Inhibition of the NEDD8 conjugation pathway induces calcium-dependent compensatory activation of the pro-survival MEK/ERK pathway in acute lymphoblastic leukemia

Regulation of E-cadherin localization by microtubule targeting agents: rapid promotion of cortical E-cadherin through p130CAS/Src inhibition by eribulin

The involvement of serum exosomal miR-500-3p and miR-770-3p in aging: modulation by calorie restriction

MMP2-A2M interaction increases ECM accumulation in aged rat kidney and its modulation by calorie restriction

Association of serum levels of antibodies against MMP1, CBX1, and CBX5 with transient ischemic attack and cerebral infarction

Anticoagulants inhibit proteolytic clearance of plasma amyloid beta

NAB2 is a novel immune stimulator of MDA-5 that promotes a strong type I interferon response

Microsatellite instability is a biomarker for immune checkpoint inhibitors in endometrial cancer

Combining molecular and immunohistochemical analyses of key drivers in primary melanomas: interplay between germline and somatic variations

Consecutive epigenetically-active agent combinations act in ID1-RUNX3-TET2 and HOXA pathways for Flt3ITD+ve AML

The protein kinase SIK downregulates the polarity protein Par3

Under-expression of CK2β subunit in ccRCC represents a complementary biomarker of p-STAT3 Ser727 that correlates with patient survival

Phospholipase Cγ1 links inflammation and tumorigenesis in colitis-associated cancer

Stroma-derived extracellular vesicles deliver tumor-suppressive miRNAs to pancreatic cancer cells

Long-term prediction of prostate cancer diagnosis and death using PSA and obesity related anthropometrics at early middle age: data from the malmö preventive project

Analysis of the circular RNA transcriptome in endometrial cancer

Upregulation of cell cycle genes in head and neck cancer patients may be antagonized by erufosine's down regulation of cell cycle processes in OSCC cells

Breast cancer stem cells in HER2-negative breast cancer cells contribute to HER2-mediated radioresistance and molecular subtype conversion: clinical implications for serum HER2 in recurrent HER2-negative breast cancer

Comparison of the modified low-dose cytarabine and etoposide with decitabine therapy for elderly acute myeloid leukemia patients unfit for intensive chemotherapy

The influence of chemotherapy on adenosine-producing B cells in patients with head and neck squamous cell carcinoma

High RAC3 expression levels are required for induction and maintaining of cancer cell stemness

Activation of Grm1 expression by mutated BRaf (V600E) in vitro and in vivo

Inhibition of NF-κB prevents the acidic bile-induced oncogenic mRNA phenotype, in human hypopharyngeal cells

YAP-associated chromosomal instability and cholangiocarcinoma in mice

Zinc finger protein 598 inhibits cell survival by promoting UV-induced apoptosis

The transcriptional and mutational landscapes of lipid metabolism-related genes in colon cancer

Pathological and functional significance of Semaphorin-5A in pancreatic cancer progression and metastasis

Identification and characterization of novel enhanced cell penetrating peptides for anti-cancer cargo delivery

A dock derived compound against laminin receptor (37 LR) exhibits anti-cancer properties in a prostate cancer cell line model

Src is the primary target of aripiprazole, an atypical antipsychotic drug, in its anti-tumor action

Inhibition of IAP’s and activation of p53 leads to caspase-dependent apoptosis in gastric cancer cells treated with Scutellarein

Assessing tumor molecular profiling to guide treatments for patients with advanced female genital tract malignancy

Human papillomavirus E7 oncoprotein expression by keratinocytes alters the cytotoxic mechanisms used by CD8 T cells

Epigenetic changes found in uterine decidual and placental tissues can also be found in the breast cancer microenvironment of the same unique patient: description and potential interpretations

Combination of a thioxodihydroquinazolinone with cisplatin eliminates ovarian cancer stem cell-like cells (CSC-LCs) and shows preclinical potential

Rapid development of myeloproliferative neoplasm in mice with Ptpn11^D61Y mutation and haploinsufficient for Dnmt3a

[Neratinib + Valproate] exposure permanently reduces ERBB1 and RAS expression in 4T1 mammary tumors and enhances M1 macrophage infiltration

Expression of Wnt-signaling pathway genes and their associations with miRNAs in colorectal cancer

