Vol 7, No 21

Amino acid deprivation promotes intestinal homeostasis through autophagy

Metabolic vulnerabilities of MYC-induced cancer

Collecting duct carcinoma of the kidney is associated with CDKN2A deletion and SLC family gene up-regulation

Dual B- and T-cell de-immunization of recombinant immunotoxin targeting mesothelin with high cytotoxic activity

A Fhit-mimetic peptide suppresses annexin A4-mediated chemoresistance to paclitaxel in lung cancer cells

Hinokitiol protects primary neuron cells against prion peptide-induced toxicity via autophagy flux regulated by hypoxia inducing factor-1

Adaptive response to chronic mild ethanol stress involves ROS, sirtuins and changes in chromosome dosage in wine yeasts

The impact of adjuvant chemotherapy in older breast cancer patients on clinical and biological aging parameters

Human prion protein-induced autophagy flux governs neuron cell damage in primary neuron cells

Myelin injury induces axonal transport impairment but not AD-like pathology in the hippocampus of cuprizone-fed mice

Vitamin D receptor signaling improves Hutchinson-Gilford progeria syndrome cellular phenotypes

Effects of aging on the effectiveness of smoking cessation medication

RNA-Seq analysis reveals new evidence for inflammation-related changes in aged kidney

Crosstalk between insulin-like growth factor-1 and angiotensin-II in dopaminergic neurons and glial cells: role in neuroinflammation and aging

Inflammaging increases susceptibility to cigarette smoke-induced COPD

TAZ and YAP are frequently activated oncoproteins in sarcomas

Concomitant KIT/BRAF and PDGFRA/BRAF mutations are rare events in gastrointestinal stromal tumors

Differential expression of major histocompatibility complex class I in subtypes of breast cancer is associated with estrogen receptor and interferon signaling

Nebivolol, a β₁-adrenergic blocker, protects from peritoneal membrane damage induced during peritoneal dialysis

Hypergravity upregulates renal inducible nitric oxide synthase expression and nitric oxide production

Zfp207 is a Bub3 binding protein regulating meiotic chromosome alignment in mouse oocytes

Effect of tumor necrosis factor-α induced protein 8 like-2 on immune function of dendritic cells in mice following acute insults

Human mesenchymal stromal cell-secreted lactate induces M2-macrophage differentiation by metabolic reprogramming

Collaboration between tumor-specific CD4⁺ T cells and B cells in anti-cancer immunity

Both high and low levels of cellular Epstein-Barr virus DNA in blood identify failure after hematologic stem cell transplantation in conjunction with acute GVHD and type of conditioning

Clinical response to azacitidine therapy depends on microRNA-29c (miR-29c) expression in older acute myeloid leukemia (AML) patients

Impaired expression of DICER and some microRNAs in HBZ expressing cells from acute adult T-cell leukemia patients

Long noncoding RNA OR3A4 promotes metastasis and tumorigenicity in gastric cancer

Systematic large-scale meta-analysis identifies a panel of two mRNAs as blood biomarkers for colorectal cancer detection

Vinca alkaloid drugs promote stress-induced translational repression and stress granule formation

Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1)

SUMOylation of HP1α supports association with ncRNA to define responsiveness of breast cancer cells to chemotherapy

Hypermethylated in cancer 1(HIC1) suppresses non-small cell lung cancer progression by targeting interleukin-6/Stat3 pathway

Thin and thick primary cutaneous melanomas reveal distinct patterns of somatic copy number alterations

Abnormal lipid processing but normal long-term repopulation potential of myc-/- hepatocytes

Twist1 induces distinct cell states depending on TGFBR1-activation

Applying of pretreatment extent of disease system in patients with hepatocellular carcinoma after curative partial hepatectomy

Curcumin modulates chronic myelogenous leukemia exosomes composition and affects angiogenic phenotype via exosomal miR-21

Expression of MLL-AF4 or AF4-MLL fusions does not impact the efficiency of DNA damage repair

Comparative profiles of BRAF inhibitors: the paradox index as a predictor of clinical toxicity

MicroRNA-375/SEC23A as biomarkers of the in vitro efficacy of vandetanib

TRIM44 promotes proliferation and metastasis in non‑small cell lung cancer via mTOR signaling pathway

Bone marrow fibrosis in myelodysplastic syndromes: a prospective evaluation including mutational analysis

CK19 mRNA in blood can predict non-sentinel lymph node metastasis in breast cancer

Cisplatin induces stemness in ovarian cancer

CD30 on extracellular vesicles from malignant Hodgkin cells supports damaging of CD30 ligand-expressing bystander cells with Brentuximab-Vedotin, in vitro

