Priority Research Papers
|
| BRCA somatic and germline mutation detection in paraffin embedded ovarian cancers by nextgeneration sequencing |
|
https://doi.org/10.18632/oncotarget.6834
|
| 1076-1083 |
Research Papers: Gerotarget (Focus on Aging)
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| Kupffer cellsdependent inflammation in the injured liver increases recruitment of mesenchymal stem cells in aging mice |
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https://doi.org/10.18632/oncotarget.6744
|
| 1084-1095 |
Research Papers: Pathology
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| Microbiota and bile acid profiles in retinoic acidprimed mice that exhibit accelerated liver regeneration |
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https://doi.org/10.18632/oncotarget.6665
|
| 1096-1106 |
|
| Altered expression of epithelialtomesenchymal transition proteins in extraprostatic prostate cancer |
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https://doi.org/10.18632/oncotarget.6689
|
| 1107-1119 |
|
| The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signaling |
|
https://doi.org/10.18632/oncotarget.6683
|
| 1120-1143 |
|
| Assessing sirtuin expression in endometrial carcinoma and nonneoplastic endometrium |
|
https://doi.org/10.18632/oncotarget.6691
|
| 1144-1154 |
|
| Mitoguardin1 and 2 promote maturation and the developmental potential of mouse oocytes by maintaining mitochondrial dynamics and functions |
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https://doi.org/10.18632/oncotarget.6713
|
| 1155-1167 |
Research Papers: Immunology
|
| Activated T cells sustain myeloidderived suppressor cellmediated immune suppression |
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https://doi.org/10.18632/oncotarget.6662
|
| 1168-1184 |
|
| Ineffectiveness of the 20142015 H3N2 influenza vaccine |
|
https://doi.org/10.18632/oncotarget.6746
|
| 1185-1192 |
Reviews
|
| Can active components of licorice glycyrrhizin and glycyrrhetinic acid lick rheumatoid arthritis |
|
https://doi.org/10.18632/oncotarget.6200
|
| 1193-1202 |
|
| CCN: core regulatory proteins in the microenvironment that affect the metastasis of hepatocellular carcinoma |
|
https://doi.org/10.18632/oncotarget.6209
|
| 1203-1214 |
|
| Tumorsphere as an effective in vitro platform for screening anticancer stem cell drugs |
|
https://doi.org/10.18632/oncotarget.6261
|
| 1215-1226 |
Research Papers
|
| Fisetin a dietary flavonoid augments the antiinvasive and antimetastatic potential of sorafenib in melanoma |
|
https://doi.org/10.18632/oncotarget.6237
|
| 1227-1241 |
|
| Novel p53dependent anticancer strategy by targeting iron signaling and BNIP3Linduced mitophagy |
|
https://doi.org/10.18632/oncotarget.6233
|
| 1242-1261 |
|
| Leptin as a mediator of tumorstromal interactions promotes breast cancer stem cell activity |
|
https://doi.org/10.18632/oncotarget.6014
|
| 1262-1275 |
|
| MicroRNA152mediated dysregulation of hepatic transferrin receptor 1 in liver carcinogenesis |
|
https://doi.org/10.18632/oncotarget.6004
|
| 1276-1287 |
|
| MiR630 suppresses breast cancer progression by targeting metadherin |
|
https://doi.org/10.18632/oncotarget.6339
|
| 1288-1299 |
|
| A PCA3 genebased transcriptional amplification system targeting primary prostate cancer |
|
https://doi.org/10.18632/oncotarget.6360
|
| 1300-1310 |
|
| NDRG4 stratifies the prognostic value of body mass index in colorectal cancer |
|
https://doi.org/10.18632/oncotarget.6182
|
| 1311-1322 |
|
| Synergistic cytotoxic effects of bortezomib and CK2 inhibitor CX4945 in acute lymphoblastic leukemia: turning off the prosurvival ER chaperone BIP/Grp78 and turning on the proapoptotic NFκB |
