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About The Cover
The cover for issue 36 of Oncotarget features Figure 7 (Schematic model of regulatory pathways involved in MYCN turnover) from Vaughan, et al.
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Table of Contents
Editorial: Autophagy and Cell Death
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| The gasderminD pore: Executor of pyroptotic cell death |
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https://doi.org/10.18632/oncotarget.11421
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| 57481-57482 |
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| RIPK3dependent cell death and inflammasome activation in FLT3ITD expressing LICs |
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https://doi.org/10.18632/oncotarget.11195
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| 57483-57484 |
Research Perspective: Pathology
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| Conditional ablation of HDAC3 in islet beta cells results in glucose intolerance and enhanced susceptibility to STZinduced diabetes |
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https://doi.org/10.18632/oncotarget.11295
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| 57485-57497 |
Research Perspective: Immunology
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| Kukoamine B promotes TLR4independent lipopolysaccharide uptake in murine hepatocytes |
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https://doi.org/10.18632/oncotarget.11292
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| 57498-57513 |
Priority Research Papers
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| NFIB overexpression cooperates with Rb/p53 deletion to promote small cell lung cancer |
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https://doi.org/10.18632/oncotarget.11583
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| 57514-57524 |
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| Inhibition of mTORkinase destabilizes MYCN and is a potential therapy for MYCNdependent tumors |
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https://doi.org/10.18632/oncotarget.10544
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| 57525-57544 |
Research Papers: Pathology
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| Chronic obstructive sleep apnea accelerates pulmonary remodeling via TGFβ/miR185/CoLA1 signaling in a canine model |
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https://doi.org/10.18632/oncotarget.11296
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| 57545-57555 |
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| Spatial learning and memory impairments are associated with increased neuronal activity in 5XFAD mouse as measured by manganeseenhanced magnetic resonance imaging |
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https://doi.org/10.18632/oncotarget.11353
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| 57556-57570 |
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| A novel polymerfree ciglitazonecoated vascular stent: in vivo and ex vivo analysis of stent endothelialization in a rabbit iliac artery model |
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https://doi.org/10.18632/oncotarget.11584
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| 57571-57580 |
Research Papers: Immunology
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| Identification of novel host biomarkers in plasma as candidates for the immunodiagnosis of tuberculosis disease and monitoring of tuberculosis treatment response |
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https://doi.org/10.18632/oncotarget.11420
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| 57581-57592 |
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| Downregulation of the phosphatase JKAP/DUSP22 in T cells as a potential new biomarker of systemic lupus erythematosus nephritis |
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https://doi.org/10.18632/oncotarget.11419
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| 57593-57605 |
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| Expression and regulation of immunemodulatory enzyme indoleamine 23dioxygenase IDO by human airway epithelial cells and its effect on T cell activation |
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https://doi.org/10.18632/oncotarget.11586
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| 57606-57617 |
Research Papers
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| Selenoprotein W redoxregulated Ca2+ channels correlate with selenium deficiencyinduced muscles Ca2+ leak |
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https://doi.org/10.18632/oncotarget.11459
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| 57618-57632 |
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| Fibroblast growth factor receptor 4 FGFR4 and fibroblast growth factor 19 FGF19 autocrine enhance breast cancer cells survival |
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https://doi.org/10.18632/oncotarget.9328
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| 57633-57650 |
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| Acquired savolitinib resistance in nonsmall cell lung cancer arises via multiple mechanisms that converge on METindependent mTOR and MYC activation |
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https://doi.org/10.18632/oncotarget.10859
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| 57651-57670 |
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| Cancer megafunds with in silico and in vitro validation: accelerating cancer drug discovery via financial engineering without financial crisis |
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https://doi.org/10.18632/oncotarget.9808
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| 57671-57678 |
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| Impaired 53BP1/RIF1 DSB mediated endprotection stimulates CtIPdependent end resection and switches the repair to PARP1dependent end joining in G1 |
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https://doi.org/10.18632/oncotarget.11023
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| 57679-57693 |
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| Circulating resistin levels and obesityrelated cancer risk: A metaanalysis |
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https://doi.org/10.18632/oncotarget.11034
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| 57694-57704 |
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| A novel multitarget RNAi adenovirus inhibits hepatoma cell proliferation migration and induction of angiogenesis |
