patients a metaanalysis |
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https://doi.org/10.18632/oncotarget.24210
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| 13959-13970 |
Clinical Research Papers
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| Combined value of red blood cell distribution width and global registry of acute coronary events risk score on predicting longterm major adverse cardiac events in STEMI patients undergoing primary PCI |
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https://doi.org/10.18632/oncotarget.24128
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| 13971-13980 |
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| Prevalence of nonsyndromic orofacial clefts: based on 15094978 Chinese perinatal infants |
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https://doi.org/10.18632/oncotarget.24238
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| 13981-13990 |
Reviews
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| The development of CAR design for tumor CART cell therapy |
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https://doi.org/10.18632/oncotarget.24179
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| 13991-14004 |
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| Impact of physical exercise in cancer survivors during and after antineoplastic treatments |
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https://doi.org/10.18632/oncotarget.24456
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| 14005-14034 |
Corrections
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| Correction: A RasGAP DAB2IP regulates lipid droplet homeostasis by serving as GAP toward RAB40C |
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https://doi.org/10.18632/oncotarget.24600
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| 14035-14035 |
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