VOLUME 7 (2016)
Table of Contents
Editorial: Autophagy and Cell Death
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| Turning off the BCL2 switch to prevent intestinal tumorigenesis |
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https://doi.org/10.18632/oncotarget.8757
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| 28763-28764 |
Priority Research Papers
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| Angiomotin stabilization by tankyrase inhibitors antagonizes constitutive TEADdependent transcription and proliferation of human tumor cells with Hippo pathway core component mutations |
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https://doi.org/10.18632/oncotarget.9117
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| 28765-28782 |
Research Papers: Gerotarget (Focus on Aging)
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| Inflammatory and immune markers associated with physical frailty syndrome: findings from Singapore longitudinal aging studies |
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https://doi.org/10.18632/oncotarget.8939
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| 28783-28795 |
Research Papers: Pathology
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| MicroRNA93 inhibits ischemiareperfusion induced cardiomyocyte apoptosis by targeting PTEN |
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https://doi.org/10.18632/oncotarget.8941
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| 28796-28805 |
Research Papers: Immunology
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| Identification of the microRNA networks contributing to macrophage differentiation and function |
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https://doi.org/10.18632/oncotarget.8933
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| 28806-28820 |
Research Papers: Autophagy and Cell Death
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| Mitophagy acts as a safeguard mechanism against human vascular smooth muscle cell apoptosis induced by atherogenic lipids |
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https://doi.org/10.18632/oncotarget.8936
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| 28821-28835 |
Research Papers
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| Setdb1 a novel interactor of ΔNp63 is involved in breast tumorigenesis |
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https://doi.org/10.18632/oncotarget.7089
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| 28836-28848 |
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| The histone deacetylase inhibitor SAHA induces HSP60 nitration and its extracellular release by exosomal vesicles in human lungderived carcinoma cells |
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https://doi.org/10.18632/oncotarget.6680
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| 28849-28867 |
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| Heme oxygenase1 nuclear translocation regulates bortezomibinduced cytotoxicity and mediates genomic instability in myeloma cells |
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https://doi.org/10.18632/oncotarget.7563
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| 28868-28880 |
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| Betacellulin induces Slugmediated downregulation of Ecadherin and cell migration in ovarian cancer cells |
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https://doi.org/10.18632/oncotarget.7591
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| 28881-28890 |
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| Brachyury as a potential modulator of androgen receptor activity and a key player in therapy resistance in prostate cancer |
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https://doi.org/10.18632/oncotarget.8499
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| 28891-28902 |
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| Increased liver carcinogenesis and enrichment of stem cell properties in livers of Dickkopf 2 Dkk2 deleted mice |
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https://doi.org/10.18632/oncotarget.3293
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| 28903-28913 |
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| Mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia: a report from the Italian AIEOP study group |
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https://doi.org/10.18632/oncotarget.8016
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| 28914-28919 |
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| Integrative transcriptome analysis identifies deregulated microRNAtranscription factor networks in lung adenocarcinoma |
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https://doi.org/10.18632/oncotarget.8713
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| 28920-28934 |
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| Cinobufagin inhibits tumor growth by inducing intrinsic apoptosis through AKT signaling pathway in human nonsmall cell lung cancer cells |
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https://doi.org/10.18632/oncotarget.7898
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| 28935-28946 |
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| Western diet enhances benzoapyreneinduced colon tumorigenesis in a polyposis in rat coli PIRC rat model of colon cancer |
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https://doi.org/10.18632/oncotarget.7901
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| 28947-28960 |
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| Primary versus castrationresistant prostate cancer: modeling through novel murine prostate cancer cell lines |
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https://doi.org/10.18632/oncotarget.8436
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| 28961-28975 |
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| Functional genomics screen identifies YAP1 as a key determinant to enhance treatment sensitivity in lung cancer cells |
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https://doi.org/10.18632/oncotarget.6721
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| 28976-28988 |
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| shRNA targeting long noncoding RNA CCAT2 controlled by tetracyclineinducible system inhibits progression of bladder cancer cells |
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https://doi.org/10.18632/oncotarget.8259
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| 28989-28997 |
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| Autophagyrelated cell death by panhistone deacetylase inhibition in liver cancer |
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https://doi.org/10.18632/oncotarget.8585
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| 28998-29010 |
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| Brigatinib an anaplastic lymphoma kinase inhibitor abrogates activity and growth in ALKpositive neuroblastoma cells Drosophila and mice |
