Vol 6, No 38

Catabolic pathways regulated by mTORC1 are pivotal for survival and growth of cancer cells expressing mutant Ras

Genomic binding and regulation of gene expression by the thyroid carcinoma-associated PAX8-PPARG fusion protein

Myelin oligodendrocyte glycoprotein (MOG_35-55)-induced experimental autoimmune encephalomyelitis is ameliorated in interleukin-32 alpha transgenic mice

Cancer stem cells are the cause of drug resistance in multiple myeloma: fact or fiction?

Vascular heterogeneity and targeting: the role of YKL-40 in glioblastoma vascularization

Overexpression of Mcl-1 confers resistance to BRAF^V600E inhibitors alone and in combination with MEK1/2 inhibitors in melanoma

Efficacy of CDK4 inhibition against sarcomas depends on their levels of CDK4 and p16ink4 mRNA

Exosomes enriched in stemness/metastatic-related mRNAS promote oncogenic potential in breast cancer

Whole-exome sequencing and genome-wide methylation analyses identify novel disease associated mutations and methylation patterns in idiopathic hypereosinophilic syndrome

Novel C6-substituted 1,3,4-oxadiazinones as potential anti-cancer agents

Identification of specific DNA methylation sites on the Y-chromosome as biomarker in prostate cancer

Ack1 overexpression promotes metastasis and indicates poor prognosis of hepatocellular carcinoma

Personalized comprehensive molecular profiling of high risk osteosarcoma: Implications and limitations for precision medicine

Myc promotes glutaminolysis in human neuroblastoma through direct activation of glutaminase 2

Doxycycline reverses epithelial-to-mesenchymal transition and suppresses the proliferation and metastasis of lung cancer cells

Effects of curcumin in pediatric epithelial liver tumors: inhibition of tumor growth and alpha-fetoprotein in vitro and in vivo involving the NFkappaB- and the beta-catenin pathways

A novel chemical, STF-083010, reverses tamoxifen-related drug resistance in breast cancer by inhibiting IRE1/XBP1

UCHL1 is a biomarker of aggressive multiple myeloma required for disease progression

Interleukin 6 trigged ataxia-telangiectasia mutated activation facilitates lung cancer metastasis via MMP-3/MMP-13 up-regulation

Molecular mechanisms of cisplatin cytotoxicity in acute promyelocytic leukemia cells

IL-32θ gene expression in acute myeloid leukemia suppresses TNF-α production

A biotherapy based on PSCs-in-3D spheroid-ameliorated biologics depletes in vivo cancer-sustaining stem cells

CUDR promotes liver cancer stem cell growth through upregulating TERT and C-Myc

MicroRNA-29B (mir-29b) regulates the Warburg effect in ovarian cancer by targeting AKT2 and AKT3

A set of defined oncogenic mutation alleles seems to better predict the response to cetuximab in CRC patient-derived xenograft than KRAS 12/13 mutations

Active glycolytic metabolism in CD133(+) hepatocellular cancer stem cells: regulation by MIR-122

Distribution and prognostic relevance of tumor-infiltrating lymphocytes (TILs) and PD-1/PD-L1 immune checkpoints in human brain metastases

Cetuximab enhanced the efficacy of chemotherapeutic agent in ABCB1/P-glycoprotein-overexpressing cancer cells

Bis-cyclopropane analog of disorazole C₁ is a microtubule-destabilizing agent active in ABCB1-overexpressing human colon cancer cells

Amphiregulin enhances intercellular adhesion molecule-1 expression and promotes tumor metastasis in human osteosarcoma

IDH mutation and MGMT promoter methylation in glioblastoma: results of a prospective registry

Disulfiram inhibits TGF-β-induced epithelial-mesenchymal transition and stem-like features in breast cancer via ERK/NF-κB/Snail pathway

Overexpression of WWP1 promotes tumorigenesis and predicts unfavorable prognosis in patients with hepatocellular carcinoma

