Oncotarget

Vol 9, No 27

April 10, 2018

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About The Cover

The cover for issue 27 of Oncotarget features Figure 5, "MYC overexpression in DAOY (YM21) does not alter PD-L1 expression," from Martin, et al.


Table of Contents

Research Papers: Immunology

Tumor cell death after electrotransfer of plasmid DNA is associated with cytosolic DNA sensor upregulation

Tumor cell death after electrotransfer of plasmid DNA is associated with cytosolic DNA sensor upregulation

https://doi.org/10.18632/oncotarget.24816

Katarina Znidar, Masa Bosnjak, Nina Semenova, Olga Pakhomova, Loree Heller,  and Maja Cemazar
18665-18681
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Research Papers

Application of polymersomes engineered to target p32 protein for detection of small breast tumors in mice

Application of polymersomes engineered to target p32 protein for detection of small breast tumors in mice

https://doi.org/10.18632/oncotarget.24588

Lorena Simón-Gracia, Pablo Scodeller, Sergio Salazar Fuentes, Vanessa Gómez Vallejo, Xabier Ríos, Eneko San Sebastián, Valeria Sidorenko, Desirè Di Silvio, Meina Suck, Federica De Lorenzi, Larissa Yokota Rizzo, Saskia von Stillfried, Kalle Kilk, Twan Lammers, Sergio E. Moya,  and Tambet Teesalu
18682-18697
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Consensus molecular subtypes classification of colorectal cancer as a predictive factor for chemotherapeutic efficacy against metastatic colorectal cancer

Consensus molecular subtypes classification of colorectal cancer as a predictive factor for chemotherapeutic efficacy against metastatic colorectal cancer

https://doi.org/10.18632/oncotarget.24617

Akira Okita, Shin Takahashi, Kota Ouchi, Masahiro Inoue, Mika Watanabe, Mareyuki Endo, Hiroshi Honda, Yasuhide Yamada,  and Chikashi Ishioka
18698-18711
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Comprehensive analysis of telomerase inhibition by gallotannin

Comprehensive analysis of telomerase inhibition by gallotannin

https://doi.org/10.18632/oncotarget.24642

Nikita Savelyev, Polina Baykuzina, Svetlana Dokudovskaya, Olga Lavrik, Maria Rubtsova,  and Olga Dontsova
18712-18719
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Pro-tumoral immune cell alterations in wild type and Shb-deficient mice in response to 4T1 breast carcinomas

Pro-tumoral immune cell alterations in wild type and Shb-deficient mice in response to 4T1 breast carcinomas

https://doi.org/10.18632/oncotarget.24643

Xiujuan Li, Kailash Singh, Zhengkang Luo, Mariela Mejia-Cordova, Maria Jamalpour, Björn Lindahl, Ganlin Zhang, Stellan Sandler,  and Michael Welsh
18720-18733
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

BET inhibition is an effective approach against KRAS-driven PDAC and NSCLC

BET inhibition is an effective approach against KRAS-driven PDAC and NSCLC

https://doi.org/10.18632/oncotarget.24648

Toni Jauset, Daniel Massó-Vallés, Sandra Martínez-Martín, Marie-Eve Beaulieu, Laia Foradada, Francesco Paolo Fiorentino, Jun Yokota, Bernard Haendler, Stephan Siegel, Jonathan R. Whitfield,  and Laura Soucek
18734-18746
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Acquired resistance to temsirolimus is associated with integrin α7 driven chemotactic activity of renal cell carcinoma in vitro

Acquired resistance to temsirolimus is associated with integrin α7 driven chemotactic activity of renal cell carcinoma in vitro

https://doi.org/10.18632/oncotarget.24650

Tobias Engl, Jochen Rutz, Sebastian Maxeiner, Sorel Fanguen, Eva Juengel, Sebastian Koschade, Frederik Roos, Wael Khoder, Igor Tsaur,  and Roman A. Blaheta
18747-18759
Abstract  |  PDF  |  HTML  |  Order a Reprint

Synapsin I and Synapsin II regulate neurogenesis in the dentate gyrus of adult mice

Synapsin I and Synapsin II regulate neurogenesis in the dentate gyrus of adult mice

https://doi.org/10.18632/oncotarget.24655

Raffaella Barbieri, Andrea Contestabile, Maria Grazia Ciardo, Nicola Forte, Antonella Marte, Pietro Baldelli, Fabio Benfenati,  and Franco Onofri
18760-18774
Abstract  |  PDF  |  HTML  |  Order a Reprint

Integrated multigene expression panel to prognosticate patients with gastric cancer

