Oncotarget
See Duan et al. MHM, S4, and X2 cells were treated with vehicle (NT) or Nutlin (10 µM) for 24 hours. The cells were analyzed by a transmission microscope to visualize autophagic vacuoles (AVs). Representative images of early autophagic vacuoles (Avi, open arrow) and late autophagic vacuoles (Avd, filled arrow) were indicated.
HIF2a inhibitors for the treatment of VHL disease |
https://doi.org/10.18632/oncotarget.4564 Ana Martins Metelo, Haley Noonan, and Othon Iliopoulos |
23036-23037 |
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How to wake a giant |
https://doi.org/10.18632/oncotarget.5112 Ines Liebscher, Kelly R. Monk, and Torsten Schöneberg |
23038-23039 |
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Hyperinflammation, T cells, and endotoxemia |
https://doi.org/10.18632/oncotarget.5236 Makoto Inoue, and Mari L. Shinohara |
23040-23041 |
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Casp8p41 and HIV |
https://doi.org/10.18632/oncotarget.5238 Nathan W. Cummins, and Andrew D. Badley |
23042-23043 |
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Targeting brain estrogen receptor for binge eating |
https://doi.org/10.18632/oncotarget.5239 Pingwen Xu, Xuehong Cao, and Yong Xu |
23044-23045 |
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Protection of muscle nuclei |
https://doi.org/10.18632/oncotarget.5240 Talila Volk, and Shuoshuo Wang |
23046-23047 |
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HMGB1 and injury amplification |
https://doi.org/10.18632/oncotarget.5243 Peter Huebener, Celine Hernandez, and Robert F. Schwabe |
23048-23049 |
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Rapid and simple detection of gero-suppressive agents |
https://doi.org/10.18632/oncotarget.5455 Zbigniew Darzynkiewicz |
23050-23051 |
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Dual mTORC1/C2 inhibitors: gerosuppressors with potential anti-aging effect |
https://doi.org/10.18632/oncotarget.5563 Pedro Sousa-Victor, Laura García-Prat, and Pura Muñoz-Cánoves |
23052-23054 |
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Non-coding RNAs including miRNAs, piRNAs, and tRNAs in human cancer |
https://doi.org/10.18632/oncotarget.5048 Mieke Heyns, and Olga Kovalchuk |
23055-23057 |
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Regulation of Bim in Health and Disease |
https://doi.org/10.18632/oncotarget.5492 Ronit Vogt Sionov, Spiros A. Vlahopoulos, and Zvi Granot |
23058-23134 |
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p53-regulated autophagy is controlled by glycolysis and determines cell fate |
https://doi.org/10.18632/oncotarget.5218 Lei Duan, Ricardo E. Perez, Batzaya Davaadelger, Elena N. Dedkova, Lothar A. Blatter, and Carl G. Maki |
23135-23156 |
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Prognostic impact of c-Rel nuclear expression and REL amplification and crosstalk between c-Rel and the p53 pathway in diffuse large B-cell lymphoma |
https://doi.org/10.18632/oncotarget.4319 Ling Li, Zijun Y. Xu-Monette, Chi Young Ok, Alexandar Tzankov, Ganiraju C. Manyam, Ruifan Sun, Carlo Visco, Mingzhi Zhang, Santiago Montes-Moreno, Karen Dybkaer, April Chiu, Attilio Orazi, Youli Zu, Govind Bhagat, Kristy L. Richards, Eric D. Hsi, William W.L. Choi, J. Han van Krieken, Jooryung Huh, Maurilio Ponzoni, Andrés J.M. Ferreri, Michael B. Møller, Jinfeng Wang, Ben M. Parsons, Jane N. Winter, Miguel A. Piris, Lan V. Pham, L. Jeffrey Medeiros, and Ken H. Young |
23157-23180 |
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Epigenetic alterations in the suprachiasmatic nucleus and hippocampus contribute to age-related cognitive decline |
https://doi.org/10.18632/oncotarget.4036 Scott H. Deibel, Erin L. Zelinski, Robin J. Keeley, Olga Kovalchuk, and Robert J. McDonald |
23181-23203 |
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Quantifying signaling pathway activation to monitor the quality of induced pluripotent stem cells |
https://doi.org/10.18632/oncotarget.4673 Eugene Makarev, Kristen Fortney, Maria Litovchenko, Karl H. Braunewell, Alex Zhavoronkov, and Anthony Atala |
23204-23212 |
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The effects of graded levels of calorie restriction: II. Impact of short term calorie and protein restriction on circulating hormone levels, glucose homeostasis and oxidative stress in male C57BL/6 mice |
https://doi.org/10.18632/oncotarget.4003 Sharon E. Mitchell, Camille Delville, Penelope Konstantopedos, Jane Hurst, Davina Derous, Cara Green, Luonan Chen, Jackie J.D. Han, Yingchun Wang, Daniel E.L. Promislow, David Lusseau, Alex Douglas, and John R. Speakman |
23213-23237 |
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Dual mTORC1/C2 inhibitors suppress cellular geroconversion (a senescence program) |
https://doi.org/10.18632/oncotarget.4836 Olga V. Leontieva, Zoya N. Demidenko, and Mikhail V. Blagosklonny |
23238-23248 |
