Priority Research Papers

Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with risk of clear cell ovarian cancer	Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with risk of clear cell ovarian cancer
https://doi.org/10.18632/oncotarget.10215 Shalaka S. Hampras, Lara E. Sucheston-Campbell, Rikki Cannioto, Jenny Chang-Claude, Francesmary Modugno, Thilo Dörk, Peter Hillemanns, Leah Preus, Keith L. Knutson, Paul K. Wallace, Chi-Chen Hong, Grace Friel, Warren Davis, Mary Nesline, Celeste L. Pearce, Linda E. Kelemen, Marc T. Goodman, Elisa V. Bandera, Kathryn L. Terry, Nils Schoof, Kevin H. Eng, Alyssa Clay, Prashant K. Singh, Janine M. Joseph, Katja K.H. Aben, Hoda Anton-Culver, Natalia Antonenkova, Helen Baker, Yukie Bean, Matthias W. Beckmann, Maria Bisogna, Line Bjorge, Natalia Bogdanova, Louise A. Brinton, Angela Brooks-Wilson, Fiona Bruinsma, Ralf Butzow, Ian G. Campbell, Karen Carty, Linda S. Cook, Daniel W. Cramer, Cezary Cybulski, Agnieszka Dansonka-Mieszkowska, Joe Dennis, Evelyn Despierre, Ed Dicks, Jennifer A. Doherty, Andreas du Bois, Matthias Dürst, Doug Easton, Diana Eccles, Robert P. Edwards, Arif B. Ekici, Peter A. Fasching, Brooke L. Fridley, Yu-Tang Gao, Aleksandra Gentry-Maharaj, Graham G. Giles, Rosalind Glasspool, Jacek Gronwald, Patricia Harrington, Philipp Harter, Hanis Nazihah Hasmad, Alexander Hein, Florian Heitz, Michelle A.T. Hildebrandt, Claus Hogdall, Estrid Hogdall, Satoyo Hosono, Edwin S. Iversen, Anna Jakubowska, Allan Jensen, Bu-Tian Ji, Beth Y. Karlan, Melissa Kellar, Joseph L. Kelley, Lambertus A. Kiemeney, Rüdiger Klapdor, Nonna Kolomeyevskaya, Camilla Krakstad, Susanne K. Kjaer, Bridget Kruszka, Jolanta Kupryjanczyk, Diether Lambrechts, Sandrina Lambrechts, Nhu D. Le, Alice W. Lee, Shashikant Lele, Arto Leminen, Jenny Lester, Douglas A. Levine, Dong Liang, Jolanta Lissowska, Song Liu, Karen Lu, Jan Lubinski, Lene Lundvall, Leon F.A.G. Massuger, Keitaro Matsuo, Valeria McGuire, John R. McLaughlin, Ian McNeish, Usha Menon, Joanna Moes-Sosnowska, Steven A. Narod, Lotte Nedergaard, Heli Nevalinna, Stefan Nickels, Lotte Nedergaard, Heli Nevanlinna, Stefan Nickels, Sara H. Olson, Irene Orlow, Rachel Palmieri Weber, James Paul, Tanja Pejovic, Liisa M. Pelttari, Barbara Perkins, Jenny Permuth-Wey, Malcolm C. Pike, Joanna Plisiecka-Halasa, Elizabeth M. Poole, Harvey A. Risch, Mary Anne Rossing, Joseph H. Rothstein, Anja Rudolph, Ingo B. Runnebaum, Iwona K. Rzepecka, Helga B. Salvesen, Eva Schernhammer, Kristina Schmitt, Ira Schwaab, Xiao-Ou Shu, Yurii B. Shvetsov, Nadeem Siddiqui, Weiva Sieh, Honglin Song, Melissa C. Southey, Ingvild L. Tangen, Soo-Hwang Teo, Pamela J. Thompson, Agnieszka Timorek, Ya-Yu Tsai, Shelley S. Tworoger, Jonathan Tyrer, Anna M. van Altena, Ignace Vergote, Robert A. Vierkant, Christine Walsh, Shan Wang-Gohrke, Nicolas Wentzensen, Alice S. Whittemore, Kristine G. Wicklund, Lynne R. Wilkens, Anna H. Wu, Xifeng Wu, Yin-Ling Woo, Hannah Yang, Wei Zheng, Argyrios Ziogas, Simon A. Gayther, Susan J. Ramus, Thomas A. Sellers, Joellen M. Schildkraut, Catherine M. Phelan, Andrew Berchuck, Georgia Chenevix-Trench, Julie M. Cunningham, Paul P. Pharoah, Roberta B. Ness, Kunle Odunsi, Ellen L. Goode, and Kirsten B. Moysich
69097-69110

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Defining the transcriptional and biological response to CDK4/6 inhibition in relation to ER+/HER2 breast cancer	Defining the transcriptional and biological response to CDK4/6 inhibition in relation to ER+/HER2 breast cancer
https://doi.org/10.18632/oncotarget.11588 Erik S. Knudsen, and Agnieszka K. Witkiewicz
69111-69123

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Dnmt3a deletion cooperates with the Flt3/ITD mutation to drive leukemogenesis in a murine model	Dnmt3a deletion cooperates with the Flt3/ITD mutation to drive leukemogenesis in a murine model
https://doi.org/10.18632/oncotarget.11986 Jennifer L. Poitras, Diane Heiser, Li Li, Bao Nguyen, Kozo Nagai, Amy S. Duffield, Christopher Gamper, and Donald Small
69124-69135

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Native and bone marrowderived cell mosaicism in gastric carcinoma in H pyloriinfected p27deficient mice	Native and bone marrowderived cell mosaicism in gastric carcinoma in H pyloriinfected p27deficient mice
https://doi.org/10.18632/oncotarget.12049 Songhua Zhang, Woojin Kim, Tu T. Pham, Arlin B. Rogers, Jean Marie Houghton, and Steven F. Moss
69136-69148

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Targeting the ERK pathway for the treatment of Cushing’s disease	Targeting the ERK pathway for the treatment of Cushing’s disease
https://doi.org/10.18632/oncotarget.12381 Dongyun Zhang, Marvin Bergsneider, Marilene B. Wang, and Anthony P. Heaney
69149-69158

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RGS6 is an essential tumor suppressor that prevents bladder carcinogenesis by promoting p53 activation and DNMT1 downregulation	RGS6 is an essential tumor suppressor that prevents bladder carcinogenesis by promoting p53 activation and DNMT1 downregulation
https://doi.org/10.18632/oncotarget.12473 Jianqi Yang, Lance T. Platt, Biswanath Maity, Katelin E. Ahlers, Zili Luo, Zhibo Lin, Bandana Chakravarti, Stella-Rita Ibeawuchi, Ryan W. Askeland, Jolanta Bondaruk, Bogdan A. Czerniak, and Rory A. Fisher
69159-69172

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IKK/NFκB signaling contributes to glioblastoma stem cell maintenance	IKK/NFκB signaling contributes to glioblastoma stem cell maintenance
https://doi.org/10.18632/oncotarget.12507 Amanda L. Rinkenbaugh, Patricia C. Cogswell, Barbara Calamini, Denise E. Dunn, Anders I. Persson, William A. Weiss, Donald C. Lo, and Albert S. Baldwin
69173-69187

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Research Papers: Gerotarget (Focus on Aging)

Mutational load and mutational patterns in relation to age in head and neck cancer	Mutational load and mutational patterns in relation to age in head and neck cancer
https://doi.org/10.18632/oncotarget.11312 Stefano Meucci, Ulrich Keilholz, Ingeborg Tinhofer, and Oliva A. Ebner
69188-69199

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Reduced bone resorption by intake of dietary vitamin D and K from tailormade Atlantic salmon: a randomized intervention trial	Reduced bone resorption by intake of dietary vitamin D and K from tailormade Atlantic salmon: a randomized intervention trial
https://doi.org/10.18632/oncotarget.10171 Ingvild Eide Graff, Jannike Øyen, Marian Kjellevold, Livar Frøyland, Clara Gram Gjesdal, Bjørg Almås, Grethe Rosenlund, and Øyvind Lie
69200-69215

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The effect of the severity of obstructive sleep apnea syndrome on telomere length	The effect of the severity of obstructive sleep apnea syndrome on telomere length
https://doi.org/10.18632/oncotarget.12293 Priscila Farias Tempaku, Diego Robles Mazzotti, Camila Hirotsu, Monica Levy Andersen, Gabriela Xavier, Pawan Kumar Maurya, Lucas Bortolotto Rizzo, Elisa Brietzke, Sintia Iole Belangero, Lia Bittencourt, and Sergio Tufik
69216-69224

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INPP5D rs35349669 polymorphism with lateonset Alzheimer’s disease: A replication study and metaanalysis	INPP5D rs35349669 polymorphism with lateonset Alzheimer’s disease: A replication study and metaanalysis
https://doi.org/10.18632/oncotarget.12648 Hua Jing, Jun-Xia Zhu, Hui-Fu Wang, Wei Zhang, Zhan-Jie Zheng, Ling-Li Kong, Chen-Chen Tan, Zi-Xuan Wang, Lin Tan, and Lan Tan
69225-69230

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Research Papers: Pathology

Fibroblast growth factor 23 dysregulates late sodium current and calcium homeostasis with enhanced arrhythmogenesis in pulmonary vein cardiomyocytes	Fibroblast growth factor 23 dysregulates late sodium current and calcium homeostasis with enhanced arrhythmogenesis in pulmonary vein cardiomyocytes
https://doi.org/10.18632/oncotarget.12470 Shih-Yu Huang, Yao-Chang Chen, Yu-Hsun Kao, Ming-Hsiung Hsieh, Yung-Kuo Lin, Cheng-Chih Chung, Ting-I Lee, Wen-Chin Tsai, Shih-Ann Chen, and Yi-Jen Chen
69231-69242

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Nitric oxide PKCε and connexin43 are crucial for ischemic preconditioninginduced chemical gap junction uncoupling	Nitric oxide PKCε and connexin43 are crucial for ischemic preconditioninginduced chemical gap junction uncoupling
https://doi.org/10.18632/oncotarget.12087 Bing Rong, Fei Xie, Tao Sun, Li Hao, Ming-Jie Lin, and Jing-Quan Zhong
69243-69255

