Oncotarget

View Archive »

About The Cover

"Officially they announced a war against open access journals, but, in reality, they announced a war against publishers who do not retain subscription journals."

Table of Contents

Editorial

Librarians against scientists: Oncotarget's lesson

https://doi.org/10.18632/oncotarget.24272

Mikhail V. Blagosklonny
5515-5516
Abstract  |  PDF  |  Full Text  |  How to cite

Priority Research Papers

AntimiR17 therapy delays tumorigenesis in MYCdriven hepatocellular carcinoma HCC

https://doi.org/10.18632/oncotarget.22342

Renumathy Dhanasekaran, Meital Gabay-Ryan, Virginie Baylot, Ian Lai, Adriane Mosley, Xinqiang Huang, Sonya Zabludoff, Jian Li, Vivek Kaimal, Priya Karmali, and Dean W. Felsher
5517-5528
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Inhibition of the NEDD8 conjugation pathway induces calciumdependent compensatory activation of the prosurvival MEK/ERK pathway in acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.23797

Shuhua Zheng, Gilles M. Leclerc, Bin Li, Ronan T. Swords, and Julio C. Barredo
5529-5544
Abstract  |  PDF  |  Full Text  |  How to cite

Regulation of Ecadherin localization by microtubule targeting agents: rapid promotion of cortical Ecadherin through p130CAS/Src inhibition by eribulin

https://doi.org/10.18632/oncotarget.23798

Nicholas F. Dybdal-Hargreaves, April L. Risinger, and Susan L. Mooberry
5545-5561
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Gerotarget (Focus on Aging)

Ganglioside GM1 contributes to extracellular/intracellular regulation of insulin resistance impairment of insulin signaling and downstream eNOS activation in human aortic endothelial cells after short or longterm exposure to TNFα

https://doi.org/10.18632/oncotarget.23726

Norihiko Sasaki, Yoko Itakura, and Masashi Toyoda
5562-5577
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The involvement of serum exosomal miR5003p and miR7703p in aging: modulation by calorie restriction

https://doi.org/10.18632/oncotarget.23651

Eun Kyeong Lee, Hyoung Oh Jeong, Eun Jin Bang, Chul Hong Kim, Ji Young Mun, Seulgi Noh, Jeong-An Gim, Dae Hyun Kim, Ki Wung Chung, Byung Pal Yu, and Hae Young Chung
5578-5587
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MMP2A2M interaction increases ECM accumulation in aged rat kidney and its modulation by calorie restriction

https://doi.org/10.18632/oncotarget.23652

Kyung Mok Kim, Ki Wung Chung, Hyeong Oh Jeong, Bonggi Lee, Dae Hyun Kim, June Whoun Park, Seong Min Kim, Byung Pal Yu, and Hae Young Chung
5588-5599
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Association of serum levels of antibodies against MMP1 CBX1 and CBX5 with transient ischemic attack and cerebral infarction

https://doi.org/10.18632/oncotarget.23789

Hao Wang, Xiao-Meng Zhang, Go Tomiyoshi, Rika Nakamura, Natsuko Shinmen, Hideyuki Kuroda, Risa Kimura, Seiichiro Mine, Ikuo Kamitsukasa, Takeshi Wada, Akiyo Aotsuka, Yoichi Yoshida, Eiichi Kobayashi, Tomoo Matsutani, Yasuo Iwadate, Kazuo Sugimoto, Masahiro Mori, Akiyuki Uzawa, Mayumi Muto, Satoshi Kuwabara, Minoru Takemoto, Kazuki Kobayashi, Harukiyo Kawamura, Ryoichi Ishibashi, Koutaro Yokote, Mikiko Ohno, Po-Min Chen, Eiichiro Nishi, Koh Ono, Takeshi Kimura, Toshio Machida, Hirotaka Takizawa, Koichi Kashiwado, Hideaki Shimada, Masaaki Ito, Ken-Ichiro Goto, Katsuro Iwase, Hiromi Ashino, Akiko Taira, Emiko Arita, Masaki Takiguchi, and Takaki Hiwasa
5600-5613
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Anticoagulants inhibit proteolytic clearance of plasma amyloid beta

https://doi.org/10.18632/oncotarget.23718

Lu Yang, Arup Bhattacharya, Yun Li, and Yuesheng Zhang
5614-5626
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers: Immunology

Interferon sensitivitydetermining region of hepatitis C virus influences virus production and interferon signaling

https://doi.org/10.18632/oncotarget.23562

Ryuichi Sugiyama, Asako Murayama, Sayuri Nitta, Norie Yamada, Megumi Tasaka-Fujita, Takahiro Masaki, Hussein Hassan Aly, Masaaki Shiina, Akihide Ryo, Koji Ishii, Takaji Wakita, and Takanobu Kato
5627-5640
Abstract  |  PDF  |  Full Text  |  How to cite

