VOLUME 6 (2015)
Table of Contents
Editorial
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| Growth hormone in adipose dysfunction and senescence |
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https://doi.org/10.18632/oncotarget.3997
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| 10667-10668 |
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| iPSCMSCs and islet allograft tolerance |
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https://doi.org/10.18632/oncotarget.4050
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| 10669-10670 |
Reviews
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| Genetic/molecular alterations of meningiomas and the signaling pathways targeted |
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https://doi.org/10.18632/oncotarget.3870
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| 10671-10688 |
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| Mutations of cCbl in myeloid malignancies |
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https://doi.org/10.18632/oncotarget.3986
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| 10689-10696 |
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| EMT CTCs and CSCs in tumor relapse and drugresistance |
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https://doi.org/10.18632/oncotarget.4037
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| 10697-10711 |
Priority Research Papers
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| Therapy of prostate cancer using a novel cancer terminator virus and a small molecule BH3 mimetic |
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https://doi.org/10.18632/oncotarget.3544
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| 10712-10727 |
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| Chemotherapy induces the cancerassociated fibroblast phenotype activating paracrine HedgehogGLI signalling in breast cancer cells |
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https://doi.org/10.18632/oncotarget.3828
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| 10728-10745 |
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| Complementary genetic screens identify the E3 ubiquitin ligase CBLC as a modifier of PARP inhibitor sensitivity |
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https://doi.org/10.18632/oncotarget.3628
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| 10746-10758 |
Research Papers: Pathology
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| Dysfunctional BLK in common variable immunodeficiency perturbs Bcell proliferation and ability to elicit antigenspecific CD4+ Tcell help |
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https://doi.org/10.18632/oncotarget.3577
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| 10759-10771 |
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| Experimental microembolism induces localized neuritic pathology in guinea pig cerebrum |
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https://doi.org/10.18632/oncotarget.3599
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| 10772-10785 |
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| Global gene expression in pseudomyxoma peritonei with parallel development of two immortalized cell lines |
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https://doi.org/10.18632/oncotarget.3198
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| 10786-10800 |
Research Papers: Gerotarget (Focus on Aging)
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| Ovariectomy shortens the life span of female mice |
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https://doi.org/10.18632/oncotarget.2984
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| 10801-10811 |
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| A critical role of nicotinamide phosphoribosyltransferase in human telomerase reverse transcriptase induction by resveratrol in aortic smooth muscle cells |
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https://doi.org/10.18632/oncotarget.3580
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| 10812-10824 |
Research Papers
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| A novel role for drebrin in regulating progranulin bioactivity in bladder cancer |
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https://doi.org/10.18632/oncotarget.3424
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| 10825-10839 |
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| The long noncoding RNA HOTTIP enhances pancreatic cancer cell proliferation survival and migration |
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https://doi.org/10.18632/oncotarget.3450
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| 10840-10852 |
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| The oncogenic receptor ErbB2 modulates gemcitabine and irinotecan/SN38 chemoresistance of human pancreatic cancer cells via hCNT1 transporter and multidrugresistance associated protein MRP2 |
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https://doi.org/10.18632/oncotarget.3414
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| 10853-10867 |
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| microRNA217 inhibits tumor progression and metastasis by downregulating EZH2 and predicts favorable prognosis in gastric cancer |
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https://doi.org/10.18632/oncotarget.3451
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| 10868-10879 |
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| PIM1 regulates glycolysis and promotes tumor progression in hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.3534
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| 10880-10892 |
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| Hypoxiainducible factor 1α HIF1α and reactive oxygen species ROS mediates radiationinduced invasiveness through the SDF1α/CXCR4 pathway in nonsmall cell lung carcinoma cells |
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https://doi.org/10.18632/oncotarget.3535
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| 10893-10907 |
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| Metformin prevents aggressive ovarian cancer growth driven by highenergy diet: similarity with calorie restriction |
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https://doi.org/10.18632/oncotarget.3434
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| 10908-10923 |
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| Quantitative phosphoproteome analysis of embryonic stem cell differentiation toward blood |
