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Analysis of TAZ subcellular localization, Alexa flour 568-conjugated phalloidin to detect cytosolic F-actin. See Xiang et al.

Table of Contents

Reviews

Classification of current anticancer immunotherapies

https://doi.org/10.18632/oncotarget.2998

Lorenzo Galluzzi, Erika Vacchelli, José-Manuel Bravo-San Pedro, Aitziber Buqué, Laura Senovilla, Elisa Elena Baracco, Norma Bloy, Francesca Castoldi, Jean-Pierre Abastado, Patrizia Agostinis, Ron N. Apte, Fernando Aranda, Maha Ayyoub, Philipp Beckhove, Jean-Yves Blay, Laura Bracci, Anne Caignard, Chiara Castelli, Federica Cavallo, Estaban Celis, Vincenzo Cerundolo, Aled Clayton, Mario P. Colombo, Lisa Coussens, Madhav V. Dhodapkar, Alexander M. Eggermont, Douglas T. Fearon, Wolf H. Fridman, Jitka Fučíková, Dmitry I. Gabrilovich, Jérôme Galon, Abhishek Garg, François Ghiringhelli, Giuseppe Giaccone, Eli Gilboa, Sacha Gnjatic, Axel Hoos, Anne Hosmalin, Dirk Jäger, Pawel Kalinski, Klas Kärre, Oliver Kepp, Rolf Kiessling, John M. Kirkwood, Eva Klein, Alexander Knuth, Claire E. Lewis, Roland Liblau, Michael T. Lotze, Enrico Lugli, Jean-Pierre Mach, Fabrizio Mattei, Domenico Mavilio, Ignacio Melero, Cornelis J. Melief, Elizabeth A. Mittendorf, Lorenzo Moretta, Adekunke Odunsi, Hideho Okada, Anna Karolina Palucka, Marcus E. Peter, Kenneth J. Pienta, Angel Porgador, George C. Prendergast, Gabriel A. Rabinovich, Nicholas P. Restifo, Naiyer Rizvi, Catherine Sautès-Fridman, Hans Schreiber, Barbara Seliger, Hiroshi Shiku, Bruno Silva-Santos, Mark J. Smyth, Daniel E. Speiser, Radek Spisek, Pramod K. Srivastava, James E. Talmadge, Eric Tartour, Sjoerd H. Van Der Burg, Benoît J. Van Den Eynde, Richard Vile, Hermann Wagner, Jeffrey  S. Weber, Theresa L. Whiteside, Jedd D. Wolchok, Laurence Zitvogel, Weiping Zou, and Guido Kroemer
12472-12508
Abstract  |  PDF  |  Full Text  |  How to cite

Priority Research Papers

Hypoxiainducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype

https://doi.org/10.18632/oncotarget.2997

Lisha Xiang, Daniele M. Gilkes, Hongxia Hu, Naoharu Takano, Weibo Luo, Haiquan Lu, John W. Bullen, Debangshu Samanta, Houjie Liang, and Gregg L. Semenza
12509-12527
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A unifying gene signature for adenoid cystic cancer identifies parallel MYBdependent and MYBindependent therapeutic targets

https://doi.org/10.18632/oncotarget.2985

Ruli Gao, Chunxia Cao, Min Zhang, Maria-Cecilia Lopez, Yuanqing Yan, Zirong Chen, Yoshitsugu Mitani, Li Zhang, Maria Zajac-Kaye, Bin Liu, Lizi Wu, Rolf Renne, Henry V. Baker, Adel El-Naggar, and Frederic J. Kaye
12528-12542
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MYC regulates the noncoding transcriptome

https://doi.org/10.18632/oncotarget.3033

Jonathan R. Hart, Thomas C. Roberts, Marc S. Weinberg, Kevin V. Morris, and Peter K. Vogt
12543-12554
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Phosphorylation of Tip60 by p38α regulates p53mediated PUMA induction and apoptosis in response to DNA damage

https://doi.org/10.18632/oncotarget.2717

Yingxi Xu, Rong Liao, Na Li, Rong Xiang, and Peiqing Sun
12555-12572
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers: Gerotarget (Focus on Aging)

Higher mortality and impaired elimination of bacteria in aged mice after intracerebral infection with E coli are associated with an agerelated decline of microglia and macrophage functions

https://doi.org/10.18632/oncotarget.2709

Sandra Schütze, Sandra Ribes, Annika Kaufmann, Anja Manig, Jörg Scheffel, Sandra Redlich, Stephanie Bunkowski, Uwe-Karsten Hanisch, Wolfgang Brück, and Roland Nau
12573-12592
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers

