Oncotarget

October 13, 2017

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About The Cover

The cover for issue 48 of Oncotarget features Figure 1, "BM-MSC transcriptome regulation by AML," from Jacamo, et al.

Table of Contents

Priority Research Papers

Tumor Trp53 status and genotype affect the bone marrow microenvironment in acute myeloid leukemia

Tumor Trp53 status and genotype affect the bone marrow microenvironment in acute myeloid leukemia

https://doi.org/10.18632/oncotarget.19042

Rodrigo Jacamo, R. Eric Davis, Xiaoyang Ling, Sonali Sonnylal, Zhiqiang Wang, Wencai Ma, Min Zhang, Peter Ruvolo, Vivian Ruvolo, Rui-Yu Wang, Teresa McQueen, Scott Lowe, Johannes Zuber, Steven M. Kornblau, Marina Konopleva,  and Michael Andreeff
83354-83369
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite  |  Podcast

IL2RG, identified as overexpressed by RNA-seq profiling of pancreatic intraepithelial neoplasia, mediates pancreatic cancer growth

IL2RG, identified as overexpressed by RNA-seq profiling of pancreatic intraepithelial neoplasia, mediates pancreatic cancer growth

https://doi.org/10.18632/oncotarget.19848

Michael Ayars, Eileen O’Sullivan, Anne Macgregor-Das, Koji Shindo, Haeryoung Kim, Michael Borges, Jun Yu, Ralph H. Hruban,  and Michael Goggins
83370-83383
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

MicroRNA-200, associated with metastatic breast cancer, promotes traits of mammary luminal progenitor cells

MicroRNA-200, associated with metastatic breast cancer, promotes traits of mammary luminal progenitor cells

https://doi.org/10.18632/oncotarget.20698

Lourdes Sánchez-Cid, Mònica Pons, Juan José Lozano, Nuria Rubio, Marta Guerra-Rebollo, Aroa Soriano, Laia Paris-Coderch, Miquel F. Segura, Raquel Fueyo, Judit Arguimbau, Erika Zodda, Raquel Bermudo, Immaculada Alonso, Xavier Caparrós, Marta Cascante, Arash Rafii, Yibin Kang, Marian Martínez-Balbás, Stephen J. Weiss, Jerónimo Blanco, Montserrat Muñoz, Pedro L. Fernández,  and Timothy M. Thomson
83384-83406
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Research Papers: Gerotarget (Focus on Aging)

Maternal high calorie diet induces mitochondrial dysfunction and senescence phenotype in subcutaneous fat of newborn mice

Maternal high calorie diet induces mitochondrial dysfunction and senescence phenotype in subcutaneous fat of newborn mice

https://doi.org/10.18632/oncotarget.19948

Daniele Lettieri-Barbato, Fabiana D’Angelo, Francesca Sciarretta, Giuseppe Tatulli, Flavia Tortolici, Maria Rosa Ciriolo,  and Katia Aquilano
83407-83418
Abstract  |  PDF  |  HTML  |  How to cite

Research Papers: Immunology

Mesenchymal stem cells inhibit RANK-RANKL interactions between osteoclasts and Th17 cells via osteoprotegerin activity

Mesenchymal stem cells inhibit RANK-RANKL interactions between osteoclasts and Th17 cells via osteoprotegerin activity

https://doi.org/10.18632/oncotarget.21379

Kyung-Ah Cho, Minhwa Park, Yu-Hee Kim, Kyung-Ha Ryu,  and So-Youn Woo
83419-83431
Abstract  |  PDF  |  HTML  |  How to cite

Research Papers

ERpS294 is a biomarker of ligand or mutational ERα activation and a breast cancer target for CDK2 inhibition

ERpS294 is a biomarker of ligand or mutational ERα activation and a breast cancer target for CDK2 inhibition

https://doi.org/10.18632/oncotarget.12735

Gary K. Scott, David Chu, Ravneet Kaur, Julia Malato, Daniel E. Rothschild, Katya Frazier, Serenella Eppenberger-Castori, Byron Hann, Ben Ho Park,  and Christopher C. Benz
83432-83445
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

A pilot study evaluating concordance between blood-based and patient-matched tumor molecular testing within pancreatic cancer patients participating in the Know Your Tumor (KYT) initiative

A pilot study evaluating concordance between blood-based and patient-matched tumor molecular testing within pancreatic cancer patients participating in the Know Your Tumor (KYT) initiative

https://doi.org/10.18632/oncotarget.13225

Michael J. Pishvaian, R. Joseph Bender, Lynn M. Matrisian, Lola Rahib, Andrew Hendifar, William A. Hoos, Sam Mikhail, Vincent Chung, Vincent Picozzi, Craig Heartwell, Kimberly Mason, Katelyn Varieur, Metasebia Aberra, Subha Madhavan, Emanuel Petricoin III,  and Jonathan R. Brody
83446-83456
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Disruption of STAT3-DNMT1 interaction by SH-I-14 induces re-expression of tumor suppressor genes and inhibits growth of triple-negative breast tumor

Disruption of STAT3-DNMT1 interaction by SH-I-14 induces re-expression of tumor suppressor genes and inhibits growth of triple-negative breast tumor

https://doi.org/10.18632/oncotarget.4054

Hyo Jin Kang, Yong Weon Yi, Shu-Jie Hou, Hee Jeong Kim, Yali Kong, Insoo Bae,  and Milton L. Brown
83457-83468
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

AKR7A3 suppresses tumorigenicity and chemoresistance in hepatocellular carcinoma through attenuation of ERK, c-Jun and NF-κB signaling pathways

AKR7A3 suppresses tumorigenicity and chemoresistance in hepatocellular carcinoma through attenuation of ERK, c-Jun and NF-κB signaling pathways

https://doi.org/10.18632/oncotarget.12726

Raymond Kwok Kei Chow, Sarah Tsz-Kwan Sin, Ming Liu, Yan Li, Tim Hon Man Chan, Yangyang Song, Leilei Chen, Dora Lai-Wan Kwong,  and Xin-Yuan Guan
83469-83479
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

TM4SF5 promotes metastatic behavior of cells in 3D extracellular matrix gels by reducing dependency on environmental cues

TM4SF5 promotes metastatic behavior of cells in 3D extracellular matrix gels by reducing dependency on environmental cues

https://doi.org/10.18632/oncotarget.17644

Dae-Geun Song, Gyu-Ho Lee, Seo Hee Nam, Jin-Gyu Cheong, Doyoung Jeong, Seo-Jin Lee, Cheol-Ho Pan, Jae Woo Jung, Hye-Jin Kim, Jihye Ryu, Ji Eon Kim, Somi Kim, Chang Yun Cho, Min-Kyung Kang, Kyung-Min Lee,  and Jung Weon Lee
83480-83494
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Granulysin expressed in a humanized mouse model induces apoptotic cell death and suppresses tumorigenicity

