Vol 6, No 13

iPSC-MSCs and islet allograft tolerance

Mutations of c-Cbl in myeloid malignancies

EMT, CTCs and CSCs in tumor relapse and drug-resistance

Chemotherapy induces the cancer-associated fibroblast phenotype, activating paracrine Hedgehog-GLI signalling in breast cancer cells

Complementary genetic screens identify the E3 ubiquitin ligase CBLC, as a modifier of PARP inhibitor sensitivity

Experimental microembolism induces localized neuritic pathology in guinea pig cerebrum

Global gene expression in pseudomyxoma peritonei, with parallel development of two immortalized cell lines

A critical role of nicotinamide phosphoribosyltransferase in human telomerase reverse transcriptase induction by resveratrol in aortic smooth muscle cells

The long non-coding RNA HOTTIP enhances pancreatic cancer cell proliferation, survival and migration

The oncogenic receptor ErbB2 modulates gemcitabine and irinotecan/SN-38 chemoresistance of human pancreatic cancer cells via hCNT1 transporter and multidrug-resistance associated protein MRP-2

microRNA-217 inhibits tumor progression and metastasis by downregulating EZH2 and predicts favorable prognosis in gastric cancer

PIM1 regulates glycolysis and promotes tumor progression in hepatocellular carcinoma

Hypoxia-inducible factor 1α (HIF-1α) and reactive oxygen species (ROS) mediates radiation-induced invasiveness through the SDF-1α/CXCR4 pathway in non-small cell lung carcinoma cells

Metformin prevents aggressive ovarian cancer growth driven by high-energy diet: similarity with calorie restriction

Quantitative phosphoproteome analysis of embryonic stem cell differentiation toward blood

LLL12, a novel small inhibitor targeting STAT3 for hepatocellular carcinoma therapy

Controlled release microspheres loaded with BMP7 suppress primary tumors from human glioblastoma

miR-942 promotes cancer stem cell-like traits in esophageal squamous cell carcinoma through activation of Wnt/β-catenin signalling pathway

Identification of new biomarkers for human papillary thyroid carcinoma employing NanoString analysis

Oncogenic KRAS sensitizes premalignant, but not malignant cells, to Noxa-dependent apoptosis through the activation of the MEK/ERK pathway

Leucine-rich α-2-glycoprotein promotes TGFβ1-mediated growth suppression in the Lewis lung carcinoma cell lines

MicroRNA-146a modulates B-cell oncogenesis by regulating Egr1

Low thyroid hormone levels improve survival in murine model for ocular melanoma

Chronic liver inflammation modifies DNA methylation at the precancerous stage of murine hepatocarcinogenesis

The pan-PI3K inhibitor GDC-0941 activates canonical WNT signaling to confer resistance in TNBC cells: resistance reversal with WNT inhibitor

Pygopus-2 promotes invasion and metastasis of hepatic carcinoma cell by decreasing E-cadherin expression

Claudin-4 is required for vasculogenic mimicry formation in human breast cancer cells

Targeting of surface alpha-enolase inhibits the invasiveness of pancreatic cancer cells

RNA-dependent protein kinase (PKR) depletes nutrients, inducing phosphorylation of AMP-activated kinase in lung cancer

High expression of small GTPase Rab3D promotes cancer progression and metastasis

Expression of programmed cell death ligand 1 (PD-L1) and prevalence of tumor-infiltrating lymphocytes (TILs) in chordoma

Combined inhibition of EGFR and c-ABL suppresses the growth of triple-negative breast cancer growth through inhibition of HOTAIR

Synaptopodin-2 induces assembly of peripheral actin bundles and immature focal adhesions to promote lamellipodia formation and prostate cancer cell migration

Inhibition of cathepsin proteases attenuates migration and sensitizes aggressive N-Myc amplified human neuroblastoma cells to doxorubicin

Low spinophilin expression enhances aggressive biological behavior of breast cancer

Esophageal adenocarcinoma and obesity: peritumoral adipose tissue plays a role in lymph node invasion

Global metabolic profile identifies choline kinase alpha as a key regulator of glutathione-dependent antioxidant cell defense in ovarian carcinoma

