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About The Cover
The cover for issue 44 of Oncotarget features Figure 5G, "Targeting distinct phases of the angiogenic response using anti-angiogenic agents with distinct mechanisms of action," from Brennen, et al.
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Table of Contents
Research Perspective: Immunology
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| Aspergillus fumigatus responds to natural killer NK cells with upregulation of stress related genes and inhibits the immunoregulatory function of NK cells |
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https://doi.org/10.18632/oncotarget.12616
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| 71062-71071 |
Research Papers: Gerotarget (Focus on Aging)
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| Treadmill running exercise prevents senile osteoporosis and upregulates the Wnt signaling pathway in SAMP6 mice |
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https://doi.org/10.18632/oncotarget.12125
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| 71072-71086 |
Research Papers: Pathology
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| Systematically characterizing dysfunctional long intergenic noncoding RNAs in multiple brain regions of major psychosis |
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https://doi.org/10.18632/oncotarget.12122
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| 71087-71098 |
Research Papers: Immunology
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| TIM4 is expressed on invariant NKT cells but dispensable for their development and function |
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https://doi.org/10.18632/oncotarget.12153
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| 71099-71111 |
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| Mesenchymal stem cells overexpressing Sirt1 inhibit prostate cancer growth by recruiting natural killer cells and macrophages |
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https://doi.org/10.18632/oncotarget.12737
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| 71112-71122 |
Research Papers
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| Similarity and diversity of the tumor microenvironment in multiple metastases: critical implications for overall and progressionfree survival of highgrade serous ovarian cancer |
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https://doi.org/10.18632/oncotarget.12106
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| 71123-71135 |
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| cCbl mediates the degradation of tumorigenic nuclear βcatenin contributing to the heterogeneity in Wnt activity in colorectal tumors |
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https://doi.org/10.18632/oncotarget.12107
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| 71136-71150 |
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| Suppression of endogenous lipogenesis induces reversion of the malignant phenotype and normalized differentiation in breast cancer |
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https://doi.org/10.18632/oncotarget.9463
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| 71151-71168 |
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| Low disabled2 expression promotes tumor progression and determines poor survival and high recurrence of esophageal squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.8460
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| 71169-71181 |
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| A first generation inhibitor of human Greatwall kinase enabled by structural and functional characterisation of a minimal kinase domain construct |
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https://doi.org/10.18632/oncotarget.11511
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| 71182-71197 |
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| Prognostic value of PDL1 expression in pancreatic cancer |
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https://doi.org/10.18632/oncotarget.11685
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| 71198-71210 |
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| Targeting Notch enhances the efficacy of ERK inhibitors in BRAFV600E melanoma |
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https://doi.org/10.18632/oncotarget.12078
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| 71211-71222 |
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| Impact of labelfree technologies in head and neck cancer circulating tumour cells |
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https://doi.org/10.18632/oncotarget.12086
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| 71223-71234 |
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| Profiles of miRNAs matched to biology in aromatase inhibitor resistant breast cancer |
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https://doi.org/10.18632/oncotarget.12103
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| 71235-71254 |
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| Gammainterferoninducible lysosome/endosomelocalized thiolreductase GILT has antiretroviral activity and its expression is counteracted by HIV1 |
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https://doi.org/10.18632/oncotarget.12104
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| 71255-71273 |
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| Recombinant heat shock protein 70 functional peptide and alphafetoprotein epitope peptide vaccine elicits specific antitumor immunity |
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https://doi.org/10.18632/oncotarget.12464
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| 71274-71284 |
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| Glycodelin is a potential novel followup biomarker for malignant pleural mesothelioma |
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https://doi.org/10.18632/oncotarget.12474
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| 71285-71297 |
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| Assessing angiogenic responses induced by primary human prostate stromal cells in a threedimensional fibrin matrix assay |
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https://doi.org/10.18632/oncotarget.11347
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| 71298-71308 |
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| Restoring miR122 in human stemlike hepatocarcinoma cells prompts tumor dormancy through Smadindependent TGFβ pathway |
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https://doi.org/10.18632/oncotarget.11885
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| 71309-71329 |
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| Circulating tumor cell is a common property of brain glioma and promotes the monitoring system |
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https://doi.org/10.18632/oncotarget.11114
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| 71330-71340 |