Granulysin expressed in a humanized mouse model induces apoptotic cell death and suppresses tumorigenicity

https://doi.org/10.18632/oncotarget.11473

Ya-Wen Hsiao, Tsung-Ching Lai, Yu-Hsiang Lin, Chia-Yi Su, Jih-Jong Lee, Albert Taiching Liao, Yuan-Feng Lin, Shu-Chen Hsieh, Alexander T.H. Wu,  and Michael Hsiao
83495-83508
Abstract  |  PDF  |  HTML  |  How to cite

Novel mechanisms for crotonaldehyde-induced lung edema

Novel mechanisms for crotonaldehyde-induced lung edema

https://doi.org/10.18632/oncotarget.17840

Yue Li, Jianjun Chang, Yong Cui, Runzhen Zhao, Yan Ding, Yapeng Hou, Zhiyu Zhou, Hong-Long Ji,  and Hongguang Nie
83509-83522
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Downregulation of miR-199a-5p promotes prostate adeno-carcinoma progression through loss of its inhibition of HIF-1α

Downregulation of miR-199a-5p promotes prostate adeno-carcinoma progression through loss of its inhibition of HIF-1α

https://doi.org/10.18632/oncotarget.18315

Jinjing Zhong, Rui Huang, Zhengzheng Su, Mengni Zhang, Miao Xu, Jing Gong, Ni Chen, Hao Zeng, Xueqin Chen,  and Qiao Zhou
83523-83538
Abstract  |  PDF  |  HTML  |  How to cite

An optimized HMGB1 expressed by recombinant rabies virus enhances immunogenicity through activation of dendritic cells in mice

An optimized HMGB1 expressed by recombinant rabies virus enhances immunogenicity through activation of dendritic cells in mice

https://doi.org/10.18632/oncotarget.18368

Zhao Wang, Qian Liang, Yajing Zhang, Jie Yang, Mingming Li, Kunlun Wang, Min Cui, Huanchun Chen, Zhen F. Fu, Ling Zhao,  and Ming Zhou
83539-83554
Abstract  |  PDF  |  HTML  |  How to cite

Comparison of the 7th and 8th editions of the American joint committee on cancer TNM classification for patients with stage III gastric cancer

Comparison of the 7th and 8th editions of the American joint committee on cancer TNM classification for patients with stage III gastric cancer

https://doi.org/10.18632/oncotarget.18375

Jun Lu, Chao-Hui Zheng, Long-Long Cao, Ping Li, Jian-Wei Xie, Jia-Bin Wang, Jian-Xian Lin, Qi-Yue Chen, Mi Lin, Ru-hong Tu,  and Chang-Ming Huang
83555-83562
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Association between MMP3 and TIMP3 polymorphisms and risk of osteoarthritis

Association between MMP3 and TIMP3 polymorphisms and risk of osteoarthritis

https://doi.org/10.18632/oncotarget.18745

Zhichao Tong, Yang Liu, Bo Chen, Liang Yan,  and Dingjun Hao
83563-83569
Abstract  |  PDF  |  HTML  |  How to cite

Longitudinal serum metabolomics evaluation of trastuzumab and everolimus combination as pre-operative treatment for HER-2 positive breast cancer patients

Longitudinal serum metabolomics evaluation of trastuzumab and everolimus combination as pre-operative treatment for HER-2 positive breast cancer patients

https://doi.org/10.18632/oncotarget.18784

Elodie Jobard, Olivier Trédan, Thomas Bachelot, Arnaud M. Vigneron, Céline Mahier Aït-Oukhatar, Monica Arnedos, Maria Rios, Jacques Bonneterre, Véronique Diéras, Marta Jimenez, Jean-Louis Merlin, Mario Campone,  and Bénédicte Elena-Herrmann
83570-83584
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

P-, but not E- or L-, selectin-mediated rolling adhesion persistence in hemodynamic flow diverges between metastatic and leukocytic cells

P-, but not E- or L-, selectin-mediated rolling adhesion persistence in hemodynamic flow diverges between metastatic and leukocytic cells

https://doi.org/10.18632/oncotarget.18786

Erin Elizabeth Edwards, Jaeho Oh, Ananyaveena Anilkumar, Katherine Gayle Birmingham,  and Susan Napier Thomas
83585-83601
Abstract  |  PDF  |  HTML  |  How to cite

Glycolytic reprogramming through PCK2 regulates tumor initiation of prostate cancer cells

Glycolytic reprogramming through PCK2 regulates tumor initiation of prostate cancer cells

https://doi.org/10.18632/oncotarget.18787

Jiangsha Zhao, Jieran Li, Teresa W. M. Fan,  and Steven X. Hou
83602-83618
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

The protective effects of carboxyhemoglobin during the resuscitation from hemorrhagic shock in rats

The protective effects of carboxyhemoglobin during the resuscitation from hemorrhagic shock in rats

https://doi.org/10.18632/oncotarget.18768

Hongyu Liu, Songyan Yu, Yaojun Peng, Xin Chang,  and Xinguang Yu
83619-83625
Abstract  |  PDF  |  HTML  |  How to cite

LRH-1 expression patterns in breast cancer tissues are associated with tumour aggressiveness

LRH-1 expression patterns in breast cancer tissues are associated with tumour aggressiveness

https://doi.org/10.18632/oncotarget.18886

Jia-Min B. Pang, Ramyar Molania, Ashwini Chand, Kevin Knower, Elena A. Takano, David J. Byrne, Thomas Mikeska, Ewan K.A. Millar, Cheok Soon Lee, Sandra A. O’Toole, Colin Clyne, Kylie L. Gorringe, Alexander Dobrovic,  and Stephen B. Fox
83626-83636
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Comparative efficacy and safety of immune checkpoint inhibitor-related therapies for advanced melanoma: a Bayesian network analysis

Comparative efficacy and safety of immune checkpoint inhibitor-related therapies for advanced melanoma: a Bayesian network analysis

https://doi.org/10.18632/oncotarget.18906

Xin Li, Junpeng Wang, Yun Yao, Lei Yang, Zhiqin Li, Cheng Yu, Peiyan Zhao, Yongli Yu,  and Liying Wang
83637-83649
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Peripheral CD4+ naïve/memory ratio is an independent predictor of survival in non-small cell lung cancer

Peripheral CD4+ naïve/memory ratio is an independent predictor of survival in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.19330

Peng Yang, Junhong Ma, Xin Yang,  and Wei Li
83650-83659
Abstract  |  PDF  |  HTML  |  How to cite

microRNA-33a-5p increases radiosensitivity by inhibiting glycolysis in melanoma

microRNA-33a-5p increases radiosensitivity by inhibiting glycolysis in melanoma

https://doi.org/10.18632/oncotarget.19014

Ke Cao, Jingjing Li, Jia Chen, Li Qian, Aijun Wang, Xiang Chen, Wei Xiong, Jintian Tang, Shijie Tang, Yong Chen, Yao Chen, Yan Cheng,  and Jianda Zhou
83660-83672
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

