Oncotarget

Volume 15 (2024)

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Table of Contents

Research Papers

ATR inhibition using gartisertib enhances cell death and synergises with temozolomide and radiation in patient-derived glioblastoma cell lines

ATR inhibition using gartisertib enhances cell death and synergises with temozolomide and radiation in patient-derived glioblastoma cell lines

https://doi.org/10.18632/oncotarget.28551

Mathew Lozinski, Nikola A. Bowden, Moira C. Graves, Michael Fay, Bryan W. Day, Brett W. Stringer,  and Paul A. Tooney
1-18
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Retraction

Retraction: Decreased long intergenic noncoding RNA P7 predicts unfavorable prognosis and promotes tumor proliferation via the modulation of the STAT1-MAPK pathway in hepatocellular carcinoma

Retraction: Decreased long intergenic noncoding RNA P7 predicts unfavorable prognosis and promotes tumor proliferation via the modulation of the STAT1-MAPK pathway in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.28366

Sijie Cheng, Tieling Li, Cheng Wang, Keyu Wang, Chengcai Lai, Jin Yan, Hongxia Fan, Fang Sun, Zhaohai Wang, Peirui Zhang, Linxiang Yu, Zhixian Hong, Guanglin Lei, Baijun Sun, Yuan Gao, Zhaohui Xiao, Xu Ji, Ruilan Wang, Jianzhong Wu, Xiliang Wang, Shaogeng Zhang,  and Penghui Yang
19-19
Retraction  |  PDF  |  How to cite

Research Perspectives

Bone marrow adipocytes provide early sign for progression from MGUS to multiple myeloma

Bone marrow adipocytes provide early sign for progression from MGUS to multiple myeloma

https://doi.org/10.18632/oncotarget.28548

Bilal M. El-Masri, Benedeta Leka, Fatima Mustapha, Michael Tveden Gundesen, Maja Hinge, Thomas Lund, Thomas L. Andersen, Marta Diaz-delCastillo,  and Abbas Jafari
20-26
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Case Reports

Lazarus effect in a patient initially empirically treated with osimertinib for EGFR L858R mutant non-small cell lung cancer with leptomeningeal disease: a case report

Lazarus effect in a patient initially empirically treated with osimertinib for EGFR L858R mutant non-small cell lung cancer with leptomeningeal disease: a case report

https://doi.org/10.18632/oncotarget.28550

Shreya Bhatia, Manuel G. Cortez, Spencer Lessans,  and Wade T. Iams
27-30
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

The fate of drug discovery in academia; dumping in the publication landfill?

The fate of drug discovery in academia; dumping in the publication landfill?

https://doi.org/10.18632/oncotarget.28552

Uzma Saqib, Isaac S. Demaree, Alexander G. Obukhov, Mirza S. Baig, Amiram Ariel,  and Krishnan Hajela
31-34
PDF  |  How to cite  |  Press Release

Retraction

Retraction: Interferon gamma peptidomimetic targeted to interstitial myofibroblasts attenuates renal fibrosis after unilateral ureteral obstruction in mice

Retraction: Interferon gamma peptidomimetic targeted to interstitial myofibroblasts attenuates renal fibrosis after unilateral ureteral obstruction in mice

https://doi.org/10.18632/oncotarget.28532

Fariba Poosti, Ruchi Bansal, Saleh Yazdani, Jai Prakash, Leonie Beljaars, Jacob van den Born, Martin H. de Borst, Harry van Goor, Jan-Luuk Hillebrands,  and Klaas Poelstra
35-35
Retraction  |  PDF  |  How to cite

Research Perspectives

Genetic alterations in thyroid cancer mediating both resistance to BRAF inhibition and anaplastic transformation

Genetic alterations in thyroid cancer mediating both resistance to BRAF inhibition and anaplastic transformation

https://doi.org/10.18632/oncotarget.28544

Mark Lee,  and Luc GT Morris
36-48
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Papers