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https://doi.org/10.18632/oncotarget.3454
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| 10924-10939 |
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| LLL12 a novel small inhibitor targeting STAT3 for hepatocellular carcinoma therapy |
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https://doi.org/10.18632/oncotarget.3458
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| 10940-10949 |
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| Controlled release microspheres loaded with BMP7 suppress primary tumors from human glioblastoma |
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https://doi.org/10.18632/oncotarget.3459
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| 10950-10963 |
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| miR942 promotes cancer stem celllike traits in esophageal squamous cell carcinoma through activation of Wnt/βcatenin signalling pathway |
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https://doi.org/10.18632/oncotarget.3696
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| 10964-10977 |
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| Identification of new biomarkers for human papillary thyroid carcinoma employing NanoString analysis |
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https://doi.org/10.18632/oncotarget.3452
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| 10978-10993 |
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| Oncogenic KRAS sensitizes premalignant but not malignant cells to Noxadependent apoptosis through the activation of the MEK/ERK pathway |
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https://doi.org/10.18632/oncotarget.3552
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| 10994-11008 |
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| Leucinerich α2glycoprotein promotes TGFβ1mediated growth suppression in the Lewis lung carcinoma cell lines |
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https://doi.org/10.18632/oncotarget.3557
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| 11009-11022 |
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| MicroRNA146a modulates Bcell oncogenesis by regulating Egr1 |
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https://doi.org/10.18632/oncotarget.3433
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| 11023-11037 |
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| Low thyroid hormone levels improve survival in murine model for ocular melanoma |
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https://doi.org/10.18632/oncotarget.3566
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| 11038-11046 |
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| Chronic liver inflammation modifies DNA methylation at the precancerous stage of murine hepatocarcinogenesis |
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https://doi.org/10.18632/oncotarget.3567
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| 11047-11060 |
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| The panPI3K inhibitor GDC0941 activates canonical WNT signaling to confer resistance in TNBC cells: resistance reversal with WNT inhibitor |
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https://doi.org/10.18632/oncotarget.3568
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| 11061-11073 |
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| Pygopus2 promotes invasion and metastasis of hepatic carcinoma cell by decreasing Ecadherin expression |
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https://doi.org/10.18632/oncotarget.3570
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| 11074-11086 |
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| Claudin4 is required for vasculogenic mimicry formation in human breast cancer cells |
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https://doi.org/10.18632/oncotarget.3571
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| 11087-11097 |
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| Targeting of surface alphaenolase inhibits the invasiveness of pancreatic cancer cells |
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https://doi.org/10.18632/oncotarget.3572
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| 11098-11113 |
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| RNAdependent protein kinase PKR depletes nutrients inducing phosphorylation of AMPactivated kinase in lung cancer |
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https://doi.org/10.18632/oncotarget.3573
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| 11114-11124 |
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| High expression of small GTPase Rab3D promotes cancer progression and metastasis |
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https://doi.org/10.18632/oncotarget.3575
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| 11125-11138 |
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| Expression of programmed cell death ligand 1 PDL1 and prevalence of tumorinfiltrating lymphocytes TILs in chordoma |
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https://doi.org/10.18632/oncotarget.3576
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| 11139-11149 |
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| Combined inhibition of EGFR and cABL suppresses the growth of triplenegative breast cancer growth through inhibition of HOTAIR |
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https://doi.org/10.18632/oncotarget.3441
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| 11150-11161 |
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| Synaptopodin2 induces assembly of peripheral actin bundles and immature focal adhesions to promote lamellipodia formation and prostate cancer cell migration |
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https://doi.org/10.18632/oncotarget.3578
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| 11162-11174 |
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| Inhibition of cathepsin proteases attenuates migration and sensitizes aggressive NMyc amplified human neuroblastoma cells to doxorubicin |
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https://doi.org/10.18632/oncotarget.3579
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| 11175-11190 |
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| Low spinophilin expression enhances aggressive biological behavior of breast cancer |