CEACAM6 is a prognostic biomarker and potential therapeutic target for gastric carcinoma

CEACAM6 is a prognostic biomarker and potential therapeutic target for gastric carcinoma

https://doi.org/10.18632/oncotarget.19415

Guo-Qing Ru, Yong Han, Wei Wang, Yuan Chen, Hui-Ju Wang, Wen-Juan Xu, Jie Ma, Meihua Ye, Xi Chen, Xiang-Lei He, Balázs Győrffy, Zhong-Sheng Zhao,  and Dongsheng Huang
83673-83683
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Hypoxia favors myosin heavy chain beta gene expression in an Hif-1alpha-dependent manner

Hypoxia favors myosin heavy chain beta gene expression in an Hif-1alpha-dependent manner

https://doi.org/10.18632/oncotarget.19016

Lucia Binó, Jiřina Procházková, Katarzyna Anna Radaszkiewicz, Jan Kučera, Jana Kudová, Jiří Pacherník,  and Lukáš Kubala
83684-83697
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Impact of tumor size and cirrhotic background for differentiating HCC and ICC with CEUS: does it matter for patients undergoing hepatectomy?

Impact of tumor size and cirrhotic background for differentiating HCC and ICC with CEUS: does it matter for patients undergoing hepatectomy?

https://doi.org/10.18632/oncotarget.19624

Chen Jin, Xiao-Yun Zhang, Jia-Wu Li, Chuan Li, Wei Peng, Tian-Fu Wen, Yan Luo, Qiang Lu, Xiao-Fei Zhong, Jing-Yi Zhang, Lv-Nan Yan,  and Jia-Yin Yang
83698-83711
Abstract  |  PDF  |  HTML  |  How to cite

Impact of VEGFA polymorphisms on glioma risk in Chinese

Impact of VEGFA polymorphisms on glioma risk in Chinese

https://doi.org/10.18632/oncotarget.19380

Peng Zhao, Anjing Chen, Qichao Qi, Wenjing Zhou, Zichao Feng, Jiwei Wang, Ning Yang, Xingang Li, Jian Wang, Qibing Huang,  and Bin Huang
83712-83722
Abstract  |  PDF  |  HTML  |  How to cite

An evaluation of nutrition intervention during radiation therapy in patients with locoregionally advanced nasopharyngeal carcinoma

An evaluation of nutrition intervention during radiation therapy in patients with locoregionally advanced nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.19381

Ting Jin, Kai-Xin Li, Pei-Jing Li, Shuang Huang, Xiao-Zhong Chen, Ming Chen, Qiao-Ying Hu, Lei Shi,  and Yuan-Yuan Chen
83723-83733
Abstract  |  PDF  |  HTML  |  How to cite

Trastuzumab distribution in an in-vivo and in-vitro model of brain metastases of breast cancer

Trastuzumab distribution in an in-vivo and in-vitro model of brain metastases of breast cancer

https://doi.org/10.18632/oncotarget.19634

Tori B. Terrell-Hall, Mohamed Ismail Nounou, Fatema El-Amrawy, Jessica I.G. Griffith,  and Paul R. Lockman
83734-83744
Abstract  |  PDF  |  HTML  |  How to cite

Diagnostic potential of serum exosomal colorectal neoplasia differentially expressed long non-coding RNA (CRNDE-p) and microRNA-217 expression in colorectal carcinoma

Diagnostic potential of serum exosomal colorectal neoplasia differentially expressed long non-coding RNA (CRNDE-p) and microRNA-217 expression in colorectal carcinoma

https://doi.org/10.18632/oncotarget.19407

Bo Yu, Qiong Du, Huan Li, Hong-Yue Liu, Xuan Ye, Bin Zhu, Qing Zhai,  and Xin-Xiang Li
83745-83753
Abstract  |  PDF  |  HTML  |  How to cite

Inhibitors of telomerase and poly(ADP-ribose) polymerases synergize to limit the lifespan of pancreatic cancer cells

Inhibitors of telomerase and poly(ADP-ribose) polymerases synergize to limit the lifespan of pancreatic cancer cells

https://doi.org/10.18632/oncotarget.19410

Katrina M. Burchett, Asserewou Etekpo, Surinder K. Batra, Ying Yan,  and Michel M. Ouellette
83754-83767
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Gene expression and molecular pathway activation signatures of MYCN-amplified neuroblastomas

Gene expression and molecular pathway activation signatures of MYCN-amplified neuroblastomas

https://doi.org/10.18632/oncotarget.19662

Ivan Petrov, Maria Suntsova, Elena Ilnitskaya, Sergey Roumiantsev, Maxim Sorokin, Andrew Garazha, Pavel Spirin, Timofey Lebedev, Nurshat Gaifullin, Sergey Larin, Olga Kovalchuk, Dmitry Konovalov, Vladimir Prassolov, Alexander Roumiantsev,  and Anton Buzdin
83768-83780
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Circulating long-chain n-3 polyunsaturated fatty acid and incidence of stroke: a meta-analysis of prospective cohort studies

Circulating long-chain n-3 polyunsaturated fatty acid and incidence of stroke: a meta-analysis of prospective cohort studies

https://doi.org/10.18632/oncotarget.19530

Bo Yang, Xiao-Li Ren, Hong Huang, Xiao-Juan Guo, Ai-Guo Ma,  and Duo Li
83781-83791
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Oral administration of Ginsenoside Rg1 prevents cardiac toxicity induced by doxorubicin in mice through anti-apoptosis

Oral administration of Ginsenoside Rg1 prevents cardiac toxicity induced by doxorubicin in mice through anti-apoptosis

https://doi.org/10.18632/oncotarget.19698

Chen Zhu, Yi Wang, Hua Liu, Haiman Mu, Yue Lu, Jiayi Zhang,  and Jianhua Huang
83792-83801
Abstract  |  PDF  |  HTML  |  How to cite

MiR-324-5p assists ultrasonography in predicting lymph node metastasis of unifocal papillary thyroid microcarcinoma without extracapsular spread

MiR-324-5p assists ultrasonography in predicting lymph node metastasis of unifocal papillary thyroid microcarcinoma without extracapsular spread

https://doi.org/10.18632/oncotarget.19717

Yanhua Yang, Shujun Xia, Xiaofeng Ni, Zhongxin Ni, Lu Zhang, Wenhan Wang, Yanjun Kong, Yan Wang, Lei Ye,  and Weiwei Zhan
83802-83816
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Improved outcome of haploidentical transplantation in severe aplastic anemia using reduced-intensity fludarabine-based conditioning

Improved outcome of haploidentical transplantation in severe aplastic anemia using reduced-intensity fludarabine-based conditioning

https://doi.org/10.18632/oncotarget.19745

Wu Yamei, Luo Rongmu, Cao Yongbin, Si Yingjian, Li Xiaohong, Zhang Xiaomei, Yan Pei, Du Zhenlan, Wang Haitao, Wang Jing, Wang Bojing, Wu Xiaoxiong,  and Da Wanming
83817-83830
Abstract  |  PDF  |  HTML  |  How to cite

