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The cover for issue 31 of Oncotarget features Figure 7, "Model for effects of AURKA inhibition on NHEJ in ovarian carcinoma cells and combination with PARP inhibitors," from Do, et al.

Table of Contents

News

Unveiling kaposi sarcoma viral antigens

https://doi.org/10.18632/oncotarget.19106

Jaeyeun Lee, John G. Kosowicz, and Richard F. Ambinder
50325-50326
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Editorial

Multistory Parkin

https://doi.org/10.18632/oncotarget.18318

Aitor Martinez, Ugo Mayor, and Michael J. Clague
50327-50328
Abstract  |  PDF  |  How to cite

NFκBmediated astrocyte dysfunction initiates neurodegeneration

https://doi.org/10.18632/oncotarget.18320

Michael Lattke, Stephanie N. Reichel, and Bernd Baumann
50329-50330
Abstract  |  PDF  |  How to cite

Immunosuppression by viral N proteins

https://doi.org/10.18632/oncotarget.18597

Jidang Chen, and Hinh Ly
50331-50332
Abstract  |  PDF  |  How to cite

Targeting APP/AICD in Down syndrome

https://doi.org/10.18632/oncotarget.18860

Sandra Guidi, Fiorenza Stagni, and Renata Bartesaghi
50333-50334
Abstract  |  PDF  |  How to cite

Reversibility of Aβ oligomer neurotoxicity

https://doi.org/10.18632/oncotarget.19083

Wataru Araki
50335-50336
Abstract  |  PDF  |  How to cite

Research Perspectives

PPARs as determinants of the estrogen receptor lineage: use of synthetic lethality for the treatment of estrogen receptornegative breast cancer

https://doi.org/10.18632/oncotarget.17302

Robert I. Glazer, and Levy Kopelovich
50337-50341
Abstract  |  PDF  |  Full Text  |  How to cite

Priority Research Papers

Restoration of immune surface molecules in Kaposi sarcomaassociated herpes virus infected cells by lenalidomide and pomalidomide

https://doi.org/10.18632/oncotarget.17960

David A. Davis, Suraj Mishra, Holda A. Anagho, Ashley I. Aisabor, Prabha Shrestha, Victoria Wang, Yuki Takamatsu, Kenji Maeda, Hiroaki Mitsuya, Jerome B. Zeldis, and Robert Yarchoan
50342-50358
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Modulation of estrogen related receptor alpha activity by the kinesin KIF17

https://doi.org/10.18632/oncotarget.18104

AM Pramodh Bandara Seneviratne, Zeynep Turan, Aurelie Hermant, Patrick Lecine, William O. Smith, Jean-Paul Borg, Fanny Jaulin, and Geri Kreitzer
50359-50375
Abstract  |  PDF  |  Full Text  |  How to cite

Aurora A kinase regulates nonhomologous endjoining and polyADPribose polymerase function in ovarian carcinoma cells

https://doi.org/10.18632/oncotarget.18970

Thuy-Vy Do, Jeff Hirst, Stephen Hyter, Katherine F. Roby, and Andrew K. Godwin
50376-50392
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Gerotarget (Focus on Aging)

Diagnostic performance of gait speed G8 and G8 modified indices to screen for vulnerability in older cancer patients: the prospective PFEC cohort study

https://doi.org/10.18632/oncotarget.17361

Frederic Pamoukdjian, Florence Canoui-Poitrine, Coralie Longelin-Lombard, Thomas Aparicio, Nathalie Ganne, Philippe Wind, Claudia Martinez-Tapia, Etienne Audureau, Georges Sebbane, Laurent Zelek, and Elena Paillaud
50393-50402
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers: Pathology

PhosphoAXL is widely expressed in glioblastoma and associated with significant shorter overall survival

https://doi.org/10.18632/oncotarget.18468

Julia Onken, Peter Vajkoczy, Robert Torka, Claudia Hempt, Victor Patsouris, Frank L. Heppner, and Josefine Radke
50403-50414
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Immunology

A single nucleotide polymorphism in the interferonγ gene IFNG +874 T/A is associated with susceptibility to tuberculosis

https://doi.org/10.18632/oncotarget.17304

Zhang Wei, Shen Wenhao, Mi Yuanyuan, Li Yang, Zhou Daming, Xian Jiangchun, and Jiang Jijun
50415-50429
Abstract  |  PDF  |  Full Text  |  How to cite

Histopathological findings of renal tissue induced by oxidative stress due to different concentrations of fluoride

https://doi.org/10.18632/oncotarget.17365

Qin Luo, Hengmin Cui, Huidan Deng, Ping Kuang, Huan Liu, Yujiao Lu, Jing Fang, Zhicai Zuo, Junliang Deng, Yinglun Li, Xun Wang, and Ling Zhao
50430-50446
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers

Prevention of colitisassociated cancer by selective targeting of immunoproteasome subunit LMP7

https://doi.org/10.18632/oncotarget.14579

Niyati Vachharajani, Thorsten Joeris, Maik Luu, Sabrina Hartmann, Sabine Pautz, Elena Jenike, Georgios Pantazis, Immo Prinz, Markus J. Hofer, Ulrich Steinhoff, and Alexander Visekruna
50447-50459
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Overexpression of C16orf74 is involved in aggressive pancreatic cancers

https://doi.org/10.18632/oncotarget.10912

Toru Nakamura, Toyomasa Katagiri, Shoki Sato, Toshihiro Kushibiki, Koji Hontani, Takahiro Tsuchikawa, Satoshi Hirano, and Yusuke Nakamura
50460-50475
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Inhibition of PI3K/Akt/mTOR signaling in PI3KR2overexpressing colon cancer stem cells reduces tumor growth due to apoptosis

https://doi.org/10.18632/oncotarget.9919

Sugong Chen, Robert C. Fisher, Steven Signs, L. Alex Molina, Anitha K. Shenoy, Maria-Cecilia Lopez, Henry V. Baker, John M. Koomen, Yi Chen, Haley Gittleman, Jill Barnholtz-Sloan, Annamarie Berg, Henry D. Appelman, and Emina H. Huang
50476-50488
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A comprehensively characterized cell line panel highly representative of clinical ovarian highgrade serous carcinomas

https://doi.org/10.18632/oncotarget.9929

Kelsie L. Thu, Mahboubeh Papari-Zareei, Victor Stastny, Kai Song, Michael Peyton, Victor D. Martinez, Yu-An Zhang, Isabel B. Castro, Marileila Varella-Garcia, Hanquan Liang, Chao Xing, Ralf Kittler, Sara Milchgrub, Diego H. Castrillon, Heather L. Davidson, C Patrick Reynolds, Wan L. Lam, Jayanthi Lea, and Adi F. Gazdar
50489-50499
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The establishment of a growthcontrollable orthotopic bladder cancer model through the downregulation of cmyc expression

https://doi.org/10.18632/oncotarget.10784

Ho Kyung Seo, Seung-Phil Shin, Na-Rae Jung, Whi-An Kwon, Kyung-Chae Jeong, and Sang-Jin Lee
50500-50509
Abstract  |  PDF  |  Full Text  |  How to cite