BCAS1 defines a heterogeneous cell population in diffuse gliomas

BCAS1 defines a heterogeneous cell population in diffuse gliomas

https://doi.org/10.18632/oncotarget.28553

Raquel Morales-Gallel, María José Ulloa-Navas, Patricia García-Tárraga, Ricardo Prat-Acín, Gaspar Reynés, Pedro Pérez-Borredá, Luis Rubio, Vivian Capilla-González, Jaime Ferrer-Lozano,  and José Manuel García-Verdugo
49-64
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Perspectives

Preclinical and clinical evaluation of the Janus Kinase inhibitor ruxolitinib in multiple myeloma

Preclinical and clinical evaluation of the Janus Kinase inhibitor ruxolitinib in multiple myeloma

https://doi.org/10.18632/oncotarget.28547

Ashley Del Dosso, Elizabeth Tadevosyan,  and James R. Berenson
65-75
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Research Papers

Differential expression of Mad2 gene is consequential to the patterns of histone H3 post-translational modifications in its promoter region in human esophageal cancer samples

Differential expression of Mad2 gene is consequential to the patterns of histone H3 post-translational modifications in its promoter region in human esophageal cancer samples

https://doi.org/10.18632/oncotarget.28554

Chongtham Sovachandra Singh, Nabamita Boruah, Atanu Banerjee, Sillarine Kurkalang, Pooja Swargiary, Hughbert Dakhar,  and Anupam Chatterjee
76-89
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Retraction

Retraction: Long noncoding RNA TUG1 is a diagnostic factor in lung adenocarcinoma and suppresses apoptosis via epigenetic silencing of BAX

Retraction: Long noncoding RNA TUG1 is a diagnostic factor in lung adenocarcinoma and suppresses apoptosis via epigenetic silencing of BAX

https://doi.org/10.18632/oncotarget.28462

Huan Liu, Guizhi Zhou, Xin Fu, Haiyan Cui, Guangrui Pu, Yao Xiao, Wei Sun, Xinhua Dong, Libin Zhang, Sijia Cao, Guiqin Li, Xiaowei Wu,  and Xu Yang
90-90
Retraction  |  PDF  |  How to cite

Research Papers

Genetic and therapeutic landscapes in cohort of pancreatic adenocarcinomas: next-generation sequencing and machine learning for full tumor exome analysis

Genetic and therapeutic landscapes in cohort of pancreatic adenocarcinomas: next-generation sequencing and machine learning for full tumor exome analysis

https://doi.org/10.18632/oncotarget.28512

P.A. Shatalov, N.A. Falaleeva, E.A. Bykova, D.O. Korostin, V.A. Belova, A.A. Zabolotneva, A.P. Shinkarkina, A. Yu Gorbachev, M.B. Potievskiy, V.S. Surkova, Zh V. Khailova, N.A. Kulemin, Denis Baranovskii, A.A. Kostin, A.D. Kaprin,  and P.V. Shegai
91-103
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Corrections

Correction: Targeting programmed cell death ligand 1 by CRISPR/Cas9 in osteosarcoma cells

Correction: Targeting programmed cell death ligand 1 by CRISPR/Cas9 in osteosarcoma cells

https://doi.org/10.18632/oncotarget.28536

Yunfei Liao, Lulu Chen, Yong Feng, Jacson Shen, Yan Gao, Gregory Cote, Edwin Choy, David Harmon, Henry Mankin, Francis Hornicek,  and Zhenfeng Duan
104-105
Correction  |  PDF  |  How to cite

Research Papers

Neurotrophic-tyrosine receptor kinase gene fusion in papillary thyroid cancer: A clinicogenomic biobank and record linkage study from Finland

Neurotrophic-tyrosine receptor kinase gene fusion in papillary thyroid cancer: A clinicogenomic biobank and record linkage study from Finland

https://doi.org/10.18632/oncotarget.28555

Wei Zhang, Arndt A. Schmitz, Roosa E. Kallionpää, Merja Perälä, Niina Pitkänen, Mikko Tukiainen, Erika Alanne, Korinna Jöhrens, Renate Schulze-Rath, Bahman Farahmand,  and Jihong Zong
106-116
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Perspectives

