Oncotarget

Volume 15 (2024)

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Table of Contents

Research Papers

ATR inhibition using gartisertib enhances cell death and synergises with temozolomide and radiation in patient-derived glioblastoma cell lines

ATR inhibition using gartisertib enhances cell death and synergises with temozolomide and radiation in patient-derived glioblastoma cell lines

https://doi.org/10.18632/oncotarget.28551

Mathew Lozinski, Nikola A. Bowden, Moira C. Graves, Michael Fay, Bryan W. Day, Brett W. Stringer,  and Paul A. Tooney
1-18
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Retraction

Retraction: Decreased long intergenic noncoding RNA P7 predicts unfavorable prognosis and promotes tumor proliferation via the modulation of the STAT1-MAPK pathway in hepatocellular carcinoma

Retraction: Decreased long intergenic noncoding RNA P7 predicts unfavorable prognosis and promotes tumor proliferation via the modulation of the STAT1-MAPK pathway in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.28366

Sijie Cheng, Tieling Li, Cheng Wang, Keyu Wang, Chengcai Lai, Jin Yan, Hongxia Fan, Fang Sun, Zhaohai Wang, Peirui Zhang, Linxiang Yu, Zhixian Hong, Guanglin Lei, Baijun Sun, Yuan Gao, Zhaohui Xiao, Xu Ji, Ruilan Wang, Jianzhong Wu, Xiliang Wang, Shaogeng Zhang,  and Penghui Yang
19-19
Retraction  |  PDF  |  How to cite

Research Perspectives

Bone marrow adipocytes provide early sign for progression from MGUS to multiple myeloma

Bone marrow adipocytes provide early sign for progression from MGUS to multiple myeloma

https://doi.org/10.18632/oncotarget.28548

Bilal M. El-Masri, Benedeta Leka, Fatima Mustapha, Michael Tveden Gundesen, Maja Hinge, Thomas Lund, Thomas L. Andersen, Marta Diaz-delCastillo,  and Abbas Jafari
20-26
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Case Reports

Lazarus effect in a patient initially empirically treated with osimertinib for EGFR L858R mutant non-small cell lung cancer with leptomeningeal disease: a case report

Lazarus effect in a patient initially empirically treated with osimertinib for EGFR L858R mutant non-small cell lung cancer with leptomeningeal disease: a case report

https://doi.org/10.18632/oncotarget.28550

Shreya Bhatia, Manuel G. Cortez, Spencer Lessans,  and Wade T. Iams
27-30
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

The fate of drug discovery in academia; dumping in the publication landfill?

The fate of drug discovery in academia; dumping in the publication landfill?

https://doi.org/10.18632/oncotarget.28552

Uzma Saqib, Isaac S. Demaree, Alexander G. Obukhov, Mirza S. Baig, Amiram Ariel,  and Krishnan Hajela
31-34
PDF  |  How to cite  |  Press Release

Retraction

Retraction: Interferon gamma peptidomimetic targeted to interstitial myofibroblasts attenuates renal fibrosis after unilateral ureteral obstruction in mice

Retraction: Interferon gamma peptidomimetic targeted to interstitial myofibroblasts attenuates renal fibrosis after unilateral ureteral obstruction in mice

https://doi.org/10.18632/oncotarget.28532

Fariba Poosti, Ruchi Bansal, Saleh Yazdani, Jai Prakash, Leonie Beljaars, Jacob van den Born, Martin H. de Borst, Harry van Goor, Jan-Luuk Hillebrands,  and Klaas Poelstra
35-35
Retraction  |  PDF  |  How to cite

Research Perspectives

Genetic alterations in thyroid cancer mediating both resistance to BRAF inhibition and anaplastic transformation

Genetic alterations in thyroid cancer mediating both resistance to BRAF inhibition and anaplastic transformation

https://doi.org/10.18632/oncotarget.28544

Mark Lee,  and Luc GT Morris
36-48
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Papers

BCAS1 defines a heterogeneous cell population in diffuse gliomas

BCAS1 defines a heterogeneous cell population in diffuse gliomas

https://doi.org/10.18632/oncotarget.28553

Raquel Morales-Gallel, María José Ulloa-Navas, Patricia García-Tárraga, Ricardo Prat-Acín, Gaspar Reynés, Pedro Pérez-Borredá, Luis Rubio, Vivian Capilla-González, Jaime Ferrer-Lozano,  and José Manuel García-Verdugo
49-64
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Perspectives

Preclinical and clinical evaluation of the Janus Kinase inhibitor ruxolitinib in multiple myeloma

Preclinical and clinical evaluation of the Janus Kinase inhibitor ruxolitinib in multiple myeloma

https://doi.org/10.18632/oncotarget.28547

Ashley Del Dosso, Elizabeth Tadevosyan,  and James R. Berenson
65-75
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Research Papers

Differential expression of Mad2 gene is consequential to the patterns of histone H3 post-translational modifications in its promoter region in human esophageal cancer samples

Differential expression of Mad2 gene is consequential to the patterns of histone H3 post-translational modifications in its promoter region in human esophageal cancer samples

https://doi.org/10.18632/oncotarget.28554

Chongtham Sovachandra Singh, Nabamita Boruah, Atanu Banerjee, Sillarine Kurkalang, Pooja Swargiary, Hughbert Dakhar,  and Anupam Chatterjee
76-89
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Retraction

Retraction: Long noncoding RNA TUG1 is a diagnostic factor in lung adenocarcinoma and suppresses apoptosis via epigenetic silencing of BAX

Retraction: Long noncoding RNA TUG1 is a diagnostic factor in lung adenocarcinoma and suppresses apoptosis via epigenetic silencing of BAX

https://doi.org/10.18632/oncotarget.28462

Huan Liu, Guizhi Zhou, Xin Fu, Haiyan Cui, Guangrui Pu, Yao Xiao, Wei Sun, Xinhua Dong, Libin Zhang, Sijia Cao, Guiqin Li, Xiaowei Wu,  and Xu Yang
90-90
Retraction  |  PDF  |  How to cite

Research Papers

Genetic and therapeutic landscapes in cohort of pancreatic adenocarcinomas: next-generation sequencing and machine learning for full tumor exome analysis

Genetic and therapeutic landscapes in cohort of pancreatic adenocarcinomas: next-generation sequencing and machine learning for full tumor exome analysis

https://doi.org/10.18632/oncotarget.28512

P.A. Shatalov, N.A. Falaleeva, E.A. Bykova, D.O. Korostin, V.A. Belova, A.A. Zabolotneva, A.P. Shinkarkina, A. Yu Gorbachev, M.B. Potievskiy, V.S. Surkova, Zh V. Khailova, N.A. Kulemin, Denis Baranovskii, A.A. Kostin, A.D. Kaprin,  and P.V. Shegai
91-103
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Corrections

Correction: Targeting programmed cell death ligand 1 by CRISPR/Cas9 in osteosarcoma cells

Correction: Targeting programmed cell death ligand 1 by CRISPR/Cas9 in osteosarcoma cells

https://doi.org/10.18632/oncotarget.28536

Yunfei Liao, Lulu Chen, Yong Feng, Jacson Shen, Yan Gao, Gregory Cote, Edwin Choy, David Harmon, Henry Mankin, Francis Hornicek,  and Zhenfeng Duan
104-105
Correction  |  PDF  |  How to cite

Research Papers

Neurotrophic-tyrosine receptor kinase gene fusion in papillary thyroid cancer: A clinicogenomic biobank and record linkage study from Finland