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https://doi.org/10.18632/oncotarget.8508
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| 29011-29022 |
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| LOX is a novel mitotic spindleassociated protein essential for mitosis |
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https://doi.org/10.18632/oncotarget.8628
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| 29023-29035 |
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| Chemotherapyinduced uridine diphosphate release promotes breast cancer metastasis through P2Y6 activation |
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https://doi.org/10.18632/oncotarget.8664
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| 29036-29050 |
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| CD133+ cancer stemlike cells promote migration and invasion of salivary adenoid cystic carcinoma by inducing vasculogenic mimicry formation |
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https://doi.org/10.18632/oncotarget.8665
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| 29051-29062 |
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| Targeting of short TRPM8 isoforms induces 4TMTRPM8dependent apoptosis in prostate cancer cells |
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https://doi.org/10.18632/oncotarget.8666
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| 29063-29080 |
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| SOCS1 rescues IL1βmediated suppression of epithelial sodium channel in mouse lung epithelial cells via ASK1 |
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https://doi.org/10.18632/oncotarget.8543
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| 29081-29091 |
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| Efficacy of combined gemcitabine oxaliplatin and pegaspargase Pgemox regimen in patients with newly diagnosed advancedstage or relapsed/refractory extranodal NK/Tcell lymphoma |
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https://doi.org/10.18632/oncotarget.8647
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| 29092-29101 |
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| Therapeutic potential and functional interaction of carfilzomib and vorinostat in Tcell leukemia/lymphoma |
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https://doi.org/10.18632/oncotarget.8667
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| 29102-29115 |
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| Magnolol and honokiol exert a synergistic antitumor effect through autophagy and apoptosis in human glioblastomas |
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https://doi.org/10.18632/oncotarget.8674
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| 29116-29130 |
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| Dual inhibition of AKT/FLT3ITD by A674563 overcomes FLT3 ligandinduced drug resistance in FLT3ITD positive AML |
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https://doi.org/10.18632/oncotarget.8675
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| 29131-29142 |
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| Protective effects of alpha lipoic acid on radiationinduced salivary gland injury in rats |
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https://doi.org/10.18632/oncotarget.8661
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| 29143-29153 |
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| Circulating cellfree DNA has a high degree of specificity to detect exon 19 deletions and the singlepoint substitution mutation L858R in nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.8684
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| 29154-29165 |
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| Mitochondrial DNA content in breast cancer: Impact on in vitro and in vivo phenotype and patient prognosis |
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https://doi.org/10.18632/oncotarget.8688
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| 29166-29176 |
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| Which patients with paraaortic lymph node LN16 metastasis will truly benefit from curative pancreaticoduodenectomy for pancreatic head cancer |
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https://doi.org/10.18632/oncotarget.8690
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| 29177-29186 |
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| Acquired resistance to combination treatment through loss of synergy with MEK and PI3K inhibitors in colorectal cancer |
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https://doi.org/10.18632/oncotarget.8692
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| 29187-29198 |
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| CRKL mediates EML4ALK signaling and is a potential therapeutic target for ALKrearranged lung adenocarcinoma |
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https://doi.org/10.18632/oncotarget.8638
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| 29199-29210 |
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| Whole exome sequencing of urachal adenocarcinoma reveals recurrent NF1 mutations |
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https://doi.org/10.18632/oncotarget.8640
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| 29211-29215 |
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| Silencing homeobox C6 inhibits colorectal cancer cell proliferation |
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https://doi.org/10.18632/oncotarget.8703
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| 29216-29227 |
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| sSHIP expression identifies a subset of murine basal prostate cells as neonatal stem cells |
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https://doi.org/10.18632/oncotarget.8709
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| 29228-29244 |
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| Regulation of tumor suppressor EAF2 polyubiquitination by ELL1 and SIAH2 in prostate cancer cells |
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https://doi.org/10.18632/oncotarget.8588
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| 29245-29254 |
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| SIRT1 facilitates hepatocellular carcinoma metastasis by promoting PGC1αmediated mitochondrial biogenesis |
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https://doi.org/10.18632/oncotarget.8711
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| 29255-29274 |
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| MiR320a inhibits gastric carcinoma by targeting activity in the FoxM1P27KIP1 axis |
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https://doi.org/10.18632/oncotarget.8676