Methylation of HPV and a tumor suppressor gene reveals anal cancer and precursor lesions

https://doi.org/10.18632/oncotarget.17984

Attila T. Lorincz, Mayura Nathan, Caroline Reuter, Rhian Warman, Mohamed A. Thaha, Michael Sheaff, Natasa Vasiljevic, Amar Ahmad, Jack Cuzick, and Peter Sasieni
50510-50520
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Selective compounds enhance osteoblastic activity by targeting HECT domain of ubiquitin ligase Smurf1

https://doi.org/10.18632/oncotarget.10648

Yuan Zhang, Cheng Wang, Yu Cao, Yongqing Gu, and Lingqiang Zhang
50521-50533
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A molecular pathology method for sequential fluorescence in situ hybridization for multigene analysis at the singlecell level

https://doi.org/10.18632/oncotarget.10245

Linping Hu, Xiuxiu Yin, Jiangman Sun, Anders Zetterberg, Weimin Miao, and Tao Cheng
50534-50541
Abstract  |  PDF  |  Full Text  |  How to cite

Metformin requires 4EBPs to induce apoptosis and repress translation of Mcl1 in hepatocellular carcinoma cells

https://doi.org/10.18632/oncotarget.10671

Mamatha Bhat, Akiko Yanagiya, Tyson Graber, Nataliya Razumilava, Steve Bronk, Domenick Zammit, Yunhao Zhao, Chadi Zakaria, Peter Metrakos, Michael Pollak, Nahum Sonenberg, Gregory Gores, Maritza Jaramillo, Masahiro Morita, and Tommy Alain
50542-50556
Abstract  |  PDF  |  Full Text  |  How to cite

Troy is expressed in human stomach mucosa and a novel putative prognostic marker of intestinal type gastric cancer

https://doi.org/10.18632/oncotarget.10672

Franziska Wilhelm, Christine Böger, Sandra Krüger, Hans-Michael Behrens, and Christoph Röcken
50557-50569
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Dimerization of EGFR and HER2 induces breast cancer cell motility through STAT1dependent ACTA2 induction

https://doi.org/10.18632/oncotarget.10843

Myeongjin Jeon, Daeun You, Soo Youn Bae, Seok Won Kim, Seok Jin Nam, Hyeon Ho Kim, Sangmin Kim, and Jeong Eon Lee
50570-50581
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

C/EBPδ positively regulates MDSC expansion and endothelial VEGFR2 expression in tumor development

https://doi.org/10.18632/oncotarget.16410

Yongfen Min, Jingdong Li, Peng Qu, and Charles P. Lin
50582-50593
Abstract  |  PDF  |  Full Text  |  How to cite

Identification of KANSARL as the first cancer predisposition fusion gene specific to the population of European ancestry origin

https://doi.org/10.18632/oncotarget.16385

Jeff Xiwu Zhou, Xiaoyan Yang, Shunbin Ning, Ling Wang, Kesheng Wang, Yanbin Zhang, Fenghua Yuan, Fengli Li, David D. Zhuo, Liren Tang, and Degen Zhuo
50594-50607
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MGMT and CALCA promoter methylation are associated with poor prognosis in testicular germ cell tumor patients

https://doi.org/10.18632/oncotarget.11167

Camila Maria da Silva Martinelli, André van Helvoort Lengert, Flavio Mavignier Cárcano, Eduardo Caetano Albino Silva, Mariana Brait, Luiz Fernando Lopes, and Daniel Onofre Vidal
50608-50617
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Experimental study of brachial plexus and vessel compression: evaluation of combined central and peripheral electrodiagnostic approach

https://doi.org/10.18632/oncotarget.16817

Chaoqun Yang, Jianguang Xu, Jie Chen, Shulin Li, Yu Cao, Yi Zhu, and Lei Xu
50618-50628
Abstract  |  PDF  |  Full Text  |  How to cite

Decreased calpain activity in chronic myeloid leukemia impairs apoptosis by increasing survivin in myeloid progenitors and xiap1 in differentiating granulocytes

https://doi.org/10.18632/oncotarget.16884

Weiqi Huang, Ling Bei, Elizabeth E. Hjort, and Elizabeth A. Eklund
50629-50641
Abstract  |  PDF  |  Full Text  |  How to cite

Upregulation of microRNA125b by GCSF promotes metastasis in colorectal cancer

https://doi.org/10.18632/oncotarget.16892

Xinghua Zhang, Xiao Ma, Huaying An, Changqing Xu, Wenjo Cao, Wei Yuan, and Jie Ma
50642-50654
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Usp5 functions as an oncogene for stimulating tumorigenesis in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.16901

Yi Liu, Wei-Mao Wang, Ying-fei Lu, Lu Feng, Li Li, Ming-zhu Pan, Yu Sun, Chun-wai Suen, Wei Guo, Jian-xin Pang, Jin-Fang Zhang, and Wei-Ming Fu
50655-50664
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Associations between LMO1 gene polymorphisms and Wilms’ tumor susceptibility

https://doi.org/10.18632/oncotarget.16926

Guo-Chang Liu, Zhen-Jian Zhuo, Shi-Bo Zhu, Jinhong Zhu, Wei Jia, Zhang Zhao, Jin-Hua Hu, Jing He, Feng-Hua Wang, and Wen Fu
50665-50672
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Association of genetic polymorphisms in IL1R1 and IL1R2 genes with IgA nephropathy in the Han Chinese population

https://doi.org/10.18632/oncotarget.16929

Maowei Xie, Daofa Zhang, Yin Zhang, Xiaohong Yang, Yan Su, Yanni Wang, Haiyang Huang, Hui Han, Wenning Li, Keying Fu, Huiluan Su, Wentan Xu, and Jiali Wei
50673-50679
Abstract  |  PDF  |  Full Text  |  How to cite

The miR106a~363Xpcl1 miRNA cluster induces murine T cell lymphoma despite transcriptional activation of the p27Kip1 cell cycle inhibitor

https://doi.org/10.18632/oncotarget.16932

Daniel A. Kuppers, Thomas M. Schmitt, Harry C. Hwang, Lavanya Samraj, Bruce E. Clurman, and Matthew L. Fero
50680-50691
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Effects of increased Kindlin2 expression in bladder cancer stromal fibroblasts

https://doi.org/10.18632/oncotarget.17021

Jitao Wu, Cuicui Yu, Li Cai, Youyi Lu, Lei Jiang, Chu Liu, Yongwei Li, Fan Feng, Zhenli Gao, Zhe Zhu, Shengqiang Yu, Hejia Yuan, and Yuanshan Cui
50692-50703
Abstract  |  PDF  |  Full Text  |  How to cite

A prediction model for distinguishing lung squamous cell carcinoma from adenocarcinoma

https://doi.org/10.18632/oncotarget.17038

Hui Li, Zhengran Jiang, Qixin Leng, Fan Bai, Juan Wang, Xiaosong Ding, Yuehong Li, Xianghong Zhang, HongBin Fang, Harris G. Yfantis, Lingxiao Xing, and Feng Jiang
50704-50714
Abstract  |  PDF  |  Full Text  |  How to cite

TGFbeta and miRNA regulation in familial and sporadic breast cancer

https://doi.org/10.18632/oncotarget.14899

Katia Danza, Simona De Summa, Rosamaria Pinto, Brunella Pilato, Orazio Palumbo, Massimo Carella, Ondina Popescu, Maria Digennaro, Rosanna Lacalamita, and Stefania Tommasi
50715-50723
Abstract  |  PDF  |  Full Text  |  How to cite

TRAILR1 as a novel surface marker for circulating giant cell tumor of bone

https://doi.org/10.18632/oncotarget.17042

Jian-Xiang Liu, Zhi-Cai Zhang, Zeng-Wu Shao, Fei-Fei Pu, Bai-Chuan Wang, Yu-Kun Zhang, Xian-Lin Zeng, Xiao-Dong Guo, Shu-Hua Yang, and Tong-Chuan He
50724-50730
Abstract  |  PDF  |  Full Text  |  How to cite