Mitochondrial calcium uniporter as a target of microRNA-340 and promoter of metastasis via enhancing the Warburg effect

Mitochondrial calcium uniporter as a target of microRNA-340 and promoter of metastasis via enhancing the Warburg effect

https://doi.org/10.18632/oncotarget.19747

Changhui Yu, Yuhao Wang, Jiawen Peng, Qiang Shen, Mimi Chen, Wei Tang, Xiumei Li, Chunqing Cai, Bin Wang, Shaoxi Cai, Xiaojing Meng,  and Fei Zou
83831-83844
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Infrequently expressed miRNAs influence survival after diagnosis with colorectal cancer

Infrequently expressed miRNAs influence survival after diagnosis with colorectal cancer

https://doi.org/10.18632/oncotarget.19863

Martha L. Slattery, Andrew J. Pellatt, Frances Y. Lee, Jennifer S. Herrick, Wade S. Samowitz, John R. Stevens, Roger K. Wolff,  and Lila E. Mullany
83845-83859
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Rapid and accurate detection of KRAS mutations in colorectal cancers using the isothermal-based optical sensor for companion diagnostics

Rapid and accurate detection of KRAS mutations in colorectal cancers using the isothermal-based optical sensor for companion diagnostics

https://doi.org/10.18632/oncotarget.20038

Choong Eun Jin, Seung-Seop Yeom, Bonhan Koo, Tae Yoon Lee, Jeong Hoon Lee, Yong Shin,  and Seok-Byung Lim
83860-83871
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Targeting Src attenuates peritoneal fibrosis and inhibits the epithelial to mesenchymal transition

Targeting Src attenuates peritoneal fibrosis and inhibits the epithelial to mesenchymal transition

https://doi.org/10.18632/oncotarget.20040

Jun Wang, Li Wang, Liuqing Xu, Yingfeng Shi, Feng Liu, Hualin Qi, Na Liu,  and Shougang Zhuang
83872-83889
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

A cocktail of p16INK4a and Ki-67, p16INK4a and minichromosome maintenance protein 2 as triage tests for human papillomavirus primary cervical cancer screening

A cocktail of p16INK4a and Ki-67, p16INK4a and minichromosome maintenance protein 2 as triage tests for human papillomavirus primary cervical cancer screening

https://doi.org/10.18632/oncotarget.19870

Hai-Rui Wang, Yu-Cong Li, Hui-Qin Guo, Lu-Lu Yu, Zeni Wu, Jian Yin, Guang-Dong Liao, Yi-Min Qu, Yu Jiang, Dong Wang,  and Wen Chen
83890-83899
Abstract  |  PDF  |  HTML  |  How to cite

Activated spleen tyrosine kinase promotes malignant progression of oral squamous cell carcinoma via mTOR/S6 signaling pathway in an ERK1/2-independent manner

Activated spleen tyrosine kinase promotes malignant progression of oral squamous cell carcinoma via mTOR/S6 signaling pathway in an ERK1/2-independent manner

https://doi.org/10.18632/oncotarget.19911

Pan Gao, Xianghe Qiao, Haibin Sun, Yi Huang, Jie Lin, Longjiang Li, Xiaoyi Wang,  and Chunjie Li
83900-83912
Abstract  |  PDF  |  HTML  |  How to cite

Selective secretion of microRNAs from lung cancer cells via extracellular vesicles promotes CAMK1D-mediated tube formation in endothelial cells

Selective secretion of microRNAs from lung cancer cells via extracellular vesicles promotes CAMK1D-mediated tube formation in endothelial cells

https://doi.org/10.18632/oncotarget.19996

James Lawson, Christopher Dickman, Sara MacLellan, Rebecca Towle, James Jabalee, Stephen Lam,  and Cathie Garnis
83913-83924
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Synergistic effect of eribulin and CDK inhibition for the treatment of triple negative breast cancer

Synergistic effect of eribulin and CDK inhibition for the treatment of triple negative breast cancer

https://doi.org/10.18632/oncotarget.20202

Shreyas S. Rao, Jenna Stoehr, Danijela Dokic, Lei Wan, Joseph T. Decker, Kristine Konopka, Alexandra L. Thomas, Jia Wu, Virginia G. Kaklamani, Lonnie D. Shea,  and Jacqueline S. Jeruss
83925-83939
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Measuring plasma levels of three microRNAs can improve the accuracy for identification of malignant breast lesions in women with BI-RADS 4 mammography

Measuring plasma levels of three microRNAs can improve the accuracy for identification of malignant breast lesions in women with BI-RADS 4 mammography

https://doi.org/10.18632/oncotarget.20806

Julia Alejandra Pezuk, Thiago Luiz Araujo Miller, José Luiz Barbosa Bevilacqua, Alfredo Carlos Simões Dornellas de Barro, Felipe Eduardo Martins de Andrade, Luiza Freire de Andrade e Macedo, Vera Aguilar, Amanda Natasha Menardo Claro, Anamaria Aranha Camargo, Pedro Alexandre Favoretto Galante,  and Luiz F. L. Reis
83940-83948
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Lithium chloride inhibits titanium particle-induced osteoclastogenesis by inhibiting the NF-κB pathway

Lithium chloride inhibits titanium particle-induced osteoclastogenesis by inhibiting the NF-κB pathway

https://doi.org/10.18632/oncotarget.20000

Xuanyang Hu, Zhirong Wang, Jiawei Shi, Xiaobin Guo, Liangliang Wang, Zichuan Ping, Yunxia Tao, Huilin Yang, Jun Zhou, Yaozeng Xu,  and Dechun Geng
83949-83961
Abstract  |  PDF  |  HTML  |  How to cite

TGFBR-IDH1-Cav1 axis promotes TGF-β signalling in cancer-associated fibroblast

TGFBR-IDH1-Cav1 axis promotes TGF-β signalling in cancer-associated fibroblast

https://doi.org/10.18632/oncotarget.20861

Xiaodan Hou, Jieying Zhang, Yongbin Wang, Wujun Xiong,  and Jun Mi
83962-83974
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

DNA mismatch repair protein Mlh1 is required for tetravalent chromium intermediate-induced DNA damage

DNA mismatch repair protein Mlh1 is required for tetravalent chromium intermediate-induced DNA damage

https://doi.org/10.18632/oncotarget.20150

Timothy P. Wakeman, Aimin Yang, Naresh S. Dalal, Rebecca J Boohaker, Qinghua Zeng, Qiang Ding,  and Bo Xu
83975-83985
Abstract  |  PDF  |  HTML  |  How to cite

Prognostic significance of PD-L1 expression and tumor infiltrating lymphocyte in surgically resectable non-small cell lung cancer

