Oncotarget

View Archive »

About The Cover

The cover for issue 59 of Oncotarget features Figure 4A, "Knockdown of Glut-1 expression by siGlut-1 was verified by immunofluorescent staining in tumor cells after 48 h. The nuclei of tumor cells were counter-stained with DAPI," from Dai, et al.

Table of Contents

Editorial

Liraglutide: another reason to target prediabetes

https://doi.org/10.18632/oncotarget.22256

Conor F. Murphy, Neil G. Docherty, and Carel W. le Roux
99203-99204
Abstract  |  PDF  |  How to cite

TGFβ activates PI3KAKT signaling via TRAF6

https://doi.org/10.18632/oncotarget.22275

Jie Song, and Maréne Landström
99205-99206
Abstract  |  PDF  |  How to cite

Therapeutic induction of high endothelial venules HEVs to enhance Tcell infiltration in tumors

https://doi.org/10.18632/oncotarget.22276

Elizabeth Allen, Rindert Missiaen, and Gabriele Bergers
99207-99208
Abstract  |  PDF  |  How to cite

T cells in chronic lymphocytic leukemia: can they fight

https://doi.org/10.18632/oncotarget.22277

Anna Vardi, Kostas Stamatopoulos, and Anastasia Hadzidimitriou
99209-99210
Abstract  |  PDF  |  How to cite

SNPs for breast cancer risk assessment

https://doi.org/10.18632/oncotarget.22278

Jack Cuzick, Adam Brentnall, and Mitchell Dowsett
99211-99212
Abstract  |  PDF  |  How to cite

Linking dental pathologies and cancer via Wnt signalling

https://doi.org/10.18632/oncotarget.22281

Pierfrancesco Pagella, Claudio Cantù, and Thimios A. Mitsiadis
99213-99214
Abstract  |  PDF  |  How to cite

MEK/ERK addiction in CNL/aCML

https://doi.org/10.18632/oncotarget.22283

Meenu Kesarwani, Zachary Kincaid, and Mohammad Azam
99215-99216
Abstract  |  PDF  |  How to cite

The ascorbate transporter SVCT2 to target microgliadependent inflammation

https://doi.org/10.18632/oncotarget.22306

Camila C. Portugal, Renato Socodato, and João B. Relvas
99217-99218
Abstract  |  PDF  |  How to cite

Elagolix: a promising oral GnRH antagonist for endometriosisassociated pain

https://doi.org/10.18632/oncotarget.22381

Erica C. Dun, and Hugh S. Taylor
99219-99220
Abstract  |  PDF  |  How to cite

Progress and criticalities in the management of acute promyelocytic leukemia

https://doi.org/10.18632/oncotarget.22385

Francesco Lo-Coco, Laura Cicconi, and Maria Teresa Voso
99221-99222
Abstract  |  PDF  |  How to cite

Research Perspectives

Metabolomic mapping of cancer stem cells for reducing and exploiting tumor heterogeneity

https://doi.org/10.18632/oncotarget.21834

Elisabet Cuyàs, Sara Verdura, Salvador Fernández-Arroyo, Joaquim Bosch-Barrera, Begoña Martin-Castillo, Jorge Joven, and Javier A. Menendez
99223-99236
Abstract  |  PDF  |  Full Text  |  How to cite

Priority Research Papers

Comparative analysis of primary versus relapse/refractory DLBCL identifies shifts in mutation spectrum

https://doi.org/10.18632/oncotarget.18502

Danielle M. Greenawalt, Winnie S. Liang, Sakina Saif, Justin Johnson, Petar Todorov, Austin Dulak, Daniel Enriquez, Rebecca Halperin, Ambar Ahmed, Vladislav Saveliev, John Carpten, David Craig, J. Carl Barrett, Brian Dougherty, Michael Zinda, Stephen Fawell, Jonathan R. Dry, and Kate Byth
99237-99244
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A novel smallmolecule arylsulfonamide causes energetic stress and suppresses breast and lung tumor growth and metastasis

https://doi.org/10.18632/oncotarget.22104

Xin Dai, Stefan Kaluz, Ying Jiang, Lei Shi, DeAngelo Mckinley, Yingzhe Wang, Binghe Wang, Erwin G. Van Meir, and Chalet Tan
99245-99260
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Priority Research Papers: Gerotarget

Constitutive Cyclin O deficiency results in penetrant hydrocephalus impaired growth and infertility

https://doi.org/10.18632/oncotarget.21818

Marc Núnez-Ollé, Carole Jung, Berta Terré, Norman A. Balsiger, Cristina Plata, Ramon Roset, Carlos Pardo-Pastor, Marta Garrido, Santiago Rojas, Francesc Alameda, Josep Lloreta, Juan Martín-Caballero, Juana M. Flores, Travis H. Stracker, Miguel A. Valverde, Francisco J. Muñoz, and Gabriel Gil-Gómez
99261-99273
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Gerotarget (Focus on Aging)

GULP1/CED6 ameliorates amyloidβ toxicity in a Drosophila model of Alzheimer’s disease

https://doi.org/10.18632/oncotarget.20062

Wai Yin Vivien Chiu, Alex Chun Koon, Jacky Chi Ki Ngo, Ho Yin Edwin Chan, and Kwok-Fai Lau
99274-99283
Abstract  |  PDF  |  Full Text  |  How to cite

Navβ2 knockdown improves cognition in APP/PS1 mice by partially inhibiting seizures and APP amyloid processing

https://doi.org/10.18632/oncotarget.21849

Tao Hu, Zhangang Xiao, Rui Mao, Bo Chen, Min-Nan Lu, Jun Tong, Rong Mei, Shan-Shan Li, Zhi-Cheng Xiao, Lian-Feng Zhang, and Yan-Bin Xiyang
99284-99295
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

COX2 metabolic products the prostaglandin I2 and F2α mediate the effects of TNFα and Zn2+ in stimulating the phosphorylation of Tau

https://doi.org/10.18632/oncotarget.21853

Yue Wang, Pei-Pei Guan, Xin Yu, Yan-Su Guo, Ying-Jie Zhang, Zhan-You Wang, and Pu Wang
99296-99311
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers: Immunology

Deep sequencing of the T cell receptor β repertoire reveals signature patterns and clonal drift in atherosclerotic plaques and patients

https://doi.org/10.18632/oncotarget.19892

Zongwei Lin, Shao Qian, Yan Gong, Jianwei Ren, Lixia Zhao, Dongxiao Wang, Xiaowei Wang, Yun Zhang, Zhe Wang, and Qunye Zhang
99312-99322
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Functional characterization of a short peptidoglycan recognition protein from Chinese giant salamander Andrias davidianus

https://doi.org/10.18632/oncotarget.21470

Zhitao Qi, Shisi Ren, Qihuan Zhang, Jun Zou, Qiaoqing Xu, Zisheng Wang, Guo Qiao, Pin Nie, and Mingxian Chang
99323-99335
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The sexist behaviour of immune checkpoint inhibitors in cancer therapy

https://doi.org/10.18632/oncotarget.22242

Andrea Botticelli, Concetta Elisa Onesti, Ilaria Zizzari, Bruna Cerbelli, Paolo Sciattella, Mario Occhipinti, Michela Roberto, Francesca Di Pietro, Adriana Bonifacino, Michele Ghidini, Patrizia Vici, Laura Pizzuti, Chiara Napoletano, Lidia Strigari, Federica Mazzuca, Marianna Nuti, and Paolo Marchetti
99336-99346
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers

