Priority Research Papers

Inherited variants affecting RNA editing may contribute to ovarian cancer susceptibility: results from a largescale collaboration	Inherited variants affecting RNA editing may contribute to ovarian cancer susceptibility: results from a largescale collaboration
https://doi.org/10.18632/oncotarget.10546 Jennifer B. Permuth, Brett Reid, Madalene Earp, Y. Ann Chen, Alvaro NA. Monteiro, Zhihua Chen, AOCS Study Group, Georgia Chenevix-Trench, Peter A. Fasching, Matthias W. Beckmann, Diether Lambrechts, Adriaan Vanderstichele, Els Van Niewenhuyse, Ignace Vergote, Mary Anne Rossing, Jennifer Anne Doherty, Jenny Chang-Claude, Kirsten Moysich, Kunle Odunsi, Marc T. Goodman, Yurii B. Shvetsov, Lynne R. Wilkens, Pamela J. Thompson, Thilo Dörk, Natalia Bogdanova, Ralf Butzow, Heli Nevanlinna, Liisa Pelttari, Arto Leminen, Francesmary Modugno, Robert P. Edwards, Roberta B. Ness, Joseph Kelley, Florian Heitz, Beth Karlan, Jenny Lester, Susanne K. Kjaer, Allan Jensen, Graham Giles, Michelle Hildebrandt, Dong Liang, Karen H. Lu, Xifeng Wu, Douglas A. Levine, Maria Bisogna, Andrew Berchuck, Daniel W. Cramer, Kathryn L. Terry, Shelley S. Tworoger, Elizabeth M. Poole, Elisa V. Bandera, Brooke Fridley, Julie Cunningham, Stacey J. Winham, Sara H. Olson, Irene Orlow, Line Bjorge, Lambertus A. Kiemeney, Leon Massuger, Tanja Pejovic, Melissa Moffitt, Nhu Le, Linda S. Cook, Angela Brooks-Wilson, Linda E. Kelemen, Jacek Gronwald, Jan Lubinski, Nicolas Wentzensen, Louise A. Brinton, Jolanta Lissowska, Hanna Yang, Estrid Hogdall, Claus Hogdall, Lene Lundvall, Paul DP Pharoah, Honglin Song, Ian Campbell, Diana Eccles, Iain McNeish, Alice Whittemore, Valerie McGuire, Weiva Sieh, Joseph Rothstein, Catherine M. Phelan, Harvey Risch, Steven Narod, John McLaughlin, Hoda Anton-Culver, Argyrios Ziogas, Usha Menon, Simon Gayther, Susan J. Ramus, Aleksandra Gentry-Maharaj, Celeste Leigh Pearce, Anna H. Wu, Jolanta Kupryjanczyk, Agnieszka Dansonka-Mieszkowska, Joellen M. Schildkraut, Jin Q. Cheng, Ellen L. Goode, and Thomas A. Sellers
72381-72394

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Multifocal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer	Multifocal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer
https://doi.org/10.18632/oncotarget.11718 Amanda R. Oran, Clare M. Adams, Xiao-yong Zhang, Victoria J. Gennaro, Harla K. Pfeiffer, Hestia S. Mellert, Hans E. Seidel, Kirsten Mascioli, Jordan Kaplan, Mahmoud R. Gaballa, Chen Shen, Isidore Rigoutsos, Michael P. King, Justin L. Cotney, Jamie J. Arnold, Suresh D. Sharma, Ubaldo E. Martinez-Outschoorn, Christopher R. Vakoc, Lewis A. Chodosh, James E. Thompson, James E. Bradner, Craig E. Cameron, Gerald S. Shadel, Christine M. Eischen, and Steven B. McMahon
72395-72414

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The mitochondrial translation machinery as a therapeutic target in Mycdriven lymphomas	The mitochondrial translation machinery as a therapeutic target in Mycdriven lymphomas
https://doi.org/10.18632/oncotarget.11719 Aleco D’Andrea, Ilaria Gritti, Paola Nicoli, Marco Giorgio, Mirko Doni, Annalisa Conti, Valerio Bianchi, Lucia Casoli, Arianna Sabò, Alexandre Mironov, Galina V. Beznoussenko, and Bruno Amati
72415-72430

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Research Papers: Gerotarget (Focus on Aging)

PROX1 is a novel pathwayspecific prognostic biomarker for highgrade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status	PROX1 is a novel pathwayspecific prognostic biomarker for highgrade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status
https://doi.org/10.18632/oncotarget.11957 Kenney R. Roodakker, Tamador Elsir, Per-Henrik D. Edqvist, Daniel Hägerstrand, Joseph Carlson, Malgorzata Lysiak, Roger Henriksson, Fredrik Pontén, Johan Rosell, Peter Söderkvist, Roger Stupp, Elena Tchougounova, Monica Nistér, Annika Malmström, and Anja Smits
72431-72442

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A small molecule inhibitor of PAI1 protects against doxorubicininduced cellular senescence	A small molecule inhibitor of PAI1 protects against doxorubicininduced cellular senescence
https://doi.org/10.18632/oncotarget.12494 Asish K. Ghosh, Rahul Rai, Kitae E. Park, Mesut Eren, Toshio Miyata, Lisa D. Wilsbacher, and Douglas E. Vaughan
72443-72457

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Baicalein protects against oxLDLcaused oxidative stress and inflammation by modulation of AMPK alpha	Baicalein protects against oxLDLcaused oxidative stress and inflammation by modulation of AMPK alpha
https://doi.org/10.18632/oncotarget.12788 Kun-Ling Tsai, Ching-Hsia Hung, Shih-Hung Chan, Jhih-Yuan Shih, Yung-Hsin Cheng, Yi-Ju Tsai, Huei-Chen Lin, and Pei-Ming Chu
72458-72468

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Research Papers: Pathology

Gene expression analysis reveals the dysregulation of immune and metabolic pathways in Alzheimer’s disease	Gene expression analysis reveals the dysregulation of immune and metabolic pathways in Alzheimer’s disease
https://doi.org/10.18632/oncotarget.12505 Juan Chen, Chuncheng Xie, Yanhong Zhao, Zhiyan Li, Panpan Xu, and Lifen Yao
72469-72474

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Tolllike 4 receptor /NFκB inflammatory/miR146a pathway contributes to the ARTcorrelated preterm birth outcome	Tolllike 4 receptor /NFκB inflammatory/miR146a pathway contributes to the ARTcorrelated preterm birth outcome
https://doi.org/10.18632/oncotarget.11987 Xinqi Zhong, Yi-Zhou Jiang, Peiwen Liu, Wenzhi He, Zhongtang Xiong, Weijie Chang, Jiandong Zhu, and Qiliang Cui
72475-72485

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RNA binding protein tristetraprolin in a murine model of recurrent pregnancy loss	RNA binding protein tristetraprolin in a murine model of recurrent pregnancy loss
https://doi.org/10.18632/oncotarget.12539 Kasra Khalaj, Rayana Leal Luna, Maria Eduarda Rocha de França, Wilma Helena de Oliveira, Christina Alves Peixoto, and Chandrakant Tayade
72486-72502

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Wogonin prevents TLR4NFκBmedicated neuroinflammation and improves retinal ganglion cells survival in retina after optic nerve crush	Wogonin prevents TLR4NFκBmedicated neuroinflammation and improves retinal ganglion cells survival in retina after optic nerve crush
https://doi.org/10.18632/oncotarget.12700 Yue Xu, Boyu Yang, Yaguang Hu, Lin Lu, Xi Lu, Jiawei Wang, Fan Xu, Shanshan Yu, Jingjing Huang, and Xiaoling Liang
72503-72517

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Research Papers: Immunology

Proteomic analysis uncovers common effects of IFNγ and IL27 on the HLA class I antigen presentation machinery in human cancer cells	Proteomic analysis uncovers common effects of IFNγ and IL27 on the HLA class I antigen presentation machinery in human cancer cells
https://doi.org/10.18632/oncotarget.12235 Andrea Petretto, Grazia Carbotti, Elvira Inglese, Chiara Lavarello, Maria Pia Pistillo, Valentina Rigo, Michela Croce, Luca Longo, Stefania Martini, Paola Vacca, Silvano Ferrini, and Marina Fabbi
72518-72536

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Umbilical cordderived mesenchymal stem cells reversed the suppressive deficiency of T regulatory cells from peripheral blood of patients with multiple sclerosis in a coculture – a preliminary study	Umbilical cordderived mesenchymal stem cells reversed the suppressive deficiency of T regulatory cells from peripheral blood of patients with multiple sclerosis in a coculture – a preliminary study
https://doi.org/10.18632/oncotarget.12345 Hongna Yang, Jinhua Sun, Feng Wang, Yan Li, Jianzhong Bi, and Tingyu Qu
72537-72545

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A long noncoding RNA positively regulates CD56 in human natural killer cells	A long noncoding RNA positively regulates CD56 in human natural killer cells
https://doi.org/10.18632/oncotarget.12466 Ruya Zhang, Fang Ni, Binqing Fu, Yang Wu, Rui Sun, Zhigang Tian, and Haiming Wei
72546-72558

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Generation of infectious RNA complexes in orbiviruses: RNARNA interactions of genomic segments	Generation of infectious RNA complexes in orbiviruses: RNARNA interactions of genomic segments
https://doi.org/10.18632/oncotarget.12496 Teodoro Fajardo Jr., Kinda AlShaikhahmed, and Polly Roy
72559-72570

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Research Papers: Chromosome

ZSCAN5B and primatespecific paralogs bind RNA polymerase III genes and extraTFIIIC ETC sites to modulate mitotic progression	ZSCAN5B and primatespecific paralogs bind RNA polymerase III genes and extraTFIIIC ETC sites to modulate mitotic progression
https://doi.org/10.18632/oncotarget.12508 Younguk Sun, Huimin Zhang, Majid Kazemian, Joseph M. Troy, Christopher Seward, Xiaochen Lu, and Lisa Stubbs
72571-72592

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Research Papers

Identification of miR30b3p and miR30d5p as direct regulators of androgen receptor signaling in prostate cancer by complementary functional microRNA library screening	Identification of miR30b3p and miR30d5p as direct regulators of androgen receptor signaling in prostate cancer by complementary functional microRNA library screening
https://doi.org/10.18632/oncotarget.12241 Binod Kumar, Salar Khaleghzadegan, Brian Mears, Koji Hatano, Tarana A. Kudrolli, Wasim H. Chowdhury, David B. Yeater, Charles M. Ewing, Jun Luo, William B. Isaacs, Luigi Marchionni, and Shawn E. Lupold
72593-72607

