VOLUME 9 (2018)
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About The Cover
"Officially they announced a war against open access journals, but, in reality, they announced a war against publishers who do not retain subscription journals."
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Table of Contents
Editorial
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| Librarians against scientists: Oncotarget's lesson |
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https://doi.org/10.18632/oncotarget.24272
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| 5515-5516 |
Priority Research Papers
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| AntimiR17 therapy delays tumorigenesis in MYCdriven hepatocellular carcinoma HCC |
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https://doi.org/10.18632/oncotarget.22342
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| 5517-5528 |
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| Inhibition of the NEDD8 conjugation pathway induces calciumdependent compensatory activation of the prosurvival MEK/ERK pathway in acute lymphoblastic leukemia |
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https://doi.org/10.18632/oncotarget.23797
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| 5529-5544 |
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| Regulation of Ecadherin localization by microtubule targeting agents: rapid promotion of cortical Ecadherin through p130CAS/Src inhibition by eribulin |
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https://doi.org/10.18632/oncotarget.23798
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| 5545-5561 |
Research Papers: Gerotarget (Focus on Aging)
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| Ganglioside GM1 contributes to extracellular/intracellular regulation of insulin resistance impairment of insulin signaling and downstream eNOS activation in human aortic endothelial cells after short or longterm exposure to TNFα |
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https://doi.org/10.18632/oncotarget.23726
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| 5562-5577 |
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| The involvement of serum exosomal miR5003p and miR7703p in aging: modulation by calorie restriction |
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https://doi.org/10.18632/oncotarget.23651
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| 5578-5587 |
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| MMP2A2M interaction increases ECM accumulation in aged rat kidney and its modulation by calorie restriction |
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https://doi.org/10.18632/oncotarget.23652
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| 5588-5599 |
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| Association of serum levels of antibodies against MMP1 CBX1 and CBX5 with transient ischemic attack and cerebral infarction |
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https://doi.org/10.18632/oncotarget.23789
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| 5600-5613 |
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| Anticoagulants inhibit proteolytic clearance of plasma amyloid beta |
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https://doi.org/10.18632/oncotarget.23718
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| 5614-5626 |
Research Papers: Immunology
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| Interferon sensitivitydetermining region of hepatitis C virus influences virus production and interferon signaling |
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https://doi.org/10.18632/oncotarget.23562
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| 5627-5640 |
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| NAB2 is a novel immune stimulator of MDA5 that promotes a strong type I interferon response |
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https://doi.org/10.18632/oncotarget.23725
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| 5641-5651 |
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| Microsatellite instability is a biomarker for immune checkpoint inhibitors in endometrial cancer |
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https://doi.org/10.18632/oncotarget.23790
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| 5652-5664 |
Research Papers
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| Converging blockchain and nextgeneration artificial intelligence technologies to decentralize and accelerate biomedical research and healthcare |
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https://doi.org/10.18632/oncotarget.22345
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| 5665-5690 |
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| Combining molecular and immunohistochemical analyses of key drivers in primary melanomas: interplay between germline and somatic variations |
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https://doi.org/10.18632/oncotarget.23204
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| 5691-5702 |
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| Consecutive epigeneticallyactive agent combinations act in ID1RUNX3TET2 and HOXA pathways for Flt3ITD+ve AML |
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https://doi.org/10.18632/oncotarget.23655
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| 5703-5715 |
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| The protein kinase SIK downregulates the polarity protein Par3 |
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https://doi.org/10.18632/oncotarget.23788
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| 5716-5735 |
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| Underexpression of CK2β subunit in ccRCC represents a complementary biomarker of pSTAT3 Ser727 that correlates with patient survival |
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https://doi.org/10.18632/oncotarget.23422
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| 5736-5751 |
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| Phospholipase Cγ1 links inflammation and tumorigenesis in colitisassociated cancer |
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https://doi.org/10.18632/oncotarget.23430
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| 5752-5763 |
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| Stromaderived extracellular vesicles deliver tumorsuppressive miRNAs to pancreatic cancer cells |
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https://doi.org/10.18632/oncotarget.23532
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| 5764-5777 |
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| Longterm prediction of prostate cancer diagnosis and death using PSA and obesity related anthropometrics at early middle age: data from the malmö preventive project |
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https://doi.org/10.18632/oncotarget.22981
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| 5778-5785 |
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| Analysis of the circular RNA transcriptome in endometrial cancer |
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https://doi.org/10.18632/oncotarget.23534
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| 5786-5796 |
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| Upregulation of cell cycle genes in head and neck cancer patients may be antagonized by erufosine's down regulation of cell cycle processes in OSCC cells |
