Editorial

Anesthetics and epigenetics	Anesthetics and epigenetics
https://doi.org/10.18632/oncotarget.13143 Nilkantha Sen
78220-78221

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Serotonin and sleeppromoting neurons	Serotonin and sleeppromoting neurons
https://doi.org/10.18632/oncotarget.13419 Armelle Rancillac
78222-78223

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Perineuronal nets in neurodegeneration	Perineuronal nets in neurodegeneration
https://doi.org/10.18632/oncotarget.13420 Sighild Lemarchant, Sara Wojciechowski, and Jari Koistinaho
78224-78225

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Priority Research Papers

Hedgehog pathway dysregulation contributes to the pathogenesis of human gastrointestinal stromal tumors via GLImediated activation of KIT expression	Hedgehog pathway dysregulation contributes to the pathogenesis of human gastrointestinal stromal tumors via GLImediated activation of KIT expression
https://doi.org/10.18632/oncotarget.12909 Chih-Min Tang, Tracy E. Lee, Sabriya A. Syed, Adam M. Burgoyne, Stephanie Y. Leonard, Fei Gao, Jonathan C. Chan, Eileen Shi, Juliann Chmielecki, Deborah Morosini, Kai Wang, Jeffrey S. Ross, Michael L. Kendrick, Michael R. Bardsley, Martina De Siena, Junhao Mao, Olivier Harismendy, Tamas Ordog, and Jason K. Sicklick
78226-78241

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CPI17 drives oncogenic Ras signaling in human melanomas via EzrinRadixinMoesin family proteins	CPI17 drives oncogenic Ras signaling in human melanomas via EzrinRadixinMoesin family proteins
https://doi.org/10.18632/oncotarget.12919 Lars Björn Riecken, Ansgar Zoch, Ulrike Wiehl, Sabine Reichert, Ingmar Scholl, Yan Cui, Mirjana Ziemer, Ulf Anderegg, Christian Hagel, and Helen Morrison
78242-78254

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p73 expression is regulated by ribosomal protein RPL26 through mRNA translation and protein stability	p73 expression is regulated by ribosomal protein RPL26 through mRNA translation and protein stability
https://doi.org/10.18632/oncotarget.13126 Min Zhang, Jin Zhang, Wensheng Yan, and Xinbin Chen
78255-78268

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A randomized phase II trial comparing chemoimmunotherapy with or without bevacizumab in previously untreated patients with chronic lymphocytic leukemia	A randomized phase II trial comparing chemoimmunotherapy with or without bevacizumab in previously untreated patients with chronic lymphocytic leukemia
https://doi.org/10.18632/oncotarget.13412 Neil E. Kay, Paolo Strati, Betsy R. LaPlant, Jose F. Leis, Daniel Nikcevich, Timothy G. Call, Adam M. Pettinger, Connie E. Lesnick, Curtis A. Hanson, and Tait D. Shanafelt
78269-78280

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Research Papers: Gerotarget (Focus on Aging)

Azadiradione ameliorates polyglutamine expansion disease in Drosophila by potentiating DNA binding activity of heat shock factor 1	Azadiradione ameliorates polyglutamine expansion disease in Drosophila by potentiating DNA binding activity of heat shock factor 1
https://doi.org/10.18632/oncotarget.12930 Vinod K. Nelson, Asif Ali, Naibedya Dutta, Suvranil Ghosh, Manas Jana, Arnab Ganguli, Andrei Komarov, Soumyadip Paul, Vibha Dwivedi, Subhrangsu Chatterjee, Nihar R. Jana, Subhash C. Lakhotia, Gopal Chakrabarti, Anup K. Misra, Subhash C. Mandal, and Mahadeb Pal
78281-78296

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Expression of functional alternative telomerase RNA component gene in mouse brain and in motor neurons cells protects from oxidative stress	Expression of functional alternative telomerase RNA component gene in mouse brain and in motor neurons cells protects from oxidative stress
https://doi.org/10.18632/oncotarget.13049 Erez Eitan, Admoni Tamar, Grin Yossi, Refael Peleg, Alex Braiman, and Esther Priel
78297-78309

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Presence of lacunar infarctions is associated with the spatial navigation impairment in patients with mild cognitive impairment: a DTI study	Presence of lacunar infarctions is associated with the spatial navigation impairment in patients with mild cognitive impairment: a DTI study
https://doi.org/10.18632/oncotarget.13409 Yan-Feng Wu, Wen-Bo Wu, Qing-Ping Liu, Wen-Wen He, Hong Ding, Zuzana Nedelska, Jakub Hort, Bing Zhang, and Yun Xu
78310-78319

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Research Papers: Pathology

Sulfuretin promotes osteoblastic differentiation in primary cultured osteoblasts and in vivo bone healing	Sulfuretin promotes osteoblastic differentiation in primary cultured osteoblasts and in vivo bone healing
https://doi.org/10.18632/oncotarget.12460 Q-Schick Auh, Kyung-Ran Park, Hyung-Mun Yun, Hyun-Chang Lim, Ga-Hyun Kim, Dong-Sung Lee, Youn-Chul Kim, Hyuncheol Oh, and Eun-Cheol Kim
78320-78330

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Targeting EZH1 and EZH2 contributes to the suppression of fibrosisassociated genes by miR2143p in cardiac myofibroblasts	Targeting EZH1 and EZH2 contributes to the suppression of fibrosisassociated genes by miR2143p in cardiac myofibroblasts
https://doi.org/10.18632/oncotarget.13048 Wen-Si Zhu, Chun-Mei Tang, Zhen Xiao, Jie-Ning Zhu, Qiu-Xiong Lin, Yong-Heng Fu, Zhi-Qin Hu, Zhuo Zhang, Min Yang, Xi-Long Zheng, Shu-Lin Wu, and Zhi-Xin Shan
78331-78342

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Dysregulation of macrophage polarization is associated with the metastatic process in osteosarcoma	Dysregulation of macrophage polarization is associated with the metastatic process in osteosarcoma
https://doi.org/10.18632/oncotarget.13055 Clotilde Dumars, Jean-Michel Ngyuen, Aurélie Gaultier, Rachel Lanel, Nadège Corradini, François Gouin, Dominique Heymann, and Marie-Françoise Heymann
78343-78354

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High frequency of clonal IG and Tcell receptor gene rearrangements in histiocytic and dendritic cell neoplasms	High frequency of clonal IG and Tcell receptor gene rearrangements in histiocytic and dendritic cell neoplasms
https://doi.org/10.18632/oncotarget.13058 Wenting Huang, Tian Qiu, Linshu Zeng, Bo Zheng, Jianming Ying, and Xiaoli Feng
78355-78362

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Novel mutations c28G>T pAla10Ser and c189G>T pGlu63Asp in WDR62 associated with early onset acanthosis and hyperkeratosis in a patient with autosomal recessive microcephaly type 2	Novel mutations c28G>T pAla10Ser and c189G>T pGlu63Asp in WDR62 associated with early onset acanthosis and hyperkeratosis in a patient with autosomal recessive microcephaly type 2
https://doi.org/10.18632/oncotarget.13279 Santasree Banerjee, Huishuang Chen, Hui Huang, Jing Wu, Zhiyun Yang, Weiping Deng, Dongna Chen, Jianlian Deng, Yan Su, Yang Li, Chao Wu, Ye Wang, Hao Zeng, Yiming Wang, and Xunhua Li
78363-78371

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Ischemic preconditioning attenuates ischemia/reperfusion injury in rat steatotic liver: role of heme oxygenase1mediated autophagy	Ischemic preconditioning attenuates ischemia/reperfusion injury in rat steatotic liver: role of heme oxygenase1mediated autophagy
https://doi.org/10.18632/oncotarget.13281 Anding Liu, Enshuang Guo, Jiankun Yang, Renlong Li, Yan Yang, Shenpei Liu, Jifa Hu, Xiaojing Jiang, Olaf Dirsch, Uta Dahmen, Jian Sun, and Mingwen Ouyang
78372-78386

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New conception for the development of hypertension in preeclampsia	New conception for the development of hypertension in preeclampsia
https://doi.org/10.18632/oncotarget.13410 Qinqin Gao, Jiaqi Tang, Na Li, Xiuwen Zhou, Xiaolin Zhu, Weisheng Li, Bailin Liu, Xueqin Feng, Jianying Tao, Bing Han, Hong Zhang, Miao Sun, and Zhice Xu
78387-78395

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Unique metabolic features of pancreatic cancer stroma: relevance to the tumor compartment prognosis and invasive potential	Unique metabolic features of pancreatic cancer stroma: relevance to the tumor compartment prognosis and invasive potential
https://doi.org/10.18632/oncotarget.11893 Erik S. Knudsen, Uthra Balaji, Elizaveta Freinkman, Peter McCue, and Agnieszka K. Witkiewicz
78396-78411

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Research Papers: Immunology

Gene therapy with plasmids encoding IFNβ or IFNα14 confers longterm resistance to HIV1 in humanized mice	Gene therapy with plasmids encoding IFNβ or IFNα14 confers longterm resistance to HIV1 in humanized mice
https://doi.org/10.18632/oncotarget.12512 Sojan Abraham, Jang-Gi Choi, Nora M. Ortega, Junli Zhang, Premlata Shankar, and N. Manjunath Swamy
78412-78420

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Research Papers

A novel microfluidic model can mimic organspecific metastasis of circulating tumor cells	A novel microfluidic model can mimic organspecific metastasis of circulating tumor cells
https://doi.org/10.18632/oncotarget.9382 Jing Kong, Yong Luo, Dong Jin, Fan An, Wenyuan Zhang, Lilu Liu, Jiao Li, Shimeng Fang, Xiaojie Li, Xuesong Yang, Bingcheng Lin, and Tingjiao Liu
78421-78432

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MiR99b5p expression and response to tyrosine kinase inhibitor treatment in clear cell renal cell carcinoma patients	MiR99b5p expression and response to tyrosine kinase inhibitor treatment in clear cell renal cell carcinoma patients
https://doi.org/10.18632/oncotarget.12618 Magdalena Lukamowicz-Rajska, Christiane Mittmann, Michael Prummer, Qing Zhong, Jens Bedke, Jörg Hennenlotter, Arnulf Stenzl, Axel Mischo, Svenja Bihr, Manuela Schmidinger, Ursula Vogl, Iris Blume, Christoph Karlo, Peter Schraml, and Holger Moch
78433-78447