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Janus and PI3kinases mediate glucocorticoid resistance in activated chronic leukemia cells	Janus and PI3kinases mediate glucocorticoid resistance in activated chronic leukemia cells
https://doi.org/10.18632/oncotarget.11618 Sina Oppermann, Avery J. Lam, Stephanie Tung, Yonghong Shi, Lindsay McCaw, Guizhei Wang, Jarkko Ylanko, Brian Leber, David Andrews, and David E. Spaner
72608-72621

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Tumor and circulating biomarkers in patients with secondline hepatocellular carcinoma from the randomized phase II study with tivantinib	Tumor and circulating biomarkers in patients with secondline hepatocellular carcinoma from the randomized phase II study with tivantinib
https://doi.org/10.18632/oncotarget.11621 Lorenza Rimassa, Giovanni Abbadessa, Nicola Personeni, Camillo Porta, Ivan Borbath, Bruno Daniele, Stefania Salvagni, Jean-Luc Van Laethem, Hans Van Vlierberghe, Jörg Trojan, Enrico N. De Toni, Alan Weiss, Steven Miles, Antonio Gasbarrini, Monica Lencioni, Maria E. Lamar, Yunxia Wang, Dale Shuster, Brian E. Schwartz, and Armando Santoro
72622-72633

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Smac mimetic LCL161 supports neuroblastoma chemotherapy in a drug classdependent manner and synergistically interacts with ALK inhibitor TAE684 in cells with ALK mutation F1174L	Smac mimetic LCL161 supports neuroblastoma chemotherapy in a drug classdependent manner and synergistically interacts with ALK inhibitor TAE684 in cells with ALK mutation F1174L
https://doi.org/10.18632/oncotarget.12055 Safiullah Najem, Doerte Langemann, Birgit Appl, Magdalena Trochimiuk, Patrick Hundsdoerfer, Konrad Reinshagen, and Georg Eschenburg
72634-72653

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Biomarker analysis of the MITO2 phase III trial of firstline treatment in ovarian cancer: predictive value of DNAPK and phosphorylated ACC	Biomarker analysis of the MITO2 phase III trial of firstline treatment in ovarian cancer: predictive value of DNAPK and phosphorylated ACC
https://doi.org/10.18632/oncotarget.12056 Francesco Perrone, Gustavo Baldassarre, Stefano Indraccolo, Simona Signoriello, Gennaro Chiappetta, Franca Esposito, Gabriella Ferrandina, Renato Franco, Delia Mezzanzanica, Maura Sonego, Elisabetta Zulato, Gian F. Zannoni, Vincenzo Canzonieri, Giovanni Scambia, Roberto Sorio, Antonella Savarese, Enrico Breda, Paolo Scollo, Antonella Ferro, Stefano Tamberi, Antonio Febbraro, Donato Natale, Massimo Di Maio, Daniela Califano, Giosuè Scognamiglio, Domenica Lorusso, Silvana Canevari, Simona Losito, Ciro Gallo, and Sandro Pignata
72654-72661

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IMP1 an mRNA binding protein that reduces the metastatic potential of breast cancer in a mouse model	IMP1 an mRNA binding protein that reduces the metastatic potential of breast cancer in a mouse model
https://doi.org/10.18632/oncotarget.12083 Chiso U. Nwokafor, Rani S. Sellers, and Robert H. Singer
72662-72671

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Role of Dicer as a prognostic predictor for survival in cancer patients: a systematic review with a metaanalysis	Role of Dicer as a prognostic predictor for survival in cancer patients: a systematic review with a metaanalysis
https://doi.org/10.18632/oncotarget.12183 Wanying Shan, Chaoyang Sun, Bo Zhou, Ensong Guo, Hao Lu, Meng Xia, Kezhen Li, Danhui Weng, Xingguang Lin, Li Meng, Ding Ma, and Gang Chen
72672-72684

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Perturbed hematopoietic stem and progenitor cell hierarchy in myelodysplastic syndromes patients with monosomy 7 as the sole cytogenetic abnormality	Perturbed hematopoietic stem and progenitor cell hierarchy in myelodysplastic syndromes patients with monosomy 7 as the sole cytogenetic abnormality
https://doi.org/10.18632/oncotarget.12234 Marios Dimitriou, Petter S. Woll, Teresa Mortera-Blanco, Mohsen Karimi, David C. Wedge, Helen Doolittle, Iyadh Douagi, Elli Papaemmanuil, Sten Eirik W. Jacobsen, and Eva Hellström-Lindberg
72685-72698

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Interaction of microtubules with the actin cytoskeleton via crosstalk of EB1containing +TIPs and γactin in epithelial cells	Interaction of microtubules with the actin cytoskeleton via crosstalk of EB1containing +TIPs and γactin in epithelial cells
https://doi.org/10.18632/oncotarget.12236 Vera Dugina, Irina Alieva, Natalya Khromova, Igor Kireev, Peter W. Gunning, and Pavel Kopnin
72699-72715

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Regulation of tumor growth by circulating fulllength chromogranin A	Regulation of tumor growth by circulating fulllength chromogranin A
https://doi.org/10.18632/oncotarget.12237 Flavio Curnis, Alice Dallatomasina, Mimma Bianco, Anna Gasparri, Angelina Sacchi, Barbara Colombo, Martina Fiocchi, Laura Perani, Massimo Venturini, Carlo Tacchetti, Suvajit Sen, Ricardo Borges, Eleonora Dondossola, Antonio Esposito, Sushil K. Mahata, and Angelo Corti
72716-72732

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Clonal and microclonal mutational heterogeneity in high hyperdiploid acute lymphoblastic leukemia	Clonal and microclonal mutational heterogeneity in high hyperdiploid acute lymphoblastic leukemia
https://doi.org/10.18632/oncotarget.12238 Adam J. de Smith, Juhi Ojha, Stephen S. Francis, Erica Sanders, Alyson A. Endicott, Helen M. Hansen, Ivan Smirnov, Amanda M. Termuhlen, Kyle M. Walsh, Catherine Metayer, and Joseph L. Wiemels
72733-72745

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MicroRNA26b attenuates monocrotalineinduced pulmonary vascular remodeling via targeting connective tissue growth factor CTGF and cyclin D1 CCND1	MicroRNA26b attenuates monocrotalineinduced pulmonary vascular remodeling via targeting connective tissue growth factor CTGF and cyclin D1 CCND1
https://doi.org/10.18632/oncotarget.10125 Ran Wang, Xing Ding, Sijing Zhou, Min Li, Li Sun, Xuan Xu, and Guanghe Fei
72746-72757

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Computational identification of microRNAs associated to both epithelial to mesenchymal transition and NGAL/MMP9 pathways in bladder cancer	Computational identification of microRNAs associated to both epithelial to mesenchymal transition and NGAL/MMP9 pathways in bladder cancer
https://doi.org/10.18632/oncotarget.11805 Luca Falzone, Saverio Candido, Rossella Salemi, Maria S. Basile, Aurora Scalisi, James A. McCubrey, Francesco Torino, Salvatore S. Signorelli, Maurizio Montella, and Massimo Libra
72758-72766

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Aberrant expression of KPNA2 is associated with a poor prognosis and contributes to OCT4 nuclear transportation in bladder cancer	Aberrant expression of KPNA2 is associated with a poor prognosis and contributes to OCT4 nuclear transportation in bladder cancer
https://doi.org/10.18632/oncotarget.11889 Jingcheng Zhou, Daoquan Dong, Ran Cheng, Yan Wang, Shuqi Jiang, Yuhong Zhu, Longlong Fan, Xiangming Mao, Yaoting Gui, Zesong Li, Xianxin Li, and Bentao Shi
72767-72776

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cAbl inhibits breast cancer tumorigenesis through reactivation of p53mediated p21 expression	cAbl inhibits breast cancer tumorigenesis through reactivation of p53mediated p21 expression
https://doi.org/10.18632/oncotarget.11909 Chevaun D. Morrison, Tressa M. Allington, Cheryl L. Thompson, Hannah L. Gilmore, Jenny C. Chang, Ruth A. Keri, and William P. Schiemann
72777-72794

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DRG1 is a potential oncogene in lung adenocarcinoma and promotes tumor progression via spindle checkpoint signaling regulation	DRG1 is a potential oncogene in lung adenocarcinoma and promotes tumor progression via spindle checkpoint signaling regulation
https://doi.org/10.18632/oncotarget.11973 Li Lu, Yanrong Lv, Ji Dong, Shaohua Hu, and Ruiyun Peng
72795-72806

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SASH1 mediates sensitivity of breast cancer cells to chloropyramine and is associated with prognosis in breast cancer	SASH1 mediates sensitivity of breast cancer cells to chloropyramine and is associated with prognosis in breast cancer
https://doi.org/10.18632/oncotarget.12020 Joshua T. Burgess, Emma Bolderson, Jodi M. Saunus, Shu-Dong Zhang, Lynne E. Reid, Anne Marie McNicol, Sunil R. Lakhani, Katharine Cuff, Kerry Richard, Derek J. Richard, and Kenneth J. O’Byrne
72807-72818

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Prognostic role and correlation of CA9 CD31 CD68 and CD20 with the desmoplastic stroma in pancreatic ductal adenocarcinoma	Prognostic role and correlation of CA9 CD31 CD68 and CD20 with the desmoplastic stroma in pancreatic ductal adenocarcinoma
https://doi.org/10.18632/oncotarget.12022 Angela Diana, Lai Mun Wang, Zenobia D’Costa, Abul Azad, Michael A. Silva, Zahir Soonawalla, Paul Allen, Stanley Liu, W. Gillies McKenna, Ruth J. Muschel, and Emmanouil Fokas
72819-72832

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Long noncoding RNA CRNDE promotes gallbladder carcinoma carcinogenesis and as a scaffold of DMBT1 and CIAP1 complexes to activating PI3KAKT pathway	Long noncoding RNA CRNDE promotes gallbladder carcinoma carcinogenesis and as a scaffold of DMBT1 and CIAP1 complexes to activating PI3KAKT pathway
https://doi.org/10.18632/oncotarget.12023 Sheng Shen, Han Liu, Yueqi Wang, Jiwen Wang, Xiaolin Ni, Zhilong Ai, Hongtao Pan, Houbao Liu, and Yebo Shao
72833-72844

