Vol 8, No 59

TGFβ activates PI3K-AKT signaling via TRAF6

Therapeutic induction of high endothelial venules (HEVs) to enhance T-cell infiltration in tumors

T cells in chronic lymphocytic leukemia: can they fight?

SNPs for breast cancer risk assessment

Linking dental pathologies and cancer via Wnt signalling

MEK/ERK addiction in CNL/aCML

The ascorbate transporter SVCT2 to target microglia-dependent inflammation

Elagolix: a promising oral GnRH antagonist for endometriosis-associated pain

Progress and criticalities in the management of acute promyelocytic leukemia

A novel small-molecule arylsulfonamide causes energetic stress and suppresses breast and lung tumor growth and metastasis

Navβ2 knockdown improves cognition in APP/PS1 mice by partially inhibiting seizures and APP amyloid processing

COX-2 metabolic products, the prostaglandin I₂ and F_2α, mediate the effects of TNF-α and Zn²⁺ in stimulating the phosphorylation of Tau

Functional characterization of a short peptidoglycan recognition protein from Chinese giant salamander (Andrias davidianus)

The sexist behaviour of immune checkpoint inhibitors in cancer therapy?

Increased expression of stemness markers and altered tumor stroma in hepatocellular carcinoma under TACE-induced hypoxia: A biopsy and resection matched study

Predictive relevance of PD-L1 expression with pre-existing TILs in gastric cancer

Inhibition of aldehyde dehydrogenase 1 enhances the cytotoxic effect of retinaldehyde on A549 cancer cells

The prognostic value of over-expressed TrkB in solid tumors: a systematic review and meta-analysis

Down-regulation of HDAC3 inhibits growth of cholangiocarcinoma by inducing apoptosis

Combination of AQP1 and β-catenin expression is an independent prognosis factor in astrocytoma patients

Epidermal growth factor receptor T790M mutation as a prognostic factor in EGFR-mutant non-small cell lung cancer patients that acquired resistance to EGFR tyrosine kinase inhibitors

Radiotherapy for stage IIA rectal cancer may not benefit all

Curcumin interacts with sildenafil to kill GI tumor cells via endoplasmic reticulum stress and reactive oxygen/ nitrogen species

Laminarin counteracts diet-induced obesity associated with glucagon-like peptide-1 secretion

Inhibition of ZEB1 leads to inversion of metastatic characteristics and restoration of paclitaxel sensitivity of chronic chemoresistant ovarian carcinoma cells

Interleukin-13 reduces cardiac injury and prevents heart dysfunction in viral myocarditis via enhanced M2 macrophage polarization

Icariin induces cell differentiation and cell cycle arrest in mouse melanoma B16 cells via Erk1/2-p38-JNK-dependent pathway

NAMPT overexpression induces cancer stemness and defines a novel tumor signature for glioma prognosis

Aflatoxin B₁ affects apoptosis and expression of death receptor and endoplasmic reticulum molecules in chicken spleen

Regional lymph node involvement and outcomes in appendiceal neuroendocrine tumors: a SEER database analysis

EVI1 modulates oncogenic role of GPC1 in pancreatic carcinogenesis

RUNX1 promote invasiveness in pancreatic ductal adenocarcinoma through regulating miR-93

Histopathological expression analysis of intercellular adhesion molecule 1 (ICAM-1) along development and progression of human melanoma

Prognostic significance of total metabolic tumor volume on ¹⁸F-fluorodeoxyglucose positron emission tomography/ computed tomography in patients with diffuse large B-cell lymphoma receiving rituximab-containing chemotherapy

A bioinformatics-to-clinic sequential approach to analysis of prostate cancer biomarkers using TCGA datasets and clinical samples: a new method for precision oncology?