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Clinical outcomes of advancedstage glassy cell carcinoma of the uterine cervix: a need for reappraisal	Clinical outcomes of advancedstage glassy cell carcinoma of the uterine cervix: a need for reappraisal
https://doi.org/10.18632/oncotarget.12905 Nara Yoon, Ji-Ye Kim, and Hyun-Soo Kim
78448-78454

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Endoplasmic reticulum stressinduced neuronal inflammatory response and apoptosis likely plays a key role in the development of diabetic encephalopathy	Endoplasmic reticulum stressinduced neuronal inflammatory response and apoptosis likely plays a key role in the development of diabetic encephalopathy
https://doi.org/10.18632/oncotarget.12925 Zhouguang Wang, Yan Huang, Yi Cheng, Yi Tan, Fenzan Wu, Jiamin Wu, Hongxue Shi, Hongyu Zhang, Xichong Yu, Hongchang Gao, Li Lin, Jun Cai, Jinsan Zhang, Xiaokun Li, Lu Cai, and Jian Xiao
78455-78472

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The role of Tks adaptor proteins in invadopodia formation growth and metastasis of melanoma	The role of Tks adaptor proteins in invadopodia formation growth and metastasis of melanoma
https://doi.org/10.18632/oncotarget.12954 Shinji Iizuka, Christopher Abdullah, Matthew D. Buschman, Begoña Diaz, and Sara A. Courtneidge
78473-78486

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A scoring system basing pathological parameters to predict regional lymph node metastasis after preoperative chemoradiotherapy for locally advanced rectal cancer: implication for local excision	A scoring system basing pathological parameters to predict regional lymph node metastasis after preoperative chemoradiotherapy for locally advanced rectal cancer: implication for local excision
https://doi.org/10.18632/oncotarget.10965 Xiao-Jie Wang, Pan Chi, Hui-Ming Lin, Xing-Rong Lu, Ying Huang, Zong-Bin Xu, Sheng-Hui Huang, Yan-Wu Sun, Dao-Xiong Ye, and Qian Yu
78487-78498

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A rational approach for cancer stemlike cell isolation and characterization using CD44 and prominin1CD133 as selection markers	A rational approach for cancer stemlike cell isolation and characterization using CD44 and prominin1CD133 as selection markers
https://doi.org/10.18632/oncotarget.12100 Yi-Jen Lee, Chang-Cheng Wu, Jhy-Wei Li, Chien-Chih Ou, Shih-Chung Hsu, Hsiu-Hsueh Tseng, Ming-Ching Kao, and Jah-Yao Liu
78499-78515

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Inhibition of autophagy inhibits the conversion of cardiac fibroblasts to cardiac myofibroblasts	Inhibition of autophagy inhibits the conversion of cardiac fibroblasts to cardiac myofibroblasts
https://doi.org/10.18632/oncotarget.12392 Shivika S. Gupta, Matthew R. Zeglinski, Sunil G. Rattan, Natalie M. Landry, Saeid Ghavami, Jeffrey T. Wigle, Thomas Klonisch, Andrew J. Halayko, and Ian M.C. Dixon
78516-78531

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Copy number gain of VCX Xlinked multicopy gene leads to cell proliferation and apoptosis during spermatogenesis	Copy number gain of VCX Xlinked multicopy gene leads to cell proliferation and apoptosis during spermatogenesis
https://doi.org/10.18632/oncotarget.12397 Juan Ji, Yufeng Qin, Rong Wang, Zhenyao Huang, Yan Zhang, Ran Zhou, Ling Song, Xiufeng Ling, Zhibin Hu, Dengshun Miao, Hongbing Shen, Yankai Xia, Xinru Wang, and Chuncheng Lu
78532-78540

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Analysis of angiogenesis related factors in glioblastoma peritumoral tissue and their derived cancer stem cells	Analysis of angiogenesis related factors in glioblastoma peritumoral tissue and their derived cancer stem cells
https://doi.org/10.18632/oncotarget.12398 Alessio D’Alessio, Gabriella Proietti, Gina Lama, Filippo Biamonte, Libero Lauriola, Umberto Moscato, Angelo Vescovi, Annunziato Mangiola, Cristiana Angelucci, and Gigliola Sica
78541-78556

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Simultaneous high expression of PLD1 and Sp1 predicts a poor prognosis for pancreatic ductal adenocarcinoma patients	Simultaneous high expression of PLD1 and Sp1 predicts a poor prognosis for pancreatic ductal adenocarcinoma patients
https://doi.org/10.18632/oncotarget.12447 Jiong Hu, Hai Hu, Jun-jie Hang, Hai-yan Yang, Zhi-yong Wang, Lei Wang, Dong-hui Chen, and Li-wei Wang
78557-78565

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Fatty acid synthase is a primary target of MiR15a and MiR161 in breast cancer	Fatty acid synthase is a primary target of MiR15a and MiR161 in breast cancer
https://doi.org/10.18632/oncotarget.12479 Jingxuan Wang, Xiao Zhang, Jinming Shi, Paul Cao, Meimei Wan, Qiang Zhang, Yunxuan Wang, Steven J. Kridel, Wennuan Liu, Jianfeng Xu, Qingyuan Zhang, and Guangchao Sui
78566-78576

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A functional signal profiling test for identifying a subset of HER2negative breast cancers with abnormally amplified HER2 signaling activity	A functional signal profiling test for identifying a subset of HER2negative breast cancers with abnormally amplified HER2 signaling activity
https://doi.org/10.18632/oncotarget.12480 Yao Huang, David J Burns, Benjamin E Rich, Ian A MacNeil, Abhijit Dandapat, Sajjad M. Soltani, Samantha Myhre, Brian F Sullivan, Leo T Furcht, Carol A Lange, Sara A Hurvitz, and Lance G Laing
78577-78590

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In Vivo magnetic resonance imaging of xenografted tumors using FTH1 reporter gene expression controlled by a teton switch	In Vivo magnetic resonance imaging of xenografted tumors using FTH1 reporter gene expression controlled by a teton switch
https://doi.org/10.18632/oncotarget.12519 Xiaoya He, Jinhua Cai, Hao Li, Bo Liu, Yong Qin, Yi Zhong, Longlun Wang, and Yifan Liao
78591-78604

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CCR10/CCL27 crosstalk contributes to failure of proteasomeinhibitors in multiple myeloma	CCR10/CCL27 crosstalk contributes to failure of proteasomeinhibitors in multiple myeloma
https://doi.org/10.18632/oncotarget.12522 Shanmugapriya Thangavadivel, Claudia Zelle-Rieser, Angelika Olivier, Benno Postert, Gerold Untergasser, Johann Kern, Andrea Brunner, Eberhard Gunsilius, Rainer Biedermann, Roman Hajek, Ludek Pour, Wolfgang Willenbacher, Richard Greil, and Karin Jöhrer
78605-78618

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Inhibition of calciumactivated chloride channel ANO1 suppresses proliferation and induces apoptosis of epithelium originated cancer cells	Inhibition of calciumactivated chloride channel ANO1 suppresses proliferation and induces apoptosis of epithelium originated cancer cells
https://doi.org/10.18632/oncotarget.12524 Lizhao Guan, Yan Song, Jian Gao, Jianjun Gao, and KeWei Wang
78619-78630

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Quantitative assessment of polymorphisms in H19 lncRNA and cancer risk: a metaanalysis of 13392 cases and 18893 controls	Quantitative assessment of polymorphisms in H19 lncRNA and cancer risk: a metaanalysis of 13392 cases and 18893 controls
https://doi.org/10.18632/oncotarget.12530 Minjie Chu, Weiyan Yuan, Shuangshuang Wu, Zhiquan Wang, Liping Mao, Tian Tian, Yihua Lu, Bowen Zhu, Yue Yang, Bin Wang, Haiquan Gao, Liying Jiang, and Xun Zhuang
78631-78639

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The microRNA miR33a suppresses IL6induced tumor progression by binding Twist in gallbladder cancer	The microRNA miR33a suppresses IL6induced tumor progression by binding Twist in gallbladder cancer
https://doi.org/10.18632/oncotarget.12693 Mingdi Zhang, Wei Gong, Bin Zuo, Bingfeng Chu, Zhaohui Tang, Yong Zhang, Yong Yang, Di Zhou, Mingzhe Weng, Yiyu Qin, Mingzhe Ma, Alex Jiang, Fei Ma, and Zhiwei Quan
78640-78652

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Mertk on tumor macrophages is a therapeutic target to prevent tumor recurrence following radiation therapy	Mertk on tumor macrophages is a therapeutic target to prevent tumor recurrence following radiation therapy
https://doi.org/10.18632/oncotarget.11823 Marka R. Crittenden, Jason Baird, David Friedman, Talicia Savage, Lauren Uhde, Alejandro Alice, Benjamin Cottam, Kristina Young, Pippa Newell, Cynthia Nguyen, Shelly Bambina, Gwen Kramer, Emmanuel Akporiaye, Anna Malecka, Andrew Jackson, and Michael J. Gough
78653-78666

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miR125b regulates differentiation and metabolic reprogramming of T cell acute lymphoblastic leukemia by directly targeting A20	miR125b regulates differentiation and metabolic reprogramming of T cell acute lymphoblastic leukemia by directly targeting A20
https://doi.org/10.18632/oncotarget.12018 Zixing Liu, Kelly R. Smith, Hung T. Khong, Jingshan Huang, Eun-Young Erin Ahn, Ming Zhou, and Ming Tan
78667-78679

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Downregulated resistin level in consequence of decreased neutrophil counts in untreated Grave's disease	Downregulated resistin level in consequence of decreased neutrophil counts in untreated Grave's disease
https://doi.org/10.18632/oncotarget.12019 Ying Peng, Yicheng Qi, Fengjiao Huang, Xinxin Chen, Yulin Zhou, Lei Ye, Weiqing Wang, Guang Ning, and Shu Wang
78680-78687