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Aberrant expression of JNKassociated leucinezipper protein JLP promotes accelerated growth of ovarian cancer	Aberrant expression of JNKassociated leucinezipper protein JLP promotes accelerated growth of ovarian cancer
https://doi.org/10.18632/oncotarget.12069 Ji Hee Ha, Mingda Yan, Rohini Gomathinayagam, Muralidharan Jayaraman, Sanam Husain, Jinsong Liu, Priyabrata Mukherjee, E. Premkumar Reddy, Yong Sang Song, and Danny N. Dhanasekaran
72845-72859

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Comprehensive adipocytic and neurogenic tissue microarray analysis of NYESO1 expression a promising immunotherapy target in malignant peripheral nerve sheath tumor and liposarcoma	Comprehensive adipocytic and neurogenic tissue microarray analysis of NYESO1 expression a promising immunotherapy target in malignant peripheral nerve sheath tumor and liposarcoma
https://doi.org/10.18632/oncotarget.12096 Elizabeth Shurell, Maria E. Vergara-Lluri, Yunfeng Li, Joseph G. Crompton, Arun Singh, Nicholas Bernthal, Hong Wu, Fritz C. Eilber, and Sarah M. Dry
72860-72867

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Antitumor activity of a novel antivascular endothelial growth factor receptor1 monoclonal antibody that does not interfere with ligand binding	Antitumor activity of a novel antivascular endothelial growth factor receptor1 monoclonal antibody that does not interfere with ligand binding
https://doi.org/10.18632/oncotarget.12108 Grazia Graziani, Federica Ruffini, Lucio Tentori, Manuel Scimeca, Annalisa S. Dorio, Maria Grazia Atzori, Cristina M. Failla, Veronica Morea, Elena Bonanno, Stefania D’Atri, and Pedro M. Lacal
72868-72885

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Synergistic activity of ALK and mTOR inhibitors for the treatment of NPMALK positive lymphoma	Synergistic activity of ALK and mTOR inhibitors for the treatment of NPMALK positive lymphoma
https://doi.org/10.18632/oncotarget.12128 Sara Redaelli, Monica Ceccon, Laura Antolini, Roberta Rigolio, Alessandra Pirola, Marco Peronaci, Carlo Gambacorti-Passerini, and Luca Mologni
72886-72897

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Prognostic role of the lymph node ratio in node positive colorectal cancer: a metaanalysis	Prognostic role of the lymph node ratio in node positive colorectal cancer: a metaanalysis
https://doi.org/10.18632/oncotarget.12131 Ming-Ran Zhang, Tian-Hang Xie, Jun-Lin Chi, Yuan Li, Lie Yang, Yong-Yang Yu, Xiao-Feng Sun, and Zong-Guang Zhou
72898-72907

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Genomic characterization of liver metastases from colorectal cancer patients	Genomic characterization of liver metastases from colorectal cancer patients
https://doi.org/10.18632/oncotarget.12140 José María Sayagués, Luís Antonio Corchete, María Laura Gutiérrez, Maria Eugenia Sarasquete, María del Mar Abad, Oscar Bengoechea, Encarna Fermiñán, María Fernanda Anduaga, Sofia del Carmen, Manuel Iglesias, Carmen Esteban, María Angoso, Jose Antonio Alcazar, Jacinto García, Alberto Orfao, and Luís Muñoz-Bellvis
72908-72922

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Grp94 in complexes with IgG is a soluble diagnostic marker of gastrointestinal tumors and displays immunestimulating activity on peripheral blood immune cells	Grp94 in complexes with IgG is a soluble diagnostic marker of gastrointestinal tumors and displays immunestimulating activity on peripheral blood immune cells
https://doi.org/10.18632/oncotarget.12141 Elisa Tramentozzi, Erlis Ruli, Imerio Angriman, Romeo Bardini, Michela Campora, Vincenza Guzzardo, Rita Zamarchi, Elisabetta Rossi, Massimo Rugge, and Paola Finotti
72923-72940

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Decreased TRPM7 inhibits activities and induces apoptosis of bladder cancer cells via ERK1/2 pathway	Decreased TRPM7 inhibits activities and induces apoptosis of bladder cancer cells via ERK1/2 pathway
https://doi.org/10.18632/oncotarget.12146 Rui Cao, Zhe Meng, Tongzu Liu, Gang Wang, Guofeng Qian, Tingting Cao, Xinyuan Guan, Hancai Dan, Yu Xiao, and Xinghuan Wang
72941-72960

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PD1 mediates functional exhaustion of activated NK cells in patients with Kaposi sarcoma	PD1 mediates functional exhaustion of activated NK cells in patients with Kaposi sarcoma
https://doi.org/10.18632/oncotarget.12150 Asma Beldi-Ferchiou, Marion Lambert, Stéphanie Dogniaux, Frédéric Vély, Eric Vivier, Daniel Olive, Stéphanie Dupuy, Frank Levasseur, David Zucman, Céleste Lebbé, Damien Sène, Claire Hivroz, and Sophie Caillat-Zucman
72961-72977

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Multicycle chemotherapy with the glycolipidlike polymeric micelles evade cancer stem cell enrichment in breast cancer therapy	Multicycle chemotherapy with the glycolipidlike polymeric micelles evade cancer stem cell enrichment in breast cancer therapy
https://doi.org/10.18632/oncotarget.12159 Tingting Meng, Jingwen Liu, Lijuan Wen, Ming Yuan, Bolin Cheng, Yingwen Hu, Yun Zhu, Xuan Liu, Hong Yuan, and Fuqiang Hu
72978-72989

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Geridonin and paclitaxel act synergistically to inhibit the proliferation of gastric cancer cells through ROSmediated regulation of the PTEN/PI3K/Akt pathway	Geridonin and paclitaxel act synergistically to inhibit the proliferation of gastric cancer cells through ROSmediated regulation of the PTEN/PI3K/Akt pathway
https://doi.org/10.18632/oncotarget.12166 Sai-Qi Wang, Cong Wang, Li-Ming Chang, Kai-Rui Zhou, Jun-Wei Wang, Yu Ke, Dong-Xiao Yang, Hong-Ge Shi, Ran Wang, Xiao-Li Shi, Li-Ying Ma, and Hong-Min Liu
72990-73002

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Elevated level of Interleukin35 in colorectal cancer induces conversion of T cells into iTr35 by activating STAT1/STAT3	Elevated level of Interleukin35 in colorectal cancer induces conversion of T cells into iTr35 by activating STAT1/STAT3
https://doi.org/10.18632/oncotarget.12193 Yanhui Ma, Lei Chen, Guohua Xie, Yunlan Zhou, Chaoyan Yue, Xiangliang Yuan, Yingxia Zheng, Weiwei Wang, Lin Deng, and Lisong Shen
73003-73015

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Targeting cancer initiating cells by promoting cell differentiation and restoring chemosensitivity via dual inactivation of STAT3 and Src activity using an active component of Antrodia cinnamomea mycelia	Targeting cancer initiating cells by promoting cell differentiation and restoring chemosensitivity via dual inactivation of STAT3 and Src activity using an active component of Antrodia cinnamomea mycelia
https://doi.org/10.18632/oncotarget.12194 Ching-Wen Chang, Yu-Syuan Chen, Chien-Chih Chen, Ik-On Chan, Chin-Chu Chen, Sen-Je Sheu, Ting-wei Lin, Shiu-Huey Chou, Chung-Ji Liu, Te-Chang Lee, and Jeng-Fan Lo
73016-73031

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Overcoming adaptive resistance in mucoepidermoid carcinoma through inhibition of the IKKβ/IκBα/NFκB axis	Overcoming adaptive resistance in mucoepidermoid carcinoma through inhibition of the IKKβ/IκBα/NFκB axis
https://doi.org/10.18632/oncotarget.12195 Vivian P. Wagner, Marco A.T. Martins, Manoela D. Martins, Kristy A. Warner, Liana P. Webber, Cristiane H. Squarize, Jacques E. Nör, and Rogerio M. Castilho
73032-73044

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Tumour suppressor gene CDKNA2 status on chromosome 9p in resected renal tissue improves prognosis of localised kidney cancer	Tumour suppressor gene CDKNA2 status on chromosome 9p in resected renal tissue improves prognosis of localised kidney cancer
https://doi.org/10.18632/oncotarget.12196 Ismail El-Mokadem, Thomas Kidd, Norman Pratt, Stewart Fleming, and Ghulam Nabi
73045-73054

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The Cterminal domain of connexin43 modulates cartilage structure via chondrocyte phenotypic changes	The Cterminal domain of connexin43 modulates cartilage structure via chondrocyte phenotypic changes
https://doi.org/10.18632/oncotarget.12197 Raquel Gago-Fuentes, John F. Bechberger, Marta Varela-Eirin, Adrian Varela-Vazquez, Benigno Acea, Eduardo Fonseca, Christian C. Naus, and Maria D. Mayan
73055-73067

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The efficacy and safety of antiPD1/PDL1 antibodies for treatment of advanced or refractory cancers: a metaanalysis	The efficacy and safety of antiPD1/PDL1 antibodies for treatment of advanced or refractory cancers: a metaanalysis
https://doi.org/10.18632/oncotarget.12230 Tengfei Zhang, Jing Xie, Seiji Arai, Liping Wang, Xuezhong Shi, Ni Shi, Fen Ma, Sen Chen, Lan Huang, Li Yang, Wang Ma, Bin Zhang, Weidong Han, Jianchuan Xia, Hu Chen, and Yi Zhang
73068-73079

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Dandelion root extract affects colorectal cancer proliferation and survival through the activation of multiple death signalling pathways	Dandelion root extract affects colorectal cancer proliferation and survival through the activation of multiple death signalling pathways
https://doi.org/10.18632/oncotarget.11485 Pamela Ovadje, Saleem Ammar, Jose-Antonio Guerrero, John Thor Arnason, and Siyaram Pandey
73080-73100

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The role of SH3GL3 in myeloma cell migration/invasion stemness and chemoresistance	The role of SH3GL3 in myeloma cell migration/invasion stemness and chemoresistance
https://doi.org/10.18632/oncotarget.12231 Ruoying Chen, Hong Zhao, Dan Wu, Chen Zhao, Weiling Zhao, and Xiaobo Zhou
73101-73113