Macrophages promote the progression of premalignant mammary lesions to invasive cancer

https://doi.org/10.18632/oncotarget.14913

Emily C. Carron, Samuel Homra, Jillian Rosenberg, Seth B. Coffelt, Frances Kittrell, Yiqun Zhang, Chad J. Creighton, Suzanne A. Fuqua, Daniel Medina, and Heather L. Machado
50731-50746
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Curcumin induces G2/M cell cycle arrest and apoptosis of head and neck squamous cell carcinoma in vitro and in vivo through ATM/Chk2/p53dependent pathway

https://doi.org/10.18632/oncotarget.17096

An Hu, Jing-Juan Huang, Jing-Fei Zhang, Wei-Jun Dai, Rui-Lin Li, Zhao-Yang Lu, Jun-Li Duan, Ji-Ping Li, Xiao-Ping Chen, Jing-Ping Fan, Wei-Hua Xu, and Hong-Liang Zheng
50747-50760
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification of a RNASeq based prognostic signature with five lncRNAs for lung squamous cell carcinoma

https://doi.org/10.18632/oncotarget.17098

Rui-Xue Tang, Wen-Jie Chen, Rong-Quan He, Jiang-Hui Zeng, Liang Liang, Shi-Kang Li, Jie Ma, Dian-Zhong Luo, and Gang Chen
50761-50773
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Correlation between hormone receptor status and depressive symptoms in patients with metastatic breast cancer

https://doi.org/10.18632/oncotarget.15037

Xiangyu Guo, Junnan Xu, Ying E, Zhifu Yu, and Tao Sun
50774-50781
Abstract  |  PDF  |  Full Text  |  How to cite

PD1 mRNA expression in peripheral blood cells and its modulation characteristics in cancer patients

https://doi.org/10.18632/oncotarget.15006

Wei Wang, Ge Shen, Shikai Wu, Shiping Song, Yanli Ni, Zhuoyao Suo, Xiangying Meng, Dan Li, Lin Zhou, Rimin Hao, Yaowei Zhao, Li Bai, Lili Hou, Bing Liu, and Guangxian Liu
50782-50791
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Impact of country of birth on genetic testing of metastatic lung adenocarcinomas in France: African women exhibit a mutational spectrum more similar to Asians than to Caucasians

https://doi.org/10.18632/oncotarget.15132

Raphael Saffroy, Jean-François Morère, Nelly Bosselut, Pasquale F. Innominato, Jocelyne Hamelin, Jean Trédaniel, Sophie Masse, Véronique Dussaule-Duchatelle, André Balaton, Pierre Validire, Catherine Guettier, Mohamed Bouchahda, and Antoinette Lemoine
50792-50803
Abstract  |  PDF  |  Full Text  |  How to cite

Low PCA3 expression is a marker of poor differentiation in localized prostate tumors: exploratory analysis from 12076 patients

https://doi.org/10.18632/oncotarget.15133

Mohammed Alshalalfa, Gerald W. Verhaegh, Ewan A. Gibb, Maria Santiago-Jiménez, Nicholas Erho, Jennifer Jordan, Kasra Yousefi, Lucia L.C. Lam, Tyler Kolisnik, Jijumon Chelissery, Roland Seiler, Ashley E. Ross, R. Jeffrey Karnes, Edward M. Schaeffer, Tamara T. Lotan, Robert B. Den, Stephen J. Freedland, Elai Davicioni, Eric A. Klein, and Jack A. Schalken
50804-50813
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

GSK1059615 kills head and neck squamous cell carcinoma cells possibly via activating mitochondrial programmed necrosis pathway

https://doi.org/10.18632/oncotarget.15135

Jing Xie, Quan Li, Xi Ding, and Yunyun Gao
50814-50823
Abstract  |  PDF  |  Full Text  |  How to cite

Lack of association between the pancreatitis risk allele CELHYB and pancreatic cancer

https://doi.org/10.18632/oncotarget.15137

Koji Shindo, Jun Yu, Masaya Suenaga, Shahriar Fesharakizadeh, Koji Tamura, Jose Alejandro Navarro Almario, Aaron Brant, Michael Borges, Abdulrehman Siddiqui, Lisa Datta, Christopher L. Wolfgang, Ralph H. Hruban, Alison Patricia Klein, and Michael Goggins
50824-50831
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Antitumor efficacy of theliatinib in esophageal cancer patientderived xenografts models with epidermal growth factor receptor EGFR overexpression and gene amplification

https://doi.org/10.18632/oncotarget.17243

Yongxin Ren, Jianming Zheng, Shiming Fan, Linfang Wang, Min Cheng, Dongxia Shi, Wei Zhang, Renxiang Tang, Ying Yu, Longxian Jiao, Jun Ni, Haibin Yang, Huaqing Cai, Fang Yin, Yunxin Chen, Feng Zhou, Weihan Zhang, Weiguo Qing, and Weiguo Su
50832-50844
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Grape seed extracts modify the outcome of oxaliplatin in colon cancer cells by interfering with cellular mechanisms of drug cytotoxicity

https://doi.org/10.18632/oncotarget.15139

Letizia Porcelli, Rosa Maria Iacobazzi, Anna Elisa Quatrale, Carlo Bergamini, Nunzio Denora, Pasquale Crupi, Donato Antonacci, Anita Mangia, Giovanni Simone, Nicola Silvestris, and Amalia Azzariti
50845-50863
Abstract  |  PDF  |  Full Text  |  How to cite

Association between rs2853669 in TERT gene and the risk and prognosis of human cancer: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.15140

Na Shen, Yanjun Lu, Xiong Wang, Jing Peng, Yaowu Zhu, and Liming Cheng
50864-50872
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Inhibition and deficiency of the immunoproteasome subunit LMP7 suppress the development and progression of colorectal carcinoma in mice

https://doi.org/10.18632/oncotarget.15141

Julia Koerner, Thomas Brunner, and Marcus Groettrup
50873-50888
Abstract  |  PDF  |  Full Text  |  How to cite

The Bbox module of CYLD is responsible for its intermolecular interaction and cytoplasmic localization

https://doi.org/10.18632/oncotarget.15142

Songbo Xie, Miao Chen, Siqi Gao, Tao Zhong, Peng Zhou, Dengwen Li, Jun Zhou, Jinmin Gao, and Min Liu
50889-50895
Abstract  |  PDF  |  Full Text  |  How to cite

LGR5 promotes hepatocellular carcinoma metastasis through inducting epithelialmesenchymal transition

https://doi.org/10.18632/oncotarget.15143

Jie Liu, Guo-Zheng Yu, Xiao-Ke Cheng, Xiao-Dong Li, Xian-Tao Zeng, and Xue-Qun Ren
50896-50903
Abstract  |  PDF  |  Full Text  |  How to cite

Autophagy deactivation is associated with severe prostatic inflammation in patients with lower urinary tract symptoms and benign prostatic hyperplasia

https://doi.org/10.18632/oncotarget.15144

Cosimo De Nunzio, Simona Giglio, Antonella Stoppacciaro, Mauro Gacci, Roberto Cirombella, Emidio Luciani, Andrea Tubaro, and Andrea Vecchione
50904-50910
Abstract  |  PDF  |  Full Text  |  How to cite