Multidimensional analysis of gene expression reveals TGFB1I1induced EMT contributes to malignant progression of astrocytomas

https://doi.org/10.18632/oncotarget.2518

Yanwei Liu, Huimin Hu, Kuanyu Wang, Chuanbao Zhang, Yinyan Wang, Kun Yao, Pei Yang, Lei Han, Chunsheng Kang, Wei Zhang, and Tao Jiang
12593-12606
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

BRaf inhibitor vemurafenib in combination with temozolomide and fotemustine in the killing response of malignant melanoma cells

https://doi.org/10.18632/oncotarget.2610

Wynand P. Roos, Steve Quiros, Andrea Krumm, Stephanie Merz, Olivier Jérôme Switzeny, Markus Christmann, Carmen Loquai, and Bernd Kaina
12607-12620
Abstract  |  PDF  |  Full Text  |  How to cite

Neutrophils with protumor potential could efficiently suppress tumor growth after cytokine priming and in presence of normal NK cells

https://doi.org/10.18632/oncotarget.2181

Rui Sun, Jing Luo, Dong Li, Yu Shu, Chao Luo, Shan-Shan Wang, Jian Qin, Gui-Mei Zhang, and Zuo-Hua Feng
12621-12634
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The p53 transcriptional pathway is preserved in ATMmutated and NOTCH1mutated chronic lymphocytic leukemias

https://doi.org/10.18632/oncotarget.2211

Emmanouil Athanasakis, Elisabetta Melloni, Gian Matteo Rigolin, Chiara Agnoletto, Rebecca Voltan, Diego Vozzi, Elisa Piscianz, Ludovica Segat, Simeone Dal Monego, Antonio Cuneo, Paola Secchiero, and Giorgio Zauli
12635-12645
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PRK1/PKN1 controls migration and metastasis of androgenindependent prostate cancer cells

https://doi.org/10.18632/oncotarget.2653

Cordula A. Jilg, Anett Ketscher, Eric Metzger, Barbara Hummel, Dominica Willmann, Vanessa Rüsseler, Vanessa Drendel, Axel Imhof, Manfred Jung, Henriette Franz, Stefanie Hölz, Malte Krönig, Judith M. Müller, and Roland Schüle
12646-12664
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Androgen deprivation therapy prevents bladder cancer recurrence

https://doi.org/10.18632/oncotarget.2851

Koji Izumi, Masataka Taguri, Hiroshi Miyamoto, Yoshinori Hara, Takeshi Kishida, Kimio Chiba, Tetsuo Murai, Kotaro Hirai, Kotaro Suzuki, Kiyoshi Fujinami, Teiichiro Ueki, Koichi Udagawa, Kazuo Kitami, Masatoshi Moriyama, Yasuhide Miyoshi, Futoshi Tsuchiya, Ichiro Ikeda, Kazuki Kobayashi, Maho Sato, Satoshi Morita, Kazumi Noguchi, and Hiroji Uemura
12665-12674
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A role for BMPinduced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy

https://doi.org/10.18632/oncotarget.2564

Aaron Raymond, Bin Liu, Hong Liang, Ciamaio Wei, Michele Guindani, Yue Lu, Shoudan Liang, Lisa S. St. John, Jeff Molldrem, and Lalitha Nagarajan
12675-12693
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Ferroxitosis: A cell death from modulation of oxidative phosphorylation and PKM2dependent glycolysis in melanoma

https://doi.org/10.18632/oncotarget.3031

Alexander J. Lakhter, James Hamilton, Pierre C. Dagher, Suresh Mukkamala, Takashi Hato, X. Charlie Dong, Lindsey D. Mayo, Robert A. Harris, Anantha Shekhar, Mircea Ivan, Nickolay Brustovetsky, and Samisubbu R. Naidu
12694-12703
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Mislocalization of p27 to the cytoplasm of breast cancer cells confers resistance to antiHER2 targeted therapy

https://doi.org/10.18632/oncotarget.2871

Hui Zhao, Claire M. Faltermeier, Lori Mendelsohn, Peggy L. Porter, Bruce E. Clurman, and James M. Roberts
12704-12714
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tumor promoterinduced cellular senescence: cell cycle arrest followed by geroconversion