Myocardin and Stat3 act synergistically to inhibit cardiomyocyte apoptosis

Harnessing the heart’s resistance to malignant tumors: cardiac-derived extracellular vesicles decrease fibrosarcoma growth and leukemia-related mortality in rodents

The quinone-based derivative, HMNQ induces apoptotic and autophagic cell death by modulating reactive oxygen species in cancer cells

Silibinin protects against osteoarthritis through inhibiting the inflammatory response and cartilage matrix degradation in vitro and in vivo

Synthesis of methylprednisolone loaded ibuprofen modified dextran based nanoparticles and their application for drug delivery in acute spinal cord injury

mir-193 targets ALDH2 and contributes to toxic aldehyde accumulation and tyrosine hydroxylase dysfunction in cerebral ischemia/reperfusion injury

Apolipoprotein A-I mimetic peptide 4F suppresses tumor-associated macrophages and pancreatic cancer progression

Association of MMP-2, RB and PAI-1 with decreased recurrence-free survival and overall survival in bladder cancer patients

Podocalyxin promotes proliferation and survival in mature B-cell non-Hodgkin lymphoma cells

NLRP3-inflammasome inhibition prevents high fat and high sugar diets-induced heart damage through autophagy induction

MiR-195 suppresses the metastasis and epithelial–mesenchymal transition of hepatocellular carcinoma by inhibiting YAP

Identification of hub genes related to silicone-induced immune response in rats

Mesenchymal stem cells inhibit T cell activation by releasing TGF-β1 from TGF-β1/GARP complex

Tumor-associated macrophages promote tumor metastasis via the TGF-β/SOX9 axis in non-small cell lung cancer

R383C mutation of human CDC20 results in idiopathic non-obstructive azoospermia

Saikosaponin-d, a calcium mobilizing agent, sensitizes chemoresistant ovarian cancer cells to cisplatin-induced apoptosis by facilitating mitochondrial fission and G2/M arrest

Extracellular vesicles from KSHV-infected endothelial cells activate the complement system

High-sensitivity modified Glasgow prognostic score (HS-mGPS) Is superior to the mGPS in esophageal cancer patients treated with chemoradiotherapy

MiR-483-5p promotes IGF-II transcription and is associated with poor prognosis of hepatocellular carcinoma

ALV-J infection induces chicken monocyte death accompanied with the production of IL-1β and IL-18

PD-1/PD-L1 interaction up-regulates MDR1/P-gp expression in breast cancer cells via PI3K/AKT and MAPK/ERK pathways

Functional profiling of microtumors to identify cancer associated fibroblast-derived drug targets

Antioxidant MMCC ameliorates catch-up growth related metabolic dysfunction

Construction of a model predicting the risk of tube feeding intolerance after gastrectomy for gastric cancer based on 225 cases from a single Chinese center

The humanized anti-human AMHRII mAb 3C23K exerts an anti-tumor activity against human ovarian cancer through tumor-associated macrophages

Distinctive DNA mismatch repair and APC rare variants in African Americans with colorectal neoplasia

Tamoxifen sensitivity-related microRNA-342 is a useful biomarker for breast cancer survival

Salivary miRNA panel to detect HPV-positive and HPV-negative head and neck cancer patients

Combination therapy of exendin-4 and allogenic adipose-derived mesenchymal stem cell preserved renal function in a chronic kidney disease and sepsis syndrome setting in rats

Glipizide sensitizes lung cancer cells to TRAIL-induced apoptosis via Akt/mTOR/autophagy pathways

Apelin protects against myocardial ischemic injury by inhibiting dynamin-related protein 1

Low concentration of formononetin promotes proliferation of estrogen receptor-positive cells through an ERα-miR-375-PTEN-ERK1/2-bcl-2 pathway

Survival outcomes of double- and triple-sequential targeted therapy in patients with metastatic renal cell carcinoma: a retrospective comparison

Proteome profiling of clear cell renal cell carcinoma in von Hippel-Lindau patients highlights upregulation of Xaa-Pro aminopeptidase-1, an anti-proliferative and anti-migratory exoprotease