Integrated multigene expression panel to prognosticate patients with gastric cancer

https://doi.org/10.18632/oncotarget.24661

Mitsuro Kanda, Kenta Murotani, Haruyoshi Tanaka, Takashi Miwa, Shinichi Umeda, Chie Tanaka, Daisuke Kobayashi, Masamichi Hayashi, Norifumi Hattori, Masaya Suenaga, Suguru Yamada, Goro Nakayama, Michitaka Fujiwara,  and Yasuhiro Kodera
18775-18785
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Findings of multiple HPV genotypes in cervical carcinoma are associated with poor cancer-specific survival in a Swedish cohort of cervical cancer primarily treated with radiotherapy

Findings of multiple HPV genotypes in cervical carcinoma are associated with poor cancer-specific survival in a Swedish cohort of cervical cancer primarily treated with radiotherapy

https://doi.org/10.18632/oncotarget.24666

Malin Kaliff, Bengt Sorbe, Louise Bohr Mordhorst, Gisela Helenius, Mats G. Karlsson,  and Gabriella Lillsunde-Larsson
18786-18796
Abstract  |  PDF  |  HTML  |  Order a Reprint

Does perioperative chemotherapy improve survival in upper tract urothelial carcinoma? A population based analysis

Does perioperative chemotherapy improve survival in upper tract urothelial carcinoma? A population based analysis

https://doi.org/10.18632/oncotarget.24694

Hanan Goldberg, Zachary Klaassen, Thenappan Chandrasekar, Rashid Sayyid, Girish S. Kulkarni, Robert J. Hamilton,  and Neil E. Fleshner
18797-18810
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A phase II trial of 1st-line modified-FOLFOXIRI plus bevacizumab treatment for metastatic colorectal cancer harboring RAS mutation: JACCRO CC-11

A phase II trial of 1st-line modified-FOLFOXIRI plus bevacizumab treatment for metastatic colorectal cancer harboring RAS mutation: JACCRO CC-11

https://doi.org/10.18632/oncotarget.24702

Hironaga Satake, Yu Sunakawa, Yuji Miyamoto, Masato Nakamura, Hiroshi Nakayama, Manabu Shiozawa, Akitaka Makiyama, Kazuma Kobayashi, Yutaro Kubota, Misuzu Mori, Masahito Kotaka, Akinori Takagane, Masahiro Gotoh, Masahiro Takeuchi, Masashi Fujii, Wararu Ichikawa,  and Takashi Sekikawa
18811-18820
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Novel therapeutic features of disulfiram against hepatocellular carcinoma cells with inhibitory effects on a disintegrin and metalloproteinase 10

Novel therapeutic features of disulfiram against hepatocellular carcinoma cells with inhibitory effects on a disintegrin and metalloproteinase 10

https://doi.org/10.18632/oncotarget.24568

Kaku Goto, Jun Arai, Anthony Stephanou,  and Naoya Kato
18821-18831
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Precision cancer therapy: profiting from tumor specific defects in the DNA damage tolerance system

Precision cancer therapy: profiting from tumor specific defects in the DNA damage tolerance system

https://doi.org/10.18632/oncotarget.24777

Olimpia Alessandra Buoninfante, Bas Pilzecker, Muhammad Assad Aslam, Ioannis Zavrakidis, Rianne van der Wiel, Marieke van de Ven, Paul C.M. van den Berk,  and Heinz Jacobs
18832-18843
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Isolated metastasis of an EGFR-L858R-mutated NSCLC of the meninges: the potential impact of CXCL12/CXCR4 axis in EGFRmut NSCLC in diagnosis, follow-up and treatment

Isolated metastasis of an EGFR-L858R-mutated NSCLC of the meninges: the potential impact of CXCL12/CXCR4 axis in EGFRmut NSCLC in diagnosis, follow-up and treatment

https://doi.org/10.18632/oncotarget.24787

Florian Lüke, Raquel Blazquez, Rezan Fahrioglu Yamaci, Xin Lu, Benedikt Pregler, Stefan Hannus, Karin Menhart, Dirk Hellwig, Hans-Jürgen Wester, Saskia Kropf, Daniel Heudobler, Jirka Grosse, Jutta Moosbauer, Markus Hutterer, Peter Hau, Markus J. Riemenschneider, Michaela Bayerlová, Annalen Bleckmann, Bernhard Polzer, Tim Beißbarth, Christoph A. Klein,  and Tobias Pukrop
18844-18857
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Glycine: a non-invasive imaging biomarker to aid magnetic resonance spectroscopy in the prediction of survival in paediatric brain tumours

Glycine: a non-invasive imaging biomarker to aid magnetic resonance spectroscopy in the prediction of survival in paediatric brain tumours

https://doi.org/10.18632/oncotarget.24789

Ben Babourina-Brooks, Sarah Kohe, Simrandip K. Gill, Lesley MacPherson, Martin Wilson, Nigel P. Davies,  and Andrew C. Peet
18858-18868
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Recruitment of mitofusin 2 into “lipid rafts” drives mitochondria fusion induced by Mdivi-1