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Delineation of the central melanocortin circuitry controlling the kidneys by a virally mediated transsynaptic tracing study in transgenic mouse model	Delineation of the central melanocortin circuitry controlling the kidneys by a virally mediated transsynaptic tracing study in transgenic mouse model
https://doi.org/10.18632/oncotarget.11956 Tao Tao Liu, Bao Wen Liu, Zhi Gang He, Li Feng, San Guang Liu, and Hong Bing Xiang
69256-69266

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Frequent somatic TERT promoter mutations and CTNNB1 mutations in hepatocellular carcinoma	Frequent somatic TERT promoter mutations and CTNNB1 mutations in hepatocellular carcinoma
https://doi.org/10.18632/oncotarget.12121 Seung Eun Lee, Seong-Hwan Chang, Wook Youn Kim, So Dug Lim, Wan Seop Kim, Tea Sook Hwang, and Hye Seung Han
69267-69275

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Signaling through hepatocyte vasopressin receptor 1 protects mouse liver from ischemiareperfusion injury	Signaling through hepatocyte vasopressin receptor 1 protects mouse liver from ischemiareperfusion injury
https://doi.org/10.18632/oncotarget.12472 Xiqiang Liu, Gaojian Luo, Jingbo Jiang, Tonghui Ma, Xiaozhu Lin, Liping Jiang, Jilin Cheng, and Ran Tao
69276-69290

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Pharmacological targeting of BET proteins inhibits renal fibroblast activation and alleviates renal fibrosis	Pharmacological targeting of BET proteins inhibits renal fibroblast activation and alleviates renal fibrosis
https://doi.org/10.18632/oncotarget.12498 Chongxiang Xiong, Monica V. Masucci, Xiaoxu Zhou, Na Liu, Xiujuan Zang, Evelyn Tolbert, Ting C. Zhao, and Shougang Zhuang
69291-69308

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Overexpressed cyclophilin B suppresses aldosteroneinduced proximal tubular cell injury both in vitro and in vivo	Overexpressed cyclophilin B suppresses aldosteroneinduced proximal tubular cell injury both in vitro and in vivo
https://doi.org/10.18632/oncotarget.12503 Bin Wang, Lilu Lin, Haidong Wang, Honglei Guo, Yong Gu, and Wei Ding
69309-69320

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SIRT3 is attenuated in systemic sclerosis skin and lungs and its pharmacologic activation mitigates organ fibrosis	SIRT3 is attenuated in systemic sclerosis skin and lungs and its pharmacologic activation mitigates organ fibrosis
https://doi.org/10.18632/oncotarget.12504 Kaname Akamata, Jun Wei, Mitra Bhattacharyya, Paul Cheresh, Michael Y. Bonner, Jack L. Arbiser, Kirtee Raparia, Mahesh P. Gupta, David W. Kamp, and John Varga
69321-69336

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Movement deficits and neuronal loss in basal ganglia in TRPC1 deficient mice	Movement deficits and neuronal loss in basal ganglia in TRPC1 deficient mice
https://doi.org/10.18632/oncotarget.12567 Kaiwu He, Fei Qi, Chunni Guo, Shuqin Zhan, Hua Xu, Jianjun Liu, and Xifei Yang
69337-69346

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Research Papers: Immunology

Neuroprotective effects of CD4+CD25+Foxp3+ regulatory T cells in a 3xTgAD Alzheimer’s disease model	Neuroprotective effects of CD4+CD25+Foxp3+ regulatory T cells in a 3xTgAD Alzheimer’s disease model
https://doi.org/10.18632/oncotarget.12469 Hyunjung Baek, Minsook Ye, Geun-Hyung Kang, Chanju Lee, Gihyun Lee, Da Bin Choi, Jaehoon Jung, Hyunseong Kim, Seonhwa Lee, Jin Su Kim, Hyun-ju Lee, Insop Shim, Jun-Ho Lee, and Hyunsu Bae
69347-69357

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Nucleoside 5’Omonophosphorothioates as modulators of the P2Y14 receptor and mast cell degranulation	Nucleoside 5’Omonophosphorothioates as modulators of the P2Y14 receptor and mast cell degranulation
https://doi.org/10.18632/oncotarget.12541 Edyta Gendaszewska-Darmach, Edyta Węgłowska, Aurelia Walczak-Drzewiecka, and Kaja Karaś
69358-69370

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Blocking TCR restimulation induced necroptosis in adoptively transferred T cells improves tumor control	Blocking TCR restimulation induced necroptosis in adoptively transferred T cells improves tumor control
https://doi.org/10.18632/oncotarget.12674 Pravin Kesarwani, Paramita Chakraborty, Radhika Gudi, Shilpak Chatterjee, Gina Scurti, Kyle Toth, Patt Simms, Mahvash Husain, Kent Armeson, Shahid Husain, Elizabeth Garrett-Mayer, Chethamarakshan Vasu, Michael I. Nishimura, and Shikhar Mehrotra
69371-69383

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Research Papers

Functional genetic variant in the Kozak sequence of WW domaincontaining oxidoreductase WWOX gene is associated with oral cancer risk	Functional genetic variant in the Kozak sequence of WW domaincontaining oxidoreductase WWOX gene is associated with oral cancer risk
https://doi.org/10.18632/oncotarget.12082 Hsin-Lin Cheng, Yu-Fan Liu, Chun-Wen Su, Shih-Chi Su, Mu-Kuan Chen, Shun-Fa Yang, and Chiao-Wen Lin
69384-69396

Abstract  |  PDF  |  Full Text  |  How to cite

Implication of NPM1 phosphorylation and preclinical evaluation of the nucleoprotein antagonist N6L in prostate cancer	Implication of NPM1 phosphorylation and preclinical evaluation of the nucleoprotein antagonist N6L in prostate cancer
https://doi.org/10.18632/oncotarget.8043 Damien Destouches, Maha Sader, Stéphane Terry, Charles Marchand, Pascale Maillé, Pascale Soyeux, Gilles Carpentier, Fannie Semprez, Jocelyn Céraline, Yves Allory, José Courty, Alexandre De La Taille, and Francis Vacherot
69397-69411

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Imatinib dose escalation versus sunitinib as a second line treatment in KIT exon 11 mutated GIST: a retrospective analysis	Imatinib dose escalation versus sunitinib as a second line treatment in KIT exon 11 mutated GIST: a retrospective analysis
https://doi.org/10.18632/oncotarget.5136 Bruno Vincenzi, Margherita Nannini, Elena Fumagalli, Giuseppe Bronte, Anna Maria Frezza, Delia De Lisi, Mariella Spalato Ceruso, Daniele Santini, Giuseppe Badalamenti, Maria Abbondanza Pantaleo, Antonio Russo, Angelo Paolo Dei Tos, Paolo Casali, and Giuseppe Tonini
69412-69419

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Novel antibody probes for the characterization of endosialin/TEM1	Novel antibody probes for the characterization of endosialin/TEM1
https://doi.org/10.18632/oncotarget.11018 Daniel J. O’Shannessy, Michael F. Smith, Elizabeth B. Somers, Stephen M. Jackson, Earl Albone, Brian Tomkowicz, Xin Cheng, Young Park, Danielle Fernando, Andrew Milinichik, Brad Kline, Regan Fulton, Pankaj Oberoi, and Nicholas C. Nicolaides
69420-69435

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TNFSF15 suppresses VEGF production in endothelial cells by stimulating miR29b expression via activation of JNKGATA3 signals	TNFSF15 suppresses VEGF production in endothelial cells by stimulating miR29b expression via activation of JNKGATA3 signals
https://doi.org/10.18632/oncotarget.11683 Kun Zhang, Hong-Xing Cai, Shan Gao, Gui-Li Yang, Hui-Ting Deng, Guo-Ce Xu, Jihong Han, Qiang-Zhe Zhang, and Lu-Yuan Li
69436-69449

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Oncogenic function and clinical implications of SLC3A2NRG1 fusion in invasive mucinous adenocarcinoma of the lung	Oncogenic function and clinical implications of SLC3A2NRG1 fusion in invasive mucinous adenocarcinoma of the lung
https://doi.org/10.18632/oncotarget.11913 Dong Hoon Shin, Donghoon Lee, Dong Wan Hong, Seung Hyun Hong, Jung-Ah Hwang, Byung Il Lee, Hye Jin You, Geon Kook Lee, In-Hoo Kim, Yeon-Su Lee, and Ji-Youn Han
69450-69465

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GBMassociated mutations and altered protein expression are more common in young patients	GBMassociated mutations and altered protein expression are more common in young patients
https://doi.org/10.18632/oncotarget.11617 Sherise D. Ferguson, Joanne Xiu, Shiao-Pei Weathers, Shouhao Zhou, Santosh Kesari, Stephanie E. Weiss, Roeland G. Verhaak, Raymond J. Hohl, Geoffrey R. Barger, Sandeep K. Reddy, and Amy B. Heimberger
69466-69478

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Important role of kallikrein 6 for the development of keratinocyte proliferative resistance to topical glucocorticoids	Important role of kallikrein 6 for the development of keratinocyte proliferative resistance to topical glucocorticoids
https://doi.org/10.18632/oncotarget.9926 Mari Kishibe, Gleb Baida, Pankaj Bhalla, Robert M. Lavker, Bethanee Schlosser, Sin Iinuma, Shigetaka Yoshida, Joel T. Dudley, and Irina Budunova
69479-69488

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Novel regulatory role of neuropilin1 in endothelialtomesenchymal transition and fibrosis in pancreatic ductal adenocarcinoma	Novel regulatory role of neuropilin1 in endothelialtomesenchymal transition and fibrosis in pancreatic ductal adenocarcinoma
https://doi.org/10.18632/oncotarget.11060 Pratiek N. Matkar, Krishna Kumar Singh, Dmitriy Rudenko, Yu Jin Kim, Michael A. Kuliszewski, Gerald J. Prud’homme, David W. Hedley, and Howard Leong-Poi
69489-69506

