Vol 8, No 15

Interaction between the estrogen receptor and fibroblast growth factor receptor pathways in non-small cell lung cancer

Effects of circadian clock genes and environmental factors on cognitive aging in old adults in a Taiwanese population

Azilsartan ameliorates apoptosis of dopaminergic neurons and rescues characteristic parkinsonian behaviors in a rat model of Parkinson’s disease

Serum uric acid level as a cardio-cerebrovascular event risk factor in middle-aged and non-obese Chinese men

Effect of folate deficiency on promoter methylation and gene expression of Esr1, Cav1, and Elavl1, and its influence on spermatogenesis

Transport stress induces weight loss and heart injury in chicks: disruption of ionic homeostasis via modulating ion transporting ATPases

Berberine nanoparticles protects tubular epithelial cells from renal ischemia-reperfusion injury

Vitamin D increases programmed death receptor-1 expression in Crohn’s disease

Suppression of allograft rejection by CD8+CD122+PD-1+ Tregs is dictated by their Fas ligand-initiated killing of effector T cells versus Fas-mediated own apoptosis

Increased expression of ZEB1-AS1 correlates with higher histopathological grade and promotes tumorigenesis in bladder cancer

Early detection of pemetrexed-induced inhibition of thymidylate synthase in non-small cell lung cancer with FLT-PET imaging

Individual patient oesophageal cancer 3D models for tailored treatment

Crosstalk between integrin αvβ3 and ERα contributes to thyroid hormone-induced proliferation of ovarian cancer cells

A clinically feasible multiplex proteomic immunoassay as a novel functional diagnostic for pancreatic ductal adenocarcinoma

Antitumor activity of sulfated hyaluronic acid fragments in pre-clinical models of bladder cancer

LncRNAs are altered in lung squamous cell carcinoma and lung adenocarcinoma

MiR-675-5p supports hypoxia induced epithelial to mesenchymal transition in colon cancer cells

ERCC1-expressing circulating tumor cells as a potential diagnostic tool for monitoring response to platinum-based chemotherapy and for predicting post-therapeutic outcome of ovarian cancer

MiR-124-3p attenuates hyperphosphorylation of Tau protein-induced apoptosis via caveolin-1-PI3K/Akt/GSK3β pathway in N2a/APP695swe cells

The association of pretreatment thrombocytosis with prognosis and clinicopathological significance in cervical cancer: a systematic review and meta-analysis

Hyaluronic acid-serum albumin conjugate-based nanoparticles for targeted cancer therapy

STK31 as novel biomarker of metastatic potential and tumorigenicity of colorectal cancer

Polymorphisms in nucleotide excision repair genes and risk of primary prostate cancer in Chinese Han populations

Squamous cell carcinoma antigen (SCCA) is up-regulated during Barrett’s carcinogenesis and predicts esophageal adenocarcinoma resistance to neoadjuvant chemotherapy

Neutrophil count is associated with myeloid derived suppressor cell level and presents prognostic value for hepatocellular carcinoma patients

Diagnostic and prognostic relevance of CP2c and YY1 expression in hepatocellular carcinoma

Use of Complementary and Alternative Medicine (CAM) in cancer patients: An Italian multicenter survey

Radiosynthesis and validation of (±)-[¹⁸F]-3-fluoro-2-hydroxypropionate ([¹⁸F]-FLac) as a PET tracer of lactate to monitor MCT1-dependent lactate uptake in tumors

NOMO-1 gene is deleted in early-onset colorectal cancer

High CFTR expression in Philadelphia chromosome-positive acute leukemia protects and maintains continuous activation of BCR-ABL and related signaling pathways in combination with PP2A

The long noncoding RNA HOTAIR promotes Parkinson's disease by upregulating LRRK2 expression

Dysadherin specific drug conjugates for the treatment of thyroid cancers with aggressive phenotypes

Nomograms for predicting long-term overall survival and cancer-specific survival in patients with major salivary gland cancer: a population-based study

Jarid2 is essential for the maintenance of tumor initiating cells in bladder cancer