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| Halofuginone inhibits radiotherapyinduced epithelialmesenchymal transition in lung cancer |
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https://doi.org/10.18632/oncotarget.11217
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| 71341-71352 |
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| Blood RNA expression profiles undergo major changes during the seventh decade |
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https://doi.org/10.18632/oncotarget.12098
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| 71353-71361 |
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| Dormant tumor cells expressing LOXL2 acquire a stemlike phenotype mediating their transition to proliferative growth |
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https://doi.org/10.18632/oncotarget.12109
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| 71362-71377 |
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| Targeting p53deficient chronic lymphocytic leukemia cells in vitro and in vivo by ROSmediated mechanism |
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https://doi.org/10.18632/oncotarget.12110
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| 71378-71389 |
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| Xradiation enhances the collagen type I strap formation and migration potentials of colon cancer cells |
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https://doi.org/10.18632/oncotarget.12111
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| 71390-71399 |
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| STC2 promotes the epithelialmesenchymal transition of colorectal cancer cells through AKTERK signaling pathways |
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https://doi.org/10.18632/oncotarget.12147
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| 71400-71416 |
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| Acetylation of androgen receptor by ARD1 promotes dissociation from HSP90 complex and prostate tumorigenesis |
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https://doi.org/10.18632/oncotarget.12163
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| 71417-71428 |
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| Fibroblast growth factor receptor FGFR alterations in squamous differentiated bladder cancer: a putative therapeutic target for a small subgroup |
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https://doi.org/10.18632/oncotarget.12198
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| 71429-71439 |
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| Reproducibility with repeat CT in radiomics study for rectal cancer |
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https://doi.org/10.18632/oncotarget.12199
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| 71440-71446 |
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| Single nucleotide polymorphisms in microRNA genes are associated with cervical cancer susceptibility in a population from Xinjiang Uygur |
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https://doi.org/10.18632/oncotarget.12212
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| 71447-71454 |
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| CD8+/FOXP3+ ratio and PDL1 expression associated with survival in pT3N0M0 stage esophageal squamous cell cancer |
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https://doi.org/10.18632/oncotarget.12213
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| 71455-71465 |
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| Targeting endogenous DLK1 exerts antitumor effect on hepatocellular carcinoma through initiating cell differentiation |
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https://doi.org/10.18632/oncotarget.12214
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| 71466-71476 |
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| The human nucleophosmin 1 mutation A inhibits myeloid differentiation of leukemia cells by modulating miR10b |
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https://doi.org/10.18632/oncotarget.12216
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| 71477-71490 |
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| Tumorinitiating cell frequency is relevant for glioblastoma aggressiveness |
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https://doi.org/10.18632/oncotarget.11600
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| 71491-71503 |
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| MicroRNA regulatory pathway analysis identifies miR1425p as a negative regulator of TGFβ pathway via targeting SMAD3 |
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https://doi.org/10.18632/oncotarget.12229
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| 71504-71513 |
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| Paired proteomics transcriptomics and miRNomics in nonsmall cell lung cancers: known and novel signaling cascades |
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https://doi.org/10.18632/oncotarget.11723
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| 71514-71525 |
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| Prognostic nomogram for previously untreated adult patients with acute myeloid leukemia |
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https://doi.org/10.18632/oncotarget.12245
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| 71526-71535 |
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| A CD22reactive TCR from the Tcell allorepertoire for the treatment of acute lymphoblastic leukemia by TCR gene transfer |
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https://doi.org/10.18632/oncotarget.12247
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| 71536-71547 |
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| Comparative effectiveness of imageguided radiotherapy for nonoperated localized esophageal squamous cell carcinoma patients receiving concurrent chemoradiotherapy: A populationbased propensity score matched analysis |
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https://doi.org/10.18632/oncotarget.12250
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| 71548-71555 |
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| Long noncoding RNA uc345 promotes tumorigenesis of pancreatic cancer by upregulation of hnRNPL expression |
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https://doi.org/10.18632/oncotarget.12253
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| 71556-71566 |
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| Integration of zebrafish fin regeneration genes with expression data of human tumors in silico uncovers potential novel melanoma markers |
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https://doi.org/10.18632/oncotarget.12257
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| 71567-71579 |
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| Blockade of the Hedgehog pathway downregulates estrogen receptor alpha signaling in breast cancer cells |