Recruitment of mitofusin 2 into “lipid rafts” drives mitochondria fusion induced by Mdivi-1

https://doi.org/10.18632/oncotarget.24792

Laura Ciarlo, Rosa Vona, Valeria Manganelli, Lucrezia Gambardella, Carla Raggi, Matteo Marconi, Walter Malorni, Maurizio Sorice, Tina Garofalo,  and Paola Matarrese
18869-18884
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Differentiation-inducing therapeutic effect of Notch inhibition in reversing malignant transformation of liver normal stem cells via MET

Differentiation-inducing therapeutic effect of Notch inhibition in reversing malignant transformation of liver normal stem cells via MET

https://doi.org/10.18632/oncotarget.24421

Hao Luo, Wei-Hui Liu, Hong-Yin Liang, Hong-Tao Yan, Ning Lin, Dong-Yu Li, Tao Wang,  and Li-Jun Tang
18885-18895
Abstract  |  PDF  |  HTML  |  Order a Reprint

DNMT1 ablation suppresses tumorigenesis by inhibiting the self-renewal of esophageal cancer stem cells

DNMT1 ablation suppresses tumorigenesis by inhibiting the self-renewal of esophageal cancer stem cells

https://doi.org/10.18632/oncotarget.24116

Ying Teng, Xiying Yu, Hui Yuan, Liping Guo, Wei Jiang,  and Shih-Hsin Lu
18896-18907
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Assessment of the Palliative Prognostic Index in hospitalized oncologic patients treated by a palliative care team: impact of acute concomitant diseases

Assessment of the Palliative Prognostic Index in hospitalized oncologic patients treated by a palliative care team: impact of acute concomitant diseases

https://doi.org/10.18632/oncotarget.24826

Carmen Palomar-Muñoz, Marina Martín-Zamorano, Amparo Mogollo, Susana Pascual-Pérez, Inmaculada Rodríguez-Morales,  and José-Antonio Girón-González
18908-18915
Abstract  |  PDF  |  HTML  |  Order a Reprint

Loss of nuclear NOTCH1, but not its negative regulator NUMB, is an independent predictor of cervical malignancy

Loss of nuclear NOTCH1, but not its negative regulator NUMB, is an independent predictor of cervical malignancy

https://doi.org/10.18632/oncotarget.24828

Elenaé Vázquez-Ulloa, Ana Clara Ramos-Cruz, Diddier Prada, Alejandro Avilés-Salas, Alma Delia Chávez-Blanco, Luis A. Herrera, Marcela Lizano,  and Adriana Contreras-Paredes
18916-18928
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Salivary microRNAs as new molecular markers in cleft lip and palate: a new frontier in molecular medicine

Salivary microRNAs as new molecular markers in cleft lip and palate: a new frontier in molecular medicine

https://doi.org/10.18632/oncotarget.24838

Vincenzo Grassia, Angela Lombardi, Hiromichi Kawasaki, Carmela Ferri, Letizia Perillo, Laura Mosca, Donatella Delle Cave, Ludovica Nucci, Marina Porcelli,  and Michele Caraglia
18929-18938
Abstract  |  PDF  |  HTML  |  Order a Reprint

Epigenetic hypomethylation and upregulation of NLRC4 and NLRP12 in Kawasaki disease

Epigenetic hypomethylation and upregulation of NLRC4 and NLRP12 in Kawasaki disease

https://doi.org/10.18632/oncotarget.24851

Ying-Hsien Huang, Mao-Hung Lo, Xin-Yuan Cai,  and Ho-Chang Kuo
18939-18948
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The decrease of glycolytic enzyme hexokinase 1 accelerates tumor malignancy via deregulating energy metabolism but sensitizes cancer cells to 2-deoxyglucose inhibition

The decrease of glycolytic enzyme hexokinase 1 accelerates tumor malignancy via deregulating energy metabolism but sensitizes cancer cells to 2-deoxyglucose inhibition

https://doi.org/10.18632/oncotarget.24855

Po-Lin Tseng, Chih-Wei Chen, Keng-Hsun Hu, Hung-Chi Cheng, Yuan-Ho Lin, Wen-Hui Tsai, Tain-Junn Cheng, Wei-Hsuan Wu, Chin-Wei Yeh, Chin-Chih Lin, Hui-Ju Tsai, Hao-Chun Chang, Jiin-Haur Chuang, Yan-Shen Shan,  and Wen-Tsan Chang
18949-18969
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pretreatment monocyte counts and neutrophil counts predict the risk for febrile neutropenia in patients undergoing TPF chemotherapy for head and neck squamous cell carcinoma

Pretreatment monocyte counts and neutrophil counts predict the risk for febrile neutropenia in patients undergoing TPF chemotherapy for head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.24863

