VOLUME 7 (2016)
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Disruption of KIF3A in patient-derived glioblastoma cells: effects on ciliogenesis, hedgehog sensitivity, and tumorigenesis. See Hoang-Minh et al.
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Table of Contents
Priority Research Papers
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| Germline polymorphisms in an enhancer of PSIP1 are associated with progressionfree survival in epithelial ovarian cancer |
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https://doi.org/10.18632/oncotarget.7047
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| 6353-6368 |
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| CEST theranostics: labelfree MR imaging of anticancer drugs |
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https://doi.org/10.18632/oncotarget.7141
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| 6369-6378 |
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| PRDX2 and PRDX4 are negative regulators of hypoxiainducible factors under conditions of prolonged hypoxia |
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https://doi.org/10.18632/oncotarget.7142
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| 6379-6397 |
Research Papers: Gerotarget (Focus on Aging)
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| The effects of aging and maternal protein restriction during lactation on thymic involution and peripheral immunosenescence in adult mice |
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https://doi.org/10.18632/oncotarget.7176
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| 6398-6409 |
Research Papers: Pathology
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| Extracorporeal Shock Wave Treatment ESWT enhances the in vitroinduced differentiation of human tendonderived stem/progenitor cells hTSPCs |
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https://doi.org/10.18632/oncotarget.7064
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| 6410-6423 |
Research Papers: Immunology
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| Residual tumor microfoci and overwhelming regulatory T lymphocyte infiltration are the causes of bladder cancer recurrence |
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https://doi.org/10.18632/oncotarget.7024
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| 6424-6435 |
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| Upregulation of immunomodulatory effects of mouse bonemarrow derived mesenchymal stem cells by tetrahydrocannabinol pretreatment involving cannabinoid receptor CB2 |
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https://doi.org/10.18632/oncotarget.7042
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| 6436-6447 |
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| Human melanoma immunotherapy using tumor antigenspecific T cells generated in humanized mice |
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https://doi.org/10.18632/oncotarget.7044
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| 6448-6459 |
Research Papers: Chromosome
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| Hierarchical regulation of the genome: global changes in nucleosome organization potentiate genome response |
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https://doi.org/10.18632/oncotarget.6841
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| 6460-6475 |
Reviews
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| MicroRNAs as growth regulators their function and biomarker status in colorectal cancer |
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https://doi.org/10.18632/oncotarget.6390
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| 6476-6505 |
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| Understanding the role of the kynurenine pathway in human breast cancer immunobiology |
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https://doi.org/10.18632/oncotarget.6467
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| 6506-6520 |
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| Novel strategies to target the ubiquitin proteasome system in multiple myeloma |
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https://doi.org/10.18632/oncotarget.6658
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| 6521-6537 |
Research Papers
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| Integrated genomic analyses identify frequent gene fusion events and VHL inactivation in gastrointestinal stromal tumors |
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https://doi.org/10.18632/oncotarget.3731
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| 6538-6551 |
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| RUNX1 and FOXP3 interplay regulates expression of breast cancer related genes |
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https://doi.org/10.18632/oncotarget.6771
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| 6552-6565 |
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| SLC7A5 act as a potential leukemic transformation target gene in myelodysplastic syndrome |
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https://doi.org/10.18632/oncotarget.6512
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| 6566-6575 |
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| Dual mTOR inhibitor MLN0128 suppresses Merkel cell carcinoma MCC xenograft tumor growth |
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https://doi.org/10.18632/oncotarget.5878
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| 6576-6592 |
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| Presence of sst5TMD4 a truncated splice variant of the somatostatin receptor subtype 5 is associated to features of increased aggressiveness in pancreatic neuroendocrine tumors |
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https://doi.org/10.18632/oncotarget.6565
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| 6593-6608 |
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| Identification and validation of the dopamine agonist bromocriptine as a novel therapy for highrisk myelodysplastic syndromes and secondary acute myeloid leukemia |
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https://doi.org/10.18632/oncotarget.6773
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| 6609-6619 |
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| The mitochondrial genetic landscape in neuroblastoma from tumor initiation to relapse |
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https://doi.org/10.18632/oncotarget.6776
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| 6620-6625 |
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| IL6 promotes growth and epithelialmesenchymal transition of CD133+ cells of nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.6570
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| 6626-6638 |
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| Safety and efficacy of sorafenib therapy in patients with hepatocellular carcinoma: final outcome from the Chinese patient subset of the GIDEON study |
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https://doi.org/10.18632/oncotarget.6781
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| 6639-6648 |
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| MicroRNA372 inhibits endometrial carcinoma development by targeting the expression of the Ras homolog gene family member C RhoC |
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https://doi.org/10.18632/oncotarget.6544
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| 6649-6664 |
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| ERK3 regulates TDP2mediated DNA damage response and chemoresistance in lung cancer cells |
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https://doi.org/10.18632/oncotarget.6682
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| 6665-6675 |
