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C. novyi-NT induces a potent local host-inflammatory response in 060919 (G) and F98 (H, shown) bearing animal. See Staedtke et al.
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Table of Contents
Editorial
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| Mitochondria fingerprint longevity in iPSCs |
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https://doi.org/10.18632/oncotarget.3530
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| 5475-5476 |
Reviews
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| Structural variation discovery in the cancer genome using next generation sequencing: Computational solutions and perspectives |
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https://doi.org/10.18632/oncotarget.3491
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| 5477-5489 |
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| Aberrant nuclear factorkappa B activity in acute myeloid Leukemia: from molecular pathogenesis to therapeutic target |
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https://doi.org/10.18632/oncotarget.3545
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| 5490-5500 |
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| Inhibition of BET bromodomains as a therapeutic strategy for cancer drug discovery |
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https://doi.org/10.18632/oncotarget.3551
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| 5501-5516 |
Research Perspectives
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| Combination of carbon ion beam and gemcitabine causes irreparable DNA damage and death of radioresistant pancreatic cancer stemlike cells in vitro and in vivo |
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https://doi.org/10.18632/oncotarget.3584
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| 5517-5535 |
Priority Research Papers
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| Clostridium novyiNT can cause regression of orthotopically implanted glioblastomas in rats |
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https://doi.org/10.18632/oncotarget.3627
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| 5536-5546 |
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| Gain of function mutant p53 proteins cooperate with E2F4 to transcriptionally downregulate RAD17 and BRCA1 gene expression |
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https://doi.org/10.18632/oncotarget.2587
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| 5547-5566 |
Research Papers
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| miR17 inhibition enhances the formation of kidney cancer spheres with stem cell/ tumor initiating cell properties |
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https://doi.org/10.18632/oncotarget.1901
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| 5567-5581 |
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| Dihydroartemisinin and its derivative induce apoptosis in acute myeloid leukemia through Noxamediated pathway requiring iron and endoperoxide moiety |
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https://doi.org/10.18632/oncotarget.3336
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| 5582-5596 |
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| Dysregulated CXCR4 expression promotes lymphoma cell survival and independently predicts disease progression in germinal center Bcelllike diffuse large Bcell lymphoma |
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https://doi.org/10.18632/oncotarget.3343
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| 5597-5614 |
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| Clinical and biological significance of de novo CD5+ diffuse large Bcell lymphoma in Western countries |
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https://doi.org/10.18632/oncotarget.3479
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| 5615-5633 |
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| Clonal expansion and linear genome evolution through breast cancer progression from preinvasive stages to asynchronous metastasis |
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https://doi.org/10.18632/oncotarget.3111
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| 5634-5649 |
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| Knockdown of GALNT1 suppresses malignant phenotype of hepatocellular carcinoma by suppressing EGFR signaling |
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https://doi.org/10.18632/oncotarget.3117
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| 5650-5665 |
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| Pseudogene INTS6P1 regulates its cognate gene INTS6 through competitive binding of miR175p in hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.3290
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| 5666-5677 |
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| Combining lapatinib and pertuzumab to overcome lapatinib resistance due to NRG1mediated signalling in HER2amplified breast cancer |
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https://doi.org/10.18632/oncotarget.3296
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| 5678-5694 |
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| 2DDIGE proteomic analysis identifies new potential therapeutic targets for adrenocortical carcinoma |
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https://doi.org/10.18632/oncotarget.3299
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| 5695-5706 |
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| Cellspecific expression of artificial microRNAs targeting essential genes exhibit potent antitumor effect on hepatocellular carcinoma cells |
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https://doi.org/10.18632/oncotarget.3302
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| 5707-5719 |
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| NPM/ALK mutants resistant to ASP3026 display variable sensitivity to alternative ALK inhibitors but succumb to the novel compound PF06463922 |
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https://doi.org/10.18632/oncotarget.3122
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| 5720-5734 |
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| Preclinical antitumor activity of ST7612AA1: a new oral thiolbased histone deacetylase HDAC inhibitor |
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https://doi.org/10.18632/oncotarget.3240
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| 5735-5748 |
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| Myeloid differentiation primary response gene 88leukotriene B4 receptor 2 cascade mediates lipopolysaccharidepotentiated invasiveness of breast cancer cells |
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https://doi.org/10.18632/oncotarget.3304
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| 5749-5759 |
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| Somatic microsatellite variability as a predictive marker for colorectal cancer and liver cancer progression |
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https://doi.org/10.18632/oncotarget.3306
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| 5760-5771 |
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| Carboxylterminal domain of MUC16 imparts tumorigenic and metastatic functions through nuclear translocation of JAK2 to pancreatic cancer cells |