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A novel codrug of aspirin and ursolic acid interrupts adhesion invasion and migration of cancer cells to vascular endothelium via regulating EMT and EGFRmediated signaling pathways: multiple targets for cancer metastasis prevention and treatment	A novel codrug of aspirin and ursolic acid interrupts adhesion invasion and migration of cancer cells to vascular endothelium via regulating EMT and EGFRmediated signaling pathways: multiple targets for cancer metastasis prevention and treatment
https://doi.org/10.18632/oncotarget.12232 Qiao Tang, Yajun Liu, Tao Li, Xiang Yang, Guirong Zheng, Hongning Chen, Lee Jia, and Jingwei Shao
73114-73129

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Intraglomerular crosstalk elaborately regulates podocyte injury and repair in diabetic patients: insights from a 3D multiscale modeling study	Intraglomerular crosstalk elaborately regulates podocyte injury and repair in diabetic patients: insights from a 3D multiscale modeling study
https://doi.org/10.18632/oncotarget.12233 Hua Tan, Hualin Yi, Weiling Zhao, Jian-Xing Ma, Yuanyuan Zhang, and Xiaobo Zhou
73130-73146

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Adipocytes cause leukemia cell resistance to daunorubicin via oxidative stress response	Adipocytes cause leukemia cell resistance to daunorubicin via oxidative stress response
https://doi.org/10.18632/oncotarget.12246 Xia Sheng, Jonathan Tucci, Jean-Hugues Parmentier, Lingyun Ji, James W. Behan, Nora Heisterkamp, and Steven D. Mittelman
73147-73159

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Cyr61positive cancer stemlike cells enhances distal metastases of pancreatic cancer	Cyr61positive cancer stemlike cells enhances distal metastases of pancreatic cancer
https://doi.org/10.18632/oncotarget.12248 Weidong Shi, Chenyue Zhang, Zhen Chen, Hao Chen, Luming Liu, and Zhiqiang Meng
73160-73170

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Expression of the TPα and TPβ isoforms of the thromboxane prostanoid receptor TP in prostate cancer: clinical significance and diagnostic potential	Expression of the TPα and TPβ isoforms of the thromboxane prostanoid receptor TP in prostate cancer: clinical significance and diagnostic potential
https://doi.org/10.18632/oncotarget.12256 Eamon P. Mulvaney, Christine Shilling, Sarah B. Eivers, Antoinette S. Perry, Anders Bjartell, Elaine W. Kay, R. William Watson, and B. Therese Kinsella
73171-73187

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR128 reverses the gefitinib resistance of the lung cancer stem cells by inhibiting the cmet/PI3K/AKT pathway	MiR128 reverses the gefitinib resistance of the lung cancer stem cells by inhibiting the cmet/PI3K/AKT pathway
https://doi.org/10.18632/oncotarget.12283 Jingjin Jiang, Xiaoning Feng, Wenjing Zhou, Yue Wu, and Yunmei Yang
73188-73199

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Casespecific potentiation of glioblastoma drugs by pterostilbene	Casespecific potentiation of glioblastoma drugs by pterostilbene
https://doi.org/10.18632/oncotarget.12298 Linnéa Schmidt, Sathishkumar Baskaran, Patrik Johansson, Narendra Padhan, Damian Matuszewski, Lydia C Green, Ludmila Elfineh, Shimei Wee, Maria Häggblad, Ulf Martens, Bengt Westermark, Karin Forsberg-Nilsson, Lene Uhrbom, Lena Claesson-Welsh, Michael Andäng, Ida-Maria Sintorn, Bo Lundgren, Ingrid Lönnstedt, Cecilia Krona, and Sven Nelander
73200-73215

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ADH1B and CDH1 polymorphisms predict prognosis in male patients with nonmetastatic laryngeal cancer	ADH1B and CDH1 polymorphisms predict prognosis in male patients with nonmetastatic laryngeal cancer
https://doi.org/10.18632/oncotarget.12301 Daxu Li, Ruizhi Zhang, Tianbo Jin, Na He, Le Ren, Zhe Zhang, Qingna Zhang, Ran Xu, Hong Tao, Guang Zeng, and Jing Gao
73216-73228

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Enhancement of endothelial permeability by free fatty acid through lysosomal cathepsin Bmediated Nlrp3 inflammasome activation	Enhancement of endothelial permeability by free fatty acid through lysosomal cathepsin Bmediated Nlrp3 inflammasome activation
https://doi.org/10.18632/oncotarget.12302 Lei Wang, Yang Chen, Xiang Li, Youzhi Zhang, Erich Gulbins, and Yang Zhang
73229-73241

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Catalytically defective receptor protein tyrosine kinase PTK7 enhances invasive phenotype by inducing MMP9 through activation of AP1 and NFκB in esophageal squamous cell carcinoma cells	Catalytically defective receptor protein tyrosine kinase PTK7 enhances invasive phenotype by inducing MMP9 through activation of AP1 and NFκB in esophageal squamous cell carcinoma cells
https://doi.org/10.18632/oncotarget.12303 Won-Sik Shin, Yuri Hong, Hae Won Lee, and Seung-Taek Lee
73242-73256

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

An artificial lncRNA targeting multiple miRNAs overcomes sorafenib resistance in hepatocellular carcinoma cells	An artificial lncRNA targeting multiple miRNAs overcomes sorafenib resistance in hepatocellular carcinoma cells
https://doi.org/10.18632/oncotarget.12304 Shuyao Tang, Gang Tan, Xian Jiang, Peng Han, Bo Zhai, Xuesong Dong, Haiquan Qiao, Hongchi Jiang, and Xueying Sun
73257-73269

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Low carbohydrate diet prevents Mcl1mediated resistance to BH3mimetics	Low carbohydrate diet prevents Mcl1mediated resistance to BH3mimetics
https://doi.org/10.18632/oncotarget.12309 Camila Rubio-Patiño, Jozef P. Bossowski, Elodie Villa, Laura Mondragón, Barbara Zunino, Emma Proïcs, Johanna Chiche, Frédéric Bost, Els Verhoeyen, and Jean-Ehrland Ricci
73270-73279

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Thermosensitive composite hydrogels based on poloxamer 407 and alginate and their therapeutic effect in embolization in rabbit VX2 liver tumors	Thermosensitive composite hydrogels based on poloxamer 407 and alginate and their therapeutic effect in embolization in rabbit VX2 liver tumors
https://doi.org/10.18632/oncotarget.11789 Lili Huang, Ming Shen, Rongxin Li, Xiangyu Zhang, Ying Sun, Pei Gao, Hao Fu, Hongqiang Liu, Yang He, Yuqing Du, Jun Cao, and Yourong Duan
73280-73291

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Coapplication of canavanine and irradiation uncouples anticancer potential of arginine deprivation from citrulline availability	Coapplication of canavanine and irradiation uncouples anticancer potential of arginine deprivation from citrulline availability
https://doi.org/10.18632/oncotarget.12320 Yuliya Kurlishchuk, Bozhena Vynnytska-Myronovska, Philipp Grosse-Gehling, Yaroslav Bobak, Friederike Manig, Oleg Chen, Sebastian R. Merker, Thomas Henle, Steffen Löck, Daniel E. Stange, Oleh Stasyk, and Leoni A. Kunz-Schughart
73292-73308

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Keratin 18deficiency results in steatohepatitis and liver tumors in old mice: A model of steatohepatitisassociated liver carcinogenesis	Keratin 18deficiency results in steatohepatitis and liver tumors in old mice: A model of steatohepatitisassociated liver carcinogenesis
https://doi.org/10.18632/oncotarget.12325 Kira Bettermann, Anita Kuldeep Mehta, Eva M. Hofer, Christina Wohlrab, Nicole Golob-Schwarzl, Vendula Svendova, Michael G. Schimek, Cornelia Stumptner, Andrea Thüringer, Michael R. Speicher, Carolin Lackner, Kurt Zatloukal, Helmut Denk, and Johannes Haybaeck
73309-73322

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

p53 in the mitochondria as a transacting protein provides errorcorrection activities during the incorporation of noncanonical dUTP into DNA	p53 in the mitochondria as a transacting protein provides errorcorrection activities during the incorporation of noncanonical dUTP into DNA
https://doi.org/10.18632/oncotarget.12331 Elad Bonda, Galia Rahav, Angelina Kaya, and Mary Bakhanashvili
73323-73336

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ERBB2 mutations associated with solid variant of highgrade invasive lobular breast carcinomas	ERBB2 mutations associated with solid variant of highgrade invasive lobular breast carcinomas
https://doi.org/10.18632/oncotarget.11819 Gabrielle Deniziaut, Jean Christophe Tille, François-Clément Bidard, Sophie Vacher, Anne Schnitzler, Walid Chemlali, Laurence Tremoulet, Laetitia Fuhrmann, Paul Cottu, Roman Rouzier, Ivan Bièche, and Anne Vincent-Salomon
73337-73346

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Promoter methylation patterns of ABCB1 ABCC1 and ABCG2 in human cancer cell lines multidrugresistant cell models and tumor tumoradjacent and tumordistant tissues from breast cancer patients	Promoter methylation patterns of ABCB1 ABCC1 and ABCG2 in human cancer cell lines multidrugresistant cell models and tumor tumoradjacent and tumordistant tissues from breast cancer patients
https://doi.org/10.18632/oncotarget.12332 Melanie Spitzwieser, Christine Pirker, Bettina Koblmüller, Georg Pfeiler, Stefan Hacker, Walter Berger, Petra Heffeter, and Margit Cichna-Markl
73347-73369

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

CARP1 functional mimetics are novel inhibitors of drugresistant triple negative breast cancers	CARP1 functional mimetics are novel inhibitors of drugresistant triple negative breast cancers
https://doi.org/10.18632/oncotarget.12333 Vino T. Cheriyan, Magesh Muthu, Ketan Patel, Sreeja Sekhar, Walajapet Rajeswaran, Scott D. Larsen, Lisa Polin, Edi Levi, Mandip Singh, and Arun K. Rishi
73370-73388

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

LKB1 is a DNA damage response protein that regulates cellular sensitivity to PARP inhibitors	LKB1 is a DNA damage response protein that regulates cellular sensitivity to PARP inhibitors
https://doi.org/10.18632/oncotarget.12334 Yi-Shu Wang, Jianfeng Chen, Fengmei Cui, Huibo Wang, Shuai Wang, Wei Hang, Qinghua Zeng, Cheng-Shi Quan, Ying-Xian Zhai, Jian-Wei Wang, Xiang-Feng Shen, Yong-Ping Jian, Rui-Xun Zhao, Kaitlin D. Werle, Rutao Cui, Jiyong Liang, Yu-Lin Li, and Zhi-Xiang Xu
73389-73401