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Inhibition of muscle fibrosis results in increases in both utrophin levels and the number of revertant myofibers in Duchenne muscular dystrophy |
https://doi.org/10.18632/oncotarget.4021 Oshrat Levi, Olga Genin, Corrado Angelini, Orna Halevy, and Mark Pines |
23249-23260 |
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Conditional survival estimate of acute-on-chronic hepatitis B liver failure: a dynamic prediction based on a multicenter cohort |
https://doi.org/10.18632/oncotarget.4666 Ming- Hua Zheng, Sheng-Jie Wu, Ke-Qing Shi, Hua-Dong Yan, Hai Li, Gui-Qi Zhu, Yao-Yao Xie, Fa-Ling Wu, and Yong-Ping Chen |
23261-23271 |
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Na+-induced Ca2+ influx through reverse mode of Na+-Ca2+ exchanger in mouse ventricular cardiomyocyte |
https://doi.org/10.18632/oncotarget.4878 Zhen-Yu Yan, Tao Ban, Yao Fan, Wei-Ran Chen, Hong-Li Sun, Henying Chen, Quo-Fen Qiao, and Bai-Yan Li |
23272-23280 |
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AXL is an oncotarget in human colorectal cancer |
https://doi.org/10.18632/oncotarget.3962 Erika Martinelli, Giulia Martini, Claudia Cardone, Teresa Troiani, Giuseppina Liguori, Donata Vitagliano, Stefania Napolitano, Floriana Morgillo, Barbara Rinaldi, Rosa Marina Melillo, Federica Liotti, Anna Nappi, Roberto Bianco, Liberato Berrin, Loreta Pia Ciuffreda, Davide Ciardiello, Vincenzo Iaffaioli, Gerardo Botti, Fiorella Ferraiolo, and Fortunato Ciardiello |
23281-23296 |
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The role of MicroRNAs expression in laryngeal cancer |
https://doi.org/10.18632/oncotarget.4195 Xin Yu, and Zheng Li |
23297-23305 |
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Mouse models of liver cancer: Progress and recommendations |
https://doi.org/10.18632/oncotarget.4202 Li He, De-An Tian, Pei-Yuan Li, and Xing-Xing He |
23306-23322 |
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MicroRNA in pancreatic adenocarcinoma: predictive/prognostic biomarkers or therapeutic targets? |
https://doi.org/10.18632/oncotarget.4492 Oronzo Brunetti, Antonio Russo, Aldo Scarpa, Daniele Santini, Michele Reni, Alessandro Bittoni, Amalia Azzariti, Giuseppe Aprile, Sabina Delcuratolo, Michele Signorile, Antonio Gnoni, Loredana Palermo, Vito Lorusso, Stefano Cascinu, and Nicola Silvestris |
23323-23341 |
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Long non-coding RNA AOC4P suppresses hepatocellular carcinoma metastasis by enhancing vimentin degradation and inhibiting epithelial-mesenchymal transition |
https://doi.org/10.18632/oncotarget.4344 Tong-Hong Wang, Yong-Shiang Lin, Ying Chen, Chau-Ting Yeh, Yen-lin Huang, Tsung-Han Hsieh, Tzong-Ming Shieh, Chuen Hsueh, and Tse-Ching Chen |
23342-23357 |
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Androgen receptor splice variants circumvent AR blockade by microtubule-targeting agents |
https://doi.org/10.18632/oncotarget.4396 Guanyi Zhang, Xichun Liu, Jianzhuo Li, Elisa Ledet, Xavier Alvarez, Yanfeng Qi, Xueqi Fu, Oliver Sartor, Yan Dong, and Haitao Zhang |
23358-23371 |
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TET family proteins and 5-hydroxymethylcytosine in esophageal squamous cell carcinoma |
https://doi.org/10.18632/oncotarget.4281 Asuka Murata, Yoshifumi Baba, Takatsugu Ishimoto, Keisuke Miyake, Keisuke Kosumi, Kazuto Harada, Junji Kurashige, Shiro Iwagami, Yasuo Sakamoto, Yuji Miyamoto, Naoya Yoshida, Manabu Yamamoto, Shinya Oda, Masayuki Watanabe, Mitsuyoshi Nakao, and Hideo Baba |
23372-23382 |
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Extracellularly secreted APE1/Ref-1 triggers apoptosis in triple-negative breast cancer cells via RAGE binding, which is mediated through acetylation |
https://doi.org/10.18632/oncotarget.4345 Yu Ran Lee, Ki Mo Kim, Byeong Hwa Jeon, and Sunga Choi |
23383-23398 |
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High copy number variation of cancer-related microRNA genes and frequent amplification of DICER1 and DROSHA in lung cancer |
https://doi.org/10.18632/oncotarget.4351 Karol Czubak, Marzena Anna Lewandowska, Katarzyna Klonowska, Krzysztof Roszkowski, Janusz Kowalewski, Marek Figlerowicz, and Piotr Kozlowski |
23399-23416 |
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Spatiotemporal control of gene expression in bone-marrow derived cells of the tumor microenvironment induced by MRI guided focused ultrasound |
https://doi.org/10.18632/oncotarget.4288 Pierre-Yves Fortin, Matthieu Lepetit-Coiffé, Coralie Genevois, Christelle Debeissat, Bruno Quesson, Chrit T.W. Moonen, Jan Pieter Konsman, and Franck Couillaud |
23417-23426 |
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The endoplasmic reticulum mitochondrial calcium cross talk is downregulated in malignant pleural mesothelioma cells and plays a critical role in apoptosis inhibition |
https://doi.org/10.18632/oncotarget.4370 Simone Patergnani, Carlotta Giorgi, Stefania Maniero, Sonia Missiroli, Pio Maniscalco, Ilaria Bononi, Fernanda Martini, Giorgio Cavallesco, Mauro Tognon, and Paolo Pinton |