Effects of nicorandil on PI3K/Akt signaling pathway and its antiapoptotic mechanisms in coronary microembolization in rats

https://doi.org/10.18632/oncotarget.19966

Qiang Su, Lang Li, Jinmin Zhao, Yuhan Sun, and Huafeng Yang
99347-99358
Abstract  |  PDF  |  Full Text  |  How to cite

Increased expression of stemness markers and altered tumor stroma in hepatocellular carcinoma under TACEinduced hypoxia: A biopsy and resection matched study

https://doi.org/10.18632/oncotarget.22078

Ji Hae Nahm, Hyungjin Rhee, Haeryoung Kim, Jeong Eun Yoo, Jee San Lee, Youngsic Jeon, Gi Hong Choi, and Young Nyun Park
99359-99371
Abstract  |  PDF  |  Full Text  |  How to cite

Predictive relevance of PDL1 expression with preexisting TILs in gastric cancer

https://doi.org/10.18632/oncotarget.22079

Xiaoli Ju, Rong Shen, Pan Huang, Jianhua Zhai, Xiaobin Qian, Qiang Wang, and Miao Chen
99372-99381
Abstract  |  PDF  |  Full Text  |  How to cite

Inhibition of aldehyde dehydrogenase 1 enhances the cytotoxic effect of retinaldehyde on A549 cancer cells

https://doi.org/10.18632/oncotarget.19544

Jin Won Park, Kyung-Ho Jung, Jin-Hee Lee, Seung Hwan Moon, Young Seok Cho, and Kyung-Han Lee
99382-99393
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The prognostic value of overexpressed TrkB in solid tumors: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.19561

Chunze Zhang, Xiaoting Li, Dan Gao, Haihua Ruan, Zhenzhen Lin, Xiaobo Li, Guang Liu, Zhicheng Ma, and Xichuan Li
99394-99401
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Downregulation of HDAC3 inhibits growth of cholangiocarcinoma by inducing apoptosis

https://doi.org/10.18632/oncotarget.19660

Mingming Zhang, Yuyao Yin, Robert G. Dorfman, Tianhui Zou, Yida Pan, Yang Li, Yuming Wang, Qian Zhou, Lixing Zhou, Bo Kong, Helmut Friess, Jun Zhang, Shimin Zhao, Lei Wang, and Xiaoping Zou
99402-99413
Abstract  |  PDF  |  Full Text  |  How to cite

Combination of AQP1 and βcatenin expression is an independent prognosis factor in astrocytoma patients

https://doi.org/10.18632/oncotarget.19562

Huikun Zhang, Fengxia Qin, Limin Yang, Jia He, Xiaoli Liu, Ying Shao, Zhifang Guo, Ming Zhang, Wenliang Li, Li Fu, Feng Gu, and Yongjie Ma
99414-99428
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Epidermal growth factor receptor T790M mutation as a prognostic factor in EGFRmutant nonsmall cell lung cancer patients that acquired resistance to EGFR tyrosine kinase inhibitors

https://doi.org/10.18632/oncotarget.19681

Guangzhi Ma, Jing Zhang, Hai Jiang, Nannan Zhang, Liyuan Yin, Wen Li, and Qinghua Zhou
99429-99437
Abstract  |  PDF  |  Full Text  |  How to cite

Radiotherapy for stage IIA rectal cancer may not benefit all

https://doi.org/10.18632/oncotarget.19683

Xiang Hu, Ya-Qi Li, Qing-Guo Li, Yan-Lei Ma, Jun-Jie Peng, and San-Jun Cai
99438-99450
Abstract  |  PDF  |  Full Text  |  How to cite

Curcumin interacts with sildenafil to kill GI tumor cells via endoplasmic reticulum stress and reactive oxygen/ nitrogen species

https://doi.org/10.18632/oncotarget.19807

Jane L. Roberts, Andrew Poklepovic, and Laurence Booth
99451-99469
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Laminarin counteracts dietinduced obesity associated with glucagonlike peptide1 secretion

https://doi.org/10.18632/oncotarget.19957

Liusong Yang, Lina Wang, Canjun Zhu, Junguo Wu, Yexian Yuan, Lulu Yu, Yaqiong Xu, Jingren Xu, Tao Wang, Zhengrui Liao, Songbo Wang, Xiaotong Zhu, Ping Gao, Yongliang Zhang, Xiuqi Wang, Qingyan Jiang, and Gang Shu
99470-99481
Abstract  |  PDF  |  Full Text  |  How to cite

Inhibition of ZEB1 leads to inversion of metastatic characteristics and restoration of paclitaxel sensitivity of chronic chemoresistant ovarian carcinoma cells

https://doi.org/10.18632/oncotarget.20107

Jun Sakata, Fumi Utsumi, Shiro Suzuki, Kaoru Niimi, Eiko Yamamoto, Kiyosumi Shibata, Takeshi Senga, Fumitaka Kikkawa, and Hiroaki Kajiyama
99482-99494
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Interleukin13 reduces cardiac injury and prevents heart dysfunction in viral myocarditis via enhanced M2 macrophage polarization

https://doi.org/10.18632/oncotarget.20111

Honghui Yang, Yan Chen, and Chuanyu Gao
99495-99503
Abstract  |  PDF  |  Full Text  |  How to cite

Icariin induces cell differentiation and cell cycle arrest in mouse melanoma B16 cells via Erk1/2p38JNKdependent pathway

https://doi.org/10.18632/oncotarget.20118

Dan Wang, Wenjuan Xu, Xiaoyu Chen, Jichun Han, Lina Yu, Caixia Gao, Wenjin Hao, Xiaona Liu, Qiusheng Zheng, and Defang Li
99504-99513
Abstract  |  PDF  |  Full Text  |  How to cite

NAMPT overexpression induces cancer stemness and defines a novel tumor signature for glioma prognosis

https://doi.org/10.18632/oncotarget.20577

Antonio Lucena-Cacace, Daniel Otero-Albiol, Manuel P. Jiménez-García, Javier Peinado-Serrano, and Amancio Carnero
99514-99530
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Aflatoxin B1 affects apoptosis and expression of death receptor and endoplasmic reticulum molecules in chicken spleen

https://doi.org/10.18632/oncotarget.20595

Panpan Zhu, Zhicai Zuo, Zhixiang Zheng, Fengyuan Wang, Xi Peng, Jing Fang, Hengmin Cui, Caixia Gao, Hetao Song, Yi Zhou, and Xici Liu
99531-99540
Abstract  |  PDF  |  Full Text  |  How to cite

Regional lymph node involvement and outcomes in appendiceal neuroendocrine tumors: a SEER database analysis

https://doi.org/10.18632/oncotarget.20362

Amir Mehrvarz Sarshekeh, Shailesh Advani, Daniel M. Halperin, Claudius Conrad, Chan Shen, James C. Yao, and Arvind Dasari
99541-99551
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

EVI1 modulates oncogenic role of GPC1 in pancreatic carcinogenesis

https://doi.org/10.18632/oncotarget.20601

Mariko Tanaka, Shumpei Ishikawa, Tetsuo Ushiku, Teppei Morikawa, Takayuki Isagawa, Makoto Yamagishi, Hiroyuki Yamamoto, Hiroto Katoh, Kimiko Takeshita, Junichi Arita, Yoshihiro Sakamoto, Kiyoshi Hasegawa, Norihiro Kokudo, and Masashi Fukayama
99552-99566
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