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Asporin enhances colorectal cancer metastasis through activating the EGFR/Src/cortactin signaling pathway	Asporin enhances colorectal cancer metastasis through activating the EGFR/Src/cortactin signaling pathway
https://doi.org/10.18632/oncotarget.12336 Huo Wu, Xiaoqian Jing, Xi Cheng, Yonggang He, Lei Hu, Haoxuan Wu, Feng Ye, and Ren Zhao
73402-73413

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Reciprocal regulation of the cholinic phenotype and epithelialmesenchymal transition in glioblastoma cells	Reciprocal regulation of the cholinic phenotype and epithelialmesenchymal transition in glioblastoma cells
https://doi.org/10.18632/oncotarget.12337 Katharina Koch, Rudolf Hartmann, Friederike Schröter, Abigail Kora Suwala, Donata Maciaczyk, Andrea Caroline Krüger, Dieter Willbold, Ulf Dietrich Kahlert, and Jaroslaw Maciaczyk
73414-73431

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Isoliquiritigenin induces apoptosis and autophagy and inhibits endometrial cancer growth in mice	Isoliquiritigenin induces apoptosis and autophagy and inhibits endometrial cancer growth in mice
https://doi.org/10.18632/oncotarget.12369 Chi-Hao Wu, Hsin-Yuan Chen, Chia-Woei Wang, Tzong-Ming Shieh, Tsui-Chin Huang, Li-Chun Lin, Kai-Lee Wang, and Shih-Min Hsia
73432-73447

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Lowdose salinomycin induces antileukemic responses in AML and MLL	Lowdose salinomycin induces antileukemic responses in AML and MLL
https://doi.org/10.18632/oncotarget.11866 Gary D.R. Roulston, Charlotte L. Burt, Laura M.J. Kettyle, Kyle B. Matchett, Heather L. Keenan, Nuala M. Mulgrew, Joanne M. Ramsey, Caoifa Dougan, John McKiernan, Ivan V. Grishagin, Ken I. Mills, and Alexander Thompson
73448-73461

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

GPR30 disrupts the balance of GABAergic and glutamatergic transmission in the spinal cord driving to the development of bone cancer pain	GPR30 disrupts the balance of GABAergic and glutamatergic transmission in the spinal cord driving to the development of bone cancer pain
https://doi.org/10.18632/oncotarget.11867 Jie Luo, Xiaoxia Huang, Yali Li, Yang Li, Xueqin Xu, Yan Gao, Ruoshi Shi, Wanjun Yao, Juying Liu, and Changbin Ke
73462-73472

Abstract  |  PDF  |  Full Text  |  How to cite

Recombinant human bone morphogenetic protein2 inhibits gastric cancer cell proliferation by inactivating Wnt signaling pathway via cMyc with aurora kinases	Recombinant human bone morphogenetic protein2 inhibits gastric cancer cell proliferation by inactivating Wnt signaling pathway via cMyc with aurora kinases
https://doi.org/10.18632/oncotarget.11969 Kwang Bok Lee, Hua Jin, Shuai Ye, Byung Hyun Park, and Soo Mi Kim
73473-73485

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Oxidized macrophage migration inhibitory factor is a potential new tissue marker and drug target in cancer	Oxidized macrophage migration inhibitory factor is a potential new tissue marker and drug target in cancer
https://doi.org/10.18632/oncotarget.11970 Alexander Schinagl, Michael Thiele, Patrice Douillard, Dirk Völkel, Lukas Kenner, Zahra Kazemi, Michael Freissmuth, Friedrich Scheiflinger, and Randolf J. Kerschbaumer
73486-73496

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Piperlongumine induces apoptosis and reduces bortezomib resistance by inhibiting STAT3 in multiple myeloma cells	Piperlongumine induces apoptosis and reduces bortezomib resistance by inhibiting STAT3 in multiple myeloma cells
https://doi.org/10.18632/oncotarget.11988 Yao Yao, Yueyue Sun, Min Shi, Dandan Xia, Kai Zhao, Lingyu Zeng, Ruosi Yao, Ying Zhang, Zhenyu Li, Mingshan Niu, and Kailin Xu
73497-73508

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Integrating microRNA and mRNA expression profiles of acute promyelocytic leukemia cells to explore the occurrence mechanisms of differentiation syndrome	Integrating microRNA and mRNA expression profiles of acute promyelocytic leukemia cells to explore the occurrence mechanisms of differentiation syndrome
https://doi.org/10.18632/oncotarget.11989 Yingmei Zhang, Jinxiao Hou, Fei Ge, Fenglin Cao, Haitao Li, Ping Wang, Mengyuan Xu, Peng Song, Xiaoxia Li, Shuye Wang, Jinmei Li, Xueying Han, Yanhong Zhao, Yanhua Su, Yinghua Li, Shengjin Fan, Limin Li, and Jin Zhou
73509-73524

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Lipid phosphatase SHIP2 functions as oncogene in colorectal cancer by regulating PKB activation	Lipid phosphatase SHIP2 functions as oncogene in colorectal cancer by regulating PKB activation
https://doi.org/10.18632/oncotarget.12321 Elmer Hoekstra, Asha M. Das, Marcella Willemsen, Marloes Swets, Peter J.K. Kuppen, Christien J. van der Woude, Marco J. Bruno, Jigisha P. Shah, Timo L.M. ten Hagen, John D. Chisholm, William G. Kerr, Maikel P. Peppelenbosch, and Gwenny M. Fuhler
73525-73540

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification of long noncoding RNAs biomarkers for early diagnosis of myocardial infarction from the dysregulated codingnoncoding coexpression network	Identification of long noncoding RNAs biomarkers for early diagnosis of myocardial infarction from the dysregulated codingnoncoding coexpression network
https://doi.org/10.18632/oncotarget.11999 Chaoyu Sun, Hao Jiang, Zhiguo Sun, Yifang Gui, and Hongyuan Xia
73541-73551

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Matrix metalloproteinase13 refines pathological staging of precancerous colorectal lesions	Matrix metalloproteinase13 refines pathological staging of precancerous colorectal lesions
https://doi.org/10.18632/oncotarget.12429 Anna-Katharina Wernicke, Yuri Churin, Diana Sheridan, Anita Windhorst, Annette Tschuschner, Stefan Gattenlöhner, Martin Roderfeld, and Elke Roeb
73552-73557

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

CCND1 mutations increase protein stability and promote ibrutinib resistance in mantle cell lymphoma	CCND1 mutations increase protein stability and promote ibrutinib resistance in mantle cell lymphoma
https://doi.org/10.18632/oncotarget.12434 Atish Mohanty, Natalie Sandoval, Manasi Das, Raju Pillai, Lu Chen, Robert W. Chen, Hesham M. Amin, Michael Wang, Guido Marcucci, Dennis D. Weisenburger, Steven T. Rosen, Lan V. Pham, and Vu N. Ngo
73558-73572

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Flavan3ols consumption and cancer risk: a metaanalysis of epidemiologic studies	Flavan3ols consumption and cancer risk: a metaanalysis of epidemiologic studies
https://doi.org/10.18632/oncotarget.12017 Lei Lei, Ying Yang, Hongiuan He, Erfei Chen, Le Du, Jing Dong, and Jin Yang
73573-73592

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

NRF2 promotes breast cancer cell proliferation and metastasis by increasing RhoA/ROCK pathway signal transduction	NRF2 promotes breast cancer cell proliferation and metastasis by increasing RhoA/ROCK pathway signal transduction
https://doi.org/10.18632/oncotarget.12435 Chao Zhang, Hui-Jie Wang, Qi-Chao Bao, Lei Wang, Tian-Kun Guo, Wei-Lin Chen, Li-Li Xu, Hai-Shan Zhou, Jin-Lei Bian, Ying-Rui Yang, Hao-Peng Sun, Xiao-Li Xu, and Qi-Dong You
73593-73606

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Chicken GHR natural antisense transcript regulates GHR mRNA in LMH cells	Chicken GHR natural antisense transcript regulates GHR mRNA in LMH cells
https://doi.org/10.18632/oncotarget.12437 Li Zhang, Shudai Lin, Lilong An, Jinge Ma, Fengfang Qiu, Rumin Jia, Qinghua Nie, Dexiang Zhang, Qingbin Luo, Ting Li, Zhang Wang, and Xiquan Zhang
73607-73617

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

AntiEGFR monoclonal antibodies and EGFR tyrosine kinase inhibitors as combination therapy for triplenegative breast cancer	AntiEGFR monoclonal antibodies and EGFR tyrosine kinase inhibitors as combination therapy for triplenegative breast cancer
https://doi.org/10.18632/oncotarget.12037 Abderrahim El Guerrab, Mahchid Bamdad, Fabrice Kwiatkowski, Yves-Jean Bignon, Frédérique Penault-Llorca, and Corinne Aubel
73618-73637

Abstract  |  PDF  |  Full Text  |  How to cite

Decreased expression of IDH1R132H correlates with poor survival in gastrointestinal cancer	Decreased expression of IDH1R132H correlates with poor survival in gastrointestinal cancer
https://doi.org/10.18632/oncotarget.12039 Jieying Li, Jianfei Huang, Fang Huang, Qing Jin, Huijun Zhu, Xudong Wang, and Meng Chen
73638-73650

Abstract  |  PDF  |  Full Text  |  How to cite

Locked nucleic acidinhibitor of miR205 decreases endometrial cancer cells proliferation in vitro and in vivo	Locked nucleic acidinhibitor of miR205 decreases endometrial cancer cells proliferation in vitro and in vivo
https://doi.org/10.18632/oncotarget.12043 Anna Torres, Joanna Kozak, Agnieszka Korolczuk, Dominika Rycak, Paulina Wdowiak, Ryszard Maciejewski, and Kamil Torres
73651-73663

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Uncovering synthetic lethal interactions for therapeutic targets and predictive markers in lung adenocarcinoma	Uncovering synthetic lethal interactions for therapeutic targets and predictive markers in lung adenocarcinoma
https://doi.org/10.18632/oncotarget.12046 Jan-Gowth Chang, Chia-Cheng Chen, Yi-Ying Wu, Ting-Fang Che, Yi-Syuan Huang, Kun-Tu Yeh, Grace S. Shieh, and Pan-Chyr Yang
73664-73680