Perfluorodecanoic acid PFDA promotes gastric cell proliferation via sPLA2IIA

https://doi.org/10.18632/oncotarget.17284

Tianyi Dong, Yanping Peng, Ning Zhong, Fengyan Liu, Hanyu Zhang, Mengchen Xu, Rutao Liu, Mingyong Han, Xingsong Tian, Jihui Jia, Lap Kam Chang, Liang-Hong Guo, and Shili Liu
50911-50920
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Repetitive transcranial magnetic stimulation for treatment of lactacystininduced Parkinsonian rat model

https://doi.org/10.18632/oncotarget.17285

Maowen Ba, Guozhao Ma, Chao Ren, Xuwen Sun, and Min Kong
50921-50929
Abstract  |  PDF  |  Full Text  |  How to cite

Germline whole exome sequencing and largescale replication identifies FANCM as a likely high grade serous ovarian cancer susceptibility gene

https://doi.org/10.18632/oncotarget.15871

Ed Dicks, Honglin Song, Susan J. Ramus, Elke Van Oudenhove, Jonathan P. Tyrer, Maria P. Intermaggio, Siddhartha Kar, Patricia Harrington, David D. Bowtell, AOCS Study Group, Mine S. Cicek, Julie M. Cunningham, Brooke L. Fridley, Jennifer Alsop, Mercedes Jimenez-Linan, Anna Piskorz, Teodora Goranova, Emma Kent, Nadeem Siddiqui, James Paul, Robin Crawford, Samantha Poblete, Shashi Lele, Lara Sucheston-Campbell, Kirsten B. Moysich, Weiva Sieh, Valerie McGuire, Jenny Lester, Kunle Odunsi, Alice S. Whittemore, Natalia Bogdanova, Matthias Dürst, Peter Hillemanns, Beth Y. Karlan, Aleksandra Gentry-Maharaj, Usha Menon, Marc Tischkowitz, Douglas Levine, James D. Brenton, Thilo Dörk, Ellen L. Goode, Simon A. Gayther, and Paul D.P. Pharoah
50930-50940
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The prognostic role of pretreatment epidermal growth factor receptor T790M mutation in advanced nonsmall cell lung cancer patients treated with EGFR tyrosine kinase inhibitors

https://doi.org/10.18632/oncotarget.16222

Guangzhi Ma, Jing Zhang, Liyuan Yin, Hai Jiang, Weiwei Zhang, Yanlin Song, and Ming Liu
50941-50948
Abstract  |  PDF  |  Full Text  |  How to cite

mRNA in exosomas as a liquid biopsy in nonHodgkin Lymphoma: a multicentric study by the Spanish Lymphoma Oncology Group

https://doi.org/10.18632/oncotarget.16435

Mariano Provencio, Marta Rodríguez, Blanca Cantos, Pilar Sabín, Cristina Quero, Francisco R. García-Arroyo, Antonio Rueda, Constanza Maximiano, Delvys Rodríguez-Abreu, Antonio Sánchez, Javier Silva, Vanesa García, and on behalf of GOTEL (Spanish Lymphoma Oncology Group)
50949-50957
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

EETs reduces LPSinduced hyperpermeability by targeting GRP78 mediated Src activation and subsequent Rho/ROCK signaling pathway

https://doi.org/10.18632/oncotarget.17331

Ruolan Dong, Danli Hu, Yan Yang, Zhihui Chen, Menglu Fu, Dao Wen Wang, Xizhen Xu, and Ling Tu
50958-50971
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Connexin40 controls endothelial activation by dampening NFκB activation

https://doi.org/10.18632/oncotarget.16438

Jean-Francois Denis, K.E. Ludwig Scheckenbach, Anna Pfenniger, Merlijn J. Meens, Rob Krams, Lucile Miquerol, Steven Taffet, Marc Chanson, Mario Delmar, and Brenda R. Kwak
50972-50986
Abstract  |  PDF  |  Full Text  |  How to cite

Is FTO gene variant related to cancer risk independently of adiposity An updated metaanalysis of 129467 cases and 290633 controls

https://doi.org/10.18632/oncotarget.16446

Yu Kang, Fang Liu, and Yao Liu
50987-50996
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Peptidebased PET imaging of the tumor restricted IL13RA2 biomarker

https://doi.org/10.18632/oncotarget.16549

Kiran Kumar Solingapuram Sai, Anirudh Sattiraju, Frankis G. Almaguel, Ang Xuan, Stephanie Rideout, Rahul S. Krishnaswamy, JoAnn Zhang, Denise M. Herpai, Waldemar Debinski, and Akiva Mintz
50997-51007
Abstract  |  PDF  |  Full Text  |  How to cite

Ascites promotes cell migration through the repression of miR125b in ovarian cancer

https://doi.org/10.18632/oncotarget.16846

Lan Yang, Xiaoli Zhang, Yiming Ma, Xinhua Zhao, Bin Li, and Hongying Wang
51008-51015
Abstract  |  PDF  |  Full Text  |  How to cite

The influence of marital status on the survival of patients with Hodgkin lymphoma

https://doi.org/10.18632/oncotarget.16879

Fangfang Wang, Xiaoyan Xie, Xiaoming Yang, Guoqing Jiang, and Jian Gu
51016-51023
Abstract  |  PDF  |  Full Text  |  How to cite

Relevance of CCL3/CCR5 axis in oral carcinogenesis

https://doi.org/10.18632/oncotarget.16882

Janine Mayra da Silva, Tálita Pollyanna Moreira dos Santos, Lays Martin Sobral, Celso Martins Queiroz-Junior, Milene Alvarenga Rachid, Amanda E.I. Proudfoot, Gustavo Pompermaier Garlet, Aline Carvalho Batista, Mauro Martins Teixeira, Andréia Machado Leopoldino, Remo Castro Russo, and Tarcília Aparecida Silva
51024-51036
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Structural basis of a novel heterodimeric Fc for bispecific antibody production

https://doi.org/10.18632/oncotarget.17558

Hudie Wei, Haiyan Cai, Yuhao Jin, Pilin Wang, Qingqing Zhang, Yihui Lin, Weixiao Wang, Jinke Cheng, Naiyan Zeng, Ting Xu, and Aiwu Zhou
51037-51049
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Establishment of a mouse xenograft model of metastatic adrenocortical carcinoma

https://doi.org/10.18632/oncotarget.16909

Aurélie Morin, Carmen Ruggiero, Estelle Robidel, Mabrouka Doghman-Bouguerra, Atze T. Das, Rémy Castellano, Emmanuelle Josselin, Judith Favier, and Enzo Lalli
51050-51057
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Upregulation of long noncoding RNA SPRY4IT1 promotes tumor cell migration and invasion in lung adenocarcinoma

https://doi.org/10.18632/oncotarget.16918

Xia Zhang, Qingyan Chi, and Zhenhua Zhao
51058-51065
Abstract  |  PDF  |  Full Text  |  How to cite

Protective effect of madecassoside on H2O2induced oxidative stress and autophagy activation in human melanocytes

https://doi.org/10.18632/oncotarget.17654

Yuting Ling, Qingli Gong, Xixi Xiong, Li Sun, Wene Zhao, Wenyuan Zhu, and Yan Lu
51066-51075
Abstract  |  PDF  |  Full Text  |  How to cite

Comparison of longterm outcome between hemicolectomy and partial colectomy in the elderly: a large populationbased study

https://doi.org/10.18632/oncotarget.16993

Xu Guan, Hanqing Hu, Wei Chen, Zheng Jiang, Zheng Liu, Zhixun Zhao, Yinggang Chen, Guiyu Wang, and Xishan Wang
51076-51085
Abstract  |  PDF  |  Full Text  |  How to cite

Preliminary biological evaluation of 18FAlFNOTAMALCysAnnexin V as a novel apoptosis imaging agent

https://doi.org/10.18632/oncotarget.16994

Chunxiong Lu, Quanfu Jiang, Minjin Hu, Cheng Tan, Huixin Yu, and Zichun Hua
51086-51095
Abstract  |  PDF  |  Full Text  |  How to cite