MALT1 inhibitors prevent the development of DSS-induced experimental colitis in mice via inhibiting NF-κB and NLRP3 inflammasome activation

Low preoperative albumin-globulin score predicts favorable survival in esophageal squamous cell carcinoma

Gene identification for risk of relapse in stage I lung adenocarcinoma patients: a combined methodology of gene expression profiling and computational gene network analysis

Inflammasome-independent role of NLRP12 in suppressing colonic inflammation regulated by Blimp-1

Sexual dimorphism of liver metastasis by murine pancreatic neuroendocrine tumors is affected by expression of complement C5

CDX2 increases SLC7A7 expression and proliferation of pig intestinal epithelial cells

Epigenetic modification of miR-141 regulates SKA2 by an endogenous ‘sponge’ HOTAIR in glioma

Salinomycin induced ROS results in abortive autophagy and leads to regulated necrosis in glioblastoma

Systematic review with network meta-analysis: Comparative efficacy of oral nucleos(t)ide analogues for the prevention of chemotherapy-induced hepatitis B virus reactivation

Palmitoylated claudin7 captured in glycolipid-enriched membrane microdomains promotes metastasis via associated transmembrane and cytosolic molecules

Identification of lipid-phosphatidylserine (PS) as the target of unbiasedly selected cancer specific peptide-peptoid hybrid PPS1

PIK3CA amplification is associated with poor prognosis among patients with curatively resected esophageal squamous cell carcinoma

Downregulation of miRNA-638 promotes angiogenesis and growth of hepatocellular carcinoma by targeting VEGF

SRC kinase inhibition with saracatinib limits the development of osteolytic bone disease in multiple myeloma

miR-675-5p enhances tumorigenesis and metastasis of esophageal squamous cell carcinoma by targeting REPS2

Altered oncomodules underlie chromatin regulatory factors driver mutations

Novel diagnostic and prognostic classifiers for prostate cancer identified by genome-wide microRNA profiling

Prognostic significance of programmed death-1 and programmed death-ligand 1 expression in patients with esophageal squamous cell carcinoma

KCa3.1 channel inhibition sensitizes malignant gliomas to temozolomide treatment

Complications in multiple gestation pregnancy: A cross-sectional study of ten maternal-fetal medicine centers in China

A Toll-like receptor 2 agonist-fused antigen enhanced antitumor immunity by increasing antigen presentation and the CD8 memory T cells population

Integrin signaling via FAK-Src controls cytokinetic abscission by decelerating PLK1 degradation and subsequent recruitment of CEP55 at the midbody

Calcium influx-mediated translocation of m-calpain induces Ku80 cleavage and enhances the Ku80-related DNA repair pathway

Focal adhesion kinase and paxillin promote migration and adhesion to fibronectin by swine skeletal muscle satellite cells

N-acetylcysteine negatively regulates Notch3 and its malignant signaling

Tumour-associated circulating microparticles: A novel liquid biopsy tool for screening and therapy monitoring of colorectal carcinoma and other epithelial neoplasia

Potential role of exosome-associated microRNA panels and in vivo environment to predict drug resistance for patients with multiple myeloma

Increased reactive oxygen species and exhaustion of quiescent CD34-positive bone marrow cells may contribute to poor graft function after allotransplants

Long-term vemurafenib treatment drives inhibitor resistance through a spontaneous KRAS G12D mutation in a BRAF V600E papillary thyroid carcinoma model

Bone marrow mesenchymal stem cells participate in prostate carcinogenesis and promote growth of prostate cancer by cell fusion in vivo

Inhibition of SP1 by the mithramycin analog EC-8042 efficiently targets tumor initiating cells in sarcoma

Systemic and intratumoral balances between monocytes/macrophages and lymphocytes predict prognosis in hepatocellular carcinoma patients after surgery

USP14 is a predictor of recurrence in endometrial cancer and a molecular target for endometrial cancer treatment

PPMP, a novel tubulin-depolymerizing agent against esophageal cancer in patient-derived tumor xenografts

Krüppel-like factor 4 promotes human osteosarcoma growth and metastasis via regulating CRYAB expression

xCT increases tuberculosis susceptibility by regulating antimicrobial function and inflammation

Growth suppression by MYC inhibition in small cell lung cancer cells with TP53 and RB1 inactivation

MET expression during prostate cancer progression

The Arf-like GTPase Arl8b is essential for three-dimensional invasive growth of prostate cancer in vitro and xenograft formation and growth in vivo

Inhibition of myocyte-specific enhancer factor 2A improved diabetic cardiac fibrosis partially by regulating endothelial-to-mesenchymal transition