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Circulating tumor cells: A promising marker of predicting tumor response in rectal cancer patients receiving neoadjuvant chemoradiation therapy	Circulating tumor cells: A promising marker of predicting tumor response in rectal cancer patients receiving neoadjuvant chemoradiation therapy
https://doi.org/10.18632/oncotarget.10875 Wenjie Sun, Guichao Li, Juefeng Wan, Ji Zhu, Weiqi Shen, and Zhen Zhang
69507-69517

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Targeting hexokinase 2 enhances response to radiochemotherapy in glioblastoma	Targeting hexokinase 2 enhances response to radiochemotherapy in glioblastoma
https://doi.org/10.18632/oncotarget.11680 Alenoush Vartanian, Sameer Agnihotri, Mark R. Wilson, Kelly E. Burrell, Peter D. Tonge, Amir Alamsahebpour, Shahrzad Jalali, Michael S. Taccone, Sheila Mansouri, Brian Golbourn, Kenneth D. Aldape, and Gelareh Zadeh
69518-69535

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MXD1 localizes in the nucleolus binds UBF and impairs rRNA synthesis	MXD1 localizes in the nucleolus binds UBF and impairs rRNA synthesis
https://doi.org/10.18632/oncotarget.11766 Maria del Carmen Lafita-Navarro, Rosa Blanco, Jorge Mata-Garrido, Judit Liaño-Pons, Olga Tapia, Lucía García-Gutiérrez, Eva García-Alegría, María T. Berciano, Miguel Lafarga, and Javier León
69536-69548

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The dominantnegative interplay between p53 p63 and p73: A family affair	The dominantnegative interplay between p53 p63 and p73: A family affair
https://doi.org/10.18632/oncotarget.11774 Olivier Billant, Alice Léon, Solenn Le Guellec, Gaëlle Friocourt, Marc Blondel, and Cécile Voisset
69549-69564

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Urokinasetype plasminogen activator receptor promotes proliferation and invasion with reduced cisplatin sensitivity in malignant mesothelioma	Urokinasetype plasminogen activator receptor promotes proliferation and invasion with reduced cisplatin sensitivity in malignant mesothelioma
https://doi.org/10.18632/oncotarget.11829 Shenqi Wang, Li Jiang, Yipeng Han, Shan Hwu Chew, Yuuki Ohara, Shinya Akatsuka, Liang Weng, Koji Kawaguchi, Takayuki Fukui, Yoshitaka Sekido, Kohei Yokoi, and Shinya Toyokuni
69565-69578

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Epigenomewide association study of smoking and DNA methylation in nonsmall cell lung neoplasms	Epigenomewide association study of smoking and DNA methylation in nonsmall cell lung neoplasms
https://doi.org/10.18632/oncotarget.11831 Joshua R Freeman, Su Chu, Thomas Hsu, and Yen-Tsung Huang
69579-69591

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

EPRS is a critical regulator of cell proliferation and estrogen signaling in ER+ breast cancer	EPRS is a critical regulator of cell proliferation and estrogen signaling in ER+ breast cancer
https://doi.org/10.18632/oncotarget.11870 Igor Katsyv, Minghui Wang, Won Min Song, Xianxiao Zhou, Yongzhong Zhao, Sun Park, Jun Zhu, Bin Zhang, and Hanna Y. Irie
69592-69605

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Assessment of bevacizumab resistance increased by expression of BCAT1 in IDH1 wildtype glioblastoma: application of DSC perfusion MR imaging	Assessment of bevacizumab resistance increased by expression of BCAT1 in IDH1 wildtype glioblastoma: application of DSC perfusion MR imaging
https://doi.org/10.18632/oncotarget.11901 Hye Rim Cho, Bora Hong, Hyeonjin Kim, Chul-Kee Park, Sung-Hye Park, Sunghyouk Park, and Seung Hong Choi
69606-69615

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A panel of 13miRNA signature as a potential biomarker for predicting survival in pancreatic cancer	A panel of 13miRNA signature as a potential biomarker for predicting survival in pancreatic cancer
https://doi.org/10.18632/oncotarget.11903 Xin Zhou, Zebo Huang, Lei Xu, Mingxia Zhu, Lan Zhang, Huo Zhang, Xiaping Wang, Hai Li, Wei Zhu, Yongqian Shu, and Ping Liu
69616-69624

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The pathophysiological significance of PPM1D and therapeutic targeting of PPM1Dmediated signaling by GSK2830371 in mantle cell lymphoma	The pathophysiological significance of PPM1D and therapeutic targeting of PPM1Dmediated signaling by GSK2830371 in mantle cell lymphoma
https://doi.org/10.18632/oncotarget.11904 Kensuke Kojima, Aya Maeda, Mariko Yoshimura, Yuki Nishida, and Shinya Kimura
69625-69637

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Mutational burdens and evolutionary ages of thyroid follicular adenoma are comparable to those of follicular carcinoma	Mutational burdens and evolutionary ages of thyroid follicular adenoma are comparable to those of follicular carcinoma
https://doi.org/10.18632/oncotarget.11922 Seung-Hyun Jung, Min Sung Kim, Chan Kwon Jung, Hyun-Chun Park, So Youn Kim, Jieying Liu, Ja-Seong Bae, Sung Hak Lee, Tae-Min Kim, Sug Hyung Lee, and Yeun-Jun Chung
69638-69648

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CDCP1 is a novel marker of the most aggressive human triplenegative breast cancers	CDCP1 is a novel marker of the most aggressive human triplenegative breast cancers
https://doi.org/10.18632/oncotarget.11935 Federica Turdo, Francesca Bianchi, Patrizia Gasparini, Marco Sandri, Marianna Sasso, Loris De Cecco, Luca Forte, Patrizia Casalini, Piera Aiello, Lucia Sfondrini, Roberto Agresti, Maria Luisa Carcangiu, Ilaria Plantamura, Gabriella Sozzi, Elda Tagliabue, and Manuela Campiglio
69649-69665

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Prognostic significance of osteopontin expression in gastric cancer: a metaanalysis	Prognostic significance of osteopontin expression in gastric cancer: a metaanalysis
https://doi.org/10.18632/oncotarget.11936 Xiaobin Gu, Xian-Shu Gao, Mingwei Ma, Shangbin Qin, Xin Qi, Xiaoying Li, Shaoqian Sun, Hao Yu, Wen Wang, and Dong Zhou
69666-69673

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DOT1L promotes angiogenesis through cooperative regulation of VEGFR2 with ETS1	DOT1L promotes angiogenesis through cooperative regulation of VEGFR2 with ETS1
https://doi.org/10.18632/oncotarget.11939 Yang Duan, Xue Wu, Qiang Zhao, Jie Gao, Dawei Huo, Xinhua Liu, Zheng Ye, Xu Dong, Zheng Fu, Yongfeng Shang, and Chenghao Xuan
69674-69687

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The putative oncotarget CSN5 controls a transcriptionuncorrelated p53mediated autophagy implicated in cancer cell survival under curcumin treatment	The putative oncotarget CSN5 controls a transcriptionuncorrelated p53mediated autophagy implicated in cancer cell survival under curcumin treatment
https://doi.org/10.18632/oncotarget.11940 Qing-Yu Zhang, Rui Jin, Xian Zhang, Ji-Po Sheng, Fang Yu, Ren-Xiang Tan, Ying Pan, Jun-Jian Huang, and Ling-Dong Kong
69688-69702

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Marine compound rhizochalinin shows high in vitro and in vivo efficacy in castration resistant prostate cancer	Marine compound rhizochalinin shows high in vitro and in vivo efficacy in castration resistant prostate cancer
https://doi.org/10.18632/oncotarget.11941 Sergey A. Dyshlovoy, Katharina Otte, Winfried H. Alsdorf, Jessica Hauschild, Tobias Lange, Simone Venz, Christiane K. Bauer, Robert Bähring, Kerstin Amann, Ramin Mandanchi, Udo Schumacher, Jennifer Schröder-Schwarz, Tatyana N. Makarieva, Alla G. Guzii, Kseniya M. Tabakmakher, Sergey N. Fedorov, Larisa K. Shubina, Igor E. Kasheverov, Heimo Ehmke, Thomas Steuber, Valentin A. Stonik, Carsten Bokemeyer, Friedemann Honecker, and Gunhild von Amsberg
69703-69717

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Toxicological and efficacy assessment of posttransition metal Indium phthalocyanine for photodynamic therapy in neuroblastoma	Toxicological and efficacy assessment of posttransition metal Indium phthalocyanine for photodynamic therapy in neuroblastoma
https://doi.org/10.18632/oncotarget.11942 Monica Neagu, Carolina Constantin, Mircea Tampa, Clara Matei, Andreea Lupu, Emilia Manole, Rodica-Mariana Ion, Concettina Fenga, and Aristidis M. Tsatsakis
69718-69732

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Nestin suppression attenuates invasive potential of endometrial cancer cells by downregulating TGFβ signaling pathway	Nestin suppression attenuates invasive potential of endometrial cancer cells by downregulating TGFβ signaling pathway
https://doi.org/10.18632/oncotarget.11947 Amber A. Bokhari, Tabari M. Baker, Batsukh Dorjbal, Sana Waheed, Christopher M. Zahn, Chad A. Hamilton, G. Larry Maxwell, and Viqar Syed
69733-69748

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Programmed deathligand 1 is upregulated in intrahepatic lymphoepitheliomalike cholangiocarcinoma	Programmed deathligand 1 is upregulated in intrahepatic lymphoepitheliomalike cholangiocarcinoma
https://doi.org/10.18632/oncotarget.11949 Lei Wang, Hui Dong, Shujuan Ni, Dan Huang, Cong Tan, Bin Chang, and Weiqi Sheng
69749-69759

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Ibrutinib targets mutantEGFR kinase with a distinct binding conformation	Ibrutinib targets mutantEGFR kinase with a distinct binding conformation
https://doi.org/10.18632/oncotarget.11951 Aoli Wang, Xiao-E Yan, Hong Wu, Wenchao Wang, Chen Hu, Cheng Chen, Zheng Zhao, Peng Zhao, Xixiang Li, Li Wang, Beilei Wang, Zi Ye, Jinhua Wang, Chu Wang, Wei Zhang, Nathanael S. Gray, Ellen L. Weisberg, Liang Chen, Jing Liu, Cai-Hong Yun, and Qingsong Liu
69760-69769