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Serum carboxypeptidaseA4 levels predict liver metastasis in colorectal carcinoma	Serum carboxypeptidaseA4 levels predict liver metastasis in colorectal carcinoma
https://doi.org/10.18632/oncotarget.12798 Lichao Sun, Chunguang Guo, Joseph Burnett, Zhihua Yang, Yuliang Ran, and Duxin Sun
78688-78697

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CD133+CD24lo defines a 5Fluorouracilresistant colon cancer stem celllike phenotype	CD133+CD24lo defines a 5Fluorouracilresistant colon cancer stem celllike phenotype
https://doi.org/10.18632/oncotarget.12168 Amy V. Paschall, Dafeng Yang, Chunwan Lu, Priscilla S. Redd, Jeong-Hyeon Choi, Christopher M. Heaton, Jeffrey R. Lee, Asha Nayak-Kapoor, and Kebin Liu
78698-78712

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SIN3A and SIN3B differentially regulate breast cancer metastasis	SIN3A and SIN3B differentially regulate breast cancer metastasis
https://doi.org/10.18632/oncotarget.12805 Monica J. Lewis, Jianzhong Liu, Emily Falk Libby, Minnkyong Lee, Nigel P.S. Crawford, and Douglas R. Hurst
78713-78725

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MFHAS1 promotes colorectal cancer progress by regulating polarization of tumorassociated macrophages via STAT6 signaling pathway	MFHAS1 promotes colorectal cancer progress by regulating polarization of tumorassociated macrophages via STAT6 signaling pathway
https://doi.org/10.18632/oncotarget.12807 Wankun Chen, Yajun Xu, Jing Zhong, Huihui Wang, Meilin Weng, Qian Cheng, Qichao Wu, Zhirong Sun, Hui Jiang, Minmin Zhu, Yu Ren, Pingbo Xu, Jiawei Chen, and Changhong Miao
78726-78735

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Optimization of radiotherapy for neck carcinoma metastasis from unknown primary sites: a metaanalysis	Optimization of radiotherapy for neck carcinoma metastasis from unknown primary sites: a metaanalysis
https://doi.org/10.18632/oncotarget.12852 Xiaomei Liu, Dianhe Li, Na Li, and Xiaoxia Zhu
78736-78746

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PICT1 triggers a prodeath autophagy through inhibiting rRNA transcription and AKT/mTOR/p70S6K signaling pathway	PICT1 triggers a prodeath autophagy through inhibiting rRNA transcription and AKT/mTOR/p70S6K signaling pathway
https://doi.org/10.18632/oncotarget.12288 Hongbo Chen, Yanhong Duo, Bo Hu, Zhiwei Wang, Fang Zhang, Hsiangi Tsai, Jianping Zhang, Lanzhen Zhou, Lijun Wang, Xinyu Wang, and Laiqiang Huang
78747-78763

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Fasudil an inhibitor of Rhoassociated coiledcoil kinase improves cognitive impairments induced by smoke exposure	Fasudil an inhibitor of Rhoassociated coiledcoil kinase improves cognitive impairments induced by smoke exposure
https://doi.org/10.18632/oncotarget.12853 Deng Xueyang, Ma Zhanqiang, Ma Chunhua, and Hao Kun
78764-78772

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A 5day cytoreductive chemotherapy followed by haploidentical hsct FA5BUCY as a tumorablative regimen improved the survival of patients with advanced hematological malignancies	A 5day cytoreductive chemotherapy followed by haploidentical hsct FA5BUCY as a tumorablative regimen improved the survival of patients with advanced hematological malignancies
https://doi.org/10.18632/oncotarget.12383 Ting Yang, Qiaoxian Lin, Jinhua Ren, Ping Chen, Xiaohong Yuan, Xiaofeng Luo, Tingbo Liu, Jing Zheng, Zhihong Zheng, Xiaoyun Zheng, Xinji Chen, Langhui Zhang, Hao Zheng, Zaisheng Chen, Xueling Hua, Shaohua Le, Jian Li, Zhizhe Chen, and Jianda Hu
78773-78786

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Metformin treatment reduces temozolomide resistance of glioblastoma cells	Metformin treatment reduces temozolomide resistance of glioblastoma cells
https://doi.org/10.18632/oncotarget.12859 Seung Ho Yang, Shenglan Li, Guangrong Lu, Haipeng Xue, Dong H. Kim, Jay-Jiguang Zhu, and Ying Liu
78787-78803

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Nuclear transcription factor Nrf2 suppresses prostate cancer cells growth and migration through upregulating ferroportin	Nuclear transcription factor Nrf2 suppresses prostate cancer cells growth and migration through upregulating ferroportin
https://doi.org/10.18632/oncotarget.12860 Dong Xue, Cuixing Zhou, Yunbo Shi, Hao Lu, Renfang Xu, and Xiaozhou He
78804-78812

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miR1281 inhibits the growth of glioblastoma multiforme and glioma stemlike cells via targeting BMI1 and E2F3	miR1281 inhibits the growth of glioblastoma multiforme and glioma stemlike cells via targeting BMI1 and E2F3
https://doi.org/10.18632/oncotarget.12385 Zheng-nan Shan, Rui Tian, Min Zhang, Zhao-hua Gui, Jing Wu, Min Ding, Xin-Fu Zhou, and Jie He
78813-78826

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KRAS mutations in blood circulating cellfree DNA: a pancreatic cancer casecontrol	KRAS mutations in blood circulating cellfree DNA: a pancreatic cancer casecontrol
https://doi.org/10.18632/oncotarget.12386 Florence Le Calvez-Kelm, Matthieu Foll, Magdalena B. Wozniak, Tiffany M. Delhomme, Geoffroy Durand, Priscilia Chopard, Maroulio Pertesi, Eleonora Fabianova, Zora Adamcakova, Ivana Holcatova, Lenka Foretova, Vladimir Janout, Maxime P. Vallee, Sabina Rinaldi, Paul Brennan, James D. McKay, Graham B. Byrnes, and Ghislaine Scelo
78827-78840

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Comparative analysis of protein interactome networks prioritizes candidate genes with cancer signatures	Comparative analysis of protein interactome networks prioritizes candidate genes with cancer signatures
https://doi.org/10.18632/oncotarget.12879 Yongsheng Li, Nidhi Sahni, and Song Yi
78841-78849

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Identification of a serum circulating lncRNA panel for the diagnosis and recurrence prediction of bladder cancer	Identification of a serum circulating lncRNA panel for the diagnosis and recurrence prediction of bladder cancer
https://doi.org/10.18632/oncotarget.12880 Weili Duan, Lutao Du, Xiumei Jiang, Rui Wang, Suzhen Yan, Yujiao Xie, Keqiang Yan, Qingliang Wang, Lili Wang, Xin Zhang, Hongwei Pan, Yongmei Yang, and Chuanxin Wang
78850-78858

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Metastasissuppressing NID2 an epigeneticallysilenced gene in the pathogenesis of nasopharyngeal carcinoma and esophageal squamous cell carcinoma	Metastasissuppressing NID2 an epigeneticallysilenced gene in the pathogenesis of nasopharyngeal carcinoma and esophageal squamous cell carcinoma
https://doi.org/10.18632/oncotarget.12889 Annie Wai Yeeng Chai, Arthur Kwok Leung Cheung, Wei Dai, Josephine Mun Yee Ko, Joseph Chok Yan Ip, Kwok Wah Chan, Dora Lai-Wan Kwong, Wai Tong Ng, Anne Wing Mui Lee, Roger Kai Cheong Ngan, Chun Chung Yau, Stewart Yuk Tung, Victor Ho Fun Lee, Alfred King-Yin Lam, Suja Pillai, Simon Law, and Maria Li Lung
78859-78871

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Premalignant alteration assessment in liverlike tissue derived from embryonic stem cells by aristolochic acid I exposure	Premalignant alteration assessment in liverlike tissue derived from embryonic stem cells by aristolochic acid I exposure
https://doi.org/10.18632/oncotarget.12424 Ke Jin, Dan-yan Zhu, Lu Li, Zheng-rong Mao, Bo-wen Wu, Yi-fan Wang, Zong-fu Pan, Lan-juan Li, Chun-sheng Xiang, Kun-kai Su, and Yi-jia Lou
78872-78882

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Selinexor a Selective Inhibitor of Nuclear Export SINE compound acts through NFκB deactivation and combines with proteasome inhibitors to synergistically induce tumor cell death	Selinexor a Selective Inhibitor of Nuclear Export SINE compound acts through NFκB deactivation and combines with proteasome inhibitors to synergistically induce tumor cell death
https://doi.org/10.18632/oncotarget.12428 Trinayan Kashyap, Christian Argueta, Amro Aboukameel, Thaddeus John Unger, Boris Klebanov, Ramzi M. Mohammad, Irfana Muqbil, Asfar S. Azmi, Claire Drolen, William Senapedis, Margaret Lee, Michael Kauffman, Sharon Shacham, and Yosef Landesman
78883-78895

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XPO1 inhibitor combination therapy with bortezomib or carfilzomib induces nuclear localization of IκBα and overcomes acquired proteasome inhibitor resistance in human multiple myeloma	XPO1 inhibitor combination therapy with bortezomib or carfilzomib induces nuclear localization of IκBα and overcomes acquired proteasome inhibitor resistance in human multiple myeloma
https://doi.org/10.18632/oncotarget.12969 Joel G. Turner, Trinayan Kashyap, Jana L. Dawson, Juan Gomez, Alexis A. Bauer, Steven Grant, Yun Dai, Kenneth H. Shain, Mark Meads, Yosef Landesman, and Daniel M. Sullivan
78896-78909

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cMyc is regulated by HIF2α in chronic hypoxia and influences sensitivity to 5FU in colon cancer	cMyc is regulated by HIF2α in chronic hypoxia and influences sensitivity to 5FU in colon cancer
https://doi.org/10.18632/oncotarget.12911 Liangjing Wang, Meng Xue, and Daniel C. Chung
78910-78917