NAB2 is a novel immune stimulator of MDA5 that promotes a strong type I interferon response

https://doi.org/10.18632/oncotarget.23725

Anne Oberson, Lorenzo Spagnuolo, Viola Puddinu, Winfried Barchet, Karola Rittner, and Carole Bourquin
5641-5651
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Microsatellite instability is a biomarker for immune checkpoint inhibitors in endometrial cancer

https://doi.org/10.18632/oncotarget.23790

Hitomi Yamashita, Kentaro Nakayama, Masako Ishikawa, Kohei Nakamura, Tomoka Ishibashi, Kaori Sanuki, Ruriko Ono, Hiroki Sasamori, Toshiko Minamoto, Kouji Iida, Razia Sultana, Noriyoshi Ishikawa, and Satoru Kyo
5652-5664
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers

Converging blockchain and nextgeneration artificial intelligence technologies to decentralize and accelerate biomedical research and healthcare

https://doi.org/10.18632/oncotarget.22345

Polina Mamoshina, Lucy Ojomoko, Yury Yanovich, Alex Ostrovski, Alex Botezatu, Pavel Prikhodko, Eugene Izumchenko, Alexander Aliper, Konstantin Romantsov, Alexander Zhebrak, Iraneus Obioma Ogu, and Alex Zhavoronkov
5665-5690
Abstract  |  PDF  |  Full Text  |  How to cite

Combining molecular and immunohistochemical analyses of key drivers in primary melanomas: interplay between germline and somatic variations

https://doi.org/10.18632/oncotarget.23204

William Bruno, Claudia Martinuzzi, Bruna Dalmasso, Virginia Andreotti, Lorenza Pastorino, Francesco Cabiddu, Marina Gualco, Francesco Spagnolo, Alberto Ballestrero, Paola Queirolo, Federica Grillo, Luca Mastracci, and Paola Ghiorzo
5691-5702
Abstract  |  PDF  |  Full Text  |  How to cite

Consecutive epigeneticallyactive agent combinations act in ID1RUNX3TET2 and HOXA pathways for Flt3ITD+ve AML

https://doi.org/10.18632/oncotarget.23655

Hamid Sayar, Yan Liu, Rui Gao, Mohammad Abu Zaid, Larry D. Cripe, Jill Weisenbach, Katie J. Sargent, Mehdi Nassiri, Lang Li, Heiko Konig, Attaya Suvannasankha, Feng Pan, Rajasubramaniam Shanmugam, Chirayu Goswami, Reuben Kapur, Mingjiang Xu, and H. Scott Boswell
5703-5715
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The protein kinase SIK downregulates the polarity protein Par3

https://doi.org/10.18632/oncotarget.23788

Michael Vanlandewijck, Mahsa Shahidi Dadras, Marta Lomnytska, Tanzila Mahzabin, Martin Lee Miller, Christer Busch, Søren Brunak, Carl-Henrik Heldin, and Aristidis Moustakas
5716-5735
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Underexpression of CK2β subunit in ccRCC represents a complementary biomarker of pSTAT3 Ser727 that correlates with patient survival

https://doi.org/10.18632/oncotarget.23422

Jordi Vilardell, Estefania Alcaraz, Eduard Sarró, Enric Trilla, Thaïs Cuadros, Inés de Torres, Maria Plana, Santiago Ramón y Cajal, Lorenzo A. Pinna, Maria Ruzzene, Juan Morote, Anna Meseguer, and Emilio Itarte
5736-5751
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Phospholipase Cγ1 links inflammation and tumorigenesis in colitisassociated cancer

https://doi.org/10.18632/oncotarget.23430

Kwang-Il Park, Kwang-Youn Kim, Tae Woo Oh, Du-Seock Kang, Eung-Kyun Kim, Yong Ryoul Yang, Young-Kyo Seo, Jin-Yeul Ma, and Pann-Ghill Suh
5752-5763
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Stromaderived extracellular vesicles deliver tumorsuppressive miRNAs to pancreatic cancer cells

https://doi.org/10.18632/oncotarget.23532

Song Han, David H. Gonzalo, Michael Feely, Carlos Rinaldi, Sayali Belsare, Haiyan Zhai, Krishan Kalra, Michael H. Gerber, Christopher E. Forsmark, and Steven J. Hughes
5764-5777
Abstract  |  PDF  |  Full Text  |  How to cite

Longterm prediction of prostate cancer diagnosis and death using PSA and obesity related anthropometrics at early middle age: data from the malmö preventive project

https://doi.org/10.18632/oncotarget.22981

Melissa J. Assel, Axel Gerdtsson, Daniel L.J. Thorek, Sigrid V. Carlsson, Johan Malm, Peter T. Scardino, Andrew Vickers, Hans Lilja, and David Ulmert
5778-5785
Abstract  |  PDF  |  Full Text  |  How to cite