Marie Shimanuki, Yorihisa Imanishi, Yoichiro Sato, Nana Nakahara, Daisuke Totsuka, Emiri Sato, Sena Iguchi, Yasuo Sato, Keiko Soma, Yasutomo Araki, Seiji Shigetomi, Satoko Yoshida, Kosuke Uno, Yusuke Ogawa, Takehiro Tominaga, Yuichi Ikari, Junko Nagayama, Ayako Endo, Koshiro Miura, Takuya Tomioka, Hiroyuki Ozawa,  and Kaoru Ogawa
18970-18984
Abstract  |  PDF  |  HTML  |  Order a Reprint

A pilot study of durvalumab and tremelimumab and immunogenomic dynamics in metastatic breast cancer

A pilot study of durvalumab and tremelimumab and immunogenomic dynamics in metastatic breast cancer

https://doi.org/10.18632/oncotarget.24867

Cesar August Santa-Maria, Taigo Kato, Jae-Hyun Park, Kazuma Kiyotani, Alfred Rademaker, Ami N. Shah, Leeaht Gross, Luis Z. Blanco, Sarika Jain, Lisa Flaum, Claudia Tellez, Regina Stein, Regina Uthe, William J. Gradishar, Massimo Cristofanilli, Yusuke Nakamura,  and Francis J. Giles
18985-18996
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) is a novel marker for patients with BRAF-mutated metastatic melanoma

Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) is a novel marker for patients with BRAF-mutated metastatic melanoma

https://doi.org/10.18632/oncotarget.24871

Valentina Audrito, Antonella Managò, Federica Zamporlini, Eliana Rulli, Federica Gaudino, Gabriele Madonna, Stefania D'Atri, Gian Carlo Antonini Cappellini, Paolo Antonio Ascierto, Daniela Massi, Nadia Raffaelli, Mario Mandalà,  and Silvia Deaglio
18997-19005
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Glypican-1 is enriched in circulating-exosomes in pancreatic cancer and correlates with tumor burden

Glypican-1 is enriched in circulating-exosomes in pancreatic cancer and correlates with tumor burden

https://doi.org/10.18632/oncotarget.24873

Adam E. Frampton, Mireia Mato Prado, Elena López-Jiménez, Ana Belen Fajardo-Puerta, Zaynab A.R. Jawad, Phillip Lawton, Elisa Giovannetti, Nagy A. Habib, Leandro Castellano, Justin Stebbing, Jonathan Krell,  and Long R. Jiao
19006-19013
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miRNA expression profile of bone marrow resident cells from children with neuroblastoma is not significantly different from that of healthy children

miRNA expression profile of bone marrow resident cells from children with neuroblastoma is not significantly different from that of healthy children

https://doi.org/10.18632/oncotarget.24874

Sara Stigliani, Fabio Morandi, Luca Persico, Corrado Lagazio, Giovanni Erminio, Paola Scaruffi,  and Maria Valeria Corrias
19014-19025
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Near infrared photoimmunotherapy targeting bladder cancer with a canine anti-epidermal growth factor receptor (EGFR) antibody

Near infrared photoimmunotherapy targeting bladder cancer with a canine anti-epidermal growth factor receptor (EGFR) antibody

https://doi.org/10.18632/oncotarget.24876

Tadanobu Nagaya, Shuhei Okuyama, Fusa Ogata, Yasuhiro Maruoka, Deborah W. Knapp, Sophia N. Karagiannis, Judit Fazekas-Singer, Peter L. Choyke, Amy K. LeBlanc, Erika Jensen-Jarolim,  and Hisataka Kobayashi
19026-19038
Abstract  |  PDF  |  HTML  |  Order a Reprint

Crosstalk between Akt signaling and cold shock proteins in mediating invasive cell phenotypes

Crosstalk between Akt signaling and cold shock proteins in mediating invasive cell phenotypes

https://doi.org/10.18632/oncotarget.24886

Raphael Hohlfeld, Sabine Brandt, Anja Bernhardt, Xenia Gorny, Daniel Schindele, Burkhard Jandrig, Martin Schostak, Berend Isermann, Jonathan A. Lindquist,  and Peter R. Mertens
19039-19049
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Delineating the HMGB1 and HMGB2 interactome in prostate and ovary epithelial cells and its relationship with cancer

Delineating the HMGB1 and HMGB2 interactome in prostate and ovary epithelial cells and its relationship with cancer

https://doi.org/10.18632/oncotarget.24887

Aida Barreiro-Alonso, Mónica Lamas-Maceiras, Rosa García-Díaz, Esther Rodríguez-Belmonte, Lu Yu, Mercedes Pardo, Jyoti S. Choudhary,  and María Esperanza Cerdán
19050-19064
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Correlation between lower balance of Th2 helper T-cells and expression of PD-L1/PD-1 axis genes enables prognostic prediction in patients with glioblastoma