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DDR2 overexpression in urothelial carcinoma indicates an unfavorable prognosis: a large cohort study	DDR2 overexpression in urothelial carcinoma indicates an unfavorable prognosis: a large cohort study
https://doi.org/10.18632/oncotarget.12912 Meng-Chen Tsai, Wei-Ming Li, Chun-Nung Huang, Hung-Lung Ke, Ching-Chia Li, Hsin-Chih Yeh, Ti-Chun Chan, Peir-In Liang, Bi-Wen Yeh, Wen-Jeng Wu, Sher-Wei Lim, and Chien-Feng Li
78918-78931

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Transcriptional upregulation of cMET is associated with invasion and tumor budding in colorectal cancer	Transcriptional upregulation of cMET is associated with invasion and tumor budding in colorectal cancer
https://doi.org/10.18632/oncotarget.12933 Conor A. Bradley, Philip D. Dunne, Victoria Bingham, Stephen McQuaid, Hajrah Khawaja, Stephanie Craig, Jackie James, Wendy L. Moore, Darragh G. McArt, Mark Lawler, Sonali Dasgupta, Patrick G. Johnston, and Sandra Van Schaeybroeck
78932-78945

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Attenuation of cancerinitiating cells stemness properties by abrogating S100A4 calcium binding ability in head and neck cancers	Attenuation of cancerinitiating cells stemness properties by abrogating S100A4 calcium binding ability in head and neck cancers
https://doi.org/10.18632/oncotarget.12935 Li-Hao Cheng, Kai-Feng Hung, Tung-Fu Huang, Hsin-Pei Hsieh, Shu-Ying Wang, Chih-Yang Huang, and Jeng-Fan Lo
78946-78957

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Mitotic arrestinduced phosphorylation of Mcl1 revisited using twodimensional gel electrophoresis and phosphoproteomics: nine phosphorylation sites identified	Mitotic arrestinduced phosphorylation of Mcl1 revisited using twodimensional gel electrophoresis and phosphoproteomics: nine phosphorylation sites identified
https://doi.org/10.18632/oncotarget.12586 Rong Chu, Sarah E. Alford, Katherine Hart, Anisha Kothari, Samuel G. Mackintosh, Matthew R. Kovak, and Timothy C. Chambers
78958-78970

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The nuclear corepressor 1 and the thyroid hormone receptor β suppress breast tumor lymphangiogenesis	The nuclear corepressor 1 and the thyroid hormone receptor β suppress breast tumor lymphangiogenesis
https://doi.org/10.18632/oncotarget.12978 Olaia Martínez-Iglesias, David Olmeda, Elvira Alonso-Merino, Sara Gómez-Rey, Ana M. González-López, Enrique Luengo, María S. Soengas, José Palacios, Javier Regadera, and Ana Aranda
78971-78984

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The prevalence of EGFR mutation in patients with nonsmall cell lung cancer: a systematic review and metaanalysis	The prevalence of EGFR mutation in patients with nonsmall cell lung cancer: a systematic review and metaanalysis
https://doi.org/10.18632/oncotarget.12587 Yue-Lun Zhang, Jin-Qiu Yuan, Kai-Feng Wang, Xiao-Hong Fu, Xiao-Ran Han, Diane Threapleton, Zu-Yao Yang, Chen Mao, and Jin-Ling Tang
78985-78993

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Overexpression of stathmin promotes metastasis and growth of malignant solid tumors: a systemic review and metaanalysis	Overexpression of stathmin promotes metastasis and growth of malignant solid tumors: a systemic review and metaanalysis
https://doi.org/10.18632/oncotarget.12982 Rong Biaoxue, Liu Hua, Gao Wenlong, and Yang Shuanying
78994-79007

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Dietary iron intake and breast cancer risk: modulation by an antioxidant supplementation	Dietary iron intake and breast cancer risk: modulation by an antioxidant supplementation
https://doi.org/10.18632/oncotarget.12592 Abou Diallo, Mélanie Deschasaux, Valentin Partula, Paule Latino-Martel, Bernard Srour, Serge Hercberg, Pilar Galan, Philippine Fassier, Françoise Guéraud, Fabrice H. Pierre, and Mathilde Touvier
79008-79016

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ING4 suppresses tumor angiogenesis and functions as a prognostic marker in human colorectal cancer	ING4 suppresses tumor angiogenesis and functions as a prognostic marker in human colorectal cancer
https://doi.org/10.18632/oncotarget.12984 Yansu Chen, Yefei Huang, Pingfu Hou, Zhe Zhang, Yafei Zhang, Weimin Wang, Guixiang Sun, Lichun Xu, Jianwei Zhou, Jin Bai, and Junnian Zheng
79017-79031

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Antagonizing miR2185p attenuates Wnt signaling and reduces metastatic bone disease of triple negative breast cancer cells	Antagonizing miR2185p attenuates Wnt signaling and reduces metastatic bone disease of triple negative breast cancer cells
https://doi.org/10.18632/oncotarget.12593 Hanna Taipaleenmäki, Nicholas H. Farina, Andre J. van Wijnen, Janet L. Stein, Eric Hesse, Gary S. Stein, and Jane B. Lian
79032-79046

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Autophagy negatively regulates tumor cell proliferation through phosphorylation dependent degradation of the Notch1 intracellular domain	Autophagy negatively regulates tumor cell proliferation through phosphorylation dependent degradation of the Notch1 intracellular domain
https://doi.org/10.18632/oncotarget.12986 Ji-Seon Ahn, Eun-Jung Ann, Mi-Yeon Kim, Ji-Hye Yoon, Hye-Jin Lee, Eun-Hye Jo, Keesook Lee, Ji Shin Lee, and Hee-Sae Park
79047-79063

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Synergistic targeting of Sp1 a critical transcription factor for myeloma cell growth and survival by panobinostat and proteasome inhibitors	Synergistic targeting of Sp1 a critical transcription factor for myeloma cell growth and survival by panobinostat and proteasome inhibitors
https://doi.org/10.18632/oncotarget.12594 Ariunzaya Bat-Erdene, Hirokazu Miki, Asuko Oda, Shingen Nakamura, Jumpei Teramachi, Ryota Amachi, Hirofumi Tenshin, Masahiro Hiasa, Masami Iwasa, Takeshi Harada, Shiro Fujii, Kimiko Sogabe, Kumiko Kagawa, Sumiko Yoshida, Itsuro Endo, Kenichi Aihara, and Masahiro Abe
79064-79075

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Antitumor activity of curcumin is involved in downregulation of YAP/TAZ expression in pancreatic cancer cells	Antitumor activity of curcumin is involved in downregulation of YAP/TAZ expression in pancreatic cancer cells
https://doi.org/10.18632/oncotarget.12596 Xiuxia Zhou, Jingna Su, Shaoyan Feng, Lixia Wang, Xuyuan Yin, Jingzhe Yan, and Zhiwei Wang
79076-79088

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Radiosensitizing effect of lapatinib in human epidermal growth factor receptor 2positive breast cancer cells	Radiosensitizing effect of lapatinib in human epidermal growth factor receptor 2positive breast cancer cells
https://doi.org/10.18632/oncotarget.12597 Tosol Yu, Bong Jun Cho, Eun Jung Choi, Ji Min Park, Dan Hyo Kim, and In Ah Kim
79089-79100

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

GBM heterogeneity as a function of variable epidermal growth factor receptor variant III activity	GBM heterogeneity as a function of variable epidermal growth factor receptor variant III activity
https://doi.org/10.18632/oncotarget.12600 Olle R. Lindberg, Andrew McKinney, Jane R. Engler, Gayane Koshkakaryan, Henry Gong, Aaron E. Robinson, Andrew J. Ewald, Emmanuelle Huillard, C. David James, Annette M. Molinaro, Joseph T. Shieh, and Joanna J. Phillips
79101-79116

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Defective ciliogenesis in thyroid hürthle cell tumors is associated with increased autophagy	Defective ciliogenesis in thyroid hürthle cell tumors is associated with increased autophagy
https://doi.org/10.18632/oncotarget.12997 Junguee Lee, Shinae Yi, Yea Eun Kang, Joon Young Chang, Jung Tae Kim, Hae Joung Sul, Jong Ok Kim, Jin Man Kim, Joon Kim, Anna Maria Porcelli, Koon Soon Kim, and Minho Shong
79117-79130

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Therapeutic effects of umbilical cord blood plasma in a rat model of acute ischemic stroke	Therapeutic effects of umbilical cord blood plasma in a rat model of acute ischemic stroke
https://doi.org/10.18632/oncotarget.12998 Jongman Yoo, Han-Soo Kim, Jin-Ju Seo, Jang-Hyoun Eom, Seong-Mi Choi, Sanghyun Park, Dong-Wook Kim, and Dong-Youn Hwang
79131-79140

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Ubenimex attenuates acquired sorafenib resistance in renal cell carcinoma by inhibiting Akt signaling in a lipophagy associated mechanism	Ubenimex attenuates acquired sorafenib resistance in renal cell carcinoma by inhibiting Akt signaling in a lipophagy associated mechanism
https://doi.org/10.18632/oncotarget.13003 Shuai Liu, Mingwei Gao, Xiaoqing Wang, Sentai Ding, Jiaju Lv, Dexuan Gao, Zhiyang Wang, and Zhihong Niu
79141-79153

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Proteomic analysis reveals diverse proline hydroxylationmediated oxygensensing cellular pathways in cancer cells	Proteomic analysis reveals diverse proline hydroxylationmediated oxygensensing cellular pathways in cancer cells
https://doi.org/10.18632/oncotarget.12632 Tong Zhou, Luke Erber, Bing Liu, Yankun Gao, Hai-Bin Ruan, and Yue Chen
79154-79169

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Antimetastatic effect of the TM4SF5specific peptide vaccine and humanized monoclonal antibody on colon cancer in a mouse lung metastasis model	Antimetastatic effect of the TM4SF5specific peptide vaccine and humanized monoclonal antibody on colon cancer in a mouse lung metastasis model
https://doi.org/10.18632/oncotarget.13005 Guang Wu, Dongbum Kim, Byoung Kwon Park, Sangkyu Park, Ji-Hee Ha, Te Ha Kim, Avishekh Gautam, Jung Nam Kim, Su In Lee, Han-Bum Park, Yong-Sung Kim, Hyung-Joo Kwon, and Younghee Lee
79170-79186