Analysis of the circular RNA transcriptome in endometrial cancer

https://doi.org/10.18632/oncotarget.23534

Bei Jun Chen, Frances L. Byrne, Konii Takenaka, Susan C. Modesitt, Ellen M. Olzomer, James D. Mills, Rhonda Farrell, Kyle L. Hoehn, and Michael Janitz
5786-5796
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Upregulation of cell cycle genes in head and neck cancer patients may be antagonized by erufosine's down regulation of cell cycle processes in OSCC cells

https://doi.org/10.18632/oncotarget.23537

Shariq S. Ansari, Ashwini K. Sharma, Michael Zepp, Elizabet Ivanova, Frank Bergmann, Rainer König, and Martin R. Berger
5797-5810
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Breast cancer stem cells in HER2negative breast cancer cells contribute to HER2mediated radioresistance and molecular subtype conversion: clinical implications for serum HER2 in recurrent HER2negative breast cancer

https://doi.org/10.18632/oncotarget.23528

Yun Gyoung Kim, Yi Na Yoon, Hyang Suk Choi, Ji-Hyun Kim, Hyesil Seol, Jin Kyung Lee, Min-Ki Seong, In Chul Park, Kwang Il Kim, Hyun-Ah Kim, Jae-Sung Kim, and Woo Chul Noh
5811-5822
Abstract  |  PDF  |  Full Text  |  How to cite

Comparison of the modified lowdose cytarabine and etoposide with decitabine therapy for elderly acute myeloid leukemia patients unfit for intensive chemotherapy

https://doi.org/10.18632/oncotarget.23629

Seung-Hwan Shin, Byung-Sik Cho, Sung-Soo Park, Sung-Yeon Cho, Young-Woo Jeon, Jae-Ho Yoon, Seung-Ah Yahng, Sung-Eun Lee, Dong-Gun Lee, Ki-Seong Eom, Yoo-Jin Kim, Seok Lee, Chang-Ki Min, Seok-Goo Cho, Dong-Wook Kim, Jong-Wook Lee, Woo-Sung Min, and Hee-Je Kim
5823-5833
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The influence of chemotherapy on adenosineproducing B cells in patients with head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.23533

Andreas Ziebart, Ulrich Huber, Sandra Jeske, Simon Laban, Johannes Doescher, Thomas K. Hoffmann, Cornelia Brunner, Edwin K. Jackson, and Patrick J. Schuler
5834-5847
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

High RAC3 expression levels are required for induction and maintaining of cancer cell stemness

https://doi.org/10.18632/oncotarget.23635

Laura C. Panelo, Mileni Soares Machado, María F. Rubio, Felipe Jaworski, Cecilia V. Alvarado, Leonardo A. Paz, Alejandro J. Urtreger, Elba Vazquez, and Mónica A. Costas
5848-5860
Abstract  |  PDF  |  Full Text  |  How to cite

Activation of Grm1 expression by mutated BRaf V600E in vitro and in vivo

https://doi.org/10.18632/oncotarget.23637

Ho-Chung Chen, Jairo Sierra, Lumeng Jenny Yu, Robert Cerchio Jr., Brian A. Wall, James Goydos, and Suzie Chen
5861-5875
Abstract  |  PDF  |  Full Text  |  How to cite

Inhibition of NFκB prevents the acidic bileinduced oncogenic mRNA phenotype in human hypopharyngeal cells

https://doi.org/10.18632/oncotarget.23143

Dimitra P. Vageli, Sotirios G. Doukas, and Clarence T. Sasaki
5876-5891
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

YAPassociated chromosomal instability and cholangiocarcinoma in mice

https://doi.org/10.18632/oncotarget.23638

Sumera I Ilyas, Samantha R. Fischbach, Steven F. Bronk, Petra Hirsova, Anuradha Krishnan, Renumathy Dhanasekaran, James B. Smadbeck, Rory L. Smoot, George Vasmatzis, and Gregory J. Gores
5892-5905
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Zinc finger protein 598 inhibits cell survival by promoting UVinduced apoptosis

https://doi.org/10.18632/oncotarget.23643

Qiaohong Yang, and Romi Gupta
5906-5918
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The transcriptional and mutational landscapes of lipid metabolismrelated genes in colon cancer

https://doi.org/10.18632/oncotarget.23592

Lara P. Fernández, Ricardo Ramos-Ruiz, Jesús Herranz, Roberto Martín-Hernández, Teodoro Vargas, Marta Mendiola, Laura Guerra, Guillermo Reglero, Jaime Feliu, and Ana Ramírez de Molina
5919-5930
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Pathological and functional significance of Semaphorin5A in pancreatic cancer progression and metastasis

https://doi.org/10.18632/oncotarget.23644

Sugandha Saxena, Yuri Hayashi, Lingyun Wu, Mohammad Awaji, Pranita Atri, Michelle L. Varney, Abhilasha Purohit, Satyanarayana Rachagani, Surinder K. Batra, and Rakesh K. Singh
5931-5943
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification and characterization of novel enhanced cell penetrating peptides for anticancer cargo delivery

https://doi.org/10.18632/oncotarget.23179

Xiguang Zhang, Jean Yves Brossas, Christophe Parizot, Jean Marc Zini, and Angelita Rebollo
5944-5957
Abstract  |  PDF  |  Full Text  |  How to cite