Neurotrophic-tyrosine receptor kinase gene fusion in papillary thyroid cancer: A clinicogenomic biobank and record linkage study from Finland

https://doi.org/10.18632/oncotarget.28555

Wei Zhang, Arndt A. Schmitz, Roosa E. Kallionpää, Merja Perälä, Niina Pitkänen, Mikko Tukiainen, Erika Alanne, Korinna Jöhrens, Renate Schulze-Rath, Bahman Farahmand,  and Jihong Zong
106-116
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Perspectives

Combining causal and correlative approaches to discover biomarkers of response to paclitaxel

Combining causal and correlative approaches to discover biomarkers of response to paclitaxel

https://doi.org/10.18632/oncotarget.28549

Alberto Moscona-Nissan, Karl J. Habashy, Victor A. Arrieta, Adam M. Sonabend,  and Crismita Dmello
117-122
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Retraction

Retraction: Multimodal targeting of tumor vasculature and cancer stem-like cells in sarcomas with VEGF-A inhibition, HIF-1α inhibition, and hypoxia-activated chemotherapy

Retraction: Multimodal targeting of tumor vasculature and cancer stem-like cells in sarcomas with VEGF-A inhibition, HIF-1α inhibition, and hypoxia-activated chemotherapy

https://doi.org/10.18632/oncotarget.28560

Changhwan Yoon, Kevin K. Chang, Jun Ho Lee, William D. Tap, Charles P. Hart, M. Celeste Simon,  and Sam S. Yoon
123-123
Retraction  |  PDF  |  How to cite

Research Papers

GZ17-6.02 interacts with bexarotene to kill mycosis fungoides cells

GZ17-6.02 interacts with bexarotene to kill mycosis fungoides cells

https://doi.org/10.18632/oncotarget.28557

Michael R. Booth, Laurence Booth, Jane L. Roberts, Cameron West,  and Paul Dent
124-133
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Papers

Prevalence and spectrum of germline BRCA1 and BRCA2 in a cohort of ovarian cancer patients from the Salento peninsula (Southern Italy): a matter of preventive health

Prevalence and spectrum of germline BRCA1 and BRCA2 in a cohort of ovarian cancer patients from the Salento peninsula (Southern Italy): a matter of preventive health

https://doi.org/10.18632/oncotarget.28561

Elisabetta De Matteis, Maria Rosaria Tumolo, Paolo Tarantino, Mariangela Ciccarese, Tiziana Grassi, Francesco Bagordo, Maria Rita De Giorgio, Emanuele Rizzo,  and Graziana Ronzino
134-141
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Corrections

Correction: Combination treatment with rucaparib (Rubraca) and MDM2 inhibitors, Nutlin-3 and RG7388, has synergistic and dose reduction potential in ovarian cancer

Correction: Combination treatment with rucaparib (Rubraca) and MDM2 inhibitors, Nutlin-3 and RG7388, has synergistic and dose reduction potential in ovarian cancer

https://doi.org/10.18632/oncotarget.28523

Maryam Zanjirband, Nicola Curtin, Richard J. Edmondson,  and John Lunec
142-142
Correction  |  PDF  |  How to cite

Corrections

Correction: YK-4-279 effectively antagonizes EWS-FLI1 induced leukemia in a transgenic mouse model

Correction: YK-4-279 effectively antagonizes EWS-FLI1 induced leukemia in a transgenic mouse model

https://doi.org/10.18632/oncotarget.28524

Tsion Zewdu Minas, Jenny Han, Tahereh Javaheri, Sung-Hyeok Hong, Michaela Schlederer, Yasemin Saygideğer-Kont, Haydar Çelik, Kristina M. Mueller, Idil Temel, Metin Özdemirli, Heinrich Kovar, Hayriye Verda Erkizan, Jeffrey Toretsky, Lukas Kenner, Richard Moriggl,  and Aykut Üren
143-143
Correction  |  PDF  |  How to cite

Research Papers

Sacituzumab govitecan plus platinum-based chemotherapy mediates significant antitumor effects in triple-negative breast, urinary bladder, and small-cell lung carcinomas

Sacituzumab govitecan plus platinum-based chemotherapy mediates significant antitumor effects in triple-negative breast, urinary bladder, and small-cell lung carcinomas

https://doi.org/10.18632/oncotarget.28559

Thomas M. Cardillo, Maria B. Zalath, Roberto Arrojo, Robert M. Sharkey, Serengulam V. Govindan, Chien-Hsing Chang,  and David M. Goldenberg
144-158
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Papers

GZ17-6.02 interacts with proteasome inhibitors to kill multiple myeloma cells

GZ17-6.02 interacts with proteasome inhibitors to kill multiple myeloma cells

https://doi.org/10.18632/oncotarget.28558

Laurence Booth, Jane L. Roberts, Cameron West,  and Paul Dent
159-174
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Papers

G-quadruplex landscape and its regulation revealed by a new antibody capture method

G-quadruplex landscape and its regulation revealed by a new antibody capture method

https://doi.org/10.18632/oncotarget.28564

Subhamoy Datta, Manthan Patel, Chakkarai Sathyaseelan, Chandrama Ghosh, Akanksha Mudgal, Divyesh Patel, Thenmalarchelvi Rathinavelan,  and Umashankar Singh
175-198
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Corrections

Correction: Sigma-1 and Sigma-2 receptor ligands induce apoptosis and autophagy but have opposite effect on cell proliferation in uveal melanoma

Correction: Sigma-1 and Sigma-2 receptor ligands induce apoptosis and autophagy but have opposite effect on cell proliferation in uveal melanoma

https://doi.org/10.18632/oncotarget.28519

Lucia Longhitano, Carlo Castruccio Castracani, Daniele Tibullo, Roberto Avola, Maria Viola, Giuliano Russo, Orazio Prezzavento, Agostino Marrazzo, Emanuele Amata, Michele Reibaldi, Antonio Longo, Andrea Russo, Nunziatina Laura Parrinello,  and Giovanni Li Volti
199-199
Correction  |  PDF  |  How to cite

Research Papers

Analytical validation of NeXT Personal®, an ultra-sensitive personalized circulating tumor DNA assay

Analytical validation of NeXT Personal®, an ultra-sensitive personalized circulating tumor DNA assay

https://doi.org/10.18632/oncotarget.28565

Josette Northcott, Gabor Bartha, Jason Harris, Conan Li, Fabio C.P. Navarro, Rachel Marty Pyke, Manqing Hong, Qi Zhang, Shuyuan Ma, Tina X. Chen, Janet Lai, Nitin Udar, Juan-Sebastian Saldivar, Erin Ayash, Joshua Anderson, Jiang Li, Tiange Cui, Tu Le, Ruthie Chow, Randy Jerel Velasco, Chris Mallo, Rose Santiago, Robert C. Bruce, Laurie J. Goodman, Yi Chen, Dan Norton, Richard O. Chen,  and John M. Lyle
200-218
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Retraction

Retraction: PDIA6 promotes the proliferation of HeLa cells through activating the Wnt/β-catenin signaling pathway

Retraction: PDIA6 promotes the proliferation of HeLa cells through activating the Wnt/β-catenin signaling pathway

https://doi.org/10.18632/oncotarget.28522

Huijun Gao, Bing Sun, Hailu Fu, Xinming Chi, Faming Wang, Xiaoyu Qi, Jun Hu,  and Shujuan Shao
219-219
Retraction  |  PDF  |  How to cite

Research Papers

ABT199/venetoclax synergism with thiotepa enhances the cytotoxicity of fludarabine, cladribine and busulfan in AML cells

ABT199/venetoclax synergism with thiotepa enhances the cytotoxicity of fludarabine, cladribine and busulfan in AML cells

https://doi.org/10.18632/oncotarget.28563

Benigno C. Valdez, Bin Yuan, David Murray, Jeremy L. Ramdial, Uday Popat, Yago Nieto,  and Borje S. Andersson
220-231
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Research Perspectives

