Vol 7, No 2

Altered expression of epithelial-to-mesenchymal transition proteins in extraprostatic prostate cancer

The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signaling

Assessing sirtuin expression in endometrial carcinoma and non-neoplastic endometrium

Mitoguardin-1 and -2 promote maturation and the developmental potential of mouse oocytes by maintaining mitochondrial dynamics and functions

Ineffectiveness of the 2014-2015 H3N2 influenza vaccine

CCN: core regulatory proteins in the microenvironment that affect the metastasis of hepatocellular carcinoma?

Tumorsphere as an effective in vitro platform for screening anti-cancer stem cell drugs

Novel p53-dependent anticancer strategy by targeting iron signaling and BNIP3L-induced mitophagy

Leptin as a mediator of tumor-stromal interactions promotes breast cancer stem cell activity

MicroRNA-152-mediated dysregulation of hepatic transferrin receptor 1 in liver carcinogenesis

MiR-630 suppresses breast cancer progression by targeting metadherin

A PCA3 gene-based transcriptional amplification system targeting primary prostate cancer

NDRG4 stratifies the prognostic value of body mass index in colorectal cancer

Synergistic cytotoxic effects of bortezomib and CK2 inhibitor CX-4945 in acute lymphoblastic leukemia: turning off the prosurvival ER chaperone BIP/Grp78 and turning on the pro-apoptotic NF-κB

Infiltrating mast cells increase prostate cancer chemotherapy and radiotherapy resistances via modulation of p38/p53/p21 and ATM signals

Diverse in vivo effects of soluble and membrane-bound M-CSF on tumor-associated macrophages in lymphoma xenograft model

KIT over-expression by p55PIK-PI3K leads to Imatinib-resistance in patients with gastrointestinal stromal tumors

A subset of cancer cell lines is acutely sensitive to the Chk1 inhibitor MK-8776 as monotherapy due to CDK2 activation in S phase

Targeting PDK1 with dichloroacetophenone to inhibit acute myeloid leukemia (AML) cell growth

Epigenetic repression of PDZ-LIM domain-containing protein 2 promotes ovarian cancer via NOS2-derived nitric oxide signaling

Integration of tissue metabolomics, transcriptomics and immunohistochemistry reveals ERG- and gleason score-specific metabolomic alterations in prostate cancer

ERK8 is a novel HuR kinase that regulates tumour suppressor PDCD4 through a miR-21 dependent mechanism

Targeting the EWS-ETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma

Doublecortin-like kinase 1 expression associates with breast cancer with neuroendocrine differentiation

Negative correlation of ITCH E3 ubiquitin ligase and miRNA-106b dictates metastatic progression in pancreatic cancer

Prognostic impact of programmed cell death-1 (PD-1) and PD-ligand 1 (PD-L1) expression in cancer cells and tumor-infiltrating lymphocytes in ovarian high grade serous carcinoma

The oncolytic virus dl922-947 reduces IL-8/CXCL8 and MCP-1/CCL2 expression and impairs angiogenesis and macrophage infiltration in anaplastic thyroid carcinoma

The anti-tumor NC1 domain of collagen XIX inhibits the FAK/ PI3K/Akt/mTOR signaling pathway through αvβ3 integrin interaction

Critical role of PPARγ in myeloid-derived suppressor cell-stimulated cancer cell proliferation and metastasis

Zerumbone suppresses the motility and tumorigenecity of triple negative breast cancer cells via the inhibition of TGF-β1 signaling pathway

microRNA-20a in human faeces as a non-invasive biomarker for colorectal cancer

The pepper’s natural ingredient capsaicin induces autophagy blockage in prostate cancer cells

miR-382 targeting PTEN-Akt axis promotes liver regeneration

Targeting heparanase overcomes chemoresistance and diminishes relapse in myeloma

ROR functions as a ceRNA to regulate Nanog expression by sponging miR-145 and predicts poor prognosis in pancreatic cancer

Ginsenoside Rg3 inhibits epithelial-mesenchymal transition (EMT) and invasion of lung cancer by down-regulating FUT4

NF-Y activates genes of metabolic pathways altered in cancer cells

Therapeutic effect of TMZ-POH on human nasopharyngeal carcinoma depends on reactive oxygen species accumulation