A dock derived compound against laminin receptor 37 LR exhibits anticancer properties in a prostate cancer cell line model

https://doi.org/10.18632/oncotarget.23236

Charles Samuel Umbaugh, Adriana Diaz-Quiñones, Manoel Figueiredo Neto, Joseph J. Shearer, and Marxa L. Figueiredo
5958-5978
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Src is the primary target of aripiprazole an atypical antipsychotic drug in its antitumor action

https://doi.org/10.18632/oncotarget.23192

Mi Seon Kim, Byong Chul Yoo, Woo Seok Yang, Sang Yun Han, Deok Jeong, Jun Min Song, Kyung Hee Kim, Adithan Aravinthan, Ji Hye Kim, Jong-Hoon Kim, Seung Cheol Kim, and Jae Youl Cho
5979-5992
Abstract  |  PDF  |  Full Text  |  How to cite

Inhibition of IAP’s and activation of p53 leads to caspasedependent apoptosis in gastric cancer cells treated with Scutellarein

https://doi.org/10.18632/oncotarget.23202

Venu Venkatarame Gowda Saralamma, Ho Jeong Lee, Suchismita Raha, Won Sup Lee, Eun Hee Kim, Sang Joon Lee, Jeong Doo Heo, Chungkil Won, Chang Keun Kang, and Gon Sup Kim
5993-6006
Abstract  |  PDF  |  Full Text  |  How to cite

Assessing tumor molecular profiling to guide treatments for patients with advanced female genital tract malignancy

https://doi.org/10.18632/oncotarget.23675

Philip Carter, Costi Alifrangis, Biancastella Cereser, Pramodh Chandrasinghe, Lisa Del Bel Belluz, Christina Fotopoulou, Andreja Frilling, Thomas Herzog, Nina Moderau, Neha Tabassum, Jonathan Krell, and Justin Stebbing
6007-6014
Abstract  |  PDF  |  Full Text  |  How to cite

Human papillomavirus E7 oncoprotein expression by keratinocytes alters the cytotoxic mechanisms used by CD8 T cells

https://doi.org/10.18632/oncotarget.23210

Purnima Bhat, Anne-Sophie Bergot, Nigel Waterhouse, and Ian Hector Frazer
6015-6027
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Epigenetic changes found in uterine decidual and placental tissues can also be found in the breast cancer microenvironment of the same unique patient: description and potential interpretations

https://doi.org/10.18632/oncotarget.23488

Miguel H. Bronchud, Francesc Tresserra, and Bernat Serra Zantop
6028-6041
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Combination of a thioxodihydroquinazolinone with cisplatin eliminates ovarian cancer stem celllike cells CSCLCs and shows preclinical potential

https://doi.org/10.18632/oncotarget.23679

Jing Ma, Joseph Salamoun, Peter Wipf, Robert Edwards, Bennett Van Houten, and Wei Qian
6042-6054
Abstract  |  PDF  |  Full Text  |  How to cite

Rapid development of myeloproliferative neoplasm in mice with Ptpn11D61Y mutation and haploinsufficient for Dnmt3a

https://doi.org/10.18632/oncotarget.23680

Lisa Deng, Briana M. Richine, Elizabeth L. Virts, Victoria N. Jideonwo-Auman, Rebecca J. Chan, and Reuben Kapur
6055-6061
Abstract  |  PDF  |  Full Text  |  How to cite

[Neratinib + Valproate] exposure permanently reduces ERBB1 and RAS expression in 4T1 mammary tumors and enhances M1 macrophage infiltration

https://doi.org/10.18632/oncotarget.23681

Laurence Booth, Jane L. Roberts, Rumeesa Rais, John Kirkwood, Francesca Avogadri-Connors, Richard E. Cutler Jr., Alshad S. Lalani, Andrew Poklepovic, and Paul Dent
6062-6074
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Expression of Wntsignaling pathway genes and their associations with miRNAs in colorectal cancer

https://doi.org/10.18632/oncotarget.23636

Martha L. Slattery, Lila E. Mullany, Lori C. Sakoda, Wade S. Samowitz, Roger K. Wolff, John R. Stevens, and Jennifer S. Herrick
6075-6085
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Construction of key signal regulatory network in metastatic colorectal cancer

https://doi.org/10.18632/oncotarget.23710

Lu Qi, and Yanqing Ding
6086-6094
Abstract  |  PDF  |  Full Text  |  How to cite

Type IIB DNA topoisomerase is downregulated by trastuzumab and doxorubicin to synergize cardiotoxicity

https://doi.org/10.18632/oncotarget.23543

Jiangsong Jiang, Nishant Mohan, Yukinori Endo, Yi Shen, and Wen Jin Wu
6095-6108
Abstract  |  PDF  |  Full Text  |  How to cite