https://doi.org/10.18632/oncotarget.3011

Olga V. Leontieva, and Mikhail V. Blagosklonny
12715-12727
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The angular structure of ONC201 a TRAIL pathwayinducing compound determines its potent anticancer activity

https://doi.org/10.18632/oncotarget.2890

Jessica Wagner, Christina Leah Kline, Richard S. Pottorf, Bhaskara Rao Nallaganchu, Gary L. Olson, David T. Dicker, Joshua E. Allen, and Wafik S. El-Deiry
12728-12737
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Preclinical study of drug combinations that reduce breast cancer burden due to aberrant mTOR and metabolism promoted by LKB1 loss

https://doi.org/10.18632/oncotarget.2818

Rafaela Andrade-Vieira, Donna Goguen, Heidi A. Bentley, Chris V. Bowen, and Paola A. Marignani
12738-12752
Abstract  |  PDF  |  Full Text  |  How to cite

The role of AXL and the in vitro activity of the receptor tyrosine kinase inhibitor BGB324 in Ewing sarcoma

https://doi.org/10.18632/oncotarget.2648

Emmy D.G. Fleuren, Melissa H.S. Hillebrandt-Roeffen, Uta E. Flucke, D. Maroeska W.M. te Loo, Otto C. Boerman, Winette T.A. van der Graaf, and Yvonne M.H. Versleijen-Jonkers
12753-12768
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Endbinding 1 protein overexpression correlates with glioblastoma progression and sensitizes to Vincaalkaloids in vitro and in vivo

https://doi.org/10.18632/oncotarget.2646

Raphael Berges, Nathalie Baeza-Kallee, Emeline Tabouret, Olivier Chinot, Marie Petit, Anna Kruczynski, Dominique Figarella-Branger, Stephane Honore, and Diane Braguer
12769-12787
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Loss of compensatory prosurvival and antiapoptotic modulator IKKε sensitizes ovarian cancer cells to CHEK1 loss through an increased level of p21

https://doi.org/10.18632/oncotarget.2665

Marianne K. Kim, Dong J. Min, George Wright, Ian Goldlust, and Christina M. Annunziata
12788-12802
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Pilot study of p62 DNA vaccine in dogs with mammary tumors

https://doi.org/10.18632/oncotarget.2516

Vladimir Gabai, Franco M. Venanzi, Elena Bagashova, Oksana Rud, Francesca Mariotti, Cecilia Vullo, Giuseppe Catone, Michael Y. Sherman, Antonio Concetti, Andrey Chursov, Anastasia Latanova, Vita Shcherbinina, Victor Shifrin, and Alexander Shneider
12803-12810
Abstract  |  PDF  |  Full Text  |  How to cite

DEPTOR has growth suppression activity against pancreatic cancer cells

https://doi.org/10.18632/oncotarget.2659

Hua Li, Grace Y. Sun, Yongchao Zhao, Dafydd Thomas, Joel K. Greenson, Mark M. Zalupski, Edgar Ben-Josef, and Yi Sun
12811-12819
Abstract  |  PDF  |  Full Text  |  How to cite

TAp73 promotes anabolism

https://doi.org/10.18632/oncotarget.2667

Ivano Amelio, Alexey A. Antonov, Maria Valeria Catani, Renato Massoud, Francesca Bernassola, Richard A. Knight, Gerry Melino, and Alessandro Rufini
12820-12834
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Cotreatment with therapeutic neural stem cells expressing carboxyl esterase and CPT11 inhibit growth of primary and metastatic lung cancers in mice

https://doi.org/10.18632/oncotarget.2547

Bo-Rim Yi, Seung U. Kim, and Kyung-Chul Choi
12835-12848
Abstract  |  PDF  |  Full Text  |  How to cite

Inhibition of spontaneous and experimental lung metastasis of softtissue sarcoma by tumortargeting Salmonella typhimurium A1R

https://doi.org/10.18632/oncotarget.2561

Shinji Miwa, Yong Zhang, Kyung-Eun Baek, Fuminari Uehara, Shuya Yano, Mako Yamamoto, Yukihiko Hiroshima, Yasunori Matsumoto, Hiroaki Kimura, Katsuhiro Hayashi, Norio Yamamoto, Michael Bouvet, Hiroyuki Tsuchiya, Robert M. Hoffman, and Ming Zhao
12849-12861
Abstract  |  PDF  |  Full Text  |  How to cite