CYR61 (CCN1) is a metastatic biomarker of gastric cardia adenocarcinoma

Prognostic and predictive value of Ki-67 in triple-negative breast cancer

Cyclin D1 expression predicts postoperative distant metastasis and survival in resectable esophageal squamous cell carcinoma

Stabilin-1 is expressed in human breast cancer and supports tumor growth in mammary adenocarcinoma mouse model

EphB6 overexpression and Apc mutation together promote colorectal cancer

Overexpression of regulator of G protein signaling 11 promotes cell migration and associates with advanced stages and aggressiveness of lung adenocarcinoma

A comprehensive expression analysis of the MIA gene family in malignancies: MIA gene family members are novel, useful markers of esophageal, lung, and cervical squamous cell carcinoma

Estrogen-dependent downregulation of hypoxia-inducible factor (HIF)-2α in invasive breast cancer cells

Fractionation of Fab glycosylated immunoglobulin G with concanavalin A chromatography unveils new structural properties of the molecule

ZNF224, Krüppel like zinc finger protein, induces cell growth and apoptosis-resistance by down-regulation of p21 and p53 via miR-663a

Targeting ubiquitin-specific protease 22 suppresses growth and metastasis of anaplastic thyroid carcinoma

Relationship between insulin-like growth factor axis gene polymorphisms and clinical outcome in advanced gastric cancer patients treated with FOLFOX

Impact of capillary invasion on the prognosis of gastric adenocarcinoma patients: A retrospective cohort study

Triterpenoid herbal saponins enhance beneficial bacteria, decrease sulfate-reducing bacteria, modulate inflammatory intestinal microenvironment and exert cancer preventive effects in Apc^Min/+ mice

Inhibition of cancer cell epithelial mesenchymal transition by normal fibroblasts via production of 5-methoxytryptophan

Nuclear receptor 4A1 (NR4A1) as a drug target for treating rhabdomyosarcoma (RMS)

Correlational study on mitochondrial DNA mutations as potential risk factors in breast cancer

Mitochondrial transplantation attenuates hypoxic pulmonary vasoconstriction

The role of histamine in opening blood-tumor barrier

Chemolipiodolization with or without embolization in transcatheter arterial chemoembolization combined with radiofrequency ablation for hepatocellular carcinoma—propensity score matching analysis

TET1 inhibits gastric cancer growth and metastasis by PTEN demethylation and re-expression

Nesfatin-1/Nucleobindin-2 enhances cell migration, invasion, and epithelial-mesenchymal transition via LKB1/AMPK/TORC1/ZEB1 pathways in colon cancer

CYB5R1 links epithelial-mesenchymal transition and poor prognosis in colorectal cancer

Over-expression of the miR-483-3p overcomes the miR-145/TP53 pro-apoptotic loop in hepatocellular carcinoma

Association of nineteen polymorphisms from seven DNA repair genes and the risk for bladder cancer in Gansu province of China

Reduction in expression of the benign AR transcriptome is a hallmark of localised prostate cancer progression

IDH-1^R132H mutation status in diffuse glioma patients: implications for classification

The development and validation of a CT-based radiomics signature for the preoperative discrimination of stage I-II and stage III-IV colorectal cancer

Artemisinin and its derivatives can significantly inhibit lung tumorigenesis and tumor metastasis through Wnt/β-catenin signaling

Multiple analyses of large-scale genome-wide association study highlight new risk pathways in lumbar spine bone mineral density

NEDL2 regulates enteric nervous system and kidney development in its Nedd8 ligase activity-dependent manner

CTNNA1 hypermethylation, a frequent event in acute myeloid leukemia, is independently associated with an adverse outcome

Asclepiasterol, a novel C21 steroidal glycoside derived from Asclepias curassavica, reverses tumor multidrug resistance by down-regulating P-glycoprotein expression

Emblica officinalis extract downregulates pro-angiogenic molecules via upregulation of cellular and exosomal miR-375 in human ovarian cancer cells

The efficacy and safety of endostar combined with taxane-based regimens for HER-2-negative metastatic breast cancer patients

Validation of DAB2IP methylation and its relative significance in predicting outcome in renal cell carcinoma

CUL2 overexpression driven by CUL2/E2F1/miR-424 regulatory loop promotes HPV16 E7 induced cervical carcinogenesis

Mesothelin's minimal MUC16 binding moiety converts TR3 into a potent cancer therapeutic via hierarchical binding events at the plasma membrane

Wip1 phosphatase: between p53 and MAPK kinases pathways

Role of multifaceted regulators in cancer glucose metabolism and their clinical significance

FAK and paxillin, two potential targets in pancreatic cancer