Characterization and metabolic synthetic lethal testing in a new model of SDHloss familial pheochromocytoma and paraganglioma

https://doi.org/10.18632/oncotarget.23639

John Smestad, Oksana Hamidi, Lin Wang, Molly Nelson Holte, Fatimah Al Khazal, Luke Erber, Yue Chen, and L. James Maher III
6109-6127
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Drp1/Fis1 interaction mediates mitochondrial dysfunction bioenergetic failure and cognitive decline in Alzheimer's disease

https://doi.org/10.18632/oncotarget.23640

Amit U. Joshi, Nay L. Saw, Mehrdad Shamloo, and Daria Mochly-Rosen
6128-6143
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Natural and molecular history of prolactinoma: insights from a Prlr–/– mouse model

https://doi.org/10.18632/oncotarget.23713

Valérie Bernard, Chiara Villa, Aurélie Auguste, Sophie Lamothe, Anne Guillou, Agnès Martin, Sandrine Caburet, Jacques Young, Reiner A. Veitia, and Nadine Binart
6144-6155
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Cellcell fusion as a mechanism of DNA exchange in cancer

https://doi.org/10.18632/oncotarget.23715

Stephen C. Searles, Endi K. Santosa, and Jack D. Bui
6156-6173
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Combined inhibition of CDK and HDAC as a promising therapeutic strategy for both cutaneous and uveal metastatic melanoma

https://doi.org/10.18632/oncotarget.23485

Renier Heijkants, Karen Willekens, Mark Schoonderwoerd, Amina Teunisse, Maaike Nieveen, Enrico Radaelli, Luuk Hawinkels, Jean-Christophe Marine, and Aart Jochemsen
6174-6187
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Translational study reveals a twofaced role of RBM3 in pancreatic cancer and suggests its potential value as a biomarker for improved patient stratification

https://doi.org/10.18632/oncotarget.23486

Emelie Karnevi, Liv Ben Dror, Adil Mardinoglu, Jacob Elebro, Margareta Heby, Sven-Erik Olofsson, Björn Nodin, Jakob Eberhard, William Gallagher, Mathias Uhlén, and Karin Jirström
6188-6200
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The presence of PD1 positive tumor infiltrating lymphocytes in triple negative breast cancers is associated with a favorable outcome of disease

https://doi.org/10.18632/oncotarget.23717

Gero Brockhoff, Stephan Seitz, Florian Weber, Florian Zeman, Monika Klinkhammer-Schalke, Olaf Ortmann, and Anja Kathrin Wege
6201-6212
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Near infrared fluorescence imaging of EGFR expression in vivo using IRDye800CWnimotuzumab

https://doi.org/10.18632/oncotarget.23557

Wendy Bernhard, Ayman El-Sayed, Kris Barreto, Carolina Gonzalez, Wayne Hill, Angel Casaco Parada, Humphrey Fonge, and C. Ronald Geyer
6213-6227
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Gene aberration profile of tumors of adolescent and young adult females

https://doi.org/10.18632/oncotarget.23765

Yasuyuki Kanke, Akihiko Shimomura, Motonobu Saito, Takayuki Honda, Kouya Shiraishi, Yoko Shimada, Reiko Watanabe, Hiroshi Yoshida, Masayuki Yoshida, Chikako Shimizu, Kazuaki Takahashi, Hirohiko Totsuka, Hideaki Ogiwara, Sou Hirose, Koji Kono, Kenji Tamura, Aikou Okamoto, Takayuki Kinoshita, Tomoyasu Kato, and Takashi Kohno
6228-6237
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prognostic significance of heparanase expression in primary and metastatic breast carcinoma

https://doi.org/10.18632/oncotarget.23560

Olga Vornicova, Inna Naroditsky, Ilanit Boyango, Shlomit S. Shachar, Tanya Mashiach, Neta Ilan, Israel Vlodavsky, and Gil Bar-Sela
6238-6244
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Determination of candidate metabolite biomarkers associated with recurrence of HCVrelated hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.23500

Zhicheng Liu, Pierre Nahon, Zaifang Li, Peiyuan Yin, Yanli Li, Roland Amathieu, Nathalie Ganne-Carrié, Marianne Ziol, Nicolas Sellier, Olivier Seror, Laurence Le Moyec, Philippe Savarin, and Guowang Xu
6245-6258
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

2Amino3methylcarboxy5heptylthiophene TJ191 is a selective anticancer small molecule that targets low TβRIIIexpressing malignant Tcell leukemia/lymphoma cells

https://doi.org/10.18632/oncotarget.23501

Ahmed El-Gazzar, Sam Noppen, Joice Thomas, Wim Dehaen, Jan Balzarini, and Sandra Liekens
6259-6269
Abstract  |  PDF  |  Full Text  |  How to cite