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Rottlerin inhibits cell growth and invasion via downregulation of Cdc20 in glioma cells	Rottlerin inhibits cell growth and invasion via downregulation of Cdc20 in glioma cells
https://doi.org/10.18632/oncotarget.11974 Lixia Wang, Yingying Hou, Xuyuan Yin, Jingna Su, Zhe Zhao, Xiantao Ye, Xiuxia Zhou, Li Zhou, and Zhiwei Wang
69770-69782

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iOriHuman: identify human origin of replication by incorporating dinucleotide physicochemical properties into pseudo nucleotide composition	iOriHuman: identify human origin of replication by incorporating dinucleotide physicochemical properties into pseudo nucleotide composition
https://doi.org/10.18632/oncotarget.11975 Chang-Jian Zhang, Hua Tang, Wen-Chao Li, Hao Lin, Wei Chen, and Kuo-Chen Chou
69783-69793

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A simple selectionfree method for detecting disseminated tumor cells DTCs in murine bone marrow	A simple selectionfree method for detecting disseminated tumor cells DTCs in murine bone marrow
https://doi.org/10.18632/oncotarget.12000 Kenneth C. Valkenburg, Sarah R. Amend, James E. Verdone, Emma E. van der Toom, James R. Hernandez, Michael A. Gorin, and Kenneth J. Pienta
69794-69803

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Blocking downstream signaling pathways in the context of HDAC inhibition promotes apoptosis preferentially in cells harboring mutant Ras	Blocking downstream signaling pathways in the context of HDAC inhibition promotes apoptosis preferentially in cells harboring mutant Ras
https://doi.org/10.18632/oncotarget.12001 Julian C. Bahr, Robert W. Robey, Victoria Luchenko, Agnes Basseville, Arup R. Chakraborty, Hanna Kozlowski, Gary T. Pauly, Paresma Patel, Joel P. Schneider, Michael M. Gottesman, and Susan E. Bates
69804-69815

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Large variety in a panel of human colon cancer organoids in response to EZH2 inhibition	Large variety in a panel of human colon cancer organoids in response to EZH2 inhibition
https://doi.org/10.18632/oncotarget.12002 Martijn AJ Koppens, Gergana Bounova, Paulien Cornelissen-Steijger, Nienke de Vries, Owen J Sansom, Lodewyk FA Wessels, and Maarten van Lohuizen
69816-69828

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Evidence that vitronectin is a potent migrationenhancing factor for cancer cells chaperoned by fibrinogen: a novel view of the metastasis of cancer cells to lowfibrinogen lymphatics and body cavities	Evidence that vitronectin is a potent migrationenhancing factor for cancer cells chaperoned by fibrinogen: a novel view of the metastasis of cancer cells to lowfibrinogen lymphatics and body cavities
https://doi.org/10.18632/oncotarget.12003 Gabriela Schneider, Ewa Bryndza, Agata Poniewierska-Baran, Karol Serwin, Malwina Suszynska, Zachariah P. Sellers, Michael L. Merchant, Alagammai Kaliappan, Janina Ratajczak, Magda Kucia, Nichola C. Garbett, and Mariusz Z. Ratajczak
69829-69843

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Tissue and imaging biomarkers for hypoxia predict poor outcome in endometrial cancer	Tissue and imaging biomarkers for hypoxia predict poor outcome in endometrial cancer
https://doi.org/10.18632/oncotarget.12004 Anna Berg, Kristine E. Fasmer, Karen K. Mauland, Sigmund Ytre-Hauge, Erling A. Hoivik, Jenny A. Husby, Ingvild L. Tangen, Jone Trovik, Mari K. Halle, Kathrine Woie, Line Bjørge, Atle Bjørnerud, Helga B. Salvesen, Henrica M. J. Werner, Camilla Krakstad, and Ingfrid S. Haldorsen
69844-69856

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SubpathwayLNCE: Identify dysfunctional subpathways competitively regulated by lncRNAs through integrating lncRNAmRNA expression profile and pathway topologies	SubpathwayLNCE: Identify dysfunctional subpathways competitively regulated by lncRNAs through integrating lncRNAmRNA expression profile and pathway topologies
https://doi.org/10.18632/oncotarget.12005 Xinrui Shi, Yanjun Xu, Chunlong Zhang, Li Feng, Zeguo Sun, Junwei Han, Fei Su, Yunpeng Zhang, Chunquan Li, and Xia Li
69857-69870

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Cadherin6 type 2 Kcadherin CDH6 is regulated by mutant p53 in the fallopian tube but is not expressed in the ovarian surface	Cadherin6 type 2 Kcadherin CDH6 is regulated by mutant p53 in the fallopian tube but is not expressed in the ovarian surface
https://doi.org/10.18632/oncotarget.11499 Subbulakshmi Karthikeyan, Daniel D. Lantvit, Dam Hee Chae, and Joanna E. Burdette
69871-69882

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Epithelialmesenchymal transition and nuclear βcatenin induced by conditional intestinal disruption of Cdh1 with Apc is Ecadherin EC1 domain dependent	Epithelialmesenchymal transition and nuclear βcatenin induced by conditional intestinal disruption of Cdh1 with Apc is Ecadherin EC1 domain dependent
https://doi.org/10.18632/oncotarget.11513 Julia Matheson, Claudia Bühnemann, Emma J. Carter, David Barnes, Hans-Jürgen Hoppe, Jennifer Hughes, Stephen Cobbold, James Harper, Hans Morreau, Mirvat Surakhy, and Bassim A. Hassan
69883-69902

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Targeting MET and EGFR crosstalk signaling in triplenegative breast cancers	Targeting MET and EGFR crosstalk signaling in triplenegative breast cancers
https://doi.org/10.18632/oncotarget.12065 Erik S. Linklater, Elizabeth A. Tovar, Curt J. Essenburg, Lisa Turner, Zachary Madaj, Mary E. Winn, Marianne K. Melnik, Hasan Korkaya, Christiane R. Maroun, James G. Christensen, Matthew R. Steensma, Julie L. Boerner, and Carrie R. Graveel
69903-69915

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Evaluating clinical and prognostic implications of Glypican3 in hepatocellular carcinoma	Evaluating clinical and prognostic implications of Glypican3 in hepatocellular carcinoma
https://doi.org/10.18632/oncotarget.12066 Ahmed Omar Kaseb, Manal Hassan, Sahin Lacin, Reham Abdel-Wahab, Hesham M. Amin, Ahmed Shalaby, Robert A. Wolff, James Yao, Asif Rashid, Bharathi Vennapusa, Janine Feng, and Toshihiko Ohtomo
69916-69926

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SMAD4 loss enables EGF TGFβ1 and S100A8/A9 induced activation of critical pathways to invasion in human pancreatic adenocarcinoma cells	SMAD4 loss enables EGF TGFβ1 and S100A8/A9 induced activation of critical pathways to invasion in human pancreatic adenocarcinoma cells
https://doi.org/10.18632/oncotarget.12068 Stefania Moz, Daniela Basso, Dania Bozzato, Paola Galozzi, Filippo Navaglia, Ola H. Negm, Giorgio Arrigoni, Carlo-Federico Zambon, Andrea Padoan, Paddy Tighe, Ian Todd, Cinzia Franchin, Sergio Pedrazzoli, Leonardo Punzi, and Mario Plebani
69927-69944

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification of Bisindolylmaleimide IX as a potential agent to treat drugresistant BCRABL positive leukemia	Identification of Bisindolylmaleimide IX as a potential agent to treat drugresistant BCRABL positive leukemia
https://doi.org/10.18632/oncotarget.11566 Xin Zhang, Deyong Jia, Junping Ao, Huijuan Liu, Yi Zang, Mohammad Azam, Samy L. Habib, Jia Li, Xinsen Ruan, Hao Jia, Xueying Wang, and Baojie Li
69945-69960

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Preclinical investigation of ibrutinib a Bruton’s kinase tyrosine Btk inhibitor in suppressing glioma tumorigenesis and stem cell phenotypes	Preclinical investigation of ibrutinib a Bruton’s kinase tyrosine Btk inhibitor in suppressing glioma tumorigenesis and stem cell phenotypes
https://doi.org/10.18632/oncotarget.11572 Li Wei, Yu-Kai Su, Chien-Min Lin, Tsu-Yi Chao, Shang-Pen Huang, Thanh-Tuan Huynh, Hsun-Jin Jan, Jacqueline Whang-Peng, Jeng-Fong Chiou, Alexander T.H. Wu, and Michael Hsiao
69961-69975

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Fibroblast growth factor receptor 4 induced resistance to radiation therapy in colorectal cancer	Fibroblast growth factor receptor 4 induced resistance to radiation therapy in colorectal cancer
https://doi.org/10.18632/oncotarget.12099 Mohamed A. Ahmed, Edgar Selzer, Wolfgang Dörr, Gerd Jomrich, Felix Harpain, Gerd R. Silberhumer, Leonhard Müllauer, Klaus Holzmann, Bettina Grasl-Kraupp, Michael Grusch, Walter Berger, and Brigitte Marian
69976-69990

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A threegene signature for prognosis in patients with MGMT promotermethylated glioblastoma	A threegene signature for prognosis in patients with MGMT promotermethylated glioblastoma
https://doi.org/10.18632/oncotarget.11726 Wen Wang, Lu Zhang, Zheng Wang, Fan Yang, Haoyuan Wang, Tingyu Liang, Fan Wu, Qing Lan, Jiangfei Wang, and Jizong Zhao
69991-69999

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Acquired resistance to venetoclax ABT199 in t14;18 positive lymphoma cells	Acquired resistance to venetoclax ABT199 in t14;18 positive lymphoma cells
https://doi.org/10.18632/oncotarget.12132 Juraj Bodo, Xiaoxian Zhao, Lisa Durkin, Andrew J. Souers, Darren C. Phillips, Mitchell R. Smith, and Eric D. Hsi
70000-70010

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ABCB1 and ABCC11 confer resistance to eribulin in breast cancer cell lines	ABCB1 and ABCC11 confer resistance to eribulin in breast cancer cell lines
https://doi.org/10.18632/oncotarget.11727 Takaaki Oba, Hiroto Izumi, and Ken-ichi Ito
70011-70027