23427-23444 |
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Role and regulation of coordinately expressed de novo purine biosynthetic enzymes PPAT and PAICS in lung cancer |
https://doi.org/10.18632/oncotarget.4352 Moloy T. Goswami, Guoan Chen, Balabhadrapatruni V. S. K. Chakravarthi, Satya S. Pathi, Sharath K. Anand, Shannon L. Carskadon, Thomas J. Giordano, Arul M. Chinnaiyan, Dafydd G. Thomas, Nallasivam Palanisamy, David G. Beer, and Sooryanarayana Varambally |
23445-23461 |
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A pancreatic tumor-specific biomarker characterized in humans and mice as an immunogenic onco-glycoprotein is efficient in dendritic cell vaccination |
https://doi.org/10.18632/oncotarget.4359 Aurélie Collignon, Adriana Teodora Perles-Barbacaru, Stéphane Robert, Françoise Silvy, Emmanuelle Martinez, Isabelle Crenon, Sébastien Germain, Stéphane Garcia, Angèle Viola, Dominique Lombardo, Eric Mas, and Evelyne Béraud |
23462-23479 |
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miR-193a-3p is a potential tumor suppressor in malignant pleural mesothelioma |
https://doi.org/10.18632/oncotarget.4346 Marissa Williams, Michaela B. Kirschner, Yuen Yee Cheng, Jacky Hanh, Jocelyn Weiss, Nancy Mugridge, Casey M. Wright, Anthony Linton, Steven C. Kao, J James B. Edelman, Michael P. Vallely, Brian C. McCaughan, Wendy Cooper, Sonja Klebe, Ruby C.Y. Lin, Himanshu Brahmbhatt, Jennifer MacDiarmid, Nico van Zandwijk, and Glen Reid |
23480-23495 |
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Embigin, regulated by HOXC8, plays a suppressive role in breast tumorigenesis |
https://doi.org/10.18632/oncotarget.4360 Fengmei Chao, Jun Zhang, Yang Zhang, Houli Liu, Chenchen Yang, Juan Wang, Yanjun Guo, Xiaohong Wen, Kaiye Zhang, Bei Huang, Daihai Liu, and Yong Li |
23496-23509 |
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Cisplatin inhibits MEK1/2 |
https://doi.org/10.18632/oncotarget.4355 Tetsu Yamamoto, Igor F. Tsigelny, Andreas W. Götz, and Stephen B. Howell |
23510-23522 |
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pHLIP-mediated targeting of truncated tissue factor to tumor vessels causes vascular occlusion and impairs tumor growth |
https://doi.org/10.18632/oncotarget.4395 Suping Li, Yanhua Tian, Ying Zhao, Yinlong Zhang, Shishuai Su, Jing Wang, Meiyu Wu, Quanwei Shi, Gregory J Anderson, Johannes Thomsen, Ruifang Zhao, Tianjiao Ji, Jie Wang, and Guangjun Nie |
23523-23532 |
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miR-93/miR-106b/miR-375-CIC-CRABP1: a novel regulatory axis in prostate cancer progression |
https://doi.org/10.18632/oncotarget.4372 Nahyun Choi, Jongmin Park, Jeon-Soo Lee, Jeehyun Yoe, Guk Yeol Park, Eunjeong Kim, Hyeongrin Jeon, Yong Mee Cho, Tae-Young Roh, and Yoontae Lee |
23533-23547 |
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Hyperglycemia-induced metabolic compensation inhibits metformin sensitivity in ovarian cancer |
https://doi.org/10.18632/oncotarget.4556 Lacey M. Litchfield, Abir Mukherjee, Mark A. Eckert, Alyssa Johnson, Kathryn A. Mills, Shawn Pan, Viji Shridhar, Ernst Lengyel, and Iris L. Romero |
23548-23560 |
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A plant alkaloid, veratridine, potentiates cancer chemosensitivity by UBXN2A-dependent inhibition of an oncoprotein, mortalin-2 |
https://doi.org/10.18632/oncotarget.4452 Ammara Abdullah, Sanam Sane, Kate A. Branick, Jessica L Freeling, Hongmin Wang, Dong Zhang, and Khosrow Rezvani |
23561-23581 |
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Long non-coding RNA UCA1 induces non-T790M acquired resistance to EGFR-TKIs by activating the AKT/mTOR pathway in EGFR-mutant non-small cell lung cancer |
https://doi.org/10.18632/oncotarget.4361 Ningning Cheng, Weijing Cai, Shengxiang Ren, Xuefei Li, Qi Wang, Hui Pan, Mingchuan Zhao, Jiayu Li, Yishi Zhang, Chao Zhao, Xiaoxia Chen, Ke Fei, Caicun Zhou, and Fred R. Hirsch |
23582-23593 |
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Identification of SPHK1 as a therapeutic target and marker of poor prognosis in cholangiocarcinoma |
https://doi.org/10.18632/oncotarget.4335 Ming-Huang Chen, Chueh-Chuan Yen, Chi-Tung Cheng, Ren-Chin Wu, Shih-Chiang Huang, Chung-Shan Yu, Yi-Hsiu Chung, Chun-Yu Liu, Peter Mu-Hsin Chang, Yee Chao, Ming-Han Chen, Yu-Fen Chen, Kun-Chun Chiang, Ta-Sen Yeh, Tzu Chi Chen, Chi-Ying F. Huang, and Chun-Nan Yeh |
23594-23608 |
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The IMiDs targets IKZF-1/3 and IRF4 as novel negative regulators of NK cell-activating ligands expression in multiple myeloma |
https://doi.org/10.18632/oncotarget.4603 Cinzia Fionda, Maria Pia Abruzzese, Alessandra Zingoni, Francesca Cecere, Elisabetta Vulpis, Giovanna Peruzzi, Alessandra Soriani, Rosa Molfetta, Rossella Paolini, Maria Rosaria Ricciardi, Maria Teresa Petrucci, Angela Santoni, and Marco Cippitelli |
23609-23630 |
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A NOX2/Egr-1/Fyn pathway delineates new targets for TKI-resistant malignancies |