From osimertinib to preemptive combinations

From osimertinib to preemptive combinations

https://doi.org/10.18632/oncotarget.28569

Mikhail V. Blagosklonny
232-237
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Research Papers

Durvalumab and tremelimumab before surgery in patients with hormone receptor positive, HER2-negative stage II–III breast cancer

Durvalumab and tremelimumab before surgery in patients with hormone receptor positive, HER2-negative stage II–III breast cancer

https://doi.org/10.18632/oncotarget.28567

Haven R. Garber, Sreyashi Basu, Sonali Jindal, Zhong He, Khoi Chu, Akshara Singareeka Raghavendra, Clinton Yam, Lumarie Santiago, Beatriz E. Adrada, Padmanee Sharma, Elizabeth A. Mittendorf,  and Jennifer K. Litton
238-247
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Papers

Exploring the role of GHRH antagonist MIA-602 in overcoming Doxorubicin-resistance in acute myeloid leukemia

Exploring the role of GHRH antagonist MIA-602 in overcoming Doxorubicin-resistance in acute myeloid leukemia

https://doi.org/10.18632/oncotarget.28579

Simonetta I. Gaumond, Rama Abdin, Joel Costoya, Andrew V. Schally,  and Joaquin J. Jimenez
248-254
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Retraction

Retraction: Knockdown of NEAT1 restrained the malignant progression of glioma stem cells by activating microRNA let-7e

Retraction: Knockdown of NEAT1 restrained the malignant progression of glioma stem cells by activating microRNA let-7e

https://doi.org/10.18632/oncotarget.28568

Wei Gong, Jian Zheng, Xiaobai Liu, Jun Ma, Yunhui Liu,  and Yixue Xue
255-255
Retraction  |  PDF  |  How to cite

Research Papers

Novel therapeutic bispecific antibodies for B-cell lymphoma targeting IgM and other antigens on the B-cell surface

Novel therapeutic bispecific antibodies for B-cell lymphoma targeting IgM and other antigens on the B-cell surface

https://doi.org/10.18632/oncotarget.28578

Takahiro Ohashi, Sayuri Terada, Shinsuke Hiramoto, Yuko Nagata, Hirokazu Suzuki, Hitoshi Miyashita, Tetsuo Sasaki, Yasukatsu Tsukada,  and Keiko Fukushima
256-274
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Papers

Transfected SARS-CoV-2 spike DNA for mammalian cell expression inhibits p53 activation of p21(WAF1), TRAIL Death Receptor DR5 and MDM2 proteins in cancer cells and increases cancer cell viability after chemotherapy exposure

Transfected SARS-CoV-2 spike DNA for mammalian cell expression inhibits p53 activation of p21(WAF1), TRAIL Death Receptor DR5 and MDM2 proteins in cancer cells and increases cancer cell viability after chemotherapy exposure

https://doi.org/10.18632/oncotarget.28582

Shengliang Zhang,  and Wafik S. El-Deiry
275-284
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Corrections

Correction: Gap junction-mediated transfer of miR-145-5p from microvascular endothelial cells to colon cancer cells inhibits angiogenesis

Correction: Gap junction-mediated transfer of miR-145-5p from microvascular endothelial cells to colon cancer cells inhibits angiogenesis

https://doi.org/10.18632/oncotarget.28528

Dominique Thuringer, Gaetan Jego, Kevin Berthenet, Arlette Hammann, Eric Solary,  and Carmen Garrido
285-287
Correction  |  PDF  |  How to cite

Research Papers

Deep learning-based whole-body PSMA PET/CT attenuation correction utilizing Pix-2-Pix GAN

Deep learning-based whole-body PSMA PET/CT attenuation correction utilizing Pix-2-Pix GAN

https://doi.org/10.18632/oncotarget.28583

Kevin C. Ma, Esther Mena, Liza Lindenberg, Nathan S. Lay, Phillip Eclarinal, Deborah E. Citrin, Peter A. Pinto, Bradford J. Wood, William L. Dahut, James L. Gulley, Ravi A. Madan, Peter L. Choyke, Ismail Baris Turkbey,  and Stephanie A. Harmon
288-300
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Retraction

Retraction: Chronically high level of tgfb1a induction causes both hepatocellular carcinoma and cholangiocarcinoma via a dominant Erk pathway in zebrafish

Retraction: Chronically high level of tgfb1a induction causes both hepatocellular carcinoma and cholangiocarcinoma via a dominant Erk pathway in zebrafish

https://doi.org/10.18632/oncotarget.28570

Chuan Yan, Qiqi Yang, Han-Ming Shen, Jan M. Spitsbergen,  and Zhiyuan Gong
301-301
Retraction  |  PDF  |  How to cite

Research Papers

Cyclin D1 expression in penile cancer

Cyclin D1 expression in penile cancer

https://doi.org/10.18632/oncotarget.28584

Wesliany Everton Duarte, Jaqueline Diniz Pinho, Syomara Pereira da Costa Melo, Denner Rodrigo Diniz Duarte, Juliana Martins da Guia Ribeiro do Carmo, André Salim Khayat, José Ribamar Rodrigues Calixto, Marcos Adriano Garcia Campos, Rita da Graça Carvalhal Frazão Correa, Antonio Machado Alencar Júnior, Antônio Augusto Lima Teixeira-Júnior,  and Gyl Eanes Barros Silva
302-311
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Retraction

Retraction: Knockdown of TRIM65 inhibits lung cancer cell proliferation, migration and invasion: A therapeutic target in human lung cancer

Retraction: Knockdown of TRIM65 inhibits lung cancer cell proliferation, migration and invasion: A therapeutic target in human lung cancer

https://doi.org/10.18632/oncotarget.28571

Xiao-Lin Wang, Wei-Ping Shi, Hong-Can Shi, Shi-Chun Lu, Kang Wang, Chao Sun, Jian-Sheng He, Wei-Guo Jin, Xiao-Xia Lv, Hui Zou,  and Yu-Sheng Shu
312-312
Retraction  |  PDF  |  How to cite

Research Papers

The anticancer potential of the CLK kinases inhibitors 1C8 and GPS167 revealed by their impact on the epithelial-mesenchymal transition and the antiviral immune response

The anticancer potential of the CLK kinases inhibitors 1C8 and GPS167 revealed by their impact on the epithelial-mesenchymal transition and the antiviral immune response

https://doi.org/10.18632/oncotarget.28585

Lulzim Shkreta, Johanne Toutant, Aurélie Delannoy, David Durantel, Anna Salvetti, Sophie Ehresmann, Martin Sauvageau, Julien A. Delbrouck, Alice Gravel-Trudeau, Christian Comeau, Caroline Huard, Jasmin Coulombe-Huntington, Mike Tyers, David Grierson, Pierre-Luc Boudreault,  and Benoit Chabot
313-325
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Video Interview

Corrections

Correction: Reduced miR-200b and miR-200c expression contributes to abnormal hepatic lipid accumulation by stimulating JUN expression and activating the transcription of srebp1

Correction: Reduced miR-200b and miR-200c expression contributes to abnormal hepatic lipid accumulation by stimulating JUN expression and activating the transcription of srebp1

https://doi.org/10.18632/oncotarget.28562

Jun Guo, Weiwei Fang, Libo Sun, Yonggang Lu, Lin Dou, Xiuqing Huang, Mingxiao Sun, Cheng Pang, Jing Qu, Guanghui Liu,  and Jian Li
326-327
Correction  |  PDF  |  How to cite