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Targeting Notch signaling as a novel therapy for retinoblastoma	Targeting Notch signaling as a novel therapy for retinoblastoma
https://doi.org/10.18632/oncotarget.12142 Laura Asnaghi, Arushi Tripathy, Qian Yang, Harpreet Kaur, Allison Hanaford, Wayne Yu, and Charles G. Eberhart
70028-70044

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Paraoxonase 3 inhibits cell proliferation and serves as a prognostic predictor in hepatocellular carcinoma	Paraoxonase 3 inhibits cell proliferation and serves as a prognostic predictor in hepatocellular carcinoma
https://doi.org/10.18632/oncotarget.12145 Jie Cai, Sheng-Xian Yuan, Fu Yang, Qi-Fei Tao, Yuan Yang, Qing-Guo Xu, Zhen-Guang Wang, Jian Yu, Kong-Ying Lin, Zong-Yan Wang, Jin-Zhao Ma, Chuan-Chuan Zhou, Fang Wang, Shu-Han Sun, and Wei-Ping Zhou
70045-70057

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miR204 suppresses the development and progression of human glioblastoma by targeting ATF2	miR204 suppresses the development and progression of human glioblastoma by targeting ATF2
https://doi.org/10.18632/oncotarget.11732 Shiwei Song, Abul Fajol, Xiankun Tu, Baogang Ren, and Songsheng Shi
70058-70065

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Metaanalysis comparing chewing gum versus standard postoperative care after colorectal resection	Metaanalysis comparing chewing gum versus standard postoperative care after colorectal resection
https://doi.org/10.18632/oncotarget.11735 Guo-Min Song, Yong-Hong Deng, Ying-Hui Jin, Jian-Guo Zhou, and Xu Tian
70066-70079

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

FRMD6 inhibits human glioblastoma growth and progression by negatively regulating activity of receptor tyrosine kinases	FRMD6 inhibits human glioblastoma growth and progression by negatively regulating activity of receptor tyrosine kinases
https://doi.org/10.18632/oncotarget.12148 Yin Xu, Kaiqiang Wang, and Qin Yu
70080-70091

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Gemcitabine inhibits immune escape of pancreatic cancer by down regulating the soluble ULBP2 protein	Gemcitabine inhibits immune escape of pancreatic cancer by down regulating the soluble ULBP2 protein
https://doi.org/10.18632/oncotarget.11780 Xiansheng Lin, Mei Huang, Fang Xie, Hangcheng Zhou, Ji Yang, and Qiang Huang
70092-70099

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Secondary nuclear targeting of mesoporous silica nanoparticles for cancerspecific drug delivery based on charge inversion	Secondary nuclear targeting of mesoporous silica nanoparticles for cancerspecific drug delivery based on charge inversion
https://doi.org/10.18632/oncotarget.12149 Jianwen Zhao, Fengfeng Zhao, Xiyong Wang, Xiaobo Fan, and Guoqiu Wu
70100-70112

Abstract  |  PDF  |  Full Text  |  How to cite

BRCA mutations and survival in breast cancer: an updated systematic review and metaanalysis	BRCA mutations and survival in breast cancer: an updated systematic review and metaanalysis
https://doi.org/10.18632/oncotarget.12158 Yaning Zhu, Jian Wu, Chengwan Zhang, Suan Sun, Jian Zhang, Wenjie Liu, Jian Huang, and Zhihong Zhang
70113-70127

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Efficacy of D5F3 IHC for detecting ALK gene rearrangement in NSCLC patients: a systematic review and metaanalysis	Efficacy of D5F3 IHC for detecting ALK gene rearrangement in NSCLC patients: a systematic review and metaanalysis
https://doi.org/10.18632/oncotarget.11806 Hu Ma, Wen-Xiu Yao, Lang Huang, Su-Han Jin, Da-Hai Liu, Yuan Liu, Xu Tian, Jin-Hui Tian, and Jian-Guo Zhou
70128-70142

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Interferonstimulated gene 15 induces cancer cell death by suppressing the NFκB signaling pathway	Interferonstimulated gene 15 induces cancer cell death by suppressing the NFκB signaling pathway
https://doi.org/10.18632/oncotarget.12160 Hongwu Mao, Man Wang, Biyin Cao, Haibin Zhou, Zubin Zhang, and Xinliang Mao
70143-70151

Abstract  |  PDF  |  Full Text  |  How to cite

Nodal signaling promotes vasculogenic mimicry formation in breast cancer via the Smad2/3 pathway	Nodal signaling promotes vasculogenic mimicry formation in breast cancer via the Smad2/3 pathway
https://doi.org/10.18632/oncotarget.12161 Wenchen Gong, Baocun Sun, Xiulan Zhao, Danfang Zhang, Junying Sun, Tieju Liu, Qiang Gu, Xueyi Dong, Fang Liu, Yong Wang, Xian Lin, and Yanlei Li
70152-70167

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A dose increased onceweekly bortezomibbased combination therapy for multiple myeloma	A dose increased onceweekly bortezomibbased combination therapy for multiple myeloma
https://doi.org/10.18632/oncotarget.12162 Daolin Wei, Yin Tong, Haitao Bai, Qi Cai, Yanrong Gao, and Chun Wang
70168-70174

Abstract  |  PDF  |  Full Text  |  How to cite

MMP1 promoter polymorphism is associated with risk of radiationinduced lung injury in lung cancer patients treated with radiotherapy	MMP1 promoter polymorphism is associated with risk of radiationinduced lung injury in lung cancer patients treated with radiotherapy
https://doi.org/10.18632/oncotarget.12164 Bo Liu, Minxiao Yi, Yang Tang, Qingxu Liu, Hong Qiu, Yanmei Zou, Ping Peng, Lu Zhang, Chunping Hu, and Xianglin Yuan
70175-70184

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A metaanalysis of weekly cisplatin versus three weekly cisplatin chemotherapy plus concurrent radiotherapy CRT for advanced head and neck cancer HNC	A metaanalysis of weekly cisplatin versus three weekly cisplatin chemotherapy plus concurrent radiotherapy CRT for advanced head and neck cancer HNC
https://doi.org/10.18632/oncotarget.11824 Jian Guan, Yue Zhang, Qinyang Li, Yaowei Zhang, Lu Li, Min Chen, Nanjie Xiao, and Longhua Chen
70185-70193

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MicroRNA552 enhances metastatic capacity of colorectal cancer cells by targeting a disintegrin and metalloprotease 28	MicroRNA552 enhances metastatic capacity of colorectal cancer cells by targeting a disintegrin and metalloprotease 28
https://doi.org/10.18632/oncotarget.12169 Jian Wang, Hai Li, Yong Wang, Libin Wang, Xiurui Yan, Dong Zhang, Xiaoqiang Ma, Yong Du, Xiaoming Liu, and Yinxue Yang
70194-70210

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

SPARC expression in gastric cancer predicts poor prognosis: Results from a clinical cohort pooled analysis and GSEA assay	SPARC expression in gastric cancer predicts poor prognosis: Results from a clinical cohort pooled analysis and GSEA assay
https://doi.org/10.18632/oncotarget.12191 Zhi Li, Ao-Di Li, Lu Xu, De-Wei Bai, Ke-Zuo Hou, Hua-Chuan Zheng, Xiu-Juan Qu, and Yun-Peng Liu
70211-70222

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

CpGinduced antitumor immunity requires IL12 in expansion of effector cells and downregulation of PD1	CpGinduced antitumor immunity requires IL12 in expansion of effector cells and downregulation of PD1
https://doi.org/10.18632/oncotarget.11833 Peng Yin, Xin Liu, Aaron S. Mansfield, Susan M. Harrington, Yinghua Li, Yiyi Yan, and Haidong Dong
70223-70231

Abstract  |  PDF  |  Full Text  |  How to cite

Endothelin1 promotes epithelial–mesenchymal transition in human chondrosarcoma cells by repressing miR300	Endothelin1 promotes epithelial–mesenchymal transition in human chondrosarcoma cells by repressing miR300
https://doi.org/10.18632/oncotarget.11835 Min-Huan Wu, Pei-Han Huang, Mingli Hsieh, Chun-Hao Tsai, Hsien-Te Chen, and Chih-Hsin Tang
70232-70246

Abstract  |  PDF  |  Full Text  |  How to cite

IL24 modulates the high mobility group HMG A1/miR222 /AKT signaling in lung cancer cells	IL24 modulates the high mobility group HMG A1/miR222 /AKT signaling in lung cancer cells
https://doi.org/10.18632/oncotarget.11838 Janani Panneerselvam, Akhil Srivastava, Ranganayaki Muralidharan, Qi Wang, Wei Zheng, Lichao Zhao, Alshine Chen, Yan D. Zhao, Anupama Munshi, and Rajagopal Ramesh
70247-70263

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Preexisting mutations related to tenofovir in chronic hepatitis B patients with longterm nucleostide analogue drugs treatment by ultradeep pyrosequencing	Preexisting mutations related to tenofovir in chronic hepatitis B patients with longterm nucleostide analogue drugs treatment by ultradeep pyrosequencing
https://doi.org/10.18632/oncotarget.11840 Xiaxia Zhang, Minran Li, Hongli Xi, Renwen Zhang, Jianhong Chen, Yu Zhang, and Xiaoyuan Xu
70264-70275

Abstract  |  PDF  |  Full Text  |  How to cite

Polyphyllin G induce apoptosis and autophagy in human nasopharyngeal cancer cells by modulation of AKT and mitogenactivated protein kinase pathways in vitro and in vivo	Polyphyllin G induce apoptosis and autophagy in human nasopharyngeal cancer cells by modulation of AKT and mitogenactivated protein kinase pathways in vitro and in vivo
https://doi.org/10.18632/oncotarget.11839 Jui-Chieh Chen, Ming-Ju Hsieh, Chih-Jung Chen, Jen-Tsun Lin, Yu-Sheng Lo, Yi-Ching Chuang, Su-Yu Chien, and Mu-Kuan Chen
70276-70289