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| 29275-29286 |
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| Comparative proteomics of exosomes secreted by tumoral Jurkat T cells and normal human T cell blasts unravels a potential tumorigenic role for valosincontaining protein |
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https://doi.org/10.18632/oncotarget.8678
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| 29287-29305 |
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| Nuclear factor one B NFIB encodes a subtypespecific tumour suppressor in glioblastoma |
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https://doi.org/10.18632/oncotarget.8720
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| 29306-29320 |
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| Can the microRNA expression profile help to identify novel targets for zoledronic acid in breast cancer |
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https://doi.org/10.18632/oncotarget.8722
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| 29321-29332 |
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| Reduced expression of CD109 in tumorassociated endothelial cells promotes tumor progression by paracrine interleukin8 in hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.8787
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| 29333-29345 |
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| GP73regulated oncolytic adenoviruses possess potent killing effect on human liver cancer stemlike cells |
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https://doi.org/10.18632/oncotarget.8830
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| 29346-29358 |
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| Wip1 suppresses ovarian cancer metastasis through the ATM/AKT/Snail mediated signaling |
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https://doi.org/10.18632/oncotarget.8833
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| 29359-29370 |
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| Sox9 confers stemness properties in hepatocellular carcinoma through Frizzled7 mediated Wnt/βcatenin signaling |
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https://doi.org/10.18632/oncotarget.8835
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| 29371-29386 |
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| JMJD3 promotes survival of diffuse large Bcell lymphoma subtypes via distinct mechanisms |
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https://doi.org/10.18632/oncotarget.8836
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| 29387-29399 |
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| AntimiR delivery strategies to bypass the bloodbrain barrier in glioblastoma therapy |
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https://doi.org/10.18632/oncotarget.8837
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| 29400-29411 |
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| The role of histological subtype in hormone receptor positive metastatic breast cancer: similar survival but different therapeutic approaches |
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https://doi.org/10.18632/oncotarget.8838
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| 29412-29419 |
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| Lymph node ratio may predict the benefit of postoperative radiotherapy in nodepositive cervical cancer |
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https://doi.org/10.18632/oncotarget.8840
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| 29420-29428 |
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| Pinin facilitated proliferation and metastasis of colorectal cancer through activating EGFR/ERK signaling pathway |
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https://doi.org/10.18632/oncotarget.8738
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| 29429-29439 |
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| The cellular distribution of Na+/H+ exchanger regulatory factor 1 is determined by the PDZI domain and regulates the malignant progression of breast cancer |
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https://doi.org/10.18632/oncotarget.8751
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| 29440-29453 |
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| NMRbased fecal metabolomics fingerprinting as predictors of earlier diagnosis in patients with colorectal cancer |
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https://doi.org/10.18632/oncotarget.8762
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| 29454-29464 |
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| Human growth hormone and human prolactin function as autocrine/paracrine promoters of progression of hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.8781
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| 29465-29479 |
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| B7H3 as a promising target for cytotoxicity T cell in human cancer therapy |
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https://doi.org/10.18632/oncotarget.8784
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| 29480-29491 |
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| Inhibition of proHGF activation by SRI31215 a novel approach to block oncogenic HGF/MET signaling |
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https://doi.org/10.18632/oncotarget.8785
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| 29492-29506 |
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| Knockdown of CMTM3 promotes metastasis of gastric cancer via the STAT3/Twist1/EMT signaling pathway |
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https://doi.org/10.18632/oncotarget.8789
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| 29507-29519 |
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| Targeting of Chk2 as a countermeasure to doselimiting toxicity triggered by topoisomeraseII TOP2 poisons |
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https://doi.org/10.18632/oncotarget.8790
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| 29520-29530 |
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| Deciphering the role of nuclear and cytoplasmic IKKα in skin cancer |
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https://doi.org/10.18632/oncotarget.8792
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| 29531-29547 |
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| Hypoxia promotes Rab5 activation leading to tumor cell migration invasion and metastasis |
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https://doi.org/10.18632/oncotarget.8794
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| 29548-29562 |
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| Benzyl butyl phthalate promotes breast cancer stem cell expansion via SPHK1/S1P/S1PR3 signaling |
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https://doi.org/10.18632/oncotarget.9007