Inhibition of mTORC2 component RICTOR impairs tumor growth in pancreatic cancer models

Pirfenidone normalizes the tumor microenvironment to improve chemotherapy

Epigenetic therapy with inhibitors of histone methylation suppresses DNA damage signaling and increases glioma cell radiosensitivity

A molecular inversion probe-based next-generation sequencing panel to detect germline mutations in Chinese early-onset colorectal cancer patients

Angiotensin-converting enzyme 2 overexpression protects against doxorubicin-induced cardiomyopathy by multiple mechanisms in rats

Non-small cell lung cancer associated microRNA expression signature: integrated bioinformatics analysis, validation and clinical significance

Dose invasive apocrine adenocarcinoma has worse prognosis than invasive ductal carcinoma of breast: evidence from SEER database

Characteristics and comparison of colorectal cancer incidence in Beijing with other regions in the world

Combined MEK and Pi3’-kinase inhibition reveals synergy in targeting thyroid cancer in vitro and in vivo

LMP1⁺SLAMF1^high cells are associated with drug resistance in Epstein-Barr virus-positive Farage cells

The discovery of a novel compound with potent antitumor activity: virtual screening, synthesis, biological evaluation and preliminary mechanism study

PD-L1 expression in perihilar and intrahepatic cholangiocarcinoma

SOCS3 inhibits the pathological effects of IL-22 in non-melanoma skin tumor-derived keratinocytes

MiR-21-5p in urinary extracellular vesicles is a novel biomarker of urothelial carcinoma

EWS-FLI1 confers exquisite sensitivity to NAMPT inhibition in Ewing sarcoma cells

Interferon alpha antagonizes the anti-hepatoma activity of the oncolytic virus M1 by stimulating anti-viral immunity

Cancer-associated oxidoreductase ERO1-α promotes immune escape through up-regulation of PD-L1 in human breast cancer

Lactobacillus casei Zhang and vitamin K2 prevent intestinal tumorigenesis in mice via adiponectin-elevated different signaling pathways

USP22 knockdown enhanced chemosensitivity of hepatocellular carcinoma cells to 5-Fu by up-regulation of Smad4 and suppression of Akt

Glypican-1 targeted antibody-based therapy induces preclinical antitumor activity against esophageal squamous cell carcinoma

Acid ceramidase is a novel drug target for pediatric brain tumors

The oncoprotein gankyrin promotes the development of colitis-associated cancer through activation of STAT3

STAT3 regulates glycolysis via targeting hexokinase 2 in hepatocellular carcinoma cells

Plasmodium parasite as an effective hepatocellular carcinoma antigen glypican-3 delivery vector

Prognostic role of vascular endothelial growth factor in cervical cancer: a meta-analysis

S100A7 promotes lung adenocarcinoma to squamous carcinoma transdifferentiation, and its expression is differentially regulated by the Hippo-YAP pathway in lung cancer cells

Serglycin as a potential biomarker for glioma: association of serglycin expression, extent of mast cell recruitment and glioblastoma progression

Autoantibodies against glucose-regulated protein 78 as serological biomarkers in metastatic and recurrent hepatocellular carcinoma

HIF1/2α mediates hypoxia-induced LDHA expression in human pancreatic cancer cells

NF-κB1, c-Rel, and ELK1 inhibit miR-134 expression leading to TAB1 upregulation in paclitaxel-resistant human ovarian cancer

An autocrine/paracrine circuit of growth differentiation factor (GDF) 15 has a role for maintenance of breast cancer stem-like cells

P21-activated kinase 4 involves TSH induced papillary thyroid cancer cell proliferation

Circulating MIC-1/GDF15 is a complementary screening biomarker with CEA and correlates with liver metastasis and poor survival in colorectal cancer

Precursor N-cadherin mediates glial cell line-derived neurotrophic factor-promoted human malignant glioma

Targeting the stress oncoprotein LEDGF/p75 to sensitize chemoresistant prostate cancer cells to taxanes