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The clock gene PER1 plays an important role in regulating the clock gene network in human oral squamous cell carcinoma cells	The clock gene PER1 plays an important role in regulating the clock gene network in human oral squamous cell carcinoma cells
https://doi.org/10.18632/oncotarget.11844 Qin Zhao, Gang Zheng, Kai Yang, Yi-ran Ao, Xiao-li Su, Yu Li, and Xiao-qiang Lv
70290-70302

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

NTS/NTR1 coexpression enhances epithelialtomesenchymal transition and promotes tumor metastasis by activating the Wnt/βcatenin signaling pathway in hepatocellular carcinoma	NTS/NTR1 coexpression enhances epithelialtomesenchymal transition and promotes tumor metastasis by activating the Wnt/βcatenin signaling pathway in hepatocellular carcinoma
https://doi.org/10.18632/oncotarget.11854 Yingnan Ye, Xinxin Long, Lijie Zhang, Jieying Chen, Pengpeng Liu, Hui Li, Feng Wei, Wenwen Yu, Xiubao Ren, and Jinpu Yu
70303-70322

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ATAD2 is an epigenetic reader of newly synthesized histone marks during DNA replication	ATAD2 is an epigenetic reader of newly synthesized histone marks during DNA replication
https://doi.org/10.18632/oncotarget.11855 Seong Joo Koo, Amaury E. Fernández-Montalván, Volker Badock, Christopher J. Ott, Simon J. Holton, Oliver von Ahsen, Joern Toedling, Sarah Vittori, James E. Bradner, and Mátyás Gorjánácz
70323-70335

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Oncogenic activation of FAK drives apoptosis suppression in a 3Dculture model of breast cancer initiation	Oncogenic activation of FAK drives apoptosis suppression in a 3Dculture model of breast cancer initiation
https://doi.org/10.18632/oncotarget.11856 Scott Walker, Fiona Foster, Amber Wood, Thomas Owens, Keith Brennan, Charles H. Streuli, and Andrew P. Gilmore
70336-70352

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Pathologic heterogeneity of lung adenocarcinomas: A novel pathologic index predicts survival	Pathologic heterogeneity of lung adenocarcinomas: A novel pathologic index predicts survival
https://doi.org/10.18632/oncotarget.11857 Geewon Lee, E-Ryung Choi, Ho Yun Lee, Ji Yun Jeong, Joong Hyun Ahn, Seonwoo Kim, Jungmin Bae, Hong Kwan Kim, Yong Soo Choi, Jhingook Kim, Jaeil Zo, Kyung Soo Lee, and Young Mog Shim
70353-70363

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Induction of epithelialmesenchymal transition EMT by Beclin 1 knockdown via posttranscriptional upregulation of ZEB1 in thyroid cancer cells	Induction of epithelialmesenchymal transition EMT by Beclin 1 knockdown via posttranscriptional upregulation of ZEB1 in thyroid cancer cells
https://doi.org/10.18632/oncotarget.12217 Si Li, Hai-Yan Zhang, Zhen-Xian Du, Chao Li, Ming-Xin An, Zhi-Hong Zong, Bao-Qin Liu, and Hua-Qin Wang
70364-70377

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Dickkopf1 expression is associated with tumorigenity and lymphatic metastasis in human hilar cholangiocarcinoma	Dickkopf1 expression is associated with tumorigenity and lymphatic metastasis in human hilar cholangiocarcinoma
https://doi.org/10.18632/oncotarget.11859 Xiang-de Shi, Xian-huan Yu, Wen-rui Wu, Xiao-lin Xu, Jie-Yu Wang, Lei-bo Xu, Rui Zhang, and Chao Liu
70378-70387

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Novel tumor suppressor microRNA at frequently deleted chromosomal region 8p21 regulates Epidermal Growth Factor Receptor in prostate cancer	Novel tumor suppressor microRNA at frequently deleted chromosomal region 8p21 regulates Epidermal Growth Factor Receptor in prostate cancer
https://doi.org/10.18632/oncotarget.11865 Nathan Bucay, Kirandeep Sekhon, Shahana Majid, Soichiro Yamamura, Varahram Shahryari, Z. Laura Tabatabai, Kirsten Greene, Yuichiro Tanaka, Rajvir Dahiya, Guoren Deng, and Sharanjot Saini
70388-70403

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Androgen receptor differentially regulates the proliferation of prostatic epithelial cells in vitro and in vivo	Androgen receptor differentially regulates the proliferation of prostatic epithelial cells in vitro and in vivo
https://doi.org/10.18632/oncotarget.11879 Shu Yang, Ming Jiang, Magdalena M. Grabowska, Jiahe Li, Zachary M. Connelly, Jianghong Zhang, Simon W. Hayward, Justin M. Cates, Guichun Han, and Xiuping Yu
70404-70419

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Loss of ZNF32 augments the regeneration of nervous lateral line system through negative regulation of SOX2 transcription	Loss of ZNF32 augments the regeneration of nervous lateral line system through negative regulation of SOX2 transcription
https://doi.org/10.18632/oncotarget.11895 Yuyan Wei, Kai Li, Shaohua Yao, Junping Gao, Jun Li, Yanna Shang, Jie Zhang, Le Zhang, Yanyan Li, Xianming Mo, Wentong Meng, Rong Xiang, Jiankun Hu, Ping Lin, and Yuquan Wei
70420-70436

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Zanthoxylum fruit extract from Japanese pepper promotes autophagic cell death in cancer cells	Zanthoxylum fruit extract from Japanese pepper promotes autophagic cell death in cancer cells
https://doi.org/10.18632/oncotarget.11926 Reo Nozaki, Toru Kono, Hiroki Bochimoto, Tsuyoshi Watanabe, Kaori Oketani, Yuichi Sakamaki, Naoto Okubo, Koji Nakagawa, and Hiroshi Takeda
70437-70446

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A vicious cycle between acid sensing and survival signaling in myeloma cells: acidinduced epigenetic alteration	A vicious cycle between acid sensing and survival signaling in myeloma cells: acidinduced epigenetic alteration
https://doi.org/10.18632/oncotarget.11927 Ryota Amachi, Masahiro Hiasa, Jumpei Teramachi, Takeshi Harada, Asuka Oda, Shingen Nakamura, Derek Hanson, Keiichiro Watanabe, Shiro Fujii, Hirokazu Miki, Kumiko Kagawa, Masami Iwasa, Itsuro Endo, Takeshi Kondo, Sumiko Yoshida, Ken-ichi Aihara, Kiyoe Kurahashi, Yoshiaki Kuroda, Hideaki Horikawa, Eiji Tanaka, Toshio Matsumoto, and Masahiro Abe
70447-70461

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A microRNA/Runx1/Runx2 network regulates prostate tumor progression from onset to adenocarcinoma in TRAMP mice	A microRNA/Runx1/Runx2 network regulates prostate tumor progression from onset to adenocarcinoma in TRAMP mice
https://doi.org/10.18632/oncotarget.11992 Nicholas H. Farina, Areg Zingiryan, Jacqueline A. Akech, Cody J. Callahan, Huimin Lu, Janet L. Stein, Lucia R. Languino, Gary S. Stein, and Jane B. Lian
70462-70474

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

RTEL1 polymorphisms are associated with lung cancer risk in the Chinese Han population	RTEL1 polymorphisms are associated with lung cancer risk in the Chinese Han population
https://doi.org/10.18632/oncotarget.12297 Shouchun Yan, Ridong Xia, Tianbo Jin, Hui Ren, Hua Yang, Jing Li, Mengdan Yan, Yuanyuan Zhu, and Mingwei Chen
70475-70480

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Identification of the APC/C cofactor FZR1 as a novel therapeutic target for multiple myeloma	Identification of the APC/C cofactor FZR1 as a novel therapeutic target for multiple myeloma
https://doi.org/10.18632/oncotarget.12026 Lisa J. Crawford, Gordon Anderson, Cliona K. Johnston, and Alexandra E. Irvine
70481-70493

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

COL3A1 and SNAP91: novel glioblastoma markers with diagnostic and prognostic value	COL3A1 and SNAP91: novel glioblastoma markers with diagnostic and prognostic value
https://doi.org/10.18632/oncotarget.12038 Yuan-Feng Gao, Xiao-Yuan Mao, Tao Zhu, Chen-Xue Mao, Zhi-Xiong Liu, Zhi-Bin Wang, Ling Li, Xi Li, Ji-Ye Yin, Wei Zhang, Hong-Hao Zhou, and Zhao-Qian Liu
70494-70503

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Shikonin potentiates the effect of arsenic trioxide against human hepatocellular carcinoma in vitro and in vivo	Shikonin potentiates the effect of arsenic trioxide against human hepatocellular carcinoma in vitro and in vivo
https://doi.org/10.18632/oncotarget.12041 Jingjing Song, Zhongwei Zhao, Xiaoxi Fan, Minjiang Chen, Xingyao Cheng, Dengke Zhang, Fazong Wu, Xihui Ying, and Jiansong Ji
70504-70515

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Analysis of the variability among radiation oncologists in delineation of the postsurgical tumor bed based on 4DCT	Analysis of the variability among radiation oncologists in delineation of the postsurgical tumor bed based on 4DCT
https://doi.org/10.18632/oncotarget.12044 Wei Wang, Jianbin Li, Jun Xing, Min Xu, Qian Shao, Tingyong Fan, Bing Guo, and Shanshan Liu
70516-70523

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Primary and recurrent ovarian highgrade serous carcinomas display similar microRNA expression patterns relative to those of normal ovarian tissue	Primary and recurrent ovarian highgrade serous carcinomas display similar microRNA expression patterns relative to those of normal ovarian tissue
https://doi.org/10.18632/oncotarget.12045 Eun Ji Nam, Sunghoon Kim, Taek Sang Lee, Hee Jung Kim, Jung Yun Lee, Sang Wun Kim, Jae Hoon Kim, and Young Tae Kim
70524-70534

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinical benefit from EGFRTKI plus ginsenoside Rg3 in patients with advanced nonsmall cell lung cancer harboring EGFR active mutation	Clinical benefit from EGFRTKI plus ginsenoside Rg3 in patients with advanced nonsmall cell lung cancer harboring EGFR active mutation
https://doi.org/10.18632/oncotarget.12059 Yan Li, Yanmei Wang, Kai Niu, Xiewan Chen, Liqin Xia, Dingxi Lu, Rui Kong, Zhengtang Chen, Yuzhong Duan, and Jianguo Sun
70535-70545