RUNX1 promote invasiveness in pancreatic ductal adenocarcinoma through regulating miR93

https://doi.org/10.18632/oncotarget.20433

Yin Cheng, Haiyan Yang, Yang Sun, Hongkai Zhang, Shuangni Yu, Zhaohui Lu, and Jie Chen
99567-99579
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Histopathological expression analysis of intercellular adhesion molecule 1 ICAM1 along development and progression of human melanoma

https://doi.org/10.18632/oncotarget.20884

Gilli Galore-Haskel, Erez N. Baruch, Amy L. Berg, Iris Barshack, Itzhak Zilinsky, Camila Avivi, Michal J. Besser, Jacob Schachter, and Gal Markel
99580-99586
Abstract  |  PDF  |  Full Text  |  How to cite

Prognostic significance of total metabolic tumor volume on 18Ffluorodeoxyglucose positron emission tomography/ computed tomography in patients with diffuse large Bcell lymphoma receiving rituximabcontaining chemotherapy

https://doi.org/10.18632/oncotarget.20447

Chin-Chuan Chang, Shih-Feng Cho, Ya-Wen Chuang, Chia-Yang Lin, Shu-Min Chang, Wen-Ling Hsu, and Ying-Fong Huang
99587-99600
Abstract  |  PDF  |  Full Text  |  How to cite

A bioinformaticstoclinic sequential approach to analysis of prostate cancer biomarkers using TCGA datasets and clinical samples: a new method for precision oncology

https://doi.org/10.18632/oncotarget.20448

Hidekazu Yoshie, Anna S. Sedukhina, Kimino Minagawa, Keiko Oda, Shigeko Ohnuma, Nobuyuki Yanagisawa, Ichiro Maeda, Masayuki Takagi, Hiroya Kudo, Ryuto Nakazawa, Hideo Sasaki, Toshio Kumai, Tatsuya Chikaraishi, and Ko Sato
99601-99611
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Myocardin and Stat3 act synergistically to inhibit cardiomyocyte apoptosis

https://doi.org/10.18632/oncotarget.20450

Yuan Xiang, Xing-Hua Liao, Jia-Peng Li, Hui Li, Huan Qin, Ao Yao, Cheng-Xi Yu, Peng Hu, Wei Guo, Chao-Jiang Gu, and Tong-Cun Zhang
99612-99623
Abstract  |  PDF  |  Full Text  |  How to cite

Harnessing the heart’s resistance to malignant tumors: cardiacderived extracellular vesicles decrease fibrosarcoma growth and leukemiarelated mortality in rodents

https://doi.org/10.18632/oncotarget.20454

Lilian Grigorian-Shamagian, Soraya Fereydooni, Weixin Liu, Antonio Echavez, and Eduardo Marbán
99624-99636
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The quinonebased derivative HMNQ induces apoptotic and autophagic cell death by modulating reactive oxygen species in cancer cells

https://doi.org/10.18632/oncotarget.21005

Eun Byul Lee, Min Gyeong Cheon, Jun Cui, Yoo Jin Lee, Eun Kyoung Seo, and Ho Hee Jang
99637-99648
Abstract  |  PDF  |  Full Text  |  How to cite

Silibinin protects against osteoarthritis through inhibiting the inflammatory response and cartilage matrix degradation in vitro and in vivo

https://doi.org/10.18632/oncotarget.20587

Wenhao Zheng, Zhenhua Feng, Yiting Lou, Chunhui Chen, Chuanxu Zhang, Zhenyu Tao, Hang Li, Liang Cheng, and Xiaozhou Ying
99649-99665
Abstract  |  PDF  |  Full Text  |  How to cite

Synthesis of methylprednisolone loaded ibuprofen modified dextran based nanoparticles and their application for drug delivery in acute spinal cord injury

https://doi.org/10.18632/oncotarget.20649

Lei Qi, Haiyan Jiang, Xiaohui Cui, Guiwen Liang, Ming Gao, Zhongwei Huang, and Qinghua Xi
99666-99680
Abstract  |  PDF  |  Full Text  |  How to cite

mir193 targets ALDH2 and contributes to toxic aldehyde accumulation and tyrosine hydroxylase dysfunction in cerebral ischemia/reperfusion injury

https://doi.org/10.18632/oncotarget.21129

Li Mao, Mei-Ling Zuo, Guo-Huang Hu, Xiao-Ming Duan, and Zhong-Bao Yang
99681-99692
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Apolipoprotein AI mimetic peptide 4F suppresses tumorassociated macrophages and pancreatic cancer progression

https://doi.org/10.18632/oncotarget.21157

Meiyu Peng, Qi Zhang, Yingnan Cheng, Shuyu Fu, Huipeng Yang, Xiangdong Guo, Jieyou Zhang, Lina Wang, Lijuan Zhang, Zhenyi Xue, Yan Li, Yurong Da, Zhi Yao, Liang Qiao, and Rongxin Zhang
99693-99706
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Association of MMP2 RB and PAI1 with decreased recurrencefree survival and overall survival in bladder cancer patients

https://doi.org/10.18632/oncotarget.20686

Owen T.M. Chan, Hideki Furuya, Ian Pagano, Yoshiko Shimizu, Kanani Hokutan, Lars Dyrskjøt, Jørgen Bjerggaard Jensen, Per-Uno Malmstrom, Ulrika Segersten, Filip Janku, and Charles J. Rosser
99707-99721
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Podocalyxin promotes proliferation and survival in mature Bcell nonHodgkin lymphoma cells

https://doi.org/10.18632/oncotarget.21283

Estíbaliz Tamayo-Orbegozo, Laura Amo, Marta Riñón, Naiara Nieto, Elena Amutio, Natalia Maruri, Miren Solaun, Arantza Arrieta, and Susana Larrucea
99722-99739
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

NLRP3inflammasome inhibition prevents high fat and high sugar dietsinduced heart damage through autophagy induction

https://doi.org/10.18632/oncotarget.20763

Luís E. Pavillard, Diego Cañadas-Lozano, Elísabet Alcocer-Gómez, Fabiola Marín-Aguilar, Sheila Pereira, Avril A.B. Robertson, Jordi Muntané, Bernhard Ryffel, Matthew A. Cooper, José L. Quiles, Pedro Bullón, Jesús Ruiz-Cabello, and Mario D. Cordero
99740-99756
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR195 suppresses the metastasis and epithelial–mesenchymal transition of hepatocellular carcinoma by inhibiting YAP

https://doi.org/10.18632/oncotarget.20909

Shuo Yu, Li Jing, Xiao-Ran Yin, Min-Cong Wang, Yi-Meng Chen, Ya Guo, Ke-Jun Nan, and Li-Li Han
99757-99771
Abstract  |  PDF  |  Full Text  |  How to cite

Identification of hub genes related to siliconeinduced immune response in rats

https://doi.org/10.18632/oncotarget.21546

Xiaolu Huang, Yiwen Zhou, Wenhui Liu, Haizhou Li, Xiao Liang, Rui Jin, Hengyu Du, Jizhou He, Bangda Chai, Ran Duan, and Qingfeng Li
99772-99783
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Mesenchymal stem cells inhibit T cell activation by releasing TGFβ1 from TGFβ1/GARP complex

https://doi.org/10.18632/oncotarget.21549

Jian Niu, Wang Yue, Zhu Le-Le, Liu Bin, and Xin Hu
99784-99800
Abstract  |  PDF  |  Full Text  |  How to cite

Tumorassociated macrophages promote tumor metastasis via the TGFβ/SOX9 axis in nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.21068