Correlation between lower balance of Th2 helper T-cells and expression of PD-L1/PD-1 axis genes enables prognostic prediction in patients with glioblastoma

https://doi.org/10.18632/oncotarget.24897

Yasuo Takashima, Atsushi Kawaguchi, Tomohiko Kanayama, Azusa Hayano,  and Ryuya Yamanaka
19065-19078
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

An epigenetic regulator-related score (EpiScore) predicts survival in patients with diffuse large B cell lymphoma and identifies patients who may benefit from epigenetic therapy

An epigenetic regulator-related score (EpiScore) predicts survival in patients with diffuse large B cell lymphoma and identifies patients who may benefit from epigenetic therapy

https://doi.org/10.18632/oncotarget.24901

Vanessa Szablewski, Caroline Bret, Alboukadel Kassambara, Julie Devin, Guillaume Cartron, Valérie Costes-Martineau,  and Jérôme Moreaux
19079-19099
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Myofibroblast androgen receptor expression determines cell survival in co-cultures of myofibroblasts and prostate cancer cells in vitro

Myofibroblast androgen receptor expression determines cell survival in co-cultures of myofibroblasts and prostate cancer cells in vitro

https://doi.org/10.18632/oncotarget.24913

Helen M. Palethorpe, Damien A. Leach, Eleanor F. Need, Paul A. Drew,  and Eric Smith
19100-19114
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Total lesion glycolysis on FDG-PET/CT before salvage surgery predicts survival in laryngeal or pharyngeal cancer

Total lesion glycolysis on FDG-PET/CT before salvage surgery predicts survival in laryngeal or pharyngeal cancer

https://doi.org/10.18632/oncotarget.24914

Hidenori Suzuki, Tsuneo Tamaki, Masami Nishio, Yusuke Nakata, Nobuhiro Hanai, Daisuke Nishikawa, Yusuke Koide,  and Yasuhisa Hasegawa
19115-19122
Abstract  |  PDF  |  HTML  |  Order a Reprint

Hypoxia-inducible factor-2 alpha up-regulates CD70 under hypoxia and enhances anchorage-independent growth and aggressiveness in cancer cells

Hypoxia-inducible factor-2 alpha up-regulates CD70 under hypoxia and enhances anchorage-independent growth and aggressiveness in cancer cells

https://doi.org/10.18632/oncotarget.24919

Shojiro Kitajima, Kian Leong Lee, Masaki Fujioka, Wendi Sun, Jia You, Grace Sushin Chia, Hideki Wanibuchi, Shuhei Tomita, Marito Araki, Hiroyuki Kato,  and Lorenz Poellinger
19123-19135
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Assessment of micro RNAs expression in leukemic cells as prognostic markers in chronic lymphocytic leukemia: micro RNAs can predict survival in a course of the disease

Assessment of micro RNAs expression in leukemic cells as prognostic markers in chronic lymphocytic leukemia: micro RNAs can predict survival in a course of the disease

https://doi.org/10.18632/oncotarget.24927

Agnieszka Szymczyk, Sylwia Chocholska, Arkadiusz Macheta, Dariusz Szczepanek, Marek Hus,  and Monika Podhorecka
19136-19146
Abstract  |  PDF  |  HTML  |  Order a Reprint

CD200fc enhances anti-tumoral immune response and inhibits visceral metastasis of breast carcinoma

CD200fc enhances anti-tumoral immune response and inhibits visceral metastasis of breast carcinoma

https://doi.org/10.18632/oncotarget.24931

Nuray Erin, Gamze Tanrıöver, Anna Curry, Muhlis Akman, Özlem Duymuş,  and Reg Gorczynski
19147-19158
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-652 induces NED in LNCaP and EMT in PC3 prostate cancer cells

MicroRNA-652 induces NED in LNCaP and EMT in PC3 prostate cancer cells

https://doi.org/10.18632/oncotarget.24937

Robert K. Nam, Tania Benatar, Yutaka Amemiya, Christopher J.D. Wallis, Joan Miguel Romero, Melina Tsagaris, Christopher Sherman, Linda Sugar,  and Arun Seth
19159-19176
Abstract  |  PDF  |  HTML  |  Order a Reprint

PD-L1 expression in medulloblastoma: an evaluation by subgroup

PD-L1 expression in medulloblastoma: an evaluation by subgroup

https://doi.org/10.18632/oncotarget.24951

Allison M. Martin, Christopher J. Nirschl, Magda J. Polanczyk, W. Robert Bell, Thomas R. Nirschl, Sarah Harris-Bookman, Jillian Phallen, Jessica Hicks, Daniel Martinez, Aleksandra Ogurtsova, Haiying Xu, Lisa M. Sullivan, Alan K. Meeker, Eric H. Raabe, Kenneth J. Cohen, Charles G. Eberhart, Peter C. Burger, Mariarita Santi, Janis M. Taube, Drew M. Pardoll, Charles G. Drake,  and Michael Lim
19177-19191
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Impact of pigment epithelium-derived factor on colorectal cancer in vitro and in vivo