Peroxiredoxin 6 overexpression attenuates lipopolysaccharideinduced acute kidney injury

https://doi.org/10.18632/oncotarget.17002

Dong Hun Lee, Ju Ho Park, Sang Bae Han, Do Young Yoon, Yu Yeon Jung, and Jin Tae Hong
51096-51107
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Heterogeneous nuclear ribonucleoprotein hnRNP L promotes DNA damageinduced cell apoptosis by enhancing the translation of p53

https://doi.org/10.18632/oncotarget.17003

Ji-Young Seo, Do-Yeon Kim, Seong-Hoon Kim, Hyo-Jin Kim, Hye Guk Ryu, Juhyun Lee, Kyung-Ha Lee, and Kyong-Tai Kim
51108-51122
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

HTLV1 Tax upregulates early growth response protein 1 through nuclear factorκB signaling

https://doi.org/10.18632/oncotarget.17699

Qingsong Huang, Zhiguo Niu, Jingxian Han, Xihong Liu, Zhuangwei Lv, Huanhuan Li, Lixiang Yuan, Xiangping Li, Shuming Sun, Hui Wang, and Xinxiang Huang
51123-51133
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The landscape of DNA methylationmediated regulation of long noncoding RNAs in breast cancer

https://doi.org/10.18632/oncotarget.17705

Chunlong Zhang, Xinyu Wang, Xuecang Li, Ning Zhao, Yihan Wang, Xiaole Han, Ce Ci, Jian Zhang, Meng Li, and Yan Zhang
51134-51150
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

CD147 functions as the signaling receptor for extracellular divalent copper in hepatocellular carcinoma cells

https://doi.org/10.18632/oncotarget.17712

Pengfei Ding, Xin Zhang, Shujuan Jin, Bo Duan, Pengxiang Chu, Yufei Zhang, Zhi-Nan Chen, Bin Xia, and Fei Song
51151-51163
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The oxidometabolic driver ATF4 enhances temozolamide chemoresistance in human gliomas

https://doi.org/10.18632/oncotarget.17737

Daishi Chen, Manfred Rauh, Michael Buchfelder, Ilker Y. Eyupoglu, and Nicolai Savaskan
51164-51176
Abstract  |  PDF  |  Full Text  |  How to cite

Netrin1 promotes gastric cancer cell proliferation and invasion via the receptor neogenin through PI3K/AKT signaling pathway

https://doi.org/10.18632/oncotarget.17750

Kai Yin, Linjun Wang, Xuan Zhang, Zhongyuan He, Yiwen Xia, Jianghao Xu, Song Wei, Bowen Li, Zheng Li, Guangli Sun, Qing Li, Hao Xu, and Zekuan Xu
51177-51189
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MicroRNA200c as a prognostic and sensitivity marker for platinum chemotherapy in advanced gastric cancer

https://doi.org/10.18632/oncotarget.17087

Min Li, Kangsheng Gu, Wei Liu, Xiaoque Xie, Xiaolu Huang, and Yiyin Zhang
51190-51199
Abstract  |  PDF  |  Full Text  |  How to cite

Colorectal cancer at high risk of peritoneal metastases: long term outcomes of a pilot study on adjuvant laparoscopic HIPEC and future perspectives

https://doi.org/10.18632/oncotarget.17158

Charlotte E.L. Klaver, Roos Stam, Didi A.M. Sloothaak, Johannes Crezee, Willem A. Bemelman, Cornelis J.A. Punt, and Pieter J. Tanis
51200-51209
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PD1 and PDL1 expression in 132 recurrent nasopharyngeal carcinoma: the correlation with anemia and outcomes

https://doi.org/10.18632/oncotarget.17214

Yajuan Zhou, Jingjing Miao, Haijun Wu, Hao Tang, Jing Kuang, Xiaoyi Zhou, Yi Peng, Desheng Hu, Dingbo Shi, Wuguo Deng, Xinyue Cao, Chong Zhao, and Conghua Xie
51210-51223
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Critical analysis of the major and ancillary imaging features of LIRADS on 127 proven HCCs evaluated with functional and morphological MRI: Lights and shadows

https://doi.org/10.18632/oncotarget.17227

Vincenza Granata, Roberta Fusco, Antonio Avallone, Francesco Filice, Fabiana Tatangelo, Mauro Piccirillo, Roberto Grassi, Francesco Izzo, and Antonella Petrillo
51224-51237
Abstract  |  PDF  |  Full Text  |  How to cite

Engineering a highaffinity humanized antiCD24 antibody to target hepatocellular carcinoma by a novel CDR grafting design

https://doi.org/10.18632/oncotarget.17228

Fumou Sun, Tong Wang, Jiahao Jiang, Yang Wang, Zhaoxiong Ma, Zhaoting Li, Yue Han, Mingzhu Pan, Jialing Cai, Min Wang, and Juan Zhang
51238-51252
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Spatial function of the oxidative DNA damage response in radiation induced bystander effects in intra and intersystem of Caenorhabditis elegans

https://doi.org/10.18632/oncotarget.17229

Qingqing Li, Jue Shi, Lianyun Chen, Furu Zhan, Hang Yuan, Jun Wang, An Xu, and Lijun Wu
51253-51263
Abstract  |  PDF  |  Full Text  |  How to cite

Modeling African American prostate adenocarcinoma by inducing defined genetic alterations in organoids

https://doi.org/10.18632/oncotarget.17230

Kenji Unno, Meejeon Roh, Young A. Yoo, Yousef Al-Shraideh, Lu Wang, Larisa Nonn, and Sarki A. Abdulkadir
51264-51276
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Ocular Behcet’s disease is associated with aberrant methylation of interferon regulatory factor 8 IRF8 in monocytederived dendritic cells

https://doi.org/10.18632/oncotarget.17235

Yiguo Qiu, Yunyun Zhu, Hongsong Yu, Shenglan Yi, Wencheng Su, Qingfeng Cao, Gangxiang Yuan, Aize Kijlstra, and Peizeng Yang
51277-51287
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Correlation between microRNA143 in peripheral blood mononuclear cells and disease severity in patients with psoriasis vulgaris

https://doi.org/10.18632/oncotarget.17260

Yi-Zhi Zheng, Chun-Feng Chen, Li-Ying Jia, Tu-Gen Yu, Jie Sun, and Xiao-Yong Wang
51288-51295
Abstract  |  PDF  |  Full Text  |  How to cite

Identification of deubiquitinase targets of isothiocyanates using SILACassisted quantitative mass spectrometry

https://doi.org/10.18632/oncotarget.17261

Ann P. Lawson, Daniel W. Bak, D. Alexander Shannon, Marcus J.C. Long, Tushara Vijaykumar, Runhan Yu, Farid El Oualid, Eranthie Weerapana, and Lizbeth Hedstrom
51296-51316
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

APEX2enhanced electron microscopy distinguishes sigma1 receptor localization in the nucleoplasmic reticulum

https://doi.org/10.18632/oncotarget.17906

Timur A. Mavlyutov, Huan Yang, Miles L. Epstein, Arnold E. Ruoho, Jay Yang, and Lian-Wang Guo
51317-51330
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Expression and clinical significance of CD147 in renal cell carcinoma: a metaanalysis

https://doi.org/10.18632/oncotarget.17376

Hui Li, Dongwen Wu, Shupeng Shi, Yadong Xu, Ling Wei, Jing Liu, and Yanting Liu
51331-51344
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Predictors of acute kidney injury after paraquat intoxication

https://doi.org/10.18632/oncotarget.17975

Cheng-Hao Weng, Hui-Hsiang Chen, Ching-Chih Hu, Wen-Hung Huang, Ching-Wei Hsu, Jen-Fen Fu, Wey-Ran Lin, I-Kwan Wang, and Tzung-Hai Yen
51345-51354
Abstract  |  PDF  |  Full Text  |  How to cite