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https://doi.org/10.18632/oncotarget.9531
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| 57705-57713 |
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| ATM protein is deficient in over 40% of lung adenocarcinomas |
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https://doi.org/10.18632/oncotarget.9757
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| 57714-57725 |
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| A cancer specific hypermethylation signature of the TERT promoter predicts biochemical relapse in prostate cancer: a retrospective cohort study |
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https://doi.org/10.18632/oncotarget.10639
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| 57726-57736 |
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| CD147 knockdown improves the antitumor efficacy of trastuzumab in HER2positive breast cancer cells |
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https://doi.org/10.18632/oncotarget.10252
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| 57737-57751 |
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| Honokiol suppresses lung tumorigenesis by targeting EGFR and its downstream effectors |
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https://doi.org/10.18632/oncotarget.10759
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| 57752-57769 |
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| Srclike adaptor protein 2 SLAP2 binds to and inhibits FLT3 signaling |
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https://doi.org/10.18632/oncotarget.10760
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| 57770-57782 |
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| Role of SATB2 in human pancreatic cancer: Implications in transformation and a promising biomarker |
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https://doi.org/10.18632/oncotarget.10860
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| 57783-57797 |
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| Her2 oncogene transformation enhances 5aminolevulinic acidmediated protoporphyrin IX production and photodynamic therapy response |
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https://doi.org/10.18632/oncotarget.11058
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| 57798-57810 |
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| Acute myeloid leukemia stem cell markers in prognosis and targeted therapy: potential impact of BMI1 TIM3 and CLL1 |
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https://doi.org/10.18632/oncotarget.11063
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| 57811-57820 |
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| UHRF1 regulates global DNA hypomethylation and is associated with poor prognosis in esophageal squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.11067
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| 57821-57831 |
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| PTEN expression is a prognostic marker for patients with nonsmall cell lung cancer: a systematic review and metaanalysis of the literature |
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https://doi.org/10.18632/oncotarget.11068
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| 57832-57840 |
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| Deletion of epidermal Rac1 inhibits HPV8 induced skin papilloma formation and facilitates HPV8 and UVlight induced skin carcinogenesis |
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https://doi.org/10.18632/oncotarget.11069
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| 57841-57850 |
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| Inhibition of PlexA1mediated brain tumor growth and tumorassociated angiogenesis using a transmembrane domain targeting peptide |
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https://doi.org/10.18632/oncotarget.11072
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| 57851-57865 |
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| KDM4B plays an important role in mitochondrial apoptosis by upregulating HAX1 expression in colorectal cancer |
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https://doi.org/10.18632/oncotarget.11077
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| 57866-57877 |
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| RSUME is implicated in tumorigenesis and metastasis of pancreatic neuroendocrine tumors |
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https://doi.org/10.18632/oncotarget.11081
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| 57878-57893 |
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| Sunitinib as salvage treatment including potent antitumor activity in carcinomatous ulcers for patients with multidrugresistant metastatic breast cancer |
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https://doi.org/10.18632/oncotarget.11082
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| 57894-57902 |
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| Long noncoding RNA ANRIL promotes the invasion and metastasis of thyroid cancer cells through TGFβ/Smad signaling pathway |
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https://doi.org/10.18632/oncotarget.11087
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| 57903-57918 |
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| IRWRLDA: improved random walk with restart for lncRNAdisease association prediction |
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https://doi.org/10.18632/oncotarget.11141
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| 57919-57931 |
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| Anticancer effects of nitrogencontaining bisphosphonates on human cancer cells |
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https://doi.org/10.18632/oncotarget.10773
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| 57932-57942 |
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| Structural basis for exploring the allosteric inhibition of human kidney type glutaminase |
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https://doi.org/10.18632/oncotarget.10791
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| 57943-57954 |
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| Ligand activated progesterone receptor B drives autophagysenescence transition through a Beclin1/Bcl2 dependent mechanism in human breast cancer cells |
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https://doi.org/10.18632/oncotarget.10799
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| 57955-57969 |
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| DcR3 gene polymorphisms are associated with sporadic breast infiltrating ductal carcinoma in Northeast Chinese women |