Prognostic significance of PD-L1 expression and tumor infiltrating lymphocyte in surgically resectable non-small cell lung cancer

https://doi.org/10.18632/oncotarget.20233

Gen Lin, Xirong Fan, Weifeng Zhu, Cheng Huang, Wu Zhuang, Haipeng Xu, Xiandong Lin, Dan Hu, Yunjian Huang, Kan Jiang, Qian Miao,  and Chao Li
83986-83994
Abstract  |  PDF  |  HTML  |  How to cite

Molecular characteristics and serodiagnostic potential of chitinase-like protein from Sarcoptes scabiei

Molecular characteristics and serodiagnostic potential of chitinase-like protein from Sarcoptes scabiei

https://doi.org/10.18632/oncotarget.21056

Ran He, Nengxing Shen, Haojie Zhang, Yongjun Ren, Manli He, Jing Xu, Cheng Guo, Yue Xie, Xiaobin Gu, Weimin Lai, Xuerong Peng,  and Guangyou Yang
83995-84005
Abstract  |  PDF  |  HTML  |  How to cite

Downregulation of the Sonic Hedgehog/Gli pathway transcriptional target Neogenin-1 is associated with basal cell carcinoma aggressiveness

Downregulation of the Sonic Hedgehog/Gli pathway transcriptional target Neogenin-1 is associated with basal cell carcinoma aggressiveness

https://doi.org/10.18632/oncotarget.21061

Bárbara S. Casas, Christelle Adolphe, Pablo Lois, Nelson Navarrete, Natalia Solís, Eva Bustamante, Patricio Gac, Patricio Cabané, Ivan Gallegos, Brandon J. Wainwright,  and Verónica Palma
84006-84018
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Hormone receptors expression in ovarian cancer taking into account menopausal status: a retrospective study in Chinese population

Hormone receptors expression in ovarian cancer taking into account menopausal status: a retrospective study in Chinese population

https://doi.org/10.18632/oncotarget.20251

Fang Shen, Xuyin Zhang, Yiqun Zhang, Jingxin Ding,  and Qi Chen
84019-84027
Abstract  |  PDF  |  HTML  |  How to cite

BDNF/TrkB signaling mediates the anorectic action of estradiol in the nucleus tractus solitarius

BDNF/TrkB signaling mediates the anorectic action of estradiol in the nucleus tractus solitarius

https://doi.org/10.18632/oncotarget.21062

Ling Shen, David Q.H. Wang, Meifeng Xu, Stephen C. Woods,  and Min Liu
84028-84038
Abstract  |  PDF  |  HTML  |  How to cite

Chicken CCDC152 shares an NFYB-regulated bidirectional promoter with a growth hormone receptor antisense transcript and inhibits cells proliferation and migration

Chicken CCDC152 shares an NFYB-regulated bidirectional promoter with a growth hormone receptor antisense transcript and inhibits cells proliferation and migration

https://doi.org/10.18632/oncotarget.21091

Shudai Lin, Wei Luo, Mingya Jiang, Wen Luo, Bahareldin Ali Abdalla, Qinghua Nie, Li Zhang,  and Xiquan Zhang
84039-84053
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

The role of TFPI2 hypermethylation in the detection of gastric and colorectal cancer

The role of TFPI2 hypermethylation in the detection of gastric and colorectal cancer

https://doi.org/10.18632/oncotarget.21097

Haochang Hu, Xiaoying Chen, Cheng Wang, Yuting Jiang, Jingjing Li, Xiuru Ying, Yong Yang, Bin Li, Cong Zhou, Jie Zhong, Dongping Wu, Jieer Ying,  and Shiwei Duan
84054-84065
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Necroptosis regulated proteins expression is an early prognostic biomarker in patient with sepsis: a prospective observational study

Necroptosis regulated proteins expression is an early prognostic biomarker in patient with sepsis: a prospective observational study

https://doi.org/10.18632/oncotarget.21099

Bing Wang, Jian Li, Hong-Mei Gao, Ying-Hong Xing, Zhu Lin, Hong-Jie Li,  and Yong-Qiang Wang
84066-84073
Abstract  |  PDF  |  HTML  |  How to cite

The forkhead box C1 (FOXC1) transcription factor is downregulated in acute promyelocytic leukemia

The forkhead box C1 (FOXC1) transcription factor is downregulated in acute promyelocytic leukemia

https://doi.org/10.18632/oncotarget.21101

Emiliano Fabiani, Giulia Falconi, Nélida Inés Noguera, Ernestina Saulle, Laura Cicconi, Mariadomenica Divona, Cristina Banella, Alessandra Picardi, Anna Maria Cerio, Letizia Boe, Massimo Sanchez, Elvira Pelosi, Ugo Testa, Francesco Lo-Coco,  and Maria Teresa Voso
84074-84085
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

LncRNA SNHG12 contributes to multidrug resistance through activating the MAPK/Slug pathway by sponging miR-181a in non-small cell lung cancer

LncRNA SNHG12 contributes to multidrug resistance through activating the MAPK/Slug pathway by sponging miR-181a in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.20475

Pei Wang, Dong Chen, Hongbing Ma,  and Yong Li
84086-84101
Abstract  |  PDF  |  HTML  |  How to cite

Incidence and risk of regorafenib-induced hepatotoxicity

Incidence and risk of regorafenib-induced hepatotoxicity

https://doi.org/10.18632/oncotarget.21106

Bin Zhao,  and Hong Zhao
84102-84111
Abstract  |  PDF  |  HTML  |  How to cite

Overexpression of CTEN relates to tumor malignant potential and poor outcomes of adenocarcinoma of the esophagogastric junction

Overexpression of CTEN relates to tumor malignant potential and poor outcomes of adenocarcinoma of the esophagogastric junction

https://doi.org/10.18632/oncotarget.21109

Kenichi Aratani, Shuhei Komatsu, Daisuke Ichikawa, Takuma Ohashi, Mahito Miyamae, Wataru Okajima, Taisuke Imamura, Jun Kiuchi, Keiji Nishibeppu, Toshiyuki Kosuga, Hirotaka Konishi, Atsushi Shiozaki, Hitoshi Fujiwara, Kazuma Okamoto, Hitoshi Tsuda,  and Eigo Otsuji
84112-84122
Abstract  |  PDF  |  HTML  |  How to cite

LINC00461, a long non-coding RNA, is important for the proliferation and migration of glioma cells

LINC00461, a long non-coding RNA, is important for the proliferation and migration of glioma cells

https://doi.org/10.18632/oncotarget.20340

Yali Yang, Mingxin Ren, Chao Song, Dan Li, Shahid Hussain Soomro, Yajie Xiong, Hongfeng Zhang,  and Hui Fu
84123-84139
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