Shuai Zhang, Dehai Che, Fang Yang, Chunling Chi, Hongxue Meng, Jing Shen, Li Qi, Fang Liu, Liyan Lv, Yue Li, Qingwei Meng, Junning Liu, Lihua Shang, and Yan Yu
99801-99815
Abstract  |  PDF  |  Full Text  |  How to cite

R383C mutation of human CDC20 results in idiopathic nonobstructive azoospermia

https://doi.org/10.18632/oncotarget.21071

Lingwei Li, Liqing Fan, Nanni Peng, Lihua Yang, Lisha Mou, and Weiren Huang
99816-99824
Abstract  |  PDF  |  Full Text  |  How to cite

Saikosaponind a calcium mobilizing agent sensitizes chemoresistant ovarian cancer cells to cisplatininduced apoptosis by facilitating mitochondrial fission and G2/M arrest

https://doi.org/10.18632/oncotarget.21076

Hideaki Tsuyoshi, Vincent Kam Wai Wong, Yu Han, Makoto Orisaka, Yoshio Yoshida, and Benjamin K. Tsang
99825-99840
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Extracellular vesicles from KSHVinfected endothelial cells activate the complement system

https://doi.org/10.18632/oncotarget.21668

Hyungtaek Jeon, Seung-Min Yoo, Hyo Sun Choi, Ji Young Mun, Hee-Gyoo Kang, Jiyeong Lee, Jinsung Park, Shou-Jiang Gao, and Myung-Shin Lee
99841-99860
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Highsensitivity modified Glasgow prognostic score HSmGPS Is superior to the mGPS in esophageal cancer patients treated with chemoradiotherapy

https://doi.org/10.18632/oncotarget.21734

Peng Chen, Min Fang, Qiuyan Wan, Xuebang Zhang, Tao Song, and Shixiu Wu
99861-99870
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR4835p promotes IGFII transcription and is associated with poor prognosis of hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.21737

Shaohui Tang, Yanfang Chen, Shufen Feng, Tingzhuang Yi, Xuyou Liu, Qiang Li, Zhilong Liu, Cuiping Zhu, Jianjun Hu, Xi Yu, Min Wang, Guoli Cao, Hui Tang, Caiqun Bie, Feng Ma, Huijun Tang, Gang Du, and Jianwei Huang
99871-99888
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ALVJ infection induces chicken monocyte death accompanied with the production of IL1β and IL18

https://doi.org/10.18632/oncotarget.21906

Manman Dai, Min Feng, Tingting Xie, Yuanfang Li, Zhuohao Ruan, Meiqing Shi, Ming Liao, and Xiquan Zhang
99889-99900
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PD1/PDL1 interaction upregulates MDR1/Pgp expression in breast cancer cells via PI3K/AKT and MAPK/ERK pathways

https://doi.org/10.18632/oncotarget.21914

Shengwei Liu, Shuang Chen, Weiguang Yuan, Hongyan Wang, Kewang Chen, Dianjun Li, and Dalin Li
99901-99912
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Functional profiling of microtumors to identify cancer associated fibroblastderived drug targets

https://doi.org/10.18632/oncotarget.21915

Shane R. Horman, Jeremy To, John Lamb, Jocelyn H. Zoll, Nicole Leonetti, Buu Tu, Rita Moran, Robbin Newlin, John R. Walker, and Anthony P. Orth
99913-99930
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Antioxidant MMCC ameliorates catchup growth related metabolic dysfunction

https://doi.org/10.18632/oncotarget.21965

Liping Ju, Wenxin Tong, Miaoyan Qiu, Weili Shen, Jichao Sun, Sheng Zheng, Ying Chen, Wentao Liu, and Jingyan Tian
99931-99939
Abstract  |  PDF  |  Full Text  |  How to cite

Construction of a model predicting the risk of tube feeding intolerance after gastrectomy for gastric cancer based on 225 cases from a single Chinese center

https://doi.org/10.18632/oncotarget.21966

Wu Xiaoyong, Li Xuzhao, Yu Deliang, Yu Pengfei, Hang Zhenning, Bai Bin, Li Zhengyan, Pang Fangning, Wang Shiqi, and Zhao Qingchuan
99940-99949
Abstract  |  PDF  |  Full Text  |  How to cite

The humanized antihuman AMHRII mAb 3C23K exerts an antitumor activity against human ovarian cancer through tumorassociated macrophages

https://doi.org/10.18632/oncotarget.21556

Houcine Bougherara, Fariba Némati, André Nicolas, Gérald Massonnet, Martine Pugnière, Charlotte Ngô, Marie-Aude Le Frère-Belda, Alexandra Leary, Jérôme Alexandre, Didier Meseure, Jean-Marc Barret, Isabelle Navarro-Teulon, André Pèlegrin, Sergio Roman-Roman, Jean-François Prost, Emmanuel Donnadieu, and Didier Decaudin
99950-99965
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Distinctive DNA mismatch repair and APC rare variants in African Americans with colorectal neoplasia

https://doi.org/10.18632/oncotarget.21557

Hassan Ashktorab, Hamed Azimi, Sudhir Varma, Payaam Tavakoli, Michael L. Nickerson, and Hassan Brim
99966-99977
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tamoxifen sensitivityrelated microRNA342 is a useful biomarker for breast cancer survival

https://doi.org/10.18632/oncotarget.21577

Jessica Young, Tsutomu Kawaguchi, Li Yan, Qianya Qi, Song Liu, and Kazuaki Takabe
99978-99989
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Salivary miRNA panel to detect HPVpositive and HPVnegative head and neck cancer patients

https://doi.org/10.18632/oncotarget.21725

Yunxia Wan, Dimitrios Vagenas, Carolina Salazar, Liz Kenny, Chris Perry, Diego Calvopiña, and Chamindie Punyadeera
99990-100001
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Combination therapy of exendin4 and allogenic adiposederived mesenchymal stem cell preserved renal function in a chronic kidney disease and sepsis syndrome setting in rats

https://doi.org/10.18632/oncotarget.21727

Chih-Hung Chen, Ben-Chung Cheng, Kuan-Hung Chen, Pei-Lin Shao, Pei-Hsun Sung, Hsin-Ju Chiang, Chih-Chao Yang, Kun-Chen Lin, Cheuk-Kwan Sun, Jiunn-Jye Sheu, Hsueh-Wen Chang, Mel S. Lee, and Hon-Kan Yip
100002-100020
Abstract  |  PDF  |  Full Text  |  How to cite

Glipizide sensitizes lung cancer cells to TRAILinduced apoptosis via Akt/mTOR/autophagy pathways

https://doi.org/10.18632/oncotarget.21754

Uddin MD. Nazim, Ji-Hong Moon, You-Jin Lee, Jae-Won Seol, and Sang-Youel Park
100021-100033
Abstract  |  PDF  |  Full Text  |  How to cite

Apelin protects against myocardial ischemic injury by inhibiting dynaminrelated protein 1

https://doi.org/10.18632/oncotarget.21777

Wei Xu, Hongwei Yu, Ruixue Ma, Lina Ma, Qiushuang Liu, Huitong Shan, Chengyu Wu, Rong Zhang, Yuhong Zhou, and Hongli Shan
100034-100044
Abstract  |  PDF  |  Full Text  |  How to cite