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| 29563-29576 |
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| Synergistic antitumor effects of combination PI3K/mTOR and MEK inhibition SAR245409 and pimasertib in mucinous ovarian carcinoma cells by fluorescence resonance energy transfer imaging |
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https://doi.org/10.18632/oncotarget.8807
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| 29577-29591 |
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| Ninjurin1 inhibits colitismediated colon cancer development and growth by suppression of macrophage infiltration through repression of FAK signaling |
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https://doi.org/10.18632/oncotarget.9020
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| 29592-29604 |
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| Downregulation of amplified in breast cancer 1 contributes to the antitumor effects of sorafenib on human hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.8812
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| 29605-29619 |
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| TREM2 serves as a negative immune regulator through Syk pathway in an IL10 dependent manner in lung cancer |
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https://doi.org/10.18632/oncotarget.8813
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| 29620-29634 |
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| Colorectal cancer cells display chaperone dependency for the unconventional prefoldin URI1 |
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https://doi.org/10.18632/oncotarget.8816
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| 29635-29647 |
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| X66 a novel Nterminal heat shock protein 90 inhibitor exerts antitumor effects without induction of heat shock response |
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https://doi.org/10.18632/oncotarget.8818
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| 29648-29663 |
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| The La protein counteracts cisplatininduced cell death by stimulating protein synthesis of antiapoptotic factor Bcl2 |
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https://doi.org/10.18632/oncotarget.8819
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| 29664-29676 |
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| Gene expression profiling of normal thyroid tissue from patients with thyroid carcinoma |
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https://doi.org/10.18632/oncotarget.8820
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| 29677-29688 |
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| The transcription factor RUNX2 regulates receptor tyrosine kinase expression in melanoma |
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https://doi.org/10.18632/oncotarget.8822
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| 29689-29707 |
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| Nomograms for predicting longterm survival in patients with nonmetastatic nasopharyngeal carcinoma in an endemic area |
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https://doi.org/10.18632/oncotarget.8823
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| 29708-29719 |
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| Relapserelated long noncoding RNA signature to improve prognosis prediction of lung adenocarcinoma |
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https://doi.org/10.18632/oncotarget.8825
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| 29720-29738 |
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| Induction chemotherapy followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in stage IIIIVb nasopharyngeal carcinoma patients with EpsteinBarr virus DNA ≥4000 copies/ml: a matched study |
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https://doi.org/10.18632/oncotarget.8828
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| 29739-29748 |
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| Suppression of epithelialmesenchymal transition in hepatocellular carcinoma cells by Krüppellike factor 4 |
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https://doi.org/10.18632/oncotarget.8831
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| 29749-29760 |
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| Genetic changes of nonsmall cell lung cancer under neoadjuvant therapy |
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https://doi.org/10.18632/oncotarget.8858
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| 29761-29769 |
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| Two variants on T2DM susceptible gene HHEX are associated with CRC risk in a Chinese population |
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https://doi.org/10.18632/oncotarget.8865
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| 29770-29779 |
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| Impact of PI3K/AKT/mTOR pathway activation on the prognosis of patients with head and neck squamous cell carcinomas |
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https://doi.org/10.18632/oncotarget.8957
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| 29780-29793 |
Reviews
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| The effect of chemotherapy on programmed cell death 1/programmed cell death 1 ligand axis: some chemotherapeutical drugs may finally work through immune response |
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https://doi.org/10.18632/oncotarget.7631
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| 29794-29803 |
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| Notch signaling: its roles and therapeutic potential in hematological malignancies |
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https://doi.org/10.18632/oncotarget.7772
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| 29804-29823 |
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| shRNAarmed conditionally replicative adenoviruses: a promising approach for cancer therapy |
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https://doi.org/10.18632/oncotarget.8035
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| 29824-29834 |
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| Emerging preclinical pharmacological targets for Parkinson’s disease |
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https://doi.org/10.18632/oncotarget.8104
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| 29835-29863 |
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| CHIP: A new modulator of human malignant disorders |
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https://doi.org/10.18632/oncotarget.8219
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| 29864-29874 |
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