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https://doi.org/10.18632/oncotarget.23537
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| 5797-5810 |
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| Breast cancer stem cells in HER2negative breast cancer cells contribute to HER2mediated radioresistance and molecular subtype conversion: clinical implications for serum HER2 in recurrent HER2negative breast cancer |
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https://doi.org/10.18632/oncotarget.23528
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| 5811-5822 |
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| Comparison of the modified lowdose cytarabine and etoposide with decitabine therapy for elderly acute myeloid leukemia patients unfit for intensive chemotherapy |
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https://doi.org/10.18632/oncotarget.23629
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| 5823-5833 |
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| The influence of chemotherapy on adenosineproducing B cells in patients with head and neck squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.23533
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| 5834-5847 |
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| High RAC3 expression levels are required for induction and maintaining of cancer cell stemness |
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https://doi.org/10.18632/oncotarget.23635
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| 5848-5860 |
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| Activation of Grm1 expression by mutated BRaf V600E in vitro and in vivo |
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https://doi.org/10.18632/oncotarget.23637
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| 5861-5875 |
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| Inhibition of NFκB prevents the acidic bileinduced oncogenic mRNA phenotype in human hypopharyngeal cells |
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https://doi.org/10.18632/oncotarget.23143
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| 5876-5891 |
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| YAPassociated chromosomal instability and cholangiocarcinoma in mice |
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https://doi.org/10.18632/oncotarget.23638
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| 5892-5905 |
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| Zinc finger protein 598 inhibits cell survival by promoting UVinduced apoptosis |
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https://doi.org/10.18632/oncotarget.23643
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| 5906-5918 |
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| The transcriptional and mutational landscapes of lipid metabolismrelated genes in colon cancer |
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https://doi.org/10.18632/oncotarget.23592
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| 5919-5930 |
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| Pathological and functional significance of Semaphorin5A in pancreatic cancer progression and metastasis |
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https://doi.org/10.18632/oncotarget.23644
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| 5931-5943 |
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| Identification and characterization of novel enhanced cell penetrating peptides for anticancer cargo delivery |
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https://doi.org/10.18632/oncotarget.23179
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| 5944-5957 |
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| A dock derived compound against laminin receptor 37 LR exhibits anticancer properties in a prostate cancer cell line model |
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https://doi.org/10.18632/oncotarget.23236
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| 5958-5978 |
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| Src is the primary target of aripiprazole an atypical antipsychotic drug in its antitumor action |
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https://doi.org/10.18632/oncotarget.23192
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| 5979-5992 |
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| Inhibition of IAP’s and activation of p53 leads to caspasedependent apoptosis in gastric cancer cells treated with Scutellarein |
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https://doi.org/10.18632/oncotarget.23202
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| 5993-6006 |
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| Assessing tumor molecular profiling to guide treatments for patients with advanced female genital tract malignancy |
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https://doi.org/10.18632/oncotarget.23675
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| 6007-6014 |
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| Human papillomavirus E7 oncoprotein expression by keratinocytes alters the cytotoxic mechanisms used by CD8 T cells |
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https://doi.org/10.18632/oncotarget.23210
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| 6015-6027 |
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| Epigenetic changes found in uterine decidual and placental tissues can also be found in the breast cancer microenvironment of the same unique patient: description and potential interpretations |
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https://doi.org/10.18632/oncotarget.23488
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| 6028-6041 |
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| Combination of a thioxodihydroquinazolinone with cisplatin eliminates ovarian cancer stem celllike cells CSCLCs and shows preclinical potential |
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https://doi.org/10.18632/oncotarget.23679
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| 6042-6054 |
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| Rapid development of myeloproliferative neoplasm in mice with Ptpn11D61Y mutation and haploinsufficient for Dnmt3a |
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https://doi.org/10.18632/oncotarget.23680
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| 6055-6061 |
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| [Neratinib + Valproate] exposure permanently reduces ERBB1 and RAS expression in 4T1 mammary tumors and enhances M1 macrophage infiltration |
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https://doi.org/10.18632/oncotarget.23681
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| 6062-6074 |
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| Expression of Wntsignaling pathway genes and their associations with miRNAs in colorectal cancer |
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https://doi.org/10.18632/oncotarget.23636
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| 6075-6085 |
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| Construction of key signal regulatory network in metastatic colorectal cancer |
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https://doi.org/10.18632/oncotarget.23710