Research Papers

GZ17-6.02 kills PDX isolates of uveal melanoma

GZ17-6.02 kills PDX isolates of uveal melanoma

https://doi.org/10.18632/oncotarget.28586

Laurence Booth, Jane L. Roberts, Ivan Spasojevic, Kaitlyn C. Baker, Andrew Poklepovic, Cameron West, John M. Kirkwood,  and Paul Dent
328-344
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Reviews

The importance of integrated therapies on cancer: Silibinin, an old and new molecule

The importance of integrated therapies on cancer: Silibinin, an old and new molecule

https://doi.org/10.18632/oncotarget.28587

Elisa Roca, Giuseppe Colloca, Fiorella Lombardo, Andrea Bellieni, Alessandra Cucinella, Giorgio Madonia, Licia Martinelli, Maria Elisa Damiani, Ilaria Zampieri,  and Antonio Santo
345-353
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Retraction

Retraction: Acquired resistance to BRAFi reverses senescence-like phenotype in mutant BRAF melanoma

Retraction: Acquired resistance to BRAFi reverses senescence-like phenotype in mutant BRAF melanoma

https://doi.org/10.18632/oncotarget.28580

Mohammad Krayem, Ahmad Najem, Fabrice Journe, Renato Morandini, François Sales, Ahmad Awada,  and Ghanem E. Ghanem
354-354
Retraction  |  PDF  |  How to cite

Research Perspectives

Bruton’s tyrosine kinase inhibitor-related cardiotoxicity: The quest for predictive biomarkers and improved risk stratification

Bruton’s tyrosine kinase inhibitor-related cardiotoxicity: The quest for predictive biomarkers and improved risk stratification

https://doi.org/10.18632/oncotarget.28589

Jai N. Patel, Jai Singh,  and Nilanjan Ghosh
355-359
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Retraction

Retraction: Long non-coding RNA H19 induces hippocampal neuronal apoptosis via Wnt signaling in a streptozotocin-induced rat model of diabetes mellitus

Retraction: Long non-coding RNA H19 induces hippocampal neuronal apoptosis via Wnt signaling in a streptozotocin-induced rat model of diabetes mellitus

https://doi.org/10.18632/oncotarget.28576

Yu-Hao Zhao, Tie-Feng Ji, Qi Luo,  and Jin-Lu Yu
360-360
Retraction  |  PDF  |  How to cite

Research Papers

Synergistic cytotoxicity of histone deacetylase and poly-ADP ribose polymerase inhibitors and decitabine in pancreatic cancer cells: Implications for novel therapy

Synergistic cytotoxicity of histone deacetylase and poly-ADP ribose polymerase inhibitors and decitabine in pancreatic cancer cells: Implications for novel therapy

https://doi.org/10.18632/oncotarget.28588

Benigno C. Valdez, Apostolia M. Tsimberidou, Bin Yuan, Yago Nieto, Mehmet A. Baysal, Abhijit Chakraborty, Clark R. Andersen,  and Borje S. Andersson
361-373
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Perspectives

When does a melanoma metastasize? Implications for management

When does a melanoma metastasize? Implications for management

https://doi.org/10.18632/oncotarget.28591

John F. Thompson,  and Gabrielle J. Williams
374-378
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Corrections

Correction: FOXC1 promotes melanoma by activating MST1R/PI3K/AKT pathway and is associated with poor prognosis in melanoma

Correction: FOXC1 promotes melanoma by activating MST1R/PI3K/AKT pathway and is associated with poor prognosis in melanoma

https://doi.org/10.18632/oncotarget.28590

Jinhua Wang, Li Li, Shiwei Liu, Ying Zhao, Lin Wang,  and Guanhua Du
379-380
Correction  |  PDF  |  How to cite

Research Papers

Assessment of serum tumor markers CEA, CA-125, and CA19-9 as adjuncts in non-small cell lung cancer management

Assessment of serum tumor markers CEA, CA-125, and CA19-9 as adjuncts in non-small cell lung cancer management

https://doi.org/10.18632/oncotarget.28566

Scott Strum, Mark Vincent, Meghan Gipson, Eric McArthur,  and Daniel Breadner
381-388
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

Leveraging gold nanostars for precision laser interstitial thermal therapy

Leveraging gold nanostars for precision laser interstitial thermal therapy

https://doi.org/10.18632/oncotarget.28592

Aden P. Haskell-Mendoza, Ethan S. Srinivasan, Tuan Vo-Dinh,  and Peter E. Fecci
389-391
PDF  |  How to cite  |  Press Release

Research Perspectives

Starving cancer cells to enhance DNA damage and immunotherapy response

Starving cancer cells to enhance DNA damage and immunotherapy response

https://doi.org/10.18632/oncotarget.28595

Aashirwad Shahi,  and Dawit Kidane
392-399
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

Genomics has more to reveal

Genomics has more to reveal

https://doi.org/10.18632/oncotarget.28596

Laurène Fenwarth,  and Nicolas Duployez
400-401
PDF  |  How to cite  |  Press Release

Retraction

Retraction: Hypoxia-inducible factor 1a induces phenotype switch of human aortic vascular smooth muscle cell through PI3K/AKT/AEG-1 signaling

Retraction: Hypoxia-inducible factor 1a induces phenotype switch of human aortic vascular smooth muscle cell through PI3K/AKT/AEG-1 signaling

https://doi.org/10.18632/oncotarget.28575

Kai Liu, Changcun Fang, Yuwen Shen, Zhengqin Liu, Min Zhang, Bingbing Ma,  and Xinyan Pang
402-402
Retraction  |  PDF  |  How to cite

Editorial

Targeting ABC transporters in PDAC – past, present, or future?

Targeting ABC transporters in PDAC – past, present, or future?

https://doi.org/10.18632/oncotarget.28597

Cecilia Bergonzini, Elisa Giovannetti,  and Erik H.J. Danen
403-406
PDF  |  How to cite  |  Press Release

Corrections

Correction: Analytical validation of NeXT Personal®, an ultra-sensitive personalized circulating tumor DNA assay

Correction: Analytical validation of NeXT Personal®, an ultra-sensitive personalized circulating tumor DNA assay

https://doi.org/10.18632/oncotarget.28581

Josette Northcott, Gabor Bartha, Jason Harris, Conan Li, Fabio C.P. Navarro, Rachel Marty Pyke, Manqing Hong, Qi Zhang, Shuyuan Ma, Tina X. Chen, Janet Lai, Nitin Udar, Juan-Sebastian Saldivar, Erin Ayash, Joshua Anderson, Jiang Li, Tiange Cui, Tu Le, Ruthie Chow, Randy Jerel Velasco, Chris Mallo, Rose Santiago, Robert C. Bruce, Laurie J. Goodman, Yi Chen, Dan Norton, Richard O. Chen,  and John M. Lyle
407-407
Correction  |  PDF  |  How to cite

Research Papers

Comparison of FDG-PET/CT and CT for evaluation of tumor response to nivolumab plus ipilimumab combination therapy and prognosis prediction in patients with unresectable malignant pleural mesothelioma

Comparison of FDG-PET/CT and CT for evaluation of tumor response to nivolumab plus ipilimumab combination therapy and prognosis prediction in patients with unresectable malignant pleural mesothelioma

https://doi.org/10.18632/oncotarget.28594

Kazuhiro Kitajima, Kozo Kuribayashi, Toshiyuki Minami, Hiroyuki Yokoyama, Akifumi Nakamura, Masaki Hashimoto, Takashi Kijima, Seiki Hasegawa, Hayato Kaida,  and Koichiro Yamakado
408-417
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