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Deptor transcriptionally regulates endoplasmic reticulum homeostasis in multiple myeloma cells	Deptor transcriptionally regulates endoplasmic reticulum homeostasis in multiple myeloma cells
https://doi.org/10.18632/oncotarget.12060 Valeria Catena, Tiziana Bruno, Francesca De Nicola, Frauke Goeman, Matteo Pallocca, Simona Iezzi, Cristina Sorino, Giovanni Cigliana, Aristide Floridi, Giovanni Blandino, and Maurizio Fanciulli
70546-70558

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Hepatitis B virus X induces inflammation and cancer in mice liver through dysregulation of cytoskeletal remodeling and lipid metabolism	Hepatitis B virus X induces inflammation and cancer in mice liver through dysregulation of cytoskeletal remodeling and lipid metabolism
https://doi.org/10.18632/oncotarget.12372 Zhongwei Xu, Linghui Zhai, Tailong Yi, Huiying Gao, Fengxu Fan, Yanchang Li, Youliang Wang, Ning Li, Xiaohua Xing, Na Su, Feilin Wu, Lei Chang, Xiuli Chen, Erhei Dai, Chao Zhao, Xiao Yang, Chunping Cui, and Ping Xu
70559-70574

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

TWIST1/miR584/TUSC2 pathway induces resistance to apoptosis in thyroid cancer cells	TWIST1/miR584/TUSC2 pathway induces resistance to apoptosis in thyroid cancer cells
https://doi.org/10.18632/oncotarget.12129 Francesca Maria Orlandella, Gennaro Di Maro, Clara Ugolini, Fulvio Basolo, and Giuliana Salvatore
70575-70588

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis	RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis
https://doi.org/10.18632/oncotarget.12130 Catherine E. Bond, Diane M. McKeone, Murugan Kalimutho, Mark L. Bettington, Sally-Ann Pearson, Troy D. Dumenil, Leesa F. Wockner, Matthew Burge, Barbara A. Leggett, and Vicki L.J. Whitehall
70589-70600

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Relationship between tumour PTEN/Akt/COX2 expression inflammatory response and survival in patients with colorectal cancer	Relationship between tumour PTEN/Akt/COX2 expression inflammatory response and survival in patients with colorectal cancer
https://doi.org/10.18632/oncotarget.12134 Antonia K. Roseweir, Arfon GMT Powell, Lindsay Bennett, Hester C. Van Wyk, James Park, Donald C. McMillan, Paul G. Horgan, and Joanne Edwards
70601-70612

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miR135b expression downregulates Ppm1e to activate AMPK signaling and protect osteoblastic cells from dexamethasone	miR135b expression downregulates Ppm1e to activate AMPK signaling and protect osteoblastic cells from dexamethasone
https://doi.org/10.18632/oncotarget.12138 Jian-Bo Fan, Jian-Wei Ruan, Wei Liu, Lun-Qing Zhu, Xin-Hui Zhu, Hong Yi, Sheng-Yu Cui, Jian-Ning Zhao, and Zhi-Ming Cui
70613-70622

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Ibrutinib synergizes with MDM2 inhibitors in promoting cytotoxicity in B chronic lymphocytic leukemia	Ibrutinib synergizes with MDM2 inhibitors in promoting cytotoxicity in B chronic lymphocytic leukemia
https://doi.org/10.18632/oncotarget.12139 Rebecca Voltan, Erika Rimondi, Elisabetta Melloni, Gian Matteo Rigolin, Fabio Casciano, Maria Vittoria Arcidiacono, Claudio Celeghini, Antonio Cuneo, Giorgio Zauli, and Paola Secchiero
70623-70638

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Characterization of acetate transport in colorectal cancer cells and potential therapeutic implications	Characterization of acetate transport in colorectal cancer cells and potential therapeutic implications
https://doi.org/10.18632/oncotarget.12156 Suellen Ferro, João Azevedo-Silva, Margarida Casal, Manuela Côrte-Real, Fatima Baltazar, and Ana Preto
70639-70653

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Apolipoprotein A1: a novel serum biomarker for predicting the prognosis of hepatocellular carcinoma after curative resection	Apolipoprotein A1: a novel serum biomarker for predicting the prognosis of hepatocellular carcinoma after curative resection
https://doi.org/10.18632/oncotarget.12203 Xiao-Lu Ma, Xing-Hui Gao, Zi-Jun Gong, Jiong Wu, Lu Tian, Chun-Yan Zhang, Yan Zhou, Yun-Fan Sun, Bo Hu, Shuang-jian Qiu, Jian Zhou, Jia Fan, Wei Guo, and Xin-Rong Yang
70654-70668

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Human PDE4D isoform composition is deregulated in primary prostate cancer and indicative for disease progression and development of distant metastases	Human PDE4D isoform composition is deregulated in primary prostate cancer and indicative for disease progression and development of distant metastases
https://doi.org/10.18632/oncotarget.12204 René Böttcher, Kalyan Dulla, Dianne van Strijp, Natasja Dits, Esther I. Verhoef, George S. Baillie, Geert J.L.H. van Leenders, Miles D. Houslay, Guido Jenster, and Ralf Hoffmann
70669-70684

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Pseudoexons provide a mechanism for allelespecific expression of APC in familial adenomatous polyposis	Pseudoexons provide a mechanism for allelespecific expression of APC in familial adenomatous polyposis
https://doi.org/10.18632/oncotarget.12206 Taina T. Nieminen, Walter Pavicic, Noora Porkka, Matti Kankainen, Heikki J. Järvinen, Anna Lepistö, and Päivi Peltomäki
70685-70698

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miR135a promotes gastric cancer progression and resistance to oxaliplatin	miR135a promotes gastric cancer progression and resistance to oxaliplatin
https://doi.org/10.18632/oncotarget.12208 Lin-Hai Yan, Zhi-Ning Chen, Li -Li, Jia Chen, Wen-E Wei, Xian-Wei Mo, Yu-Zhou Qin, Yuan Lin, and Jian-Si Chen
70699-70714

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Glutathionemediated antioxidant response and aerobic metabolism: two crucial factors involved in determining the multidrug resistance of highrisk neuroblastoma	Glutathionemediated antioxidant response and aerobic metabolism: two crucial factors involved in determining the multidrug resistance of highrisk neuroblastoma
https://doi.org/10.18632/oncotarget.12209 Renata Colla, Alberto Izzotti, Chiara De Ciucis, Daniela Fenoglio, Silvia Ravera, Andrea Speciale, Roberta Ricciarelli, Anna Lisa Furfaro, Alessandra Pulliero, Mario Passalacqua, Nicola Traverso, Maria Adelaide Pronzato, Cinzia Domenicotti, and Barbara Marengo
70715-70737

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ESM1 mediates NGFRinduced invasion and metastasis in murine oral squamous cell carcinoma	ESM1 mediates NGFRinduced invasion and metastasis in murine oral squamous cell carcinoma
https://doi.org/10.18632/oncotarget.12210 Chen Chen, June Ho Shin, Joshua T. Eggold, Man Ki Chung, Luhua H. Zhang, Jeremy Lee, and John B. Sunwoo
70738-70749

Abstract  |  PDF  |  Full Text  |  How to cite

Silencing of Profilin1 suppresses cell adhesion and tumor growth via predicted alterations in integrin and Ca2+ signaling in T24Mbased bladder cancer models	Silencing of Profilin1 suppresses cell adhesion and tumor growth via predicted alterations in integrin and Ca2+ signaling in T24Mbased bladder cancer models
https://doi.org/10.18632/oncotarget.12218 Maria Frantzi, Zoi Klimou, Manousos Makridakis, Jerome Zoidakis, Agnieszka Latosinska, Daniel M. Borràs, Bart Janssen, Ioanna Giannopoulou, Vasiliki Lygirou, Andreas C. Lazaris, Nicholas P. Anagnou, Harald Mischak, Maria G. Roubelakis, and Antonia Vlahou
70750-70768

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Long noncoding RNAs LOC285194 RP11462C241 and Nbla12061 in serum provide a new approach for distinguishing patients with colorectal cancer from healthy controls	Long noncoding RNAs LOC285194 RP11462C241 and Nbla12061 in serum provide a new approach for distinguishing patients with colorectal cancer from healthy controls
https://doi.org/10.18632/oncotarget.12220 Chuanxi Wang, Jinyu Yu, Yuping Han, Leping Li, Jie Li, Tao Li, and Peng Qi
70769-70778

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Different growth and metastatic phenotypes associated with a cellintrinsic change of Met in metastatic melanoma	Different growth and metastatic phenotypes associated with a cellintrinsic change of Met in metastatic melanoma
https://doi.org/10.18632/oncotarget.12221 Eri Adachi, Katsuya Sakai, Takumi Nishiuchi, Ryu Imamura, Hiroki Sato, and Kunio Matsumoto
70779-70793

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Randomized placebocontrolled trial evaluating the safety of oneyear administration of green tea catechins	Randomized placebocontrolled trial evaluating the safety of oneyear administration of green tea catechins
https://doi.org/10.18632/oncotarget.12222 Nagi B. Kumar, Julio Pow-Sang, Philippe E. Spiess, Jong Park, Raoul Salup, Christopher R. Williams, Howard Parnes, and Michael J. Schell
70794-70802

Abstract  |  PDF  |  Full Text  |  How to cite

The changing 50% inhibitory concentration IC50 of cisplatin: a pilot study on the artifacts of the MTT assay and the precise measurement of densitydependent chemoresistance in ovarian cancer	The changing 50% inhibitory concentration IC50 of cisplatin: a pilot study on the artifacts of the MTT assay and the precise measurement of densitydependent chemoresistance in ovarian cancer
https://doi.org/10.18632/oncotarget.12223 Yifeng He, Qiujing Zhu, Mo Chen, Qihong Huang, Wenjing Wang, Qing Li, Yuting Huang, and Wen Di
70803-70821