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| MiRNAs and piRNAs from bone marrow mesenchymal stem cell extracellular vesicles induce cell survival and inhibit cell differentiation of cord blood hematopoietic stem cells: a new insight in transplantation |
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https://doi.org/10.18632/oncotarget.6791
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| 6676-6692 |
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| Annexin A1 sustains tumor metabolism and cellular proliferation upon stable loss of HIF1A |
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https://doi.org/10.18632/oncotarget.6793
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| 6693-6710 |
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| HBx regulates fatty acid oxidation to promote hepatocellular carcinoma survival during metabolic stress |
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https://doi.org/10.18632/oncotarget.6817
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| 6711-6726 |
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| HDAC inhibitors suppress cJun/Fra1mediated proliferation through transcriptionally downregulating MKK7 and Raf1 in neuroblastoma cells |
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https://doi.org/10.18632/oncotarget.6797
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| 6727-6747 |
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| TOPK promotes lung cancer resistance to EGFR tyrosine kinase inhibitors by phosphorylating and activating cJun |
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https://doi.org/10.18632/oncotarget.6826
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| 6748-6764 |
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| Is angiotensinconverting enzyme inhibitors/angiotensin receptor blockers therapy protective against prostate cancer |
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https://doi.org/10.18632/oncotarget.6837
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| 6765-6773 |
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| NG2 proteoglycan as a pericyte target for anticancer therapy by tumor vessel infarction with retargeted tissue factor |
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https://doi.org/10.18632/oncotarget.6725
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| 6774-6789 |
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| EM23 a natural sesquiterpene lactone targets thioredoxin reductase to activate JNK and cell death pathways in human cervical cancer cells |
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https://doi.org/10.18632/oncotarget.6828
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| 6790-6808 |
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| Genomewide profiling of histone H3 lysine 27 and lysine 4 trimethylation in multiple myeloma reveals the importance of Polycomb gene targeting and highlights EZH2 as a potential therapeutic target |
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https://doi.org/10.18632/oncotarget.6843
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| 6809-6823 |
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| Downregulation of C12orf59 is associated with a poor prognosis and VHL mutations in renal cell carcinoma |
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https://doi.org/10.18632/oncotarget.6829
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| 6824-6834 |
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| Transcriptomic profiling of urine extracellular vesicles reveals alterations of CDH3 in prostate cancer |
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https://doi.org/10.18632/oncotarget.6899
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| 6835-6846 |
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| Epigenetic silencing of JMJD5 promotes the proliferation of hepatocellular carcinoma cells by downregulating the transcription of CDKN1A |
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https://doi.org/10.18632/oncotarget.6867
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| 6847-6863 |
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| Gene amplification during myogenic differentiation |
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https://doi.org/10.18632/oncotarget.6845
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| 6864-6877 |
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| Targeted near infrared hyperthermia combined with immune stimulation for optimized therapeutic efficacy in thyroid cancer treatment |
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https://doi.org/10.18632/oncotarget.6901
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| 6878-6890 |
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| Decreased expression of B7H3 reduces the glycolytic capacity and sensitizes breast cancer cells to AKT/mTOR inhibitors |
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https://doi.org/10.18632/oncotarget.6902
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| 6891-6901 |
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| R152C DNA Pol β mutation impairs base excision repair and induces cellular transformation |
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https://doi.org/10.18632/oncotarget.6849
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| 6902-6915 |
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| Human carcinomaassociated mesenchymal stem cells promote ovarian cancer chemotherapy resistance via a BMP4/HH signaling loop |
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https://doi.org/10.18632/oncotarget.6870
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| 6916-6932 |
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| Nuclear translocation and activation of YAP by hypoxia contributes to the chemoresistance of SN38 in hepatocellular carcinoma cells |
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https://doi.org/10.18632/oncotarget.6903
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| 6933-6947 |
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| IRS2 silencing increases apoptosis and potentiates the effects of ruxolitinib in JAK2V617Fpositive myeloproliferative neoplasms |
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https://doi.org/10.18632/oncotarget.6851
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| 6948-6959 |
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| 4Methoxydalbergione suppresses growth and induces apoptosis in human osteosarcoma cells in vitro and in vivo xenograft model through downregulation of the JAK2/STAT3 pathway |
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https://doi.org/10.18632/oncotarget.6873
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| 6960-6971 |
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| Association of nucleotide excision repair pathway gene polymorphisms with gastric cancer and atrophic gastritis risks |
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https://doi.org/10.18632/oncotarget.6853
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| 6972-6983 |
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| Longitudinal monitoring of EGFR mutations in plasma predicts outcomes of NSCLC patients treated with EGFR TKIs: Korean Lung Cancer Consortium KLCC1202 |
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https://doi.org/10.18632/oncotarget.6874
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| 6984-6993 |
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| Local 3D matrix confinement determines division axis through cell shape |
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https://doi.org/10.18632/oncotarget.5848
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| 6994-7011 |
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| Cdk3promoted epithelialmesenchymal transition through activating AP1 is involved in colorectal cancer metastasis |
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https://doi.org/10.18632/oncotarget.6875
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| 7012-7028 |