HER2-low and HER2-zero in breast cancer between prognosis, prediction and entity

HER2-low and HER2-zero in breast cancer between prognosis, prediction and entity

https://doi.org/10.18632/oncotarget.28598

Marcus Schmidt, Hans-Anton Lehr,  and Katrin Almstedt
418-420
PDF  |  How to cite  |  Press Release

Editorial

Using early on-treatment circulating tumor DNA measurements as response assessment in metastatic castration resistant prostate cancer

Using early on-treatment circulating tumor DNA measurements as response assessment in metastatic castration resistant prostate cancer

https://doi.org/10.18632/oncotarget.28599

S.H. Tolmeijer, E. Boerrigter, N.P. Van Erp,  and Niven Mehra
421-423
PDF  |  How to cite  |  Press Release

Research Papers

Regorafenib synergizes with TAS102 against multiple gastrointestinal cancers and overcomes cancer stemness, trifluridine-induced angiogenesis, ERK1/2 and STAT3 signaling regardless of KRAS or BRAF mutational status

Regorafenib synergizes with TAS102 against multiple gastrointestinal cancers and overcomes cancer stemness, trifluridine-induced angiogenesis, ERK1/2 and STAT3 signaling regardless of KRAS or BRAF mutational status

https://doi.org/10.18632/oncotarget.28602

Jun Zhang, Lanlan Zhou, Shuai Zhao,  and Wafik S. El-Deiry
424-438
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Corrections

Correction: BALB/c mice immunized with a combination of virus-like particles incorporating Kaposi sarcoma-associated herpesvirus (KSHV) envelope glycoproteins gpK8.1, gB, and gH/gL induced comparable serum neutralizing antibody activity to UV-inactivated KSHV

Correction: BALB/c mice immunized with a combination of virus-like particles incorporating Kaposi sarcoma-associated herpesvirus (KSHV) envelope glycoproteins gpK8.1, gB, and gH/gL induced comparable serum neutralizing antibody activity to UV-inactivated KSHV

https://doi.org/10.18632/oncotarget.28600

Anne K. Barasa, Peng Ye, Meredith Phelps, Ganapathiram T. Arivudainambi, Timelia Tison,  and Javier Gordon Ogembo
439-440
Correction  |  PDF  |  How to cite

Corrections

Correction: Real time ex vivo chemosensitivity assay for pancreatic adenocarcinoma

Correction: Real time ex vivo chemosensitivity assay for pancreatic adenocarcinoma

https://doi.org/10.18632/oncotarget.28556

Dae Won Kim, Francisca Beato, Youngchul Kim, Alexandra F. Tassielli, Ruifan Dai, Jason W. Denbo, Pamela J. Hodul, Mokenge P. Malafa,  and Jason B. Fleming
441-441
Correction  |  PDF  |  How to cite

Editorial

DDX41 and its unique contribution to myeloid leukemogenesis

DDX41 and its unique contribution to myeloid leukemogenesis

https://doi.org/10.18632/oncotarget.28603

Hirotaka Matsui
442-443
PDF  |  How to cite  |  Press Release

Research Papers

Improved efficacy of pembrolizumab combined with soluble EphB4-albumin in HPV-negative EphrinB2 positive head neck squamous cell carcinoma

Improved efficacy of pembrolizumab combined with soluble EphB4-albumin in HPV-negative EphrinB2 positive head neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.28605

Alexandra Jackovich, Barbara J. Gitlitz, Justin Wayne Wong Tiu-lim, Vinay Duddalwar, Kevin George King, Anthony B. El-Khoueiry, Jacob Stephen Thomas, Denice Tsao-Wei, David I. Quinn, Parkash S. Gill,  and Jorge J. Nieva
444-458
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

Genotype matters: Personalized screening recommendations for germline CHEK2 variants

Genotype matters: Personalized screening recommendations for germline CHEK2 variants

https://doi.org/10.18632/oncotarget.28604

Adela Rodriguez Hernandez, Rochelle Scheib, Judy E. Garber, Huma Q. Rana,  and Brittany L. Bychkovsky
459-460
PDF  |  How to cite  |  Press Release

Retraction

Retraction: Superior efficacy of the antifungal agent ciclopirox olamine over gemcitabine in pancreatic cancer models

Retraction: Superior efficacy of the antifungal agent ciclopirox olamine over gemcitabine in pancreatic cancer models

https://doi.org/10.18632/oncotarget.28601

Chrysovalantou Mihailidou, Pavlos Papakotoulas, Athanasios G. Papavassiliou,  and Michalis V. Karamouzis
461-461
Retraction  |  PDF  |  How to cite

Editorial

The advances in targeting CD47/SIRPα “do not eat me” axis and their ongoing challenges as an anticancer therapy

The advances in targeting CD47/SIRPα “do not eat me” axis and their ongoing challenges as an anticancer therapy

https://doi.org/10.18632/oncotarget.28607

Maria Gracia-Hernandez, Manasa Suresh,  and Alejandro Villagra
462-465
PDF  |  How to cite  |  Press Release

Editorial

How to deal with runaway metastatic disease?

How to deal with runaway metastatic disease?

https://doi.org/10.18632/oncotarget.28609

Justine Paris,  and Guilhem Bousquet
466-467
PDF  |  How to cite  |  Press Release

Corrections

Correction: Cyclin E/Cdk2-dependent phosphorylation of Mcl-1 determines its stability and cellular sensitivity to BH3 mimetics

Correction: Cyclin E/Cdk2-dependent phosphorylation of Mcl-1 determines its stability and cellular sensitivity to BH3 mimetics

https://doi.org/10.18632/oncotarget.28593

Gaurav S. Choudhary, Trinh T. Tat, Saurav Misra, Brian T. Hill, Mitchell R. Smith, Alexandru Almasan,  and Suparna Mazumder
468-469
Correction  |  PDF  |  How to cite

Research Papers

INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death

INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death

https://doi.org/10.18632/oncotarget.28608

Chantal L. Duurland, Thijs de Gunst, Harm C. den Boer, Marion T.J. van den Bosch, Bryony J. Telford, Rogier M. Vos, Xiaolei Xie, Mingfa Zang, Fang Wang, Yingying Shao, Xiaoyu An, Jingjing Wang, Jie Cai, Ludovic Bourré, Laurens A.H. van Pinxteren, Roel Q.J. Schaapveld, Michel Janicot,  and Sanaz Yahyanejad
470-485
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Perspectives

Targeting the multifaceted BRAF in cancer: New directions

Targeting the multifaceted BRAF in cancer: New directions

https://doi.org/10.18632/oncotarget.28612

Eamon Toye, Alexander Chehrazi-Raffle, Justin Hwang,  and Emmanuel S. Antonarakis
486-492
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Case Reports

Rapid but nondurable response of a BRAF exon 15 double-mutated spindle cell sarcoma to a combination of BRAF and MEK inhibitors

Rapid but nondurable response of a BRAF exon 15 double-mutated spindle cell sarcoma to a combination of BRAF and MEK inhibitors

https://doi.org/10.18632/oncotarget.28606

Kseniya Sinichenkova, Iliya Sidorov, Nataliya Kriventsova, Dmitriy Konovalov, Ruslan Abasov, Nataliya Usman, Alexander Karachunskiy, Galina Novichkova, Dmitriy Litvinov,  and Alexander Druy
493-500
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

Strategies to disrupt NKG2A:HLA-E interactions for improved anti-cancer immunity

Strategies to disrupt NKG2A:HLA-E interactions for improved anti-cancer immunity

https://doi.org/10.18632/oncotarget.28610

Jack G. Fisher, Lara V. Graham,  and Matthew D. Blunt
501-503
PDF  |  How to cite  |  Press Release

Corrections

Correction: Aspirin counteracts cancer stem cell features, desmoplasia and gemcitabine resistance in pancreatic cancer