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| 6086-6094 |
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| Type IIB DNA topoisomerase is downregulated by trastuzumab and doxorubicin to synergize cardiotoxicity |
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https://doi.org/10.18632/oncotarget.23543
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| 6095-6108 |
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| Characterization and metabolic synthetic lethal testing in a new model of SDHloss familial pheochromocytoma and paraganglioma |
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https://doi.org/10.18632/oncotarget.23639
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| 6109-6127 |
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| Drp1/Fis1 interaction mediates mitochondrial dysfunction bioenergetic failure and cognitive decline in Alzheimer's disease |
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https://doi.org/10.18632/oncotarget.23640
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| 6128-6143 |
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| Natural and molecular history of prolactinoma: insights from a Prlr–/– mouse model |
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https://doi.org/10.18632/oncotarget.23713
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| 6144-6155 |
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| Cellcell fusion as a mechanism of DNA exchange in cancer |
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https://doi.org/10.18632/oncotarget.23715
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| 6156-6173 |
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| Combined inhibition of CDK and HDAC as a promising therapeutic strategy for both cutaneous and uveal metastatic melanoma |
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https://doi.org/10.18632/oncotarget.23485
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| 6174-6187 |
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| Translational study reveals a twofaced role of RBM3 in pancreatic cancer and suggests its potential value as a biomarker for improved patient stratification |
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https://doi.org/10.18632/oncotarget.23486
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| 6188-6200 |
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| The presence of PD1 positive tumor infiltrating lymphocytes in triple negative breast cancers is associated with a favorable outcome of disease |
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https://doi.org/10.18632/oncotarget.23717
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| 6201-6212 |
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| Near infrared fluorescence imaging of EGFR expression in vivo using IRDye800CWnimotuzumab |
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https://doi.org/10.18632/oncotarget.23557
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| 6213-6227 |
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| Gene aberration profile of tumors of adolescent and young adult females |
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https://doi.org/10.18632/oncotarget.23765
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| 6228-6237 |
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| Prognostic significance of heparanase expression in primary and metastatic breast carcinoma |
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https://doi.org/10.18632/oncotarget.23560
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| 6238-6244 |
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| Determination of candidate metabolite biomarkers associated with recurrence of HCVrelated hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.23500
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| 6245-6258 |
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| 2Amino3methylcarboxy5heptylthiophene TJ191 is a selective anticancer small molecule that targets low TβRIIIexpressing malignant Tcell leukemia/lymphoma cells |
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https://doi.org/10.18632/oncotarget.23501
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| 6259-6269 |
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| Activation of p53 and destabilization of androgen receptor by combinatorial inhibition of MDM2 and MDMX in prostate cancer cells |
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https://doi.org/10.18632/oncotarget.23569
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| 6270-6281 |
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| LIMD1 is induced by and required for LMP1 signaling and protects EBVtransformed cells from DNA damageinduced cell death |
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https://doi.org/10.18632/oncotarget.23676
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| 6282-6297 |
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| The possible existence of occult metastasis in patients with ovarian clearcell carcinoma who underwent complete resection without any residual tumours |
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https://doi.org/10.18632/oncotarget.23921
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| 6298-6307 |
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| A lethal synergy induced by phellinus linteus and camptothecin11 in colon cancer cells |
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https://doi.org/10.18632/oncotarget.23918
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| 6308-6319 |
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| Interleukin 8 activity influences the efficacy of adenoviral oncolytic immunotherapy in cancer patients |
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https://doi.org/10.18632/oncotarget.23967
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| 6320-6335 |
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| Quantitative radiomic profiling of glioblastoma represents transcriptomic expression |
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https://doi.org/10.18632/oncotarget.23975
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| 6336-6345 |
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| Complement C4dspecific antibodies for the diagnosis of lung cancer |
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https://doi.org/10.18632/oncotarget.23690
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| 6346-6355 |
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| Effects of a small molecule Rspondin1 substitute RS246204 on a mouse intestinal organoid culture |
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https://doi.org/10.18632/oncotarget.23721
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| 6356-6368 |
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| Differential tumor biological role of the tumor suppressor KAI1 and its splice variant in human breast cancer cells |
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https://doi.org/10.18632/oncotarget.23968
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| 6369-6390 |
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| Effects of interactions between common genetic variants and alcohol consumption on colorectal cancer risk |
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https://doi.org/10.18632/oncotarget.23997
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| 6391-6401 |