https://doi.org/10.18632/oncotarget.4604 Mary E. Irwin, Blake P. Johnson, Roxsan Manshouri, Hesham M. Amin, and Joya Chandra |
23631-23646 |
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Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells |
https://doi.org/10.18632/oncotarget.4640 Ananya Roy, Antoine Coum, Voichita D. Marinescu, Jelena Põlajeva, Anja Smits, Sven Nelander, Lene Uhrbom, Bengt Westermark, Karin Forsberg-Nilsson, Fredrik Pontén, and Elena Tchougounova |
23647-23661 |
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CD47 blockade inhibits tumor progression human osteosarcoma in xenograft models |
https://doi.org/10.18632/oncotarget.4282 Ji-Feng Xu, Xiao-Hong Pan, Shui-Jun Zhang, Chen Zhao, Bin-Song Qiu, Hai-Feng Gu, Jian-Fei Hong, Li Cao, Yu Chen, Bing Xia, Qin Bi, and Ya-Ping Wang |
23662-23670 |
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Chemically modified, non-anticoagulant heparin derivatives are potent galectin-3 binding inhibitors and inhibit circulating galectin-3-promoted metastasis |
https://doi.org/10.18632/oncotarget.4409 Carrie A Duckworth, Scott E Guimond, Paulina Sindrewicz, Ashley J Hughes, Neil S French, Lu-Yun Lian, Edwin A Yates, D Mark Pritchard, Jonathan M Rhodes, Jeremy E Turnbull, and Lu-Gang Yu |
23671-23687 |
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Time-course gene profiling and networks in demethylated retinoblastoma cell line |
https://doi.org/10.18632/oncotarget.4644 Federico Malusa, Monia Taranta, Nazar Zaki, Caterina Cinti, and Enrico Capobianco |
23688-23707 |
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TRIM66 overexpresssion contributes to osteosarcoma carcinogenesis and indicates poor survival outcome |
https://doi.org/10.18632/oncotarget.4291 Yu Chen, Yongfei Guo, Haisong Yang, Guodong Shi, Guohua Xu, Jiangang Shi, Na Yin, and Deyu Chen |
23708-23719 |
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Critical role of Wnt/β-catenin signaling in driving epithelial ovarian cancer platinum resistance |
https://doi.org/10.18632/oncotarget.4690 Anil Belur Nagaraj, Peronne Joseph, Olga Kovalenko, Sareena Singh, Amy Armstrong, Raymond Redline, Kimberly Resnick, Kristine Zanotti, Steven Waggoner, and Analisa DiFeo |
23720-23734 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Retargeted human avidin-CAR T cells for adoptive immunotherapy of EGFRvIII expressing gliomas and their evaluation via optical imaging |
https://doi.org/10.18632/oncotarget.4362 Kaiyu Liu, Xujie Liu, Zhiping Peng, Haojie Sun, Mingzhi Zhang, Jianning Zhang, Shuang Liu, Limin Hao, Guoqiu Lu, Kangcheng Zheng, Xikui Gong, Di Wu, Fan Wang, and Li Shen |
23735-23747 |
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COL11A1 confers chemoresistance on ovarian cancer cells through the activation of Akt/c/EBPβ pathway and PDK1 stabilization |
https://doi.org/10.18632/oncotarget.4250 Yi-Hui Wu, Tzu-Hao Chang, Yu-Fang Huang, Chien-Chin Chen, and Cheng-Yang Chou |
23748-23763 |
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Friend leukemia virus integration 1 activates the Rho GTPase pathway and is associated with metastasis in breast cancer |
https://doi.org/10.18632/oncotarget.4350 Wei Song, Wei Li, Lingyu Li, Shilin Zhang, Xu Yan, Xue Wen, Xiaoying Zhang, Huimin Tian, Ailing Li, Ji-Fan Hu, and Jiuwei Cui |
23764-23775 |
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3'3-Diindolylmethane inhibits migration, invasion and metastasis of hepatocellular carcinoma by suppressing FAK signaling |
https://doi.org/10.18632/oncotarget.4196 Wen-Xue Li, Li-Ping Chen, Min-Ying Sun, Jun-Tao Li, Hua-Zhang Liu, and Wei Zhu |
23776-23792 |
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MiR-26b/KPNA2 axis inhibits epithelial ovarian carcinoma proliferation and metastasis through downregulating OCT4 |
https://doi.org/10.18632/oncotarget.4363 Jiaxin Lin, Lan Zhang, He Huang, Yongwen Huang, Long Huang, Jianhua Wang, Shuting Huang, Li He, Yun Zhou, Weihua Jia, Jingping Yun, Rongzhen Luo, and Min Zheng |
23793-23806 |
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Targeted expression of BikDD combined with metronomic doxorubicin induces synergistic antitumor effect through Bax activation in hepatocellular carcinoma |
https://doi.org/10.18632/oncotarget.4278 Huei-Yue Dai, Hui-Yu Chen, Wei-Chen Lai, Mien-Chie Hung, and Long-Yuan Li |
23807-23819 |
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LINE-1 hypomethylation in normal colon mucosa is associated with poor survival in Chinese patients with sporadic colon cancer |
https://doi.org/10.18632/oncotarget.4450 Changhua Zhuo, Qingguo Li, Yuchen Wu, Yiwei Li, Jia Nie, Dawei Li, Junjie Peng, Peng Lian, Bin Li, Guoxiang Cai, Xinxiang Li, and Sanjun Cai |
23820-23836 |
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Direct regulation of E-cadherin by targeted histone methylation of TALE-SET fusion protein in cancer cells |