The TLR7 agonist imiquimod induces anti-cancer effects via autophagic cell death and enhances anti-tumoral and systemic immunity during radiotherapy for melanoma

Overexpression of miR-29a reduces the oncogenic properties of glioblastoma stem cells by downregulating Quaking gene isoform 6

S100A7 promotes the migration, invasion and metastasis of human cervical cancer cells through epithelial–mesenchymal transition

The mir-675-5p regulates the progression and development of pancreatic cancer via the UBQLN1-ZEB1-mir200 axis

Ribosomal DNA status inferred from DNA cloud assays and mass spectrometry identification of agarose-squeezed proteins interacting with chromatin (ASPIC-MS)

MiR-124 acts as a tumor suppressor by inhibiting the expression of sphingosine kinase 1 and its downstream signaling in head and neck squamous cell carcinoma

Altered amygdala and hippocampus effective connectivity in mild cognitive impairment patients with depression: a resting-state functional MR imaging study with granger causality analysis

Activation of JNK and IRE1 is critically involved in tanshinone I-induced p62 dependent autophagy in malignant pleural mesothelioma cells: implication of p62 UBA domain

Concurrent gene alterations with EGFR mutation and treatment efficacy of EGFR-TKIs in Chinese patients with non-small cell lung cancer

Specific up-regulation of p21 by a small active RNA sequence suppresses human colorectal cancer growth

The combined action of mast cell chymase, tryptase and carboxypeptidase A3 protects against melanoma colonization of the lung

Upregulation of mucin glycoprotein MUC1 in the progression to esophageal adenocarcinoma and therapeutic potential with a targeted photoactive antibody-drug conjugate

Galectin-1 knockdown improves drug sensitivity of breast cancer by reducing P-glycoprotein expression through inhibiting the Raf-1/AP-1 signaling pathway

IRS-2 rs1805097 polymorphism is associated with the decreased risk of colorectal cancer

TMPRSS2:ERG gene fusion variants induce TGF-β signaling and epithelial to mesenchymal transition in human prostate cancer cells

Interleukin-1β levels predict long-term mortality and need for heart transplantation in ambulatory patients affected by idiopathic dilated cardiomyopathy

Suicidal ideation among Chinese cancer inpatients of general hospitals: prevalence and correlates

The inhibiting effect of the transcription factor p53 on dengue virus infection by activating the type I interferon

Akirin2 promotes slow myosin heavy chain expression by CaN/NFATc1 signaling in porcine skeletal muscle satellite cells

Methylation-mediated silencing of microRNA-211 promotes cell growth and epithelial to mesenchymal transition through activation of the AKT/β-catenin pathway in GBM

MMP-3 and MMP-8 single-nucleotide polymorphisms are related to alcohol-induced osteonecrosis of the femoral head in Chinese males

Prognostic value of tumor mutations in radically treated locally advanced non-small cell lung cancer patients

YEATS4 promotes the tumorigenesis of pancreatic cancer by activating beta-catenin/TCF signaling

The aryl hydrocarbon receptor is required for induction of p21^cip1/waf1 expression and growth inhibition by SU5416 in hepatoma cells

A bioartificial dermal regeneration template promotes skin cell proliferation in vitro and enhances large skin wound healing in vivo

Metformin is associated with survival benefit in pancreatic cancer patients with diabetes: a systematic review and meta-analysis

RHBDD1 upregulates EGFR via the AP-1 pathway in colorectal cancer

Peripheral kynurenine/tryptophan ratio is not a reliable marker of systemic indoleamine 2,3-dioxygenase: A lesson drawn from patients on hemodialysis

Genetic polymorphisms of Bcl-2 promoter in cancer susceptibility and prognosis: a meta-analysis

The prognostic value of D-dimer levels in endometrial cancer patients treated with intensity-modulated radiation therapy

Lowered expression of microRNA-125a-5p in human hepatocellular carcinoma and up-regulation of its oncogenic targets sirtuin-7, matrix metalloproteinase-11, and c-Raf