A novel polyamine blockade therapy activates an anti-tumor immune response

A novel polyamine blockade therapy activates an anti-tumor immune response

https://doi.org/10.18632/oncotarget.20493

Eric T. Alexander, Allyson Minton, Molly C. Peters, Otto Phanstiel IV,  and Susan K. Gilmour
84140-84152
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Long non-coding RNA SNHG15 inhibits P15 and KLF2 expression to promote pancreatic cancer proliferation through EZH2-mediated H3K27me3

Long non-coding RNA SNHG15 inhibits P15 and KLF2 expression to promote pancreatic cancer proliferation through EZH2-mediated H3K27me3

https://doi.org/10.18632/oncotarget.20359

Zhonghua Ma, Hesuyuan Huang, Jirong Wang, Yan Zhou, Fuxing Pu, Qinghong Zhao, Peng Peng, Bingqing Hui, Hao Ji,  and Keming Wang
84153-84167
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Abnormal neural activities of directional brain networks in patients with long-term bilateral hearing loss

Abnormal neural activities of directional brain networks in patients with long-term bilateral hearing loss

https://doi.org/10.18632/oncotarget.20361

Long-Chun Xu, Gang Zhang, Yue Zou, Min-Feng Zhang, Dong-Sheng Zhang, Hua Ma, Wen-Bo Zhao,  and Guang-Yu Zhang
84168-84179
Abstract  |  PDF  |  HTML  |  How to cite

Salvage lymph node dissection after 68Ga-PSMA or 18F-FEC PET/CT for nodal recurrence in prostate cancer patients

Salvage lymph node dissection after 68Ga-PSMA or 18F-FEC PET/CT for nodal recurrence in prostate cancer patients

https://doi.org/10.18632/oncotarget.21118

Annika Herlemann, Alexander Kretschmer, Alexander Buchner, Alexander Karl, Stefan Tritschler, Lina El-Malazi, Wolfgang P. Fendler, Vera Wenter, Harun Ilhan, Peter Bartenstein, Christian G. Stief,  and Christian Gratzke
84180-84192
Abstract  |  PDF  |  HTML  |  How to cite

Ubiquitin conjugating enzyme E2 L3 promoted tumor growth of NSCLC through accelerating p27kip1 ubiquitination and degradation

Ubiquitin conjugating enzyme E2 L3 promoted tumor growth of NSCLC through accelerating p27kip1 ubiquitination and degradation

https://doi.org/10.18632/oncotarget.20449

Xingjie Ma, Junjie Zhao, Fan Yang, Haitao Liu,  and Weibo Qi
84193-84203
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Analysis of clinical and neurological outcomes in patients with cauda equina syndrome caused by acute lumbar disc herniation: a retrospective-prospective study

Analysis of clinical and neurological outcomes in patients with cauda equina syndrome caused by acute lumbar disc herniation: a retrospective-prospective study

https://doi.org/10.18632/oncotarget.20453

Si-Dong Yang, Feng Zhang,  and Wen-Yuan Ding
84204-84209
Abstract  |  PDF  |  HTML  |  How to cite

Inhibition of retinoic acid receptor β signaling confers glycolytic dependence and sensitization to dichloroacetate in melanoma cells

Inhibition of retinoic acid receptor β signaling confers glycolytic dependence and sensitization to dichloroacetate in melanoma cells

https://doi.org/10.18632/oncotarget.20476

Cecilie Abildgaard, Christina Dahl, Ahmad Abdul-Al, Annette Christensen,  and Per Guldberg
84210-84223
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

A randomized phase II study of aromatase inhibitors plus metformin in pre-treated postmenopausal patients with hormone receptor positive metastatic breast cancer

A randomized phase II study of aromatase inhibitors plus metformin in pre-treated postmenopausal patients with hormone receptor positive metastatic breast cancer

https://doi.org/10.18632/oncotarget.20478

Yannan Zhao, Chengcheng Gong, Zhonghua Wang, Jian Zhang, Leiping Wang, Sheng Zhang, Jun Cao, Zhonghua Tao, Ting Li, Biyun Wang,  and Xichun Hu
84224-84236
Abstract  |  PDF  |  HTML  |  How to cite

Caspase-3 expression in tumorigenesis and prognosis of buccal mucosa squamous cell carcinoma

Caspase-3 expression in tumorigenesis and prognosis of buccal mucosa squamous cell carcinoma

https://doi.org/10.18632/oncotarget.20494

Jer-Shyung Huang, Cheng-Mei Yang, Jyh-Seng Wang, Huei-Han Liou, I-Chien Hsieh, Guan-Cheng Li, Sin-Jhih Huang, Chih-Wen Shu, Ting-Ying Fu, Yun-Chung Lin, Luo-Ping Ger,  and Pei-Feng Liu
84237-84247
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Anti-angiogenic and anti-tumor effects of metronomic use of novel liposomal zoledronic acid depletes tumor-associated macrophages in triple negative breast cancer

Anti-angiogenic and anti-tumor effects of metronomic use of novel liposomal zoledronic acid depletes tumor-associated macrophages in triple negative breast cancer

https://doi.org/10.18632/oncotarget.20539

Xin-Jun Cai, Zeng Wang, Jia-Wei Cao, Jian-Jun Ni, Ying-Ying Xu, Jun Yao, Hong Xu, Fang Liu,  and Gao-Yi Yang
84248-84257
Abstract  |  PDF  |  HTML  |  How to cite

GPER mediates differential effects of estrogen on colon cancer cell proliferation and migration under normoxic and hypoxic conditions

GPER mediates differential effects of estrogen on colon cancer cell proliferation and migration under normoxic and hypoxic conditions

https://doi.org/10.18632/oncotarget.20653

Viviana Bustos, Áine M. Nolan, Anke Nijhuis, Harry Harvey, Alexandra Parker, Richard Poulsom, Jean McBryan, Warren Thomas, Andrew Silver,  and Brian J. Harvey
84258-84275
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Pkm2 can enhance pluripotency in ESCs and promote somatic cell reprogramming to iPSCs

Pkm2 can enhance pluripotency in ESCs and promote somatic cell reprogramming to iPSCs

https://doi.org/10.18632/oncotarget.20685

Shengtang Qin, Danli Yang, Kang Chen, Haolan Li, Liqiang Zhang, Yuan Li, Rongrong Le, Xiaojie Li, Shaorong Gao,  and Lan Kang
84276-84284
Abstract  |  PDF  |  HTML  |  How to cite

Expression of the β3 subunit of Na+/K+-ATPase is increased in gastric cancer and regulates gastric cancer cell progression and prognosis via the PI3/AKT pathway

Expression of the β3 subunit of Na+/K+-ATPase is increased in gastric cancer and regulates gastric cancer cell progression and prognosis via the PI3/AKT pathway

https://doi.org/10.18632/oncotarget.20894

Li Li, Ru Feng, Qian Xu, Feiyue Zhang, Tong Liu, Jiang Cao,  and Sujuan Fei
84285-84299
Abstract  |  PDF  |  HTML  |  How to cite