Low concentration of formononetin promotes proliferation of estrogen receptorpositive cells through an ERαmiR375PTENERK1/2bcl2 pathway

https://doi.org/10.18632/oncotarget.21923

Yan-Hong Guo, Feng-Yan Tang, Yong Wang, Wen-Jun Huang, Jing Tian, Hui-Ling Lu, Min Xin, and Jian Chen
100045-100055
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Survival outcomes of double and triplesequential targeted therapy in patients with metastatic renal cell carcinoma: a retrospective comparison

https://doi.org/10.18632/oncotarget.21926

Sung Han Kim, Yoon Seok Suh, Jung Kwon Kim, Jae Young Joung, Ho Kyung Seo, Kang Hyun Lee, and Jinsoo Chung
100056-100065
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Proteome profiling of clear cell renal cell carcinoma in von HippelLindau patients highlights upregulation of XaaPro aminopeptidase1 an antiproliferative and antimigratory exoprotease

https://doi.org/10.18632/oncotarget.21929

Vanessa Drendel, Bianca Heckelmann, Chia-Yi Chen, Juliane Weisser, Guadalupe Espadas, Christoph Schell, Eduard Sabido, Martin Werner, Cordula A. Jilg, and Oliver Schilling
100066-100078
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Associations between HVEM/LIGHT/BTLA/CD160 polymorphisms and the occurrence of antibodymediate rejection in renal transplant recipients

https://doi.org/10.18632/oncotarget.21941

Zijie Wang, Ke Wang, Haiwei Yang, Zhijian Han, Jun Tao, Hao Chen, Yuqiu Ge, Miao Guo, Chuanjian Suo, Ji-Fu Wei, Ruoyun Tan, and Min Gu
100079-100094
Abstract  |  PDF  |  Full Text  |  How to cite

Identification of potential metabolic biomarkers of cerebrospinal fluids that differentiate tuberculous meningitis from other types of meningitis by a metabolomics study

https://doi.org/10.18632/oncotarget.21942

Yi-Ning Dai, Hai-Jun Huang, Wen-Yuan Song, Yong-Xi Tong, Dan-Hong Yang, Ming-Shan Wang, Yi-Cheng Huang, Mei-Juan Chen, Jia-Jie Zhang, Ze-Ze Ren, Wei Zheng, and Hong-Ying Pan
100095-100112
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Phenformin has antitumorigenic effects in human ovarian cancer cells and in an orthotopic mouse model of serous ovarian cancer

https://doi.org/10.18632/oncotarget.22012

Amanda L. Jackson, Wenchuan Sun, Joshua Kilgore, Hui Guo, Ziwei Fang, Yajie Yin, Hannah M. Jones, Timothy P. Gilliam, Chunxiao Zhou, and Victoria L. Bae-Jump
100113-100127
Abstract  |  PDF  |  Full Text  |  How to cite

The aldehyde group of gossypol induces mitochondrial apoptosis via ROSSIRT1p53PUMA pathway in male germline stem cell

https://doi.org/10.18632/oncotarget.22044

Xin He, Chongyang Wu, Yanhua Cui, Haijing Zhu, Zhiming Gao, Bo Li, Jinlian Hua, and Baoyu Zhao
100128-100140
Abstract  |  PDF  |  Full Text  |  How to cite

Digenic mutations on SCAP and AGXT2 predispose to premature myocardial infarction

https://doi.org/10.18632/oncotarget.22045

Yuanfeng Gao, Chongyou Lee, Junxian Song, Sufang Li, Yuxia Cui, Yongzhen Liu, Jie Wang, Fengmin Lu, and Hong Chen
100141-100149
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genetic predisposition to ischaemic stroke by RAGE and HMGB1 gene variants in Chinese Han population

https://doi.org/10.18632/oncotarget.22112

You Li, Jing Zhu, Linfa Chen, Weidong Hu, Mengxu Wang, Shengnan Li, Xuefeng Gu, Hua Tao, Bin Zhao, Guoda Ma, and Keshen Li
100150-100164
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Associations of tumor regression grade with outcomes in patients with locally advanced rectal cancer treated with preoperative twoweek course of radiotherapy

https://doi.org/10.18632/oncotarget.22118

Yong-Heng Li, Jin-Luan Li, Xiang-Gao Zhu, Jun-Yan He, Li-Mei Lin, Xiao-Yi Lin, Li-Rui Tang, and Yong Cai
100165-100175
Abstract  |  PDF  |  Full Text  |  How to cite

Decreased expression of interferoninduced protein 2 IFIT2 by Wnt/βcatenin signaling confers antiapoptotic properties to colorectal cancer cells

https://doi.org/10.18632/oncotarget.22122

Tomoyuki Ohsugi, Kiyoshi Yamaguchi, Chi Zhu, Tsuneo Ikenoue, and Yoichi Furukawa
100176-100186
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Calcitriol induces cell senescence of kidney cancer through JMJD3 mediated histone demethylation

https://doi.org/10.18632/oncotarget.22124

Yongqing Shen, Dan Yu, Pan Qi, Xuliang Wang, Xiaoqiang Guo, and Aili Zhang
100187-100195
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Systematic analysis of the expression profile of noncoding RNAs involved in ischemia/reperfusioninduced acute kidney injury in mice using RNA sequencing

https://doi.org/10.18632/oncotarget.22130

Jun Zhou, Hongtao Chen, and Youling Fan
100196-100215
Abstract  |  PDF  |  Full Text  |  How to cite

Apigenin inhibits colonic inflammation and tumorigenesis by suppressing STAT3NFκB signaling

https://doi.org/10.18632/oncotarget.22145

Xiao-Yu Ai, Yuan Qin, Hui-Jua Liu, Zhan-Hong Cui, Meng Li, Jia-Huan Yang, Wei-Long Zhong, Yan-Rong Liu, Shuang Chen, Tao Sun, Hong-Gang Zhou, and Cheng Yang
100216-100226
Abstract  |  PDF  |  Full Text  |  How to cite

MicroRNA433 inhibits oral squamous cell carcinoma cells by targeting FAK

https://doi.org/10.18632/oncotarget.22151

Yong-Jian Wang, Zi-Feng Zhang, Shao-Hua Fan, Juan Zhuang, Qun Shan, Xin-Rui Han, Xin Wen, Meng-Qiu Li, Bin Hu, Chun-Hui Sun, Bin Qiao, Qian Tao, Dong-Mei Wu, Jun Lu, and Yuan-Lin Zheng
100227-100241
Abstract  |  PDF  |  Full Text  |  How to cite

Chondroitin sulfatases differentially regulate Wnt signaling in prostate stem cells through effects on SHP2 phosphoERK1/2 and Dickkopf Wnt signaling pathway inhibitor DKK3

https://doi.org/10.18632/oncotarget.22152

Sumit Bhattacharyya, Leo Feferman, and Joanne K. Tobacman
100242-100260
Abstract  |  PDF  |  Full Text  |  How to cite

MAPK and ERK polymorphisms are associated with PCOS risk in Chinese women

https://doi.org/10.18632/oncotarget.22153

Lingmin Hu, Yiting Zhang, Li Chen, Wei Zhou, Yong Wang, and Juan Wen
100261-100268
Abstract  |  PDF  |  Full Text  |  How to cite

Gsdma3 regulates hair follicle differentiation via Wnt5amediated noncanonical Wnt signaling pathway

https://doi.org/10.18632/oncotarget.22212

Long He, Mingxing Lei, Yizhan Xing, Yuhong Li, Chunyan Hu, Peixing Chen, Xiaohua Lian, Tian Yang, Wanqian Liu, and Li Yang
100269-100279
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The cancertestis antigen sperm protein 17 a new biomarker and immunological target in head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.22213