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https://doi.org/10.18632/oncotarget.12259
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| 71580-71593 |
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| In vivo phage display screening for tumor vascular targets in glioblastoma identifies a llama nanobody against dynactin1p150Glued |
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https://doi.org/10.18632/oncotarget.12261
|
| 71594-71607 |
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| Progressive changes in composition of lymphocytes in lung tissues from patients with nonsmallcell lung cancer |
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https://doi.org/10.18632/oncotarget.12264
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| 71608-71619 |
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| Identification of novel prognostic indicators for triplenegative breast cancer patients through integrative analysis of cancer genomics data and protein interactome data |
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https://doi.org/10.18632/oncotarget.12287
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| 71620-71634 |
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| Novel role of miR29a in pancreatic cancer autophagy and its therapeutic potential |
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https://doi.org/10.18632/oncotarget.11928
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| 71635-71650 |
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| The p53 status can influence the role of Sam68 in tumorigenesis |
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https://doi.org/10.18632/oncotarget.12305
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| 71651-71659 |
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| MK8776 a novel chk1 kinase inhibitor radiosensitizes p53defective human tumor cells |
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https://doi.org/10.18632/oncotarget.12311
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| 71660-71672 |
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| IL10 secreted by M2 macrophage promoted tumorigenesis through interaction with JAK2 in glioma |
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https://doi.org/10.18632/oncotarget.12317
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| 71673-71685 |
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| Prevalence of actionable mutations and copy number alterations and the price of a genomic testing panel |
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https://doi.org/10.18632/oncotarget.11994
|
| 71686-71695 |
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| Patientderived mouse models of cancer need to be orthotopic in order to evaluate targeted antimetastatic therapy |
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https://doi.org/10.18632/oncotarget.12322
|
| 71696-71702 |
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| Gene polymorphisms are associated with clinical outcome in Chinese resected laryngeal carcinoma patients |
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https://doi.org/10.18632/oncotarget.12323
|
| 71703-71709 |
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| Fibermodified adenovirusmediated suicide gene therapy can efficiently eliminate bladder cancer cells in vitro and in vivo |
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https://doi.org/10.18632/oncotarget.12324
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| 71710-71717 |
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| MDM4 rs4245739 A > C polymorphism correlates with reduced overall cancer risk in a metaanalysis of 69477 subjects |
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https://doi.org/10.18632/oncotarget.12326
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| 71718-71726 |
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| Correlation of neuroendocrine features with prognosis of nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.12327
|
| 71727-71736 |
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| Vemurafenibresistant BRAFV600Emutated melanoma is regressed by MEKtargeting drug trametinib but not cobimetinib in a patientderived orthotopic xenograft PDOX mouse model |
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https://doi.org/10.18632/oncotarget.12328
|
| 71737-71743 |
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| RAB22A overexpression promotes the tumor growth of melanoma |
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https://doi.org/10.18632/oncotarget.12329
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| 71744-71753 |
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| Myricetin a potent natural agent for treatment of diabetic skin damage by modulating TIMP/MMPs balance and oxidative stress |
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https://doi.org/10.18632/oncotarget.12330
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| 71754-71760 |
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| Novel nomograms for survival and progression in HPV+ and HPV oropharyngeal cancer: a populationbased study of 1542 consecutive patients |
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https://doi.org/10.18632/oncotarget.12335
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| 71761-71772 |
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| Plasma and tumor levels of Lincpint are diagnostic and prognostic biomarkers for pancreatic cancer |
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https://doi.org/10.18632/oncotarget.12365
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| 71773-71781 |
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| Early responses of EGFR circulating tumor DNA to EGFR tyrosine kinase inhibitors in lung cancer treatment |
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https://doi.org/10.18632/oncotarget.12373
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| 71782-71789 |
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| JWA downregulates HER2 expression via cCbl and induces lapatinib resistance in human gastric cancer cells |
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https://doi.org/10.18632/oncotarget.12374
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| 71790-71801 |
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| Hypoxia pathway and hypoxiamediated extensive extramedullary hematopoiesis are involved in ursolic acid’s antimetastatic effect in 4T1 tumor bearing mice |
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https://doi.org/10.18632/oncotarget.12375
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| 71802-71816 |
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| Chronic lowdoserate ionising radiation affects the hippocampal phosphoproteome in the ApoE−/− Alzheimer's mouse model |
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https://doi.org/10.18632/oncotarget.12376
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| 71817-71832 |