VER246608 a novel panisoform ATP competitive inhibitor of pyruvate dehydrogenase kinase disrupts Warburg metabolism and induces contextdependent cytostasis in cancer cells

https://doi.org/10.18632/oncotarget.2656

Jonathan D. Moore, Anna Staniszewska, Terence Shaw, Jalanie D’Alessandro, Ben Davis, Alan Surgenor, Lisa Baker, Natalia Matassova, James Murray, Alba Macias, Paul Brough, Mike Wood, and Patrick C. Mahon
12862-12876
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Metformin and salinomycin as the best combination for the eradication of NSCLC monolayer cells and their alveospheres cancer stem cells irrespective of EGFR KRAS EML4/ALK and LKB1 status

https://doi.org/10.18632/oncotarget.2657

Zhiguang Xiao, Bianca Sperl, Axel Ullrich, and Pjotr Knyazev
12877-12890
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Antiproliferative and gene expression actions of resveratrol in breast cancer cells in vitro

https://doi.org/10.18632/oncotarget.2632

Yu-Tang Chin, Meng-Ti Hsieh, Sheng-Huei Yang, Po-Wei Tsai, Shwu-Huey Wang, Ching-Chiung Wang, Yee-Shin Lee, Guei-Yun Cheng, Wei-Chun HuangFu, David London, Heng-Yuan Tang, Earl Fu, Yun Yen, Leroy F. Liu, Hung-Yun Lin, and Paul J. Davis
12891-12907
Abstract  |  PDF  |  Full Text  |  How to cite

MicroRNA expression patterns in the malignant progression of gliomas and a 5microRNA signature for prognosis

https://doi.org/10.18632/oncotarget.2679

Wei Yan, Rui Li, Yanwei Liu, Pei Yang, Zheng Wang, Chuanbao Zhang, Zhaoshi Bao, Wei Zhang, Yongping You, and Tao Jiang
12908-12915
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

AuroraA promotes chemoresistance in hepatocelluar carcinoma by targeting NFkappaB/microRNA21/PTEN signaling pathway

https://doi.org/10.18632/oncotarget.2682

Kai Zhang, Jing Chen, Dongqin Chen, Jiayuan Huang, Bing Feng, Siqi Han, Yitian Chen, Haizhu Song, Wei De, Ziman Zhu, Rui Wang, and Longbang Chen
12916-12935
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Involvement of metformin and AMPK in the radioresponse and prognosis of luminal versus basallike breast cancer treated with radiotherapy

https://doi.org/10.18632/oncotarget.2683

Yimin Zhang, Sarah J. Storr, Kerstie Johnson, Andrew R. Green, Emad A. Rakha, Ian O. Ellis, David A.L. Morgan, and Stewart G. Martin
12936-12949
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

LIGHT/TNFSF14 increases osteoclastogenesis and decreases osteoblastogenesis in multiple myelomabone disease

https://doi.org/10.18632/oncotarget.2633

Giacomina Brunetti, Rita Rizzi, Angela Oranger, Isabella Gigante, Giorgio Mori, Grazia Taurino, Teresa Mongelli, Graziana Colaianni, Adriana Di Benedetto, Roberto Tamma, Giuseppe Ingravallo, Anna Napoli, Maria Felicia Faienza, Anna Mestice, Paola Curci, Giorgina Specchia, Silvia Colucci, and Maria Grano
12950-12967
Abstract  |  PDF  |  Full Text  |  How to cite

Clinical Research Papers

Peripheral primitive neuroectodermal tumor: Dynamic CT MRI and clinicopathological characteristics analysis of 36 cases and review of the literature

https://doi.org/10.18632/oncotarget.2649

Yan Tan, Hui Zhang, Guo-lin Ma, En-hua Xiao, and Xiao-chun Wang
12968-12977
Abstract  |  PDF  |  Full Text  |  How to cite

Prognostic impact of a compartmentspecific angiogenic marker profile in patients with pancreatic cancer

https://doi.org/10.18632/oncotarget.2651

Christoph Kahlert, Maria Fiala, Gabriel Musso, Niels Halama, Sophia Keim, Massimiliano Mazzone, Felix Lasitschka, Mathieu Pecqueux, Fee Klupp, Thomas Schmidt, Nuh Rahbari, Sebastian Schölch, Christian Pilarsky, Alexis Ulrich, Martin Schneider, Juergen Weitz, and Moritz Koch
12978-12989
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite


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