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Development of a selected reaction monitoring mass spectrometrybased assay to detect asparaginyl endopeptidase activity in biological fluids	Development of a selected reaction monitoring mass spectrometrybased assay to detect asparaginyl endopeptidase activity in biological fluids
https://doi.org/10.18632/oncotarget.12224 Anindita Dutta, David N. Potier, Michael J. Walker, Oliver J. Gray, Catriona Parker, Mark Holland, Andrew J.K. Williamson, Andrew Pierce, Richard D. Unwin, Shekhar Krishnan, Vaskar Saha, and Anthony D. Whetton
70822-70831

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Reduced argininosuccinate synthetase expression in refractory sarcomas: Impacts on therapeutic potential and drug resistance	Reduced argininosuccinate synthetase expression in refractory sarcomas: Impacts on therapeutic potential and drug resistance
https://doi.org/10.18632/oncotarget.12225 Youngji Kim, Eisuke Kobayashi, Daisuke Kubota, Yoshiyuki Suehara, Kenta Mukaihara, Keisuke Akaike, Ayumu Ito, Kazuo Kaneko, Hirokazu Chuman, Akira Kawai, and Shigehisa Kitano
70832-70844

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Hydroxychloroquine potentiates carfilzomib toxicity towards myeloma cells	Hydroxychloroquine potentiates carfilzomib toxicity towards myeloma cells
https://doi.org/10.18632/oncotarget.12226 Katarzyna Baranowska, Kristine Misund, Kristian K. Starheim, Toril Holien, Ida Johansson, Sagar Darvekar, Glenn Buene, Anders Waage, Geir Bjørkøy, and Anders Sundan
70845-70856

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiRNA145 increases therapeutic sensibility to gemcitabine treatment of pancreatic adenocarcinoma cells	MiRNA145 increases therapeutic sensibility to gemcitabine treatment of pancreatic adenocarcinoma cells
https://doi.org/10.18632/oncotarget.12268 Yong Lin, Xin Ge, Yiyang Wen, Zhu-Mei Shi, Qiu-Dan Chen, Min Wang, Ling-Zhi Liu, Bing-Hua Jiang, and Yuan Lu
70857-70868

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Zoledronic acid is an effective radiosensitizer in the treatment of osteosarcoma	Zoledronic acid is an effective radiosensitizer in the treatment of osteosarcoma
https://doi.org/10.18632/oncotarget.12281 Eun Ho Kim, Mi-Sook Kim, Kyung-Hee Lee, Jae-Soo Koh, Won-Gyun Jung, and Chang-Bae Kong
70869-70880

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PAK4 suppresses PDZRhoGEF activity to drive invadopodia maturation in melanoma cells	PAK4 suppresses PDZRhoGEF activity to drive invadopodia maturation in melanoma cells
https://doi.org/10.18632/oncotarget.12282 Nicole S. Nicholas, Aikaterini Pipili, Michaela S. Lesjak, Simon M. Ameer-Beg, Jenny L. C. Geh, Ciaran Healy, Alistair D. MacKenzie Ross, Maddy Parsons, Frank O. Nestle, Katie E. Lacy, and Claire M. Wells
70881-70897

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Gproteincoupled receptor 81 promotes a malignant phenotype in breast cancer through angiogenic factor secretion	Gproteincoupled receptor 81 promotes a malignant phenotype in breast cancer through angiogenic factor secretion
https://doi.org/10.18632/oncotarget.12286 Yu Jin Lee, Kyeong Jin Shin, Soo-Ah Park, Kyeong Su Park, Seorim Park, Kyun Heo, Young-Kyo Seo, Dong-Young Noh, Sung Ho Ryu, and Pann-Ghill Suh
70898-70911

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

NKp44 and NKp30 splice variant profiles in decidua and tumor tissues: a comparative viewpoint	NKp44 and NKp30 splice variant profiles in decidua and tumor tissues: a comparative viewpoint
https://doi.org/10.18632/oncotarget.12292 Avishai Shemesh, Aleksandra Kugel, Naama Steiner, Michal Yezersky, Dan Tirosh, Avishay Edri, Omri Teltsh, Benyamin Rosental, Eyal Sheiner, Eitan Rubin, Kerry S. Campbell, and Angel Porgador
70912-70923

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

DACT2 silencing by promoter CpG methylation disrupts its regulation of epithelialtomesenchymal transition and cytoskeleton reorganization in breast cancer cells	DACT2 silencing by promoter CpG methylation disrupts its regulation of epithelialtomesenchymal transition and cytoskeleton reorganization in breast cancer cells
https://doi.org/10.18632/oncotarget.12341 Tingxiu Xiang, Yichao Fan, Chunhong Li, Lili Li, Ying Ying, Junhao Mu, Weiyan Peng, Yixiao Feng, Michael Oberst, Kathleen Kelly, Guosheng Ren, and Qian Tao
70924-70935

Abstract  |  PDF  |  Full Text  |  How to cite

Smokingassociated lung cancer prevention by blockade of the betaadrenergic receptormediated insulinlike growth factor receptor activation	Smokingassociated lung cancer prevention by blockade of the betaadrenergic receptormediated insulinlike growth factor receptor activation
https://doi.org/10.18632/oncotarget.12342 Hye-Young Min, Hye-Jin Boo, Ho Jin Lee, Hyun-Ji Jang, Hye Jeong Yun, Su Jung Hwang, John Kendal Smith, Hyo-Jong Lee, and Ho-Young Lee
70936-70947

Abstract  |  PDF  |  Full Text  |  How to cite

Clinical Research Papers

Blood baseline neutrophil count predicts bevacizumab efficacy in glioblastoma	Blood baseline neutrophil count predicts bevacizumab efficacy in glioblastoma
https://doi.org/10.18632/oncotarget.10898 Aurélie Bertaut, Caroline Truntzer, Rachid Madkouri, Coureche Guillaume Kaderbhai, Valentin Derangère, Julie Vincent, Bruno Chauffert, Marie Hélene Aubriot-Lorton, Wahlid Farah, Klaus Luc Mourier, Romain Boidot, and Francois Ghiringhelli
70948-70958

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Bone marrow involvement identifies a subgroup of advanced Ewing sarcoma patients with fatal outcome irrespective of therapy in contrast to curable patients with multiple bone metastases but unaffected marrow	Bone marrow involvement identifies a subgroup of advanced Ewing sarcoma patients with fatal outcome irrespective of therapy in contrast to curable patients with multiple bone metastases but unaffected marrow
https://doi.org/10.18632/oncotarget.10938 Uwe Thiel, Angela Wawer, Irene von Luettichau, Hans-Ulrich Bender, Franziska Blaeschke, Thomas G.P. Grunewald, Marc Steinborn, Barbara Röper, Halvard Bonig, Thomas Klingebiel, Peter Bader, Ewa Koscielniak, Michael Paulussen, Uta Dirksen, Heribert Juergens, Hans-Jochem Kolb, and Stefan E.G. Burdach
70959-70968

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Concurrent paclitaxel/cisplatin chemoradiotherapy with or without consolidation chemotherapy in highrisk earlystage cervical cancer patients following radical hysterectomy: preliminary results of a phase III randomized study	Concurrent paclitaxel/cisplatin chemoradiotherapy with or without consolidation chemotherapy in highrisk earlystage cervical cancer patients following radical hysterectomy: preliminary results of a phase III randomized study
https://doi.org/10.18632/oncotarget.10450 Hongqin Zhao, Lili Li, Huafang Su, Baochai Lin, Xuebang Zhang, Shengliu Xue, Zhenghua Fei, Lihao Zhao, Qintuo Pan, Xiance Jin, and Congying Xie
70969-70978

Abstract  |  PDF  |  Full Text  |  How to cite

Twodimensional versus threedimensional laparoscopy in surgical efficacy: a systematic review and metaanalysis	Twodimensional versus threedimensional laparoscopy in surgical efficacy: a systematic review and metaanalysis
https://doi.org/10.18632/oncotarget.10916 Ji Cheng, Jinbo Gao, Xiaoming Shuai, Guobin Wang, and Kaixiong Tao
70979-70990

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Hormone receptor status may impact the survival benefit of surgery in stage IV breast cancer: a populationbased study	Hormone receptor status may impact the survival benefit of surgery in stage IV breast cancer: a populationbased study
https://doi.org/10.18632/oncotarget.11235 Yinuo Tan, Xiaofen Li, Haiyan Chen, Yeting Hu, Mengjie Jiang, Jianfei Fu, Ying Yuan, and Kefeng Ding
70991-71000

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Reviews

TH9 cell differentiation transcriptional control and function in inflammation autoimmune diseases and cancer	TH9 cell differentiation transcriptional control and function in inflammation autoimmune diseases and cancer
https://doi.org/10.18632/oncotarget.11681 Yan Li, Qing Yu, Zhengguo Zhang, Jian Wang, Simin Li, Jiangyuan Zhang, and Guangwei Liu
71001-71012

Abstract  |  PDF  |  Full Text  |  How to cite

Cellfree DNA and nextgeneration sequencing in the service of personalized medicine for lung cancer	Cellfree DNA and nextgeneration sequencing in the service of personalized medicine for lung cancer
https://doi.org/10.18632/oncotarget.11717 Catherine W. Bennett, Guy Berchem, Yeoun Jin Kim, and Victoria El-Khoury
71013-71035

Abstract  |  PDF  |  Full Text  |  How to cite

Combination treatment including targeted therapy for advanced hepatocellular carcinoma	Combination treatment including targeted therapy for advanced hepatocellular carcinoma
https://doi.org/10.18632/oncotarget.11954 Jianzhen Lin, Liangcai Wu, Xue Bai, Yuan Xie, Anqiang Wang, Haohai Zhang, Xiaobo Yang, Xueshuai Wan, Xin Lu, Xinting Sang, and Haitao Zhao
71036-71051

Abstract  |  PDF  |  Full Text  |  How to cite

Review: Traumatic brain injury and hyperglycemia a potentially modifiable risk factor	Review: Traumatic brain injury and hyperglycemia a potentially modifiable risk factor
https://doi.org/10.18632/oncotarget.11958 Jia Shi, Bo Dong, Yumin Mao, Wei Guan, Jiachao Cao, Rongxing Zhu, and Suinuan Wang
71052-71061

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