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| A novel DNA methylation score accurately predicts death from prostate cancer in men with low to intermediate clinical risk factors |
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https://doi.org/10.18632/oncotarget.12377
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| 71833-71840 |
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| Scriptaid overcomes hypoxiainduced cisplatin resistance in both wildtype and mutant p53 lung cancer cells |
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https://doi.org/10.18632/oncotarget.12378
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| 71841-71855 |
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| Distinct biological effects of lowdose radiation on normal and cancerous human lung cells are mediated by ATM signaling |
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https://doi.org/10.18632/oncotarget.12379
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| 71856-71872 |
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| Downregulation of sphingosine kinase1 induces protective tumor immunity by promoting M1 macrophage response in melanoma |
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https://doi.org/10.18632/oncotarget.12380
|
| 71873-71886 |
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| Receptor conversion in metastatic breast cancer: a prognosticator of survival |
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https://doi.org/10.18632/oncotarget.12114
|
| 71887-71903 |
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| MDS shows a higher expression of hTERT and alternative splice variants in unactivated Tcells |
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https://doi.org/10.18632/oncotarget.12115
|
| 71904-71914 |
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| Automated analysis of acute myeloid leukemia minimal residual disease using a support vector machine |
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https://doi.org/10.18632/oncotarget.12430
|
| 71915-71921 |
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| MicroRNA130a alleviates human coronary artery endothelial cell injury and inflammatory responses by targeting PTEN via activating PI3K/Akt/eNOS signaling pathway |
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https://doi.org/10.18632/oncotarget.12431
|
| 71922-71936 |
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| Depletion of prooncogenic RUNX2 enhances gemcitabine GEM sensitivity of p53mutated pancreatic cancer Panc1 cells through the induction of proapoptotic TAp63 |
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https://doi.org/10.18632/oncotarget.12433
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| 71937-71950 |
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| Secondary malignancies after partial versus whole breast irradiation: a systematic review and metaanalysis |
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https://doi.org/10.18632/oncotarget.12442
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| 71951-71959 |
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| 18βglycyrrhetinic acid suppresses gastric cancer by activation of miR1493pWnt1 signaling |
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https://doi.org/10.18632/oncotarget.12443
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| 71960-71973 |
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| Induction treatments for acute promyelocytic leukemia: a network metaanalysis |
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https://doi.org/10.18632/oncotarget.12451
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| 71974-71986 |
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| Spc24 is required for meiotic kinetochoremicrotubule attachment and production of euploid eggs |
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https://doi.org/10.18632/oncotarget.12453
|
| 71987-71997 |
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| New strategy to rescue the inhibition of osteogenesis of human bone marrowderived mesenchymal stem cells under oxidative stress: combination of vitamin C and graphene foams |
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https://doi.org/10.18632/oncotarget.12456
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| 71998-72010 |
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| Increased gene expression noise in human cancers is correlated with low p53 and immune activities as well as late stage cancer |
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https://doi.org/10.18632/oncotarget.12457
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| 72011-72020 |
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| Discovery of cell surface vimentin targeting mAb for direct disruption of GBM tumor initiating cells |
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https://doi.org/10.18632/oncotarget.12458
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| 72021-72032 |
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| Highly elevated serum lactate dehydrogenase is associated with central nervous system relapse in patients with diffuse large Bcell lymphoma: Results of a multicenter prospective cohort study |
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https://doi.org/10.18632/oncotarget.12459
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| 72033-72043 |
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| Improved outcome in acute myeloid leukemia patients enrolled in clinical trials: A national populationbased cohort study of Danish intensive chemotherapy patients |
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https://doi.org/10.18632/oncotarget.12495
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| 72044-72056 |
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| Is alkaline phosphatase the smoking gun for highly refractory primitive leukemic cells |
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https://doi.org/10.18632/oncotarget.12497
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| 72057-72066 |
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| miR202 inhibits the progression of human cervical cancer through inhibition of cyclin D1 |
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https://doi.org/10.18632/oncotarget.12499
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| 72067-72075 |
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| Preoperative combined hemoglobin albumin lymphocyte and platelet levels predict survival in patients with locally advanced colorectal cancer |
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https://doi.org/10.18632/oncotarget.12271
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| 72076-72083 |
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| Dualstrand tumorsuppressor microRNA145 miR1455p and miR1453p coordinately targeted MTDH in lung squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.12290
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| 72084-72098 |
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| Receptor tyrosine kinase amplified gastric cancer: Clinicopathologic characteristics and proposed screening algorithm |