https://doi.org/10.18632/oncotarget.4340 Hyun-Soo Cho, Jeong Gu Kang, Jae-Hye Lee, Jeong-Ju Lee, Seong Kook Jeon, Jeong-Heon Ko, Dae-Soo Kim, Kun-Hyang Park, Yong-Sam Kim, and Nam-Soon Kim |
23837-23844 |
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Protein tyrosine phosphatase SHP2 promotes invadopodia formation through suppression of Rho signaling |
https://doi.org/10.18632/oncotarget.4313 Wan-Chen Tsai, Chien-Lin Chen, and Hong-Chen Chen |
23845-23856 |
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Lovastatin overcomes gefitinib resistance through TNF-α signaling in human cholangiocarcinomas with different LKB1 statuses in vitro and in vivo |
https://doi.org/10.18632/oncotarget.4408 Sheng-Huei Yang, Hung-Yun Lin, Vincent H.S. Chang, Chien-Chung Chen, Yun-Ru Liu, Jinghan Wang, Keqiang Zhang, Xiaoqing Jiang, and Yun Yen |
23857-23873 |
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miR-200c dampens cancer cell migration via regulation of protein kinase A subunits |
https://doi.org/10.18632/oncotarget.4381 Florian Christoph Sigloch, Ulrike Christina Burk, Martin Lothar Biniossek, Thomas Brabletz, and Oliver Schilling |
23874-23889 |
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NCOA1 promotes angiogenesis in breast tumors by simultaneously enhancing both HIF1α- and AP-1-mediated VEGFa transcription |
https://doi.org/10.18632/oncotarget.4341 Li Qin, Yan Xu, Yixiang Xu, Gang Ma, Lan Liao, Yelin Wu, Yi Li, Xian Wang, Xiaosong Wang, Jun Jiang, Jin Wang, and Jianming Xu |
23890-23904 |
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Molecular profiling of lung adenosquamous carcinoma: hybrid or genuine type? |
https://doi.org/10.18632/oncotarget.4163 Erik Vassella, Stephanie Langsch, Matthias S. Dettmer, Cornelia Schlup, Maja Neuenschwander, Milo Frattini, Mathias Gugger, and Stephan C. Schäfer |
23905-23916 |
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Multifaceted interactions and regulation between antizyme and its interacting proteins cyclin D1, ornithine decarboxylase and antizyme inhibitor |
https://doi.org/10.18632/oncotarget.4469 Yen-Chin Liu, Chien-Yun Lee, Chi-Li Lin, Hui-Yi Chen, Guang-Yaw Liu, and Hui-Chih Hung |
23917-23929 |
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E6 and E7 gene silencing results in decreased methylation of tumor suppressor genes and induces phenotype transformation of human cervical carcinoma cell lines |
https://doi.org/10.18632/oncotarget.4525 Liming Li, Cui Xu, Jia Long, Danbei Shen, Wuqing Zhou, Qiyan Zhou, Jia Yang, and Mingjun Jiang |
23930-23943 |
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Differential involvement of RASSF2 hypermethylation in breast cancer subtypes and their prognosis |
https://doi.org/10.18632/oncotarget.4062 Noemi Perez-Janices, Idoia Blanco-Luquin, Natalia Torrea, Therese Liechtenstein, David Escors, Alicia Cordoba, Francisco Vicente-Garcia, Isabel Jauregui, Susana De La Cruz, José Juan Illarramendi, Valle Coca, Maria Berdasco, Grazyna Kochan, Berta Ibañez, José Miguel Lera, and David Guerrero-Setas |
23944-23958 |
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Systematic dissection of phenotypic, functional, and tumorigenic heterogeneity of human prostate cancer cells |
https://doi.org/10.18632/oncotarget.4260 Xin Liu, Xin Chen, Kiera Rycaj, Hsueh-Ping Chao, Qu Deng, Collene Jeter, Can Liu, Sofia Honorio, Hangwen Li, Tammy Davis, Mahipal Suraneni, Brian Laffin, Jichao Qin, Qiuhui Li, Tao Yang, Pamela Whitney, Jianjun Shen, Jiaoti Huang, and Dean G. Tang |
23959-23986 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Targeting chemotherapy-induced PTX3 in tumor stroma to prevent the progression of drug-resistant cancers |
https://doi.org/10.18632/oncotarget.4364 Jhih-Ying Chi, Yu-Wei Hsiao, Chien-Feng Li, Yu-Chih Lo, Zu-Yau Lin, Jhen-Yi Hong, Yang-Ming Liu, Xiu Han, Shao-Ming Wang, Ben-Kuen Chen, Kelvin K. Tsai, and Ju-Ming Wang |
23987-24001 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Activation of microRNA-494-targeting Bmi1 and ADAM10 by silibinin ablates cancer stemness and predicts favourable prognostic value in head and neck squamous cell carcinomas |
https://doi.org/10.18632/oncotarget.4365 Yu-Chao Chang, Chia-Ing Jan, Chih-Yu Peng, Yu-Chi Lai, Fang-Wei Hu, and Cheng-Chia Yu |
24002-24016 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
MicroRNA-7 inhibits the stemness of prostate cancer stem-like cells and tumorigenesis by repressing KLF4/PI3K/Akt/p21 pathway |
https://doi.org/10.18632/oncotarget.4447 Yun-Li Chang, Pei-Jie Zhou, Lianzi Wei, Wang Li, Zhongzhong Ji, Yu-Xiang Fang, and Wei-Qiang Gao |
24017-24031 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Epi-reevesioside F inhibits Na+/K+-ATPase, causing cytosolic acidification, Bak activation and apoptosis in glioblastoma |
https://doi.org/10.18632/oncotarget.4429 Jui-Ling Hsu, Fan-Lun Liu, Lih-Ching Hsu, Hsun-Shuo Chang, Wohn-Jenn Leu, Chia-Chun Yu, Wei-Ling Chang, Ih-Sheng Chen, Fan-Lu Kung, and Jih-Hwa Guh |
24032-24046 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Humanized anti-hepatocyte growth factor (HGF) antibody suppresses innate irinotecan (CPT-11) resistance induced by fibroblast-derived HGF |