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The antitumor role of NK cells in vivo preactivated and restimulated by interleukins in acute lymphoblastic leukemia	The antitumor role of NK cells in vivo preactivated and restimulated by interleukins in acute lymphoblastic leukemia
https://doi.org/10.18632/oncotarget.13007 Fengyan Jin, Hai Lin, Sujun Gao, Zheng Hu, Song Zuo, Liguang Sun, Chunhui Jin, Wei Li, and Yanping Yang
79187-79202

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Spatiotemporal regulation of EGFR signaling by the Eps15 homology domaincontaining protein 3 EHD3	Spatiotemporal regulation of EGFR signaling by the Eps15 homology domaincontaining protein 3 EHD3
https://doi.org/10.18632/oncotarget.13008 Mohamed Amessou, Abdul Shukkur Ebrahim, Ashok Dilly, Melvin Joseph, Marina Tabolina, Sahiti Chukkapalli, Louay Meroueh, Joseph T. Syed, Allison Liddane, Siera Lanae Lang, Ayad Al-Katib, and Mustapha Kandouz
79203-79216

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects with quinonecontaining compounds and antimicrotubule drugs	The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects with quinonecontaining compounds and antimicrotubule drugs
https://doi.org/10.18632/oncotarget.12640 Pei Y. Liu, Nicholas Sokolowski, Su T. Guo, Faraz Siddiqi, Bernard Atmadibrata, Thomas J. Telfer, Yuting Sun, Lihong Zhang, Denise Yu, Joshua Mccarroll, Bing Liu, Rui H. Yang, Xiang Y. Guo, Andrew E. Tee, Ken Itoh, Jenny Wang, Maria Kavallaris, Michelle Haber, Murray D. Norris, Belamy B. Cheung, Jennifer A. Byrne, David S. Ziegler, Glenn M. Marshall, Marcel E. Dinger, Rachel Codd, Xu D. Zhang, and Tao Liu
79217-79232

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genetic interactions between the hedgehog coreceptors Gas1 and Boc regulate cell proliferation during murine palatogenesis	Genetic interactions between the hedgehog coreceptors Gas1 and Boc regulate cell proliferation during murine palatogenesis
https://doi.org/10.18632/oncotarget.13011 Guilherme M. Xavier, Maisa Seppala, Spyridon N. Papageorgiou, Chen-Ming Fan, and Martyn T. Cobourne
79233-79246

Abstract  |  PDF  |  Full Text  |  How to cite

Resveratrol posttreatment protects against neonatal brain injury after hypoxiaischemia	Resveratrol posttreatment protects against neonatal brain injury after hypoxiaischemia
https://doi.org/10.18632/oncotarget.13018 Shulin Pan, Songlin Li, Yingying Hu, Hao Zhang, Yanlong Liu, Huai Jiang, Mingchu Fang, Zhengmao Li, Kebin Xu, Hongyu Zhang, Zhenlang Lin, and Jian Xiao
79247-79261

Abstract  |  PDF  |  Full Text  |  How to cite

Notch1WISP1 axis determines the regulatory role of mesenchymal stem cellderived stromal fibroblasts in melanoma metastasis	Notch1WISP1 axis determines the regulatory role of mesenchymal stem cellderived stromal fibroblasts in melanoma metastasis
https://doi.org/10.18632/oncotarget.13021 Hongwei Shao, Long Cai, Mecker Moller, Biju Issac, Leiming Zhang, Mark Owyong, Anna Elizabeth Moscowitz, Roberto Vazquez-Padron, Freddy Radtke, and Zhao-Jun Liu
79262-79273

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Differentially expressed miRNAs in triple negative breast cancer between AfricanAmerican and nonHispanic white women	Differentially expressed miRNAs in triple negative breast cancer between AfricanAmerican and nonHispanic white women
https://doi.org/10.18632/oncotarget.13024 Bruna Sugita, Mandeep Gill, Akanskha Mahajan, Anju Duttargi, Saurabh Kirolikar, Rodrigo Almeida, Kenny Regis, Olusayo L. Oluwasanmi, Fabio Marchi, Catalin Marian, Kepher Makambi, Bhaskar Kallakury, Laura Sheahan, Iglenir J. Cavalli, Enilze M. Ribeiro, Subha Madhavan, Simina Boca, Yuriy Gusev, and Luciane R. Cavalli
79274-79291

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Targeting heterogeneity of adrenocortical carcinoma: Evaluation and extension of preclinical tumor models to improve clinical translation	Targeting heterogeneity of adrenocortical carcinoma: Evaluation and extension of preclinical tumor models to improve clinical translation
https://doi.org/10.18632/oncotarget.12685 Constanze Hantel, Igor Shapiro, Giada Poli, Costanza Chiapponi, Martin Bidlingmaier, Martin Reincke, Michaela Luconi, Sara Jung, and Felix Beuschlein
79292-79304

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Lentivirusmediated RNAi knockdown of insulinlike growth factor1 receptor inhibits the growth and invasion of hepatocellular carcinoma via downregulating midkine expression	Lentivirusmediated RNAi knockdown of insulinlike growth factor1 receptor inhibits the growth and invasion of hepatocellular carcinoma via downregulating midkine expression
https://doi.org/10.18632/oncotarget.13027 Cai Qun Bie, Xu You Liu, Ming Rong Cao, Qiu Yan Huang, Hui Jun Tang, Min Wang, Guo Li Cao, Ting Zhuang Yi, Sheng Lan Wu, Wei Jie Xu, and Shao Hui Tang
79305-79318

Abstract  |  PDF  |  Full Text  |  How to cite

Downregulation of osteoprotegerin expression in metastatic colorectal carcinoma predicts recurrent metastasis and poor prognosis	Downregulation of osteoprotegerin expression in metastatic colorectal carcinoma predicts recurrent metastasis and poor prognosis
https://doi.org/10.18632/oncotarget.12686 Ahrim Moon, Sung-Im Do, Hyun-Soo Kim, and Youn-Wha Kim
79319-79326

Abstract  |  PDF  |  Full Text  |  How to cite

Preclinical activity of MBM5 in gastrointestinal cancer by inhibiting NEK2 kinase activity	Preclinical activity of MBM5 in gastrointestinal cancer by inhibiting NEK2 kinase activity
https://doi.org/10.18632/oncotarget.12687 Yanfen Fang, Yannan Kong, Jianbei Xi, Mengli Zhu, Tong Zhu, Tongtong Jiang, Wenhao Hu, Mingliang Ma, and Xiongwen Zhang
79327-79341

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

DNMT3B in vitro knockingdown is able to reverse embryonal rhabdomyosarcoma cell phenotype through inhibition of proliferation and induction of myogenic differentiation	DNMT3B in vitro knockingdown is able to reverse embryonal rhabdomyosarcoma cell phenotype through inhibition of proliferation and induction of myogenic differentiation
https://doi.org/10.18632/oncotarget.12688 Francesca Megiorni, Simona Camero, Simona Ceccarelli, Heather P. McDowell, Olga Mannarino, Francesco Marampon, Barry Pizer, Rajeev Shukla, Antonio Pizzuti, Cinzia Marchese, Anna Clerico, and Carlo Dominici
79342-79356

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Intravoxel incoherent motion IVIM in diffusionweighted imaging DWI for Hepatocellular carcinoma: correlation with histologic grade	Intravoxel incoherent motion IVIM in diffusionweighted imaging DWI for Hepatocellular carcinoma: correlation with histologic grade
https://doi.org/10.18632/oncotarget.12689 Vincenza Granata, Roberta Fusco, Orlando Catalano, Benedetta Guarino, Francesco Granata, Fabiana Tatangelo, Antonio Avallone, Mauro Piccirillo, Raffaele Palaia, Francesco Izzo, and Antonella Petrillo
79357-79364

Abstract  |  PDF  |  Full Text  |  How to cite

Association between miR199a rs74723057 and MET rs1621 polymorphisms and the risk of hepatocellular carcinoma	Association between miR199a rs74723057 and MET rs1621 polymorphisms and the risk of hepatocellular carcinoma
https://doi.org/10.18632/oncotarget.13033 Qianqian Wang, Xiangyuan Yu, Qiang Li, Linyuan Qin, Shengkui Tan, Xiaoyun Zeng, Xiaoqiang Qiu, Bo Tang, Junfei Jin, Weijia Liao, Moqin Qiu, Lijun Tan, Gaofeng He, Xiaomei Li, Songqing He, and Hongping Yu
79365-79371

Abstract  |  PDF  |  Full Text  |  How to cite

A combined gene expression and functional study reveals the crosstalk between NMyc and differentiationinducing microRNAs in neuroblastoma cells	A combined gene expression and functional study reveals the crosstalk between NMyc and differentiationinducing microRNAs in neuroblastoma cells
https://doi.org/10.18632/oncotarget.12676 Zhenze Zhao, Xiuye Ma, Spencer D. Shelton, Derek C. Sung, Monica Li, Daniel Hernandez, Maggie Zhang, Michael D. Losiewiz, Yidong Chen, Alexander Pertsemlidis, Xiaojie Yu, Yuanhang Liu, and Liqin Du
79372-79387

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ON 01910Na rigosertib inhibits PI3K/Akt pathway and activates oxidative stress signals in head and neck cancer cell lines	ON 01910Na rigosertib inhibits PI3K/Akt pathway and activates oxidative stress signals in head and neck cancer cell lines
https://doi.org/10.18632/oncotarget.12692 Anil Prasad, Nagina Khudaynazar, Ramana V. Tantravahi, Amanda M. Gillum, and Benjamin S. Hoffman
79388-79400

Abstract  |  PDF  |  Full Text  |  How to cite

Delivery of a peptidedrug conjugate targeting the blood brain barrier improved the efficacy of paclitaxel against glioma	Delivery of a peptidedrug conjugate targeting the blood brain barrier improved the efficacy of paclitaxel against glioma
https://doi.org/10.18632/oncotarget.12708 Ying Li, Xuemin Zheng, Min Gong, and Jianning Zhang
79401-79407