Septicemia is associated with increased risk for dementia: a population-based longitudinal study

Septicemia is associated with increased risk for dementia: a population-based longitudinal study

https://doi.org/10.18632/oncotarget.20899

Chung-Hsing Chou, Jiunn-Tay Lee, Chun-Chieh Lin, Yueh-Feng Sung, Che-Chen Lin, Chih-Hsin Muo, Fu-Chi Yang, Chi-Pang Wen, I-Kuan Wang, Chia-Hung Kao, Chung Y. Hsu,  and Chun-Hung Tseng
84300-84308
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

A fatal case of mitochondrial DNA depletion syndrome with novel compound heterozygous variants in the deoxyguanosine kinase gene

A fatal case of mitochondrial DNA depletion syndrome with novel compound heterozygous variants in the deoxyguanosine kinase gene

https://doi.org/10.18632/oncotarget.20905

Weiyuan Fang, Peng Song, Xinbao Xie, Jianshe Wang, Yi Lu, Gang Li,  and Kuerbanjiang Abuduxikuer
84309-84319
Abstract  |  PDF  |  HTML  |  How to cite

Therapeutic implications of tumor free margins in head and neck squamous cell carcinoma

Therapeutic implications of tumor free margins in head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.21035

Clara Backes, Henning Bier,  and Andreas Knopf
84320-84328
Abstract  |  PDF  |  HTML  |  How to cite

Association of opioid receptor mu 1 (OPRM1) A118G polymorphism (rs1799971) with nicotine dependence

Association of opioid receptor mu 1 (OPRM1) A118G polymorphism (rs1799971) with nicotine dependence

https://doi.org/10.18632/oncotarget.20939

Xiangyi Kong, Hao Deng, Theodore Alston, Yanguo Kong,  and Jingping Wang
84329-84337
Abstract  |  PDF  |  HTML  |  How to cite

PTEN loss is associated with prostate cancer recurrence and alterations in tumor DNA methylation profiles

PTEN loss is associated with prostate cancer recurrence and alterations in tumor DNA methylation profiles

https://doi.org/10.18632/oncotarget.20940

Milan S. Geybels, Min Fang, Jonathan L. Wright, Xiaoyu Qu, Marina Bibikova, Brandy Klotzle, Jian-Bing Fan, Ziding Feng, Elaine A. Ostrander, Peter S. Nelson,  and Janet L. Stanford
84338-84348
Abstract  |  PDF  |  HTML  |  How to cite

Survival rate variation with different histological subtypes of poor prognostic male anal squamous cell carcinoma: a population-based study

Survival rate variation with different histological subtypes of poor prognostic male anal squamous cell carcinoma: a population-based study

https://doi.org/10.18632/oncotarget.20969

Zihao Wan, Zhihao Huang, Vikash Vikash, Kelash Rai, Sindhu Vikash, Liaobin Chen,  and Jingfeng Li
84349-84359
Abstract  |  PDF  |  HTML  |  How to cite

Genome-wide analysis and functional prediction of long non-coding RNAs in mouse uterus during the implantation window

Genome-wide analysis and functional prediction of long non-coding RNAs in mouse uterus during the implantation window

https://doi.org/10.18632/oncotarget.21031

Qi Wang, Nan Wang, Rui Cai, Fan Zhao, Yongjie Xiong, Xiao Li, Aihua Wang, Pengfei Lin,  and Yaping Jin
84360-84372
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Mitochondrial DNA depletion, mitochondrial mutations and high TFAM expression in hepatocellular carcinoma

Mitochondrial DNA depletion, mitochondrial mutations and high TFAM expression in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.21033

Lihua Qiao, Guoqing Ru, Zhuochao Mao, Chenghui Wang, Zhipeng Nie, Qiang Li, Yiyi Huang-yang, Ling Zhu, Xiaoyang Liang, Jialing Yu,  and Pingping Jiang
84373-84383
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

MiR-143 inhibits endometrial cancer cell proliferation and metastasis by targeting MAPK1

MiR-143 inhibits endometrial cancer cell proliferation and metastasis by targeting MAPK1

https://doi.org/10.18632/oncotarget.21037

Lei Chang, Dongya Zhang, Huirong Shi, Yangyang Bian,  and Ruixia Guo
84384-84395
Abstract  |  PDF  |  HTML  |  How to cite

Upregulation of homeobox gene is correlated with poor survival outcomes in cervical cancer

Upregulation of homeobox gene is correlated with poor survival outcomes in cervical cancer

https://doi.org/10.18632/oncotarget.21041

Kyung Jin Eoh, Hee Jung Kim, Jung-Yun Lee, Eun Ji Nam, Sunghoon Kim, Sang Wun Kim,  and Young Tae Kim
84396-84402
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Involment of RAS/ERK1/2 signaling and MEF2C in miR-155-3p inhibition-triggered cardiomyocyte differentiation of embryonic stem cell

Involment of RAS/ERK1/2 signaling and MEF2C in miR-155-3p inhibition-triggered cardiomyocyte differentiation of embryonic stem cell

https://doi.org/10.18632/oncotarget.21218

Xiang Ling, Dongbo Yao, Lumei Kang, Jing Zhou, Ying Zhou, Hui Dong, Keping Zhang, Lei Zhang,  and Hongping Chen
84403-84416
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Recurrent mutations in a SERPINC1 hotspot associate with venous thrombosis without apparent antithrombin deficiency

Recurrent mutations in a SERPINC1 hotspot associate with venous thrombosis without apparent antithrombin deficiency

https://doi.org/10.18632/oncotarget.21365

Wei Zeng, Bei Hu, Liang Tang, Yan-Yan You, Mara Toderici, Maria Eugenia de la Morena-Barrio, Javier Corral,  and Yu Hu
84417-84425
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Tumor-biopsy stratification based on mTOR-pathway activity and functional mutations in the upstream genes PIK3CA and PTEN

Tumor-biopsy stratification based on mTOR-pathway activity and functional mutations in the upstream genes PIK3CA and PTEN

https://doi.org/10.18632/oncotarget.21348

Jean-François Laes, Sebastien Sauvage,  and Gregori Ghitti
84426-84433
Abstract  |  PDF  |  HTML  |  How to cite

DNA hypermethyation and silencing of PITX1 correlated with advanced stage and poor postoperative prognosis of esophageal squamous cell carcinoma

DNA hypermethyation and silencing of PITX1 correlated with advanced stage and poor postoperative prognosis of esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.21375

Takeshi Otsubo, Kazuhiko Yamada, Teruki Hagiwara, Kenshiro Oshima, Kei Iida, Koro Nishikata, Tetsuro Toyoda, Toru Igari, Kyoko Nohara, Satoshi Yamashita, Masahira Hattori, Taeko Dohi,  and Yuki I. Kawamura
84434-84448
Abstract  |  PDF  |  HTML  |  How to cite

Meta-Analysis

Prognostic value of bone scan index as an imaging biomarker in metastatic prostate cancer: a meta-analysis