Identification of novel small molecule Beclin 1 mimetics activating autophagy

https://doi.org/10.18632/oncotarget.17977

Jia Yu, Lan Lan, Seth J. Lewin, Steven A. Rogers, Anuradha Roy, Xiaoqing Wu, Philip Gao, John Karanicolas, Jeffrey Aubé, Baiwang Sun, and Liang Xu
51355-51369
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Fusion between M2macrophages and cancer cells results in a subpopulation of radioresistant cells with enhanced DNArepair capacity

https://doi.org/10.18632/oncotarget.17986

Annelie Lindström, Kristine Midtbö, Lars-Gunnar Arnesson, Stina Garvin, and Ivan Shabo
51370-51386
Abstract  |  PDF  |  Full Text  |  How to cite

DNA hypomethylation of CBS promoter induced by folate deficiency is a potential noninvasive circulating biomarker for colorectal adenocarcinomas

https://doi.org/10.18632/oncotarget.17988

Geng Xue, Chao-Jing Lu, Shu-Jun Pan, Yin-Ling Zhang, Hui Miao, Shi Shan, Xiao-Ting Zhu, and Yi Zhang
51387-51401
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

BRD4 facilitates DNA damage response and represses CBX5/Heterochromatin protein 1 HP1

https://doi.org/10.18632/oncotarget.17572

Georgios Pongas, Marianne K. Kim, Dong J. Min, Carrie D. House, Elizabeth Jordan, Natasha Caplen, Sirisha Chakka, Joyce Ohiri, Michael J. Kruhlak, and Christina M. Annunziata
51402-51415
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tumor biomarker conversion between primary and metastatic breast cancer: mRNA assessment and its concordance with immunohistochemistry

https://doi.org/10.18632/oncotarget.18006

Stefan Stefanovic, Ralph Wirtz, Thomas M. Deutsch, Andreas Hartkopf, Peter Sinn, Zsuzsanna Varga, Bettina Sobottka, Lakis Sotiris, Florin-Andrei Taran, Christoph Domschke, Andre Hennigs, Sara Y. Brucker, Christof Sohn, Florian Schuetz, Andreas Schneeweiss, and Markus Wallwiener
51416-51428
Abstract  |  PDF  |  Full Text  |  How to cite

DecitabineVorinostat combination treatment in acute myeloid leukemia activates pathways with potential for novel triple therapy

https://doi.org/10.18632/oncotarget.18009

Christine S. Young, Kathryn M. Clarke, Laura M. Kettyle, Alexander Thompson, and Ken I. Mills
51429-51446
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

SIRT1 inhibition promotes atherosclerosis through impaired autophagy

https://doi.org/10.18632/oncotarget.17691

Xiaofeng Yang, Jingyuan Wei, Yanhao He, Ting Jing, Yanxiang Li, Yunfang Xiao, Bo Wang, Weirong Wang, Jiye Zhang, and Rong Lin
51447-51461
Abstract  |  PDF  |  Full Text  |  How to cite

Activation of PERK branch of ER stress mediates homocysteineinduced BKCa channel dysfunction in coronary artery via FoxO3adependent regulation of atrogin1

https://doi.org/10.18632/oncotarget.17721

Wen-Tao Sun, Xiang-Chong Wang, Shiu-Kwong Mak, Guo-Wei He, Xiao-Cheng Liu, Malcolm John Underwood, and Qin Yang
51462-51477
Abstract  |  PDF  |  Full Text  |  How to cite

Combination of Fe/Cu –chelators and docosahexaenoic acid: an exploration for the treatment of colorectal cancer

https://doi.org/10.18632/oncotarget.17807

Nanhui Yu, Hong Zhu, Yuan Yang, Yiming Tao, Fengbo Tan, Qian Pei, Yuan Zhou, Xiangping Song, Qiurong Tan, and Haiping Pei
51478-51491
Abstract  |  PDF  |  Full Text  |  How to cite

Bevacizumab significantly increases the risks of hypertension and proteinuria in cancer patients: A systematic review and comprehensive metaanalysis

https://doi.org/10.18632/oncotarget.18190

Tingting Zhao, Xiaonan Wang, Tingting Xu, Xiaodong Xu, and Zhihong Liu
51492-51506
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Bisphenol A exposure promotes HTR8/SVneo cell migration and impairs mouse placentation involving upregulation of integrinβ1 and MMP9 and stimulation of MAPK and PI3K signaling pathways

https://doi.org/10.18632/oncotarget.17882

Xi Lan, Li-Juan Fu, Jun Zhang, Xue-Qing Liu, Hui-Jie Zhang, Xue Zhang, Ming-Fu Ma, Xue-Mei Chen, Jun-Lin He, Lian-Bing Li, Ying-Xiong Wang, and Yu-Bin Ding
51507-51521
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prognostic microRNAs in upper tract urothelial carcinoma: multicenter and international validation study

https://doi.org/10.18632/oncotarget.17884

Laura Izquierdo, Ruth Montalbo, Mercedes Ingelmo-Torres, Carme Mallofré, Miguel Ramírez-Backhaus, Jose Rubio, Antoine Van der Heijden, Ewout Schaafsma, Antonio Lopez-Beltran, Ana Blanca, Nathan Lawrentschuk, Antonio Alcaraz, and Lourdes Mengual
51522-51529
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

HPVassociated differential regulation of tumor metabolism in oropharyngeal head and neck cancer

https://doi.org/10.18632/oncotarget.17887

Young-Suk Jung, Abdo J. Najy, Wei Huang, Seema Sethi, Michael Snyder, Wael Sakr, Gregory Dyson, Maik Hüttemann, Icksoo Lee, Rouba Ali-Fehmi, Silvia Franceschi, Linda Struijk, Harold E. Kim, Ikuko Kato, and Hyeong-Reh Choi Kim
51530-51541
Abstract  |  PDF  |  Full Text  |  How to cite

More precise prediction in Chinese patients with penile squamous cell carcinoma: protein kinase CK2α catalytic subunit CK2α as a poor prognosticator

https://doi.org/10.18632/oncotarget.17935

Zai-Shang Li, Chuang-Zhong Deng, Yun-Lin Ye, Kai Yao, Sheng-Jie Guo, Jie-Ping Chen, Yong-Hong Li, Zi-Ke Qin, Zhuo-Wei Liu, Bin Wang, Qi Zhao, Peng Chen, Qi-Wu Mi, Xiao-Feng Chen, Hui Han, and and Fang-Jian Zhou
51542-51550
Abstract  |  PDF  |  Full Text  |  How to cite

A high plasma Ddimer level predicts poor prognosis in gynecological tumors in East Asia area: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.17936

Lei Xu, Fan He, Hongcai Wang, Bei Gao, Huini Wu, and Shuping Zhao
51551-51558
Abstract  |  PDF  |  Full Text  |  How to cite