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https://doi.org/10.18632/oncotarget.11153
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| 57970-57977 |
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| Increased expression of EHF contributes to thyroid tumorigenesis through transcriptionally regulating HER2 and HER3 |
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https://doi.org/10.18632/oncotarget.11154
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| 57978-57990 |
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| Prognostic value of long noncoding RNA UCA1 in human solid tumors |
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https://doi.org/10.18632/oncotarget.11155
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| 57991-58000 |
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| KRAS mutation as a prognostic factor in ampullary adenocarcinoma: a metaanalysis and review |
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https://doi.org/10.18632/oncotarget.11156
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| 58001-58006 |
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| Therapeutic implication of HER2 in advanced biliary tract cancer |
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https://doi.org/10.18632/oncotarget.11157
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| 58007-58021 |
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| Coexpression analysis identifies long noncoding RNA SNHG1 as a novel predictor for eventfree survival in neuroblastoma |
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https://doi.org/10.18632/oncotarget.11158
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| 58022-58037 |
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| Ethacrynic acid improves the antitumor effects of irreversible epidermal growth factor receptor tyrosine kinase inhibitors in breast cancer |
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https://doi.org/10.18632/oncotarget.10846
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| 58038-58050 |
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| ABCB1 as predominant resistance mechanism in cells with acquired SNS032 resistance |
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https://doi.org/10.18632/oncotarget.11160
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| 58051-58064 |
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| Impaired mitophagy in Fanconi anemia is dependent on mitochondrial fission |
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https://doi.org/10.18632/oncotarget.11161
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| 58065-58074 |
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| Simultaneous activation and inhibition of autophagy sensitizes cancer cells to chemotherapy |
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https://doi.org/10.18632/oncotarget.10873
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| 58075-58088 |
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| Preconditioning of bone marrow mesenchymal stem cells with hydrogen sulfide improves their therapeutic potential |
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https://doi.org/10.18632/oncotarget.11166
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| 58089-58104 |
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| Comparison of the EORTC criteria and PERCIST in solid tumors: a pooled analysis and review |
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https://doi.org/10.18632/oncotarget.11171
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| 58105-58110 |
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| Suppression of breast cancer metastasis through the inactivation of ADPribosylation factor 1 |
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https://doi.org/10.18632/oncotarget.11185
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| 58111-58120 |
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| Radiofrequency plasma polymerized biodegradable carrier for in vivo release of cisplatinum |
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https://doi.org/10.18632/oncotarget.10932
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| 58121-58132 |
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| CombretastatinA4 phosphate improves the distribution and antitumor efficacy of albuminbound paclitaxel in W256 breast carcinoma model |
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https://doi.org/10.18632/oncotarget.11249
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| 58133-58141 |
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| Bromodomain inhibitor OTX015 MK8628 combined with targeted agents shows strong in vivo antitumor activity in lymphoma |
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https://doi.org/10.18632/oncotarget.10983
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| 58142-58147 |
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| miR4975p inhibits cell proliferation and invasion by targeting KCa31 in angiosarcoma |
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https://doi.org/10.18632/oncotarget.11252
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| 58148-58161 |
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| Matriptase regulates cMet mediated proliferation and invasion in inflammatory breast cancer |
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https://doi.org/10.18632/oncotarget.11262
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| 58162-58173 |
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| Impacts of the mTOR gene polymorphisms rs2536 and rs2295080 on breast cancer risk in the Chinese population |
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https://doi.org/10.18632/oncotarget.11272
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| 58174-58180 |
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| IL1α and IL1βproducing macrophages populate lung tumor lesions in mice |
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https://doi.org/10.18632/oncotarget.11276
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| 58181-58192 |
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| UBE2C cellfree RNA in urine can discriminate between bladder cancer and hematuria |
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https://doi.org/10.18632/oncotarget.11277
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| 58193-58202 |
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| The putative tumor suppressor gene EphA7 is a novel BMI1 target |
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https://doi.org/10.18632/oncotarget.11279