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https://doi.org/10.18632/oncotarget.3308
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| 5772-5787 |
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| EBNA3C regulates p53 through induction of Aurora kinase B |
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https://doi.org/10.18632/oncotarget.3310
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| 5788-5803 |
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| EBVLMP1 targeted DNAzyme enhances radiosensitivity by inhibiting tumor angiogenesis via the JNKs/HIF1 pathway in nasopharyngeal carcinoma |
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https://doi.org/10.18632/oncotarget.3331
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| 5804-5817 |
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| Granzyme M expressed by tumor cells promotes chemoresistance and EMT in vitro and metastasis in vivo associated with STAT3 activation |
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https://doi.org/10.18632/oncotarget.3461
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| 5818-5831 |
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| Afatinib increases sensitivity to radiation in nonsmall cell lung cancer cells with acquired EGFR T790M mutation |
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https://doi.org/10.18632/oncotarget.3332
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| 5832-5845 |
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| CD133+ ovarian cancer stemlike cells promote nonstem cancer cell metastasis via CCL5 induced epithelialmesenchymal transition |
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https://doi.org/10.18632/oncotarget.3462
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| 5846-5859 |
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| ROS generation mediates the anticancer effects of WZ35 via activating JNK and ER stress apoptotic pathways in gastric cancer |
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https://doi.org/10.18632/oncotarget.3333
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| 5860-5876 |
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| DACH1 inhibits lung adenocarcinoma invasion and tumor growth by repressing CXCL5 signaling |
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https://doi.org/10.18632/oncotarget.3463
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| 5877-5888 |
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| CRABPII and FABP5independent responsiveness of human glioblastoma cells to alltrans retinoic acid |
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https://doi.org/10.18632/oncotarget.3334
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| 5889-5902 |
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| Nuclear DICKKOPF1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer |
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https://doi.org/10.18632/oncotarget.3464
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| 5903-5917 |
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| New insights into the genetics of glioblastoma multiforme by familial exome sequencing |
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https://doi.org/10.18632/oncotarget.2950
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| 5918-5931 |
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| MiR21 promotes intrahepatic cholangiocarcinoma proliferation and growth in vitro and in vivo by targeting PTPN14 and PTEN |
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https://doi.org/10.18632/oncotarget.3465
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| 5932-5946 |
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| Discrete functions of GSK3α and GSK3β isoforms in prostate tumor growth and micrometastasis |
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https://doi.org/10.18632/oncotarget.3335
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| 5947-5962 |
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| Transforming growth factorβ pathway activity in glioblastoma |
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https://doi.org/10.18632/oncotarget.3467
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| 5963-5977 |
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| Identification of vitamin B1 metabolism as a tumorspecific radiosensitizing pathway using a highthroughput colony formation screen |
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https://doi.org/10.18632/oncotarget.3468
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| 5978-5989 |
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| The overexpression of survivin enhances the chemotherapeutic efficacy of YM155 in human hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.3337
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| 5990-6000 |
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| Circular RNA ITCH has inhibitory effect on ESCC by suppressing the Wnt/βcatenin pathway |
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https://doi.org/10.18632/oncotarget.3469
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| 6001-6013 |
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| miR1236 downregulates alphafetoprotein thus causing PTEN accumulation which inhibits the PI3K/Akt pathway and malignant phenotype in hepatoma cells |
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https://doi.org/10.18632/oncotarget.3338
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| 6014-6028 |
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| Molecular determinants of drugspecific sensitivity for epidermal growth factor receptor EGFR exon 19 and 20 mutants in nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.3472
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| 6029-6039 |
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| Initiation of esophageal squamous cell carcinoma ESCC in a murine 4nitroquinoline1oxide and alcohol carcinogenesis model |
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https://doi.org/10.18632/oncotarget.3339
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| 6040-6052 |
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| The antitumor effect is enhanced by simultaneously targeting VEGF and PROK1 in colorectal cancer |
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https://doi.org/10.18632/oncotarget.3474
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| 6053-6061 |
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| miR372 inhibits p62 in head and neck squamous cell carcinoma in vitro and in vivo |
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https://doi.org/10.18632/oncotarget.3340
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| 6062-6075 |
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| HSET overexpression fuels tumor progression via centrosome clusteringindependent mechanisms in breast cancer patients |
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https://doi.org/10.18632/oncotarget.3475
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| 6076-6091 |
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| miR1885p inhibits tumour growth and metastasis in prostate cancer by repressing LAPTM4B expression |
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https://doi.org/10.18632/oncotarget.3341
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| 6092-6104 |