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| DAPK and CIP2A are involved in GAS6/AXLmediated Schwann cell proliferation in a rat model of bilateral cavernous nerve injury |
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https://doi.org/10.18632/oncotarget.23978
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| 6402-6415 |
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| MYCfamily protein overexpression and prominent nucleolar formation represent prognostic indicators and potential therapeutic targets for aggressive highMKI neuroblastomas: a report from the children’s oncology group |
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https://doi.org/10.18632/oncotarget.23740
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| 6416-6432 |
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| TGFβ2induced EMT is dampened by inhibition of autophagy and TNFα treatment |
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https://doi.org/10.18632/oncotarget.23942
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| 6433-6449 |
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| Lysinespecific demethylase 1 inhibitors prevent teratoma development from human induced pluripotent stem cells |
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https://doi.org/10.18632/oncotarget.24030
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| 6450-6462 |
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| Intravesicular epidermal growth factor receptor subject to retrograde trafficking drives epidermal growth factordependent migration |
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https://doi.org/10.18632/oncotarget.23766
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| 6463-6477 |
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| SNParray lesions in core binding factor acute myeloid leukemia |
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https://doi.org/10.18632/oncotarget.24031
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| 6478-6489 |
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| 3DPrinted masks as a new approach for immobilization in radiotherapy – a study of positioning accuracy |
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https://doi.org/10.18632/oncotarget.24032
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| 6490-6498 |
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| Deciphering microRNA targets in pancreatic cancer using miRComb R package |
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https://doi.org/10.18632/oncotarget.24034
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| 6499-6517 |
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| Cysts mark the early stage of metastatic tumor development in nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.23785
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| 6518-6535 |
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| T cell infiltration into Ewing sarcomas is associated with local expression of immuneinhibitory HLAG |
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https://doi.org/10.18632/oncotarget.23815
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| 6536-6549 |
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| Boolean analysis identifies CD38 as a biomarker of aggressive localized prostate cancer |
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https://doi.org/10.18632/oncotarget.23973
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| 6550-6561 |
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| mTOR inhibition enhances efficacy of dasatinib in ABLrearranged Phlike BALL |
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https://doi.org/10.18632/oncotarget.24020
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| 6562-6571 |
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| Impact of LMP7 rs2071543 gene polymorphism in increasing cancer risk: evidence from a metaanalysis and trial sequential analysis |
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https://doi.org/10.18632/oncotarget.23547
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| 6572-6585 |
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| A metaanalysis on Omega3 supplements in preventing recurrence of atrial fibrillation |
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https://doi.org/10.18632/oncotarget.23783
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| 6586-6594 |
Clinical Research Papers
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| An integrated analysis of hyponatremia in cancer patients receiving platinumbased or nonplatinumbased chemotherapy in clinical trials JCOG1405A |
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https://doi.org/10.18632/oncotarget.23536
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| 6595-6606 |
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| A multicenter retrospective analysis of elderly patients with acute myeloid leukemia who were treated with decitabine |
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https://doi.org/10.18632/oncotarget.23823
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| 6607-6614 |
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| The association between hydroxychloroquine treatment and cardiovascular morbidity among rheumatoid arthritis patients |
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https://doi.org/10.18632/oncotarget.23570
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| 6615-6622 |
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| Forty five percent of the Israeli population were infected with the influenza B Victoria virus during the winter season 2015–16 |
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https://doi.org/10.18632/oncotarget.23601
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| 6623-6629 |
Reviews
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| Implications of KRAS mutations in acquired resistance to treatment in NSCLC |
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https://doi.org/10.18632/oncotarget.23553
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| 6630-6643 |
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| Pancreatic cancer: disease dynamics tumor biology and the role of the microenvironment |
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https://doi.org/10.18632/oncotarget.24019
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| 6644-6651 |
Case Reports
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| Pneumatocele during sorafenib therapy: first report of an unusual complication |
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https://doi.org/10.18632/oncotarget.23599
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| 6652-6656 |
Corrections
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| Correction: The optimal time of initiation of renal replacement therapy in acute kidney injury: A metaanalysis |
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https://doi.org/10.18632/oncotarget.24254
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| 6657-6657 |
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| Correction: Aliskiren therapy in hypertension and cardiovascular disease: a systematic review and a metaanalysis |
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https://doi.org/10.18632/oncotarget.24255
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| 6658-6658 |
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