Correction: Aspirin counteracts cancer stem cell features, desmoplasia and gemcitabine resistance in pancreatic cancer

https://doi.org/10.18632/oncotarget.28527

Yiyao Zhang, Li Liu, Pei Fan, Nathalie Bauer, Jury Gladkich, Eduard Ryschich, Alexandr V. Bazhin, Nathalia A. Giese, Oliver Strobel, Thilo Hackert, Ulf Hinz, Wolfgang Gross, Franco Fortunato,  and Ingrid Herr
504-506
Correction  |  PDF  |  How to cite

Research Papers

Prognostic and therapeutic insights into MIF, DDT, and CD74 in melanoma

Prognostic and therapeutic insights into MIF, DDT, and CD74 in melanoma

https://doi.org/10.18632/oncotarget.28615

Caroline Naomi Valdez, Gabriela Athziri Sánchez-Zuno, Lais Osmani, Wael Ibrahim, Anjela Galan, Antonietta Bacchiocchi, Ruth Halaban, Rajan P. Kulkarni, Insoo Kang, Richard Bucala,  and Thuy Tran
507-520
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Papers

Prevalence and impact of the KIT M541L variant in patients with mastocytosis

Prevalence and impact of the KIT M541L variant in patients with mastocytosis

https://doi.org/10.18632/oncotarget.28614

Luisa N. Dominguez Aldama, Eric Karlins, Xiaoping Sun, Daniel Veltri, Hirsh D. Komarow, Irina Maric, Dean D. Metcalfe,  and Melody C. Carter
521-531
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Editorial

Beyond pixels: Graph filtration learning unveils new dimensions in hepatocellular carcinoma imaging

Beyond pixels: Graph filtration learning unveils new dimensions in hepatocellular carcinoma imaging

https://doi.org/10.18632/oncotarget.28635

Yashbir Singh
532-534
PDF  |  How to cite  |  Press Release

Reviews

Targeting WNT5B and WNT10B in osteosarcoma

Targeting WNT5B and WNT10B in osteosarcoma

https://doi.org/10.18632/oncotarget.28617

Gustavo A. Miranda-Carboni,  and Susan A. Krum
535-540
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Retraction

Retraction: Berberine and cinnamaldehyde together prevent lung carcinogenesis

Retraction: Berberine and cinnamaldehyde together prevent lung carcinogenesis

https://doi.org/10.18632/oncotarget.28577

Mingjing Meng, Shengnan Geng, Zhenhua Du, Jingjing Yao, Yaqiu Zheng, Zibo Li, Zhenzhen Zhang, Jiahuan Li, Yongjian Duan,  and Gangjun Du
541-541
Retraction  |  PDF  |  How to cite

Retraction

Retraction: CUL4B promotes bladder cancer metastasis and induces epithelial-to-mesenchymal transition by activating the Wnt/β-catenin signaling pathway

Retraction: CUL4B promotes bladder cancer metastasis and induces epithelial-to-mesenchymal transition by activating the Wnt/β-catenin signaling pathway

https://doi.org/10.18632/oncotarget.28407

Xia-Wa Mao, Jia-Quan Xiao, Gang Xu, Zhong-Yi Li, Hui-Feng Wu, Yi Li, Yi-Chun Zheng,  and Nan Zhang
542-542
Retraction  |  PDF  |  How to cite

Editorial

Next-generation vaccines are showing promise against glioblastoma

Next-generation vaccines are showing promise against glioblastoma

https://doi.org/10.18632/oncotarget.28636

Robert O. Dillman,  and Daniela A. Bota
543-548
PDF  |  How to cite  |  Press Release

Retraction

Retraction: IGF-1 induces the epithelial-mesenchymal transition via Stat5 in hepatocellular carcinoma

Retraction: IGF-1 induces the epithelial-mesenchymal transition via Stat5 in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.28573

Chuanzong Zhao, Qian Wang, Ben Wang, Qi Sun, Zhaobin He, Jianguo Hong, Florian Kuehn, Enyu Liu,  and Zongli Zhang
549-549
Retraction  |  PDF  |  How to cite

Research Papers

Chemical complementarity of tumor resident, T-cell receptor CDR3s and renalase-1 correlates with increased melanoma survival

Chemical complementarity of tumor resident, T-cell receptor CDR3s and renalase-1 correlates with increased melanoma survival

https://doi.org/10.18632/oncotarget.28633

Saif Zaman, Fred S. Gorelick, Andrea Chrobrutskiy, Boris I. Chobrutskiy, Gary V. Desir,  and George Blanck
550-561
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Reviews

The gut barrier as a gatekeeper in colorectal cancer treatment

The gut barrier as a gatekeeper in colorectal cancer treatment

https://doi.org/10.18632/oncotarget.28634

Roy Hajjar, Carole Richard,  and Manuela M. Santos
562-572
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Retraction

Retraction: The crucial role of SRPK1 in IGF-1-induced EMT of human gastric cancer

Retraction: The crucial role of SRPK1 in IGF-1-induced EMT of human gastric cancer

https://doi.org/10.18632/oncotarget.28431

Hong Wang, Chunlei Wang, Wenling Tian,  and Yanfen Yao
573-573
Retraction  |  PDF  |  How to cite

Retraction

Retraction: In vivo and in vitro effects of microRNA-27a on proliferation, migration and invasion of breast cancer cells through targeting of SFRP1 gene via Wnt/β-catenin signaling pathway

Retraction: In vivo and in vitro effects of microRNA-27a on proliferation, migration and invasion of breast cancer cells through targeting of SFRP1 gene via Wnt/β-catenin signaling pathway

https://doi.org/10.18632/oncotarget.28616

Ling-Yu Kong, Mei Xue, Qing-Cai Zhang,  and Chuan-Fu Su
574-574
Retraction  |  PDF  |  How to cite

Research Papers

A nanobody against the V-ATPase c subunit inhibits metastasis of 4T1-12B breast tumor cells to lung in mice

A nanobody against the V-ATPase c subunit inhibits metastasis of 4T1-12B breast tumor cells to lung in mice

https://doi.org/10.18632/oncotarget.28638

Zhen Li, Mohammed A. Alshagawi, Rebecca A. Oot, Mariam K. Alamoudi, Kevin Su, Wenhui Li, Michael P. Collins, Stephan Wilkens,  and Michael Forgac
575-587
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

Artificial intelligence: A transformative tool in precision oncology

Artificial intelligence: A transformative tool in precision oncology

https://doi.org/10.18632/oncotarget.28639

Jeremy McGale, Matthew J. Liao, Egesta Lopci, Aurélien Marabelle,  and Laurent Dercle
588-589
PDF  |  How to cite  |  Press Release

Retraction

Retraction: MicroRNA-138 acts as a tumor suppressor in non small cell lung cancer via targeting YAP1

Retraction: MicroRNA-138 acts as a tumor suppressor in non small cell lung cancer via targeting YAP1

https://doi.org/10.18632/oncotarget.28645

Ling Xiao, Hui Zhou, Xiang-Ping Li, Juan Chen, Chao Fang, Chen-Xue Mao, Jia-Jia Cui, Wei Zhang, Hong-Hao Zhou, Ji-Ye Yin,  and Zhao-Qian Liu
590-590
Retraction  |  PDF  |  How to cite

Research Papers

Inhibition of miR-10b treats metastatic breast cancer by targeting stem cell-like properties

Inhibition of miR-10b treats metastatic breast cancer by targeting stem cell-like properties

https://doi.org/10.18632/oncotarget.28641

Alan Halim, Nasreen Al-Qadi, Elizabeth Kenyon, Kayla N. Conner, Sujan Kumar Mondal, Zdravka Medarova,  and Anna Moore
591-606
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Editorial