Abstract  |  PDF  |  Full Text  |  How to cite

Nearinfrared photoimmunotherapy with galactosyl serum albumin in a model of diffuse peritoneal disseminated ovarian cancer	Nearinfrared photoimmunotherapy with galactosyl serum albumin in a model of diffuse peritoneal disseminated ovarian cancer
https://doi.org/10.18632/oncotarget.12710 Toshiko Harada, Yuko Nakamura, Kazuhide Sato, Tadanobu Nagaya, Shuhei Okuyama, Fusa Ogata, Peter L. Choyke, and Hisataka Kobayashi
79408-79416

Abstract  |  PDF  |  Full Text  |  How to cite

Identification of DNAPKcs as a primary resistance factor of salinomycin in osteosarcoma cells	Identification of DNAPKcs as a primary resistance factor of salinomycin in osteosarcoma cells
https://doi.org/10.18632/oncotarget.12712 Yun-fang Zhen, Song-tao Li, Yun-rong Zhu, Xiao-dong Wang, Xiao-zhong Zhou, and Lun-qing Zhu
79417-79427

Abstract  |  PDF  |  Full Text  |  How to cite

Targeted NGS arrayCGH and patientderived tumor xenografts for precision medicine in advanced breast cancer: a singlecenter prospective study	Targeted NGS arrayCGH and patientderived tumor xenografts for precision medicine in advanced breast cancer: a singlecenter prospective study
https://doi.org/10.18632/oncotarget.12714 Anthony Gonçalves, François Bertucci, Arnaud Guille, Severine Garnier, José Adelaide, Nadine Carbuccia, Oliver Cabaud, Pascal Finetti, Serge Brunelle, Gilles Piana, Jeanne Tomassin-Piana, Maria Paciencia, Eric Lambaudie, Cornel Popovici, Renaud Sabatier, Carole Tarpin, Magali Provansal, Jean-Marc Extra, François Eisinger, Hagay Sobol, Patrice Viens, Marc Lopez, Christophe Ginestier, Emmanuelle Charafe-Jauffret, Max Chaffanet, and Daniel Birnbaum
79428-79441

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Effect of marital status on the survival of patients with hepatocellular carcinoma treated with surgical resection: an analysis of 13408 patients in the surveillance epidemiology and end results SEER database	Effect of marital status on the survival of patients with hepatocellular carcinoma treated with surgical resection: an analysis of 13408 patients in the surveillance epidemiology and end results SEER database
https://doi.org/10.18632/oncotarget.12722 Chao Wu, Ping Chen, Jian-Jun Qian, Sheng-Jie Jin, Jie Yao, Xiao-Dong Wang, Dou-Sheng Bai, and Guo-Qing Jiang
79442-79452

Abstract  |  PDF  |  Full Text  |  How to cite

Investigating the mechanism of hepatocellular carcinoma progression by constructing genetic and epigenetic networks using NGS data identification and big database mining method	Investigating the mechanism of hepatocellular carcinoma progression by constructing genetic and epigenetic networks using NGS data identification and big database mining method
https://doi.org/10.18632/oncotarget.13100 Cheng-Wei Li, Ping-Yao Chang, and Bor-Sen Chen
79453-79473

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Utilization of leukapheresis and CD4 positive selection in Treg isolation and the exvivo expansion for a clinical application in transplantation and autoimmune disorders	Utilization of leukapheresis and CD4 positive selection in Treg isolation and the exvivo expansion for a clinical application in transplantation and autoimmune disorders
https://doi.org/10.18632/oncotarget.13101 Karolina Gołąb, Randall Grose, Piotr Trzonkowski, Amittha Wickrema, Martin Tibudan, Natalia Marek-Trzonkowska, Sabrina Matosz, Julia Solomina, Diane Ostrega, J. Michael Millis, and Piotr Witkowski
79474-79484

Abstract  |  PDF  |  Full Text  |  How to cite

OutLyzer: software for extracting lowallelefrequency tumor mutations from sequencing background noise in clinical practice	OutLyzer: software for extracting lowallelefrequency tumor mutations from sequencing background noise in clinical practice
https://doi.org/10.18632/oncotarget.13103 Etienne Muller, Nicolas Goardon, Baptiste Brault, Antoine Rousselin, Germain Paimparay, Angelina Legros, Robin Fouillet, Olivia Bruet, Aurore Tranchant, Florian Domin, Chankannira San, Céline Quesnelle, Thierry Frebourg, Agathe Ricou, Sophie Krieger, Dominique Vaur, and Laurent Castera
79485-79493

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification of KLK10 as a therapeutic target to reverse trastuzumab resistance in breast cancer	Identification of KLK10 as a therapeutic target to reverse trastuzumab resistance in breast cancer
https://doi.org/10.18632/oncotarget.13104 Zhuo Wang, Beihong Ruan, Yi Jin, Yulong Zhang, Jiaqiu Li, Liyuan Zhu, Wenxia Xu, Lifeng Feng, Hongchuan Jin, and Xian Wang
79494-79502

Abstract  |  PDF  |  Full Text  |  How to cite

KRASmutation status dependent effect of zoledronic acid in human nonsmall cell cancer preclinical models	KRASmutation status dependent effect of zoledronic acid in human nonsmall cell cancer preclinical models
https://doi.org/10.18632/oncotarget.12806 István Kenessey, Krisztina Kói, Orsolya Horváth, Mihály Cserepes, Dávid Molnár, Vera Izsák, Judit Dobos, Balázs Hegedűs, József Tóvári, and József Tímár
79503-79514

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Deubiquitinase USP9X deubiquitinates βcatenin and promotes high grade glioma cell growth	Deubiquitinase USP9X deubiquitinates βcatenin and promotes high grade glioma cell growth
https://doi.org/10.18632/oncotarget.12819 Bo Yang, Shiming Zhang, Zhihao Wang, Chunxu Yang, Wen Ouyang, Fuxiang Zhou, Yunfeng Zhou, and Conghua Xie
79515-79525

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In pursuit of synergy: An investigation of the PI3K/mTOR/MEK cotargeted inhibition strategy in NSCLC	In pursuit of synergy: An investigation of the PI3K/mTOR/MEK cotargeted inhibition strategy in NSCLC
https://doi.org/10.18632/oncotarget.12755 Susan Heavey, Sinead Cuffe, Stephen Finn, Vincent Young, Ronan Ryan, Siobhan Nicholson, Niamh Leonard, Niall McVeigh, Martin Barr, Kenneth O’Byrne, and Kathy Gately
79526-79543

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WM130 preferentially inhibits hepatic cancer stemlike cells by suppressing AKT/GSK3β/βcatenin signaling pathway	WM130 preferentially inhibits hepatic cancer stemlike cells by suppressing AKT/GSK3β/βcatenin signaling pathway
https://doi.org/10.18632/oncotarget.12822 Chen-Xu Ni, Yang Qi, Jin Zhang, Ying Liu, Wei-Heng Xu, Jing Xu, Hong-Gang Hu, Qiu-Ye Wu, Yan Wang, and Jun-Ping Zhang
79544-79556

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Epigallocatechin3gallateEGCG suppresses melanoma cell growth and metastasis by targeting TRAF6 activity	Epigallocatechin3gallateEGCG suppresses melanoma cell growth and metastasis by targeting TRAF6 activity
https://doi.org/10.18632/oncotarget.12836 Jianglin Zhang, Zhou Lei, Zunnan Huang, Xu Zhang, Youyou Zhou, Zhongling Luo, Weiqi Zeng, Juan Su, Cong Peng, and Xiang Chen
79557-79571

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Stimulation of prolactin receptor induces STAT5 phosphorylation and cellular invasion in glioblastoma multiforme	Stimulation of prolactin receptor induces STAT5 phosphorylation and cellular invasion in glioblastoma multiforme
https://doi.org/10.18632/oncotarget.12840 Amira Alkharusi, Shengze Yu, Natalia Landázuri, Fahad Zadjali, Belghis Davodi, Thomas Nyström, Torbjörn Gräslund, Afsar Rahbar, and Gunnar Norstedt
79572-79583

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MicroRNA101 reverses temozolomide resistance by inhibition of GSK3β in glioblastoma	MicroRNA101 reverses temozolomide resistance by inhibition of GSK3β in glioblastoma
https://doi.org/10.18632/oncotarget.12861 Tian Tian, Ma Mingyi, Xia Qiu, and Yang Qiu
79584-79595

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DIRC3 and near NABP1 genetic polymorphisms are associated laryngeal squamous cell carcinoma patient survival	DIRC3 and near NABP1 genetic polymorphisms are associated laryngeal squamous cell carcinoma patient survival
https://doi.org/10.18632/oncotarget.12865 Zhen Shen, Wanli Ren, Yanxia Bai, Zhengshuai Chen, Jingjie Li, Bin Li, Tianbo Jin, Peilong Cao, and Yuan Shao
79596-79604

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Comparison of the expression and function of Lin28A and Lin28B in colon cancer	Comparison of the expression and function of Lin28A and Lin28B in colon cancer
https://doi.org/10.18632/oncotarget.12869 Tianzhen Wang, Yan He, Yuanyuan Zhu, Mingwei Chen, Mingjiao Weng, Chao Yang, Yan Zhang, Ning Ning, Ran Zhao, Weiwei Yang, Yinji Jin, Jing Li, Riju James Rajkumar Ezakiel Redpath1, Lei Zhang, Xiaoming Jin, Zhaohua Zhong, Fengmin Zhang, Yunwei Wei, Guomin Shen, Dong Wang, Ying Liu, Guangyu Wang, and Xiaobo Li
79605-79616

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miR31 affects colorectal cancer cells by inhibiting autophagy in cancerassociated fibroblasts	miR31 affects colorectal cancer cells by inhibiting autophagy in cancerassociated fibroblasts
https://doi.org/10.18632/oncotarget.12873 Xiaodong Yang, Xiaohui Xu, Junjia Zhu, Gang Zhou, Yong Wu, Yongyou Wu, Kui Zhao, Chungen Xing, Jianping Cao, Hong Zhu, Ming Li, Zhenyu Ye, and Wei Peng
79617-79628

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Multiple mutations of lung squamous cell carcinoma shared common mechanisms	Multiple mutations of lung squamous cell carcinoma shared common mechanisms
https://doi.org/10.18632/oncotarget.13190 Qianping Li, Junyi Hou, Zhaoyan Hu, Biao Gu, and Yan Shi
79629-79636