|
https://doi.org/10.18632/oncotarget.6361
|
| 1323-1340 |
|
| Infiltrating mast cells increase prostate cancer chemotherapy and radiotherapy resistances via modulation of p38/p53/p21 and ATM signals |
|
https://doi.org/10.18632/oncotarget.6372
|
| 1341-1353 |
|
| Diverse in vivo effects of soluble and membranebound MCSF on tumorassociated macrophages in lymphoma xenograft model |
|
https://doi.org/10.18632/oncotarget.6362
|
| 1354-1366 |
|
| KIT overexpression by p55PIKPI3K leads to Imatinibresistance in patients with gastrointestinal stromal tumors |
|
https://doi.org/10.18632/oncotarget.6011
|
| 1367-1379 |
|
| A subset of cancer cell lines is acutely sensitive to the Chk1 inhibitor MK8776 as monotherapy due to CDK2 activation in S phase |
|
https://doi.org/10.18632/oncotarget.6364
|
| 1380-1394 |
|
| Targeting PDK1 with dichloroacetophenone to inhibit acute myeloid leukemia AML cell growth |
|
https://doi.org/10.18632/oncotarget.6366
|
| 1395-1407 |
|
| Epigenetic repression of PDZLIM domaincontaining protein 2 promotes ovarian cancer via NOS2derived nitric oxide signaling |
|
https://doi.org/10.18632/oncotarget.6368
|
| 1408-1420 |
|
| Integration of tissue metabolomics transcriptomics and immunohistochemistry reveals ERG and gleason scorespecific metabolomic alterations in prostate cancer |
|
https://doi.org/10.18632/oncotarget.6370
|
| 1421-1438 |
|
| ERK8 is a novel HuR kinase that regulates tumour suppressor PDCD4 through a miR21 dependent mechanism |
|
https://doi.org/10.18632/oncotarget.6363
|
| 1439-1450 |
|
| Targeting the EWSETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma |
|
https://doi.org/10.18632/oncotarget.6385
|
| 1451-1463 |
|
| Doublecortinlike kinase 1 expression associates with breast cancer with neuroendocrine differentiation |
|
https://doi.org/10.18632/oncotarget.6386
|
| 1464-1476 |
|
| Negative correlation of ITCH E3 ubiquitin ligase and miRNA106b dictates metastatic progression in pancreatic cancer |
|
https://doi.org/10.18632/oncotarget.6395
|
| 1477-1485 |
|
| Prognostic impact of programmed cell death1 PD1 and PDligand 1 PDL1 expression in cancer cells and tumorinfiltrating lymphocytes in ovarian high grade serous carcinoma |
|
https://doi.org/10.18632/oncotarget.6429
|
| 1486-1499 |
|
| The oncolytic virus dl922947 reduces IL8/CXCL8 and MCP1/CCL2 expression and impairs angiogenesis and macrophage infiltration in anaplastic thyroid carcinoma |
|
https://doi.org/10.18632/oncotarget.6430
|
| 1500-1515 |
|
| The antitumor NC1 domain of collagen XIX inhibits the FAK/ PI3K/Akt/mTOR signaling pathway through αvβ3 integrin interaction |
|
https://doi.org/10.18632/oncotarget.6399
|
| 1516-1528 |
|
| Critical role of PPARγ in myeloidderived suppressor cellstimulated cancer cell proliferation and metastasis |
|
https://doi.org/10.18632/oncotarget.6414
|
| 1529-1543 |
|
| Zerumbone suppresses the motility and tumorigenecity of triple negative breast cancer cells via the inhibition of TGFβ1 signaling pathway |
|
https://doi.org/10.18632/oncotarget.6441
|
| 1544-1558 |
|
| microRNA20a in human faeces as a noninvasive biomarker for colorectal cancer |
|
https://doi.org/10.18632/oncotarget.6403
|
| 1559-1568 |
|
| The pepper’s natural ingredient capsaicin induces autophagy blockage in prostate cancer cells |
|
https://doi.org/10.18632/oncotarget.6415
|
| 1569-1583 |
|
| miR382 targeting PTENAkt axis promotes liver regeneration |
|
https://doi.org/10.18632/oncotarget.6444
|
| 1584-1597 |
|
| Targeting heparanase overcomes chemoresistance and diminishes relapse in myeloma |
|
https://doi.org/10.18632/oncotarget.6408
|
| 1598-1607 |
|
| ROR functions as a ceRNA to regulate Nanog expression by sponging miR145 and predicts poor prognosis in pancreatic cancer |