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https://doi.org/10.18632/oncotarget.3586
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| 11191-11202 |
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| Esophageal adenocarcinoma and obesity: peritumoral adipose tissue plays a role in lymph node invasion |
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https://doi.org/10.18632/oncotarget.3587
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| 11203-11215 |
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| Global metabolic profile identifies choline kinase alpha as a key regulator of glutathionedependent antioxidant cell defense in ovarian carcinoma |
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https://doi.org/10.18632/oncotarget.3589
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| 11216-11230 |
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| Resistin and interleukin6 exhibit raciallydisparate expression in breast cancer patients display molecular association and promote growth and aggressiveness of tumor cells through STAT3 activation |
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https://doi.org/10.18632/oncotarget.3591
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| 11231-11241 |
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| New somatic mutations and WNK1B4GALNT3 gene fusion in papillary thyroid carcinoma |
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https://doi.org/10.18632/oncotarget.3593
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| 11242-11251 |
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| E2F1 enhances glycolysis through suppressing Sirt6 transcription in cancer cells |
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https://doi.org/10.18632/oncotarget.3594
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| 11252-11263 |
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| Lipin1 regulates cancer cell phenotype and is a potential target to potentiate rapamycin treatment |
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https://doi.org/10.18632/oncotarget.3595
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| 11264-11280 |
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| FoxM1 promotes breast tumorigenesis by activating PDGFA and forming a positive feedback loop with the PDGF/AKT signaling pathway |
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https://doi.org/10.18632/oncotarget.3596
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| 11281-11294 |
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| Sunitinib but not VEGF blockade inhibits cancer stem cell endothelial differentiation |
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https://doi.org/10.18632/oncotarget.3123
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| 11295-11309 |
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| Targeting myeloid cells in the tumor microenvironment enhances vaccine efficacy in murine epithelial ovarian cancer |
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https://doi.org/10.18632/oncotarget.3597
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| 11310-11326 |
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| Large oncosomes contain distinct protein cargo and represent a separate functional class of tumorderived extracellular vesicles |
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https://doi.org/10.18632/oncotarget.3598
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| 11327-11341 |
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| The hypoxiarelated microRNA miR199a3p displays tumor suppressor functions in ovarian carcinoma |
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https://doi.org/10.18632/oncotarget.3604
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| 11342-11356 |
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| Epidermal growth factor receptor as a novel molecular target for aggressive papillary tumors in the middle ear and temporal bone |
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https://doi.org/10.18632/oncotarget.3605
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| 11357-11368 |
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| Intraperitoneal administration of tumortargeting Salmonella typhimurium A1R inhibits disseminated human ovarian cancer and extends survival in nude mice |
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https://doi.org/10.18632/oncotarget.3607
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| 11369-11377 |
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| Bcell precursor acute lymphoblastic leukemia and stromal cells communicate through Galectin3 |
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https://doi.org/10.18632/oncotarget.3409
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| 11378-11394 |
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| Distinct von HippelLindau gene and hypoxiaregulated alterations in gene and protein expression patterns of renal cell carcinoma and their effects on metabolism |
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https://doi.org/10.18632/oncotarget.3456
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| 11395-11406 |
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| Population analysis of microsatellite genotypes reveals a signature associated with ovarian cancer |
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https://doi.org/10.18632/oncotarget.2933
|
| 11407-11420 |
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| Loss of tenin in adrenocortical cancer cells causes growth inhibition and reversal of epithelialtomesenchymal transition |
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https://doi.org/10.18632/oncotarget.3222
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| 11421-11433 |
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| Amphiregulin enhances alpha6beta1 integrin expression and cell motility in human chondrosarcoma cells through Ras/Raf/MEK/ERK/AP1 pathway |
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https://doi.org/10.18632/oncotarget.3397
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| 11434-11446 |
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| Reduction in gap junction intercellular communication promotes glioma migration |
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https://doi.org/10.18632/oncotarget.3407
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| 11447-11464 |