Construction of key signal regulatory network in metastatic colorectal cancer

Type IIB DNA topoisomerase is downregulated by trastuzumab and doxorubicin to synergize cardiotoxicity

Characterization and metabolic synthetic lethal testing in a new model of SDH-loss familial pheochromocytoma and paraganglioma

Drp1/Fis1 interaction mediates mitochondrial dysfunction, bioenergetic failure and cognitive decline in Alzheimer's disease

Natural and molecular history of prolactinoma: insights from a Prlr^–/– mouse model

Cell-cell fusion as a mechanism of DNA exchange in cancer

Combined inhibition of CDK and HDAC as a promising therapeutic strategy for both cutaneous and uveal metastatic melanoma

Translational study reveals a two-faced role of RBM3 in pancreatic cancer and suggests its potential value as a biomarker for improved patient stratification

The presence of PD-1 positive tumor infiltrating lymphocytes in triple negative breast cancers is associated with a favorable outcome of disease

Near infrared fluorescence imaging of EGFR expression in vivo using IRDye800CW-nimotuzumab

Gene aberration profile of tumors of adolescent and young adult females

Prognostic significance of heparanase expression in primary and metastatic breast carcinoma

Determination of candidate metabolite biomarkers associated with recurrence of HCV-related hepatocellular carcinoma

2-Amino-3-methylcarboxy-5-heptyl-thiophene (TJ191) is a selective anti-cancer small molecule that targets low TβRIII-expressing malignant T-cell leukemia/lymphoma cells

Activation of p53 and destabilization of androgen receptor by combinatorial inhibition of MDM2 and MDMX in prostate cancer cells

LIMD1 is induced by and required for LMP1 signaling, and protects EBV-transformed cells from DNA damage-induced cell death

The possible existence of occult metastasis in patients with ovarian clear-cell carcinoma who underwent complete resection without any residual tumours

A lethal synergy induced by phellinus linteus and camptothecin11 in colon cancer cells

Interleukin 8 activity influences the efficacy of adenoviral oncolytic immunotherapy in cancer patients

Quantitative radiomic profiling of glioblastoma represents transcriptomic expression

Complement C4d-specific antibodies for the diagnosis of lung cancer

Effects of a small molecule R-spondin-1 substitute RS-246204 on a mouse intestinal organoid culture

Differential tumor biological role of the tumor suppressor KAI1 and its splice variant in human breast cancer cells

Effects of interactions between common genetic variants and alcohol consumption on colorectal cancer risk

DAPK and CIP2A are involved in GAS6/AXL-mediated Schwann cell proliferation in a rat model of bilateral cavernous nerve injury

MYC-family protein overexpression and prominent nucleolar formation represent prognostic indicators and potential therapeutic targets for aggressive high-MKI neuroblastomas: a report from the children’s oncology group

TGF-β2-induced EMT is dampened by inhibition of autophagy and TNF-α treatment

Lysine-specific demethylase 1 inhibitors prevent teratoma development from human induced pluripotent stem cells

Intravesicular epidermal growth factor receptor subject to retrograde trafficking drives epidermal growth factor-dependent migration

SNP-array lesions in core binding factor acute myeloid leukemia

3D-Printed masks as a new approach for immobilization in radiotherapy – a study of positioning accuracy

Deciphering microRNA targets in pancreatic cancer using miRComb R package

Cysts mark the early stage of metastatic tumor development in non-small cell lung cancer

T cell infiltration into Ewing sarcomas is associated with local expression of immune-inhibitory HLA-G

Boolean analysis identifies CD38 as a biomarker of aggressive localized prostate cancer

mTOR inhibition enhances efficacy of dasatinib in ABL-rearranged Ph-like B-ALL

A meta-analysis on Omega-3 supplements in preventing recurrence of atrial fibrillation

A multicenter, retrospective analysis of elderly patients with acute myeloid leukemia who were treated with decitabine

The association between hydroxychloroquine treatment and cardiovascular morbidity among rheumatoid arthritis patients

Forty five percent of the Israeli population were infected with the influenza B Victoria virus during the winter season 2015–16

Pancreatic cancer: disease dynamics, tumor biology and the role of the microenvironment

Correction: Aliskiren therapy in hypertension and cardiovascular disease: a systematic review and a meta-analysis