Prognostic value of bone scan index as an imaging biomarker in metastatic prostate cancer: a meta-analysis

https://doi.org/10.18632/oncotarget.19680

Dongyang Li, Hang Lv, Xuanyu Hao, Yudi Dong, Huixu Dai,  and Yongsheng Song
84449-84458
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Association between alcohol consumption and the risk of gastric cancer: a meta-analysis of prospective cohort studies

Association between alcohol consumption and the risk of gastric cancer: a meta-analysis of prospective cohort studies

https://doi.org/10.18632/oncotarget.20880

Zheng He, Ting-Ting Zhao, Hui-Mian Xu, Zhen-Ning Wang, Ying-Ying Xu, Yong-Xi Song, Zhong-Ran Ni, Hao Xu, Song-Cheng Yin, Xing-Yu Liu,  and Zhi-Feng Miao
84459-84472
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Comparison of DWI and 18F-FDG PET/CT for assessing preoperative N-staging in gastric cancer: evidence from a meta-analysis

Comparison of DWI and 18F-FDG PET/CT for assessing preoperative N-staging in gastric cancer: evidence from a meta-analysis

https://doi.org/10.18632/oncotarget.21055

Mingxu Luo, Hongmei Song, Gang Liu, Yikai Lin, Lintao Luo, Xin Zhou,  and Bo Chen
84473-84488
Abstract  |  PDF  |  HTML  |  How to cite

Aberrations in circulating inflammatory cytokine levels in patients with Down syndrome: a meta-analysis

Aberrations in circulating inflammatory cytokine levels in patients with Down syndrome: a meta-analysis

https://doi.org/10.18632/oncotarget.21060

Yan Zhang, Meng Che, Jing Yuan, Yun Yu, Chang Cao, Xiao-Yan Qin,  and Yong Cheng
84489-84496
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Prognostic value of long noncoding RNA ZFAS1 in various carcinomas: a meta-analysis

Prognostic value of long noncoding RNA ZFAS1 in various carcinomas: a meta-analysis

https://doi.org/10.18632/oncotarget.21100

Dan Dong, Zhongyi Mu, Wei Wang, Na Xin, Xiaowen Song, Yue Shao,  and Chenghai Zhao
84497-84505
Abstract  |  PDF  |  HTML  |  How to cite

The clinical use of the platelet to lymphocyte ratio and lymphocyte to monocyte ratio as prognostic factors in renal cell carcinoma: a systematic review and meta-analysis

The clinical use of the platelet to lymphocyte ratio and lymphocyte to monocyte ratio as prognostic factors in renal cell carcinoma: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.21108

Xuemin Wang, Shiqiang Su,  and Yuanshan Guo
84506-84514
Abstract  |  PDF  |  HTML  |  How to cite

Clinical Research Papers

Impact of splenic hilar lymph node metastasis on prognosis in patients with advanced gastric cancer

Impact of splenic hilar lymph node metastasis on prognosis in patients with advanced gastric cancer

https://doi.org/10.18632/oncotarget.18762

Taeil Son, In Gyu Kwon, Joong Ho Lee, Youn Young Choi, Hyoung-Il Kim, Jae-Ho Cheong, Sung Hoon Noh,  and Woo Jin Hyung
84515-84528
Abstract  |  PDF  |  HTML  |  How to cite

Altered resting-state functional activity in isolated pontine infarction patients with pathological laughing and crying

Altered resting-state functional activity in isolated pontine infarction patients with pathological laughing and crying

https://doi.org/10.18632/oncotarget.19307

Tao Liu, Jianjun Li, Shixiong Huang, Changqinq Li, Zhongyan Zhao, Guoqiang Wen,  and Feng Chen
84529-84539
Abstract  |  PDF  |  HTML  |  How to cite

Suspected cancer diagnoses made by general practitioners in a population with subsequently confirmed cancer diagnoses in Germany: a retrospective study of 31,628 patients

Suspected cancer diagnoses made by general practitioners in a population with subsequently confirmed cancer diagnoses in Germany: a retrospective study of 31,628 patients

https://doi.org/10.18632/oncotarget.20886

Karel Kostev, Uwe Meister, Matthias Kalder,  and Louis Jacob
84540-84545
Abstract  |  PDF  |  HTML  |  How to cite

Reviews

Thrombospondin-1 is a multifaceted player in tumor progression

Thrombospondin-1 is a multifaceted player in tumor progression

https://doi.org/10.18632/oncotarget.19165

Tingting Huang, Li Sun, Xianglin Yuan,  and Hong Qiu
84546-84558
Abstract  |  PDF  |  HTML  |  How to cite

Novel strategies to prevent the development of multidrug resistance (MDR) in cancer

Novel strategies to prevent the development of multidrug resistance (MDR) in cancer

https://doi.org/10.18632/oncotarget.19187

Jinglu Wang, Nicole Seebacher, Huirong Shi, Quancheng Kan,  and Zhenfeng Duan
84559-84571
Abstract  |  PDF  |  HTML  |  How to cite

Differential side effects profile in patients with mCRPC treated with abiraterone or enzalutamide: a meta-analysis of randomized controlled trials

Differential side effects profile in patients with mCRPC treated with abiraterone or enzalutamide: a meta-analysis of randomized controlled trials

https://doi.org/10.18632/oncotarget.20028

Raphael B. Moreira, Marcio Debiasi, Edoardo Francini, Pier V. Nuzzo, Guillermo De Velasco, Fernando C. Maluf, Andre P. Fay, Joaquim Bellmunt, Toni K. Choueiri,  and Fabio A. Schutz
84572-84578
Abstract  |  PDF  |  HTML  |  How to cite

Moving forward with actionable therapeutic targets and opportunities in endometrial cancer: NCI clinical trials planning meeting report on identifying key genes and molecular pathways for targeted endometrial cancer trials

Moving forward with actionable therapeutic targets and opportunities in endometrial cancer: NCI clinical trials planning meeting report on identifying key genes and molecular pathways for targeted endometrial cancer trials

https://doi.org/10.18632/oncotarget.19961

Helen J. MacKay, Douglas A. Levine, Victoria L. Bae-Jump, Daphne W. Bell, Jessica N. McAlpine, Alessandro Santin, Gini F. Fleming, David G. Mutch, Kenneth P. Nephew, Nicolas Wentzensen, Paul J. Goodfellow, Oliver Dorigo, Hans W. Nijman, Russell Broaddus,  and Elise C. Kohn
84579-84594
Abstract  |  PDF  |  HTML  |  How to cite

The transcription factor ATF5: role in cellular differentiation, stress responses, and cancer

The transcription factor ATF5: role in cellular differentiation, stress responses, and cancer

https://doi.org/10.18632/oncotarget.21102

Thomas K. Sears,  and James M. Angelastro
84595-84609
Abstract  |  PDF  |  HTML  |  How to cite


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