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| Mechanistic rationale for MCL1 inhibition during androgen deprivation therapy |
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https://doi.org/10.18632/oncotarget.3368
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| 6105-6122 |
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| Upregulation of C1GALT1 promotes breast cancer cell growth through MUC1C signaling pathway |
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https://doi.org/10.18632/oncotarget.3045
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| 6123-6135 |
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| Hydrazinobenzoylcurcumin inhibits androgen receptor activity and growth of castrationresistant prostate cancer in mice |
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https://doi.org/10.18632/oncotarget.3346
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| 6136-6150 |
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| Gene expression profile predictive of response to chemotherapy in metastatic colorectal cancer |
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https://doi.org/10.18632/oncotarget.3152
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| 6151-6159 |
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| Elevated NIBP/TRAPPC9 mediates tumorigenesis of cancer cells through NFκB signaling |
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https://doi.org/10.18632/oncotarget.3349
|
| 6160-6178 |
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| Latephase miRNAcontrolled oncolytic adenovirus for selective killing of cancer cells |
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https://doi.org/10.18632/oncotarget.3350
|
| 6179-6190 |
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| Inhibition of Shp2 suppresses mutant EGFRinduced lung tumors in transgenic mouse model of lung adenocarcinoma |
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https://doi.org/10.18632/oncotarget.3356
|
| 6191-6202 |
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| Autophagy protects against dasatinibinduced hepatotoxicity via p38 signaling |
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https://doi.org/10.18632/oncotarget.3357
|
| 6203-6217 |
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| Targeting WISP1 to sensitize esophageal squamous cell carcinoma to irradiation |
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https://doi.org/10.18632/oncotarget.3358
|
| 6218-6234 |
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| Recurrent SKILactivating rearrangements in ETSnegative prostate cancer |
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https://doi.org/10.18632/oncotarget.3359
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| 6235-6250 |
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| ROCK inhibition promotes microtentacles that enhance reattachment of breast cancer cells |
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https://doi.org/10.18632/oncotarget.3360
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| 6251-6266 |
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| Coexpression analysis of CD133 and CD44 identifies Proneural and Mesenchymal subtypes of glioblastoma multiforme |
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https://doi.org/10.18632/oncotarget.3365
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| 6267-6280 |
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| Function of phosphorylation of NFkB p65 ser536 in prostate cancer oncogenesis |
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https://doi.org/10.18632/oncotarget.3366
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| 6281-6294 |
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| Targeting argininosuccinate synthetase negative melanomas using combination of arginine degrading enzyme and cisplatin |
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https://doi.org/10.18632/oncotarget.3370
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| 6295-6309 |
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| FBXW7 suppresses epithelialmesenchymal transition stemness and metastatic potential of cholangiocarcinoma cells |
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https://doi.org/10.18632/oncotarget.3355
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| 6310-6325 |
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| Flubendazole FDAapproved anthelmintic targets breast cancer stemlike cells |
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https://doi.org/10.18632/oncotarget.3436
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| 6326-6340 |
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| Cyclooxygenase2 blockade can improve efficacy of VEGFtargeting drugs |
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https://doi.org/10.18632/oncotarget.3437
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| 6341-6358 |
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| MicroRNA3127 promotes cell proliferation and tumorigenicity in hepatocellular carcinoma by disrupting of PI3K/AKT negative regulation |
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https://doi.org/10.18632/oncotarget.3438
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| 6359-6372 |
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| Fatty acid binding protein 5 promotes metastatic potential of triple negative breast cancer cells through enhancing epidermal growth factor receptor stability |
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https://doi.org/10.18632/oncotarget.3442
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| 6373-6385 |
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| Brassinin inhibits STAT3 signaling pathway through modulation of PIAS3 and SOCS3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel |
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https://doi.org/10.18632/oncotarget.3443
|
| 6386-6405 |
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| Piperlongumine selectively kills hepatocellular carcinoma cells and preferentially inhibits their invasion via ROSERMAPKsCHOP |
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https://doi.org/10.18632/oncotarget.3444
|
| 6406-6421 |
Clinical Research Papers
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| Variants in CDA and ABCB1 are predictors of capecitabinerelated adverse reactions in colorectal cancer |
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https://doi.org/10.18632/oncotarget.3289
|
| 6422-6430 |
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| Drug metabolism and clearance system in tumor cells of patients with multiple myeloma |
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https://doi.org/10.18632/oncotarget.3237
|
| 6431-6447 |
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| Efficacy and safety of decitabine in combination with GCSF lowdose cytarabine and aclarubicin in newly diagnosed elderly patients with acute myeloid leukemia |
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https://doi.org/10.18632/oncotarget.3361
|
| 6448-6458 |
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| Antibody response to BK polyomavirus as a prognostic biomarker and potential therapeutic target in prostate cancer |
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https://doi.org/10.18632/oncotarget.3363
|
| 6459-6469 |
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