Christopher A. Schutt, Leonardo Mirandola, Jose A. Figueroa, Diane D. Nguyen, Joehassin Cordero, Klauss Bumm, Benjamin L. Judson, and Maurizio Chiriva-Internati
100280-100287
Abstract  |  PDF  |  Full Text  |  How to cite

Chronic kidney disease is associated with a risk of higher mortality following total knee arthroplasty in diabetic patients: a nationwide populationbased study

https://doi.org/10.18632/oncotarget.22215

Liang-Tseng Kuo, Su-Ju Lin, Chi-Lung Chen, Pei-An Yu, Wei-Hsiu Hsu, and Tien-Hsing Chen
100288-100295
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Variations in plasma concentrations of tamoxifen metabolites and the effects of genetic polymorphisms on tamoxifen metabolism in Korean patients with breast cancer

https://doi.org/10.18632/oncotarget.22220

Hye In Woo, Se Kyung Lee, Jiyoung Kim, Seok Won Kim, Jonghan Yu, Soo Youn Bae, Jeong Eon Lee, Seok Jin Nam, and Soo-Youn Lee
100296-100311
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

An antiCAPN5 intracellular antibody acts as an inhibitor of CAPN5mediated neuronal degeneration

https://doi.org/10.18632/oncotarget.22221

Yan Wang, Xiao Zhang, Zongming Song, and Feng Gu
100312-100325
Abstract  |  PDF  |  Full Text  |  How to cite

Cotargeting aurora kinase with PDL1 and PI3K abrogates immune checkpoint mediated proliferation in peripheral Tcell lymphoma: a novel therapeutic strategy

https://doi.org/10.18632/oncotarget.22222

Shariful Islam, Eric Vick, Bryan Huber, Carla Morales, Catherine Spier, Laurence Cooke, Eric Weterings, and Daruka Mahadevan
100326-100338
Abstract  |  PDF  |  Full Text  |  How to cite

Endothelialderived interleukin6 induces cancer stem cell motility by generating a chemotactic gradient towards blood vessels

https://doi.org/10.18632/oncotarget.22225

Hong Sun Kim, Yu-Chih Chen, Felipe Nör, Kristy A. Warner, April Andrews, Vivian P. Wagner, Zhaocheng Zhang, Zhixiong Zhang, Manoela D. Martins, Alexander T. Pearson, Euisik Yoon, and Jacques E. Nör
100339-100352
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Serum corin is associated with the risk of chronic heart failure

https://doi.org/10.18632/oncotarget.22227

Zongliang Yu, Xiang Lu, Weiting Xu, Mengchao Jin, Yifei Tao, and Xiang Zhou
100353-100357
Abstract  |  PDF  |  Full Text  |  How to cite

Krüppellike factor 2 suppresses human gastric tumorigenesis through inhibiting PTEN/AKT signaling

https://doi.org/10.18632/oncotarget.22229

Chunmei Wang, Liang Li, Qiuhui Duan, Qingqing Wang, and Jinlian Chen
100358-100370
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Effect of dexmedetomidine infusion for intravenous patientcontrolled analgesia on the quality of recovery after laparotomy surgery

https://doi.org/10.18632/oncotarget.22232

Juan Xin, Yabing Zhang, Leng Zhou, Fei Liu, Xiaoshuang Zhou, Bin Liu, and Qian Li
100371-100383
Abstract  |  PDF  |  Full Text  |  How to cite

Plasma proteomics reveals coagulation inflammation and metabolic shifts in Htype hypertension patients with and without acute ischemic stroke

https://doi.org/10.18632/oncotarget.22233

Feng Zhou, Lv Zhou, Tie Guo, Nianzhen Wang, Haizhen Hao, Yanhui Zhou, and Dan Yu
100384-100395
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Hydrogen sulfide attenuates chronic restrain stressinduced cognitive impairment by upreglulation of Sirt1 in hippocampus

https://doi.org/10.18632/oncotarget.22237

Xiao-Na Li, Lei Chen, Bang Luo, Xiang Li, Chun-Yan Wang, Wei Zou, Ping Zhang, Yong You, and Xiao-Qing Tang
100396-100410
Abstract  |  PDF  |  Full Text  |  How to cite

Alcohol intake aggravates adipose browning and muscle atrophy in cancerassociated cachexia

https://doi.org/10.18632/oncotarget.22243

Bo Wang, Faya Zhang, Hui Zhang, Zhixiu Wang, Yan-Nan Ma, Mei-Jun Zhu, and Min Du
100411-100420
Abstract  |  PDF  |  Full Text  |  How to cite

CDK4/6 dual inhibitor abemaciclib demonstrates compelling preclinical activity against esophageal adenocarcinoma: a novel therapeutic option for a deadly disease

https://doi.org/10.18632/oncotarget.22244

Juliann E. Kosovec, Ali H. Zaidi, Ashten N. Omstead, Daisuke Matsui, Mark J. Biedka, Erin J. Cox, Patrick T. Campbell, Robert W.W. Biederman, Ronan J. Kelly, and Blair A. Jobe
100421-100432
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Caspase4 is essential for saikosaponin ainduced apoptosis acting upstream of caspase2 and γH2AX in colon cancer cells

https://doi.org/10.18632/oncotarget.22247

Su Jin Kang, Young Joon Lee, Sung Gu Kang, Soyoung Cho, Wonsuck Yoon, Ji Hong Lim, Sang-Hyun Min, Tae Ho Lee, and Byeong Mo Kim
100433-100448
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Meta-Analysis

The impact of metformin use on survival in prostate cancer: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.22117

Yao Xiao, Lei Zheng, Zubing Mei, Changbao Xu, Changwei Liu, Xiaohan Chu, and Bin Hao
100449-100458
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

HTR3A and HTR3E gene polymorphisms and diarrhea predominant irritable bowel syndrome risk: evidence from a metaanalysis

https://doi.org/10.18632/oncotarget.19682

Tangming Guan, Ting Li, Weiming Cai, Dong Huang, Peipei Ouyang, Yan Wang, Huayan Chen, Kefeng Wu, and Xiaoli Ma
100459-100468
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Comparison of efficacy between brachytherapy and penectomy in patients with penile cancer: a metaanalysis

https://doi.org/10.18632/oncotarget.18761

Xiheng Hu, Jianghai Huang, Sailan Wen, Jun Fu, and Minfeng Chen
100469-100477
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinicopathological and prognostic significance of HMGA2 overexpression in gastric cancer: a metaanalysis

https://doi.org/10.18632/oncotarget.19001

Jingyi Zhu, Hailong Wang, Shuangnian Xu, and Yingxue Hao
100478-100489
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prognostic role of long noncoding RNA ZFAS1 in cancer patients: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.19162

Tian Lan, Xiong Lan, Guangcai Li, Zhen Zheng, Minghua Zhang, and Faxiang Qin
100490-100498
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prognostic role of long noncoding RNA TUG1 expression in various cancers: a metaanalysis

https://doi.org/10.18632/oncotarget.20037

Yongping Zhou, Yuxuan Lu, Runmin Li, Nana Yan, Xiding Li, and Tu Dai
100499-100507
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