https://doi.org/10.18632/oncotarget.4369 Jong Kyu Woo, Ju-Hee Kang, BoRa Kim, Byung Hee Park, Kum-Joo Shin, Seong-Won Song, Jung Ju Kim, Hwan-Mook Kim, Sang-Jin Lee, and Seung Hyun Oh |
24047-24060 |
Abstract | PDF | HTML | How to cite | Order a Reprint |
Targeting stromal-induced pyruvate kinase M2 nuclear translocation impairs oxphos and prostate cancer metastatic spread |
https://doi.org/10.18632/oncotarget.4448 Elisa Giannoni, Maria Letizia Taddei, Andrea Morandi, Giuseppina Comito, Maura Calvani, Francesca Bianchini, Barbara Richichi, Giovanni Raugei, Nicholas Wong, Damu Tang, and Paola Chiarugi |
24061-24074 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Doxorubicin induces apoptosis by targeting Madcam1 and AKT and inhibiting protein translation initiation in hepatocellular carcinoma cells |
https://doi.org/10.18632/oncotarget.4373 Jiayi Wang, Lifang Ma, Xun Tang, Xiao Zhang, Yongxia Qiao, Yuling Shi, Yanfeng Xu, Zhongyong Wang, Yongchun Yu, and Fenyong Sun |
24075-24091 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
eIF4E binding protein 1 expression is associated with clinical survival outcomes in colorectal cancer |
https://doi.org/10.18632/oncotarget.4483 Min-Wu Chao, Li-Ting Wang, Chin-Yu Lai, Xiao-Ming Yang, Ya-Wen Cheng, Kuo-Hsiung Lee, Shiow-Lin Pan, and Che-Ming Teng |
24092-24104 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Oxidized low-density lipoprotein is a common risk factor for cardiovascular diseases and gastroenterological cancers via epigenomical regulation of microRNA-210 |
https://doi.org/10.18632/oncotarget.4152 Ku-Chung Chen, Yi-Chu Liao, Jaw-Yuan Wang, Ying-Chu Lin, Chung-Ho Chen, and Suh-Hang H. Juo |
24105-24118 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
DNMT1-dependent suppression of microRNA424 regulates tumor progression in human bladder cancer |
https://doi.org/10.18632/oncotarget.4431 Chun-Te Wu, Wei-Yu Lin, Ying-Hsu Chang, Paul-Yang Lin, Wen-Cheng Chen, and Miao-Fen Chen |
24119-24131 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Upregulation of FAM83D affects the proliferation and invasion of hepatocellular carcinoma |
https://doi.org/10.18632/oncotarget.4432 Weijia Liao, Weilong Liu, Xing Liu, Qing Yuan, Ying Ou, Yao Qi, Wanqiu Huang, Yun Wang, and Jian Huang |
24132-24147 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Halofuginone inhibits colorectal cancer growth through suppression of Akt/mTORC1 signaling and glucose metabolism |
https://doi.org/10.18632/oncotarget.4376 Guo-Qing Chen, Cheng-Fang Tang, Xiao-Ke Shi, Cheng-Yuan Lin, Sarwat Fatima, Xiao-Hua Pan, Da-Jian Yang, Ge Zhang, Ai-Ping Lu, Shu-Hai Lin, and Zhao-Xiang Bian |
24148-24162 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
TACC3 promotes stemness and is a potential therapeutic target in hepatocellular carcinoma |
https://doi.org/10.18632/oncotarget.4643 Dong-Sheng Zhou, Hong-Bo Wang, Zhong-Guo Zhou, Yao-Jun Zhang, Qian Zhong, Li Xu, Yue-Hua Huang, Sai-Ching Yeung, Min-Shan Chen, and Mu-Sheng Zeng |
24163-24177 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Exposure to ALS-FTD-CSF generates TDP-43 aggregates in glioblastoma cells through exosomes and TNTs-like structure |
https://doi.org/10.18632/oncotarget.4680 Xuebing Ding, Mingming Ma, Junfang Teng, Robert K.F. Teng, Shuang Zhou, Jingzheng Yin, Ekokobe Fonkem, Jason H. Huang, Erxi Wu, and Xuejing Wang |
24178-24191 |
Abstract | PDF | HTML | How to cite | Order a Reprint |
Suppression of Rituximab-resistant B-cell lymphoma with a novel multi-component anti-CD20 mAb nanocluster |
https://doi.org/10.18632/oncotarget.4206 Huafei Li, Ge Zhang, Cheng Jiang, Fulei Zhang, Changhong Ke, He Zhao, Yun Sun, Mengxin Zhao, Di Chen, Xiandi Zhu, Li Zhang, Bohua Li, Jianxin Dai, and Wei Li |
24192-24204 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Molecular spectrum of BRAF, NRAS and KRAS gene mutations in plasma cell dyscrasias: implication for MEK-ERK pathway activation |
https://doi.org/10.18632/oncotarget.4434 Marta Lionetti, Marzia Barbieri, Katia Todoerti, Luca Agnelli, Simona Marzorati, Sonia Fabris, Gabriella Ciceri, Serena Galletti, Giulia Milesi, Martina Manzoni, Mara Mazzoni, Angela Greco, Giovanni Tonon, Pellegrino Musto, Luca Baldini, and Antonino Neri |
24205-24217 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Chemokines CCL2, 3, 14 stimulate macrophage bone marrow homing, proliferation, and polarization in multiple myeloma |
https://doi.org/10.18632/oncotarget.4523 Yi Li, Yuhuan Zheng, Tianshu Li, Qiang Wang, Jianfei Qian, Yong Lu, Mingjun Zhang, Enguang Bi, Maojie Yang, Frederic Reu, Qing Yi, and Zhen Cai |
24218-24229 |
Abstract | PDF | HTML | How to cite | Order a Reprint |
The downregulation of ΔNp63 in p53-deficient mouse epidermal tumors favors metastatic behavior |
https://doi.org/10.18632/oncotarget.4353 Olga Bornachea, Fernando F. López-Calderón, Marta Dueñas, Carmen Segrelles, Corina Lorz, Cristian Suárez-Cabrera, María Marañón, Beatriz Paradela-Dobarro, Mirentxu Santos, and Jesús M. Paramio |