|
https://doi.org/10.18632/oncotarget.6450
|
| 1608-1618 |
|
| Ginsenoside Rg3 inhibits epithelialmesenchymal transition EMT and invasion of lung cancer by downregulating FUT4 |
|
https://doi.org/10.18632/oncotarget.6451
|
| 1619-1632 |
|
| NFY activates genes of metabolic pathways altered in cancer cells |
|
https://doi.org/10.18632/oncotarget.6453
|
| 1633-1650 |
|
| Therapeutic effect of TMZPOH on human nasopharyngeal carcinoma depends on reactive oxygen species accumulation |
|
https://doi.org/10.18632/oncotarget.6410
|
| 1651-1662 |
|
| The matricellular protein CYR61 interferes with normal pancreatic islets architecture and promotes pancreatic neuroendocrine tumor progression |
|
https://doi.org/10.18632/oncotarget.6411
|
| 1663-1674 |
|
| Apoptosis induced by a HIPK2 fulllengthspecific siRNA is due to offtarget effects rather than prevalence of HIPK2Δe8 isoform |
|
https://doi.org/10.18632/oncotarget.6423
|
| 1675-1686 |
|
| Human Tcell leukemia virus type1encoded protein HBZ represses p53 function by inhibiting the acetyltransferase activity of p300/CBP and HBO1 |
|
https://doi.org/10.18632/oncotarget.6424
|
| 1687-1706 |
|
| Multiplatform molecular profiling identifies potentially targetable biomarkers in malignant phyllodes tumors of the breast |
|
https://doi.org/10.18632/oncotarget.6421
|
| 1707-1716 |
|
| Dimeric peroxiredoxins are druggable targets in human Burkitt lymphoma |
|
https://doi.org/10.18632/oncotarget.6435
|
| 1717-1731 |
|
| Molecular analyses reveal close similarities between small cell carcinoma of the ovary hypercalcemic type and atypical teratoid/rhabdoid tumor |
|
https://doi.org/10.18632/oncotarget.6459
|
| 1732-1740 |
|
| Epigenetic regulation of ZEB1RAB25/ESRP1 axis plays a critical role in phenylbutyrate treatmentresistant breast cancer |
|
https://doi.org/10.18632/oncotarget.6480
|
| 1741-1753 |
|
| Protein phosphatase 1 suppresses androgen receptor ubiquitylation and degradation |
|
https://doi.org/10.18632/oncotarget.6434
|
| 1754-1764 |
|
| Reducing the serine availability complements the inhibition of the glutamine metabolism to block leukemia cell growth |
|
https://doi.org/10.18632/oncotarget.6426
|
| 1765-1776 |
|
| Targeting oncogenic PLCE1 by miR145 impairs tumor proliferation and metastasis of esophageal squamous cell carcinoma |
|
https://doi.org/10.18632/oncotarget.6499
|
| 1777-1795 |
|
| Nonepigenetic function of HDAC8 in regulating breast cancer stem cells by maintaining Notch1 protein stability |
|
https://doi.org/10.18632/oncotarget.6427
|
| 1796-1807 |
|
| MICAL2 is a novel human cancer gene controlling mesenchymal to epithelial transition involved in cancer growth and invasion |
|
https://doi.org/10.18632/oncotarget.6577
|
| 1808-1825 |
|
| Griffipavixanthone a dimeric xanthone extracted from edible plants inhibits tumor metastasis and proliferation via downregulation of the RAF pathway in esophageal cancer |
|
https://doi.org/10.18632/oncotarget.6484
|
| 1826-1837 |
|
| A versatile ex vivo technique for assaying tumor angiogenesis and microglia in the brain |
|
https://doi.org/10.18632/oncotarget.6550
|
| 1838-1853 |
|
| Serum cyclindependent kinase 9 is a potential biomarker of atherosclerotic inflammation |
|
https://doi.org/10.18632/oncotarget.6443
|
| 1854-1862 |
|
| A method for quantification of exportin1 XPO1 occupancy by Selective Inhibitor of Nuclear Export SINE compounds |
|
https://doi.org/10.18632/oncotarget.6495
|
| 1863-1877 |
|
| Low β2adrenergic receptor level may promote development of castration resistant prostate cancer and altered steroid metabolism |
|
https://doi.org/10.18632/oncotarget.6479
|