What is the best combination treatment with transarterial chemoembolization of unresectable hepatocellular carcinoma a systematic review and network metaanalysis

https://doi.org/10.18632/oncotarget.20119

Hui Xie, Haipeng Yu, Shengtao Tian, Xueling Yang, Ximing Wang, Zhao Yang, Huaming Wang, and Zhi Guo
100508-100523
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Effects of levosimendan on mortality in patients with septic shock: systematic review with metaanalysis and trial sequential analysis

https://doi.org/10.18632/oncotarget.20123

Benji Wang, Rujie Chen, Xianyang Guo, Wenwu Zhang, Jianjian Hu, Yuqiang Gong, and Bihuan Cheng
100524-100532
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Long noncoding RNAs for osteosarcoma in the mouse: a metaanalysis

https://doi.org/10.18632/oncotarget.20128

Shaopu Hu, Junli Chang, Yimian Li, Wenyi Wang, Edward C. Zou, Mengyao Guo, Qi Shi, Yongjun Wang, and Yanping Yang
100533-100544
Abstract  |  PDF  |  Full Text  |  How to cite

Increased DCLK1 correlates with the malignant status and poor outcome in malignant tumors: a metaanalysis

https://doi.org/10.18632/oncotarget.20129

Wenhua Shi, Fangwei Li, Shaojun Li, Jian Wang, Qingting Wang, Xin Yan, Qianqian Zhang, Limin Chai, and Manxiang Li
100545-100557
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Association of PPARG rs 1801282 C>G polymorphism with risk of colorectal cancer: from a casecontrol study to a metaanalysis

https://doi.org/10.18632/oncotarget.20138

Jiakai Jiang, Zhiqiang Xie, JunYing Guo, Yafeng Wang, Chao Liu, Sheng Zhang, Weifeng Tang, and Yu Chen
100558-100569
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Smoking and risk of cholangiocarcinoma: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.20141

Yuenan Huang, Liuping You, Weimin Xie, Li Ning, and Jinghe Lang
100570-100581
Abstract  |  PDF  |  Full Text  |  How to cite

Exogenous melatonin in the treatment of pain: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.21504

Chaojuan Zhu, Yunyun Xu, Yonghong Duan, Wei Li, Li Zhang, Yang Huang, Wei Zhao, Yutong Wang, Junjie Li, Ting Feng, Xiaomei Li, Xuehui Hu, and Wen Yin
100582-100592
Abstract  |  PDF  |  Full Text  |  How to cite

Comprehensive assessment of association between TLR4 gene polymorphisms and cancer risk: a systematic metaanalysis

https://doi.org/10.18632/oncotarget.21543

Lu Ding, Qifeng Jiang, Guang Li, Jia Shen, Jiayin Du, Xiaochen Lu, and Xingliang Xiong
100593-100602
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Potassium measurements and risk of type 2 diabetes: a doseresponse metaanalysis of prospective cohort studies

https://doi.org/10.18632/oncotarget.21823

Yang Peng, Guo-Chao Zhong, Qiao Mi, Kejia Li, Ao Wang, Ling Li, Hua Liu, and Gangyi Yang
100603-100613
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Significance of Ki67 in nonmuscle invasive bladder cancer patients: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.21899

Kyungtae Ko, Chang Wook Jeong, Cheol Kwak, Hyeon Hoe Kim, and Ja Hyeon Ku
100614-100630
Abstract  |  PDF  |  Full Text  |  How to cite

Diagnostic prediction of urinary [TIMP2] x [IGFBP7] for acute kidney injury: A metaanalysis exploring detection time and cutoff levels

https://doi.org/10.18632/oncotarget.21903

Zhenzhu Song, Zhongchao Ma, Kai Qu, Sinan Liu, Wenquan Niu, and Ting Lin
100631-100639
Abstract  |  PDF  |  Full Text  |  How to cite

Effect of hyperthermic intrathoracic chemotherapy on the malignant pleural mesothelioma: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.22062

Zi-Yi Zhao, Sha-Sha Zhao, Meng Ren, Zi-Ling Liu, Zhi Li, and Lei Yang
100640-100647
Abstract  |  PDF  |  Full Text  |  How to cite

Evaluation of the NMP22 BladderChek test for detecting bladder cancer: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.22065

Zijie Wang, Hongliang Que, Chuanjian Suo, Zhijian Han, Jun Tao, Zhengkai Huang, Xiaobin Ju, Ruoyun Tan, and Min Gu
100648-100656
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The efficacy and safety of different pharmacological interventions for patients with advanced biliary tract cancer: A network metaanalysis

https://doi.org/10.18632/oncotarget.20445

Xin-Fang Sun, Zhi-Kuan He, Jin-Ping Sun, Quan-Xing Ge, and Er-Dong Shen
100657-100667
Abstract  |  PDF  |  Full Text  |  How to cite

Network metaanalysis of the efficacy of firstline chemotherapy regimens in patients with advanced colorectal cancer

https://doi.org/10.18632/oncotarget.22177

Dong-Mei Wu, Yong-Jian Wang, Shao-Hua Fan, Juan Zhuang, Zi-Feng Zhang, Qun Shan, Xin-Rui Han, Xin Wen, Meng-Qiu Li, Bin Hu, Chun-Hui Sun, Ya-Xing Bao, Hai-Juan Xiao, Lin Yang, Jun Lu, and Yuan-Lin Zheng
100668-100677
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinical Research Papers

Characterization of the urinary microbiota of elderly women and the effects of type 2 diabetes and urinary tract infections on the microbiota

https://doi.org/10.18632/oncotarget.21126

Fengping Liu, Zongxin Ling, Yonghong Xiao, Qing Yang, Li Zheng, Ping Jiang, Lanjuan Li, and Wei Wang
100678-100690
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The protective effect of PFTα on alcoholinduced osteonecrosis of the femoral head

https://doi.org/10.18632/oncotarget.19160

Yi-Xuan Chen, Dao-Yu Zhu, Jun-Hui Yin, Wen-Jing Yin, Yue-Lei Zhang, Hao Ding, Xiao-Wei Yu, Jiong Mei, You-Shui Gao, and Chang-Qing Zhang
100691-100707
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Outcome of oligoprogressing metastatic renal cell carcinoma patients treated with locoregional therapy: a multicenter retrospective analysis

https://doi.org/10.18632/oncotarget.20022

Daniele Santini, Raffaele Ratta, Francesco Pantano, Delia De Lisi, Marco Maruzzo, Luca Galli, Elisa Biasco, Azzurra Farnesi, Sebastiano Buti, Cora Nanette Sternberg, Linda Cerbone, Giuseppe Di Lorenzo, Silvia Spoto, Michelle Sterpi, Ugo De Giorgi, Rossana Berardi, Mariangela Torniai, Andrea Camerini, Francesco Massari, Giuseppe Procopio, and Giuseppe Tonini
100708-100716
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Congenital heart defects of fetus after maternal exposure to organic and inorganic environmental factors: a cohort study

https://doi.org/10.18632/oncotarget.20110

Wei Gong, Qianhong Liang, Dongming Zheng, Risheng Zhong, Yunjie Wen, and Xiaodan Wang
100717-100723
Abstract  |  PDF  |  Full Text  |  How to cite

Optimal treatment strategies for clinically suspicious lateral pelvic lymph node metastasis in rectal cancer

https://doi.org/10.18632/oncotarget.20121

Hye Jin Kim, Gyu-Seog Choi, Jun Seok Park, Soo Yeun Park, Seung Hyun Cho, Soo Jung Lee, Byung Woog Kang, and Jong Gwang Kim
100724-100733
Abstract  |  PDF  |  Full Text  |  How to cite

Efficacy and safety of apatinib combined with transarterial chemoembolization for hepatocellular carcinoma with portal venous tumor thrombus: a retrospective study

https://doi.org/10.18632/oncotarget.20140

Changfu Liu, Wenge Xing, Tongguo Si, Haipeng Yu, and Zhi Guo
100734-100745
Abstract  |  PDF  |  Full Text  |  How to cite