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Therapeutic efficacy of the bromodomain inhibitor OTX015/MK8628 in ALKpositive anaplastic large cell lymphoma: an alternative modality to overcome resistant phenotypes	Therapeutic efficacy of the bromodomain inhibitor OTX015/MK8628 in ALKpositive anaplastic large cell lymphoma: an alternative modality to overcome resistant phenotypes
https://doi.org/10.18632/oncotarget.12876 Michela Boi, Maria Todaro, Valentina Vurchio, Shao Ning Yang, John Moon, Ivo Kwee, Andrea Rinaldi, Heng Pan, Ramona Crescenzo, Mangeng Cheng, Leandro Cerchietti, Olivier Elemento, Maria E. Riveiro, Esteban Cvitkovic, Francesco Bertoni, Giorgio Inghirami, and the AIRC 5xMille consortium ‘Genetics-driven targeted management of lymphoid malignancies’
79637-79653

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

SIRT1 promotes metastasis of human osteosarcoma cells	SIRT1 promotes metastasis of human osteosarcoma cells
https://doi.org/10.18632/oncotarget.12916 Ning Zhang, Tao Xie, Miao Xian, Yi-Jie Wang, Heng-Yuan Li, Mei-Dan Ying, and Zhao-Ming Ye
79654-79669

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Enhancement of 5FU sensitivity by the proapoptotic rpL3 gene in p53 null colon cancer cells through combined polymer nanoparticles	Enhancement of 5FU sensitivity by the proapoptotic rpL3 gene in p53 null colon cancer cells through combined polymer nanoparticles
https://doi.org/10.18632/oncotarget.13216 Annapina Russo, Sara Maiolino, Valentina Pagliara, Francesca Ungaro, Fabiana Tatangelo, Alessandra Leone, Giulia Scalia, Alfredo Budillon, Fabiana Quaglia, and Giulia Russo
79670-79687

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Breast cancer cells obtain an osteomimetic feature via epithelialmesenchymal transition that have undergone BMP2/RUNX2 signaling pathway induction	Breast cancer cells obtain an osteomimetic feature via epithelialmesenchymal transition that have undergone BMP2/RUNX2 signaling pathway induction
https://doi.org/10.18632/oncotarget.12939 Cong-Cong Tan, Gui-Xi Li, Li-Duan Tan, Xin Du, Xiao-Qing Li, Rui He, Qing-Shan Wang, and Yu-Mei Feng
79688-79705

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Increased phosphorylation of eIF2α in chronic myeloid leukemia cells stimulates secretion of matrix modifying enzymes	Increased phosphorylation of eIF2α in chronic myeloid leukemia cells stimulates secretion of matrix modifying enzymes
https://doi.org/10.18632/oncotarget.12941 Paulina Podszywalow-Bartnicka, Anna Cmoch, Magdalena Wolczyk, Lukasz Bugajski, Marta Tkaczyk, Michal Dadlez, Margaret Nieborowska-Skorska, Antonis E. Koromilas, Tomasz Skorski, and Katarzyna Piwocka
79706-79721

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Inhibiting glutaminase in acute myeloid leukemia: metabolic dependency of selected AML subtypes	Inhibiting glutaminase in acute myeloid leukemia: metabolic dependency of selected AML subtypes
https://doi.org/10.18632/oncotarget.12944 Polina Matre, Juliana Velez, Rodrigo Jacamo, Yuan Qi, Xiaoping Su, Tianyu Cai, Steven M. Chan, Alessia Lodi, Shannon R. Sweeney, Helen Ma, Richard Eric Davis, Natalia Baran, Torsten Haferlach, Xiaohua Su, Elsa Renee Flores, Doriann Gonzalez, Sergej Konoplev, Ismael Samudio, Courtney DiNardo, Ravi Majeti, Aaron D. Schimmer, Weiqun Li, Taotao Wang, Stefano Tiziani, and Marina Konopleva
79722-79735

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Glypican5 suppresses EpithelialMesenchymal Transition of the lung adenocarcinoma by competitively binding to Wnt3a	Glypican5 suppresses EpithelialMesenchymal Transition of the lung adenocarcinoma by competitively binding to Wnt3a
https://doi.org/10.18632/oncotarget.12945 Siwei Wang, Mantang Qiu, Wenjia Xia, Youtao Xu, Qixing Mao, Jie Wang, Gaochao Dong, Lin Xu, Xin Yang, and Rong Yin
79736-79746

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Nickel chlorideinduced apoptosis via mitochondria and Fasmediated caspasedependent pathways in broiler chickens	Nickel chlorideinduced apoptosis via mitochondria and Fasmediated caspasedependent pathways in broiler chickens
https://doi.org/10.18632/oncotarget.12946 Hongrui Guo, Hengmin Cui, Jing Fang, Zhicai Zuo, Junliang Deng, Xun Wang, Ling Zhao, Bangyuan Wu, Kejie Chen, and Jie Deng
79747-79760

Abstract  |  PDF  |  Full Text  |  How to cite

Volatile oil from Saussurea lappa exerts antitumor efficacy by inhibiting epithelial growth factor receptor tyrosine kinasemediated signaling pathway in hepatocellular carcinoma	Volatile oil from Saussurea lappa exerts antitumor efficacy by inhibiting epithelial growth factor receptor tyrosine kinasemediated signaling pathway in hepatocellular carcinoma
https://doi.org/10.18632/oncotarget.12962 Xuejing Lin, Zhangxiao Peng, Xiaohui Fu, Chunying Liu, Yang Xu, Weidan Ji, Jianhui Fan, Lei Chen, Lin Fang, Yao Huang, and Changqing Su
79761-79773

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Plasma glutamate carboxypeptidase is a negative regulator in liver cancer metastasis	Plasma glutamate carboxypeptidase is a negative regulator in liver cancer metastasis
https://doi.org/10.18632/oncotarget.12967 Jae-Hye Lee, Hyun-Soo Cho, Jeong-Ju Lee, Soo Young Jun, Jun-Ho Ahn, Ju-Sik Min, Ji-Yong Yoon, Min-Hyuk Choi, Su-Jin Jeon, Jung Hwa Lim, Cho-Rok Jung, Dae-Soo Kim, Hyun-Taek Kim, Valentina M. Factor, Yun-Han Lee, Snorri S. Thorgeirsson, Cheol-Hee Kim, and Nam-Soon Kim
79774-79786

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The survival and clinicopathological differences between patients with stage IIIA and stage II rectal cancer: An analysis of 12036 patients in the SEER database	The survival and clinicopathological differences between patients with stage IIIA and stage II rectal cancer: An analysis of 12036 patients in the SEER database
https://doi.org/10.18632/oncotarget.12970 Ben Huang, Shaobo Mo, Liang Zhu, Tianhong Xu, and Guoxiang Cai
79787-79796

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Novel mutations in CRB1 gene identified in a chinese pedigree with retinitis pigmentosa by targeted capture and next generation sequencing	Novel mutations in CRB1 gene identified in a chinese pedigree with retinitis pigmentosa by targeted capture and next generation sequencing
https://doi.org/10.18632/oncotarget.12971 Lan Lu, Xizhen Wang, David Lo, Jingning Weng, xiaohong Liu, Juhua Yang, Fen He, Yun Wang, and Xuyang Liu
79797-79804

Abstract  |  PDF  |  Full Text  |  How to cite

MicroRNA206 attenuates the growth and angiogenesis in nonsmall cell lung cancer cells by blocking the 1433ζ/STAT3/HIF1α/VEGF signaling	MicroRNA206 attenuates the growth and angiogenesis in nonsmall cell lung cancer cells by blocking the 1433ζ/STAT3/HIF1α/VEGF signaling
https://doi.org/10.18632/oncotarget.12972 Dong Xue, Ye Yang, Yawei Liu, Peiwen Wang, Yi Dai, Qinqiang Liu, Lijun Chen, Jian Shen, Huanyu Ju, Yuan Li, and Zhenguo Tan
79805-79813

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Orthoreovirus outerfiber proteins are substrates for SUMOconjugating enzyme Ubc9	Orthoreovirus outerfiber proteins are substrates for SUMOconjugating enzyme Ubc9
https://doi.org/10.18632/oncotarget.12973 Fei Yu, Hao Wang, Longlong Wang, and Liqun Lu
79814-79827

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Recombinant oncolytic poliovirus PVSRIPO has potent cytotoxic and innate inflammatory effects mediating therapy in human breast and prostate cancer xenograft models	Recombinant oncolytic poliovirus PVSRIPO has potent cytotoxic and innate inflammatory effects mediating therapy in human breast and prostate cancer xenograft models
https://doi.org/10.18632/oncotarget.12975 Eda K. Holl, Michael C. Brown, David Boczkowski, Megan A. McNamara, Daniel J. George, Darell D. Bigner, Matthias Gromeier, and Smita K. Nair
79828-79841

Abstract  |  PDF  |  Full Text  |  How to cite

Synergistic effects of selective inhibitors targeting the PI3K/AKT/mTOR pathway or NUP214ABL1 fusion protein in human Acute Lymphoblastic Leukemia	Synergistic effects of selective inhibitors targeting the PI3K/AKT/mTOR pathway or NUP214ABL1 fusion protein in human Acute Lymphoblastic Leukemia
https://doi.org/10.18632/oncotarget.13035 Carolina Simioni, Simona Ultimo, Alberto M. Martelli, Giorgio Zauli, Daniela Milani, James A. McCubrey, Silvano Capitani, and Luca M. Neri
79842-79853

Abstract  |  PDF  |  Full Text  |  How to cite

TRIM71 suppresses tumorigenesis via modulation of Lin28Blet7HMGA2 signaling	TRIM71 suppresses tumorigenesis via modulation of Lin28Blet7HMGA2 signaling
https://doi.org/10.18632/oncotarget.13036 Jinlong Yin, Tae-Hoon Kim, Nayun Park, Daye Shin, Hae In Choi, Sungchan Cho, Jong Bae Park, and Jong Heon Kim
79854-79868