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| Disruption of KIF3A in patientderived glioblastoma cells: effects on ciliogenesis hedgehog sensitivity and tumorigenesis |
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https://doi.org/10.18632/oncotarget.6854
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| 7029-7043 |
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| miR493 mediated DKK1 downregulation confers proliferation invasion and chemoresistance in gastric cancer cells |
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https://doi.org/10.18632/oncotarget.6951
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| 7044-7054 |
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| STAT3survivin signaling mediates a poor response to radiotherapy in HER2positive breast cancers |
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https://doi.org/10.18632/oncotarget.6855
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| 7055-7065 |
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| Tissue transglutaminase2 promotes gastric cancer progression via the ERK1/2 pathway |
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https://doi.org/10.18632/oncotarget.6883
|
| 7066-7079 |
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| A synthetic lethal screen identifies ATRinhibition as a novel therapeutic approach for POLD1deficient cancers |
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https://doi.org/10.18632/oncotarget.6857
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| 7080-7095 |
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| Survivin inhibitor YM155 suppresses gastric cancer xenograft growth in mice without affecting normal tissues |
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https://doi.org/10.18632/oncotarget.6898
|
| 7096-7109 |
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| A metaanalysis comparing cisplatinbased to carboplatinbased chemotherapy in moderate to advanced squamous cell carcinoma of head and neck SCCHN |
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https://doi.org/10.18632/oncotarget.6858
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| 7110-7119 |
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| Identifying and functionally characterizing tissuespecific and ubiquitously expressed human lncRNAs |
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https://doi.org/10.18632/oncotarget.6859
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| 7120-7133 |
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| DYRK1B as therapeutic target in Hedgehog/GLIdependent cancer cells with Smoothened inhibitor resistance |
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https://doi.org/10.18632/oncotarget.6910
|
| 7134-7148 |
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| miRNA29a as a tumor suppressor mediates PRIMA1Metinduced antimyeloma activity by targeting cMyc |
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https://doi.org/10.18632/oncotarget.6880
|
| 7149-7160 |
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| The probiotic Propionibacterium freudenreichii as a new adjuvant for TRAILbased therapy in colorectal cancer |
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https://doi.org/10.18632/oncotarget.6881
|
| 7161-7178 |
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| TRAF6 regulates melanoma invasion and metastasis through ubiquitination of Basigin |
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https://doi.org/10.18632/oncotarget.6886
|
| 7179-7192 |
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| DANGER is involved in high glucoseinduced radioresistance through inhibiting DAPKmediated anoikis in nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.6887
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| 7193-7206 |
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| MRP3 as a novel resistance factor for sorafenib in hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.6889
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| 7207-7215 |
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| Metabonomic analysis of ovarian tumour cyst fluid by proton nuclear magnetic resonance spectroscopy |
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https://doi.org/10.18632/oncotarget.6891
|
| 7216-7226 |
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| Prognostic value of tumorinfiltrating lymphocytes for patients with completely resected stage IIIAN2 nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.6979
|
| 7227-7240 |
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| Tumor vascularity and lipiodol deposition as early radiological markers for predicting risk of disease progression in patients with unresectable hepatocellular carcinoma after transarterial chemoembolization |
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https://doi.org/10.18632/oncotarget.6892
|
| 7241-7252 |
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| A novel nuclear Src and p300 signaling axis controls migratory and invasive behavior in pancreatic cancer |
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https://doi.org/10.18632/oncotarget.6635
|
| 7253-7267 |
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| Artemisininderived dimer ART838 potently inhibited human acute leukemias persisted in vivo and synergized with antileukemic drugs |
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https://doi.org/10.18632/oncotarget.6896
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| 7268-7279 |
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| CXCR2 signaling regulates KRASG12Dinduced autocrine growth of pancreatic cancer |
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https://doi.org/10.18632/oncotarget.6906
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| 7280-7296 |
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| Acyl protein thioesterase 1 and 2 APT1 APT2 inhibitors palmostatin B ML348 and ML349 have different effects on NRAS mutant melanoma cells |
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https://doi.org/10.18632/oncotarget.6907
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| 7297-7306 |
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| IL32θ inhibits stemness and epithelialmesenchymal transition of cancer stem cells via the STAT3 pathway in colon cancer |
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https://doi.org/10.18632/oncotarget.7007
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| 7307-7317 |
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| Antiovarian tumor response of donor peripheral blood mononuclear cells is due to infiltrating cytotoxic NK cells |
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https://doi.org/10.18632/oncotarget.6939
|
| 7318-7328 |
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| Crosstalk between ATF4 and MTA1/HDAC1 promotes osteosarcoma progression |
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https://doi.org/10.18632/oncotarget.6940
|
| 7329-7342 |
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| CXCR6CXCL16 axis promotes prostate cancer by mediating cytoskeleton rearrangement via Ezrin activation and αvβ3 integrin clustering |
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https://doi.org/10.18632/oncotarget.6944
|
| 7343-7353 |
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| Comparison of liver oncogenic potential among human RAS isoforms |
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https://doi.org/10.18632/oncotarget.6931
|
| 7354-7366 |
Corrections
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| Correction: Noncanonical roles of membranous lysyltRNA synthetase in transducing cellsubstrate signaling for invasive dissemination of colon cancer spheroids in 3D collagen I gels |
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https://doi.org/10.18632/oncotarget.7117
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| 7367-7367 |
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