The metastasis suppressor CD82/KAI1 regulates cell migration and invasion via inhibiting TGFβ 1/Smad signaling in renal cell carcinoma

https://doi.org/10.18632/oncotarget.18086

Jundong Zhu, Chao Liang, Yibo Hua, Chenkui Miao, Jianzhong Zhang, Aiming Xu, Kai Zhao, Shouyong Liu, Ye Tian, Huiyu Dong, Chao Zhang, Pu Li, Shifeng Su, Chao Qin, and Zengjun Wang
51559-51568
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genetic evaluations of Chinese patients with odontohypophosphatasia resulting from heterozygosity for mutations in the tissuenonspecific alkaline phosphatase gene

https://doi.org/10.18632/oncotarget.18093

Jia Wan, Li Zhang, Tang Liu, and Yewei Wang
51569-51577
Abstract  |  PDF  |  Full Text  |  How to cite

GCSF inhibits LFA1mediated CD4+ T cell functions by inhibiting Lck and ZAP70

https://doi.org/10.18632/oncotarget.18194

Shasha Zhao, Zhenyang Gu, Li Wang, Lixun Guan, Feiyan Wang, Nan Yang, Lan Luo, Zhe Gao, Yingwei Song, Lili Wang, Daihong Liu, and Chunji Gao
51578-51590
Abstract  |  PDF  |  Full Text  |  How to cite

Malignant pericytes expressing GT198 give rise to tumor cells through angiogenesis

https://doi.org/10.18632/oncotarget.18196

Liyong Zhang, Yan Wang, Mohammad H. Rashid, Min Liu, Kartik Angara, Nahid F. Mivechi, Nita J. Maihle, Ali S. Arbab, and Lan Ko
51591-51607
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MB42/MB43 transcripts of IGHMMSET fusion gene in t4;14pos multiple myeloma indicate poor prognosis

https://doi.org/10.18632/oncotarget.18209

Feng Li, Yong-Ping Zhai, Ting Lai, Qian Zhao, Hui Zhang, Yu-Mei Tang, and Jian Hou
51608-51620
Abstract  |  PDF  |  Full Text  |  How to cite

Bromodomain inhibition shows antitumoral activity in mice and human luminal breast cancer

https://doi.org/10.18632/oncotarget.18255

Montserrat Pérez-Salvia, Laia Simó-Riudalbas, Pere Llinàs-Arias, Laura Roa, Fernando Setien, Marta Soler, Manuel Castro de Moura, James E. Bradner, Eva Gonzalez-Suarez, Catia Moutinho, and Manel Esteller
51621-51629
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prognostic significance of PDL1 expression and 18FFDG PET/CT in surgical pulmonary squamous cell carcinoma

https://doi.org/10.18632/oncotarget.18257

Minghui Zhang, Dalong Wang, Qi Sun, Haihong Pu, Yan Wang, Shu Zhao, Yan Wang, and Qiangyuan Zhang
51630-51640
Abstract  |  PDF  |  Full Text  |  How to cite

PDL1 and intratumoral immune response in breast cancer

https://doi.org/10.18632/oncotarget.18305

Zhi-Qiang Wang, Katy Milne, Heather Derocher, John R. Webb, Brad H. Nelson, and Peter H. Watson
51641-51651
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Experimental study on the therapeutic effect and underlining mechanisms of positron in pancreatic cancer cells

https://doi.org/10.18632/oncotarget.18366

Ying Wang, Ming Li, Rao Diao, Brian Tung, Dalong Zhang, and Yaming Li
51652-51662
Abstract  |  PDF  |  Full Text  |  How to cite

Impact of insurance status on the survival of gallbladder cancer patients

https://doi.org/10.18632/oncotarget.18381

Zhiqiang Chen, Wen Gao, Liyong Pu, Long Zhang, Guoyong Han, Qin Zhu, Xiangcheng Li, Jindao Wu, and Xuehao Wang
51663-51674
Abstract  |  PDF  |  Full Text  |  How to cite

Autophagy is required for crizotinibinduced apoptosis in METamplified gastric cancer cells

https://doi.org/10.18632/oncotarget.18386

Rebecca D. Schroeder, Woonyoung Choi, David S. Hong, and David J. McConkey
51675-51687
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miR487b mitigates chronic heart failure through inhibition of the IL33/ST2 signaling pathway

https://doi.org/10.18632/oncotarget.18393

En-Wei Wang, Xu-Sheng Jia, Chang-Wu Ruan, and Zhi-Ru Ge
51688-51702
Abstract  |  PDF  |  Full Text  |  How to cite

Identification of dysregulated long noncoding RNAs/microRNAs/mRNAs in TNM I stage lung adenocarcinoma

https://doi.org/10.18632/oncotarget.18512

Ziqiang Tian, Shiwang Wen, Yuefeng Zhang, Xinqiang Shi, Yonggang Zhu, Yanzhao Xu, Huilai Lv, and Guiying Wang
51703-51718
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Insulinlike growth factor1 is a negative modulator of glucagon secretion

https://doi.org/10.18632/oncotarget.18514

Elettra Mancuso, Gaia C. Mannino, Concetta Di Fatta, Anastasia Fuoco, Rosangela Spiga, Francesco Andreozzi, and Giorgio Sesti
51719-51732
Abstract  |  PDF  |  Full Text  |  How to cite

Inhibition of FAK kinase activity preferentially targets cancer stem cells

https://doi.org/10.18632/oncotarget.18517

Vihren N. Kolev, Winnie F. Tam, Quentin G. Wright, Sean P. McDermott, Christian M. Vidal, Irina M. Shapiro, Qunli Xu, Max S. Wicha, Jonathan A. Pachter, and David T. Weaver
51733-51747
Abstract  |  PDF  |  Full Text  |  How to cite

Inhibition of COX2 enhances the chemosensitivity of dichloroacetate in cervical cancer cells

https://doi.org/10.18632/oncotarget.18518

Bo Li, Xinzhe Li, Haojun Xiong, Peng Zhou, Zhenhong Ni, Teng Yang, Yan Zhang, Yijun Zeng, Jintao He, Fan Yang, Nan Zhang, Yuting Wang, Yingru Zheng, and Fengtian He
51748-51757
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Meta-Analysis

Efficacy and safety of longterm therapy for highgrade glioma with temozolomide: A metaanalysis

https://doi.org/10.18632/oncotarget.17401

Weilin Xu, Tao Li, Liansheng Gao, Jingwei Zheng, Anwen Shao, and Jianmin Zhang
51758-51765
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Association between PSCA gene polymorphisms and the risk of cancer: an updated metaanalysis and trial sequential analysis

https://doi.org/10.18632/oncotarget.17011

Zhiqiang Qin, Jingyuan Tang, Xiao Li, Yajie Yu, Chuanjie Zhang, Peng Han, Ran Li, Xuping Jiang, Chengdi Yang, Wei Wang, Min Tang, and Wei Zhang
51766-51778
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Survival benefit of immune checkpoint inhibitors according to the histology in nonsmallcell lung cancer: A metaanalysis and review

https://doi.org/10.18632/oncotarget.17213

Bum Jun Kim, Jung Han Kim, and Hyeong Su Kim
51779-51785
Abstract  |  PDF  |  Full Text  |  How to cite

Clinical Research Papers

OGTT 1h serum Cpeptide to plasma glucose concentration ratio is more related to beta cell function and diabetes mellitus

https://doi.org/10.18632/oncotarget.15239

Hongmei Zhang, Bingxian Bian, Fan Hu, and Qing Su
51786-51791
Abstract  |  PDF  |  Full Text  |  How to cite

The clinical utility and outcomes of microwave ablation for colorectal cancer liver metastases

https://doi.org/10.18632/oncotarget.15244

Pengyuan Song, Lijun Sheng, Yahong Sun, Yuji An, Ya Guo, and Yafei Zhang
51792-51799
Abstract  |  PDF  |  Full Text  |  How to cite