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| 58203-58217 |
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| MicroRNA 7443p promotes MMP9mediated metastasis by simultaneously suppressing PDCD4 and PTEN in laryngeal squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.11280
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| 58218-58233 |
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| A clinical observation of Chinese chronic myelogenous leukemia patients after discontinuation of tyrosine kinase inhibitors |
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https://doi.org/10.18632/oncotarget.11281
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| 58234-58243 |
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| Proteolysisa characteristic of tumorinitiating cells in murine metastatic breast cancer |
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https://doi.org/10.18632/oncotarget.11309
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| 58244-58260 |
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| Factors predicting organspecific distant metastasis in patients with completely resected lung adenocarcinoma |
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https://doi.org/10.18632/oncotarget.11338
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| 58261-58273 |
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| C23 promotes tumorigenesis via suppressing p53 activity |
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https://doi.org/10.18632/oncotarget.11071
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| 58274-58285 |
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| Aberrant DR5 transport through disruption of lysosomal function suggests a novel mechanism for receptor activation |
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https://doi.org/10.18632/oncotarget.11073
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| 58286-58301 |
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| Prognostic nomogram for postsurgical treatment with adjuvant TACE in hepatitis B virusrelated hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.11078
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| 58302-58314 |
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| Gproteincoupled receptors mediate ω3 PUFAsinhibited colorectal cancer by activating the Hippo pathway |
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https://doi.org/10.18632/oncotarget.11089
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| 58315-58330 |
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| Targeting antisense mitochondrial ncRNAs inhibits murine melanoma tumor growth and metastasis through reduction in survival and invasion factors |
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https://doi.org/10.18632/oncotarget.11110
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| 58331-58350 |
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| CD44 and CD24 coordinate the reprogramming of nasopharyngeal carcinoma cells towards a cancer stem cell phenotype through STAT3 activation |
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https://doi.org/10.18632/oncotarget.11113
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| 58351-58366 |
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| Upregulation of microRNA let7c by quercetin inhibits pancreatic cancer progression by activation of Numbl |
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https://doi.org/10.18632/oncotarget.11122
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| 58367-58380 |
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| Growth factor progranulin promotes tumorigenesis of cervical cancer via PI3K/Akt/mTOR signaling pathway |
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https://doi.org/10.18632/oncotarget.11126
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| 58381-58395 |
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| The DDGP cisplatin dexamethasone gemcitabine and pegaspargase regimen for treatment of extranodal natural killer NK/Tcell lymphoma nasal type |
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https://doi.org/10.18632/oncotarget.11135
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| 58396-58404 |
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| The tripeptide GHKCu complex ameliorates lipopolysaccharideinduced acute lung injury in mice |
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https://doi.org/10.18632/oncotarget.11168
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| 58405-58417 |
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| A recombinantly tailored βdefensin that displays intensive macropinocytosismediated uptake exerting potent efficacy against KRas mutant pancreatic cancer |
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https://doi.org/10.18632/oncotarget.11170
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| 58418-58434 |
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| TP53 mutated glioblastoma stemlike cell cultures are sensitive to dual mTORC1/2 inhibition while resistance in TP53 wild type cultures can be overcome by combined inhibition of mTORC1/2 and Bcl2 |
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https://doi.org/10.18632/oncotarget.11205
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| 58435-58444 |
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| Doxorubicintriggered selfassembly of native amphiphilic peptides into spherical nanoparticles |
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https://doi.org/10.18632/oncotarget.11213
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| 58445-58458 |
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| Prognostic values of normal preoperative serum cancer markers for gastric cancer |
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https://doi.org/10.18632/oncotarget.11248
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| 58459-58469 |
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| Elevated eukaryotic elongation factor 2 expression is involved in proliferation and invasion of lung squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.11298
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| 58470-58482 |
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| DCUN1D3 activates SCFSKP2 ubiquitin E3 ligase activity and cell cycle progression under UV damage |
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https://doi.org/10.18632/oncotarget.11302
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| 58483-58491 |
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| Detection of the T790M mutation of EGFR in plasma of advanced non–small cell lung cancer patients with acquired resistance to tyrosine kinase inhibitors West Japan oncology group 8014LTR study |