24230-24245 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Ceramides promote apoptosis for virus-infected lymphoma cells through induction of ceramide synthases and viral lytic gene expression |
https://doi.org/10.18632/oncotarget.4759 Lu Dai, Jimena Trillo-Tinoco, Aiping Bai, Yihan Chen, Jacek Bielawski, Luis Del Valle, Charles D. Smith, Augusto C. Ochoa, Zhiqiang Qin, and Chris Parsons |
24246-24260 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Requirement of novel amino acid fragments of orphan nuclear receptor TR3/Nur77 for its functions in angiogenesis |
https://doi.org/10.18632/oncotarget.4637 Yan Li, Pierre M. Bourbon, Marianne A. Grant, Jin Peng, Taiyang Ye, Dezheng Zhao, and Huiyan Zeng |
24261-24276 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Semi-synthetic ocotillol analogues as selective ABCB1-mediated drug resistance reversal agents |
https://doi.org/10.18632/oncotarget.4493 Yun-Kai Zhang, Hengyuan Zhang, Guan-Nan Zhang, Yi-Jun Wang, Rishil J. Kathawala, Rui Si, Bhargav A. Patel, Jinyi Xu, and Zhe-Sheng Chen |
24277-24290 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
EBV-encoded RNA via TLR3 induces inflammation in nasopharyngeal carcinoma |
https://doi.org/10.18632/oncotarget.4552 Zhi Li, Yumei Duan, Shiyue Cheng, Yan Chen, Yanxin Hu, Lu Zhang, Jiang He, Qiong Liao, Lifang Yang, and Lun-Quan Sun |
24291-24303 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
The antidiabetic compound 2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione, isolated from averrhoa carambola L., demonstrates significant antitumor potential against human breast cancer cells |
https://doi.org/10.18632/oncotarget.4475 Ying Gao, Renbin Huang, Yixuan Gong, Hyo Sim Park, Qingwei Wen, Nadin Marwan Almosnid, Uma D. Chippada-Venkata, Najlaa Abdulrhman Hosain, Eric Vick, Anthony Farone, and Elliot Altman |
24304-24319 |
Abstract | PDF | HTML | How to cite | Order a Reprint |
Detection of novel and potentially actionable anaplastic lymphoma kinase (ALK) rearrangement in colorectal adenocarcinoma by immunohistochemistry screening |
https://doi.org/10.18632/oncotarget.4462 Jeeyun Lee, Hee Cheol Kim, Jung Yong Hong, Kai Wang, Sun Young Kim, Jiryeon Jang, Seung Tae Kim, Joon Oh Park, Ho Yeong Lim, Won Ki Kang, Young Suk Park, Jiyun Lee, Woo Yong Lee, Yoon Ah Park, Jung Wook Huh, Seong Hyeon Yun, In-Gu Do, Seok Hyung Kim, Sohail Balasubramanian, Philip J. Stephens, Jeffrey S. Ross, Gang Gary Li, Zachary Hornby, Siraj M. Ali, Vincent A. Miller, Kyoung-Mee Kim, and Sai-Hong Ignatius Ou |
24320-24332 |
Abstract | PDF | HTML | How to cite | Order a Reprint |
5mC-hydroxylase activity is influenced by the PARylation of TET1 enzyme |
https://doi.org/10.18632/oncotarget.4476 Fabio Ciccarone, Elisabetta Valentini, Michele Zampieri, and Paola Caiafa |
24333-24347 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
CCR7 enhances TGF-β1-induced epithelial-mesenchymal transition and is associated with lymph node metastasis and poor overall survival in gastric cancer |
https://doi.org/10.18632/oncotarget.4484 Huiying Ma, Lingling Gao, Shichao Li, Jie Qin, Long Chen, Xinzhou Liu, Pingping Xu, Fei Wang, Honglei Xiao, Shuang Zhou, Qiang Gao, Binbin Liu, Yihong Sun, and Chunmin Liang |
24348-24360 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
eIF3 controls cell size independently of S6K1-activity |
https://doi.org/10.18632/oncotarget.4458 Katharina Schipany, Margit Rosner, Loredana Ionce, Markus Hengstschläger, and Boris Kovacic |
24361-24375 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Multimodal imaging guided preclinical trials of vascular targeting in prostate cancer |
https://doi.org/10.18632/oncotarget.4463 James Kalmuk, Margaret Folaron, Julian Buchinger, Roberto Pili, and Mukund Seshadri |
24376-24392 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Heme oxygenase-1 accelerates erastin-induced ferroptotic cell death |
https://doi.org/10.18632/oncotarget.5162 Min-Young Kwon, Eunhee Park, Seon-Jin Lee, and Su Wol Chung |
24393-24403 |
Abstract | PDF | HTML | How to cite | Order a Reprint |
Endothelial Jagged1 promotes solid tumor growth through both pro-angiogenic and angiocrine functions |
https://doi.org/10.18632/oncotarget.4380 Ana-Rita Pedrosa, Alexandre Trindade, Catarina Carvalho, José Graça, Sandra Carvalho, Maria C. Peleteiro, Ralf H. Adams, and António Duarte |
24404-24423 |
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Gene expression profiling signatures for the diagnosis and prevention of oral cavity carcinogenesis-genome-wide analysis using RNA-seq technology |
https://doi.org/10.18632/oncotarget.4420 Xiao-Han Tang, Alison M. Urvalek, Kwame Osei-Sarfo, Tuo Zhang, Theresa Scognamiglio, and Lorraine J. Gudas |
24424-24435 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Human stromal cells are required for an anti-breast cancer effect of zoledronic acid |