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

AsnGlyArgmodified polydopaminecoated nanoparticles for dualtargeting therapy of brain glioma in rats	AsnGlyArgmodified polydopaminecoated nanoparticles for dualtargeting therapy of brain glioma in rats
https://doi.org/10.18632/oncotarget.12047 Jiangang Hu, Xiang Zhang, Zuhuang Wen, Ying Tan, Ning Huang, Si Cheng, Huzhi Zheng, and Yuan Cheng
73681-73696

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Secondgeneration proteasome inhibitor carfilzomib enhances doxorubicininduced cytotoxicity and apoptosis in breast cancer cells	Secondgeneration proteasome inhibitor carfilzomib enhances doxorubicininduced cytotoxicity and apoptosis in breast cancer cells
https://doi.org/10.18632/oncotarget.12048 Yonghua Shi, Yang Yu, Zhenyu Wang, Hao Wang, Shayahati Bieerkehazhi, Yanling Zhao, Lale Suzuk, and Hong Zhang
73697-73710

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Lipopolysaccharide increases the release of VEGFC that enhances cell motility and promotes lymphangiogenesis and lymphatic metastasis through the TLR4 NFκB/JNK pathways in colorectal cancer	Lipopolysaccharide increases the release of VEGFC that enhances cell motility and promotes lymphangiogenesis and lymphatic metastasis through the TLR4 NFκB/JNK pathways in colorectal cancer
https://doi.org/10.18632/oncotarget.12449 Guangwei Zhu, Qiang Huang, Yongjian Huang, Wei Zheng, Jin Hua, Shugang Yang, Jinfu Zhuang, Jinzhou Wang, and Jianxin Ye
73711-73724

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Role of BCL9L in transforming growth factorβ TGFβinduced epithelialtomesenchymaltransition EMT and metastasis of pancreatic cancer	Role of BCL9L in transforming growth factorβ TGFβinduced epithelialtomesenchymaltransition EMT and metastasis of pancreatic cancer
https://doi.org/10.18632/oncotarget.12455 Giuseppina Sannino, Nicole Armbruster, Mona Bodenhöfer, Ursula Haerle, Diana Behrens, Malte Buchholz, Ulrich Rothbauer, Bence Sipos, and Christian Schmees
73725-73738

Abstract  |  PDF  |  Full Text  |  How to cite

The other face of miR1792a cluster exhibiting tumor suppressor effects in prostate cancer	The other face of miR1792a cluster exhibiting tumor suppressor effects in prostate cancer
https://doi.org/10.18632/oncotarget.12061 Richard Ottman, Jenna Levy, Williams E. Grizzle, and Ratna Chakrabarti
73739-73753

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Bone morphogenetic protein9 is a potent growth inhibitor of hepatocellular carcinoma and reduces the liver cancer stem cells population	Bone morphogenetic protein9 is a potent growth inhibitor of hepatocellular carcinoma and reduces the liver cancer stem cells population
https://doi.org/10.18632/oncotarget.12062 Jae Woo Jung, So-Mi Yoon, Subin Kim, Yun-Hui Jeon, Byung-Hak Yoon, Su-Geun Yang, Min Kyoung Kim, Senyon Choe, and Mario Meng-Chiang Kuo
73754-73768

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Unique long noncoding RNA expression signature in ETV6/RUNX1driven Bcell precursor acute lymphoblastic leukemia	Unique long noncoding RNA expression signature in ETV6/RUNX1driven Bcell precursor acute lymphoblastic leukemia
https://doi.org/10.18632/oncotarget.12063 Farzaneh Ghazavi, Barbara De Moerloose, Wouter Van Loocke, Annelynn Wallaert, Hetty H. Helsmoortel, Alina Ferster, Marleen Bakkus, Geneviève Plat, Eric Delabesse, Anne Uyttebroeck, Filip Van Nieuwerburgh, Dieter Deforce, Nadine Van Roy, Frank Speleman, Yves Benoit, Tim Lammens, and Pieter Van Vlierberghe
73769-73780

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

TERT rs2853676 polymorphisms correlate with glioma prognosis in Chinese population	TERT rs2853676 polymorphisms correlate with glioma prognosis in Chinese population
https://doi.org/10.18632/oncotarget.12064 Xue He, Yahui Wei, Zhengshuai Chen, Xikai Zhu, Lifeng Ma, Ning Zhang, Yuan Zhang, Longli Kang, Dongya Yuan, Zongyong Zhang, and Tianbo Jin
73781-73791

Abstract  |  PDF  |  Full Text  |  How to cite

A dosimetric and treatment efficiency evaluation of stereotactic body radiation therapy for peripheral lung cancer using flattening filter free beams	A dosimetric and treatment efficiency evaluation of stereotactic body radiation therapy for peripheral lung cancer using flattening filter free beams
https://doi.org/10.18632/oncotarget.12071 Ji-Yong Zhang, Jia-Yang Lu, Li-Li Wu, Dan-Li Hong, Chang-chun Ma, Xun Peng, and Zhi-Xiong Lin
73792-73799

Abstract  |  PDF  |  Full Text  |  How to cite

Epithelial splicing regulatory protein 1 and 2 paralogues correlate with splice signatures and favorable outcome in human colorectal cancer	Epithelial splicing regulatory protein 1 and 2 paralogues correlate with splice signatures and favorable outcome in human colorectal cancer
https://doi.org/10.18632/oncotarget.12070 Abigail J. Deloria, Doris Höflmayer, Philip Kienzl, Justyna Łopatecka, Sandra Sampl, Martin Klimpfinger, Tamara Braunschmid, Fabienne Bastian, Lingeng Lu, Brigitte Marian, Stefan Stättner, and Klaus Holzmann
73800-73816

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

SHP2 phosphatase as a novel therapeutic target for melanoma treatment	SHP2 phosphatase as a novel therapeutic target for melanoma treatment
https://doi.org/10.18632/oncotarget.12074 Ruo-Yu Zhang, Zhi-Hong Yu, Lifan Zeng, Sheng Zhang, Yunpeng Bai, Jinmin Miao, Lan Chen, Jingwu Xie, and Zhong-Yin Zhang
73817-73829

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tetraspecific scFv construct provides NK cell mediated ADCC and selfsustaining stimuli via insertion of IL15 as a crosslinker	Tetraspecific scFv construct provides NK cell mediated ADCC and selfsustaining stimuli via insertion of IL15 as a crosslinker
https://doi.org/10.18632/oncotarget.12073 Joerg U. Schmohl, Martin Felices, Deborah Todhunter, Elizabeth Taras, Jeffrey S. Miller, and Daniel A. Vallera
73830-73844

Abstract  |  PDF  |  Full Text  |  How to cite

CoGAPS matrix factorization algorithm identifies transcriptional changes in AP2alpha target genes in feedback from therapeutic inhibition of the EGFR network	CoGAPS matrix factorization algorithm identifies transcriptional changes in AP2alpha target genes in feedback from therapeutic inhibition of the EGFR network
https://doi.org/10.18632/oncotarget.12075 Elana J. Fertig, Hiroyuki Ozawa, Manjusha Thakar, Jason D. Howard, Luciane T. Kagohara, Gabriel Krigsfeld, Ruchira S. Ranaweera, Robert M. Hughes, Jimena Perez, Siân Jones, Alexander V. Favorov, Jacob Carey, Genevieve Stein-O’Brien, Daria A. Gaykalova, Daria A. Gaykalova, Michael F. Ochs, and Christine H. Chung
73845-73864

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Novel lymph node ratio predicts prognosis of colorectal cancer patients after radical surgery when tumor deposits are counted as positive lymph nodes: a retrospective multicenter study	Novel lymph node ratio predicts prognosis of colorectal cancer patients after radical surgery when tumor deposits are counted as positive lymph nodes: a retrospective multicenter study
https://doi.org/10.18632/oncotarget.12076 Jin Yang, Shasha Xing, Jun Li, Shengke Yang, Junjie Hu, Hao Liu, Feng Du, Jie Yin, Sai Liu, Ci Li, Jiatian Yuan, and Bo Lv
73865-73875

Abstract  |  PDF  |  Full Text  |  How to cite

Genomic profiling of stage II and III colon cancers reveals APC mutations to be associated with survival in stage III colon cancer patients	Genomic profiling of stage II and III colon cancers reveals APC mutations to be associated with survival in stage III colon cancer patients
https://doi.org/10.18632/oncotarget.12510 Evert van den Broek, Oscar Krijgsman, Daoud Sie, Marianne Tijssen, Sandra Mongera, Mark A. van de Wiel, Eric J. Th. Belt, Sjoerd H. den Uil, Herman Bril, Hein B.A.C. Stockmann, Bauke Ylstra, Beatriz Carvalho, Gerrit A. Meijer, and Remond J.A. Fijneman
73876-73887

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miR285p acts as a tumor suppressor in renal cell carcinoma for multiple antitumor effects by targeting RAP1B	miR285p acts as a tumor suppressor in renal cell carcinoma for multiple antitumor effects by targeting RAP1B
https://doi.org/10.18632/oncotarget.12516 Cheng Wang, Caiyun Wu, Qi Yang, Meng Ding, Jinsha Zhong, Chen-Yu Zhang, Jingping Ge, Junjun Wang, and Chunni Zhang
73888-73902

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The impact of neuronal Notch1/JNK pathway on intracerebral hemorrhageinduced neuronal injury of rat model	The impact of neuronal Notch1/JNK pathway on intracerebral hemorrhageinduced neuronal injury of rat model
https://doi.org/10.18632/oncotarget.12094 Maohua Chen, Jun Sun, Chuan Lu, Xiandong Chen, Huajun Ba, Qun Lin, Jianyong Cai, and Junxia Dai
73903-73911

Abstract  |  PDF  |  Full Text  |  How to cite

Antibodybased PET of uPA/uPAR signaling with broad applicability for cancer imaging	Antibodybased PET of uPA/uPAR signaling with broad applicability for cancer imaging
https://doi.org/10.18632/oncotarget.12528 Dongzhi Yang, Gregory W. Severin, Casey A. Dougherty, Rachel Lombardi, Daiqin Chen, Marcian E. Van Dort, Todd E. Barnhart, Brian D. Ross, Andrew P. Mazar, and Hao Hong
73912-73924