| 1878-1894 |
|
| Genomewide identification of Wig1 mRNA targets by RIPSeq analysis |
|
https://doi.org/10.18632/oncotarget.6557
|
| 1895-1911 |
|
| Forkhead transcription factor FoxF1 interacts with Fanconi anemia protein complexes to promote DNA damage response |
|
https://doi.org/10.18632/oncotarget.6422
|
| 1912-1926 |
|
| Dynamic reprogramming of DNA methylation in SETD2deregulated renal cell carcinoma |
|
https://doi.org/10.18632/oncotarget.6481
|
| 1927-1946 |
|
| ATRChk1 signaling inhibition as a therapeutic strategy to enhance cisplatin chemosensitivity in urothelial bladder cancer |
|
https://doi.org/10.18632/oncotarget.6482
|
| 1947-1959 |
|
| MethylCpGbinding domain sequencing reveals a prognostic methylation signature in neuroblastoma |
|
https://doi.org/10.18632/oncotarget.6477
|
| 1960-1972 |
|
| Extensive regulation of nicotinate phosphoribosyltransferase NAPRT expression in human tissues and tumors |
|
https://doi.org/10.18632/oncotarget.6538
|
| 1973-1983 |
|
| Autophagy induction causes a synthetic lethal sensitization to ribonucleotide reductase inhibition in breast cancer cells |
|
https://doi.org/10.18632/oncotarget.6539
|
| 1984-1999 |
|
| Metformin may reduce oral cancer risk in patients with type 2 diabetes |
|
https://doi.org/10.18632/oncotarget.6626
|
| 2000-2008 |
|
| Connexin 32 dysfunction promotes ethanolrelated hepatocarcinogenesis via activation of Dusp1Erk axis |
|
https://doi.org/10.18632/oncotarget.6511
|
| 2009-2021 |
|
| MULTIMERIN2 binds VEGFA primarily via the carbohydrate chains exerting an angiostatic function and impairing tumor growth |
|
https://doi.org/10.18632/oncotarget.6515
|
| 2022-2037 |
|
| Loss of 11βHSD1 enhances glycolysis facilitates intrahepatic metastasis and indicates poor prognosis in hepatocellular carcinoma |
|
https://doi.org/10.18632/oncotarget.6661
|
| 2038-2053 |
|
| Human βdefensin 3 contains an oncolytic motif that binds PI45P2 to mediate tumour cell permeabilisation |
|
https://doi.org/10.18632/oncotarget.6520
|
| 2054-2069 |
|
| Enhancement of antileukemia activity of NK cells in vitro and in vivo by inhibition of leukemia cellinduced NK cell damage |
|
https://doi.org/10.18632/oncotarget.6529
|
| 2070-2079 |
|
| The ATF6 pathway of the ER stress response contributes to enhanced viability in glioblastoma |
|
https://doi.org/10.18632/oncotarget.6712
|
| 2080-2092 |
|
| AEG1 activates Wnt/PCP signaling to promote metastasis in tongue squamous cell carcinoma |
|
https://doi.org/10.18632/oncotarget.6573
|
| 2093-2104 |
Clinical Research Papers
|
| The androgen receptor cytosineadenineguanine repeat length contributes to the development of epithelial ovarian cancer |
|
https://doi.org/10.18632/oncotarget.6012
|
| 2105-2112 |
|
| Mutant GDF15 presents a poor prognostic outcome for patients with oral squamous cell carcinoma |
|
https://doi.org/10.18632/oncotarget.6017
|
| 2113-2122 |
|
| A prognostic classifier for patients with colorectal cancer liver metastasis based on AURKA PTGS2 and MMP9 |
|
https://doi.org/10.18632/oncotarget.6188
|
| 2123-2134 |
|
| Prognostic impact of EpsteinBarr virus EBVDNA copy number at diagnosis in chronic lymphocytic leukemia |
|
https://doi.org/10.18632/oncotarget.6281
|
| 2135-2142 |
|
| Relationship of Oct4 to malignant stage: a metaanalysis based on 502 positive/high Oct4 cases and 522 negative/low casefree controls |
|
https://doi.org/10.18632/oncotarget.5737
|
| 2143-2152 |
Errata
|
| Erratum: PBK/TOPK enhances aggressive phenotype in prostate cancer via βcateninTCF/LEFmediated matrix metalloproteinases production and invasion |
|
https://doi.org/10.18632/oncotarget.6865
|
| 2153-2154 |
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