Generative AI in oncological imaging: Revolutionizing cancer detection and diagnosis

Generative AI in oncological imaging: Revolutionizing cancer detection and diagnosis

https://doi.org/10.18632/oncotarget.28640

Yashbir Singh, Quincy A. Hathaway,  and Bradley J. Erickson
607-608
PDF  |  How to cite  |  Press Release

Research Perspectives

Trained and ready - the case for an inflammatory memory for hematopoietic stem and progenitor cells in the AML niche

Trained and ready - the case for an inflammatory memory for hematopoietic stem and progenitor cells in the AML niche

https://doi.org/10.18632/oncotarget.28642

Ding-Wen Chen, Eric K. Wafula,  and Peter Kurre
609-613
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Research Papers

Integrated stress response (ISR) activation and apoptosis through HRI kinase by PG3 and other p53 pathway-restoring cancer therapeutics

Integrated stress response (ISR) activation and apoptosis through HRI kinase by PG3 and other p53 pathway-restoring cancer therapeutics

https://doi.org/10.18632/oncotarget.28637

Xiaobing Tian,  and Wafik S. El-Deiry
614-633
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Retraction

Retraction: Myeloid ecotropic viral integration site 1 inhibits cell proliferation, invasion or migration in human gastric cancer

Retraction: Myeloid ecotropic viral integration site 1 inhibits cell proliferation, invasion or migration in human gastric cancer

https://doi.org/10.18632/oncotarget.28649

Fei Song, Hong Wang,  and Yingying Wang
634-634
Retraction  |  PDF  |  How to cite

Editorial

The emerging role of AI in enhancing intratumoral immunotherapy care

The emerging role of AI in enhancing intratumoral immunotherapy care

https://doi.org/10.18632/oncotarget.28643

Abin Sajan, Abdallah Lamane, Asad Baig, Korentin Le Floch,  and Laurent Dercle
635-637
PDF  |  How to cite  |  Press Release

Mini-Review

Linking FOXM1 and PD-L1 to CDK4/6-MEK targeted therapy resistance in malignant peripheral nerve sheath tumors

Linking FOXM1 and PD-L1 to CDK4/6-MEK targeted therapy resistance in malignant peripheral nerve sheath tumors

https://doi.org/10.18632/oncotarget.28650

Joshua J. Lingo, Ellen Voigt,  and Dawn E. Quelle
638-643
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Research Perspectives

UBA1 dysfunction in VEXAS and cancer

UBA1 dysfunction in VEXAS and cancer

https://doi.org/10.18632/oncotarget.28646

Maki Sakuma, Torsten Haferlach,  and Wencke Walter
644-658
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Retraction

Retraction: Association study of inflammatory cytokine and chemokine expression in hand foot and mouth disease

Retraction: Association study of inflammatory cytokine and chemokine expression in hand foot and mouth disease

https://doi.org/10.18632/oncotarget.28655

Wenzhong Shang, Suying Qian, Lijuan Fang, Yong Han,  and Cuiping Zheng
659-659
Retraction  |  PDF  |  How to cite

Editorial

Lessons from the ACDC-RP trial: Clinical trial design for radical prostatectomy neoadjuvant therapy trials

Lessons from the ACDC-RP trial: Clinical trial design for radical prostatectomy neoadjuvant therapy trials

https://doi.org/10.18632/oncotarget.28648

Rashid K. Sayyid,  and Neil E. Fleshner
660-661
PDF  |  How to cite  |  Press Release

Reviews

Zika virus and brain cancer: Can Zika be an effective treatment for brain cancer? A systematic review

Zika virus and brain cancer: Can Zika be an effective treatment for brain cancer? A systematic review

https://doi.org/10.18632/oncotarget.28647

Mateus Gonçalves de Sena Barbosa, Beatriz Rodrigues Messias, Rafael Trindade Tatit, Maycon Cristian Gomes de Paula, Valdecir Boeno Spenazato Júnior, Maria Gabriella Borges Braga, Caio Vinícius Marcolino Santos, Luiza D'Ottaviano Cobos, Vinícius Otávio da Silva, Eberval Gadelha Figueiredo, Nicollas Nunes Rabelo,  and Bipin Chaurasia
662-673
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

Transplant or no transplant for TP53 mutated AML

Transplant or no transplant for TP53 mutated AML

https://doi.org/10.18632/oncotarget.28652

Talha Badar, Moazzam Shahzad, Ehab Atallah, Mark R. Litzow,  and Mohamed A. Kharfan-Dabaja
674-676
PDF  |  How to cite  |  Press Release

Corrections

Correction: Niclosamide enhances abiraterone treatment via inhibition of androgen receptor variants in castration resistant prostate cancer

Correction: Niclosamide enhances abiraterone treatment via inhibition of androgen receptor variants in castration resistant prostate cancer

https://doi.org/10.18632/oncotarget.28656

Chengfei Liu, Cameron Armstrong, Yezi Zhu, Wei Lou,  and Allen C. Gao
677-678
Correction  |  PDF  |  How to cite

Reviews

Molecular chaperones: Guardians of tumor suppressor stability and function

Molecular chaperones: Guardians of tumor suppressor stability and function

https://doi.org/10.18632/oncotarget.28653

Jennifer A. Heritz, Sarah J. Backe,,  and Mehdi Mollapour
679-696
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release  |  Video Interview

Corrections

Correction: Suppression of progranulin expression inhibits bladder cancer growth and sensitizes cancer cells to cisplatin

Correction: Suppression of progranulin expression inhibits bladder cancer growth and sensitizes cancer cells to cisplatin

https://doi.org/10.18632/oncotarget.28657

Simone Buraschi, Shi-Qiong Xu, Manuela Stefanello, Igor Moskalev, Alaide Morcavallo, Marco Genua, Ryuta Tanimoto, Ruth Birbe, Stephen C. Peiper, Leonard G. Gomella, Antonino Belfiore, Peter C. Black, Renato V. Iozzo,  and Andrea Morrione
697-698
Correction  |  PDF  |  How to cite

Research Papers

Next-generation cell-penetrating antibodies for tumor targeting and RAD51 inhibition

Next-generation cell-penetrating antibodies for tumor targeting and RAD51 inhibition

https://doi.org/10.18632/oncotarget.28651

Madison Rackear, Elias Quijano, Zaira Ianniello, Daniel A. Colón-Ríos, Adam Krysztofiak, Rashed Abdullah, Yanfeng Liu, Faye A. Rogers, Dale L. Ludwig, Rohini Dwivedi, Franziska Bleichert,  and Peter M. Glazer
699-713
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Editorial

Gene regulatory network and signalling pathway rewiring: How blood cancer cells shift their shapes to evade drug treatment

Gene regulatory network and signalling pathway rewiring: How blood cancer cells shift their shapes to evade drug treatment

https://doi.org/10.18632/oncotarget.28662

Constanze Bonifer,  and Peter N. Cockerill
714-716
PDF  |  How to cite  |  Press Release

Case Reports

Complete response to encorafenib plus binimetinib in a BRAF V600E-mutant metastasic malignant glomus tumor

Complete response to encorafenib plus binimetinib in a BRAF V600E-mutant metastasic malignant glomus tumor

https://doi.org/10.18632/oncotarget.28654

Marta Arregui, Antonio Calles, María del Mar Galera, Ana Gutiérrez, Carlos López-Jiménez, Carolina Agra, Adriana Fernández, Natalia Gutiérrez, María de Toro,  and Rosa Álvarez
717-724
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Retraction

Retraction: Integrating mechanisms of response and resistance against the tubulin binding agent Eribulin in preclinical models of osteosarcoma