Cause of death in patients diagnosed with esophageal cancer in Sweden: a populationbased study

https://doi.org/10.18632/oncotarget.15270

Shao-Hua Xie, Karl Wahlin, and Jesper Lagergren
51800-51809
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Perioperative entecavir for patients with HBVrelated hepatocellular carcinoma and low levels of viral DNA: analysis using propensity score matching

https://doi.org/10.18632/oncotarget.15395

Bao-Hong Yuan, Ru-Hong Li, Wei-Ping Yuan, Bang-De Xiang, Ming-Hua Zheng, Tian Yang, Jian-Hong Zhong, and Le-Qun Li
51810-51816
Abstract  |  PDF  |  Full Text  |  How to cite

Critical role of matrix metallopeptidase 9 in postoperative cognitive dysfunction and agedependent cognitive decline

https://doi.org/10.18632/oncotarget.15545

Jiangjiang Bi, Weiran Shan, Ailin Luo, and Zhiyi Zuo
51817-51829
Abstract  |  PDF  |  Full Text  |  How to cite

Cabazitaxel in recurrent/metastatic squamous cell carcinoma of the head and neck: phase II UNICANCER trial ORL03

https://doi.org/10.18632/oncotarget.15901

Jerome Fayette, Joel Guigay, Christophe Le Tourneau, Marian Degardin, Frederic Peyrade, Eve-Marie Neidhardt, Marie-Paule Sablin, Caroline Even, Florence Orlandini, Béata Juzyna, and Carine Bellera
51830-51839
Abstract  |  PDF  |  Full Text  |  How to cite

Predictive factors of paraaortic lymph nodes metastasis in cervical cancer patients: a retrospective analysis based on 723 paraaortic lymphadenectomy cases

https://doi.org/10.18632/oncotarget.16025

Xiaotian Han, Hao Wen, Xingzhu Ju, Xiaojun Chen, Guihao Ke, Yuqi Zhou, Jin Li, Lingfang Xia, Jia Tang, Shanhui Liang, and Xiaohua Wu
51840-51847
Abstract  |  PDF  |  Full Text  |  How to cite

Individual isotoxic radiation dose escalation based on V20 and advanced technologies benefits unresectable stage III nonsmall cell lung cancer patients treated with concurrent chemoradiotherapy: long term followup

https://doi.org/10.18632/oncotarget.16288

Ming Liu, Zhongtang Wang, Tao Zhou, Antang Zhou, Qian Zhao, Hongsheng Li, Hongfu Sun, Wei Huang, and BaoSheng Li
51848-51858
Abstract  |  PDF  |  Full Text  |  How to cite

Correlation of HAMP gene polymorphisms and expression with the susceptibility and length of hospital stays in Taiwanese children with Kawasaki disease

https://doi.org/10.18632/oncotarget.17700

Ying-Hsien Huang, Kuender D. Yang, Yu-Wen Hsu, Hsing-Fang Lu, Henry Sung-Ching Wong, Hong-Ren Yu, Hsing-Chun Kuo, Fu-Chen Huang, Mao-Hung Lo, Kai-Sheng Hsieh, Su-Fen Chen, Wei-Chiao Chang, and Ho-Chang Kuo
51859-51868
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The effect of intraperitoneal chemotherapy on early pain hyperalgesia in patients following elective laparoscopic transabdominal resection of rectal cancer

https://doi.org/10.18632/oncotarget.18417

Min Liang, Chang-Ying Li, Chun-Guang Ren, Zong-Wang Zhang, and Zhi-Jian Fu
51869-51877
Abstract  |  PDF  |  Full Text  |  How to cite

Reviews

Feasibility of laparoscopic gastrectomy for elderly gastric cancer patients: metaanalysis of nonrandomized controlled studies

https://doi.org/10.18632/oncotarget.16691

Liang Zong, Aiwen Wu, Wenyue Wang, Jingyu Deng, Susumu Aikou, Hiroharu Yamashita, Masahiro Maeda, Masanobu Abe, Duonan Yu, Zhiwei Jiang, Yasuyuki Seto, and Jiafu Ji
51878-51887
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Reduction–oxidation pathways involved in cancer development: a systematic review of literature reviews

https://doi.org/10.18632/oncotarget.17128

Xīn Gào, and Ben Schöttker
51888-51906
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Thymoquinone as an anticancer molecule: from basic research to clinical investigation

https://doi.org/10.18632/oncotarget.17206

Md. Asaduzzaman Khan, Mousumi Tania, Shangyi Fu, and Junjiang Fu
51907-51919
Abstract  |  PDF  |  Full Text  |  How to cite

SETBP1 dysregulation in congenital disorders and myeloid neoplasms

https://doi.org/10.18632/oncotarget.17231

Nicoletta Coccaro, Giuseppina Tota, Antonella Zagaria, Luisa Anelli, Giorgina Specchia, and Francesco Albano
51920-51935
Abstract  |  PDF  |  Full Text  |  How to cite

PD1 signal transduction pathways in T cells

https://doi.org/10.18632/oncotarget.17232

Hugo Arasanz, Maria Gato-Cañas, Miren Zuazo, Maria Ibañez-Vea, Karine Breckpot, Grazyna Kochan, and David Escors
51936-51945
Abstract  |  PDF  |  Full Text  |  How to cite

The epigenetic integrator UHRF1: on the road to become a universal biomarker for cancer

https://doi.org/10.18632/oncotarget.17393

Waseem Ashraf, Abdulkhaleg Ibrahim, Mahmoud Alhosin, Liliyana Zaayter, Khalid Ouararhni, Christophe Papin, Tanveer Ahmad, Ali Hamiche, Yves Mély, Christian Bronner, and Marc Mousli
51946-51962
Abstract  |  PDF  |  Full Text  |  How to cite

Current status of lymph node micrometastasis in gastric cancer

https://doi.org/10.18632/oncotarget.17495

Yang Zhou, Guo-Jing Zhang, Ji Wang, Kai-Yuan Zheng, and Weihua Fu
51963-51969
Abstract  |  PDF  |  Full Text  |  How to cite

Chaperonemediated autophagy substrate proteins in cancer

https://doi.org/10.18632/oncotarget.17583

Ying Tang, Xiong-Wen Wang, Zhan-Hua Liu, Yun-Ming Sun, Yu-Xin Tang, and Dai-Han Zhou
51970-51985
Abstract  |  PDF  |  Full Text  |  How to cite

A summary of relationships between alternative splicing and breast cancer

https://doi.org/10.18632/oncotarget.17727

Zhang Xiping, Wei Qingshan, Zhao Shuai, Yang Hongjian, and Ding Xiaowen
51986-51993
Abstract  |  PDF  |  Full Text  |  How to cite

Associations between two common single nucleotide polymorphisms rs2241766 and rs1501299 of ADIPOQ gene and coronary artery disease in type 2 diabetic patients: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.18317

Na Zhao, Ningxia Li, Shengjun Zhang, Qiang Ma, Cong Ma, Xiaolan Yang, Jie Yin, Rui Zhang, Jing Li, Xiaogang Yang, and Tao Cui
51994-52005
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Case Reports

Intratumoral coagulation by radiofrequency ablation facilitated the laparoscopic resection of giant hepatic hemangioma: a surgical technique report of two cases

https://doi.org/10.18632/oncotarget.18994

Shaohong Wang, Jun Gao, Mengmeng Yang, Shan Ke, Xuemei Ding, Jian Kong, Li Xu, and Wenbing Sun
52006-52011
Abstract  |  PDF  |  Full Text  |  How to cite


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