Activation of p53 and destabilization of androgen receptor by combinatorial inhibition of MDM2 and MDMX in prostate cancer cells

https://doi.org/10.18632/oncotarget.23569

Harman Chopra, Zara Khan, Jamie Contreras, Herui Wang, Abanob Sedrak, and Yan Zhu
6270-6281
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

LIMD1 is induced by and required for LMP1 signaling and protects EBVtransformed cells from DNA damageinduced cell death

https://doi.org/10.18632/oncotarget.23676

Ling Wang, Mary E.A. Howell, Brooke McPeak, Katrina Riggs, Carissa Kohne, Jether Uel Yohanon, Daniel E. Foxler, Tyson V. Sharp, Jonathan P. Moorman, Zhi Q. Yao, and Shunbin Ning
6282-6297
Abstract  |  PDF  |  Full Text  |  How to cite

The possible existence of occult metastasis in patients with ovarian clearcell carcinoma who underwent complete resection without any residual tumours

https://doi.org/10.18632/oncotarget.23921

Hiroaki Kajiyama, Shiro Suzuki, Masato Yoshihara, Kimihiro Nishino, Nobuhisa Yoshikawa, Fumi Utsumi, Kaoru Niimi, Mika Mizuno, Michiyasu Kawai, Hidenori Oguchi, Kimio Mizuno, Osamu Yamamuro, Tetsuro Nagasaka, Kiyosumi Shibata, and Fumitaka Kikkawa
6298-6307
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A lethal synergy induced by phellinus linteus and camptothecin11 in colon cancer cells

https://doi.org/10.18632/oncotarget.23918

Tianqi Yu, Suthakar Ganapathy, Ling Shen, Bo Peng, Sung-Hoon Kim, Alexandros Makriyannis, and Changyan Chen
6308-6319
Abstract  |  PDF  |  Full Text  |  How to cite

Interleukin 8 activity influences the efficacy of adenoviral oncolytic immunotherapy in cancer patients

https://doi.org/10.18632/oncotarget.23967

Kristian Taipale, Siri Tähtinen Tähtinen, Riikka Havunen, Anniina Koski, Ilkka Liikanen, Päivi Pakarinen Pakarinen, Riitta Koivisto-Korander, Matti Kankainen, Timo Joensuu, Anna Kanerva, and Akseli Hemminki
6320-6335
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Quantitative radiomic profiling of glioblastoma represents transcriptomic expression

https://doi.org/10.18632/oncotarget.23975

Doo-Sik Kong, Junhyung Kim, Gyuha Ryu, Hye-Jin You, Joon Kyung Sung, Yong Hee Han, Hye-Mi Shin, In-Hee Lee, Sung-Tae Kim, Chul-Kee Park, Seung Hong Choi, Jeong Won Choi, Ho Jun Seol, Jung-Il Lee, and Do-Hyun Nam
6336-6345
Abstract  |  PDF  |  Full Text  |  How to cite

Complement C4dspecific antibodies for the diagnosis of lung cancer

https://doi.org/10.18632/oncotarget.23690

Daniel Ajona, Marcin Okrój, María J. Pajares, Jackeline Agorreta, María D. Lozano, Javier J. Zulueta, Carla Verri, Luca Roz, Gabriella Sozzi, Ugo Pastorino, Pierre P. Massion, Luis M. Montuenga, Anna M. Blom, and Ruben Pio
6346-6355
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Effects of a small molecule Rspondin1 substitute RS246204 on a mouse intestinal organoid culture

https://doi.org/10.18632/oncotarget.23721

Myeong-Ok Nam, Soojung Hahn, Joo Hyun Jee, Tae-Sun Hwang, Ho Yoon, Dong Hyeon Lee, Min-Soo Kwon, and Jongman Yoo
6356-6368
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Differential tumor biological role of the tumor suppressor KAI1 and its splice variant in human breast cancer cells

https://doi.org/10.18632/oncotarget.23968

Julia Miller, Tobias F. Dreyer, Anne Benge, Eva-Kathrin Sinner, Christine Heinrich, Anke Benge, Eva Gross, Sarah Preis, Jan Rother, Anthony Roberts, Gabriele Nelles, Tzenka Miteva, and Ute Reuning
6369-6390
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Effects of interactions between common genetic variants and alcohol consumption on colorectal cancer risk

https://doi.org/10.18632/oncotarget.23997

Nan Song, Aesun Shin, Jae Hwan Oh, and Jeongseon Kim
6391-6401
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

DAPK and CIP2A are involved in GAS6/AXLmediated Schwann cell proliferation in a rat model of bilateral cavernous nerve injury

https://doi.org/10.18632/oncotarget.23978

Yen-Lin Chen, Yi-Ting Tsai, Ting-Ting Chao, Yi-No Wu, Meng-Chuan Chen, Ying-Hung Lin, Chun-Hou Liao, Shang-Shing P. Chou, and Han-Sun Chiang
6402-6415
Abstract  |  PDF  |  Full Text  |  How to cite