The matricellular protein CYR61 interferes with normal pancreatic islets architecture and promotes pancreatic neuroendocrine tumor progression

Apoptosis induced by a HIPK2 full-length-specific siRNA is due to off-target effects rather than prevalence of HIPK2-Δe8 isoform

Human T-cell leukemia virus type-1-encoded protein HBZ represses p53 function by inhibiting the acetyltransferase activity of p300/CBP and HBO1

Multiplatform molecular profiling identifies potentially targetable biomarkers in malignant phyllodes tumors of the breast

Dimeric peroxiredoxins are druggable targets in human Burkitt lymphoma

Molecular analyses reveal close similarities between small cell carcinoma of the ovary, hypercalcemic type and atypical teratoid/rhabdoid tumor

Epigenetic regulation of ZEB1-RAB25/ESRP1 axis plays a critical role in phenylbutyrate treatment-resistant breast cancer

Protein phosphatase 1 suppresses androgen receptor ubiquitylation and degradation

Reducing the serine availability complements the inhibition of the glutamine metabolism to block leukemia cell growth

Targeting oncogenic PLCE1 by miR-145 impairs tumor proliferation and metastasis of esophageal squamous cell carcinoma

Non-epigenetic function of HDAC8 in regulating breast cancer stem cells by maintaining Notch1 protein stability

MICAL2 is a novel human cancer gene controlling mesenchymal to epithelial transition involved in cancer growth and invasion

Griffipavixanthone, a dimeric xanthone extracted from edible plants, inhibits tumor metastasis and proliferation via downregulation of the RAF pathway in esophageal cancer

A versatile ex vivo technique for assaying tumor angiogenesis and microglia in the brain

Serum cyclin-dependent kinase 9 is a potential biomarker of atherosclerotic inflammation

A method for quantification of exportin-1 (XPO1) occupancy by Selective Inhibitor of Nuclear Export (SINE) compounds

Low β₂-adrenergic receptor level may promote development of castration resistant prostate cancer and altered steroid metabolism

Genome-wide identification of Wig-1 mRNA targets by RIP-Seq analysis

Forkhead transcription factor FoxF1 interacts with Fanconi anemia protein complexes to promote DNA damage response

Dynamic reprogramming of DNA methylation in SETD2-deregulated renal cell carcinoma

ATR-Chk1 signaling inhibition as a therapeutic strategy to enhance cisplatin chemosensitivity in urothelial bladder cancer

Methyl-CpG-binding domain sequencing reveals a prognostic methylation signature in neuroblastoma

Extensive regulation of nicotinate phosphoribosyltransferase (NAPRT) expression in human tissues and tumors

Autophagy induction causes a synthetic lethal sensitization to ribonucleotide reductase inhibition in breast cancer cells

Metformin may reduce oral cancer risk in patients with type 2 diabetes

Connexin 32 dysfunction promotes ethanol-related hepatocarcinogenesis via activation of Dusp1-Erk axis

MULTIMERIN2 binds VEGF-A primarily via the carbohydrate chains exerting an angiostatic function and impairing tumor growth

Loss of 11βHSD1 enhances glycolysis, facilitates intrahepatic metastasis, and indicates poor prognosis in hepatocellular carcinoma

Human β-defensin 3 contains an oncolytic motif that binds PI(4,5)P2 to mediate tumour cell permeabilisation

Enhancement of anti-leukemia activity of NK cells in vitro and in vivo by inhibition of leukemia cell-induced NK cell damage

The ATF6 pathway of the ER stress response contributes to enhanced viability in glioblastoma

AEG-1 activates Wnt/PCP signaling to promote metastasis in tongue squamous cell carcinoma

Mutant GDF15 presents a poor prognostic outcome for patients with oral squamous cell carcinoma

A prognostic classifier for patients with colorectal cancer liver metastasis, based on AURKA, PTGS2 and MMP9

Prognostic impact of Epstein-Barr virus (EBV)-DNA copy number at diagnosis in chronic lymphocytic leukemia

Relationship of Oct-4 to malignant stage: a meta-analysis based on 502 positive/high Oct-4 cases and 522 negative/low case-free controls