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| CD44 increases the efficiency of distant metastasis of breast cancer |
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https://doi.org/10.18632/oncotarget.3410
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| 11465-11476 |
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| High frequency of loss of PTEN expression in human solid salivary adenoid cystic carcinoma and its implication for targeted therapy |
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https://doi.org/10.18632/oncotarget.3411
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| 11477-11491 |
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| Metastasisassociated in colon cancer1 promotes vasculogenic mimicry in gastric cancer by upregulating TWIST1/2 |
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https://doi.org/10.18632/oncotarget.3416
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| 11492-11506 |
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| AMPKmediated energy homeostasis and associated metabolic effects on cancer cell response and resistance to cetuximab |
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https://doi.org/10.18632/oncotarget.3432
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| 11507-11518 |
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| MTH1 expression is required for effective transformation by oncogenic HRAS |
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https://doi.org/10.18632/oncotarget.3447
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| 11519-11529 |
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| Downregulation of ARNT promotes cancer metastasis by activating the fibronectin/integrin β1/FAK axis |
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https://doi.org/10.18632/oncotarget.3448
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| 11530-11546 |
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| Epigenetic silencing of BCL6B inactivates p53 signaling and causes human hepatocellular carcinoma cell resist to 5FU |
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https://doi.org/10.18632/oncotarget.3413
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| 11547-11560 |
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| Inhibition of βCatenin signaling suppresses pancreatic tumor growth by disrupting nuclear βCatenin/TCF1 complex: critical role of STAT3 |
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https://doi.org/10.18632/oncotarget.3427
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| 11561-11574 |
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| Autoimmune response to PARP and BRCA1/BRCA2 in cancer |
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https://doi.org/10.18632/oncotarget.3428
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| 11575-11584 |
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| TMEM16A overexpression contributes to tumor invasion and poor prognosis of human gastric cancer through TGFβ signaling |
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https://doi.org/10.18632/oncotarget.3412
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| 11585-11599 |
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| Activation of AKR1C1/ERβ induces apoptosis by downregulation of cFLIP in prostate cancer cells: A prospective therapeutic opportunity |
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https://doi.org/10.18632/oncotarget.3417
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| 11600-11613 |
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| FTY720 enhances TRAILmediated apoptosis by upregulating DR5 and downregulating Mcl1 in cancer cells |
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https://doi.org/10.18632/oncotarget.3426
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| 11614-11626 |
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| ψBufarenogin a novel antitumor compound suppresses liver cancer growth by inhibiting receptor tyrosine kinasemediated signaling |
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https://doi.org/10.18632/oncotarget.3435
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| 11627-11639 |
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| Connexin 43 expression is associated with increased malignancy in prostate cancer cell lines and functions to promote migration |
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https://doi.org/10.18632/oncotarget.3449
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| 11640-11651 |
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| LncRNAATB promotes trastuzumab resistance and invasionmetastasis cascade in breast cancer |
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https://doi.org/10.18632/oncotarget.3457
|
| 11652-11663 |
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| Recurrence of glioblastoma after radiochemotherapy is associated with an angiogenic switch to the CXCL12CXCR4 pathway |
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https://doi.org/10.18632/oncotarget.3256
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| 11664-11675 |
Clinical Research Papers
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| MicroRNA profiling of Chinese primary glioblastoma reveals a temozolomidechemoresistant subtype |
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https://doi.org/10.18632/oncotarget.3258
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| 11676-11682 |
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| Independent replication of a melanoma subtype gene signature and evaluation of its prognostic value and biological correlates in a population cohort |
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https://doi.org/10.18632/oncotarget.3549
|
| 11683-11693 |
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| High mesothelin expression in advanced lung adenocarcinoma is associated with KRAS mutations and a poor prognosis |
|
https://doi.org/10.18632/oncotarget.3429
|
| 11694-11703 |
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| Tyrosineprotein phosphatase nonreceptor type 12 expression is a good prognostic factor in resectable nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.3588
|
| 11704-11713 |
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| Implications for selecting local excision in locally advanced rectal cancer after preoperative chemoradiation |
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https://doi.org/10.18632/oncotarget.3418
|
| 11714-11722 |
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