Retraction: Integrating mechanisms of response and resistance against the tubulin binding agent Eribulin in preclinical models of osteosarcoma

https://doi.org/10.18632/oncotarget.28663

Valerie B. Sampson, Nancy S. Vetter, Wendong Zhang, Pratima U. Patil, Robert W. Mason, Erika George, Richard Gorlick,  and Edward A. Kolb
725-725
Retraction  |  PDF  |  How to cite

Research Papers

Initiation of tumor dormancy by the lymphovascular embolus

Initiation of tumor dormancy by the lymphovascular embolus

https://doi.org/10.18632/oncotarget.28658

Yin Ye, Justin Wang, Michael G. Izban, Billy R. Ballard,  and Sanford H. Barsky
726-740
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Case Reports

A case of adenosquamous pancreatic cancer with a KRAS G12C mutation with an exceptional response to immunotherapy

A case of adenosquamous pancreatic cancer with a KRAS G12C mutation with an exceptional response to immunotherapy

https://doi.org/10.18632/oncotarget.28659

Murtaza Ahmed, Brent K. Larson, Arsen Osipov, Nilofer Azad,  and Andrew Hendifar
741-747
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Corrections

Correction: The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2- dependent ITCH/AIP4 activation

Correction: The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2- dependent ITCH/AIP4 activation

https://doi.org/10.18632/oncotarget.28664

Christophe Le Clorennec, Yassamine Lazrek, Olivier Dubreuil, Christel Larbouret, Marie-Alix Poul, Philippe Mondon, Gerry Melino, André Pèlegrin,  and Thierry Chardès
748-749
Correction  |  PDF  |  How to cite

Research Papers

Relationship between the expressions of DLL3, ASC1, TTF-1 and Ki-67: First steps of precision medicine at SCLC

Relationship between the expressions of DLL3, ASC1, TTF-1 and Ki-67: First steps of precision medicine at SCLC

https://doi.org/10.18632/oncotarget.28660

Samuel Silva, Juliana C. Sousa, Cleto Nogueira, Raquel Feijo, Francisco Martins Neto, Laura Cardoso Marinho, Guilherme Sousa, Valeria Denninghoff,  and Fabio Tavora
750-763
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release  |  Video Interview

Editorial

Beyond the hype: Navigating bias in AI-driven cancer detection

Beyond the hype: Navigating bias in AI-driven cancer detection

https://doi.org/10.18632/oncotarget.28665

Yashbir Singh, Heenaben Patel, Diana V. Vera-Garcia, Quincy A. Hathaway, Deepa Sarkar,  and Emilio Quaia
764-766
PDF  |  How to cite  |  Press Release

Retraction

Retraction: MicroRNA-20a-5p promotes colorectal cancer invasion and metastasis by downregulating Smad4

Retraction: MicroRNA-20a-5p promotes colorectal cancer invasion and metastasis by downregulating Smad4

https://doi.org/10.18632/oncotarget.28669

Dantong Cheng, Senlin Zhao, Huamei Tang, Dongyuan Zhang, Hongcheng Sun, Fudong Yu, Weiliang Jiang, Ben Yue, Jingtao Wang, Meng Zhang, Yang Yu, Xisheng Liu, Xiaofeng Sun, Zongguang Zhou, Xuebin Qin, Xin Zhang, Dongwang Yan, Yugang Wen,  and Zhihai Peng
767-767
Retraction  |  PDF  |  How to cite

Reviews

Understanding the interplay between extracellular matrix topology and tumor-immune interactions: Challenges and opportunities

Understanding the interplay between extracellular matrix topology and tumor-immune interactions: Challenges and opportunities

https://doi.org/10.18632/oncotarget.28666

Yijia Fan, Alvis Chiu, Feng Zhao,  and Jason T. George
768-781
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

Mitigating bias in radiology: The promise of topological data analysis and simplicial complexes

Mitigating bias in radiology: The promise of topological data analysis and simplicial complexes

https://doi.org/10.18632/oncotarget.28668

Yashbir Singh, Colleen Farrelly, Quincy A. Hathaway,  and Gunnar Carlsson
782-783
PDF  |  How to cite  |  Press Release

Editorial

Persistence barcodes: A novel approach to reducing bias in radiological analysis

Persistence barcodes: A novel approach to reducing bias in radiological analysis

https://doi.org/10.18632/oncotarget.28667

Yashbir Singh, Colleen Farrelly, Quincy A. Hathaway,  and Gunnar Carlsson
784-786
PDF  |  How to cite  |  Press Release

Editorial

Visualizing radiological data bias through persistence images

Visualizing radiological data bias through persistence images

https://doi.org/10.18632/oncotarget.28670

Yashbir Singh, Colleen Farrelly, Quincy A. Hathaway,  and Gunnar Carlsson
787-789
PDF  |  How to cite  |  Press Release

Editorial

Persistence landscapes: Charting a path to unbiased radiological interpretation

Persistence landscapes: Charting a path to unbiased radiological interpretation

https://doi.org/10.18632/oncotarget.28671

Yashbir Singh, Colleen Farrelly, Quincy A. Hathaway,  and Gunnar Carlsson
790-792
PDF  |  How to cite  |  Press Release

Reviews

Mesenchymal stem cells - the secret agents of cancer immunotherapy: Promises, challenges, and surprising twists

Mesenchymal stem cells - the secret agents of cancer immunotherapy: Promises, challenges, and surprising twists

https://doi.org/10.18632/oncotarget.28672

Theia Minev, Shani Balbuena, Jaya Mini Gill, Francesco M. Marincola, Santosh Kesari,  and Feng Lin
793-805
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Retraction

Retraction: Hyperglycemia via activation of thromboxane A2 receptor impairs the integrity and function of blood-brain barrier in microvascular endothelial cells

Retraction: Hyperglycemia via activation of thromboxane A2 receptor impairs the integrity and function of blood-brain barrier in microvascular endothelial cells

https://doi.org/10.18632/oncotarget.28675

Zhihong Zhao, Jue Hu, Xiaoping Gao, Hui Liang, Haiya Yu, Suosi Liu,  and Zhan Liu
806-806
Retraction  |  PDF  |  How to cite

Editorial

B7-H4: A potential therapeutic target in adenoid cystic carcinoma

B7-H4: A potential therapeutic target in adenoid cystic carcinoma

https://doi.org/10.18632/oncotarget.28661

Luana Guimaraes de Sousa,  and Renata Ferrarotto
807-808
PDF  |  How to cite  |  Press Release

Research Papers

Computed tomography-based radiomics and body composition model for predicting hepatic decompensation

Computed tomography-based radiomics and body composition model for predicting hepatic decompensation

https://doi.org/10.18632/oncotarget.28673

Yashbir Singh, John E. Eaton, Sudhakar K. Venkatesh,  and Bradley J. Erickson
809-813
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Retraction

Retraction: MicroRNA-34a regulates liver regeneration and the development of liver cancer in rats by targeting Notch signaling pathway

Retraction: MicroRNA-34a regulates liver regeneration and the development of liver cancer in rats by targeting Notch signaling pathway

https://doi.org/10.18632/oncotarget.28676

Xiao-Ping Wang, Jian Zhou, Ming Han, Chuan-Bao Chen, Yi-Tao Zheng, Xiao-Shun He,  and Xiao-Peng Yuan
814-814
Retraction  |  PDF  |  How to cite

News

Advancements in cell-penetrating monoclonal antibody treatment

Advancements in cell-penetrating monoclonal antibody treatment

https://doi.org/10.18632/oncotarget.28674

Sai Pallavi Pradeep,  and Raman Bahal
815-816
PDF  |  How to cite


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