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

RSK2 activity mediates glioblastoma invasiveness and is a potential target for new therapeutics	RSK2 activity mediates glioblastoma invasiveness and is a potential target for new therapeutics
https://doi.org/10.18632/oncotarget.13084 Florian J. Sulzmaier, Shirley Young-Robbins, Pengfei Jiang, Dirk Geerts, Amanda M. Prechtl, Michelle L. Matter L. Matter, Santosh Kesari, and Joe W. Ramos
79869-79884

Abstract  |  PDF  |  Full Text  |  How to cite

Cellular effects of fluorodeoxyglucose: Global changes in the lipidome and alteration in intracellular transport	Cellular effects of fluorodeoxyglucose: Global changes in the lipidome and alteration in intracellular transport
https://doi.org/10.18632/oncotarget.13089 Simona Kavaliauskiene, Maria Lyngaas Torgersen, Anne Berit Dyve Lingelem, Tove Irene Klokk, Tuulia Lintonen, Helena Simolin, Kim Ekroos, Tore Skotland, and Kirsten Sandvig
79885-79900

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tumor necrosis factoralpha promoter polymorphism 308 G/A is not significantly associated with esophageal cancer risk: a metaanalysis	Tumor necrosis factoralpha promoter polymorphism 308 G/A is not significantly associated with esophageal cancer risk: a metaanalysis
https://doi.org/10.18632/oncotarget.13093 Ming Luo, Yuan Yang, Dongmei Luo, Liang Liu, Yuening Zhang, Feifan Xiao, Jingcheng Yang, Chengdong Zhang, Shen Fu, and Zhiguo Luo
79901-79913

Abstract  |  PDF  |  Full Text  |  How to cite

Interleukin13 suppresses interleukin10 via inhibiting A20 in peripheral B cells of patients with food allergy	Interleukin13 suppresses interleukin10 via inhibiting A20 in peripheral B cells of patients with food allergy
https://doi.org/10.18632/oncotarget.13107 Ming-yang Li, Min Zhu, En-qiang Linghu, Fan Feng, Bing Zhu, Cheng Wu, and Ming-zhou Guo
79914-79924

Abstract  |  PDF  |  Full Text  |  How to cite

CD99 triggering induces methuosis of Ewing sarcoma cells through IGF1R/RAS/Rac1 signaling	CD99 triggering induces methuosis of Ewing sarcoma cells through IGF1R/RAS/Rac1 signaling
https://doi.org/10.18632/oncotarget.13160 Maria Cristina Manara, Mario Terracciano, Caterina Mancarella, Marika Sciandra, Clara Guerzoni, Michela Pasello, Andrea Grilli, Nicoletta Zini, Piero Picci, Mario P. Colombo, Andrea Morrione, and Katia Scotlandi
79925-79942

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PDL1 promoter methylation is a prognostic biomarker for biochemical recurrencefree survival in prostate cancer patients following radical prostatectomy	PDL1 promoter methylation is a prognostic biomarker for biochemical recurrencefree survival in prostate cancer patients following radical prostatectomy
https://doi.org/10.18632/oncotarget.13161 Heidrun Gevensleben, Emily Eva Holmes, Diane Goltz, Jörn Dietrich, Verena Sailer, Jörg Ellinger, Dimo Dietrich, and Glen Kristiansen
79943-79955

Abstract  |  PDF  |  Full Text  |  How to cite

miR186 affects the proliferation invasion and migration of human gastric cancer by inhibition of Twist1	miR186 affects the proliferation invasion and migration of human gastric cancer by inhibition of Twist1
https://doi.org/10.18632/oncotarget.13182 Chunhong Cao, Deguang Sun, Liang Zhang, and Lei Song
79956-79963

Abstract  |  PDF  |  Full Text  |  How to cite

Motor activity of centromereassociated proteinE contributes to its localization at the center of the midbody to regulate cytokinetic abscission	Motor activity of centromereassociated proteinE contributes to its localization at the center of the midbody to regulate cytokinetic abscission
https://doi.org/10.18632/oncotarget.13206 Akihiro Ohashi, Momoko Ohori, and Kenichi Iwai
79964-79980

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Establishment of mitochondrial pyruvate carrier 1 MPC1 gene knockout mice with preliminary gene function analyses	Establishment of mitochondrial pyruvate carrier 1 MPC1 gene knockout mice with preliminary gene function analyses
https://doi.org/10.18632/oncotarget.13210 Xiaoli Li, Yaqing Li, Gaoyang Han, Xiaoran Li, Yasai Ji, Zhirui Fan, Yali Zhong, Jing Cao, Jing Zhao, Goscinski Mariusz, Mingzhi Zhang, Jianguo Wen, Jahn M. Nesland, and Zhenhe Suo
79981-79994

Abstract  |  PDF  |  Full Text  |  How to cite

Mitomycin C treatment induces resistance and enhanced migration via phosphorylated Akt in aggressive lung cancer cells	Mitomycin C treatment induces resistance and enhanced migration via phosphorylated Akt in aggressive lung cancer cells
https://doi.org/10.18632/oncotarget.13237 Cheng-Ying Shen, Li-Han Chen, Yu-Fen Lin, Liang-Chuan Lai, Eric Y. Chuang, and Mong-Hsun Tsai
79995-80007

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Biodegradable doubletargeted PTXmPEGPLGA nanoparticles for ultrasound contrast enhanced imaging and antitumor therapy in vitro	Biodegradable doubletargeted PTXmPEGPLGA nanoparticles for ultrasound contrast enhanced imaging and antitumor therapy in vitro
https://doi.org/10.18632/oncotarget.13243 Jing Ma, Ming Shen, Chang Song Xu, Ying Sun, You Rong Duan, and Lian Fang Du
80008-80018

Abstract  |  PDF  |  Full Text  |  How to cite

Diagnostic accuracy of DNA methylation for head and neck cancer varies by sample type and number of markers tested	Diagnostic accuracy of DNA methylation for head and neck cancer varies by sample type and number of markers tested
https://doi.org/10.18632/oncotarget.12219 Xu Ji, Chao Guan, Xuejun Jiang, and Hong Li
80019-80032

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

New combined microRNA and protein plasmatic biomarker panel for pancreatic cancer	New combined microRNA and protein plasmatic biomarker panel for pancreatic cancer
https://doi.org/10.18632/oncotarget.12406 Wei Yuan, Wanyan Tang, Yibin Xie, Shaoming Wang, Yingtai Chen, Jun Qi, Youlin Qiao, and Jie Ma
80033-80045

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinical Research Papers

Firstinhuman phase I clinical trial of RG7356 an antiCD44 humanized antibody in patients with advanced CD44expressing solid tumors	Firstinhuman phase I clinical trial of RG7356 an antiCD44 humanized antibody in patients with advanced CD44expressing solid tumors
https://doi.org/10.18632/oncotarget.11098 C. Willemien Menke-van der Houven van Oordt, Carlos Gomez-Roca, Carla van Herpen, Andrew L. Coveler, Devalingam Mahalingam, Henk M. W. Verheul, Winette T. A. van der Graaf, Randolph Christen, Dominik Rüttinger, Stefan Weigand, Michael A. Cannarile, Florian Heil, Michael Brewster, Antje-Christine Walz, Tapan K. Nayak, Ernesto Guarin, Valerie Meresse, and Christophe Le Tourneau
80046-80058

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Serological immune response against ADAM10 prodomain is associated with favourable prognosis in stage III colorectal cancer patients	Serological immune response against ADAM10 prodomain is associated with favourable prognosis in stage III colorectal cancer patients
https://doi.org/10.18632/oncotarget.11181 Sheila María Álvarez-Fernández, Marco Barbariga, Luca Cannizzaro, Carlo Vittorio Cannistraci, Laura Hurley, Alan Zanardi, Antonio Conti, Francesca Sanvito, Anna Innocenzi, Nicolò Pecorelli, Marco Braga, and Massimo Alessio
80059-80076

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Adjuvant radiation therapy in stage I seminoma: 20 years of oncologic results	Adjuvant radiation therapy in stage I seminoma: 20 years of oncologic results
https://doi.org/10.18632/oncotarget.11374 Francesca De Felice, Daniela Musio, Giovanni Luca Gravina, Francesco Marampon, and Vincenzo Tombolini
80077-80082

Abstract  |  PDF  |  Full Text  |  How to cite

Imatinib and polypharmacy in very old patients with chronic myeloid leukemia: effects on response rate toxicity and outcome	Imatinib and polypharmacy in very old patients with chronic myeloid leukemia: effects on response rate toxicity and outcome
https://doi.org/10.18632/oncotarget.11657 Alessandra Iurlo, Alessandro Nobili, Roberto Latagliata, Cristina Bucelli, Fausto Castagnetti, Massimo Breccia, Elisabetta Abruzzese, Daniele Cattaneo, Carmen Fava, Dario Ferrero, Antonella Gozzini, Massimiliano Bonifacio, Mario Tiribelli, Patrizia Pregno, Fabio Stagno, Paolo Vigneri, Mario Annunziata, Francesco Cavazzini, Gianni Binotto, Giovanna Mansueto, Sabina Russo, Franca Falzetti, Enrico Montefusco, Gabriele Gugliotta, Sergio Storti, Ada M. D’Addosio, Luigi Scaffidi, Laura Cortesi, Michele Cedrone, Antonella Russo Rossi, Paolo Avanzini, Endri Mauro, Antonio Spadea, Francesca Celesti, Gianfranco Giglio, Alessandro Isidori, Monica Crugnola, Elisabetta Calistri, Federica Sorà, Giovanna Rege-Cambrin, Simona Sica, Luigiana Luciano, Sara Galimberti, Ester M. Orlandi, Monica Bocchia, Mauro Tettamanti, Giuliana Alimena, Giuseppe Saglio, Gianantonio Rosti, Pier Mannuccio Mannucci, and Agostino Cortelezzi
80083-80090

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Radiation combined with temozolomide contraindicated for young adults diagnosed with anaplastic glioma	Radiation combined with temozolomide contraindicated for young adults diagnosed with anaplastic glioma
https://doi.org/10.18632/oncotarget.11756 Pei Yang, Chuanbao Zhang, Jinquan Cai, Gan You, Yinyan Wang, Xiaoguang Qiu, Shouwei Li, Chenxing Wu, Kun Yao, Wenbin Li, Xiaoxia Peng, Wei Zhang, and Tao Jiang
80091-80100

Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

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