Whole transcriptome sequencing identifies BCOR internal tandem duplication as a common feature of clear cell sarcoma of the kidney

Mutual regulation between CHD5 and EZH2 in hepatocellular carcinoma

­­Prevalence of deleterious ATM germline mutations in gastric cancer patients

PTTG regulates the metabolic switch of ovarian cancer cells via the c-myc pathway

Design of a peptidic inhibitor that targets the dimer interface of a prototypic galectin

The Hsp90 inhibitor SNX-7081 is synergistic with fludarabine nucleoside via DNA damage and repair mechanisms in human, p53-negative chronic lymphocytic leukemia

Heterogeneous glioblastoma cell cross-talk promotes phenotype alterations and enhanced drug resistance

Anti-cancer efficacy of SREBP inhibitor, alone or in combination with docetaxel, in prostate cancer harboring p53 mutations

The copy number of Epstein-Barr virus latent genome correlates with the oncogenicity by the activation level of LMP1 and NF-κB

LncRNA MALAT1 enhances oncogenic activities of EZH2 in castration-resistant prostate cancer

YpT1-2N0 rectal cancer after neoadjuvant chemoradiation has lower survival compared with pT1-2N0 rectal cancer

Inhibition of Eph receptor A4 by 2,5-dimethylpyrrolyl benzoic acid suppresses human pancreatic cancer growing orthotopically in nude mice

Epigenetic downregulation of the ISG15–conjugating enzyme UbcH8 impairs lipolysis and correlates with poor prognosis in nasopharyngeal carcinoma

CMTM7 knockdown increases tumorigenicity of human non-small cell lung cancer cells and EGFR-AKT signaling by reducing Rab5 activation

Germ-line variants identified by next generation sequencing in a panel of estrogen and cancer associated genes correlate with poor clinical outcome in Lynch syndrome patients

Chemical probing of HER2-amplified cancer cells identifies TORC2 as a particularly effective secondary target for combination with lapatinib

Ki67/SATB1 ratio is an independent prognostic factor of overall survival in patients with early hormone receptor-positive invasive ductal breast carcinoma

Silibinin-mediated metabolic reprogramming attenuates pancreatic cancer-induced cachexia and tumor growth

P2X3 purinergic receptor overexpression is associated with poor recurrence-free survival in hepatocellular carcinoma patients

Isothiocyanatostilbenes as novel c-Met inhibitors

Tetracycline-inducible shRNA targeting long non-coding RNA PVT1 inhibits cell growth and induces apoptosis in bladder cancer cells

Morphometric analysis of immunoselection against hyperploid cancer cells

Identifying clinically relevant drug resistance genes in drug-induced resistant cancer cell lines and post-chemotherapy tissues

Serum levels of soluble programmed death ligand 1 predict treatment response and progression free survival in multiple myeloma

Novel insights into Notum and glypicans regulation in colorectal cancer

Peptide mediated active targeting and intelligent particle size reduction-mediated enhanced penetrating of fabricated nanoparticles for triple-negative breast cancer treatment

Junctional adhesion molecule-A is overexpressed in advanced multiple myeloma and determines response to oncolytic reovirus

TIP60-miR-22 axis as a prognostic marker of breast cancer progression

E7449: A dual inhibitor of PARP1/2 and tankyrase1/2 inhibits growth of DNA repair deficient tumors and antagonizes Wnt signaling

Suppression of death receptor 5 enhances cancer cell invasion and metastasis through activation of caspase-8/TRAF2-mediated signaling

The prognostic value of peripheral CD4⁺CD25⁺ T lymphocytes among early stage and triple negative breast cancer patients receiving dendritic cells-cytokine induced killer cells infusion

ALDH1A1 mRNA expression in association with prognosis of triple-negative breast cancer

Prognostic significance of the combination of preoperative hemoglobin, albumin, lymphocyte and platelet in patients with gastric carcinoma: a retrospective cohort study

A novel prognostic biomarker SPC24 up-regulated in hepatocellular carcinoma