Resistin and interleukin-6 exhibit racially-disparate expression in breast cancer patients, display molecular association and promote growth and aggressiveness of tumor cells through STAT3 activation

New somatic mutations and WNK1-B4GALNT3 gene fusion in papillary thyroid carcinoma

E2F1 enhances glycolysis through suppressing Sirt6 transcription in cancer cells

Lipin-1 regulates cancer cell phenotype and is a potential target to potentiate rapamycin treatment

FoxM1 promotes breast tumorigenesis by activating PDGF-A and forming a positive feedback loop with the PDGF/AKT signaling pathway

Sunitinib but not VEGF blockade inhibits cancer stem cell endothelial differentiation

Targeting myeloid cells in the tumor microenvironment enhances vaccine efficacy in murine epithelial ovarian cancer

Large oncosomes contain distinct protein cargo and represent a separate functional class of tumor-derived extracellular vesicles

The hypoxia-related microRNA miR-199a-3p displays tumor suppressor functions in ovarian carcinoma

Epidermal growth factor receptor as a novel molecular target for aggressive papillary tumors in the middle ear and temporal bone

Intraperitoneal administration of tumor-targeting Salmonella typhimurium A1-R inhibits disseminated human ovarian cancer and extends survival in nude mice

B-cell precursor acute lymphoblastic leukemia and stromal cells communicate through Galectin-3

Distinct von Hippel-Lindau gene and hypoxia-regulated alterations in gene and protein expression patterns of renal cell carcinoma and their effects on metabolism

Population analysis of microsatellite genotypes reveals a signature associated with ovarian cancer

Loss of β-catenin in adrenocortical cancer cells causes growth inhibition and reversal of epithelial-to-mesenchymal transition

Amphiregulin enhances alpha6beta1 integrin expression and cell motility in human chondrosarcoma cells through Ras/Raf/MEK/ERK/AP-1 pathway

Reduction in gap junction intercellular communication promotes glioma migration

CD44 increases the efficiency of distant metastasis of breast cancer

High frequency of loss of PTEN expression in human solid salivary adenoid cystic carcinoma and its implication for targeted therapy

Metastasis-associated in colon cancer-1 promotes vasculogenic mimicry in gastric cancer by upregulating TWIST1/2

AMPK-mediated energy homeostasis and associated metabolic effects on cancer cell response and resistance to cetuximab

MTH1 expression is required for effective transformation by oncogenic HRAS

Down-regulation of ARNT promotes cancer metastasis by activating the fibronectin/integrin β1/FAK axis

Epigenetic silencing of BCL6B inactivates p53 signaling and causes human hepatocellular carcinoma cell resist to 5-FU

Inhibition of β-Catenin signaling suppresses pancreatic tumor growth by disrupting nuclear β-Catenin/TCF-1 complex: critical role of STAT-3

Autoimmune response to PARP and BRCA1/BRCA2 in cancer

TMEM16A overexpression contributes to tumor invasion and poor prognosis of human gastric cancer through TGF-β signaling

Activation of AKR1C1/ERβ induces apoptosis by downregulation of c-FLIP in prostate cancer cells: A prospective therapeutic opportunity

FTY720 enhances TRAIL-mediated apoptosis by up-regulating DR5 and down-regulating Mcl-1 in cancer cells

ψ-Bufarenogin, a novel anti-tumor compound, suppresses liver cancer growth by inhibiting receptor tyrosine kinase-mediated signaling

Connexin 43 expression is associated with increased malignancy in prostate cancer cell lines and functions to promote migration

LncRNA-ATB promotes trastuzumab resistance and invasion-metastasis cascade in breast cancer

Recurrence of glioblastoma after radio-chemotherapy is associated with an angiogenic switch to the CXCL12-CXCR4 pathway

Independent replication of a melanoma subtype gene signature and evaluation of its prognostic value and biological correlates in a population cohort

High mesothelin expression in advanced lung adenocarcinoma is associated with KRAS mutations and a poor prognosis

Tyrosine-protein phosphatase non-receptor type 12 expression is a good prognostic factor in resectable non-small cell lung cancer

Implications for selecting local excision in locally advanced rectal cancer after preoperative chemoradiation