MYCfamily protein overexpression and prominent nucleolar formation represent prognostic indicators and potential therapeutic targets for aggressive highMKI neuroblastomas: a report from the children’s oncology group

https://doi.org/10.18632/oncotarget.23740

Risa Niemas-Teshiba, Ryosuke Matsuno, Larry L. Wang, Xao X. Tang, Bill Chiu, Jasmine Zeki, Jeannine Coburn, Kimberly Ornell, Arlene Naranjo, Collin Van Ryn, Wendy B. London, Michael D. Hogarty, Julie M. Gastier-Foster, A. Thomas Look, Julie R. Park, John M. Maris, Susan L. Cohn, Robert C. Seeger, Shahab Asgharzadeh, Naohiko Ikegak, and Hiroyuki Shimada
6416-6432
Abstract  |  PDF  |  Full Text  |  How to cite

TGFβ2induced EMT is dampened by inhibition of autophagy and TNFα treatment

https://doi.org/10.18632/oncotarget.23942

Subhra Dash, Prasad M. Sarashetti, Balaji Rajashekar, Rajdeep Chowdhury, and Sudeshna Mukherjee
6433-6449
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Lysinespecific demethylase 1 inhibitors prevent teratoma development from human induced pluripotent stem cells

https://doi.org/10.18632/oncotarget.24030

Naoki Osada, Jiro Kikuchi, Takashi Umehara, Shin Sato, Masashi Urabe, Tomoyuki Abe, Nakanobu Hayashi, Masahiko Sugitani, Yutaka Hanazono, and Yusuke Furukawa
6450-6462
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Intravesicular epidermal growth factor receptor subject to retrograde trafficking drives epidermal growth factordependent migration

https://doi.org/10.18632/oncotarget.23766

Sabrina Maisel, Derrick Broka, and Joyce Schroeder
6463-6477
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

SNParray lesions in core binding factor acute myeloid leukemia

https://doi.org/10.18632/oncotarget.24031

Nicolas Duployez, Elise Boudry-Labis, Christophe Roumier, Nicolas Boissel, Arnaud Petit, Sandrine Geffroy, Nathalie Helevaut, Karine Celli-Lebras, Christine Terre, Odile Fenneteau, Wendy Cuccuini, Isabelle Luquet, Helene Lapillonne, Catherine Lacombe, Pascale Cornillet, Norbert Ifrah, Herve Dombret, Guy Leverger, Eric Jourdan, and Claude Preudhomme
6478-6489
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

3DPrinted masks as a new approach for immobilization in radiotherapy – a study of positioning accuracy

https://doi.org/10.18632/oncotarget.24032

Matthias Felix Haefner, Frederik Lars Giesel, Matthias Mattke, Daniel Rath, Moritz Wade, Jacob Kuypers, Alan Preuss, Hans-Ulrich Kauczor, Jens-Peter Schenk, Juergen Debus, Florian Sterzing, and Roland Unterhinninghofen
6490-6498
Abstract  |  PDF  |  Full Text  |  How to cite

Deciphering microRNA targets in pancreatic cancer using miRComb R package

https://doi.org/10.18632/oncotarget.24034

Maria Vila-Casadesus, Elena Vila-Navarro, Giulia Raimondi, Cristina Fillat, Antoni Castells, Juan Jose Lozano, and Meritxell Gironella
6499-6517
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Cysts mark the early stage of metastatic tumor development in nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.23785

Chitra Thakur, Ulf R. Rapp, and Thomas Rudel
6518-6535
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

T cell infiltration into Ewing sarcomas is associated with local expression of immuneinhibitory HLAG

https://doi.org/10.18632/oncotarget.23815

Christian Spurny, Sareetha Kailayangir, Bianca Altvater, Silke Jamitzky, Wolfgang Hartmann, Eva Wardelmann, Andreas Ranft, Uta Dirksen, Susanne Amler, Jendrik Hardes, Maike Fluegge, Jutta Meltzer, Nicole Farwick, Lea Greune, and Claudia Rossig
6536-6549
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Boolean analysis identifies CD38 as a biomarker of aggressive localized prostate cancer

https://doi.org/10.18632/oncotarget.23973

Debashis Sahoo, Wei Wei, Heidi Auman, Antonio Hurtado-Coll, Peter R. Carroll, Ladan Fazli, Martin E. Gleave, Daniel W. Lin, Peter S. Nelson, Jeff Simko, Ian M. Thompson, Robin J. Leach, Dean A. Troyer, Lawrence D. True, Jesse K. McKenney, Ziding Feng, and James D. Brooks
6550-6561
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

mTOR inhibition enhances efficacy of dasatinib in ABLrearranged Phlike BALL

https://doi.org/10.18632/oncotarget.24020

Moran Gotesman, Thanh-Trang T. Vo, Lee-Or Herzog, Tiffeny Tea, Sharmila Mallya, Sarah K. Tasian, Marina Konopleva, and David A. Fruman
6562-6571
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Meta-Analysis