Preoperative radiotherapy for patients with rectal cancer: a risk factor for nonreversal of ileostomy caused by stenosis or stiffness proximal to colorectal anastomosis

https://doi.org/10.18632/oncotarget.20602

Hongbo Zhu, Bingjun Bai, Lina Shan, Xiaowei Wang, Min Chen, Weifang Mao, and Xuefeng Huang
100746-100753
Abstract  |  PDF  |  Full Text  |  How to cite

Clinicopathological and genetic characteristics of pulmonary large cell carcinoma under 2015 WHO classification: a pilot study

https://doi.org/10.18632/oncotarget.21736

Renwang Liu, Jinghao Liu, Tao Shi, Xiongfei Li, Dian Ren, Gang Chen, Ying Li, Hongyu Liu, Song Xu, and Jun Chen
100754-100763
Abstract  |  PDF  |  Full Text  |  How to cite

Neoadjuvant chemotherapy with different dose regimens of docetaxel cisplatin and fluorouracil TPF for locoregionally advanced nasopharyngeal carcinoma: a retrospective study

https://doi.org/10.18632/oncotarget.21992

Ting Jin, Qun Zhang, Feng Jiang, Wei-Feng Qin, Qi-Feng Jin, Cai-Neng Cao, Yong-Feng Piao, Xing-Lai Feng, Wei Luo, and Xiao-Zhong Chen
100764-100772
Abstract  |  PDF  |  Full Text  |  How to cite

Ovarian stimulated cycle: not a better alternative for women without ovulation disorder in intrauterine insemination

https://doi.org/10.18632/oncotarget.22052

Kemei Zhang, Yinjiao Shi, Ensheng Wang, Li Wang, Qingbo Hu, Yibo Dai, Haiyan Xu, Jiaou Zhang, Ping Jin, Xueqin Chen, and Jing Shu
100773-100780
Abstract  |  PDF  |  Full Text  |  How to cite

Reviews

Tumorderived exosomes in colorectal cancer progression and their clinical applications

https://doi.org/10.18632/oncotarget.20117

Jianbiao Zhou, Xiao-Lan Li, Zhi-Rong Chen, and Wee-Joo Chng
100781-100790
Abstract  |  PDF  |  Full Text  |  How to cite

Does primary tumor location impact the prognosis of colorectal liver metastases patients after microwave ablation Lessons from 10 years’ experience

https://doi.org/10.18632/oncotarget.18764

Fubo Zhou, Xiaoling Yu, Ping Liang, Zhiyu Han, Zhigang Cheng, Jie Yu, Fangyi Liu, and Yi Hu
100791-100800
Abstract  |  PDF  |  Full Text  |  How to cite

Comparison of crossplatform technologies for EGFR T790M testing in patients with nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.19007

Xuefei Li, and Caicun Zhou
100801-100818
Abstract  |  PDF  |  Full Text  |  How to cite

miRNA and lncRNA as biomarkers in cholangiocarcinomaCCA

https://doi.org/10.18632/oncotarget.19044

Bo Zheng, Seogsong Jeong, Yanjing Zhu, Lei Chen, and Qiang Xia
100819-100830
Abstract  |  PDF  |  Full Text  |  How to cite

Circulating biomarkers in osteosarcoma: new translational tools for diagnosis and treatment

https://doi.org/10.18632/oncotarget.19852

Lavinia Raimondi, Angela De Luca, Viviana Costa, Nicola Amodio, Valeria Carina, Daniele Bellavia, Pierfrancesco Tassone, Stefania Pagani, Milena Fini, Riccardo Alessandro, and Gianluca Giavaresi
100831-100851
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Recent advances on uric acid transporters

https://doi.org/10.18632/oncotarget.20135

Liuqing Xu, Yingfeng Shi, Shougang Zhuang, and Na Liu
100852-100862
Abstract  |  PDF  |  Full Text  |  How to cite

Challenges and future of biomarker tests in the era of precision oncology: Can we rely on immunohistochemistry IHC or fluorescence in situ hybridization FISH to select the optimal patients for matched therapy

https://doi.org/10.18632/oncotarget.19809

Young Kwang Chae, Ayush Arya, Lauren Chiec, Hiral Shah, Ari Rosenberg, Sandip Patel, Kirtee Raparia, Jaehyuk Choi, Derek A. Wainwright, Victoria Villaflor, Massimo Cristofanilli, and Francis Giles
100863-100898
Abstract  |  PDF  |  Full Text  |  How to cite

The role of microbiota in the pathogenesis of schizophrenia and major depressive disorder and the possibility of targeting microbiota as a treatment option

https://doi.org/10.18632/oncotarget.21284

Fengli Lv, Suling Chen, Lina Wang, Ronghuan Jiang, Hongjun Tian, Jie Li, Yudong Yao, and Chuanjun Zhuo
100899-100907
Abstract  |  PDF  |  Full Text  |  How to cite

Venombased peptide therapy: insights into anticancer mechanism

https://doi.org/10.18632/oncotarget.21740

Rui Ma, Ravikiran Mahadevappa, and Hang Fai Kwok
100908-100930
Abstract  |  PDF  |  Full Text  |  How to cite

A molecular view of the radioresistance of gliomas

https://doi.org/10.18632/oncotarget.21753

Xuetao Han, Xiaoying Xue, Huandi Zhou, and Ge Zhang
100931-100941
Abstract  |  PDF  |  Full Text  |  How to cite

Case Reports

A rare case of esophageal metastasis from pancreatic ductal adenocarcinoma: a case report and literature review

https://doi.org/10.18632/oncotarget.18458

Lauren M. Rosati, Megan N. Kummerlowe, Justin Poling, Amy Hacker-Prietz, Amol K. Narang, Eun J. Shin, Dung T. Le, Elliot K. Fishman, Ralph H. Hruban, Stephen C. Yang, Matthew J. Weiss, and Joseph M. Herman
100942-100950
Abstract  |  PDF  |  Full Text  |  How to cite

Meeting Reports

Results and prospects of development of new polyphenolic drugs for cancer patients

https://doi.org/10.18632/oncotarget.22307

Vladimir N. Anisimov, Stig Larsen, Stig Lofberg, Irina A. Baldueva, Anastasia V. Malek, Tea Kirkegaard Nielsen, Elena I. Fedoros, Irina V. Perminova, Evgeny Yu. Drobyshev, Vladimir N. Bykov, Andrey V. Panchenko, Alexander M. Scherbakov, and Alexey M. Belyaev
100951-100956
Abstract  |  PDF  |  Full Text  |  How to cite

Corrections

Correction: Prognostic and diagnostic significance of lncRNAs expression in cervical cancer: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.22570

Shuqi Chi, Lina Shen, Teng Hua, Shuangge Liu, Guobing Zhuang, Xiaoxiao Wang, Xing Zhou, Guozhen Wang, and Hongbo Wang
100957-100957
Correction  |  PDF  |  How to cite


Copyright © 2026 Rapamycin Press LLC dba Impact Journals
Oncotarget ® is a registered trademark of Rapamycin Press LLC
Impact Journals ® is a registered trademark of Rapamycin Press LLC
RAPAMYCIN PRESS ® is a registered trademark of Rapamycin Press LLC
By using our site you are giving us permission to use cookies. This website collects cookies to deliver a better user experience, and to analyze our website traffic and performance. Personal data is not collected.