Associations between HVEM/LIGHT/BTLA/CD160 polymorphisms and the occurrence of antibody-mediate rejection in renal transplant recipients

Identification of potential metabolic biomarkers of cerebrospinal fluids that differentiate tuberculous meningitis from other types of meningitis by a metabolomics study

Phenformin has anti-tumorigenic effects in human ovarian cancer cells and in an orthotopic mouse model of serous ovarian cancer

The aldehyde group of gossypol induces mitochondrial apoptosis via ROS-SIRT1-p53-PUMA pathway in male germline stem cell

Digenic mutations on SCAP and AGXT2 predispose to premature myocardial infarction

Genetic predisposition to ischaemic stroke by RAGE and HMGB1 gene variants in Chinese Han population

Associations of tumor regression grade with outcomes in patients with locally advanced rectal cancer treated with preoperative two-week course of radiotherapy

Decreased expression of interferon-induced protein 2 (IFIT2) by Wnt/β-catenin signaling confers anti-apoptotic properties to colorectal cancer cells

Calcitriol induces cell senescence of kidney cancer through JMJD3 mediated histone demethylation

Systematic analysis of the expression profile of non-coding RNAs involved in ischemia/reperfusion-induced acute kidney injury in mice using RNA sequencing

Apigenin inhibits colonic inflammation and tumorigenesis by suppressing STAT3-NF-κB signaling

MicroRNA-433 inhibits oral squamous cell carcinoma cells by targeting FAK

Chondroitin sulfatases differentially regulate Wnt signaling in prostate stem cells through effects on SHP2, phospho-ERK1/2, and Dickkopf Wnt signaling pathway inhibitor (DKK3)

MAPK and ERK polymorphisms are associated with PCOS risk in Chinese women

Gsdma3 regulates hair follicle differentiation via Wnt5a-mediated non-canonical Wnt signaling pathway

The cancer-testis antigen, sperm protein 17, a new biomarker and immunological target in head and neck squamous cell carcinoma

Chronic kidney disease is associated with a risk of higher mortality following total knee arthroplasty in diabetic patients: a nationwide population-based study

Variations in plasma concentrations of tamoxifen metabolites and the effects of genetic polymorphisms on tamoxifen metabolism in Korean patients with breast cancer

An anti-CAPN5 intracellular antibody acts as an inhibitor of CAPN5-mediated neuronal degeneration

Co-targeting aurora kinase with PD-L1 and PI3K abrogates immune checkpoint mediated proliferation in peripheral T-cell lymphoma: a novel therapeutic strategy

Endothelial-derived interleukin-6 induces cancer stem cell motility by generating a chemotactic gradient towards blood vessels

Serum corin is associated with the risk of chronic heart failure

Krüppel-like factor 2 suppresses human gastric tumorigenesis through inhibiting PTEN/AKT signaling

Effect of dexmedetomidine infusion for intravenous patient-controlled analgesia on the quality of recovery after laparotomy surgery

Plasma proteomics reveals coagulation, inflammation, and metabolic shifts in H-type hypertension patients with and without acute ischemic stroke

Hydrogen sulfide attenuates chronic restrain stress-induced cognitive impairment by upreglulation of Sirt1 in hippocampus

Alcohol intake aggravates adipose browning and muscle atrophy in cancer-associated cachexia

CDK4/6 dual inhibitor abemaciclib demonstrates compelling preclinical activity against esophageal adenocarcinoma: a novel therapeutic option for a deadly disease

Caspase-4 is essential for saikosaponin a-induced apoptosis acting upstream of caspase-2 and γ-H2AX in colon cancer cells

HTR3A and HTR3E gene polymorphisms and diarrhea predominant irritable bowel syndrome risk: evidence from a meta-analysis

Comparison of efficacy between brachytherapy and penectomy in patients with penile cancer: a meta-analysis