Impact of pigment epithelium-derived factor on colorectal cancer in vitro and in vivo

https://doi.org/10.18632/oncotarget.24953

Rhiannon L. Harries, Sioned Owen, Fiona Ruge, Meleri Morgan, Jun Li, Zhangtao Zhang, Keith G. Harding, Jared Torkington, Wen G. Jiang,  and Jun Cai
19192-19202
Abstract  |  PDF  |  HTML  |  Order a Reprint

Identification of an EPC2-PHF1 fusion transcript in low-grade endometrial stromal sarcoma

Identification of an EPC2-PHF1 fusion transcript in low-grade endometrial stromal sarcoma

https://doi.org/10.18632/oncotarget.24969

Marta Brunetti, Ludmila Gorunova, Ben Davidson, Sverre Heim, Ioannis Panagopoulos,  and Francesca Micci
19203-19208
Abstract  |  PDF  |  HTML  |  Order a Reprint

Myoferlin regulates epithelial cancer cell plasticity and migration through autocrine TGF-β1 signaling

Myoferlin regulates epithelial cancer cell plasticity and migration through autocrine TGF-β1 signaling

https://doi.org/10.18632/oncotarget.24971

Victoria R. Barnhouse, Jessica L. Weist, Vasudha C. Shukla, Samir N. Ghadiali, Douglas A. Kniss,  and Jennifer L. Leight
19209-19222
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Comprehensive genomic transcriptomic tumor-normal gene panel analysis for enhanced precision in patients with lung cancer

Comprehensive genomic transcriptomic tumor-normal gene panel analysis for enhanced precision in patients with lung cancer

https://doi.org/10.18632/oncotarget.24973

Shahrooz Rabizadeh, Chad Garner, John Zachary Sanborn, Stephen C. Benz, Sandeep Reddy,  and Patrick Soon-Shiong
19223-19232
Abstract  |  PDF  |  HTML  |  Order a Reprint

Backtracked analysis of preleukemic fusion genes and DNA repair foci in umbilical cord blood of children with acute leukemia

Backtracked analysis of preleukemic fusion genes and DNA repair foci in umbilical cord blood of children with acute leukemia

https://doi.org/10.18632/oncotarget.24976

Milan Škorvaga, Matúš Durdík, Pavol Košík, Eva Marková, Marek Holop, Miroslav Kubeš, Judita Puškáčová, Alexandra Kolenová,  and Igor Belyaev
19233-19244
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Global burden of neuroendocrine tumors and changing incidence in Kentucky

Global burden of neuroendocrine tumors and changing incidence in Kentucky

https://doi.org/10.18632/oncotarget.24983

Aman Chauhan, Qian Yu, Neha Ray, Zainab Farooqui, Bin Huang, Eric B. Durbin, Thomas Tucker, Mark Evers, Susanne Arnold,  and Lowell B. Anthony
19245-19254
Abstract  |  PDF  |  HTML  |  Order a Reprint

Rapid methods to create a positive control and identify the PAX8/PPARγ rearrangement in FNA thyroid samples by molecular biology

Rapid methods to create a positive control and identify the PAX8/PPARγ rearrangement in FNA thyroid samples by molecular biology

https://doi.org/10.18632/oncotarget.24995

Emilia Vuttariello, Elio Biffali, Raimondo Pannone, Anna Capiluongo, Mario Monaco, Valentina Sica, Concetta Aiello, Marco Matuozzo, Maria Grazia Chiofalo, Gerardo Botti,  and Gennaro Chiappetta
19255-19262
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Recombinant methioninase combined with doxorubicin (DOX) regresses a DOX-resistant synovial sarcoma in a patient-derived orthotopic xenograft (PDOX) mouse model

Recombinant methioninase combined with doxorubicin (DOX) regresses a DOX-resistant synovial sarcoma in a patient-derived orthotopic xenograft (PDOX) mouse model

https://doi.org/10.18632/oncotarget.24996

Kentaro Igarashi, Kei Kawaguchi, Shukuan Li, Qinghong Han, Yuying Tan, Emily Gainor, Tasuku Kiyuna, Kentaro Miyake, Masuyo Miyake, Takashi Higuchi, Hiromichi Oshiro, Arun S. Singh, Mark A. Eckardt, Scott D. Nelson, Tara A. Russell, Sarah M. Dry, Yunfeng Li, Norio Yamamoto, Katsuhiro Hayashi, Hiroaki Kimura, Shinji Miwa, Hiroyuki Tsuchiya, Fritz C. Eilber,  and Robert M. Hoffman
19263-19272
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Antitumor efficacy of Kisspeptin in human malignant mesothelioma cells