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https://doi.org/10.18632/oncotarget.12291
|
| 72099-72112 |
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| Myocardinrelated transcription factor A MRTFA activitydependent cell adhesion is correlated to focal adhesion kinase FAK activity |
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https://doi.org/10.18632/oncotarget.12350
|
| 72113-72130 |
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| PRMT5 competitively binds to CDK4 to promote G1S transition upon glucose induction in hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.12351
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| 72131-72147 |
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| NSAIDactivated gene 1 mediates proinflammatory signaling activation and paclitaxel chemoresistance in type I human epithelial ovarian cancer stemlike cells |
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https://doi.org/10.18632/oncotarget.12355
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| 72148-72166 |
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| A module of inflammatory cytokines defines resistance of colorectal cancer to EGFR inhibitors |
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https://doi.org/10.18632/oncotarget.12354
|
| 72167-72183 |
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| Prognostic effect of intratumoral neutrophils across histological subtypes of nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.12360
|
| 72184-72196 |
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| A strong host response and lack of MYC expression are characteristic for diffuse large B cell lymphoma transformed from nodular lymphocyte predominant Hodgkin lymphoma |
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https://doi.org/10.18632/oncotarget.12363
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| 72197-72210 |
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| Evaluation of the anatomical parameters for normal tissue sparing in the prone position radiotherapy with small sized left breasts |
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https://doi.org/10.18632/oncotarget.12662
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| 72211-72218 |
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| Prognostic value of pretreatment serum beta2 microglobulin level in advanced classical Hodgkin lymphoma treated in the modern era |
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https://doi.org/10.18632/oncotarget.12663
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| 72219-72228 |
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| Filamin A interacting protein 1like expression inhibits progression in colorectal cancer |
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https://doi.org/10.18632/oncotarget.12664
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| 72229-72241 |
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| Prognostic significance of B7H4 expression in matched primary pancreatic cancer and liver metastases |
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https://doi.org/10.18632/oncotarget.12665
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| 72242-72249 |
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| Ino80 promotes cervical cancer tumorigenesis by activating Nanog expression |
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https://doi.org/10.18632/oncotarget.12667
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| 72250-72262 |
Clinical Research Papers
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| The role of surgical intervention in primary colorectal lymphoma: A SEER populationbased analysis |
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https://doi.org/10.18632/oncotarget.12344
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| 72263-72275 |
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| Prognostic significance of preoperative aspartate aminotransferase to neutrophil ratio index in patients with hepatocellular carcinoma after hepatic resection |
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https://doi.org/10.18632/oncotarget.10848
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| 72276-72289 |
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| Negative to positive lymph node ratio is a superior predictor than traditional lymph node status in stage III colorectal cancer |
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https://doi.org/10.18632/oncotarget.10806
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| 72290-72299 |
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| A new predictive model combined of tumor size lymph nodes count and lymphovascular invasion for survival prognosis in patients with lymph nodenegative gastric cancer |
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https://doi.org/10.18632/oncotarget.11035
|
| 72300-72310 |
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| Genetic predisposition and induced proinflammatory/prooxidative status may play a role in increased atherothrombotic events in nilotinib treated chronic myeloid leukemia patients |
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https://doi.org/10.18632/oncotarget.11100
|
| 72311-72321 |
Reviews
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| Addressing intratumoral heterogeneity and therapy resistance |
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https://doi.org/10.18632/oncotarget.11875
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| 72322-72342 |
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| Transarterial radioembolization in intermediateadvanced hepatocellular carcinoma: systematic review and metaanalyses |
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https://doi.org/10.18632/oncotarget.11644
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| 72343-72355 |
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| Sex chromosome loss and the pseudoautosomal region genes in hematological malignancies |
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https://doi.org/10.18632/oncotarget.12050
|
| 72356-72372 |
Case Reports
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| Response to apatinib in chemotherapyfailed advanced spindle cell breast carcinoma |
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https://doi.org/10.18632/oncotarget.12568
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| 72373-72379 |
Corrections
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| Correction: 5Fluorouracilinduced RNA stress engages a TRAILDISCdependent apoptosis axis facilitated by p53 |
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https://doi.org/10.18632/oncotarget.12849
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| 72380-72380 |
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Oncotarget ® is a registered trademark of Rapamycin Press LLC
Impact Journals ® is a registered trademark of Rapamycin Press LLC
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