Functional FGFR4 Gly388Arg polymorphism contributes to cancer susceptibility: Evidence from meta-analysis

Oxidative stress-induced apoptosis in granulosa cells involves JNK, p53 and Puma

Epidemiological features of lung giant cell carcinoma and therapy for patients with EGFR mutations based on case reports and the surveillance, epidemiology, and end results (SEER) database

The impacts of single nucleotide polymorphisms in genes of cell cycle and NF-kB pathways on the efficacy and acute toxicities of radiotherapy in patients with nasopharyngeal carcinoma

MiR-148a increases glioma cell migration and invasion by downregulating GADD45A in human gliomas with IDH1 R132H mutations

Paraoxonase 1 gene polymorphisms are associated with an increased risk of breast cancer in a population of Chinese women

Interleukin-22 promotes aerobic glycolysis associated with tumor progression via targeting hexokinase-2 in human colon cancer cells

High BMI1 mRNA expression in peripheral whole blood is associated with favorable prognosis in advanced non-small cell lung cancer patients

Context-dependent miR-204 and miR-211 affect the biological properties of amelanotic and melanotic melanoma cells

The PP4R1 sub-unit of protein phosphatase PP4 is essential for inhibition of NF-κB by merkel polyomavirus small tumour antigen

Human epidermal growth factor receptor 2 expression is more important than Bacillus Calmette Guerin treatment in predicting the outcome of T1G3 bladder cancer

Integrated analysis of promoter methylation and expression of telomere related genes in breast cancer

Clinicopathological features and outcome of chronic lymphocytic leukaemia in Chinese patients

Loss of thyroid hormone receptor interactor 13 inhibits cell proliferation and survival in human chronic lymphocytic leukemia

Mesenchymal stem cells differentially affect the invasion of distinct glioblastoma cell lines

Integrated analysis of genes associated with poor prognosis of patients with colorectal cancer liver metastasis

Vitexin protects against hypoxic-ischemic injury via inhibiting Ca2+/Calmodulin-dependent protein kinase II and apoptosis signaling in the neonatal mouse brain

The soy-derived peptide Lunasin inhibits invasive potential of melanoma initiating cells

Limited impact of intratumour heterogeneity on molecular risk assignment in endometrial cancer

The antidepressant-like effect of trans-astaxanthin involves the serotonergic system

Leukocyte telomere length-related genetic variants in ACYP2 contribute to the risk of esophageal carcinoma in Chinese Han population

Circular RNA hsa-circ-0016347 promotes proliferation, invasion and metastasis of osteosarcoma cells

NOS2 expression in glioma cell lines and glioma primary cell cultures: correlation with neurosphere generation and SOX-2 expression

Global miRNA expression profiling of domestic cat livers following acute Toxoplasma gondii infection

Molecular docking, 3D-QSAR and structural optimization on imidazo-pyridine derivatives dually targeting AT1 and PPARγ

Low CCL-21 expression associates with unfavorable postoperative prognosis of patients with metastatic renal cell carcinoma

Clinical application of 3D-printed-step-bolus in post-total-mastectomy electron conformal therapy

Irinotecan plus cisplatin followed by octreotide long-acting release maintenance treatment in advanced gastroenteropancreatic neuroendocrine carcinoma: IPO-NEC study

Long-term outcomes and propensity score matching analysis: rectal cancer resection for patients with elevated preoperative risk

Emerging role of exosome-mediated intercellular communication in vascular remodeling

Clinical significance of circulating tumor cells in gastric cancer patients

Oncogenic mechanisms of Lin28 in breast cancer: new functions and therapeutic opportunities

Oncogenomic disruptions in arsenic-induced carcinogenesis

Molecular markers of paragangliomas/pheochromocytomas

Opioids: Modulators of angiogenesis in wound healing and cancer

Palliative radiotherapy for gastric cancer: a systematic review and meta-analysis

Repressing CD147 is a novel therapeutic strategy for malignant melanoma

Brain metastases from hepatocellular carcinoma: recent advances and future avenues