Antitumor efficacy of Kisspeptin in human malignant mesothelioma cells

https://doi.org/10.18632/oncotarget.25018

Vincenza Ciaramella, Carminia Maria Della Corte, Concetta Di Mauro, Stefano Tomassi, Salvatore Di Maro, Teresa Troiani, Erika Martinelli, Roberto Bianco, Sandro Cosconati, Riccardo Pierantoni, Rosaria Meccariello, Rosanna Chianese, Fortunato Ciardiello,  and Floriana Morgillo
19273-19282
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Circulating tumor cells, tumor-derived extracellular vesicles and plasma cytokeratins in castration-resistant prostate cancer patients

Circulating tumor cells, tumor-derived extracellular vesicles and plasma cytokeratins in castration-resistant prostate cancer patients

https://doi.org/10.18632/oncotarget.25019

Afroditi Nanou, Frank A.W. Coumans, Guus van Dalum, Leonie L. Zeune, David Dolling, Wendy Onstenk, Mateus Crespo, Mariane Sousa Fontes, Pasquale Rescigno, Gemma Fowler, Penny Flohr, Christoph Brune, Stefan Sleijfer, Johann S. de Bono,  and Leon W.M.M. Terstappen
19283-19293
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Patient derived xenografts (PDX) predict an effective heparanase-based therapy for lung cancer

Patient derived xenografts (PDX) predict an effective heparanase-based therapy for lung cancer

https://doi.org/10.18632/oncotarget.25022

Amit Katz, Uri Barash, Ilanit Boyango, Sari Feld, Yaniv Zohar, Edward Hammond, Neta Ilan, Ran Kremer,  and Israel Vlodavsky
19294-19306
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Comparison and evaluation of two RGD peptides labelled with 68Ga or 18F for PET imaging of angiogenesis in animal models of human glioblastoma or lung carcinoma

Comparison and evaluation of two RGD peptides labelled with 68Ga or 18F for PET imaging of angiogenesis in animal models of human glioblastoma or lung carcinoma

https://doi.org/10.18632/oncotarget.25028

Claire Provost, Aurélie Prignon, Laura Rozenblum-Beddok, Quentin Bruyer, Sylvie Dumont, Fatiha Merabtene, Valérie Nataf, Cédric Bouteiller,  and Jean-Noël Talbot
19307-19316
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Treosulfan induces distinctive gonadal toxicity compared with busulfan

Treosulfan induces distinctive gonadal toxicity compared with busulfan

https://doi.org/10.18632/oncotarget.25029

Mattan Levi, Salomon M. Stemmer, Jerry Stein, Ruth Shalgi,  and Irit Ben-Aharon
19317-19327
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Stress and stem cells: adult Muse cells tolerate extensive genotoxic stimuli better than mesenchymal stromal cells

Stress and stem cells: adult Muse cells tolerate extensive genotoxic stimuli better than mesenchymal stromal cells

https://doi.org/10.18632/oncotarget.25039

Nicola Alessio, Tiziana Squillaro, Servet Özcan, Giovanni Di Bernardo, Massimo Venditti, Mariarosa Melone, Gianfranco Peluso,  and Umberto Galderisi
19328-19341
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Impact of mutational studies on the diagnosis and the outcome of high-risk myelodysplastic syndromes and secondary acute myeloid leukemia patients treated with 5-azacytidine

Impact of mutational studies on the diagnosis and the outcome of high-risk myelodysplastic syndromes and secondary acute myeloid leukemia patients treated with 5-azacytidine

https://doi.org/10.18632/oncotarget.25046

Marta Cabezón, Joan Bargay, Blanca Xicoy, Olga García, Josep Borrás, Mar Tormo, Sílvia Marcé, Carme Pedro, David Valcárcel, Maria-José Jiménez, Ramón Guàrdia, Laura Palomo, Salut Brunet, Ferran Vall-Llovera, Antoni Garcia, Evarist Feliu,  and Lurdes Zamora On Behalf of the CETLAM Group
19342-19355
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Circulating and tumor-associated caspase-4: a novel diagnostic and prognostic biomarker for non-small cell lung cancer

Circulating and tumor-associated caspase-4: a novel diagnostic and prognostic biomarker for non-small cell lung cancer

https://doi.org/10.18632/oncotarget.25049

Michela Terlizzi, Chiara Colarusso, Ilaria De Rosa, Nicolina De Rosa, Pasquale Somma, Carlo Curcio, Alessandro Zamparelli Sanduzzi, Pietro Micheli, Antonio Molino, Antonello Saccomanno, Rosario Salvi, Rita P. Aquino, Aldo Pinto,  and Rosalinda Sorrentino
19356-19367
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Radiotherapy increases plasma levels of tumoral cell-free DNA in non-small cell lung cancer patients