Clinicopathological and prognostic significance of HMGA2 overexpression in gastric cancer: a meta-analysis

Prognostic role of long noncoding RNA ZFAS1 in cancer patients: a systematic review and meta-analysis

Prognostic role of long non-coding RNA TUG1 expression in various cancers: a meta-analysis

What is the best combination treatment with transarterial chemoembolization of unresectable hepatocellular carcinoma? a systematic review and network meta-analysis

Effects of levosimendan on mortality in patients with septic shock: systematic review with meta-analysis and trial sequential analysis

Long non-coding RNAs for osteosarcoma in the mouse: a meta-analysis

Increased DCLK1 correlates with the malignant status and poor outcome in malignant tumors: a meta-analysis

Association of PPARG rs 1801282 C>G polymorphism with risk of colorectal cancer: from a case-control study to a meta-analysis

Smoking and risk of cholangiocarcinoma: a systematic review and meta-analysis

Exogenous melatonin in the treatment of pain: a systematic review and meta-analysis

Comprehensive assessment of association between TLR4 gene polymorphisms and cancer risk: a systematic meta-analysis

Potassium measurements and risk of type 2 diabetes: a dose-response meta-analysis of prospective cohort studies

Significance of Ki-67 in non-muscle invasive bladder cancer patients: a systematic review and meta-analysis

Diagnostic prediction of urinary [TIMP-2] x [IGFBP7] for acute kidney injury: A meta-analysis exploring detection time and cutoff levels

Effect of hyperthermic intrathoracic chemotherapy on the malignant pleural mesothelioma: a systematic review and meta-analysis

Evaluation of the NMP22 BladderChek test for detecting bladder cancer: a systematic review and meta-analysis

The efficacy and safety of different pharmacological interventions for patients with advanced biliary tract cancer: A network meta-analysis

Network meta-analysis of the efficacy of first-line chemotherapy regimens in patients with advanced colorectal cancer

The protective effect of PFTα on alcohol-induced osteonecrosis of the femoral head

Outcome of oligoprogressing metastatic renal cell carcinoma patients treated with locoregional therapy: a multicenter retrospective analysis

Congenital heart defects of fetus after maternal exposure to organic and inorganic environmental factors: a cohort study

Optimal treatment strategies for clinically suspicious lateral pelvic lymph node metastasis in rectal cancer

Efficacy and safety of apatinib combined with transarterial chemoembolization for hepatocellular carcinoma with portal venous tumor thrombus: a retrospective study

Preoperative radiotherapy for patients with rectal cancer: a risk factor for non-reversal of ileostomy caused by stenosis or stiffness proximal to colorectal anastomosis

Clinicopathological and genetic characteristics of pulmonary large cell carcinoma under 2015 WHO classification: a pilot study

Neoadjuvant chemotherapy with different dose regimens of docetaxel, cisplatin and fluorouracil (TPF) for locoregionally advanced nasopharyngeal carcinoma: a retrospective study

Ovarian stimulated cycle: not a better alternative for women without ovulation disorder in intrauterine insemination

Does primary tumor location impact the prognosis of colorectal liver metastases patients after microwave ablation? - Lessons from 10 years’ experience

Comparison of cross-platform technologies for EGFR T790M testing in patients with non-small cell lung cancer

miRNA and lncRNA as biomarkers in cholangiocarcinoma(CCA)

Circulating biomarkers in osteosarcoma: new translational tools for diagnosis and treatment

Recent advances on uric acid transporters

Challenges and future of biomarker tests in the era of precision oncology: Can we rely on immunohistochemistry (IHC) or fluorescence in situ hybridization (FISH) to select the optimal patients for matched therapy?

The role of microbiota in the pathogenesis of schizophrenia and major depressive disorder and the possibility of targeting microbiota as a treatment option

Venom-based peptide therapy: insights into anti-cancer mechanism

A molecular view of the radioresistance of gliomas