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Transfer of functional microRNAs between glioblastoma and microvascular endothelial cells through gap junctions	Transfer of functional microRNAs between glioblastoma and microvascular endothelial cells through gap junctions
https://doi.org/10.18632/oncotarget.12136 Dominique Thuringer, Jonathan Boucher, Gaetan Jego, Nicolas Pernet, Laurent Cronier, Arlette Hammann, Eric Solary, and Carmen Garrido
73925-73934

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A PRISMAcompliant metaanalysis of MDM4 genetic variants and cancer susceptibility	A PRISMAcompliant metaanalysis of MDM4 genetic variants and cancer susceptibility
https://doi.org/10.18632/oncotarget.12558 Yajing Zhai, Zhijun Dai, Hairong He, Fan Gao, Lihong Yang, Yalin Dong, and Jun Lu
73935-73944

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A comprehensive metaanalysis of genetic associations between five key SNPs and colorectal cancer risk	A comprehensive metaanalysis of genetic associations between five key SNPs and colorectal cancer risk
https://doi.org/10.18632/oncotarget.12154 Yi Hong, Guoying Wu, Wei Li, Dahai Liu, and Kan He
73945-73959

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The tumorassociated antigen RHAMM HMMR/CD168 is expressed by monocytederived dendritic cells and presented to T cells	The tumorassociated antigen RHAMM HMMR/CD168 is expressed by monocytederived dendritic cells and presented to T cells
https://doi.org/10.18632/oncotarget.12170 Yannick Willemen, Johan M.J. Van den Bergh, Sarah M. Bonte, Sébastien Anguille, Carlo Heirman, Barbara M.H. Stein, Herman Goossens, Tessa Kerre, Kris Thielemans, Marc Peeters, Viggo F.I. Van Tendeloo, Evelien L.J. Smits, and Zwi N. Berneman
73960-73970

Abstract  |  PDF  |  Full Text  |  How to cite

Identification of a five B cellassociated gene prognostic and predictive signature for advanced glioma patients harboring immunosuppressive subtype preference	Identification of a five B cellassociated gene prognostic and predictive signature for advanced glioma patients harboring immunosuppressive subtype preference
https://doi.org/10.18632/oncotarget.12605 Chuanbao Zhang, Jiye Li, Haoyuan Wang, and Sonya Wei Song
73971-73983

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Circulating vascular endothelial growth factor VEGF as predictive factor of progressionfree survival in patients with advanced chordoma receiving sorafenib: an analysis from a phase II trial of the french sarcoma group GSF/GETO	Circulating vascular endothelial growth factor VEGF as predictive factor of progressionfree survival in patients with advanced chordoma receiving sorafenib: an analysis from a phase II trial of the french sarcoma group GSF/GETO
https://doi.org/10.18632/oncotarget.12172 Loic Lebellec, François Bertucci, Emmanuelle Tresch-Bruneel, Emmanuelle Bompas, Yves Toiron, Luc Camoin, Olivier Mir, Valerie Laurence, Stephanie Clisant, Emilie Decoupigny, Jean-Yves Blay, Anthony Goncalves, and Nicolas Penel
73984-73994

Abstract  |  PDF  |  Full Text  |  How to cite

Generation of affibody molecules specific for HPV16 E7 recognition	Generation of affibody molecules specific for HPV16 E7 recognition
https://doi.org/10.18632/oncotarget.12174 Xiangyang Xue, Bingbing Wang, Wangqi Du, Chanqiong Zhang, Yiling Song, Yiqi Cai, Danwei Cen, Ledan Wang, Yirong Xiong, Pengfei Jiang, Shanli Zhu, Kong-Nan Zhao, and Lifang Zhang
73995-74005

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Cystic brain metastasis is associated with poor prognosis in patients with advanced breast cancer	Cystic brain metastasis is associated with poor prognosis in patients with advanced breast cancer
https://doi.org/10.18632/oncotarget.12176 Bing Sun, Zhou Huang, Shikai Wu, Lijuan Ding, Ge Shen, Lei Cha, Junliang Wang, and Santai Song
74006-74014

Abstract  |  PDF  |  Full Text  |  How to cite

FGF4 induces epithelialmesenchymal transition by inducing storeoperated calcium entry in lung adenocarcinoma	FGF4 induces epithelialmesenchymal transition by inducing storeoperated calcium entry in lung adenocarcinoma
https://doi.org/10.18632/oncotarget.12187 Lisha Qi, Wangzhao Song, Lingmei Li, Lu Cao, Yue Yu, Chunmin Song, Yalei Wang, Fei Zhang, Yang Li, Bin Zhang, and Wenfeng Cao
74015-74030

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Classifying lower grade glioma cases according to whole genome gene expression	Classifying lower grade glioma cases according to whole genome gene expression
https://doi.org/10.18632/oncotarget.12188 Baoshi Chen, Tingyu Liang, Pei Yang, Haoyuan Wang, Yanwei Liu, Fan Yang, and Gan You
74031-74042

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Impact of HuR inhibition by the small molecule MS444 on colorectal cancer cell tumorigenesis	Impact of HuR inhibition by the small molecule MS444 on colorectal cancer cell tumorigenesis
https://doi.org/10.18632/oncotarget.12189 Fernando F. Blanco, Ranjan Preet, Andrea Aguado, Vikalp Vishwakarma, Laura E. Stevens, Alok Vyas, Subhash Padhye, Liang Xu, Scott J. Weir, Shrikant Anant, Nicole Meisner-Kober, Jonathan R. Brody, and Dan A. Dixon
74043-74058

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MicroRNA98 acts as a tumor suppressor in hepatocellular carcinoma via targeting SALL4	MicroRNA98 acts as a tumor suppressor in hepatocellular carcinoma via targeting SALL4
https://doi.org/10.18632/oncotarget.12190 Wuyuan Zhou, Benkui Zou, Lisheng Liu, Kai Cui, Jie Gao, Shuanghu Yuan, and Ning Cong
74059-74073

Abstract  |  PDF  |  Full Text  |  How to cite

Axillary and internal mammary sentinel lymph node biopsy in breast cancer after neoadjuvant chemotherapy	Axillary and internal mammary sentinel lymph node biopsy in breast cancer after neoadjuvant chemotherapy
https://doi.org/10.18632/oncotarget.12615 Xiao-Shan Cao, Hui-Juan Li, Bin-Bin Cong, Xiao Sun, Peng-Fei Qiu, Yan-Bing Liu, Chun-Jian Wang, and Yong-Sheng Wang
74074-74081

Abstract  |  PDF  |  Full Text  |  How to cite

Variable but consistent pattern of Meningioma 1 gene MN1 expression in different genetic subsets of acute myelogenous leukaemia and its potential use as a marker for minimal residual disease detection	Variable but consistent pattern of Meningioma 1 gene MN1 expression in different genetic subsets of acute myelogenous leukaemia and its potential use as a marker for minimal residual disease detection
https://doi.org/10.18632/oncotarget.12269 Sonia Carturan, Jessica Petiti, Valentina Rosso, Chiara Calabrese, Elisabetta Signorino, Giada Bot-Sartor, Paolo Nicoli, Daniela Gallo, Enrico Bracco, Alessandro Morotti, Cristina Panuzzo, Enrico Gottardi, Francesco Frassoni, Giuseppe Saglio, and Daniela Cilloni
74082-74096

Abstract  |  PDF  |  Full Text  |  How to cite

Somatic alterations of targetable oncogenes are frequently observed in BRCA1/2 mutation negative male breast cancers	Somatic alterations of targetable oncogenes are frequently observed in BRCA1/2 mutation negative male breast cancers
https://doi.org/10.18632/oncotarget.12272 Piera Rizzolo, Anna Sara Navazio, Valentina Silvestri, Virginia Valentini, Veronica Zelli, Ines Zanna, Giovanna Masala, Simonetta Bianchi, Marco Scarnò, Stefania Tommasi, Domenico Palli, and Laura Ottini
74097-74106

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Immune adjuvant effect of a Toxoplasma gondii profilinlike protein in autologous wholetumorcell vaccination in mice	Immune adjuvant effect of a Toxoplasma gondii profilinlike protein in autologous wholetumorcell vaccination in mice
https://doi.org/10.18632/oncotarget.12316 Kyoung-Ho Pyo, You-Won Lee, Sun Min Lim, and Eun-Hee Shin
74107-74119

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Exploring timing activation of functional pathway based on differential coexpression analysis in preimplantation embryogenesis	Exploring timing activation of functional pathway based on differential coexpression analysis in preimplantation embryogenesis
https://doi.org/10.18632/oncotarget.12339 Yongchun Zuo, Guanghua Su, Shanshan Wang, Lei Yang, Mingzhi Liao, Zhuying Wei, Chunling Bai, and Guangpeng Li
74120-74131

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Mitochondrial dysfunction enhances cisplatin resistance in human gastric cancer cells via the ROSactivated GCN2eIF2αATF4xCT pathway	Mitochondrial dysfunction enhances cisplatin resistance in human gastric cancer cells via the ROSactivated GCN2eIF2αATF4xCT pathway
https://doi.org/10.18632/oncotarget.12356 Sheng-Fan Wang, Meng-Shian Chen, Yueh-Ching Chou, Yune-Fang Ueng, Pen-Hui Yin, Tien-Shun Yeh, and Hsin-Chen Lee
74132-74151

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Cytomorphological characteristics of glassy cell carcinoma of the uterine cervix: histopathological correlation and human papillomavirus genotyping	Cytomorphological characteristics of glassy cell carcinoma of the uterine cervix: histopathological correlation and human papillomavirus genotyping
https://doi.org/10.18632/oncotarget.12361 Yoon Yang Jung, Ji Hae Nahm, and Hyun-Soo Kim
74152-74161

Abstract  |  PDF  |  Full Text  |  How to cite

Advanced lung adenocarcinomas with ROS1rearrangement frequently show hepatoid cell	Advanced lung adenocarcinomas with ROS1rearrangement frequently show hepatoid cell
https://doi.org/10.18632/oncotarget.12364 Jing Zhao, Jing Zheng, Mei Kong, Jianya Zhou, Wei Ding, and Jianying Zhou
74162-74170