Radiotherapy increases plasma levels of tumoral cell-free DNA in non-small cell lung cancer patients

https://doi.org/10.18632/oncotarget.25053

Shun-Ichiro Kageyama, Keiji Nihei, Katsuyuki Karasawa, Takeshi Sawada, Fumiaki Koizumi, Shigeo Yamaguchi, Shunsuke Kato, Hidehiro Hojo, Atsuhi Motegi, Katsuya Tsuchihara,  and Tetsuo Akimoto
19368-19378
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Treatment with epigenetic agents profoundly inhibits tumor growth in leiomyosarcoma

Treatment with epigenetic agents profoundly inhibits tumor growth in leiomyosarcoma

https://doi.org/10.18632/oncotarget.25056

Cynthia De Carvalho Fischer, Yue Hu, Michael Morreale, Wan Ying Lin, Akhil Wali, Maya Thakar, Enusha Karunasena, Rupashree Sen, Yi Cai, Lauren Murphy, Cynthia A. Zahnow, Harold Keer, Manjusha Thakar,  and Nita Ahuja
19379-19395
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Meta-Analysis

Advanced pancreatic cancer: a meta-analysis of clinical trials over thirty years

Advanced pancreatic cancer: a meta-analysis of clinical trials over thirty years

https://doi.org/10.18632/oncotarget.25036

Bradley R. Hall, Andrew Cannon, Pranita Atri, Christopher S. Wichman, Lynette M. Smith, Apar K. Ganti, Chandrakanth Are, Aaron R. Sasson, Sushil Kumar,  and Surinder K. Batra
19396-19405
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Efficacy and safety of sorafenib for advanced renal cell carcinoma: real-world data of patients with renal impairment

Efficacy and safety of sorafenib for advanced renal cell carcinoma: real-world data of patients with renal impairment

https://doi.org/10.18632/oncotarget.24779

Katsunori Tatsugami, Mototsugu Oya, Koki Kabu,  and Hideyuki Akaza
19406-19414
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Reviews

Anabolic androgenic steroids and carcinogenicity focusing on Leydig cell: a literature review

Anabolic androgenic steroids and carcinogenicity focusing on Leydig cell: a literature review

https://doi.org/10.18632/oncotarget.24767

Monica Salerno, Orazio Cascio, Giuseppe Bertozzi, Francesco Sessa, Antonietta Messina, Vincenzo Monda, Luigi Cipolloni, Antonio Biondi, Aurora Daniele,  and Cristoforo Pomara
19415-19426
Abstract  |  PDF  |  HTML  |  Order a Reprint

Distinct molecular subtypes of gastric cancer: from Laurén to molecular pathology

Distinct molecular subtypes of gastric cancer: from Laurén to molecular pathology

https://doi.org/10.18632/oncotarget.24827

Magdalena Cisło, Agata Anna Filip, George Johan Arnold Offerhaus, Bogumiła Ciseł, Karol Rawicz-Pruszyński, Małgorzata Skierucha,  and Wojciech Piotr Polkowski
19427-19442
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Epigenetic regulation of long non-coding RNAs in gastric cancer

Epigenetic regulation of long non-coding RNAs in gastric cancer

https://doi.org/10.18632/oncotarget.23821

Zhixia Zhou, Zhijuan Lin, Xin Pang, Muhammad Akram Tariq, Xiang Ao, Peifeng Li,  and Jianxun Wang
19443-19458
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Corrections

Correction: Niclosamide and its analogs are potent inhibitors of Wnt/β-catenin, mTOR and STAT3 signaling in ovarian cancer

Correction: Niclosamide and its analogs are potent inhibitors of Wnt/β-catenin, mTOR and STAT3 signaling in ovarian cancer

https://doi.org/10.18632/oncotarget.25151

Rebecca C. Arend, Angelina I. Londoño-Joshi, Abhishek Gangrade, Ashwini A. Katre, Chandrika Kurpad, Yonghe Li, Rajeev S. Samant, Pui-Kai Li, Charles N. Landen, Eddy S. Yang, Bertha Hidalgo, Ronald D. Alvarez, John Michael Straughn, Andres Forero,  and Donald J. Buchsbaum
19459-19459
Correction  |  PDF

Correction: Role of novel histone modifications in cancer

Correction: Role of novel histone modifications in cancer

https://doi.org/10.18632/oncotarget.25152

Muthu K. Shanmugam, Frank Arfuso, Surendar Arumugam, Arunachalam Chinnathambi, Jinsong Bian, Sudha Warrier, Ling Zhi Wang, Alan Prem Kumar, Kwang Seok Ahn, Gautam Sethi,  and Manikandan Lakshmanan
19460-19460
Correction  |  PDF


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