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https://doi.org/10.18632/oncotarget.11303
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| 58492-58499 |
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| The reliable assurance of detecting somatic mutations in cancerrelated genes by nextgeneration sequencing: the results of external quality assessment in China |
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https://doi.org/10.18632/oncotarget.11306
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| 58500-58515 |
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| Targeting ALDH1A1 by disulfiram/copper complex inhibits nonsmall cell lung cancer recurrence driven by ALDHpositive cancer stem cells |
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https://doi.org/10.18632/oncotarget.11305
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| 58516-58530 |
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| Targeting a novel cancerdriving protein LAPTM4B35 by a small molecule ETS to inhibit cancer growth and metastasis |
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https://doi.org/10.18632/oncotarget.11325
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| 58531-58542 |
Clinical Research Papers
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| Prognostic significance of preoperative prognostic nutritional index in colorectal cancer: results from a retrospective cohort study and a metaanalysis |
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https://doi.org/10.18632/oncotarget.10148
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| 58543-58552 |
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| Randomized clinical trial: Nucleostide analogues improved survival of CHBrelated HCC patients via reducing severity and progression of malignancy |
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https://doi.org/10.18632/oncotarget.10155
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| 58553-58562 |
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| Nuclear localization of B7H4 in pulmonary adenocarcinomas presenting as a solitary pulmonary nodule |
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https://doi.org/10.18632/oncotarget.10542
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| 58563-58568 |
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| Clinical utility of microRNA378 as early diagnostic biomarker of human cancers: a metaanalysis of diagnostic test |
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https://doi.org/10.18632/oncotarget.10707
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| 58569-58578 |
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| Oxaliplatin 5fluorouracil and leucovorin FOLFOX as secondline therapy for patients with advanced urothelial cancer |
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https://doi.org/10.18632/oncotarget.10463
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| 58579-58585 |
Reviews
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| Clonal evolution of acute myeloid leukemia highlighted by latest genome sequencing studies |
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https://doi.org/10.18632/oncotarget.10850
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| 58586-58594 |
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| AntimiR203 suppresses ERpositive breast cancer growth and stemness by targeting SOCS3 |
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https://doi.org/10.18632/oncotarget.11193
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| 58595-58605 |
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| Diagnostic value of microRNAs in asbestos exposure and malignant mesothelioma: systematic review and qualitative metaanalysis |
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https://doi.org/10.18632/oncotarget.9686
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| 58606-58637 |
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| Gene mutations and actionable genetic lesions in mantle cell lymphoma |
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https://doi.org/10.18632/oncotarget.10716
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| 58638-58648 |
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| Angiogenesis in pancreatic ductal adenocarcinoma: A controversial issue |
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https://doi.org/10.18632/oncotarget.10765
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| 58649-58658 |
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| An updated metaanalysis of 37 casecontrol studies on the association between NFKB1 94ins/del ATTG promoter polymorphism and cancer susceptibility |
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https://doi.org/10.18632/oncotarget.10808
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| 58659-58670 |
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| Decellularized scaffolds in regenerative medicine |
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https://doi.org/10.18632/oncotarget.10945
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| 58671-58683 |
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| Advanced new strategies for metastatic cancer treatment by therapeutic stem cells and oncolytic virotherapy |
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https://doi.org/10.18632/oncotarget.11017
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| 58684-58695 |
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| Cancer diagnostics: The journey from histomorphology to molecular profiling |
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https://doi.org/10.18632/oncotarget.11061
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| 58696-58708 |
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| Weekly versus three weeks chemotherapy for advanced ovarian cancer: a metaanalysis |
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https://doi.org/10.18632/oncotarget.11094
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| 58709-58715 |
Corrections
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| Correction: Mutation of the BRCA1 SQcluster results in aberrant mitosis reduced homologous recombination and a compensatory increase in nonhomologous end joining |
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https://doi.org/10.18632/oncotarget.11846
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| 58716 |
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Oncotarget ® is a registered trademark of Rapamycin Press LLC
Impact Journals ® is a registered trademark of Rapamycin Press LLC
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