https://doi.org/10.18632/oncotarget.4421 Hilde H. Nienhuis, Marlous Arjaans, Hetty Timmer-Bosscha, Elisabeth G.E. de Vries, and Carolina P. Schröder |
24436-24447 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
miRNA-99b-5p suppresses liver metastasis of colorectal cancer by down-regulating mTOR |
https://doi.org/10.18632/oncotarget.4423 Wenhua Li, Jinjia Chang, Shanshan Wang, Xinyang Liu, Junjie Peng, Dan Huang, Menghong Sun, Zhiyu Chen, Wen Zhang, Weijian Guo, and Jin Li |
24448-24462 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Identification of miR-215 mediated targets/pathways via translational immunoprecipitation expression analysis (TrIP-chip) |
https://doi.org/10.18632/oncotarget.4425 Andrew Fesler, Xiao Xu, Xiao Zheng, Xiaodong Li, Jingting Jiang, James J. Russo, and Jingfang Ju |
24463-24473 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Gastric cancer associated variant of DNA polymerase beta (Leu22Pro) promotes DNA replication associated double strand breaks |
https://doi.org/10.18632/oncotarget.4426 Jenna Rozacky, Antoni A. Nemec, Joann B. Sweasy, and Dawit Kidane |
24474-24487 |
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Morphological and immunohistochemical identification of epithelial-to-mesenchymal transition in clinical prostate cancer |
https://doi.org/10.18632/oncotarget.4177 Kimberley Kolijn, Esther I. Verhoef, and Geert J.L.H. van Leenders |
24488-24498 |
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Molecular characterization of patients with pathologic complete response or early failure after neoadjuvant chemotherapy for locally advanced breast cancer using next generation sequencing and nCounter assay |
https://doi.org/10.18632/oncotarget.4119 Kyunghee Park, Moon Ki Choi, Hae Hyun Jung, In-Gu Do, Kwang Hee Lee, TaeJin Ahn, Won Ho Kil, Seok Won Kim, Jeong Eon Lee, Seok Jin Nam, Duk-Hwan Kim, Jin Seok Ahn, Young-Hyuck Im, and Yeon Hee Park |
24499-24510 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Distant metastasis risk and patterns of nasopharyngeal carcinoma in the era of IMRT: long-term results and benefits of chemotherapy |
https://doi.org/10.18632/oncotarget.4312 An-Chuan Li, Wei-Wei Xiao, Guan-Zhu Shen, Lin Wang, An-An Xu, Yan-Qing Cao, Shao-Min Huang, Cheng-Guang Lin, Fei Han, Xiao-Wu Deng, and Chong Zhao |
24511-24521 |
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Functional intronic ERCC1 polymorphism from regulomeDB can predict survival in lung cancer after surgery |
https://doi.org/10.18632/oncotarget.4083 Shin Yup Lee, Mi Jeong Hong, Hyo-Sung Jeon, Yi Young Choi, Jin Eun Choi, Hyo-Gyoung Kang, Deuk Kju Jung, Chengcheng Jin, Sook Kyung Do, Seung Soo Yoo, Yangki Seok, Eung Bae Lee, Kyung Min Shin, Ji Yun Jeong, Won Kee Lee, Jaehee Lee, Seung Ick Cha, Chang Ho Kim, Young Tae Kim, Sanghoon Jheon, and Jae Yong Park |
24522-24532 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Optimal drug regimens for primary biliary cirrhosis: a systematic review and network meta-analysis |
https://doi.org/10.18632/oncotarget.4528 Gui-Qi Zhu, Sha Huang, Gui-Qian Huang, Li-Ren Wang, Yi-Qian Lin, Yi-Ming Wu, Ke-Qing Shi, Jiang-Tao Wang, Zhi-Rui Zhou, Martin Braddock, Yong-Ping Chen, Meng-Tao Zhou, and Ming-Hua Zheng |
24533-24549 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Sorafenib continuation or discontinuation in patients with unresectable hepatocellular carcinoma after a complete response |
https://doi.org/10.18632/oncotarget.4076 Yingqiang Zhang, Wenzhe Fan, Kangshun Zhu, Ligong Lu, Sirui Fu, Jinhua Huang, Yu Wang, Jianyong Yang, Yonghui Huang, Wang Yao, and Jiaping Li |
24550-24559 |
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RNAi therapy targeting KRAS in combination with chemotherapy for locally advanced pancreatic cancer patients |
https://doi.org/10.18632/oncotarget.4183 Talia Golan, Elina Zorde Khvalevsky, Ayala Hubert, Rachel Malka Gabai, Naama Hen, Amiel Segal, Abraham Domb, Gil Harari, Eliel Ben David, Stephen Raskin, Yuri Goldes, Eran Goldin, Rami Eliakim, Maor Lahav, Yael Kopleman, Alain Dancour, Amotz Shemi, and Eithan Galun |
24560-24570 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Reproductive factors and hormone receptor status among very young (<35 years) breast cancer patients |
https://doi.org/10.18632/oncotarget.4698 Xiaoqing Jia, Guangyu Liu, Miao Mo, Jingyi Cheng, Zhenzhou Shen, and Zhimin Shao |
24571-24580 |
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Erratum: Actionable mutations in plasma cell-free DNA in patients with advanced cancers referred for experimental targeted therapies |
https://doi.org/10.18632/oncotarget.5663 Filip Janku, Philipp Angenendt, Apostolia M. Tsimberidou, Siqing Fu, Aung Naing, Gerald S. Falchook, David S. Hong, Veronica R. Holley, Goran Cabrilo, Jennifer J. Wheler, Sarina A. Piha-Paul, Ralph G. Zinner, Agop Y. Bedikian, Michael J. Overman, Bryan K. Kee, Kevin B. Kim, E. Scott Kopetz, Rajyalakshmi Luthra, Frank Diehl, Funda Meric-Bernstam, and Razelle Kurzrock |
24581-24581 |
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