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Engineering of double recombinant vaccinia virus with enhanced oncolytic potential for solid tumor virotherapy	Engineering of double recombinant vaccinia virus with enhanced oncolytic potential for solid tumor virotherapy
https://doi.org/10.18632/oncotarget.12367 Galina Kochneva, Galina Sivolobova, Anastasiya Tkacheva, Antonina Grazhdantseva, Olga Troitskaya, Anna Nushtaeva, Anastasiya Tkachenko, Elena Kuligina, Vladimir Richter, and Olga Koval
74171-74188

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prostatespecific membrane antigen PSMA assembles a macromolecular complex regulating growth and survival of prostate cancer cells “in vitro” and correlating with progression “in vivo”	Prostatespecific membrane antigen PSMA assembles a macromolecular complex regulating growth and survival of prostate cancer cells “in vitro” and correlating with progression “in vivo”
https://doi.org/10.18632/oncotarget.12404 Maria Elisa Perico, Silvia Grasso, Matteo Brunelli, Guido Martignoni, Enrico Munari, Enrico Moiso, Giulio Fracasso, Tiziana Cestari, Hassan Y. Naim, Vincenzo Bronte, Marco Colombatti, and Dunia Ramarli
74189-74202

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Low pH impairs complementdependent cytotoxicity against IgGcoated target cells	Low pH impairs complementdependent cytotoxicity against IgGcoated target cells
https://doi.org/10.18632/oncotarget.12412 Ezequiel Dantas, Fernando Erra Díaz, Pehuén Pereyra Gerber, Antonela Merlotti, Augusto Varese, Matías Ostrowski, Juan Sabatté, and Jorge Geffner
74203-74216

Abstract  |  PDF  |  Full Text  |  How to cite

MicroRNA126 affects rheumatoid arthritis synovial fibroblast proliferation and apoptosis by targeting PIK3R2 and regulating PI3KAKT signal pathway	MicroRNA126 affects rheumatoid arthritis synovial fibroblast proliferation and apoptosis by targeting PIK3R2 and regulating PI3KAKT signal pathway
https://doi.org/10.18632/oncotarget.12487 Yuan Qu, Jing Wu, Jia-Xin Deng, Yu-Ping Zhang, Wan-Yi Liang, Zhen-Lan Jiang, Qing-Hong Yu, and Juan Li
74217-74226

Abstract  |  PDF  |  Full Text  |  How to cite

Germline mutations in Japanese familial pancreatic cancer patients	Germline mutations in Japanese familial pancreatic cancer patients
https://doi.org/10.18632/oncotarget.12490 Erina Takai, Shinichi Yachida, Kyoko Shimizu, Junji Furuse, Emi Kubo, Akihiro Ohmoto, Masami Suzuki, Ralph H. Hruban, Takuji Okusaka, Chigusa Morizane, and Toru Furukawa
74227-74235

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Overexpression and potential roles of NRIP1 in psoriasis	Overexpression and potential roles of NRIP1 in psoriasis
https://doi.org/10.18632/oncotarget.12371 Chao Luan, Xu Chen, Yu Hu, Zhimin Hao, Jared M. Osland, Xundi Chen, Skyler D. Gerber, Min Chen, Heng Gu, and Rong Yuan
74236-74246

Abstract  |  PDF  |  Full Text  |  How to cite

Endotoxin promotes neutrophil hierarchical chemotaxis via the p38membrane receptor pathway	Endotoxin promotes neutrophil hierarchical chemotaxis via the p38membrane receptor pathway
https://doi.org/10.18632/oncotarget.12093 Xu Wang, Weiting Qin, Yisen Zhang, Huafeng Zhang, and Bingwei Sun
74247-74258

Abstract  |  PDF  |  Full Text  |  How to cite

A nextgeneration bifunctional photosensitizer with improved watersolubility for photodynamic therapy and diagnosis	A nextgeneration bifunctional photosensitizer with improved watersolubility for photodynamic therapy and diagnosis
https://doi.org/10.18632/oncotarget.12366 Hirotada Nishie, Hiromi Kataoka, Shigenobu Yano, Jun-ichi Kikuchi, Noriyuki Hayashi, Atsushi Narumi, Akihiro Nomoto, Eiji Kubota, and Takashi Joh
74259-74268

Abstract  |  PDF  |  Full Text  |  How to cite

Proteomic identification of the lactate dehydrogenase A in a radioresistant prostate cancer xenograft mouse model for improving radiotherapy	Proteomic identification of the lactate dehydrogenase A in a radioresistant prostate cancer xenograft mouse model for improving radiotherapy
https://doi.org/10.18632/oncotarget.12368 Jingli Hao, Peter Graham, Lei Chang, Jie Ni, Valerie Wasinger, Julia Beretov, Junli Deng, Wei Duan, Joseph Bucci, David Malouf, David Gillatt, and Yong Li
74269-74285

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinical Research Papers

Quantitative assessment of CD44 genetic variants and cancer susceptibility in Asians: a metaanalysis	Quantitative assessment of CD44 genetic variants and cancer susceptibility in Asians: a metaanalysis
https://doi.org/10.18632/oncotarget.10951 Vishal Chandra, Yun-Mi Lee, Usha Gupta, Balraj Mittal, Jong Joo Kim, and Rajani Rai
74286-74302

Abstract  |  PDF  |  Full Text  |  How to cite

Role of transarterial chemoembolization in relation with sorafenib for patients with advanced hepatocellular carcinoma	Role of transarterial chemoembolization in relation with sorafenib for patients with advanced hepatocellular carcinoma
https://doi.org/10.18632/oncotarget.11030 Yeonjung Ha, Danbi Lee, Ju Hyun Shim, Young-Suk Lim, Han Chu Lee, Young-Hwa Chung, Yung Sang Lee, Sook Ryun Park, Min-Hee Ryu, Baek-Yeol Ryoo, Yoon-Koo Kang, and Kang Mo Kim
74303-74313

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Preoperative neutrophiltolymphocyte ratio and tumorrelated factors to predict lymph node metastasis in patients with pancreatic ductal adenocarcinoma PDAC	Preoperative neutrophiltolymphocyte ratio and tumorrelated factors to predict lymph node metastasis in patients with pancreatic ductal adenocarcinoma PDAC
https://doi.org/10.18632/oncotarget.11031 Lianyuan Tao, Lingfu Zhang, Ying Peng, Ming Tao, Gang Li, Dianrong Xiu, Chunhui Yuan, Chaolai Ma, and Bin Jiang
74314-74324

Abstract  |  PDF  |  Full Text  |  How to cite

LncRNAs act as prognostic and diagnostic biomarkers in renal cell carcinoma: a systematic review and metaanalysis	LncRNAs act as prognostic and diagnostic biomarkers in renal cell carcinoma: a systematic review and metaanalysis
https://doi.org/10.18632/oncotarget.11101 Jianwen Chen, Yalei Chen, Liangyou Gu, Xintao Li, Yu Gao, Xiangjun Lyu, Luyao Chen, Guoxiong Luo, Lei Wang, Yongpeng Xie, Junyao Duan, Cheng Peng, and Xin Ma
74325-74336

Abstract  |  PDF  |  Full Text  |  How to cite

Lymph node ratiobased staging system as an alternative to the current TNM staging system to assess outcome in adenocarcinoma of the esophagogastric junction after surgical resection	Lymph node ratiobased staging system as an alternative to the current TNM staging system to assess outcome in adenocarcinoma of the esophagogastric junction after surgical resection
https://doi.org/10.18632/oncotarget.11188 Hongdian Zhang, Xiaobin Shang, Chuangui Chen, Yongyin Gao, Xiangming Xiao, Peng Tang, Xiaofeng Duan, Mingjian Yang, Hongjing Jiang, and Zhentao Yu
74337-74349

Abstract  |  PDF  |  Full Text  |  How to cite

Reviews

The efficacy and potential predictive factors of PD1/PDL1 blockades in epithelial carcinoma patients: a systematic review and meta analysis	The efficacy and potential predictive factors of PD1/PDL1 blockades in epithelial carcinoma patients: a systematic review and meta analysis
https://doi.org/10.18632/oncotarget.11291 Yufan Yang, ZhaoFei Pang, Nan Ding, Wei Dong, Wei Ma, Yun Li, Jiajun Du, and Qi Liu
74350-74361

Abstract  |  PDF  |  Full Text  |  How to cite

Prognostic and predictive value of EGFR in head and neck squamous cell carcinoma	Prognostic and predictive value of EGFR in head and neck squamous cell carcinoma
https://doi.org/10.18632/oncotarget.11413 Paolo Bossi, Carlo Resteghini, Nicholas Paielli, Lisa Licitra, Silvana Pilotti, and Federica Perrone
74362-74379

Abstract  |  PDF  |  Full Text  |  How to cite

Discovery and clinical introduction of firstinclass imipridone ONC201	Discovery and clinical introduction of firstinclass imipridone ONC201
https://doi.org/10.18632/oncotarget.11814 Joshua E. Allen, C. Leah B. Kline, Varun V. Prabhu, Jessica Wagner, Jo Ishizawa, Neel Madhukar, Avital Lev, Marie Baumeister, Lanlan Zhou, Amriti Lulla, Martin Stogniew, Lee Schalop, Cyril Benes, Howard L. Kaufman, Richard S. Pottorf, B. Rao Nallaganchu, Gary L. Olson, Fahd Al-Mulla, Madeleine Duvic, Gen Sheng Wu, David T. Dicker, Mala K. Talekar, Bora Lim, Olivier Elemento, Wolfgang Oster, Joseph Bertino, Keith Flaherty, Michael L. Wang, Gautam Borthakur, Michael Andreeff, Mark Stein, and Wafik S. El-Deiry
74380-74392

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ISG15 in the tumorigenesis and treatment of cancer: An emerging role in malignancies of the digestive system	ISG15 in the tumorigenesis and treatment of cancer: An emerging role in malignancies of the digestive system
https://doi.org/10.18632/oncotarget.11911 Chaohui Zuo, Xinyi Sheng, Min Ma, Man Xia, and Linda Ouyang
74393-74409

Abstract  |  PDF  |  Full Text  |  How to cite

Case Reports

Young patient with arterial thrombosis and skin changes as the onset manifestations: POEMS syndrome	Young patient with arterial thrombosis and skin changes as the onset manifestations: POEMS syndrome
https://doi.org/10.18632/oncotarget.12570 Ting-Ting Han, Shuang Zheng, Zeng-Ai Chen, Wei Liu, and Yao-Min Hu
74410-74414

Abstract  |  PDF  |  Full Text  |  How to cite

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