Impact of LMP7 rs2071543 gene polymorphism in increasing cancer risk: evidence from a metaanalysis and trial sequential analysis

https://doi.org/10.18632/oncotarget.23547

Raju K. Mandal, Sajad A. Dar, Arshad Jawed, Mohd Wahid, Mohtashim Lohani, Aditya K. Panda, Bhartendu N. Mishra, Naseem Akhter, Mohammed Y. Areeshi, and Shafiul Haque
6572-6585
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A metaanalysis on Omega3 supplements in preventing recurrence of atrial fibrillation

https://doi.org/10.18632/oncotarget.23783

Ying Jiang, Hui Ching Tan, Wilson Wai San Tam, Toon Wei Lim, and Wenru Wang
6586-6594
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinical Research Papers

An integrated analysis of hyponatremia in cancer patients receiving platinumbased or nonplatinumbased chemotherapy in clinical trials JCOG1405A

https://doi.org/10.18632/oncotarget.23536

Yasumasa Ezoe, Junki Mizusawa, Hiroshi Katayama, Kozo Kataoka, and Manabu Muto
6595-6606
Abstract  |  PDF  |  Full Text  |  How to cite

A multicenter retrospective analysis of elderly patients with acute myeloid leukemia who were treated with decitabine

https://doi.org/10.18632/oncotarget.23823

Jun Ho Yi, Silvia Park, Jung Han Kim, Young-Woong Won, Do Hyoung Lim, Boram Han, Jieun Uhm, Hae Su Kim, Chul Won Jung, and Jun Ho Jang
6607-6614
Abstract  |  PDF  |  Full Text  |  How to cite

The association between hydroxychloroquine treatment and cardiovascular morbidity among rheumatoid arthritis patients

https://doi.org/10.18632/oncotarget.23570

Michael Shapiro, and Yair Levy
6615-6622
Abstract  |  PDF  |  Full Text  |  How to cite

Forty five percent of the Israeli population were infected with the influenza B Victoria virus during the winter season 2015–16

https://doi.org/10.18632/oncotarget.23601

Sivan Sharabi, Ravit Bassal, Nehemya Friedman, Yaron Drori, Hadar Alter, Aharona Glatman-Freedman, Musa Hindiyeh, Danny Cohen, Ella Mendelson, Tamar Shohat, and Michal Mandelboim
6623-6629
Abstract  |  PDF  |  Full Text  |  How to cite

Reviews

Implications of KRAS mutations in acquired resistance to treatment in NSCLC

https://doi.org/10.18632/oncotarget.23553

Marzia Del Re, Eleonora Rofi, Giuliana Restante, Stefania Crucitta, Elena Arrigoni, Stefano Fogli, Massimo Di Maio, Iacopo Petrini, and Romano Danesi
6630-6643
Abstract  |  PDF  |  Full Text  |  How to cite

Pancreatic cancer: disease dynamics tumor biology and the role of the microenvironment

https://doi.org/10.18632/oncotarget.24019

Daniel Ansari, Helmut Friess, Monika Bauden, Johan Samnegård, and Roland Andersson
6644-6651
Abstract  |  PDF  |  Full Text  |  How to cite

Case Reports

Pneumatocele during sorafenib therapy: first report of an unusual complication

https://doi.org/10.18632/oncotarget.23599

Paloma Sangro, Idoia Bilbao, Nerea Fernández-Ros, Mercedes Iñarrairaegui, Javier Zulueta, JI Bilbao, and Bruno Sangro
6652-6656
Abstract  |  PDF  |  Full Text  |  How to cite

Corrections

Correction: The optimal time of initiation of renal replacement therapy in acute kidney injury: A metaanalysis

https://doi.org/10.18632/oncotarget.24254

Kaiping Luo, Shufang Fu, Weidong Fang, and Gaosi Xu
6657-6657
Correction  |  PDF  |  How to cite

Correction: Aliskiren therapy in hypertension and cardiovascular disease: a systematic review and a metaanalysis

https://doi.org/10.18632/oncotarget.24255

Shufang Fu, Xin Wen, Fei Han, Yin Long, and Gaosi Xu
6658-6658
Correction  |  PDF  |  How to cite


Copyright © 2026 Rapamycin Press LLC dba Impact Journals
Oncotarget ® is a registered trademark of Rapamycin Press LLC
Impact Journals ® is a registered trademark of Rapamycin Press LLC
RAPAMYCIN PRESS ® is a registered trademark of Rapamycin Press LLC
By using our site you are giving us permission to use cookies. This website collects cookies to deliver a better user experience, and to analyze our website traffic and performance. Personal data is not collected.