Combining causal and correlative approaches to discover biomarkers of response to paclitaxel

Combining causal and correlative approaches to discover biomarkers of response to paclitaxel

https://doi.org/10.18632/oncotarget.28549

Alberto Moscona-Nissan, Karl J. Habashy, Victor A. Arrieta, Adam M. Sonabend,  and Crismita Dmello
117-122
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Retraction

Retraction: Multimodal targeting of tumor vasculature and cancer stem-like cells in sarcomas with VEGF-A inhibition, HIF-1α inhibition, and hypoxia-activated chemotherapy

Retraction: Multimodal targeting of tumor vasculature and cancer stem-like cells in sarcomas with VEGF-A inhibition, HIF-1α inhibition, and hypoxia-activated chemotherapy

https://doi.org/10.18632/oncotarget.28560

Changhwan Yoon, Kevin K. Chang, Jun Ho Lee, William D. Tap, Charles P. Hart, M. Celeste Simon,  and Sam S. Yoon
123-123
Retraction  |  PDF  |  How to cite

Research Papers

GZ17-6.02 interacts with bexarotene to kill mycosis fungoides cells

GZ17-6.02 interacts with bexarotene to kill mycosis fungoides cells

https://doi.org/10.18632/oncotarget.28557

Michael R. Booth, Laurence Booth, Jane L. Roberts, Cameron West,  and Paul Dent
124-133
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers

Prevalence and spectrum of germline BRCA1 and BRCA2 in a cohort of ovarian cancer patients from the Salento peninsula (Southern Italy): a matter of preventive health

Prevalence and spectrum of germline BRCA1 and BRCA2 in a cohort of ovarian cancer patients from the Salento peninsula (Southern Italy): a matter of preventive health

https://doi.org/10.18632/oncotarget.28561

Elisabetta De Matteis, Maria Rosaria Tumolo, Paolo Tarantino, Mariangela Ciccarese, Tiziana Grassi, Francesco Bagordo, Maria Rita De Giorgio, Emanuele Rizzo,  and Graziana Ronzino
134-141
Abstract  |  PDF  |  Full Text  |  How to cite

Corrections

Correction: Combination treatment with rucaparib (Rubraca) and MDM2 inhibitors, Nutlin-3 and RG7388, has synergistic and dose reduction potential in ovarian cancer

Correction: Combination treatment with rucaparib (Rubraca) and MDM2 inhibitors, Nutlin-3 and RG7388, has synergistic and dose reduction potential in ovarian cancer

https://doi.org/10.18632/oncotarget.28523

Maryam Zanjirband, Nicola Curtin, Richard J. Edmondson,  and John Lunec
142-142
Correction  |  PDF  |  How to cite

Corrections

Correction: YK-4-279 effectively antagonizes EWS-FLI1 induced leukemia in a transgenic mouse model

Correction: YK-4-279 effectively antagonizes EWS-FLI1 induced leukemia in a transgenic mouse model

https://doi.org/10.18632/oncotarget.28524

Tsion Zewdu Minas, Jenny Han, Tahereh Javaheri, Sung-Hyeok Hong, Michaela Schlederer, Yasemin Saygideğer-Kont, Haydar Çelik, Kristina M. Mueller, Idil Temel, Metin Özdemirli, Heinrich Kovar, Hayriye Verda Erkizan, Jeffrey Toretsky, Lukas Kenner, Richard Moriggl,  and Aykut Üren
143-143
Correction  |  PDF  |  How to cite

Research Papers

Sacituzumab govitecan plus platinum-based chemotherapy mediates significant antitumor effects in triple-negative breast, urinary bladder, and small-cell lung carcinomas

Sacituzumab govitecan plus platinum-based chemotherapy mediates significant antitumor effects in triple-negative breast, urinary bladder, and small-cell lung carcinomas

https://doi.org/10.18632/oncotarget.28559

Thomas M. Cardillo, Maria B. Zalath, Roberto Arrojo, Robert M. Sharkey, Serengulam V. Govindan, Chien-Hsing Chang,  and David M. Goldenberg
144-158
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite


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